1-Methylbenzotriazole supplier

Name
1-Methylbenzotriazole
EINECS 249-596-6
CAS No. 13351-73-0
Article Data55
CAS DataBase
Density 1.24 g/cm³
Solubility
Melting Point 64-65°C
Formula C₇H₇N₃
Boiling Point 270.5 °C at 760 mmHg
Molecular Weight 133.153
Flash Point 117.4 °C
Transport Information
Appearance
Safety 22-24/25
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms 1-Methyl-1,2,3-benzotriazole;1-Methyl-1H-benzotriazole;1-Methylbenzotriazole;NSC 11743;
PSA 30.71000
LogP 0.96830

Synthetic route

: 95-14-7
1,2,3-Benzotriazole

: 4637-24-5
N,N-dimethyl-formamide dimethyl acetal

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 90℃; for 4h;	87.8%

: 917-64-6
methyl magnesium iodide

: 54187-96-1
1-(chloromethyl)-1H-benzotriazole

A: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

B: 16584-05-7
1-ethylbenzotriazole

Conditions

Conditions	Yield
In diethyl ether for 1h; Ambient temperature;	A 83% B 11%

...Expand

: 95-14-7
1,2,3-Benzotriazole

: P-(dichloromethyl) O-methyl chlorophosphonate

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 0 - 5℃; for 1h; Alkylation;	80%

: 95-14-7
1,2,3-Benzotriazole

: 74-88-4
methyl iodide

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

Conditions

Conditions	Yield
With sodium hydroxide In water; acetonitrile for 48h;	73%
With potassium tert-butylate; 18-crown-6 ether In diethyl ether for 1h; Ambient temperature;	70%
Stage #1: 1,2,3-Benzotriazole With sodium hydride In tetrahydrofuran; mineral oil for 0.0833333h; Stage #2: With carbon disulfide In tetrahydrofuran; mineral oil at 0 - 5℃; Stage #3: methyl iodide In tetrahydrofuran; mineral oil at 0 - 5℃; for 0.2h;	67%
With sodium hydroxide In water; acetonitrile at 20℃; for 48h;	55%

: 86298-22-8
1H-benzotriazole-1-carboxylic acid methyl ester

A: 16584-00-2
2-methylbenzotriazole

B: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

Conditions

Conditions	Yield
at 120℃; Title compound not separated from byproducts;	A 29% B 71%
at 160℃;
at 160℃;
at 120℃; Mechanism; other alkoxycarbonylbenzotriazoles;	A 29 % Spectr. B 71 % Spectr.

: 1334478-48-6
1-benzyl-3-methylbenzotriazolium iodide

A: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

B: 103-30-0
(E)-1,2-diphenyl-ethene

Conditions

Conditions	Yield
With sodium hydride In dimethyl sulfoxide at 20℃; stereoselective reaction;	A n/a B 68%

: 21050-95-3
N-chlorobenzotriazole

A: 95-14-7
1,2,3-Benzotriazole

B: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

C: 68407-95-4
1-iodobenzotriazole

D: 1,3-dimethylbenzotriazolium triiodide

Conditions

Conditions	Yield
With methyl iodide In dichloromethane at 42℃; for 1h;	A 10% B 6% C 65% D 19%
With methyl iodide In dichloromethane at 42℃; for 3h;	A 18% B 11% C 41% D 30%

...Expand

: 95-14-7
1,2,3-Benzotriazole

: 77-78-1
dimethyl sulfate

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

Conditions

Conditions	Yield
With sodium hydroxide at 20℃; for 2.5h;	65%
With sodium hydroxide In water at 20 - 80℃; for 0.75h;

: 127236-78-6
N-(benzotriazol-1-ylmethyl)-N-methylpyrrolidinium iodide

: 6921-34-2
benzylmagnesium chloride

A: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

B: 63777-68-4
1-phenethyl-1H-benzo[d][1,2,3]triazole

Conditions

Conditions	Yield
In tetrahydrofuran; diethyl ether at 45℃; for 3h;	A n/a B 64%

...Expand

: 4760-34-3
N-methyl-1,2-phenylenediamine

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

Conditions

Conditions	Yield
With tert.-butylhydroperoxide; nitromethane; caesium carbonate; acetic acid; potassium iodide In water at 120℃; for 12h; Schlenk technique; Inert atmosphere; chemoselective reaction;	62%
With hydrogenchloride Diazotization.und Verkochen das entstandende Diazoniumsalz;

