Product Name

  • Name

    3,4-Dimethylbenzaldehyde

  • EINECS 227-770-2
  • CAS No. 5973-71-7
  • Article Data63
  • CAS DataBase
  • Density 1.003 g/cm3
  • Solubility Soluble in ethanol, ether, toluene. Insoluble in water.
  • Melting Point 225-226 °C
  • Formula C9H10O
  • Boiling Point 225.3 °C at 760 mmHg
  • Molecular Weight 134.178
  • Flash Point 97.7 °C
  • Transport Information
  • Appearance clear colorless to yellowish liquid
  • Safety 24/25-36/37-26
  • Risk Codes 36/37/38
  • Molecular Structure Molecular Structure of 5973-71-7 (3,4-Dimethylbenzaldehyde)
  • Hazard Symbols IrritantXi
  • Synonyms Benzaldehyde, 3,4-dimethyl-;
  • PSA 17.07000
  • LogP 2.11590

Synthetic route

3,4‐dimethylbenzaldoxime

3,4‐dimethylbenzaldoxime

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

3,4-dimethylbenzyl alcohol
6966-10-5

3,4-dimethylbenzyl alcohol

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

Conditions
ConditionsYield
With ammonium hydroxide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; oxygen In ethanol at 50℃; for 18h;96%
With ammonium hydroxide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; copper(ll) bromide at 80℃; for 20h;96%
With Iron(III) nitrate nonahydrate; oxygen; 2,3-dicyano-5,6-dichloro-p-benzoquinone In 1,2-dichloro-ethane at 60℃; for 3h; Schlenk technique; Green chemistry;96%
4-(chloromethyl)-1,2-dimethylbenzene
102-46-5

4-(chloromethyl)-1,2-dimethylbenzene

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

Conditions
ConditionsYield
With sodium nitrate; acetic acid In water for 3h; Reflux;92%
With potassium hydroxide; cetyltrimethylammonim bromide; potassium nitrate In water for 6h; pH=10 - 11; Reflux;81%
(chloro)(3,4-dimethylphenyl)methyl p-tolyl sulfoxide

(chloro)(3,4-dimethylphenyl)methyl p-tolyl sulfoxide

A

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

B

di(p-tolyl) disulfide
103-19-5

di(p-tolyl) disulfide

C

3,5-di(3,4-dimethylphenyl)-1,2,4,6-thiatriazine 1-oxide
307929-13-1

3,5-di(3,4-dimethylphenyl)-1,2,4,6-thiatriazine 1-oxide

D

3,4-dimethylbenzonitrile
22884-95-3

3,4-dimethylbenzonitrile

Conditions
ConditionsYield
With tetrasulphure tetranitride In 1,4-dioxane for 7h; Heating;A n/a
B 86%
C 22%
D n/a
3,4-dimethylbenzyl bromide
94416-66-7

3,4-dimethylbenzyl bromide

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

Conditions
ConditionsYield
With potassium nitrite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; oxygen In water for 5h; Reflux;85%
o-xylene
95-47-6

o-xylene

N,N,N',N'-tetraformylhydrazine
52023-52-6

N,N,N',N'-tetraformylhydrazine

A

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

B

3,4-Dimethylbenzaldehyd-azin

3,4-Dimethylbenzaldehyd-azin

Conditions
ConditionsYield
Stage #1: o-xylene; N,N,N',N'-tetraformylhydrazine With aluminium trichloride In 1,2-dichloro-ethane at -15 - 1℃; for 19h;
Stage #2: With water
A 9%
B 77%
carbon monoxide
201230-82-2

carbon monoxide

3,4-dimethyliodobenzene
31599-61-8

3,4-dimethyliodobenzene

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; formic acid; tetrabutylammonium tetrafluoroborate In N,N-dimethyl-formamide at 60℃; under 760 Torr; Carbonylation; Electrochemical reaction;76%
o-xylene
95-47-6

o-xylene

tris(diformylamino)methane
332047-72-0

tris(diformylamino)methane

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

Conditions
ConditionsYield
Stage #1: o-xylene; tris(diformylamino)methane With aluminium trichloride In 1,2-dichloro-ethane at -19 - 0℃;
Stage #2: With water Heating;
65%
With aluminium trichloride In 1,2-dichloro-ethane at -19 - -1℃; for 15h;42%
o-xylene
95-47-6

o-xylene

tris(diformylamino)methane
332047-72-0

tris(diformylamino)methane

A

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

B

3,3',4,4'-tetramethyl-1,2-diphenylethane
34101-86-5

3,3',4,4'-tetramethyl-1,2-diphenylethane

Conditions
ConditionsYield
With aluminium trichloride In 1,2-dichloro-ethane Product distribution; Further Variations:; reagent amount;A 64%
B 3%
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

