2,6-Dichloro-4-nitroaniline supplier

Name
2,6-Dichloro-4-nitroaniline
EINECS 202-746-4
CAS No. 99-30-9
Article Data53
CAS DataBase
Density 1.624 g/cm³
Solubility 1 g/L in water at 60 °C
Melting Point 190-192 °C(lit.)
Formula C₆H₄Cl₂N₂O₂
Boiling Point 323 °C at 760 mmHg
Molecular Weight 207.016
Flash Point 149.1 °C
Transport Information UN 2811
Appearance yellow granular powder and chunks
Safety 22-26-36-37/39
Risk Codes 33-36/37/38-20/21/22
Molecular Structure
Hazard Symbols Xi,Xn
Synonyms Aniline,2,6-dichloro-4-nitro- (6CI,8CI);1-Amino-2,6-dichloro-4-nitrobenzene;2,6-Dichloro-4-nitrobenzenamine;2,6-Dichloro-p-nitroaniline;4-Nitro-2,6-dichloroaniline;AL 50;Allisan;Batran;Bortran;Botran;Botran 75B;Botran 75W;CNA;DCNA;Ditranil;NSC 218;U-2069;
PSA 71.84000
LogP 3.58820

Synthetic route

: 100-01-6
4-nitro-aniline

: 99-30-9
4-nitro-2,6-dichloroaniline

Conditions

Conditions	Yield
With hydrogenchloride; dihydrogen peroxide In water at -8 - 20℃; for 2h; Temperature; Reagent/catalyst;	99.5%
With N-chloro-N-(benzenesulfonyl)benzenesulfonamide In acetonitrile at 20 - 25℃; for 0.133333h; Green chemistry;	99%
Stage #1: 4-nitro-aniline With hydrogenchloride In water at 63℃; for 0.5h; Stage #2: With chlorine In water for 0.166667h; Temperature; Time;	98.65%

: 609-20-1
2,6-dichloro-p-phenylenediamine

: 99-30-9
4-nitro-2,6-dichloroaniline

Conditions

Conditions	Yield
With 1,9-diperoxynonanedioic acid In acetonitrile at 50℃; for 0.5h;	92%

: 59992-52-8
2,6-dichloro-4-aminonitrobenzene

: 99-30-9
4-nitro-2,6-dichloroaniline

Conditions

Conditions	Yield
With nickel(II) tetrafluoroborate hexahydrate; ammonia; hydrogen; bis(2-diphenylphosphinoethyl)phenylphosphine In 2,2,2-trifluoroethanol at 120℃; under 37503.8 Torr; for 24h; chemoselective reaction;	90%

: 100-01-6
4-nitro-aniline

A: 99-30-9
4-nitro-2,6-dichloroaniline

B: 121-87-9
2-Chloro-4-nitroaniline

Conditions

Conditions	Yield
With N-chloro-N-(benzenesulfonyl)benzenesulfonamide In 1,4-dioxane at 20 - 25℃; Solvent; Green chemistry;	A n/a B 50%
With hydrogenchloride; sodium chlorate In water; acetic acid at 20℃; for 40h;	A 9% B 32%
Chlorierung;
With methanol; chlorine

: 22134-75-4
4-amino-3,5-dichloro-benzenesulfonamide

: 99-30-9
4-nitro-2,6-dichloroaniline

Conditions

Conditions	Yield
With ammonium nitrate; sulfuric acid at 0 - 5℃; for 0.25h;	21%

: 100-01-6
4-nitro-aniline

A: 99-30-9
4-nitro-2,6-dichloroaniline

B: 121-87-9
2-Chloro-4-nitroaniline

C: 3646-57-9, 89103-79-7
bis(4-nitrophenyl)diazene

Conditions

Conditions	Yield
With sodium hydroxide; sodium hypochlorite In ethanol at 25℃; for 0.0833333h;	A n/a B 15% C 9%

...Expand

: 60-29-7
diethyl ether

: 408326-80-7
N,N-dichloro-4-nitro-aniline

: 99-30-9
4-nitro-2,6-dichloroaniline

: 697-88-1
4-bromo-2,6-dichloroaniline

: 99-30-9
4-nitro-2,6-dichloroaniline

Conditions

Conditions	Yield
With nitric acid; acetic acid

: 13633-34-6
1,3-dichloro-2,5-dinitro-benzene

: 99-30-9
4-nitro-2,6-dichloroaniline

Conditions

Conditions	Yield
With ethanol; ammonia in der Kaelte;

