3-Acetyl-1-propanol supplier

Name
3-Acetyl-1-propanol
EINECS 213-994-8
CAS No. 1071-73-4
Article Data119
CAS DataBase
Density 1.007 g/mL at 25 °C(lit.)
Solubility
Melting Point 2.5°C (estimate)
Formula C₅H₁₀O₂
Boiling Point 204 °C at 760 mmHg
Molecular Weight 102.133
Flash Point 93 °C
Transport Information
Appearance clear colorless liquid
Safety 37/39-26
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms 3-Acetopropanol;3-Acetyl-1-propanol;3-Acetylpropanol;4-Oxo-1-pentanol;5-Hydroxy-2-pentanone;NSC 19158;NSC 33940;g-Acetopropanol;g-Acetopropyl alcohol;2-Pentanone, 5-hydroxy-;
PSA 37.30000
LogP 0.34790

Synthetic route

: 5390-04-5
pent-1-yn-5-ol

: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With C20H44Cl4N8O4P4Pd2S2; water at 30℃; for 9h; Reagent/catalyst;	100%
With cisplatin In water at 37℃; for 120h;	67%
With water; mercury(II) sulfate

: 5185-97-7
4-oxopentyl acetate

: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With sodium methylate In methanol for 4.5h; Ambient temperature;	96%

: 63305-45-3
4-oxopentyl formate

: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With sodium methylate In methanol for 1.5h;	95%

: 626-95-9
1,4-Pentanediol

A: 1071-73-4
5-Hydroxy-2-pentanone

B: 5185-97-7
4-oxopentyl acetate

Conditions

Conditions	Yield
With dihydrogen peroxide; methyltrioxorhenium(VII); sodium bromide In acetic acid for 10h; Ambient temperature;	A 94% B 6%

: 626-95-9
1,4-Pentanediol

: 64-19-7
acetic acid

A: 1071-73-4
5-Hydroxy-2-pentanone

B: 5185-97-7
4-oxopentyl acetate

Conditions

Conditions	Yield
With dihydrogen peroxide; methyltrioxorhenium(VII); sodium bromide for 10h; Ambient temperature;	A 94% B 6%

...Expand

: 3-(2-methyl-[1,3]oxathian-2-yl)-propan-1-ol

: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With bis-[(trifluoroacetoxy)iodo]benzene; sodium iodide In dichloromethane at 20℃; for 0.25h; Ring cleavage; De(monothio)acetalization;	90%

: 5-(3-benzyloxypropyl)-1,2,3-oxadiazole 3-oxide

: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With palladium 10% on activated carbon; hydrogen In methanol at 20℃; under 760.051 Torr; for 2h;	78%

: 517-23-7
3-acetyl-2-oxo-4,5-dihydrofuran

A: 96-48-0
4-butanolide

B: 1071-73-4
5-Hydroxy-2-pentanone

C: 999-10-0
ethyl 4-hydroxybutanoate

D: 25560-91-2
ethyl 4-(acetyloxy)butanoate

Conditions

Conditions	Yield
With sodium hydroxide In ethanol; water at 200℃; for 2h;	A 75% B 5% C 8% D 12%
With sodium hydroxide In ethanol; water at 200℃; for 2h;	A 75% B 3% C 8% D 12%
With sodium hydroxide In ethanol; water at 200℃; for 2h; Product distribution; other reagent/educt ratio,;	A 15% B 16% C 4% D 62%
With sodium hydroxide In ethanol; water at 200℃; for 2h;	A 15% B 16% C 4% D 62%

...Expand

: 98-01-1
furfural

: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With hydrogen In water at 80℃; under 1500.15 Torr; for 20.4167h; Pressure; Temperature; Reagent/catalyst; Autoclave;	72%
With carbon dioxide; water; hydrogen at 60℃; under 30003 Torr; for 36h; Temperature; Autoclave;
With hydrogen In water at 80℃; under 7500.75 Torr; for 10h; Temperature; Reagent/catalyst; Pressure; Autoclave; Molecular sieve;
With hydrogen In water at 80℃; under 1500.15 Torr; for 20h;