: 95-14-7
1,2,3-Benzotriazole

: 74-88-4
methyl iodide

A: 16584-00-2
2-methylbenzotriazole

B: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

Conditions

Conditions	Yield
With sodium hydroxide In N,N-dimethyl-formamide for 0.5h;	A 40% B 60%
With potassium hydroxide; tetrabutylammomium bromide at 0℃; Yields of byproduct given;	A 25% B n/a
With sodium hydroxide In N,N-dimethyl-formamide for 0.25h; Ambient temperature; Yield given. Yields of byproduct given;
With potassium hydroxide; tetrabutylammomium bromide Ambient temperature; Irradiation; Yield given. Yields of byproduct given;
With potassium hydroxide; 1-butyl-3-methylimidazolium Tetrafluoroborate at 20℃; for 2h;

...Expand

: 553-90-2
Dimethyl oxalate

: 95-14-7
1,2,3-Benzotriazole

A: 16584-00-2
2-methylbenzotriazole

B: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

Conditions

Conditions	Yield
With potassium tert-butylate In N,N-dimethyl-formamide Heating;	A 35% B 59%
With potassium tert-butylate In N,N-dimethyl-formamide for 3h; Heating;	A 35% B 59%
With potassium tert-butylate In N,N-dimethyl-formamide for 3h; Heating;	A 35% B 59%

...Expand

: 610-17-3
N,N-dimethyl-2-nitro-benzenamine

A: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

B: 89937-90-6
N-nitroso N-methyl-N-(2-nitroaniline)

C: 614-00-6
N-methyl-N-nitrosoaniline

D: 612-28-2
2-nitro-N-methylaniline

Conditions

Conditions	Yield
With n-Butyl nitrite; ammonium chloride; water for 2h; Heating; Further byproducts given;	A 7% B 58% C 9% D 5%

...Expand

: 610-17-3
N,N-dimethyl-2-nitro-benzenamine

A: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

B: 89937-90-6
N-nitroso N-methyl-N-(2-nitroaniline)

C: 612-28-2
2-nitro-N-methylaniline

D: 98-95-3
nitrobenzene

Conditions

Conditions	Yield
With n-Butyl nitrite; ammonium chloride; water for 2h; Mechanism; Heating;	A 7% B 58% C 5% D 1%

...Expand

: 37922-13-7
1-benzyl-3-methylbenzotriazolium bromide

A: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

B: 103-30-0
(E)-1,2-diphenyl-ethene

Conditions

Conditions	Yield
With sodium hydride In dimethyl sulfoxide at 20℃; stereoselective reaction;	A n/a B 56%

: 21050-95-3
N-chlorobenzotriazole

: 74-88-4
methyl iodide

A: 95-14-7
1,2,3-Benzotriazole

B: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

C: 68407-95-4
1-iodobenzotriazole

D: 1,3-dimethylbenzotriazolium triiodide

Conditions

Conditions	Yield
In dichloromethane at 42℃; for 7h;	A 8% B 21% C 16% D 55%
In dichloromethane at 42℃; for 5h;	A 8% B 28% C 29% D 35%

...Expand

: 21050-95-3
N-chlorobenzotriazole

: 74-88-4
methyl iodide

A: 95-14-7
1,2,3-Benzotriazole

B: 16584-00-2
2-methylbenzotriazole

C: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

D: 1,3-dimethylbenzotriazolium triiodide

Conditions

Conditions	Yield
In dichloromethane at 42℃; for 3h; Further byproducts given;	A 8% B 3% C 33% D 49%

...Expand

: 147861-10-7
(E)-benzotriazole-1-carbaldehyde oxime

: 74-88-4
methyl iodide

A: 16584-00-2
2-methylbenzotriazole

B: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

C: (E)-1-formylbenzotriazole O-methyloxime

Conditions

Conditions	Yield
With sodium ethanolate In ethanol at 25℃; for 24h;	A 12% B 42% C 26%