: 408326-80-7
N,N-dichloro-4-nitro-aniline

: 99-30-9
4-nitro-2,6-dichloroaniline

Conditions

Conditions	Yield
With hydrogenchloride; diethyl ether
With diethyl ether
With acetic anhydride

: 408326-80-7
N,N-dichloro-4-nitro-aniline

: 108-24-7
acetic anhydride

: 99-30-9
4-nitro-2,6-dichloroaniline

: 507-40-4
tert-butylhypochlorite

: 100-01-6
4-nitro-aniline

: 99-30-9
4-nitro-2,6-dichloroaniline

Conditions

Conditions	Yield
With benzene
With acetic acid
With tert-butyl alcohol

: 112160-74-4
acetic acid-(2,4,N-trichloro-anilide)

: 121-87-9
2-Chloro-4-nitroaniline

: 99-30-9
4-nitro-2,6-dichloroaniline

Conditions

Conditions	Yield
With chloroform

: 121-87-9
2-Chloro-4-nitroaniline

: 99-30-9
4-nitro-2,6-dichloroaniline

Conditions

Conditions	Yield
With hydrogenchloride; chlorine
With hydrogenchloride; dihydrogen peroxide In water at 30 - 40℃; Green chemistry;

: 54381-76-9
2,6-dichloro-N-nitroaniline

: 99-30-9
4-nitro-2,6-dichloroaniline

Conditions

Conditions	Yield
With trifluoroacetic acid-d1 In chloroform-d1 at 30℃; Rate constant; Mechanism; kinetic isotope effect;

: 7647-01-0
hydrogenchloride

: 7782-50-5
chlorine

: 121-87-9
2-Chloro-4-nitroaniline

: 99-30-9
4-nitro-2,6-dichloroaniline

...Expand

: 100-01-6
4-nitro-aniline

: 71-43-2
benzene

aqueous sodium hypochlorite: aqueous sodium hypochlorite

A: 99-30-9
4-nitro-2,6-dichloroaniline

B: bis-(2,6-dichloro-4-nitro-phenyl)-diazene-N-oxide

Conditions

Conditions	Yield
bei 2.5-stdg. Behandeln;

...Expand

: 7647-01-0
hydrogenchloride

: 100-01-6
4-nitro-aniline

potassium chlorate: potassium chlorate

A: 99-30-9
4-nitro-2,6-dichloroaniline

B: 121-87-9
2-Chloro-4-nitroaniline

...Expand

: 7647-01-0
hydrogenchloride

: 64-17-5
ethanol

: 7722-84-1
dihydrogen peroxide

: 100-01-6
4-nitro-aniline

A: 99-30-9
4-nitro-2,6-dichloroaniline

B: 3646-57-9, 89103-79-7
bis(4-nitrophenyl)diazene

...Expand

: 71756-91-7
4-bromo-2,6-dichloro-N-nitro-aniline

: 7664-93-9
sulfuric acid

: 64-19-7
acetic acid

: 99-30-9
4-nitro-2,6-dichloroaniline

...Expand

: 13633-34-6
1,3-dichloro-2,5-dinitro-benzene

: 7664-41-7
ammonia

: 99-30-9
4-nitro-2,6-dichloroaniline

: 7647-01-0
hydrogenchloride

: 60-29-7
diethyl ether

: 408326-80-7
N,N-dichloro-4-nitro-aniline

: 99-30-9
4-nitro-2,6-dichloroaniline

Conditions

Conditions	Yield
at -20℃;

...Expand

: 408326-80-7
N,N-dichloro-4-nitro-aniline

petroleum ether: petroleum ether

A: 99-30-9
4-nitro-2,6-dichloroaniline

B: 3646-57-9, 89103-79-7
bis(4-nitrophenyl)diazene

...Expand

: 71756-89-3
2,4,6-trichloro-N-nitroaniline

A: 99-30-9
4-nitro-2,6-dichloroaniline

B: 634-93-5
2,4,6-trichloroaniline

Conditions

Conditions	Yield
With silica gel at 140℃; for 2h; Product distribution; Further Variations:; Reagents;	A n/a B 20 % Chromat.

