2,3-DIMETHYLPYRAZINE supplier

Name
2,3-Dimethylpyrazine
EINECS 227-630-0
CAS No. 5910-89-4
Article Data25
CAS DataBase
Density 0.997 g/cm³
Solubility
Melting Point 11-13 °C
Formula C₆H₈N₂
Boiling Point 158.1 °C at 760 mmHg
Molecular Weight 108.143
Flash Point 54.4 °C
Transport Information UN 1993 3/PG 3
Appearance clear yellow to orange liquid
Safety 16-26-39
Risk Codes 10-22-37/38-41
Molecular Structure
Hazard Symbols Xn, F, Xi
Synonyms Pyrazine, 2,3-dimethyl-;2,3-Dimethyl-1,4-diazine;FEMA No. 3271;2,3-Di Methyl Pyrazine;
PSA 25.78000
LogP 1.09340

Synthetic route

: 107-15-3
ethylenediamine

: 431-03-8
dimethylglyoxal

: 5910-89-4
2,3-dimethylpyrazine

Conditions

Conditions	Yield
With γ-maghemite-silica nanocomposite In neat (no solvent) at 55℃; for 6h; Green chemistry;	94%
With diethyl ether at 0℃; Erwaermen des Reaktionsprodukts und Oxydation des erhaltenen 2.3-Dimethyl-5.6-dihydro-pyrazins mit Fehlingscher Loesung;

: 41110-52-5
5,6-dimethyl-2,3-pyrazinedicarboxylic acid

: 64-19-7
acetic acid

: 5910-89-4
2,3-dimethylpyrazine

Conditions

Conditions	Yield
at 180℃;

: 57193-34-7, 57193-35-8, 84468-52-0
2,3-dimethyl-piperazine

: 5910-89-4
2,3-dimethylpyrazine

Conditions

Conditions	Yield
With aluminum oxide; copper oxide-chromium oxide silicon dioxide aluminium oxide catalyst; water; silica gel at 350 - 400℃;

: 41110-52-5
5,6-dimethyl-2,3-pyrazinedicarboxylic acid

: 5910-89-4
2,3-dimethylpyrazine

Conditions

Conditions	Yield
In acetic acid at 200℃; for 1h; Yield given;

: 72725-81-6
2-<2-Hydroxy-2-(p-methoxyphenyl)ethyl>-3-methylpyrazine

A: 5910-89-4
2,3-dimethylpyrazine

B: 123-11-5
4-methoxy-benzaldehyde

Conditions

Conditions	Yield
In diethylene glycol dimethyl ether at 170℃; Rate constant;

: 54-17-1, 492-61-5, 492-62-6, 492-66-0, 530-25-6, 530-26-7, 530-27-8, 530-28-9, 552-76-1, 579-36-2, 643-69-6, 655-45-8, 2280-44-6, 3646-73-9, 7282-78-2, 7282-79-3, 7282-80-6, 7282-81-7, 7282-82-8, 7283-02-5, 7283-08-1, 7283-09-2, 7283-10-5, 7283-11-6, 7296-15-3, 7296-64-2, 7322-31-8, 10257-28-0, 12772-65-5, 12773-29-4, 12773-31-8, 12773-32-9, 12773-33-0, 12773-34-1, 19982-85-5, 28538-24-1, 32445-46-8, 32445-47-9, 32445-51-5, 32445-52-6, 34685-56-8, 34685-57-9, 35810-56-1, 39281-65-7, 39281-66-8, 39281-67-9, 39281-68-0, 39281-69-1, 39392-61-5, 39392-62-6, 39392-63-7, 39392-65-9, 39392-66-0, 39392-69-3, 40825-84-1, 40825-86-3, 40825-87-4, 40825-89-6, 42752-07-8, 42789-83-3, 46032-76-2, 54808-89-8, 66069-07-6, 120442-57-1, 120442-58-2, 120442-59-3, 120442-67-3, 131064-91-0, 131064-92-1, 131065-00-4, 131065-01-5, 131348-38-4
D-(+)-Glucose

A: 290-37-9
1,4-pyrazine

B: 109-08-0
2-Methylpyrazine

C: 123-32-0
2,5-dimethyl-pyrazine

D: 5910-89-4
2,3-dimethylpyrazine

E: 108-50-9
2,6-dimethylpyrazine

F: 14667-55-1
2,3,5-trimethylpyrazine

Conditions

Conditions	Yield
With ammonium hydroxide In glycerol for 9h; Product distribution; Heating; also with amino acids;

...Expand

5.6-dimethyl-pyrazine-dicarboxylic acid-(2.3): 5.6-dimethyl-pyrazine-dicarboxylic acid-(2.3)

: 5910-89-4
2,3-dimethylpyrazine

Conditions

Conditions	Yield
With acetic acid at 180℃; im Rohr;

