2-Chloroethyl ethyl sulfide supplier

Name
2-Chloroethyl ethyl sulfide
EINECS 211-742-1
CAS No. 693-07-2
Article Data16
CAS DataBase
Density 1.07
Solubility insoluble
Melting Point
Formula C₄H₉ClS
Boiling Point 156-157 ºC
Molecular Weight 124.634
Flash Point 52 ºC
Transport Information UN 1992
Appearance clear colourless to light yellow liquid
Safety Poison by ingestion and subcutaneous routes. Mutation data reported. A severe skin and eye irritant. See also ETHERS and SULFIDES. When heated to decomposition it emits very toxic fumes of Cl⁻ and SO_x.
Risk Codes R10;R22;R36/37/38;R40
Molecular Structure
Hazard Symbols
Synonyms Sulfide,2-chloroethyl ethyl (6CI,7CI,8CI);1-Chloro-2-(ethylsulfanyl)ethane;1-Chloro-2-(ethylthio)ethane;2-(Ethylthio)chloroethane;2-Chlorodiethylsulfide;2-Chloroethyl ethyl sulfide;2-Chloroethyl ethyl thioether;2-Ethylthioethyl chloride;Ethyl 2-chloroethyl sulfide;H-MG;Half-sulfurmustard;NSC 10977;
PSA 25.30000
LogP 1.97830

Synthetic route

: 107-06-2
1,2-dichloro-ethane

: 75-08-1
ethanethiol

A: 5395-75-5
1,2-bis(ethylthio)ethane

B: 693-07-2
2-Chloroethyl ethyl sulfide

Conditions

Conditions	Yield
Stage #1: ethanethiol With potassium hydroxide; hydrazine hydrate for 1h; Stage #2: 1,2-dichloro-ethane at 50℃; for 2h;	A 68% B 6%

...Expand

: 74-85-1
ethene

: 1496-75-9
Ethanesulfenyl chloride

: 693-07-2
2-Chloroethyl ethyl sulfide

Conditions

Conditions	Yield
at -10 - -5℃;

: 110-77-0
2-(ethylsulfanyl)ethanol

: 693-07-2
2-Chloroethyl ethyl sulfide

Conditions

Conditions	Yield
With hydrogenchloride
With thionyl chloride; chloroform
With phosphorus trichloride
With thionyl chloride In chloroform Heating;
With thionyl chloride

: 860213-87-2
1-ethylsulfanyl-2-butoxy-ethane

: 693-07-2
2-Chloroethyl ethyl sulfide

Conditions

Conditions	Yield
With 1,4-dioxane; hydrogenchloride

: 107-06-2
1,2-dichloro-ethane

: 811-51-8
sodium thioethylate

: 693-07-2
2-Chloroethyl ethyl sulfide

Conditions

Conditions	Yield
With methanol

: Ethyl-(2-ethylsulfanyl-ethyl)-(2-hydroxy-ethyl)-sulfonium

A: 5395-75-5
1,2-bis(ethylthio)ethane

B: 75-00-3
chloroethane

C: 110-77-0
2-(ethylsulfanyl)ethanol

D: 5648-30-6
6-oxa-3,9-dithiaundecane

E: 693-07-2
2-Chloroethyl ethyl sulfide

Conditions

Conditions	Yield
With hydrogenchloride In water at 90℃; for 1h; Product distribution; Mechanism;	A 2.4 % Chromat. B 2.3 % Chromat. C 44.9 % Chromat. D 2.9 % Chromat. E 44.9 % Chromat.