: 626-95-9
1,4-Pentanediol

A: 1071-73-4
5-Hydroxy-2-pentanone

B: 1679-47-6
3-methyltetrahydro-2-furanone

Conditions

Conditions	Yield
With aluminum oxide; potassium permanganate; copper(II) sulfate at 20℃; for 36h;	A 30% B 70%

: 89625-16-1
3-diphenylphosphinoyl-5-hydroxypentan-2-one

: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With potassium hydroxide In ethanol; water at 60℃; for 2h;	65%
With sodium hydroxide In ethanol at 60℃; for 3h;	53%

: 765-43-5
Cyclopropyl methyl ketone

A: 7326-46-7
2-Methyl-tetrahydro-furan-2-ol

B: 7326-47-8
5-(2-methyl-tetrahydrofuran-2-yloxy)pentan-2-one

C: 1071-73-4
5-Hydroxy-2-pentanone

D: 93677-66-8
6-oxaundeca-2,10-dione

Conditions

Conditions	Yield
With copper(ll) bromide In diethyl ether; water at 180℃; for 6h;	A n/a B n/a C n/a D 64%

...Expand

: 98-01-1
furfural

A: 97-99-4
Tetrahydrofurfuryl alcohol

B: 626-95-9
1,4-Pentanediol

C: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With hydrogen; toluene-4-sulfonic acid In water at 140℃; under 11251.1 Torr; for 4h; Autoclave;	A 19% B 63% C 8%
With carbon dioxide; hydrogen In water at 80℃; under 30003 Torr; for 20h; Catalytic behavior; Reagent/catalyst; Temperature; Autoclave;	A 8% B 57% C 15%

...Expand

: 98-00-0
(2-furyl)methyl alcohol

: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With carbon dioxide; hydrogen at 60℃; under 30003 Torr; for 0.25h; Autoclave;	62%

: 626-95-9
1,4-Pentanediol

A: 1071-73-4
5-Hydroxy-2-pentanone

B: 108-29-2
5-methyl-dihydro-furan-2-one

Conditions

Conditions	Yield
With tris(cetylpyridinium) 12-tungstophosphate; dihydrogen peroxide In tert-butyl alcohol for 24h; Heating;	A 60% B 30%
With copper chromite; silica gel; stearic acid
With sodium hydroxide; copper chromite; stearic acid

: 626-95-9
1,4-Pentanediol

: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With 3,3-dimethyldioxirane In acetone	60%
With Celite; silver carbonate In benzene for 1h; Heating;
With water; fluorine; acetonitrile In chloroform at -10 - 0℃;
With Rhodococcus ruber DSM 44541 In acetone at 30℃; for 48h; pH=7.5;
With palladium on activated charcoal at 120 - 300℃; Reagent/catalyst;

: 98-01-1
furfural

A: 626-95-9
1,4-Pentanediol

B: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With hydrogen In water at 80℃; under 1500.15 Torr; for 20.4167h; Pressure; Temperature; Reagent/catalyst; Autoclave;	A 17% B 56%
With hydrogen In water at 80℃; under 1500.15 Torr; for 20h;

: 517-23-7
3-acetyl-2-oxo-4,5-dihydrofuran

A: 1071-73-4
5-Hydroxy-2-pentanone

B: 92745-95-4
3-hydroxy-4-(2-hydroxyethyl)-5-methylisoxazole

Conditions

Conditions	Yield
With sodium hydroxide; hydroxylamine hydrochloride at 0 - 5℃; for 1h;	A 24 % Chromat. B 48%