: 2280-44-6
D-Glucose

: 61-90-5
L-leucine

A: 290-37-9
1,4-pyrazine

B: 109-08-0
2-Methylpyrazine

C: 123-32-0
2,5-dimethyl-pyrazine

D: 5910-89-4
2,3-dimethylpyrazine

E: 108-50-9
2,6-dimethylpyrazine

F: 14667-55-1
2,3,5-trimethylpyrazine

G var. alkyl substituted pyrazines: var. alkyl substituted pyrazines

Conditions

Conditions	Yield
With ammonium hydroxide In glycerol at 120℃; for 4h; Product distribution; var. times, solvents, temp., and ratios of reactants, also without leucine;

...Expand

: 50-99-7
D-glucose

: 134276-45-2
H-Lys-Lys-OH hydrochloride

A: 290-37-9
1,4-pyrazine

B: 109-08-0
2-Methylpyrazine

C: 123-32-0
2,5-dimethyl-pyrazine

D: 5910-89-4
2,3-dimethylpyrazine

E: 13360-65-1
2-ethyl-3,6-dimethylpyrazine

F: 108-50-9
2,6-dimethylpyrazine

G: 14667-55-1
2,3,5-trimethylpyrazine

H: 80935-98-4
3-ethenyl-2,5-dimethylpyrazine

I: 13925-03-6
2-ethyl-6-methylpyrazine

Conditions

Conditions	Yield
In water at 130℃; for 2h; pH=8; Maillard reaction;

...Expand

: 134276-45-2
H-Lys-Lys-OH hydrochloride

: 78-98-8
2-oxopropanal

A: 109-08-0
2-Methylpyrazine

B: 123-32-0
2,5-dimethyl-pyrazine

C: 5910-89-4
2,3-dimethylpyrazine

D: 13360-65-1
2-ethyl-3,6-dimethylpyrazine

E: 108-50-9
2,6-dimethylpyrazine

F: 55138-74-4
3,5-dimethyl-2-(Z-1-propenyl)-pyrazine

G: 14667-55-1
2,3,5-trimethylpyrazine

H: 80935-98-4
3-ethenyl-2,5-dimethylpyrazine

I: 13925-07-0
2-ethyl-3,5-dimethylpyrazine

J: 15707-34-3
2,3-dimethyl-5-ethylpyrazine

Conditions

Conditions	Yield
In water at 130℃; for 2h; pH=8; Maillard reaction;

...Expand

: 50-99-7
D-glucose

: 410538-35-1
LysAla*hydrobromide

A: 290-37-9
1,4-pyrazine

B: 109-08-0
2-Methylpyrazine

C: 123-32-0
2,5-dimethyl-pyrazine

D: 5910-89-4
2,3-dimethylpyrazine

E: 13360-65-1
2-ethyl-3,6-dimethylpyrazine

F: 108-50-9
2,6-dimethylpyrazine

G: 14667-55-1
2,3,5-trimethylpyrazine

H: 13925-03-6
2-ethyl-6-methylpyrazine

I: 13360-64-0
2-ethyl-5-methypyrazine

J: 15707-34-3
2,3-dimethyl-5-ethylpyrazine

Conditions

Conditions	Yield
In water at 130℃; for 2h; pH=8; Maillard reaction;

...Expand

: 410538-35-1
LysAla*hydrobromide

: 78-98-8
2-oxopropanal

A: 109-08-0
2-Methylpyrazine

B: 123-32-0
2,5-dimethyl-pyrazine

C: 5910-89-4
2,3-dimethylpyrazine

D: 1124-11-4
Tetramethylpyrazine

E: 13360-65-1
2-ethyl-3,6-dimethylpyrazine

F: 108-50-9
2,6-dimethylpyrazine

G: 14667-55-1
2,3,5-trimethylpyrazine

H: 80935-98-4
3-ethenyl-2,5-dimethylpyrazine

I: 13925-07-0
2-ethyl-3,5-dimethylpyrazine

J: 15707-34-3
2,3-dimethyl-5-ethylpyrazine

Conditions

Conditions	Yield
In water at 130℃; for 2h; pH=8; Maillard reaction;

...Expand

: 50-99-7
D-glucose

: 103404-72-4
LysLeu*acetate

A: 290-37-9
1,4-pyrazine

B: 109-08-0
2-Methylpyrazine

C: 123-32-0
2,5-dimethyl-pyrazine

D: 5910-89-4
2,3-dimethylpyrazine

E: 13360-65-1
2-ethyl-3,6-dimethylpyrazine

F: 108-50-9
2,6-dimethylpyrazine

G: 14667-55-1
2,3,5-trimethylpyrazine

H: 13925-03-6
2-ethyl-6-methylpyrazine

I: 13925-07-0
2-ethyl-3,5-dimethylpyrazine

J: 13360-64-0
2-ethyl-5-methypyrazine

Conditions

Conditions	Yield
In water at 130℃; for 2h; pH=8; Maillard reaction;

