4,4'-Oxybisbenzoic acid supplier

Name
4,4'-Oxybisbenzoic acid
EINECS 218-683-0
CAS No. 2215-89-6
Article Data42
CAS DataBase
Density 1.395 g/cm³
Solubility Insoluble in water
Melting Point 329 °C
Formula C₁₄H₁₀O₅
Boiling Point 473.7 °C at 760 mmHg
Molecular Weight 258.23
Flash Point 184.1 °C
Transport Information
Appearance white crystal powder
Safety 26-36
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms Benzoicacid, 4,4'-oxydi- (6CI,7CI,8CI);Benzoic acid, p,p'-oxybis- (3CI);Benzoicacid, p,p'-oxydi- (4CI);4,4'-Dicarboxydiphenyl ether;4,4'-Dicarboxydiphenyloxide;4,4'-Oxybis(benzoic acid);4,4'-Oxydiphenylenedicarboxylic acid;4-(4-Carboxyphenoxy)benzoic acid;Diphenyl ether-4,4'-dicarboxylic acid;NSC 39046;
PSA 83.83000
LogP 2.87530

Synthetic route

: 14387-30-5
dimethyl 4,4'-oxydibenzoate

: 2215-89-6
oxybis(benzoic acid)

Conditions

Conditions	Yield
With water; potassium hydroxide In ethanol Concentration; Solvent;	96%

: 74-11-3
para-chlorobenzoic acid

: 99-96-7
4-hydroxy-benzoic acid

: 2215-89-6
oxybis(benzoic acid)

Conditions

Conditions	Yield
With potassium carbonate In sulfolane at 143 - 145℃; for 16h; Reagent/catalyst; Solvent; Temperature;	95.9%
With potassium carbonate In dimethyl sulfoxide for 0.0833333h; microwave irradiation;

: 6508-04-9
4-(4'-cyanophenoxy)benzonitrile

: 2215-89-6
oxybis(benzoic acid)

Conditions

Conditions	Yield
With water; potassium hydroxide In ethanol at 110 - 120℃; for 6h; Autoclave;	95%
With sulfuric acid
With potassium hydroxide for 12h; Heating;

: 1579-40-4
1,1'-oxybis(4-methyl-benzene)

: 2215-89-6
oxybis(benzoic acid)

Conditions

Conditions	Yield
With dihydrogen peroxide; sodium carbonate at 100℃; under 7500.75 Torr; for 18h; Reagent/catalyst; Pressure;	93%
With pyridine; cobalt(III) acetylacetonate; dihydrogen peroxide; sodium carbonate In acetic acid at 100℃; under 15001.5 Torr; for 6h; Reagent/catalyst; Temperature; Solvent; Pressure;	92%
With 2-chloroanthracene-9,10-dione; water; oxygen; trifluoroacetic acid In ethyl acetate for 72h; Irradiation;	70%

: 201230-82-2
carbon monoxide

: 2050-47-7
4,4'-dibromodiphenyl ether

: 2215-89-6
oxybis(benzoic acid)

Conditions

Conditions	Yield
With water; triethylamine; 1,4-di(diphenylphosphino)-butane; palladium dichloride In acetonitrile at 120℃; under 7500.75 Torr; for 10h;	92.6%

: 2362-18-7
bis-(4-chloromethyl-phenyl)-ether

: 2215-89-6
oxybis(benzoic acid)

Conditions

Conditions	Yield
With potassium permanganate

: 3030-53-3
4,4'-bis(chloroacetyl)diphenyl ether

: 2215-89-6
oxybis(benzoic acid)

Conditions

Conditions	Yield
With potassium permanganate

: 6336-34-1
4-(4-carbamoylphenoxyl)benzamide

: 2215-89-6
oxybis(benzoic acid)

: 109-72-8, 29786-93-4
n-butyllithium

: 60-29-7
diethyl ether

: 2050-47-7
4,4'-dibromodiphenyl ether

: 71-43-2
benzene

A: 2215-89-6
oxybis(benzoic acid)

B: 21120-68-3
4-(4-bromophenoxy)benzoic acid

Conditions

Conditions	Yield
anschliessendes Behandeln mit festem CO2;

...Expand

: 2615-11-4
4,4'-oxydiacetophenone

: 2215-89-6
oxybis(benzoic acid)

Conditions

Conditions	Yield
With silver nitrate
Stage #1: 4,4'-oxydiacetophenone With sodium hydroxide; sodium hypochlorite In water at 55℃; Stage #2: With hydrogenchloride In water	3.7 - 4.3 g