3,4-dimethylbenzyl alcohol
6966-10-5

3,4-dimethylbenzyl alcohol

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

A

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

B

Hexamethyldisiloxane
107-46-0

Hexamethyldisiloxane

C

triphenylphosphine
603-35-0

triphenylphosphine

Conditions
ConditionsYield
With 2,6-dimethylpyridine; tetrabutylammonium tetrafluoroborate In acetonitrile at 40℃; Electrochemical reaction;A 61%
B 10%
C 72 %Spectr.
3,4-dimethylstyrene
27831-13-6

3,4-dimethylstyrene

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

Conditions
ConditionsYield
With 1-hydroxy-pyrrolidine-2,5-dione; graphitic carbon nitride; oxygen In acetonitrile at 20℃; Inert atmosphere; Irradiation;60%
o-xylene
95-47-6

o-xylene

triformylamine
25891-31-0

triformylamine

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

Conditions
ConditionsYield
With aluminium trichloride In 1,2-dichloro-ethane at -30 - -4℃; for 12h; Formylation;43%
ethanol
64-17-5

ethanol

3,4-dimethylbenzyl alcohol
6966-10-5

3,4-dimethylbenzyl alcohol

A

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

B

3-(3,4-dimethylphenyl)-2-propylene aldehyde

3-(3,4-dimethylphenyl)-2-propylene aldehyde

C

5-(3,4-dimethyl-phenyl)-penta-2,4-dienal

5-(3,4-dimethyl-phenyl)-penta-2,4-dienal

Conditions
ConditionsYield
With oxygen; potassium carbonate In 1,4-dioxane at 60℃; for 48h;A 40%
B 20%
C 30%
o-xylene
95-47-6

o-xylene

bis(diformylamino)methane
877680-60-9

bis(diformylamino)methane

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

Conditions
ConditionsYield
With aluminum (III) chloride In chlorobenzene at -12 - 18℃; for 22h;37%
o-xylene
95-47-6

o-xylene

triformylamine
25891-31-0

triformylamine

A

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

B

N-[bis-(3,4-dimethyl-phenyl)-methyl]-formamide

N-[bis-(3,4-dimethyl-phenyl)-methyl]-formamide

Conditions
ConditionsYield
With aluminium trichloride In chlorobenzene at -15 - -6℃; for 16h; Product distribution; Further Variations:; Temperatures; Reagents; Solvents; ratio; addition sequence; Formylation; condensation;A 30%
B n/a
o-xylene
95-47-6

o-xylene

carbon monoxide
201230-82-2

carbon monoxide

A

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

B

5-formyl-2,3-dimethylbenzenesulfonyl fluoride
139689-26-2

5-formyl-2,3-dimethylbenzenesulfonyl fluoride

Conditions
ConditionsYield
With antimony pentafluoride; fluorosulphonic acid at 0℃; under 760 Torr; for 96h; Yield given;A 6%
B n/a
hydrogen cyanide
74-90-8

hydrogen cyanide

o-xylene
95-47-6

o-xylene

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

Conditions
ConditionsYield
With hydrogenchloride; aluminium trichloride Zersetzung des Reaktionsproduktes mit Eis und Salzsaeure;
o-xylene
95-47-6

o-xylene

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

Conditions
ConditionsYield
With aluminium trichloride; hydrogen cyanide at 100℃; Einleiten von HCl und anschliessend Behandeln mit Eis und wss. HCl;
Multi-step reaction with 2 steps
1: aluminium chloride
2: diluted alkali
View Scheme
Multi-step reaction with 3 steps
1: aluminium chloride
2: diluted alkali
View Scheme
1,2,4-Trimethylbenzene
95-63-6

1,2,4-Trimethylbenzene

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

Conditions
ConditionsYield
With manganese(IV) oxide; sulfuric acid
With sulfuric acid In acetonitrile at 50 - 80℃; for 24h; Reagent/catalyst;
3,4-dimethyl-mandelic acid
5766-03-0