: 626-95-9
1,4-Pentanediol

A: 1071-73-4
5-Hydroxy-2-pentanone

B: 626-96-0
4-oxopentanal

C: 108-29-2
5-methyl-dihydro-furan-2-one

Conditions

Conditions	Yield
With oxygen In 2,4-dichlorophenoxyacetic acid dimethylamine; toluene at 80℃; for 4h;	A n/a B n/a C 44%

...Expand

: 98-01-1
furfural

A: 97-99-4
Tetrahydrofurfuryl alcohol

B: 98-00-0
(2-furyl)methyl alcohol

C: 626-95-9
1,4-Pentanediol

D: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With hydrogen In water at 140℃; under 11251.1 Torr; for 4h; Autoclave;	A 26% B 8% C 36% D 18%

...Expand

: 98-01-1
furfural

A: 97-99-4
Tetrahydrofurfuryl alcohol

B: 98-00-0
(2-furyl)methyl alcohol

C: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With carbon dioxide; hydrogen In water at 80℃; under 30003 Torr; for 20h; Catalytic behavior; Reagent/catalyst; Temperature; Time; Autoclave;	A 11% B 26% C 10%

...Expand

: 5390-04-5
pent-1-yn-5-ol

A: 7326-47-8
5-(2-methyl-tetrahydrofuran-2-yloxy)pentan-2-one

B: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With cisplatin In water at 37℃; for 48h;	A 22% B n/a

: 821-09-0
n-Pent-4-enyl alcohol

: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With pyridine; oxygen; isopropyl alcohol; palladium diacetate In toluene at 60℃; for 6h; Oxidation;	21%
With Rh(III)(tetra(p-sulfonatophenyl)porphyrinato)(OD2)2(3-); water at 60℃; pH=9; borate buffer;

: 1577-22-6
5-hexenoic acid

: 627-11-2
2-Chloroethyl chloroformate

: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
Stage #1: 5-hexenoic acid; 2-Chloroethyl chloroformate With triethylamine In tetrahydrofuran at -20℃; for 0.75h; Stage #2: With sodium tetrahydroborate In tetrahydrofuran; water at 0℃; for 3h;	5%

: 75-21-8
oxirane

: 1007476-32-5
sodium ethyl acetylacetate enolate

: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
Erwaermen des entstandenen α-Acetyl-butyrolactons mit 5prozentiger HCl;

: 96-47-9
2-methyltetrahydrofuran

: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With hydrogenchloride; water; hydrogen; palladium dichloride at 55 - 60℃; under 1520 - 1900 Torr; Product distribution; effect of catalyst poisons;
With diethyl ether; oxygen; dinitrogen tetraoxide at 30 - 40℃;
With calcium hypochlorite; acetic acid at 20℃; for 1h; regioselective reaction;
With diethyl ether; oxygen; manganese(II) acetate at 70℃;

: 3003-84-7
Tetrahydrofurfuryl chloride

: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With potassium tert-butylate; tert-butyl alcohol anschliessendes Behandeln mit wss.Schwefelsaeure;

: 1192-30-9
tetrahydrofurfuryl bromide

: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With potassium hydroxide; triethanolamine anschliessendes Behandeln mit wss.Schwefelsaeure;

: 1487-15-6
2-Methyl-4,5-dihydrofuran

: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With water
With hydrogenchloride

: 534-22-5
2-methylfuran

: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With hydrogenchloride; palladium on activated charcoal; acetone Hydrogenation;
With formic acid; nickel kieselguhr; hydrogen at 150℃; under 77228.3 Torr; Hydrogenation.Reagens 4: Wasser; Reagens 5: Dioxan;
With hydrogen In acetone
With 5%-palladium/activated carbon; water; hydrogen at 28℃; for 3h; Reagent/catalyst; Temperature;	448 g