...Expand

: 103404-72-4
LysLeu*acetate

: 78-98-8
2-oxopropanal

A: 109-08-0
2-Methylpyrazine

B: 123-32-0
2,5-dimethyl-pyrazine

C: 5910-89-4
2,3-dimethylpyrazine

D: 13360-65-1
2-ethyl-3,6-dimethylpyrazine

E: 108-50-9
2,6-dimethylpyrazine

F: 14667-55-1
2,3,5-trimethylpyrazine

G: 17398-16-2
2,3,5-trimethyl-6-ethylpyrazine

H: 13925-07-0
2-ethyl-3,5-dimethylpyrazine

I: 15707-34-3
2,3-dimethyl-5-ethylpyrazine

J: 18433-97-1
2,5-dimethyl-3-propylpyrazine

Conditions

Conditions	Yield
In water at 130℃; for 2h; pH=8; Maillard reaction;

...Expand

: 50-99-7
D-glucose

: 275366-32-0
LysSer*hydrochloride

A: 290-37-9
1,4-pyrazine

B: 109-08-0
2-Methylpyrazine

C: 123-32-0
2,5-dimethyl-pyrazine

D: 5910-89-4
2,3-dimethylpyrazine

E: 13360-65-1
2-ethyl-3,6-dimethylpyrazine

F: 108-50-9
2,6-dimethylpyrazine

G: 14667-55-1
2,3,5-trimethylpyrazine

H: 13925-03-6
2-ethyl-6-methylpyrazine

I: 13925-07-0
2-ethyl-3,5-dimethylpyrazine

J: 13360-64-0
2-ethyl-5-methypyrazine

Conditions

Conditions	Yield
In water at 130℃; for 2h; pH=8; Maillard reaction;

...Expand

: 275366-32-0
LysSer*hydrochloride

: 78-98-8
2-oxopropanal

A: 109-08-0
2-Methylpyrazine

B: 123-32-0
2,5-dimethyl-pyrazine

C: 5910-89-4
2,3-dimethylpyrazine

D: 13360-65-1
2-ethyl-3,6-dimethylpyrazine

E: 108-50-9
2,6-dimethylpyrazine

F: 14667-55-1
2,3,5-trimethylpyrazine

G: 80935-98-4
3-ethenyl-2,5-dimethylpyrazine

H: 13925-07-0
2-ethyl-3,5-dimethylpyrazine

I: 22047-27-4
1-(5-methylpyrazin-2-yl)ethanone

J: 15707-34-3
2,3-dimethyl-5-ethylpyrazine

Conditions

Conditions	Yield
In water at 130℃; for 2h; pH=8; Maillard reaction;

...Expand

: 50-99-7
D-glucose

: 106325-92-2
Lys-Cys

A: 290-37-9
1,4-pyrazine

B: 109-08-0
2-Methylpyrazine

C: 123-32-0
2,5-dimethyl-pyrazine

D: 5910-89-4
2,3-dimethylpyrazine

E: 13360-65-1
2-ethyl-3,6-dimethylpyrazine

F: 108-50-9
2,6-dimethylpyrazine

G: 14667-55-1
2,3,5-trimethylpyrazine

H: 13925-03-6
2-ethyl-6-methylpyrazine

I: 13360-64-0
2-ethyl-5-methypyrazine

J: 15707-34-3
2,3-dimethyl-5-ethylpyrazine

Conditions

Conditions	Yield
In water at 130℃; for 2h; pH=8; Maillard reaction;

...Expand

: 106325-92-2
Lys-Cys

: 78-98-8
2-oxopropanal

A: 123-32-0
2,5-dimethyl-pyrazine

B: 5910-89-4
2,3-dimethylpyrazine

C: 13360-65-1
2-ethyl-3,6-dimethylpyrazine

D: 108-50-9
2,6-dimethylpyrazine

E: 14667-55-1
2,3,5-trimethylpyrazine

F: 17398-16-2
2,3,5-trimethyl-6-ethylpyrazine

G: 13925-07-0
2-ethyl-3,5-dimethylpyrazine

H: 22047-26-3
1-(6-methyl-2-pyrazinyl)-1-ethanone

I: 22047-27-4
1-(5-methylpyrazin-2-yl)ethanone

J: 15707-34-3
2,3-dimethyl-5-ethylpyrazine

Conditions

Conditions	Yield
In water at 130℃; for 2h; pH=8; Maillard reaction;

...Expand

: 56-41-7
L-alanin

: 56-87-1
L-lysine

: 50-99-7
D-glucose

A: 290-37-9
1,4-pyrazine

B: 109-08-0
2-Methylpyrazine

C: 123-32-0
2,5-dimethyl-pyrazine

D: 5910-89-4
2,3-dimethylpyrazine

E: 13360-65-1
2-ethyl-3,6-dimethylpyrazine

F: 108-50-9
2,6-dimethylpyrazine

G: 14667-55-1
2,3,5-trimethylpyrazine

H: 80935-98-4
3-ethenyl-2,5-dimethylpyrazine

I: 13925-03-6
2-ethyl-6-methylpyrazine

J: 13360-64-0
2-ethyl-5-methypyrazine

Conditions

Conditions	Yield
In water at 130℃; for 2h; pH=8; Maillard reaction;