...Expand

: 75-91-2
tert.-butylhydroperoxide

: 95-14-7
1,2,3-Benzotriazole

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

Conditions

Conditions	Yield
With tetra-(n-butyl)ammonium iodide In water; acetonitrile at 100℃; for 8h; Schlenk technique; Inert atmosphere; regioselective reaction;	42%

: 95-14-7
1,2,3-Benzotriazole

: 4637-24-5
N,N-dimethyl-formamide dimethyl acetal

A: 16584-00-2
2-methylbenzotriazole

B: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

Conditions

Conditions	Yield
In toluene for 0.5h; Heating;	A 38% B 10%

...Expand

: 127236-78-6
N-(benzotriazol-1-ylmethyl)-N-methylpyrrolidinium iodide

A: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

B: 88064-00-0
1-[(1H-benzotriazol-1-yl)methyl]-1H-benzotriazole

Conditions

Conditions	Yield
In diphenylether at 200℃; for 2h;	A 15% B 38%

: 127236-78-6
N-(benzotriazol-1-ylmethyl)-N-methylpyrrolidinium iodide

: 91-66-7
N,N-diethylaniline

A: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

B: 16584-05-7
1-ethylbenzotriazole

C: 88064-00-0
1-[(1H-benzotriazol-1-yl)methyl]-1H-benzotriazole

Conditions

Conditions	Yield
at 200℃; for 4h;	A 8% B 37% C 28%

...Expand

: 65763-68-0
N-bromobenzotriazole

: 74-88-4
methyl iodide

A: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

B: 1,3-dimethylbenzotriazolium triiodide

Conditions

Conditions	Yield
In dichloromethane at 42℃; for 3h;	A 26% B 35%

...Expand

: 6-chloro-1-methyl-4-nitrobenzotriazole

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

Conditions

Conditions	Yield
With hydrazine hydrate In ethanol at 70℃; for 90h;	32%

: 1-amino-3-methylbenzimidazolium chloride

A: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

B: 93-61-8
N-methyl-N-phenylformamide

Conditions

Conditions	Yield
With lead(IV) acetate In methanol for 0.5h; Ambient temperature;	A 20.2% B 17.2%

: 88-73-3
2-Chloronitrobenzene

: 60-34-4
methylhydrazine

A: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

B: 22713-36-6
3-methyl-3H-1,2,3-benzotriazole 1-oxide

C: 612-28-2
2-nitro-N-methylaniline

D: 95-51-2
2-Chloroaniline

Conditions

Conditions	Yield
In ethanol at 150℃; for 5h;	A 12% B n/a C n/a D 20%

...Expand

: 68407-95-4
1-iodobenzotriazole

: 74-88-4
methyl iodide

A: 95-14-7
1,2,3-Benzotriazole

B: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

C: 1,3-dimethylbenzotriazolium triiodide

Conditions

Conditions	Yield
In dichloromethane at 42℃; for 3h;	A 10% B 10% C 12%

...Expand

: 68407-95-4
1-iodobenzotriazole

A: 95-14-7
1,2,3-Benzotriazole

B: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

C: 1,3-dimethylbenzotriazolium triiodide

Conditions

Conditions	Yield
With methyl iodide In dichloromethane at 42℃; for 3h;	A 10% B 10% C 12%

...Expand

: 186581-53-3, 908094-01-9
diazomethane

: 95-14-7
1,2,3-Benzotriazole

A: 16584-00-2
2-methylbenzotriazole

B: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

Conditions

Conditions	Yield
With ethanol

...Expand

: 54187-96-1
1-(chloromethyl)-1H-benzotriazole

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

Conditions

Conditions	Yield
With lithium aluminium tetrahydride
Multi-step reaction with 2 steps 1: 40 percent / methanol / 1 h / Heating 2: toluene; diethyl ether / Heating View Scheme
Multi-step reaction with 2 steps 1: 87 percent / toluene; methanol / 2 h / Heating 2: benzene; diethyl ether / Heating View Scheme