: 106-40-1
4-bromo-aniline

: 99-30-9
4-nitro-2,6-dichloroaniline

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: chloroform 2: glacial acetic acid; nitric acid View Scheme

: 1817-73-8
2-bromo-4,6-dinitroaniline

: 99-30-9
4-nitro-2,6-dichloroaniline

: 608-31-1
2,6-Dichloroaniline

: 99-30-9
4-nitro-2,6-dichloroaniline

Conditions

Conditions	Yield
With sulfuric acid; nitric acid Heating;

: 95-50-1
1,2-dichloro-benzene

: 99-30-9
4-nitro-2,6-dichloroaniline

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: sulfuric acid; nitric acid / 0 - 5 °C / Green chemistry 2: ammonia / water / Autoclave; Heating; Green chemistry 3: hydrogenchloride; dihydrogen peroxide / water / 30 - 40 °C / Green chemistry View Scheme

: 99-30-9
4-nitro-2,6-dichloroaniline

: 20098-48-0
3,4,5-trichloronitrobenzen

Conditions

Conditions	Yield
Stage #1: 4-nitro-2,6-dichloroaniline With sulfuric acid; sodium nitrite at 50 - 70℃; for 1h; Stage #2: With acetic acid at 5℃; for 1h; Stage #3: With hydrogenchloride; copper(l) chloride In water at 15 - 70℃; for 2h;	98.5%
Stage #1: 4-nitro-2,6-dichloroaniline With sulfuric acid; sodium nitrite at 5 - 70℃; for 0.333333h; Stage #2: With acetic acid for 0.5h; Stage #3: With hydrogenchloride; copper(l) chloride In water at 25 - 70℃; for 1h;	75%
With copper(I) chloride; hydrogenchloride; sulfuric acid In acetic acid for 1h;	47%
With methyl nitrite; sulfuric acid; acetic acid Diazotization.Behandeln mit Kupfer(I)-chlorid in konz. Salzsaeure;
Stage #1: 4-nitro-2,6-dichloroaniline With sulfuric acid; sodium nitrite at 50℃; for 0.666667h; Sandmeyer Reaction; Stage #2: With acetic acid at 5℃; for 1h; Sandmeyer Reaction; Stage #3: With hydrogenchloride; copper(l) chloride at 15 - 70℃; for 1.83333h; Sandmeyer Reaction;

: 99-30-9
4-nitro-2,6-dichloroaniline

: 98137-94-1
1-bromo-2,6-dichloro-4-nitrobenzene

Conditions

Conditions	Yield
With tert.-butylnitrite; copper(I) bromide In acetonitrile at 20℃; for 6h; Cooling with ice;	97%
With tert.-butylnitrite; copper(ll) bromide In acetonitrile at 20℃; for 10h; Cooling with ice;	92%
With hydrogen bromide; acetic acid; sodium nitrite

: 99-30-9
4-nitro-2,6-dichloroaniline

: 598-21-0
2-Bromoacetyl bromide

: 2-bromo-N-(2,6-dichloro-4-nitrophenyl)acetamide

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 20 - 60℃;	94%

: 99-30-9
4-nitro-2,6-dichloroaniline

: 22654-78-0, 99664-53-6
nitratocarbonylbis(triphenylphosphine)rhodium

: RhCO(P(C6H5)3)2HNC6H2Cl2NO2

Conditions

Conditions	Yield
With KOH In methanol; acetone to an acetone soln. of Rh complex were added equimolar quantity of nitroaniline (in acetone) and KOH in MeOH; solvents were evpd. in vac., red residue extd. with benzene and filtered from KNO3; solvent removed in vac., crystals pptd. with hexane, filtered, washed with hexane and dried in air; elem. anal.;	92%

: 99-30-9
4-nitro-2,6-dichloroaniline

: 1378039-78-1
4-azido-5-fluoro-pyridine-3-carbaldehyde

: 1378040-29-9
[1-(4-azido-5-fluoropyridin-3-yl)-meth-(E)-ylidene]-(2,6-dichloro-4-nitrophenyl)-amine

Conditions

Conditions	Yield
With titanium tetrachloride; triethylamine In dichloromethane at 0 - 20℃; for 4h; Inert atmosphere;	92%