: 1071-73-4
5-Hydroxy-2-pentanone

: 626-95-9
1,4-Pentanediol

Conditions

Conditions	Yield
With zirconium dioxide hydrate; isopropyl alcohol at 130℃; for 0.666667h; Meerwein-Ponndorf-Verley Reduction;	100%
With K12(Ga4(1,5-bis(2,3-dihydroxybenzamido)naphthalene))6; potassium phosphate; borane pyridine In water-d2 at 20℃; Inert atmosphere;	68%
With sodium hydroxide; sodium tetrahydroborate In methanol

: 1071-73-4
5-Hydroxy-2-pentanone

: 18162-48-6
tert-butyldimethylsilyl chloride

: 86864-59-7
5-((tert-butyldimethylsilyl)oxy)pentan-2-one

Conditions

Conditions	Yield
With 1H-imidazole In N,N-dimethyl-formamide Inert atmosphere;	99%
With 1H-imidazole In N,N-dimethyl-formamide for 12h; Ambient temperature;	89%
With dmap; triethylamine In dichloromethane at 0 - 20℃; for 4.5h; Inert atmosphere;	88%

: 1071-73-4
5-Hydroxy-2-pentanone

: 927-55-9
(±)-4-amino-1-pentanol

Conditions

Conditions	Yield
With ammonium hydroxide; hydrogen In ethanol; water at 80℃; under 15001.5 Torr; for 2h; Autoclave;	99%
Multi-step reaction with 2 steps 1: hydroxylamine hydrochloride; sodium hydrogencarbonate 2: nickel; hydrogen View Scheme

: 13154-24-0
triisopropylsilyl chloride

: 1071-73-4
5-Hydroxy-2-pentanone

: C14H30O2Si

Conditions

Conditions	Yield
With 1H-imidazole In dichloromethane at 20℃;	97%
With 1H-imidazole In dichloromethane at 20℃;	77%

: 617-86-7
triethylsilane

: 1071-73-4
5-Hydroxy-2-pentanone

: 5-(triethylsiloxy)pentan-2-one

Conditions

Conditions	Yield
With 2,3-Dihydro-1,3-diisopropyl-4,5-dimethylimidazol-2-ylidene In neat (no solvent) at 50℃; for 5h; Glovebox; Inert atmosphere; Schlenk technique; chemoselective reaction;	96%
With copper (I) tert-butoxide; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene In toluene at 24℃; for 5h;	84%

: 109-80-8
1.3-propanedithiol

: 1071-73-4
5-Hydroxy-2-pentanone

: 211873-52-8
2-methyl 2-(3'-hydroxypropyl-1')-1,3-dithiane

Conditions

Conditions	Yield
With copper bis(dodecyl sulfate) In water at 20℃; for 6h; Inert atmosphere;	96%
With vanadyl trifluoromethanesulfonate In dichloromethane; acetonitrile at 20℃; for 17h; Inert atmosphere; chemoselective reaction;	87%

: 994-30-9
triethylsilyl chloride

: 1071-73-4
5-Hydroxy-2-pentanone

: 5-(triethylsiloxy)pentan-2-one

Conditions

Conditions	Yield
With pyridine at 20℃; for 12h;	96%

: 603-76-9
1-methylindole

: 1071-73-4
5-Hydroxy-2-pentanone

: 959977-38-9
3-(tetrahydro-2-methylfuran-2-yl)-1-methyl-1H-indole

Conditions

Conditions	Yield
With tris(pentafluorophenyl)borate In 1,2-dichloro-ethane at 40℃;	96%

: 5390-04-5
pent-1-yn-5-ol

: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With C20H44Cl4N8O4P4Pd2S2; water at 30℃; for 9h; Reagent/catalyst;	100%
With cisplatin In water at 37℃; for 120h;	67%
With water; mercury(II) sulfate

: 5185-97-7
4-oxopentyl acetate

: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With sodium methylate In methanol for 4.5h; Ambient temperature;	96%

: 63305-45-3
4-oxopentyl formate

: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With sodium methylate In methanol for 1.5h;	95%