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

: 14044-65-6
borane-THF

: 1201669-53-5
N-1-methyl-benzotriazole-N-3-borane

Conditions

Conditions	Yield
In not given (C6H4N3)Me (1.1 equiv.), 1.0 M BH3*THF (1.0 equiv.), room temp.;	99%
In tetrahydrofuran for 2h; Cooling with ice;	84%

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

: 1201669-53-5
N-1-methyl-benzotriazole-N-3-borane

Conditions

Conditions	Yield
With borane-THF In tetrahydrofuran at 20℃; Inert atmosphere;	99%

: gold(III) chloride

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

: 2923-28-6
silver trifluoromethanesulfonate

: C34H43AuN5(1+)*CF3O3S(1-)

Conditions

Conditions	Yield
In methanol at 20℃; for 6h;	97%

...Expand

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

: nickel(II) chloride hexahydrate

: Ni(2+)*2Cl(1-)*C6N3H4CH3=NiCl2(C6N3H4CH3)

Conditions

Conditions	Yield
With triethyl orthoformate In ethanol to a soln. of NiCl2*6H2O in abs. ethanol was added CH(OEt)3, refluxed for 30 min, addn. of the triazole (molar ratio 1:1); filtered, washed with ethanol and Et2O, dried in vac. over silica gel; elem. anal.;	96%

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

: cobalt(II) bromide

: 146262-41-1
(Br2)(1-methylbenzotriazolyl)2cobalt(II)

Conditions

Conditions	Yield
In ethanol dropwise addn. of CoBr2 in absolute EtOH to a stirred solution of ligand in absolute EtOH (under aerobic conditions), forming ppt., further stirring for 30 min; filtn., washing with EtOH and diethyl ether, drying in vacuo over silica gel, elem. anal.;	95%

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

: 229-87-8
phenanthridine

: 922-67-8
propynoic acid methyl ester

: (E)-methyl 3-(6-(1H-benzo[d][1,2,3]triazol-1-yl)phenanthridin-5(6H)-yl)acrylate

Conditions

Conditions	Yield
In dichloromethane at -10 - 20℃;	91%

...Expand

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

: 22713-36-6
3-methyl-3H-1,2,3-benzotriazole 1-oxide

Conditions

Conditions	Yield
With 3,3-dimethyldioxirane In dichloromethane at 20℃; for 24h;	90%

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

: 229-87-8
phenanthridine

: 623-47-2
propynoic acid ethyl ester

: (E)-ethyl 3-(6-(1H-benzo[d][1,2,3]triazol-1-yl)phenanthridin-5(6H)-yl)acrylate

Conditions

Conditions	Yield
In dichloromethane at -10 - 20℃;	90%

...Expand

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

: 91-78-1
1,3,5-triphenylhexahydro-1,3,5-triazine

Conditions

Conditions	Yield
at 700℃; under 0.01 Torr; Elimination; Cyclotrimerization;	89%

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

: cobalt(II) chloride hexahydrate

: 146262-39-7
(MebtaH)((chloro)3(1-methylbenzotriazolyl)cobaltate(II))

Conditions

Conditions	Yield
With concd. HCl In ethanol addn. of CoCl2*6H2O in concd. HCl-EtOH to a stirred soln. of ligand in concd. HCl-EtOH (under aerobic conditions), formation of ppt.; filtn., washing with EtOH and diethyl ether, drying in vacuo over silica gel, elem. anal.;	89%

: 99-75-2
4-methyl-benzoic acid methyl ester

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

: 189343-47-3
2-(1H-1,2,3-benzotriazol-1-yl)-1-(4-methylphenyl)-1-ethanone

Conditions

Conditions	Yield
With n-butyllithium In tetrahydrofuran; hexane at -78 - 20℃; for 12h;	88%

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

: 110-42-9
Methyl decanoate

: 189343-46-2
1-Benzotriazol-1-yl-undecan-2-one

Conditions

Conditions	Yield
With n-butyllithium In tetrahydrofuran; hexane at -78 - 20℃; for 12h;	88%

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

: 7789-45-9
copper(ll) bromide

: 88177-45-1
CuBr2(C6H4N3CH3)