...Expand

: 7719-09-7
thionyl chloride

: 57830-41-8
3,6-dithiaoctan-1-ol

A: 505-29-3
1,4-Dithiane

B: 693-07-2
2-Chloroethyl ethyl sulfide

Conditions

Conditions	Yield
at 100℃;

...Expand

: 7719-09-7
thionyl chloride

: 57830-41-8
3,6-dithiaoctan-1-ol

A: 505-29-3
1,4-Dithiane

B: 92569-22-7
1-chloro-3,6-dithiaoctane

C: 693-07-2
2-Chloroethyl ethyl sulfide

Conditions

Conditions	Yield
at 35℃;

...Expand

: 693-07-2
2-Chloroethyl ethyl sulfide

: 627-50-9
vinyl ethylsulfide

Conditions

Conditions	Yield
With potassium hydroxide; triisopropylsilanol In N,N-dimethyl-formamide Ambient temperature;	100%
With potassium tert-butylate Kinetics;
With potassium hydroxide; triisopropylsilanol In N,N-dimethyl-formamide at 25℃;	100 % Chromat.

: 693-07-2
2-Chloroethyl ethyl sulfide

: 27998-62-5
2-chloroethyl ethyl sulfoxide

Conditions

Conditions	Yield
With methanesulfonic acid; urea hydrogen peroxide adduct In methanol Flow reactor;	98%
With N-(tert-butyl)-N-chloro-cyanamide In water; acetonitrile	97%
With 1,8-diazabicyclo[5.4.0]undec-7-ene hydrobromide-perbromide In water; acetonitrile at 20℃; for 0.0166667h;	94%

: 616-47-7
1-methyl-1H-imidazole

: 693-07-2
2-Chloroethyl ethyl sulfide

: [Me(C3H3N2)CH2CH2SEt]Cl

Conditions

Conditions	Yield
In diethyl ether at 0℃; for 24h; Inert atmosphere; Schlenk technique; Reflux;	97%
In toluene Heating;
at 120℃; for 2h; Neat (no solvent); Inert atmosphere;

: 1253202-16-2
C6H10N2S

: 693-07-2
2-Chloroethyl ethyl sulfide

: 1253202-03-7
N-ethyl-methyl-sulfide-N'-ethyl-ethyl-sulfide imidazoliumchloride

Conditions

Conditions	Yield
at 120℃; for 2h;	95%

: trans-dioxo(5,10,15,20-tetramesitylporphirinato)ruthenium(VI)

: 693-07-2
2-Chloroethyl ethyl sulfide

: C64H70Cl2N4O2RuS2

Conditions

Conditions	Yield
With oxygen In benzene-d6 at 20℃; under 760.051 Torr; for 504h;	95%

: 27423-88-7
1-(2’-thioethyl)ethylimidazole

: 693-07-2
2-Chloroethyl ethyl sulfide

: 1253202-02-6
N,N'-bis(ethyl-ethyl-sulfide)imidazolium chloride

Conditions

Conditions	Yield
at 120℃; for 2h;	93%

: 693-07-2
2-Chloroethyl ethyl sulfide

: 81526-29-6
N,N-bis(2-(ethylthio)ethyl)amine

Conditions

Conditions	Yield
With ammonia; sodium hydroxide In methanol; ethanol at -15 - 20℃; for 17h;	92%

: 693-07-2
2-Chloroethyl ethyl sulfide

: 352-93-2
diethyl sulphide

Conditions

Conditions	Yield
With cyclopentylmagnesium bromide In diethyl ether; toluene at 70℃;	91%

: 693-07-2
2-Chloroethyl ethyl sulfide

: 25027-40-1
2-chloroethyl ethyl sulfone

Conditions

Conditions	Yield
With m-chloroperoxybenzoic acid In dichloromethane	90%
With 2,6-di-tert-butyl-pyridine; tert-butylammonium hexafluorophosphate(V) In water; acetonitrile for 12h; electrolysis at controlled potential;	80%
With potassium permanganate; sulfuric acid In water; acetonitrile at 0℃; for 17h;	80%

: 110-77-0
2-(ethylsulfanyl)ethanol

: 693-07-2
2-Chloroethyl ethyl sulfide

: 107327-28-6
ethyl(2-(ethylthio)ethyl)(2-hydroxyethyl)sulfonium chloride

Conditions

Conditions	Yield
In water at 20℃;	85%

: 25364-44-7
N-(2,4,6-trimethylphenyl)imidazole

: 693-07-2
2-Chloroethyl ethyl sulfide

: 1242931-12-9
N-(2,4,6-trimethylphenyl)-N'-ethyl-ethyl-sulfide imidazolium iodide