3,4-dimethyl-mandelic acid

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

β-chloro-3,4-dimethyl-styrene

β-chloro-3,4-dimethyl-styrene

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

Conditions
ConditionsYield
With permanganate(VII) ion; acetone
2,2,2-trichloro-1-(3,4-dimethyl-phenyl)-ethanol

2,2,2-trichloro-1-(3,4-dimethyl-phenyl)-ethanol

A

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

B

3,4-dimethyl-mandelic acid
5766-03-0

3,4-dimethyl-mandelic acid

Conditions
ConditionsYield
With diluted alkali
3,4-dimethyl-benzoic acid-(N-methyl-anilide)
349109-03-1

3,4-dimethyl-benzoic acid-(N-methyl-anilide)

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

Conditions
ConditionsYield
With tetrahydrofuran; lithium aluminium tetrahydride
3,4-dimethylphenylmagnesium bromide
89980-68-7

3,4-dimethylphenylmagnesium bromide

ethyl N-phenylformimidate
6780-49-0

ethyl N-phenylformimidate

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

Conditions
ConditionsYield
With diethyl ether anschliessend mit wss.HCl;
3,4-dimethylbenzoyl chloride
21900-23-2

3,4-dimethylbenzoyl chloride

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

Conditions
ConditionsYield
With Pd-BaSO4; xylene at 140 - 150℃; Hydrogenation;
chloroform
67-66-3

chloroform

3,4-dimethylbenzonitrile
22884-95-3

3,4-dimethylbenzonitrile

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

Conditions
ConditionsYield
With hydrogenchloride; diethyl ether; tin(ll) chloride Erwaermen des Reaktionsprodukts mit H2O;
methanol
67-56-1

methanol

4,4-dimethylcyclohexa-2,5-dienone
1073-14-9

4,4-dimethylcyclohexa-2,5-dienone

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

Conditions
ConditionsYield
titanium tetrachloride Irradiation;
(3,4-Dimethyl-phenyl)-nitromethan
33241-78-0

(3,4-Dimethyl-phenyl)-nitromethan

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

Conditions
ConditionsYield
With potassium permanganate
o-xylene
95-47-6

o-xylene

carbon monoxide
201230-82-2

carbon monoxide

A

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

B

2,3-dimethylbenzaldehyde
5779-93-1

2,3-dimethylbenzaldehyde

Conditions
ConditionsYield
With antimony pentafluoride; fluorosulphonic acid at 0℃; under 760 Torr; for 1h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
(4R,5R)-1-C-(1,2-dimethyl-4-nitrocyclohex-1-en-5-yl)carbaldehyde
125488-63-3

(4R,5R)-1-C-(1,2-dimethyl-4-nitrocyclohex-1-en-5-yl)carbaldehyde

A

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

B

4,5-dimethylcyclohexa-1,4-diene-1-carbaldehyde
82372-64-3

4,5-dimethylcyclohexa-1,4-diene-1-carbaldehyde

Conditions
ConditionsYield
With potassium carbonate In methanol for 1h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

acetone
67-64-1

acetone

(E)-4-(3,4-dimethylphenyl)but-3-en-2-one
97241-86-6

(E)-4-(3,4-dimethylphenyl)but-3-en-2-one

Conditions
ConditionsYield
With sodium hydroxide In water at 0 - 25℃; for 6h;100%
With sodium hydroxide
With sodium hydroxide In water at 25℃; for 12h;
3-{[bis-(2-hydroxy-propyl)-amino]-methyl}-N-(3-hydrazinocarbonyl-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)-benzamide
773071-20-8

3-{[bis-(2-hydroxy-propyl)-amino]-methyl}-N-(3-hydrazinocarbonyl-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)-benzamide

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

3-{[bis-(2-hydroxy-propyl)-amino]-methyl}-N-[3-(3,4-dimethyl-benzylidene-hydrazinocarbonyl)-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl]-benzamide

3-{[bis-(2-hydroxy-propyl)-amino]-methyl}-N-[3-(3,4-dimethyl-benzylidene-hydrazinocarbonyl)-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl]-benzamide