...Expand

: 56-41-7
L-alanin

: 56-87-1
L-lysine

: 78-98-8
2-oxopropanal

A: 109-08-0
2-Methylpyrazine

B: 123-32-0
2,5-dimethyl-pyrazine

C: 5910-89-4
2,3-dimethylpyrazine

D: 13360-65-1
2-ethyl-3,6-dimethylpyrazine

E: 108-50-9
2,6-dimethylpyrazine

F: 14667-55-1
2,3,5-trimethylpyrazine

G: 80935-98-4
3-ethenyl-2,5-dimethylpyrazine

H: 13925-07-0
2-ethyl-3,5-dimethylpyrazine

I: 22047-26-3
1-(6-methyl-2-pyrazinyl)-1-ethanone

J: 15707-34-3
2,3-dimethyl-5-ethylpyrazine

Conditions

Conditions	Yield
In water at 130℃; for 2h; pH=8; Maillard reaction;

...Expand

: 56-45-1
L-serin

: 56-87-1
L-lysine

: 50-99-7
D-glucose

A: 290-37-9
1,4-pyrazine

B: 109-08-0
2-Methylpyrazine

C: 123-32-0
2,5-dimethyl-pyrazine

D: 5910-89-4
2,3-dimethylpyrazine

E: 22047-25-2
acetylpyrazine

F: 13360-65-1
2-ethyl-3,6-dimethylpyrazine

G: 108-50-9
2,6-dimethylpyrazine

H: 14667-55-1
2,3,5-trimethylpyrazine

I: 13925-03-6
2-ethyl-6-methylpyrazine

J: 13360-64-0
2-ethyl-5-methypyrazine

Conditions

Conditions	Yield
In water at 130℃; for 2h; pH=8; Maillard reaction;

...Expand

: 56-45-1
L-serin

: 56-87-1
L-lysine

: 78-98-8
2-oxopropanal

A: 290-37-9
1,4-pyrazine

B: 109-08-0
2-Methylpyrazine

C: 123-32-0
2,5-dimethyl-pyrazine

D: 5910-89-4
2,3-dimethylpyrazine

E: 13360-65-1
2-ethyl-3,6-dimethylpyrazine

F: 108-50-9
2,6-dimethylpyrazine

G: 14667-55-1
2,3,5-trimethylpyrazine

H: 80935-98-4
3-ethenyl-2,5-dimethylpyrazine

I: 22047-27-4
1-(5-methylpyrazin-2-yl)ethanone

J: 15707-34-3
2,3-dimethyl-5-ethylpyrazine

Conditions

Conditions	Yield
In water at 130℃; for 2h; pH=8; Maillard reaction;

...Expand

: 52-90-4
L-Cysteine

: 56-87-1
L-lysine

: 50-99-7
D-glucose

A: 290-37-9
1,4-pyrazine

B: 109-08-0
2-Methylpyrazine

C: 5910-89-4
2,3-dimethylpyrazine

D: 14667-55-1
2,3,5-trimethylpyrazine

E: 13925-03-6
2-ethyl-6-methylpyrazine

F: 15707-34-3
2,3-dimethyl-5-ethylpyrazine

Conditions

Conditions	Yield
In water at 130℃; for 2h; pH=8; Maillard reaction;

...Expand

: 61-90-5
L-leucine

: 56-87-1
L-lysine

: 50-99-7
D-glucose

A: 290-37-9
1,4-pyrazine

B: 109-08-0
2-Methylpyrazine

C: 123-32-0
2,5-dimethyl-pyrazine

D: 5910-89-4
2,3-dimethylpyrazine

E: 1124-11-4
Tetramethylpyrazine

F: 13360-65-1
2-ethyl-3,6-dimethylpyrazine

G: 108-50-9
2,6-dimethylpyrazine

H: 14667-55-1
2,3,5-trimethylpyrazine

I: 13925-03-6
2-ethyl-6-methylpyrazine

J: 13360-64-0
2-ethyl-5-methypyrazine

Conditions

Conditions	Yield
In water at 130℃; for 2h; pH=8; Maillard reaction;

...Expand

: 61-90-5
L-leucine

: 56-87-1
L-lysine

: 78-98-8
2-oxopropanal

A: 109-08-0
2-Methylpyrazine

B: 123-32-0
2,5-dimethyl-pyrazine

C: 5910-89-4
2,3-dimethylpyrazine

D: 1124-11-4
Tetramethylpyrazine

E: 13360-65-1
2-ethyl-3,6-dimethylpyrazine

F: 108-50-9
2,6-dimethylpyrazine

G: 55138-72-2
2,3-dimethyl-5-(Z-1-propenyl)-pyrazine

H: 14667-55-1
2,3,5-trimethylpyrazine

I: 13925-07-0
2-ethyl-3,5-dimethylpyrazine

Conditions

Conditions	Yield
In water at 130℃; for 2h; pH=8; Maillard reaction;