Conditions

Conditions	Yield
With sodium iodide In toluene at 120℃; for 2h; Inert atmosphere;	84%

: (+/-)-3-(trans-3,4-dimethylpiperidinyl)phenol

: 693-07-2
2-Chloroethyl ethyl sulfide

: (+/-)-3-{1-[2-(ethylsulfanyl)ethyl]-trans-3,4-dimethylpiperidinyl}phenol

Conditions

Conditions	Yield
With sodium iodide; sodium hydrogencarbonate In N,N-dimethyl-formamide	83%

: 107-15-3
ethylenediamine

: 693-07-2
2-Chloroethyl ethyl sulfide

: 70063-00-2
S-2-(2-aminoethylamino)ethyl ethyl sulfide

Conditions

Conditions	Yield
Inert atmosphere;	83%

: 3570-55-6
3-thiapentan-1,5-dithiol

: 693-07-2
2-Chloroethyl ethyl sulfide

: 37460-05-2
3,6,9,12,15-Pentathiaheptadecane

Conditions

Conditions	Yield
With sodium ethanolate In ethanol for 1h; Heating;	82%

: 693-07-2
2-Chloroethyl ethyl sulfide

: sodium 3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-thiolate

: 184697-90-3
6-(2-Ethylsulfanyl-ethylsulfanyl)-2H-[1,2,4]triazine-3,5-dione

Conditions

Conditions	Yield
In ethanol; water for 1h; Heating;	82%

: phenylmagnesium bromide

: 693-07-2
2-Chloroethyl ethyl sulfide

: 22914-08-5
<2-(ethylthio)ethyl>benzene

Conditions

Conditions	Yield
In diethyl ether; toluene at 70℃;	82%

: 25364-47-0
1-(2,6-diisopropylphenyl)-1H-imidazole

: 693-07-2
2-Chloroethyl ethyl sulfide

: 1242931-14-1
C2H5SC2H4C3H2N2C6H3(CH(CH3)2)2H(1+)*I(1-)=C2H5SC2H4C3H2N2C6H3(C3H7)2HI

Conditions

Conditions	Yield
With sodium iodide In toluene at 120℃; for 2h; Inert atmosphere;	81%