Conditions

Conditions	Yield
In acetone room temp. (overnight); filtering, washing (Me2CO, Et2O), drying (vac., over SiO2); elem. anal.;	88%

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

: 615-22-5
2-methylmercaptobenzothiazole

: 156272-74-1
1-(1,3-Benzothiazol-2-ylmethyl)-1H-1,2,3-benzotriazole

Conditions

Conditions	Yield
With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 24h;	85%

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

: nickel(II) chloride hexahydrate

: Ni(2+)*2Cl(1-)*2C6N3H4CH3=NiCl2(C6N3H4CH3)2

Conditions

Conditions	Yield
With triethyl orthoformate In ethanol to a soln. of NiCl2*6H2O in abs. ethanol was added CH(OEt)3, refluxed for 30 min, addn. of the triazole (molar ratio 1:2); filtered, washed with ethanol and Et2O, dried in vac. over silica gel; elem. anal.;	85%

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

: 3017-60-5
cobalt(II) thiocyanate

: 146262-43-3
(cobalt(isothiocyanate)2(1-methylbenzotriazole)2)

Conditions

Conditions	Yield
In acetone addn. of solid ligand to a stirred soln. of Co(NCS)2 in acetone (under aerobic conditions), stirring for 10 min at room temp.; filtn., addn. of n-hexane to the filtrate to yield dark blue oil, solidification on overnight storage in a freezer, collection by filtn., washing with n-hexane, drying in vacuo over silica gel, elem. anal.;	84%

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

: 123-29-5
ethyl pelargonate

: 189343-45-1
1-Benzotriazol-1-yl-decan-2-one

Conditions

Conditions	Yield
With n-butyllithium In tetrahydrofuran; hexane at -78 - 20℃; for 12h;	83%

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

: 7646-79-9
cobalt(II) chloride

: 146262-37-5
(chloro)2(1-methylbenzotriazolyl)2cobalt(II)

Conditions

Conditions	Yield
In ethanol dropwise addn. of CoCl2 in absolute EtOH to a stirred solution of ligand in absolute EtOH (under aerobic conditions), forming ppt., further stirring for 30 min; filtn., washing with EtOH and diethyl ether, drying in vacuo over silica gel, elem. anal.;	83%

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

: 70-11-1
α-bromoacetophenone

: 132416-78-5
3-methyl-1-phenacylbenzotriazolium bromide

Conditions

Conditions	Yield
In toluene for 5h; Heating;	80%
In ethyl acetate for 3h; Heating;	72%

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

: 13689-92-4
nickel(II) thiocyanate

: 157037-34-8
Ni(NCS)2(CH3OH)2(C6N3H4CH3)2

Conditions

Conditions	Yield
With methanol In methanol the triazole was dissolved with stirring in a soln. of Ni(SCN)2 in refluxing methanol, left undisturbed at ambient temp.; filtered, washed with Et2O, dried in air; elem. anal.;	80%

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

: copper dichloride

: [Cu2Cl4(1-methylbenzotriazole)2]n

Conditions

Conditions	Yield
With HC(OEt)3 In ethanol dissoln. of equimolar amts. of CuCl2 and ligand in EtOH contg. HC(COEt)3; crystn. (2 d, room temp.), filtration, washing (Et2O), drying (vac.); elem. anal.;	80%

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

: 123-66-0
Ethyl hexanoate

: 189343-44-0
1-(1H-1,2,3-benzotriazol-1-yl)-2-heptanone

Conditions

Conditions	Yield
With n-butyllithium In tetrahydrofuran; hexane at -78 - 20℃; for 12h;	78%

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

: nickel(II) nitrate hexahydrate

: 157037-29-1
Ni(NO3)2(C6N3H4CH3)4

Conditions

Conditions	Yield
With triethyl orthoformate In ethanol to a soln. of the triazole in abs. ethanol was added a soln. of Ni(NO3)2*6H2O in the same solvent, addn. of CH(OEt)3, refluxed for 30 min; addn. of Et2O to the cooled soln., filtered, washed with Et2O, dried in vac. over silica gel; elem. anal.;	78%