: 99-30-9
4-nitro-2,6-dichloroaniline

: 108-95-2
phenol

: C12H7Cl2N3O3

Conditions

Conditions	Yield
Stage #1: 4-nitro-2,6-dichloroaniline With sulfuric acid; sodium nitrite In 1,2-dimethoxyethane; water at 0 - 5℃; for 1.25h; Stage #2: phenol With sodium carbonate In water at 0 - 70℃; for 7h; pH=9 - 10;	84.5%

: 99-30-9
4-nitro-2,6-dichloroaniline

: 131-57-7
Benzophenone-3

: 1243203-32-8
1-[2-hydroxy-4-methoxy-5-(2,6-dichloro-4-nitrophenylazo)phenyl]-1-phenylmethanone

Conditions

Conditions	Yield
Stage #1: 4-nitro-2,6-dichloroaniline With hydrogenchloride; sodium nitrite In water at 0 - 5℃; Stage #2: Benzophenone-3 In water at 0 - 20℃; Alkaline conditions;	84%

: 99-30-9
4-nitro-2,6-dichloroaniline

: N-cyclohexyl-2-(phenylamino)-2-(p-tolyl)acetamide

: (E)-N-cyclohexyl-2-((4-((2,6-dichloro-4-nitrophenyl)diazenyl)phenyl)amino)-2-(p-tolyl)acetamide

Conditions

Conditions	Yield
Stage #1: 4-nitro-2,6-dichloroaniline With hydrogenchloride In water at 40 - 60℃; for 2h; Stage #2: With sodium nitrite In water at 0℃; for 2h; Stage #3: N-cyclohexyl-2-(phenylamino)-2-(p-tolyl)acetamide With acetic acid In methanol; water at 0 - 20℃; for 24h;	84%

: 696-59-3
cis,trans-2,5-dimethoxytetrahydrofuran

: 99-30-9
4-nitro-2,6-dichloroaniline

: 93516-62-2
N-(2,6-dichloro-4-nitrophenyl)pyrrole

Conditions

Conditions	Yield
With acetic acid Heating;	82%

: 99-30-9
4-nitro-2,6-dichloroaniline

: 1383479-59-1
2-(2-bromophenyl)-N-cyclohexyl-2-(phenylamino)acetamide

: (E)-2-(2-bromophenyl)-N-cyclohexyl-2-((4-((2,6-dichloro-4-nitrophenyl)diazenyl)phenyl)amino)acetamide

Conditions

Conditions	Yield
Stage #1: 4-nitro-2,6-dichloroaniline With hydrogenchloride In water at 40 - 60℃; for 2h; Stage #2: With sodium nitrite In water at 0℃; for 2h; Stage #3: 2-(2-bromophenyl)-N-cyclohexyl-2-(phenylamino)acetamide With acetic acid In methanol; water at 0 - 20℃; for 24h;	81%

: 99-30-9
4-nitro-2,6-dichloroaniline

: 6375-46-8
m-acetylamino-N,N-diethylanilne

: 88458-16-6
N,N-diethyl-4-(2,6-dichloro-4-nitrophenylazo)-3-acetylaminoaniline

Conditions

Conditions	Yield
Stage #1: 4-nitro-2,6-dichloroaniline With tert.-butylnitrite; naphthalene-1,5-disulfonate In 1,2-dimethoxyethane at 25℃; for 0.5h; Stage #2: m-acetylamino-N,N-diethylanilne With sodium carbonate; naphthalene-1,5-disulfonate In water at 0℃; for 0.166667h; pH=4 - 6;	78.77%
Stage #1: 4-nitro-2,6-dichloroaniline With naphthalene-1,5-disulfonate In ethyl acetate at 50℃; for 0.166667h; Stage #2: With tert.-butylnitrite In ethyl acetate at 25℃; for 0.333333h; Stage #3: m-acetylamino-N,N-diethylanilne With hydrogenchloride In water at 0 - 5℃; for 0.316667h;

: 64-18-6
formic acid

: 99-30-9
4-nitro-2,6-dichloroaniline

: 70106-94-4
N-(2,6-dichloro-4-nitrophenyl)formamide

Conditions

Conditions	Yield
Stage #1: formic acid With acetic anhydride at 70 - 80℃; for 1h; Stage #2: 4-nitro-2,6-dichloroaniline for 3h; Heating;	78%
Stage #1: formic acid With acetic anhydride at 55 - 60℃; for 0.333333h; Stage #2: 4-nitro-2,6-dichloroaniline at 55℃; for 6.33333h;	65%