: 626-95-9
1,4-Pentanediol

A: 1071-73-4
5-Hydroxy-2-pentanone

B: 5185-97-7
4-oxopentyl acetate

Conditions

Conditions	Yield
With dihydrogen peroxide; methyltrioxorhenium(VII); sodium bromide In acetic acid for 10h; Ambient temperature;	A 94% B 6%

: 626-95-9
1,4-Pentanediol

: 64-19-7
acetic acid

A: 1071-73-4
5-Hydroxy-2-pentanone

B: 5185-97-7
4-oxopentyl acetate

Conditions

Conditions	Yield
With dihydrogen peroxide; methyltrioxorhenium(VII); sodium bromide for 10h; Ambient temperature;	A 94% B 6%

...Expand

: 3-(2-methyl-[1,3]oxathian-2-yl)-propan-1-ol

: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With bis-[(trifluoroacetoxy)iodo]benzene; sodium iodide In dichloromethane at 20℃; for 0.25h; Ring cleavage; De(monothio)acetalization;	90%

: 5-(3-benzyloxypropyl)-1,2,3-oxadiazole 3-oxide

: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With palladium 10% on activated carbon; hydrogen In methanol at 20℃; under 760.051 Torr; for 2h;	78%

: 517-23-7
3-acetyl-2-oxo-4,5-dihydrofuran

A: 96-48-0
4-butanolide

B: 1071-73-4
5-Hydroxy-2-pentanone

C: 999-10-0
ethyl 4-hydroxybutanoate

D: 25560-91-2
ethyl 4-(acetyloxy)butanoate

Conditions

Conditions	Yield
With sodium hydroxide In ethanol; water at 200℃; for 2h;	A 75% B 5% C 8% D 12%
With sodium hydroxide In ethanol; water at 200℃; for 2h;	A 75% B 3% C 8% D 12%
With sodium hydroxide In ethanol; water at 200℃; for 2h; Product distribution; other reagent/educt ratio,;	A 15% B 16% C 4% D 62%
With sodium hydroxide In ethanol; water at 200℃; for 2h;	A 15% B 16% C 4% D 62%

...Expand

: 98-01-1
furfural

: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With hydrogen In water at 80℃; under 1500.15 Torr; for 20.4167h; Pressure; Temperature; Reagent/catalyst; Autoclave;	72%
With carbon dioxide; water; hydrogen at 60℃; under 30003 Torr; for 36h; Temperature; Autoclave;
With hydrogen In water at 80℃; under 7500.75 Torr; for 10h; Temperature; Reagent/catalyst; Pressure; Autoclave; Molecular sieve;
With hydrogen In water at 80℃; under 1500.15 Torr; for 20h;

: 626-95-9
1,4-Pentanediol

A: 1071-73-4
5-Hydroxy-2-pentanone

B: 1679-47-6
3-methyltetrahydro-2-furanone

Conditions

Conditions	Yield
With aluminum oxide; potassium permanganate; copper(II) sulfate at 20℃; for 36h;	A 30% B 70%

: 89625-16-1
3-diphenylphosphinoyl-5-hydroxypentan-2-one

: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With potassium hydroxide In ethanol; water at 60℃; for 2h;	65%
With sodium hydroxide In ethanol at 60℃; for 3h;	53%

: 765-43-5
Cyclopropyl methyl ketone

A: 7326-46-7
2-Methyl-tetrahydro-furan-2-ol

B: 7326-47-8
5-(2-methyl-tetrahydrofuran-2-yloxy)pentan-2-one

C: 1071-73-4
5-Hydroxy-2-pentanone

D: 93677-66-8
6-oxaundeca-2,10-dione

Conditions

Conditions	Yield
With copper(ll) bromide In diethyl ether; water at 180℃; for 6h;	A n/a B n/a C n/a D 64%