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

methyl trifluoromethanesulfonate: methyl trifluoromethanesulfonate

1,3-Dimethylbenzotriazolium trifluoromethanesulphonate: 1,3-Dimethylbenzotriazolium trifluoromethanesulphonate

Conditions

Conditions	Yield
In dichloromethane for 144h; Ambient temperature;	77%

: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

(triphenylphosphine)gold(I) chloride: (triphenylphosphine)gold(I) chloride

: 2923-28-6
silver trifluoromethanesulfonate

: 1186016-23-8
triazole

Conditions

Conditions	Yield
Stage #1: (triphenylphosphine)gold(I) chloride; silver trifluoromethanesulfonate In methanol for 0.0833333h; Inert atmosphere; Stage #2: 1-methyl-1H-benzo[d][1,2,3]triazole In methanol at 20℃; for 12h; Inert atmosphere;	76%
byproducts: AgCl;

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: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

: 75-05-8
acetonitrile

: 7789-45-9
copper(ll) bromide

: 255913-57-6
CuBr2(C6H4N3CH3)2(CH3CN)

Conditions

Conditions	Yield
In acetonitrile room temp. (24 h); filtering, washing (Et2O), drying; elem. anal.;	75%

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: 13351-73-0
1-methyl-1H-benzo[d][1,2,3]triazole

: nickel(II) bromide trihydrate

: 157037-39-3
NiBr2(CH3OH)2(C6N3H4CH3)2

Conditions

Conditions	Yield
With triethyl orthoformate In methanol to a stirred soln. of NiBr2*3H2O in abs. methanol were added CH(OEt)3 and a soln. of the triazole in abs. methanol, refluxed for 30 min; layered with Et2O at 4°C, slow mixing, filtered, washed with Et2O, dried in air; elem. anal.;	74%

1-Methylbenzotriazole Specification

The 1H-Benzotriazole,1-methyl-, with CAS registry number 13351-73-0, has the systematic name of 1-methyl-1H-benzotriazole. Besides this, it is also called 1-Methylbenzotriazole. And the chemical formula of this chemical is C₇H₇N₃. What's more, its EINECS is 236-401-4. When use it, do not breathe dust and avoid contact with skin and eyes.

Physical properties of 1H-Benzotriazole,1-methyl-: (1)ACD/LogP: 1.06; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.06; (4)ACD/LogD (pH 7.4): 1.06; (5)ACD/BCF (pH 5.5): 3.74; (6)ACD/BCF (pH 7.4): 3.74; (7)ACD/KOC (pH 5.5): 89.52; (8)ACD/KOC (pH 7.4): 89.53; (9)#H bond acceptors: 3; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 30.71 Å²; (13)Index of Refraction: 1.658; (14)Molar Refractivity: 39.58 cm³; (15)Molar Volume: 107.3 cm³; (16)Polarizability: 15.69×10^-24cm³; (17)Surface Tension: 47 dyne/cm; (18)Density: 1.24 g/cm³; (19)Flash Point: 117.4 °C; (20)Enthalpy of Vaporization: 48.82 kJ/mol; (21)Boiling Point: 270.5 °C at 760 mmHg; (22)Vapour Pressure: 0.0113 mmHg at 25°C.

Preparation: this chemical can be prepared by 1H-benzotriazole and iodomethane. This reaction will need reagent sodium hydroxide and solvents acetonitrile, H₂O. The reaction time is 2 day(s). The yield is about 73%.

You can still convert the following datas into molecular structure:
(1)SMILES: n1nn(c2ccccc12)C
(2)InChI: InChI=1/C7H7N3/c1-10-7-5-3-2-4-6(7)8-9-10/h2-5H,1H3
(3)InChIKey: HXQHRUJXQJEGER-UHFFFAOYAL
(4)Std. InChI: InChI=1S/C7H7N3/c1-10-7-5-3-2-4-6(7)8-9-10/h2-5H,1H3
(5)Std. InChIKey: HXQHRUJXQJEGER-UHFFFAOYSA-N

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intravenous	375mg/kg (375mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 486, 1952.

Product Name

1-Methylbenzotriazole

Synthetic route

1-Methylbenzotriazole Specification

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