...Expand

: 56-87-1
L-lysine

: 56-86-0
L-glutamic acid

: 50-99-7
D-glucose

A: 290-37-9
1,4-pyrazine

B: 109-08-0
2-Methylpyrazine

C: 123-32-0
2,5-dimethyl-pyrazine

D: 5910-89-4
2,3-dimethylpyrazine

E: 13360-65-1
2-ethyl-3,6-dimethylpyrazine

F: 108-50-9
2,6-dimethylpyrazine

G: 14667-55-1
2,3,5-trimethylpyrazine

H: 13925-03-6
2-ethyl-6-methylpyrazine

I: 13925-07-0
2-ethyl-3,5-dimethylpyrazine

J: 13360-64-0
2-ethyl-5-methypyrazine

Conditions

Conditions	Yield
In water at 130℃; for 2h; pH=8; Maillard reaction;

...Expand

: 56-87-1
L-lysine

: 56-86-0
L-glutamic acid

: 78-98-8
2-oxopropanal

A: 123-32-0
2,5-dimethyl-pyrazine

B: 5910-89-4
2,3-dimethylpyrazine

C: 108-50-9
2,6-dimethylpyrazine

D: 55138-72-2
2,3-dimethyl-5-(Z-1-propenyl)-pyrazine

E: 55138-74-4
3,5-dimethyl-2-(Z-1-propenyl)-pyrazine

F: 14667-55-1
2,3,5-trimethylpyrazine

G: 17398-16-2
2,3,5-trimethyl-6-ethylpyrazine

H: 22047-27-4
1-(5-methylpyrazin-2-yl)ethanone

I: 15707-34-3
2,3-dimethyl-5-ethylpyrazine

J: 18433-97-1
2,5-dimethyl-3-propylpyrazine

Conditions

Conditions	Yield
In water at 130℃; for 2h; pH=8; Maillard reaction;

...Expand

: 56-87-1
L-lysine

: 50-99-7
D-glucose

A: 290-37-9
1,4-pyrazine

B: 109-08-0
2-Methylpyrazine

C: 123-32-0
2,5-dimethyl-pyrazine

D: 5910-89-4
2,3-dimethylpyrazine

E: 22047-25-2
acetylpyrazine

F: 13360-65-1
2-ethyl-3,6-dimethylpyrazine

G: 108-50-9
2,6-dimethylpyrazine

H: 14667-55-1
2,3,5-trimethylpyrazine

I: 13925-07-0
2-ethyl-3,5-dimethylpyrazine

J: 13360-64-0
2-ethyl-5-methypyrazine

Conditions

Conditions	Yield
In water at 130℃; for 2h; pH=8; Maillard reaction;

...Expand

: 56-87-1
L-lysine

: 50-99-7
D-glucose

A: 290-37-9
1,4-pyrazine

B: 109-08-0
2-Methylpyrazine

C: 123-32-0
2,5-dimethyl-pyrazine

D: 5910-89-4
2,3-dimethylpyrazine

E: 108-50-9
2,6-dimethylpyrazine

F: 14667-55-1
2,3,5-trimethylpyrazine

G: 80935-98-4
3-ethenyl-2,5-dimethylpyrazine

H: 13925-03-6
2-ethyl-6-methylpyrazine

Conditions

Conditions	Yield
In water at 130℃; for 2h; pH=8; Maillard reaction;

...Expand

: 5910-89-4
2,3-dimethylpyrazine

: 73183-34-3
bis(pinacol)diborane

: 2,3-dimethyl-1,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,4-dihydropyrazine

Conditions

Conditions	Yield
With pyridine-4-carbonitrile In benzene-d6 at 20℃; for 12h; Kinetics; Mechanism; Reagent/catalyst; Solvent; Temperature; Time; Inert atmosphere; Schlenk technique;	100%
With 2,6-dichloro-4,4’-bipyridine In cyclohexane at 60℃; for 16h; Reagent/catalyst; Solvent; Temperature; Glovebox; Inert atmosphere;	84%
In pentane N2; ligand and B compd. (1.1:1 molar ratio) stirred at room temp. for 2 h;	0%

: 5910-89-4
2,3-dimethylpyrazine

: 617-86-7
triethylsilane

: 2-triethylsilyl-4,5-dimethylpyrazine

Conditions

Conditions	Yield
With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 3,4,7,8-Tetramethyl-o-phenanthrolin; norbornene In di-isopropyl ether at 100℃; for 48h; Inert atmosphere; Glovebox;	97%

: 5910-89-4
2,3-dimethylpyrazine

: copper(II) perchlorate hexahydrate

: 540-72-7
sodium thiocyanide

: 2,3-dimethylpyrazinobisthiocyanatodicopper(I)