: 99-30-9
4-nitro-2,6-dichloroaniline

: 1395499-28-1
2-(2'-anthraquinonylamino-3'-hydroxy)-4-anilino-6-chloro-s-triazine

: 1395499-25-8
C29H17Cl2N7O5

Conditions

Conditions	Yield
In nitrobenzene at 60 - 65℃; for 5h;	76%

: 99-30-9
4-nitro-2,6-dichloroaniline

: 90-15-3
α-naphthol

: C16H9Cl2N3O3

Conditions

Conditions	Yield
Stage #1: 4-nitro-2,6-dichloroaniline With sulfuric acid; sodium nitrite In 1,2-dimethoxyethane; water at 0 - 5℃; for 1.25h; Stage #2: α-naphthol With sodium carbonate In water at 0 - 70℃; for 7h; pH=9 - 10;	75.61%

: 99-30-9
4-nitro-2,6-dichloroaniline

: 609-20-1
2,6-dichloro-p-phenylenediamine

Conditions

Conditions	Yield
With hydrogenchloride; tin(ll) chloride	75%
With ethanol; ammonium chloride; zinc
With ethanol; nickel Hydrogenation;

: 99-30-9
4-nitro-2,6-dichloroaniline

: 112-38-9
10-undecenoic acid

: 76691-53-7
Undec-10-enoic acid (2,6-dichloro-4-nitro-phenyl)-amide

Conditions

Conditions	Yield
With triethylamine; trichlorophosphate In dichloromethane	75%

: 99-30-9
4-nitro-2,6-dichloroaniline

: 135-19-3
β-naphthol

: 23648-85-3
1-(2,6-dichloro-4-nitro-phenylazo)-[2]naphthol

Conditions

Conditions	Yield
Stage #1: 4-nitro-2,6-dichloroaniline With sulfuric acid; sodium nitrite In 1,2-dimethoxyethane; water at 0 - 5℃; for 1.25h; Stage #2: β-naphthol With sodium carbonate In water at 0 - 70℃; for 7h; pH=9 - 10;	73.28%

: 99-30-9
4-nitro-2,6-dichloroaniline

: 320778-92-5
(1R,2R)-N,N-dimethylcyclohexane-1,2-diamine

: 530-62-1
1,1'-carbonyldiimidazole

: 1365611-35-3
C15H20Cl2N4O3

Conditions

Conditions	Yield
Stage #1: 4-nitro-2,6-dichloroaniline With potassium hydride In tetrahydrofuran at 0℃; for 0.25h; Inert atmosphere; Stage #2: 1,1'-carbonyldiimidazole In tetrahydrofuran; 1,4-dioxane at 0 - 20℃; Inert atmosphere; Stage #3: (1R,2R)-N,N-dimethylcyclohexane-1,2-diamine In tetrahydrofuran; 1,4-dioxane at 20℃; for 20h; Inert atmosphere;	73%

...Expand

: 99-30-9
4-nitro-2,6-dichloroaniline

: 22065-57-2
ethyl 2-phenyldiazoacetate

: ethyl 2-((2,6-dichloro-4-nitrophenyl)amino)-2-phenylacetate

Conditions

Conditions	Yield
With C43H37Br2CuN3P2(1+)*ClO4(1-) In dichloromethane at 0 - 20℃; for 5h; Schlenk technique; Inert atmosphere; chemoselective reaction;	71%

: 99-30-9
4-nitro-2,6-dichloroaniline

: 583-05-1
1-phenylpentane-1,4-dione

: 2,6-dichloro-4-(2-methyl-5-phenyl-1H-pyrrol-1-yl)aniline

Conditions

Conditions	Yield
With indium; acetic acid In toluene for 12h; Inert atmosphere; Reflux;	67%

2,6-Dichloro-4-nitroaniline Consensus Reports

EPA Genetic Toxicology Program. Reported in EPA TSCA Inventory.