Conditions
ConditionsYield
In toluene at 20℃; for 15h; Heating / reflux;100%
3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

cis, trans-1,3-dimethylaminocyclohexane
2579-20-6

cis, trans-1,3-dimethylaminocyclohexane

C26H34N2
1217526-73-2

C26H34N2

Conditions
ConditionsYield
In methanol at 20℃; Molecular sieve;100%
In methanol at 20℃; Molecular sieve;
3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

N-prenyl-N-propargyltosylamide
132330-44-0

N-prenyl-N-propargyltosylamide

C24H29NO3S
1363388-69-5

C24H29NO3S

Conditions
ConditionsYield
Stage #1: N-prenyl-N-propargyltosylamide With ethylmagnesium bromide In tetrahydrofuran at 50℃; for 1h;
Stage #2: 3,4-dimethylbenzaldehyde In tetrahydrofuran at 20℃; for 3h;
100%
Stage #1: N-prenyl-N-propargyltosylamide With ethylmagnesium bromide In tetrahydrofuran at 50℃; for 1h;
Stage #2: 3,4-dimethylbenzaldehyde In tetrahydrofuran at 20℃; for 3h;
diethoxyphosphoryl-acetic acid ethyl ester
867-13-0

diethoxyphosphoryl-acetic acid ethyl ester

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

(E)-ethyl 3-(3,4-dimethylphenyl)acrylate
81069-49-0, 83004-26-6

(E)-ethyl 3-(3,4-dimethylphenyl)acrylate

Conditions
ConditionsYield
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With lithium chloride In tetrahydrofuran at 20℃; for 0.25h; Horner-Wadsworth-Emmons Olefination; Inert atmosphere;
Stage #2: 3,4-dimethylbenzaldehyde With 1,8-diazabicyclo[5.4.0]undec-7-ene In tetrahydrofuran Horner-Wadsworth-Emmons Olefination; Inert atmosphere;
100%
With tetrabutyl ammonium fluoride In tetrahydrofuran at 30℃; for 4h; Glovebox;99%
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In tetrahydrofuran at 20℃; for 0.5h;
Stage #2: 3,4-dimethylbenzaldehyde In tetrahydrofuran
3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

D-sorbitol
50-70-4

D-sorbitol

1,3:2,4-di-O-(3,4-dimethylbenzylidene)-D-sorbitol
135861-56-2

1,3:2,4-di-O-(3,4-dimethylbenzylidene)-D-sorbitol

Conditions
ConditionsYield
toluene-4-sulfonic acid In acetonitrile at 20℃; for 12h; Product distribution / selectivity;99%
With trimethyl orthoformate; bismuth(lll) trifluoromethanesulfonate In methanol at 20℃; for 48h; Product distribution / selectivity;99%
With trimethyl orthoformate; bismuth(lll) trifluoromethanesulfonate In methanol at 20℃; for 49h; Product distribution / selectivity; Heating / reflux;99%
tetrahydrofuran-2,4-dione
4971-56-6

tetrahydrofuran-2,4-dione

1-Phenyl-3-methyl-5-aminopyrazole
1131-18-6

1-Phenyl-3-methyl-5-aminopyrazole

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

4-(3,4-dimethylphenyl)-3-methyl-1-phenyl-1H-furo[3,4-e]pyrazolo[3,4-b]pyridine-5(7H)-one
1173933-03-3

4-(3,4-dimethylphenyl)-3-methyl-1-phenyl-1H-furo[3,4-e]pyrazolo[3,4-b]pyridine-5(7H)-one

Conditions
ConditionsYield
With N-benzyl-N,N,N-triethylammonium chloride In water at 90℃; for 10h;97%
With 1-n-butyl-3-methylimidazolim bromide at 95℃; for 2h;91%
3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

phenylboronic acid
98-80-6

phenylboronic acid

phenyl 3,4-dimethylbenzoate

phenyl 3,4-dimethylbenzoate

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene; 1,3-bis(mesityl)imidazolium chloride In dimethyl sulfoxide at 80℃; for 0.5h;97%
3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

A

o-xylene
95-47-6

o-xylene

B

1,2,4-Trimethylbenzene
95-63-6

1,2,4-Trimethylbenzene

Conditions
ConditionsYield
With palladium/alumina; hydrogen In hexane at 325℃; Flow reactor; Green chemistry;A 96.2%
B 3.8%
With hydrogen In hexane at 325℃; Flow reactor; Green chemistry;A 15.9%
B 84.2%
3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