Conditions

Conditions	Yield
In water addn. of an aq. soln. of Cu(ClO4)2*6H2O to an aq. soln. of 2,3-dimethylpyrazine, addn. of an aq. soln. of NaSCN to the mixt. and stirring; filtration of the yellow solid and washing with water and acetone;	91%

...Expand

: 5910-89-4
2,3-dimethylpyrazine

: dichloro-bis(triethylphosphine)-di-μ-chloro-diplatinum(II)

: 118515-83-6
trans-{PtCl2(triethylphosphine)}2(2,3-dimethylpyrazine)

Conditions

Conditions	Yield
In chloroform-d1 ligand and Pt complex (1:2 mol) in CDCl3 (or CD2Cl2) were stirred for 5 min; floating layer of hexane over soln.; elem. anal.;	90%

: 5910-89-4
2,3-dimethylpyrazine

: 65464-21-3
2,3-dimethyl-1,4-diazine N-oxide

Conditions

Conditions	Yield
With 3-chloro-benzenecarboperoxoic acid In dichloromethane for 16h;	88%
With dihydrogen peroxide; methyltrioxorhenium(VII) In dichloromethane at 20℃;	85%
With sodium perborate; acetic acid at 80℃; for 5h;	47%

: 5910-89-4
2,3-dimethylpyrazine

: 89-01-0
2,3-dicarboxypyrazine

: silver nitrate

: [Ag2(Hpyzdc)2(μ-dmpyz)]

Conditions

Conditions	Yield
With sodium hydroxide In water pH=7;	88%

...Expand

: 5910-89-4
2,3-dimethylpyrazine

: 38870-37-0
2,3-dimethylpyrazine-N,N'-dioxide

Conditions

Conditions	Yield
With Oxone In dichloromethane at 25℃; for 24h;	87.7%

: 5910-89-4
2,3-dimethylpyrazine

: 7787-70-4
copper(I) bromide

: 336881-20-0
poly[μ2-bromo-μ2-2,3-dimethylpyrazine-N,N'-copper(I)]

Conditions

Conditions	Yield
In acetonitrile CuBr and 2,3-dimethylpyrazine (3-fold excess) in MeCN stirred at room temp. for 1 d; ppt. filtered off, washed with Et2O; elem. anal.;	86.5%
In acetonitrile CuBr and 2,3-dimethylpyrazine (1:1.1 mol) in MeCN were mixed; filtered off after 2 d; washed (EtOH, Et2O);

: 5910-89-4
2,3-dimethylpyrazine

: 16523-54-9
chlorodicyclohexylphosphane

: 2,3-bis((dicyclohexylphosphino)methyl)pyrazine

Conditions

Conditions	Yield
Stage #1: 2,3-dimethylpyrazine With n-butyllithium; N,N,N,N,-tetramethylethylenediamine In diethyl ether; hexane at -78 - 80℃; Inert atmosphere; Stage #2: chlorodicyclohexylphosphane In diethyl ether at -78 - 20℃; Inert atmosphere;	86%

: 5910-89-4
2,3-dimethylpyrazine

: copper(l) cyanide

: poly[(tri-μ2-cyano-C,N)-bis(μ2-2,3-dimethyl-pyrazine-N,N)]tricopper(I)

Conditions

Conditions	Yield
In acetonitrile CuCN and ligand stirred in MeCN at room temp. for 3 d or without stirring for 7 d; filtered, washed with EtOH and Et2O; elem. anal.;	85.3%

: 5910-89-4
2,3-dimethylpyrazine

: silver hexafluoroantimonate

: 2Ag(1+)*3C4H2N2(CH3)2*2SbF6(1-) = [Ag2(C4H2N2(CH3)2)3](SbF6)2

Conditions

Conditions	Yield
In ethanol; dichloromethane layering EtOH over a soln. of the ligand in CH2Cl2, then layering a soln. of the Ag salt in EtOH; crystn. with some d;	85%

: 5910-89-4
2,3-dimethylpyrazine

: dodecatungstosilic acid

: copper(II) nitrate trihydrate

: ([Cu(2,3-dimethylpyrazine)1.5]4(SiW12O40))n

Conditions

Conditions	Yield
With NaOH In water High Pressure; dissolving tungsten compd., pyrazine deriv. and copper compd. in distld.water at room temp., adjusting pH to 3-4 by 1 M NaOH, heating at 180.de gree.C for 34 h, cooling to 100°C at rate of 10 °C/h, heating at 100°C for 16 h; cooling to room temp. at rate of 3 °C/h, isolating crystals, elem. anal.;	85%

...Expand

: 5910-89-4
2,3-dimethylpyrazine

: 619-42-1
4-methoxycarbonylphenyl bromide

: (Z)-1-(4-bromophenyl)-2-(3-methylpyrazin-2-yl)ethen-1-ol

Conditions

Conditions	Yield
With sodium hydride In tetrahydrofuran; mineral oil at 60℃; for 16h;	84%