2,6-Dichloro-4-nitroaniline Specification

The Benzenamine,2,6-dichloro-4-nitro-, with the CAS registry number 99-30-9, is also known as 2,6-Dichloro-4-nitrobenzenamine. It belongs to the product categories of Intermediates of Dyes and Pigments; Pharmaceutical intermediate. Its EINECS number is 202-746-4. This chemical's molecular formula is C₆H₄Cl₂N₂O₂ and molecular weight is 207.01. What's more, its systematic name is 2,6-dichloro-4-nitroaniline. Its classification codes are: (1)Agricultural Chemical; (2)Fungicide, bactericide, wood preservative; (3)Mutation data; (4)Tumor data. It should be sealed and stored in a cool, ventilated and dry place. Moreover, it should be protected from oxides, strong acids, heat and fire. It should also be prevented from direct sunlight. It is used as dye intermediates.

Physical properties of Benzenamine,2,6-dichloro-4-nitro- are: (1)ACD/LogP: 3.54; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 3.54; (4)ACD/LogD (pH 7.4): 3.54; (5)ACD/BCF (pH 5.5): 287.48; (6)ACD/BCF (pH 7.4): 287.48; (7)ACD/KOC (pH 5.5): 2002.05; (8)ACD/KOC (pH 7.4): 2002.05; (9)#H bond acceptors: 4; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 2; (12)Polar Surface Area: 49.06 Å²; (13)Index of Refraction: 1.655; (14)Molar Refractivity: 46.82 cm³; (15)Molar Volume: 127.4 cm³; (16)Polarizability: 18.56×10^-24cm³; (17)Surface Tension: 63.8 dyne/cm; (18)Density: 1.624 g/cm³; (19)Flash Point: 149.1 °C; (20)Enthalpy of Vaporization: 56.49 kJ/mol; (21)Boiling Point: 323 °C at 760 mmHg; (22)Vapour Pressure: 0.000269 mmHg at 25°C.

Preparation: this chemical can be prepared by paranitroaniline chloridizing in the mixture of hydrochloric acid and glacial acetic acid.

Uses of Benzenamine,2,6-dichloro-4-nitro-: it can be used to produce 1,2,3-trichloro-5-nitro-benzene. It will need reagents conc. aq. HCl, conc. aq. H₂SO₄, Cu₂Cl₂ and solvent acetic acid with the reaction time of 1 hour. The yield is about 47%.

Benzenamine,2,6-dichloro-4-nitro- can be used to produce 1,2,3-trichloro-5-nitro-benzene

When you are using this chemical, please be cautious about it as the following:
This chemical is harmful by inhalation, in contact with skin and if swallowed. It is irritating to eyes, respiratory system and skin. It has a danger of cumulative effects. You should not breathe dust. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. When using it, you need wear suitable protective clothing, gloves and eye/face protection.

You can still convert the following datas into molecular structure:
(1)SMILES: Clc1cc(cc(Cl)c1N)[N+]([O-])=O
(2)Std. InChI: InChI=1S/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2
(3)Std. InChIKey: BIXZHMJUSMUDOQ-UHFFFAOYSA-N

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
duck	LD50	oral	> 2gm/kg (2000mg/kg)		Pesticide Manual. Vol. 9, Pg. 265, 1991.
guinea pig	LD50	oral	1450mg/kg (1450mg/kg)		Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 343, 1966.
mammal (species unspecified)	LD50	unreported	1500mg/kg (1500mg/kg)		"Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 87, 1971.
mouse	LD50	intravenous	56mg/kg (56mg/kg)		U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#03022.
mouse	LD50	oral	1500mg/kg (1500mg/kg)		Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 343, 1966.
mouse	LD50	skin	> 5gm/kg (5000mg/kg)		Pesticide Manual. Vol. 9, Pg. 265, 1991.
mouse	LD50	unreported	4490mg/kg (4490mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT BEHAVIORAL: ATAXIA	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 54(11), Pg. 4, 1989.
rabbit	LD50	skin	> 2gm/kg (2000mg/kg)		Pesticide Manual. Vol. 9, Pg. 265, 1991.
rat	LC50	inhalation	> 21600mg/m³/1 (21600mg/m³)		Pesticide Manual. Vol. 9, Pg. 265, 1991.
rat	LD50	oral	2400mg/kg (2400mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA	Office of Toxic Substances Report. Vol. OTS.

Product Name

2,6-Dichloro-4-nitroaniline

Synthetic route

2,6-Dichloro-4-nitroaniline Consensus Reports

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