1,3-cylohexanedione
504-02-9

1,3-cylohexanedione

1-amino-5,5-dimethylcyclohexen-3-one
873-95-0

1-amino-5,5-dimethylcyclohexen-3-one

(+/-)-9-(3,4-dimethylphenyl)-3,3-dimethyl-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-dione

(+/-)-9-(3,4-dimethylphenyl)-3,3-dimethyl-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-dione

Conditions
ConditionsYield
With N-benzyl-N,N,N-triethylammonium chloride In water at 100℃; for 6h;96%
N-(2-hydrazinocarbonyl-4-piperidin-1-yl-phenyl)-3,4-dimethoxy-benzamide
773071-41-3

N-(2-hydrazinocarbonyl-4-piperidin-1-yl-phenyl)-3,4-dimethoxy-benzamide

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

N-[2-(3,4-dimethyl-benzylidene-hydrazinocarbonyl)-4-piperidin-1-yl-phenyl]-3,4-dimethoxy-benzamide

N-[2-(3,4-dimethyl-benzylidene-hydrazinocarbonyl)-4-piperidin-1-yl-phenyl]-3,4-dimethoxy-benzamide

Conditions
ConditionsYield
acetic acid In toluene at 20 - 90℃; for 16h;96%
3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

guanidine hydrogen carbonate
124-46-9, 20734-13-8, 100224-74-6, 593-85-1

guanidine hydrogen carbonate

cyclohexanone
108-94-1

cyclohexanone

(E)-8-(3,4-dimethylbenzylidene)-4-(3,4-dimethylphenyl)-5,6,7,8-tetrahydroquinazolin-2-amine
1173717-46-8

(E)-8-(3,4-dimethylbenzylidene)-4-(3,4-dimethylphenyl)-5,6,7,8-tetrahydroquinazolin-2-amine

Conditions
ConditionsYield
With sodium hydroxide at 70℃; for 0.25h;96%
cycl-isopropylidene malonate
2033-24-1

cycl-isopropylidene malonate

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

dimedone
126-81-8

dimedone

aniline
62-53-3

aniline

3-(2-hydroxy-4,4-dimethyl-6-oxocyclohex-1-enyl)-3-(3,4-dimethylphenyl)-N-phenylpropanamide
1355049-39-6

3-(2-hydroxy-4,4-dimethyl-6-oxocyclohex-1-enyl)-3-(3,4-dimethylphenyl)-N-phenylpropanamide

Conditions
ConditionsYield
With N-benzyl-N,N,N-triethylammonium chloride In water at 90℃; for 12h;96%
3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

ethyl (E)-2-cyano-3-(3,4-dimethylphenyl)-2-propenoate

ethyl (E)-2-cyano-3-(3,4-dimethylphenyl)-2-propenoate

Conditions
ConditionsYield
With polyacrylonitrile fiber modified with triethylenetetramine In water at 50℃; for 3h; Knoevenagel condensation;96%
3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

3,4-dimethylbenzyl alcohol
6966-10-5

3,4-dimethylbenzyl alcohol

Conditions
ConditionsYield
With Cp*Ir(6,6'-dionato-2,2'-bipyridine)(H2O); hydrogen In tert-Amyl alcohol at 30℃; under 760.051 Torr; for 12h; Green chemistry;96%
With CdS(x)Se(1-x) x:0-1;; cesium acetate; para-thiocresol In toluene Sealed tube; Inert atmosphere; Irradiation;96%
With Cp*Ir(6,6'-dionato-2,2'-bipyridine)(H2O); isopropyl alcohol at 82℃; for 6h; Inert atmosphere; Schlenk technique; chemoselective reaction;94%
2-acetylpyridine
1122-62-9

2-acetylpyridine

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

N-Cyanoguanidine
127099-85-8, 780722-26-1

N-Cyanoguanidine

N-(4-(3,4-dimethylphenyl)-6-(pyridin-2-yl)pyrimidin-2-yl)cyanamide
1391405-52-9

N-(4-(3,4-dimethylphenyl)-6-(pyridin-2-yl)pyrimidin-2-yl)cyanamide

Conditions
ConditionsYield
With sodium hydroxide In ethanol at 80℃; for 1h;96%
1.3-propanedithiol
109-80-8