: 693-07-2
2-Chloroethyl ethyl sulfide

: 105-53-3
diethyl malonate

: 100048-61-1
(2-ethylsulfanyl-ethyl)-malonic acid diethyl ester

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile Reflux;	81%

: 693-07-2
2-Chloroethyl ethyl sulfide

A: 27998-62-5
2-chloroethyl ethyl sulfoxide

B: (2-chloroethyl)(ethyl)(2-(ethylthio)ethyl)sulfonium chloride

Conditions

Conditions	Yield
With urea hydrogen peroxide adduct at 23℃;	A 80% B 20%

: 3,6-di(piperidin-1-yl)-9H-xanthene-9-thione

: 693-07-2
2-Chloroethyl ethyl sulfide

: thiopyronin

Conditions

Conditions	Yield
In dichloromethane	80%

: 23092-56-0
2-mercapto-5-(1-methyl-5-nitro-2-imidazolyl)-1,3,4-thiadiazole

: 693-07-2
2-Chloroethyl ethyl sulfide

: C11H14N4O2S3

Conditions

Conditions	Yield
With potassium hydroxide In ethanol; water at 20℃;	76%

: 693-07-2
2-Chloroethyl ethyl sulfide

: 60-24-2
2-hydroxyethanethiol

: 57830-41-8
3,6-dithiaoctan-1-ol

Conditions

Conditions	Yield
With sodium ethanolate In ethanol at 40℃; for 7h;	73%

: 84451-65-0
tetramethylammonium 2-oxo-2-thio-1,3,2-oxazaphosphorinan

: 693-07-2
2-Chloroethyl ethyl sulfide

: 2-(2-Ethylsulfanyl-ethylsulfanyl)-[1,3,2]oxazaphosphinane 2-oxide

Conditions

Conditions	Yield
In benzene for 30h; Heating;	71%

: 693-07-2
2-Chloroethyl ethyl sulfide

: 16865-27-3
2-mercapto-5-(5-nitro-2-furyl)-1,3,4-thiadiazole

: C10H11N3O3S3

Conditions

Conditions	Yield
With potassium hydroxide In ethanol; water at 20℃;	70%

: 693-07-2
2-Chloroethyl ethyl sulfide

: 26750-44-7
2-ethylsulfanyl-ethanethiol

Conditions

Conditions	Yield
With thiourea at 100℃;	68%
With ethanol; potassium hydrosulfide
Stage #1: 2-Chloroethyl ethyl sulfide With thiourea In ethanol for 24h; Heating; Stage #2: With potassium hydroxide for 5h; Heating;

: sodium cyclopentadienide

: 693-07-2
2-Chloroethyl ethyl sulfide

: 728880-40-8
1-(2-ethylsulfanyl-ethyl)-cyclopenta-1,3-diene

Conditions

Conditions	Yield
In tetrahydrofuran for 4h; Heating;	68%

: 85103-35-1
5-(2-nitrophenyl)-1,3,4-thiadiazole-2-thiol

: 693-07-2
2-Chloroethyl ethyl sulfide

: 1041361-26-5
C12H13N3O2S3

Conditions

Conditions	Yield
With potassium hydroxide In ethanol; water at 20℃;	65%

: 38339-95-6
4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-hydroxybenzamide

: 693-07-2
2-Chloroethyl ethyl sulfide

: 122452-34-0
4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-ethylsulfanyl-ethoxy)-benzamide

Conditions

Conditions	Yield
With potassium carbonate; sodium iodide In N,N-dimethyl-formamide 1.) Room temp., 16 h; 2.) 50 deg C, 2 h;	61%

: 81188-34-3
2-(4-nitrophenyl)-1,3,4-thiadiazole-5-thiol

: 693-07-2
2-Chloroethyl ethyl sulfide

: 1041361-32-3
C12H13N3O2S3

Conditions

Conditions	Yield
With potassium hydroxide In ethanol; water at 20℃;	61%

2-Chloroethyl ethyl sulfide Specification

The IUPAC name of 2-Chloroethyl ethyl sulfide is 1-Chloro-2-ethylsulfanylethane , with the CAS registry number 693-07-2, it is also named as 1-Chloro-2-(ethylthio)ethane ; 2-(Ethylthio)chloroethane ; 2-Chloroethyl ethyl sulfide ; 2-Chloroethyl ethyl thioether ; 2-Chloroethyl(ethyl)sulfide ; 2-Ethylthioethyl chloride ; Chlordiethylsulfid ; Ethane, 1-chloro-2-(ethylthio)- . It belongs to the following product categories, such as Organic Building Blocks. This product must store at 0-6 °C. 2-Chloroethyl ethyl sulfide is clear colourless to light yellow liquid and is insoluble in water.

2-Chloroethyl ethyl sulfide is harmful by inhalation, in contact with skin and if swallowed so we should rinse immediately with plenty of water and seek medical advice if contact with eyes. We must keep away from sources of ignition and no smoking because it is flammable. 2-Chloroethyl ethyl sulfide is also irritating to eyes, respiratory system and skin so we must wear suitable protective clothing, gloves and eye/face protection when contect with it .

Toxicity of 2-Chloroethyl ethyl sulfide is following:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LDLo	subcutaneous	25mg/kg (25mg/kg)		National Technical Information Service. Vol. PB158-507,
rat	LD50	oral	252mg/kg (252mg/kg)		"Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972Vol. -, Pg. 170, 1972.

Product Name

2-Chloroethyl ethyl sulfide

Synthetic route

2-Chloroethyl ethyl sulfide Specification

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