...Expand

: 98-01-1
furfural

A: 97-99-4
Tetrahydrofurfuryl alcohol

B: 626-95-9
1,4-Pentanediol

C: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With hydrogen; toluene-4-sulfonic acid In water at 140℃; under 11251.1 Torr; for 4h; Autoclave;	A 19% B 63% C 8%
With carbon dioxide; hydrogen In water at 80℃; under 30003 Torr; for 20h; Catalytic behavior; Reagent/catalyst; Temperature; Autoclave;	A 8% B 57% C 15%

...Expand

: 98-00-0
(2-furyl)methyl alcohol

: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With carbon dioxide; hydrogen at 60℃; under 30003 Torr; for 0.25h; Autoclave;	62%

: 626-95-9
1,4-Pentanediol

A: 1071-73-4
5-Hydroxy-2-pentanone

B: 108-29-2
5-methyl-dihydro-furan-2-one

Conditions

Conditions	Yield
With tris(cetylpyridinium) 12-tungstophosphate; dihydrogen peroxide In tert-butyl alcohol for 24h; Heating;	A 60% B 30%
With copper chromite; silica gel; stearic acid
With sodium hydroxide; copper chromite; stearic acid

: 626-95-9
1,4-Pentanediol

: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With 3,3-dimethyldioxirane In acetone	60%
With Celite; silver carbonate In benzene for 1h; Heating;
With water; fluorine; acetonitrile In chloroform at -10 - 0℃;
With Rhodococcus ruber DSM 44541 In acetone at 30℃; for 48h; pH=7.5;
With palladium on activated charcoal at 120 - 300℃; Reagent/catalyst;

: 98-01-1
furfural

A: 626-95-9
1,4-Pentanediol

B: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With hydrogen In water at 80℃; under 1500.15 Torr; for 20.4167h; Pressure; Temperature; Reagent/catalyst; Autoclave;	A 17% B 56%
With hydrogen In water at 80℃; under 1500.15 Torr; for 20h;

: 517-23-7
3-acetyl-2-oxo-4,5-dihydrofuran

A: 1071-73-4
5-Hydroxy-2-pentanone

B: 92745-95-4
3-hydroxy-4-(2-hydroxyethyl)-5-methylisoxazole

Conditions

Conditions	Yield
With sodium hydroxide; hydroxylamine hydrochloride at 0 - 5℃; for 1h;	A 24 % Chromat. B 48%

: 626-95-9
1,4-Pentanediol

A: 1071-73-4
5-Hydroxy-2-pentanone

B: 626-96-0
4-oxopentanal

C: 108-29-2
5-methyl-dihydro-furan-2-one

Conditions

Conditions	Yield
With oxygen In 2,4-dichlorophenoxyacetic acid dimethylamine; toluene at 80℃; for 4h;	A n/a B n/a C 44%

...Expand

: 98-01-1
furfural

A: 97-99-4
Tetrahydrofurfuryl alcohol

B: 98-00-0
(2-furyl)methyl alcohol

C: 626-95-9
1,4-Pentanediol

D: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With hydrogen In water at 140℃; under 11251.1 Torr; for 4h; Autoclave;	A 26% B 8% C 36% D 18%

...Expand

: 98-01-1
furfural

A: 97-99-4
Tetrahydrofurfuryl alcohol

B: 98-00-0
(2-furyl)methyl alcohol

C: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With carbon dioxide; hydrogen In water at 80℃; under 30003 Torr; for 20h; Catalytic behavior; Reagent/catalyst; Temperature; Time; Autoclave;	A 11% B 26% C 10%

...Expand

: 5390-04-5
pent-1-yn-5-ol

A: 7326-47-8
5-(2-methyl-tetrahydrofuran-2-yloxy)pentan-2-one

B: 1071-73-4
5-Hydroxy-2-pentanone

Conditions

Conditions	Yield
With cisplatin In water at 37℃; for 48h;	A 22% B n/a

3-Acetyl-1-propanol Chemical Properties

Molecule structure of 3-Acetyl-1-propanol (CAS NO.1071-73-4):