: 5910-89-4
2,3-dimethylpyrazine

: 636-46-4
4-hydroxyisophthalic acid

: 2C8H6O5*C6H8N2

Conditions

Conditions	Yield
In methanol at 20℃; for 336h;	84%

: 5910-89-4
2,3-dimethylpyrazine

: 358-23-6
trifluoromethylsulfonic anhydride

: 603-35-0
triphenylphosphine

: (5,6-dimethylpyrazin-2-yl)triphenylphosphonium trifluoromethanesulfonate

Conditions

Conditions	Yield
Stage #1: 2,3-dimethylpyrazine; trifluoromethylsulfonic anhydride In dichloromethane at -78℃; for 0.5h; Inert atmosphere; Stage #2: triphenylphosphine In dichloromethane at -78℃; for 0.5h; Inert atmosphere; Stage #3: With triethylamine In dichloromethane at -78 - 20℃; Inert atmosphere;	83%

...Expand

: 5910-89-4
2,3-dimethylpyrazine

: rhodium(II) benzoate

: [Rh2(benzoato)4(2,3-dimethylpyrazine)](n)

Conditions

Conditions	Yield
In acetonitrile a soln. of Rh complex allowed to stand at room temp. with a ligand vaporfor 1 mo; filtered, washed (MeOH), air-dried; elem. anal.;	82%

: 5910-89-4
2,3-dimethylpyrazine

: 1027513-97-8
2,2-difluoro-2-(4-methoxyphenyl)acetic acid

: 5-(difluoro(4-methoxyphenyl)methyl)-2,3-dimethylpyrazine

Conditions

Conditions	Yield
With ammonium peroxydisulfate; silver nitrate In dichloromethane; water at 50℃; for 24h; Minisci Aromatic Substitution; Inert atmosphere; Sealed tube; regioselective reaction;	81%

: 5910-89-4
2,3-dimethylpyrazine

: sodium azide

: manganese (II) nitrate tetrahydrate

: [Mn(N3)2(H2O)2](n)(2,3-dimethylpyrazine)(n)

Conditions

Conditions	Yield
In further solvent(s) Mn salt, NaN3 and 2,3-dimethylpyrazine dissolved in aq. hydrazoic acid; cooled slowly to 4°C for 3 d; elem. anal.;	80%

...Expand

: 5910-89-4
2,3-dimethylpyrazine

: 74-88-4
methyl iodide

: 91468-09-6
1,2,3-trimethylpyrazinium iodide

Conditions

Conditions	Yield
In ethanol	79.3%
for 2h; Heating;	63%

: 5910-89-4
2,3-dimethylpyrazine

: 84468-52-0
2,3-dimethylpiperazine

Conditions

Conditions	Yield
With palladium 10% on activated carbon; hydrogen In ethanol at 40℃; for 72h;	79.2%
With hydrogen; palladium 10% on activated carbon In ethanol under 2844.39 - 3102.97 Torr; for 72h;

: 5910-89-4
2,3-dimethylpyrazine

: 554-95-0
benzene-1,3,5-tricarboxylic acid

: 7732-18-5
water

: 20667-12-3
silver(l) oxide

: [Ag6(2,3-dimethylpyrazine)2(trimesic acid(-3H))2·5(water)]n

Conditions

Conditions	Yield
With ammonium hydroxide In N,N-dimethyl-formamide Sonication;	79%

...Expand

: 5910-89-4
2,3-dimethylpyrazine

: 69-72-7
salicylic acid

: C7H6O3*0.5C6H8N2

Conditions

Conditions	Yield
In water; acetone for 0.333333h;	79%

: 5910-89-4
2,3-dimethylpyrazine

: 81-05-0
6-aminonaphthalene-1-sulfonic acid

: 7732-18-5
water

: silver carbonate

: [Ag(6-amino-1-naphthalenesulfonato)(2,3-dimethylpyrazine)]*1.5H2O

Conditions

Conditions	Yield
With NH3 In water byproducts: CO2; Ag2CO3 added to an aq. soln. of 6-amino-1-naphthalenesulfonic acid, stirred, (CH3)2C4H2N2 added, stirred, an aq. soln. of NH3 added dropwise; crystd. at room temp.; elem. anal.;	78%

...Expand

: 5910-89-4
2,3-dimethylpyrazine

: 121-91-5
isophthalic acid

: 20667-12-3
silver(l) oxide

: [Ag4(2,3-dimethylpyrazine)2(m-phthalate)2]n

Conditions

Conditions	Yield
With ammonium hydroxide In ethanol; N,N-dimethyl-formamide Sonication;	78%