1.3-propanedithiol

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

2-(3,4-dimethylphenyl)-m-dithiane

2-(3,4-dimethylphenyl)-m-dithiane

Conditions
ConditionsYield
With [silica-OSi(OMe)2C3H6(N2C3(CH3)H2)C4H8SO3H]HSO4 In water for 2h;96%
With boron trifluoride diethyl etherate In dichloromethane Inert atmosphere;
5-amino-1H-indole
5192-03-0

5-amino-1H-indole

3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

dimedone
126-81-8

dimedone

8,9-dihydro-8,8-dimethyl-11-(3,4-dimethylphenyl)-3H-pyrrolo[3,2-a]acridin-10(6H,7H,11H)-one
1449762-71-3

8,9-dihydro-8,8-dimethyl-11-(3,4-dimethylphenyl)-3H-pyrrolo[3,2-a]acridin-10(6H,7H,11H)-one

Conditions
ConditionsYield
In ethanol for 10h; Reflux;96%
3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

anthranilic acid nitrile
1885-29-6

anthranilic acid nitrile

2-(3,4-dimethylphenyl)quinazolin-4(3Η)-one
1313761-04-4

2-(3,4-dimethylphenyl)quinazolin-4(3Η)-one

Conditions
ConditionsYield
With 1,10-Phenanthroline; caesium carbonate; copper dichloride In water at 80℃; for 12h;96%
Stage #1: anthranilic acid nitrile With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; butyraldehyde oxime In para-xylene at 70℃; Schlenk technique; Inert atmosphere;
Stage #2: 3,4-dimethylbenzaldehyde In para-xylene at 110℃; for 4h; Inert atmosphere; Schlenk technique;
83%
Stage #1: anthranilic acid nitrile With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; butyraldehyde oxime In para-xylene at 70℃; for 12h; Schlenk technique;
Stage #2: 3,4-dimethylbenzaldehyde In para-xylene at 20 - 110℃; for 4h; Schlenk technique;
83%

3,4-Dimethylbenzaldehyde Chemical Properties

Molecule structure of 3,4-Dimethylbenzaldehyde (CAS NO.5973-71-7):

IUPAC Name: 3,4-Dimethylbenzaldehyde 
Molecular Weight: 134.1751 g/mol
Molecular Formula: C9H10
Melting Point: 225-226 °C
Index of Refraction: 1.551
Molar Refractivity: 42.65 cm3
Molar Volume: 133.6 cm3
Surface Tension: 36.1 dyne/cm
Density: 1.003 g/cm3
Flash Point: 97.7 °C
Enthalpy of Vaporization: 46.18 kJ/mol
Boiling Point: 225.3 °C at 760 mmHg
Vapour Pressure: 0.0871 mmHg at 25 °C 
Sensitive: air sensitive
XLogP3: 2.7
H-Bond Acceptor: 1
Rotatable Bond Count: 1
Tautomer Count: 5
Exact Mass: 134.073165
MonoIsotopic Mass: 134.073165
Topological Polar Surface Area: 17.1
Heavy Atom Count: 10
Canonical SMILES: CC1=C(C=C(C=C1)C=O)C
InChI: InChI=1S/C9H10O/c1-7-3-4-9(6-10)5-8(7)2/h3-6H,1-2H3
InChIKey: POQJHLBMLVTHAU-UHFFFAOYSA-N
EINECS: 227-770-2
Product Categories: Benzene derivatives;Aromatic Aldehydes & Derivatives (substituted);Benzaldehyde;API intermediates;Aldehydes;C9;Carbonyl Compounds

3,4-Dimethylbenzaldehyde Uses

 3,4-Dimethylbenzaldehyde (CAS NO.5973-71-7) is used for the preparation of pharmaceutical intermediates, nucleation transparent agent, spices, etc.

3,4-Dimethylbenzaldehyde Safety Profile

Hazard Codes: IrritantXi
Risk Statements: 36/37/38 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 24/25-36/37-26 
S24/25:Avoid contact with skin and eyes. 
S36/37:Wear suitable protective clothing and gloves. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 3
Hazard Note: Irritant

3,4-Dimethylbenzaldehyde Specification

 3,4-Dimethylbenzaldehyde (CAS NO.5973-71-7) is also named as Benzaldehyde, 3,4-dimethyl- . 3,4-Dimethylbenzaldehyde (CAS NO.5973-71-7) is clear colorless to yellowish liquid.

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