IUPAC: 5-Hydroxypentan-2-one
Molecular Formula: C₅H₁₀O₂
Molecular Weight: 102.13 g/mol
Density: 1.007 g/mL at 25 °C(lit.)
Boiling Point: 204 °C at 760 mmHg
Flash Point: 93.3 °C
Index of Refraction: 1.42
Molar Refractivity: 26.77 cm³
Molar Volume: 105.6 cm³
Surface Tension: 32.7 dyne/cm
XLogP3-AA: -0.4
H-Bond Donor: 1
H-Bond Acceptor: 2
Rotatable Bond Count: 3
Tautomer Count: 3
Exact Mass: 102.06808
MonoIsotopic Mass: 102.06808
Topological Polar Surface Area: 37.3
Heavy Atom Count: 7
Canonical SMILES: CC(=O)CCCO
InChI: InChI=1S/C5H10O2/c1-5(7)3-2-4-6/h6H,2-4H2,1H3
InChIKey: JSHPTIGHEWEXRW-UHFFFAOYSA-N
EINECS: 213-994-8
Product Categories: straight chain compounds

3-Acetyl-1-propanol Uses

3-Acetyl-1-propanol (CAS NO.1071-73-4) is used as an important pharmaceutical intermediate for the production of chloroquine phosphate, which is an antimalarial. It can also be used in the production of vitamin B1.

3-Acetyl-1-propanol Toxicity Data With Reference

1.	orl-rat LD50:6400 mg/k	TNICS* Toxicology of New Industrial Chemical Substances. 13 (1973),118.
2.	ihl-rat LC:>2 g/m³/4H	TNICS* Toxicology of New Industrial Chemical Substances. 13 (1973),118.
3.	orl-mus LD50:1960 mg/kg	GISAAA Gigiena i Sanitariya. 43 (8)(1978),103.
4.	ihl-mus LC:>2 g/m³/4H	TNICS* Toxicology of New Industrial Chemical Substances. 13 (1973),118.
5.	orl-rbt LDLo:3500 mg/kg	GISAAA Gigiena i Sanitariya. 43 (8)(1978),103.
6.	orl-gpg LD50:2260 mg/kg	GISAAA Gigiena i Sanitariya. 43 (8)(1978),103.

3-Acetyl-1-propanol Safety Profile

Hazard Codes: Irritant Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 37/39-26
S37/39:Wear suitable gloves and eye/face protection.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 2
RTECS: UA4600000
Moderately toxic by ingestion and inhalation. When heated to decomposition it emits acrid smoke.

3-Acetyl-1-propanol Specification

3-Acetyl-1-propanol (CAS NO.1071-73-4) is also named as 3-Acetopropanol ; 3-Acetyl-1-propanol ; 3-Acetylpropanol ; 4-01-00-04006 (Beilstein Handbook Reference) ; 5-Hydroxy-2-pentanone ; AI3-08030 ; BRN 1740387 ; NSC 19158 ; NSC 33940 ; Propanol, 3-acetyl- ; gamma-Acetopropanol ; gamma-Acetylpropyl alcohol . 3-Acetyl-1-propanol (CAS NO.1071-73-4) is clear colorless liquid. It is miscible with water, soluble in alcohol and ether. 3-Acetyl-1-propanol should be kept away from heat, sparks, and flame and sources of ignition. Then it should be stored in a tightly closed container and stored in a cool, dry, well-ventilated area away from incompatible substances.

Product Name

3-Acetyl-1-propanol

Synthetic route

3-Acetyl-1-propanol Chemical Properties

3-Acetyl-1-propanol Uses

3-Acetyl-1-propanol Toxicity Data With Reference

3-Acetyl-1-propanol Safety Profile

3-Acetyl-1-propanol Specification

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