...Expand

: 5910-89-4
2,3-dimethylpyrazine

: 7681-65-4
copper(l) iodide

: 7681-11-0
potassium iodide

: 2D-CuI(2,3-dimethylpyrazine)0.5

Conditions

Conditions	Yield
In ethanol; acetonitrile at 20℃; for 72h;	78%

...Expand

: 123-91-1
1,4-dioxane

: 5910-89-4
2,3-dimethylpyrazine

: 5-(1,4-dioxan-2-yl)-2,3-dimethylpyrazine

Conditions

Conditions	Yield
With trifluorormethanesulfonic acid; dibenzoyl peroxide at 100℃; for 12h; Inert atmosphere;	77%
With trifluorormethanesulfonic acid; dibenzoyl peroxide at 100℃; for 12h; Inert atmosphere;	77%

: 5910-89-4
2,3-dimethylpyrazine

: 652-36-8
2,3,5,6-tetrafluoroterephthalic acid

: C8H2F4O4*C6H8N2

Conditions

Conditions	Yield
In methanol; water for 0.25h;	76%

: 5910-89-4
2,3-dimethylpyrazine

: 1079-66-9
chloro-diphenylphosphine

: 2,3-bis((diphenylphosphino)methyl)pyrazine

Conditions

Conditions	Yield
Stage #1: 2,3-dimethylpyrazine With n-butyllithium; N,N,N,N,-tetramethylethylenediamine In diethyl ether; hexane at -78 - 80℃; Inert atmosphere; Stage #2: chloro-diphenylphosphine In diethyl ether at -78 - 20℃; Inert atmosphere;	75%

: 5910-89-4
2,3-dimethylpyrazine

: 36016-40-7
mesitylenesulfonylhydroxylamine

: 139242-98-1
2,4,6-Trimethyl-benzenesulfonate1-amino-2,3-dimethyl-pyrazin-1-ium;

Conditions

Conditions	Yield
In dichloromethane for 0.166667h; Ambient temperature;	74%

2,3-DIMETHYLPYRAZINE Chemical Properties

Molecular Formula: C₆H₈N₂
Formula Weight: 108.14
mp of 2,3-DIMETHYLPYRAZINE (5910-89-4): 11-13 °C
bp of 2,3-DIMETHYLPYRAZINE (5910-89-4): 156 °C(lit.)
density : 1.02
refractive index : n20/D 1.507(lit.)
Fp of 2,3-DIMETHYLPYRAZINE (5910-89-4): 130 °F
storage temp. : Flammables area
PHYSICAL STATE: clear to pale yellow liquid

2,3-DIMETHYLPYRAZINE Uses

2,3-DIMETHYLPYRAZINE (5910-89-4) is used as a composition of flavouring, mainly for confecting essence of meat, nuts, chocolate, coffee, cream and tobacco.

2,3-DIMETHYLPYRAZINE Production

By heating the reaction product of diacetyl and quadrol with potassium hydroxide in the ethanol to form 2,3-DIMETHYLPYRAZINE (5910-89-4). 2,3-DIMETHYLPYRAZINE (5910-89-4) is also formed during the cooking of some foods via Maillard reactions.

2,3-DIMETHYLPYRAZINE Toxicity Data With Reference

1.		orl-rat LD50:613 mg/kg		DCTODJ Drug and Chemical Toxicology. 3 (1980),249.
2.		ipr-mus LD50:1390 mg/kg		TXAPA9 Toxicology and Applied Pharmacology. 17 (1970),244.

2,3-DIMETHYLPYRAZINE Consensus Reports

Reported in EPA TSCA Inventory.

2,3-DIMETHYLPYRAZINE Safety Profile

Hazard Codes : Xn,F,Xi (Harmful; Highly Flammable; Irritant)
Risk Statements : 10-22-37/38-41 (Flammable; Harmful if swallowed; Irritating to respiratory system and skin; Risk of serious damage to eyes)
Safety Statements : 16-26-39 (Keep away from sources of ignition - No smoking; In case of contact with eyes, rinse immediately with plenty of water and seek medical advice; Wear eye/face protection)
RIDADR : UN 1993 3/PG 3
WGK Germany : 3
RTECS : UQ2625000
Hazard Note : Irritant/Flammable
HazardClass : 3
PackingGroup : III
HS Code : 29339990
Moderately toxic by ingestion and intraperitoneal routes. Flammable liquid when exposed to heat, sparks, or flame. When heated to decomposition it emits toxic fumes of NO_x.

2,3-DIMETHYLPYRAZINE Standards and Recommendations

ASSAY (G.C): 98.0% min

Product Name

2,3-Dimethylpyrazine

Synthetic route

2,3-DIMETHYLPYRAZINE Chemical Properties

2,3-DIMETHYLPYRAZINE Uses

2,3-DIMETHYLPYRAZINE Production

2,3-DIMETHYLPYRAZINE Toxicity Data With Reference

2,3-DIMETHYLPYRAZINE Consensus Reports

2,3-DIMETHYLPYRAZINE Safety Profile

2,3-DIMETHYLPYRAZINE Standards and Recommendations

Related Products

Hot Products