: 2215-76-1
4-(4-formylphenoxy)benzaldehyde

: 2215-89-6
oxybis(benzoic acid)

Conditions

Conditions	Yield
With sodium hypobromide

: 64-19-7
acetic acid

: 1579-40-4
1,1'-oxybis(4-methyl-benzene)

chromium trioxide: chromium trioxide

: 2215-89-6
oxybis(benzoic acid)

Conditions

Conditions	Yield
at 40℃;

...Expand

: 456-22-4
4-Fluorobenzoic acid

: 99-96-7
4-hydroxy-benzoic acid

: 2215-89-6
oxybis(benzoic acid)

Conditions

Conditions	Yield
With potassium carbonate In dimethyl sulfoxide for 0.0833333h; microwave irradiation;

: 586-76-5
4-Bromobenzoic acid

: 99-96-7
4-hydroxy-benzoic acid

: 2215-89-6
oxybis(benzoic acid)

Conditions

Conditions	Yield
With potassium carbonate In dimethyl sulfoxide for 0.0833333h; microwave irradiation;

: 201230-82-2
carbon monoxide

: 2050-47-7
4,4'-dibromodiphenyl ether

A: 2215-89-6
oxybis(benzoic acid)

B: 21120-68-3
4-(4-bromophenoxy)benzoic acid

Conditions

Conditions	Yield
With dicobalt octacarbonyl; potassium carbonate; methyloxirane In methanol at 60℃; under 760 Torr; for 4h; Title compound not separated from byproducts;

...Expand

: 623-03-0
4-Cyanochlorobenzene

/PBGLH020--460/: /PBGLH020--460/

: 2215-89-6
oxybis(benzoic acid)

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: K2CO3 / dimethylsulfoxide / 0.08 h / microwave irradiation 2: aq. KOH / 12 h / Heating View Scheme

: 1194-02-1
4-fluorobenzonitrile

: 2215-89-6
oxybis(benzoic acid)

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: K2CO3 / dimethylsulfoxide / 0.08 h / microwave irradiation 2: aq. KOH / 12 h / Heating View Scheme

: 623-00-7
4-bromobenzenecarbonitrile

: 2215-89-6
oxybis(benzoic acid)

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: K2CO3 / dimethylsulfoxide / 0.08 h / microwave irradiation 2: aq. KOH / 12 h / Heating View Scheme

: 767-00-0
4-cyanophenol

: 2215-89-6
oxybis(benzoic acid)

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: K2CO3 / dimethylsulfoxide / 0.08 h / microwave irradiation 2: aq. KOH / 12 h / Heating View Scheme
Multi-step reaction with 2 steps 1: K2CO3 / dimethylsulfoxide / 0.08 h / microwave irradiation 2: aq. KOH / 12 h / Heating View Scheme
Multi-step reaction with 2 steps 1: K2CO3 / dimethylsulfoxide / 0.08 h / microwave irradiation 2: aq. KOH / 12 h / Heating View Scheme

: 101-84-8
diphenylether

: 2215-89-6
oxybis(benzoic acid)

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: HCl; aqueous formaldehyde; acetic acid / Reagens 4: ZnCl2 2: KMnO4 View Scheme

: 106-38-7
para-bromotoluene

: 2215-89-6
oxybis(benzoic acid)

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: copper powder; p-cresol / 200 - 240 °C 2: chromium trioxide; glacial acetic acid / 40 °C View Scheme

: 1192-96-7
potassium p-cresolate

: 2215-89-6
oxybis(benzoic acid)

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: copper powder; p-cresol / 200 - 240 °C 2: chromium trioxide; glacial acetic acid / 40 °C View Scheme

: 4542-75-0
4,4'-oxybis-((bromomethyl)benzene)

: 2215-89-6
oxybis(benzoic acid)

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: Zn, AcOH, aq. CuSO4 2: aq. KMnO4 View Scheme

: 2215-77-2
4-Phenoxybenzoic acid

: 2215-89-6
oxybis(benzoic acid)

Conditions

Conditions	Yield
	2.0 mol %

: 619-42-1
4-methoxycarbonylphenyl bromide

: 99-76-3
methyl 4-hydroxylbenzoate

: 2215-89-6
oxybis(benzoic acid)

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: potassium hydroxide / toluene / 115 - 120 °C / Inert atmosphere 1.2: 170 - 180 °C 2.1: water; potassium hydroxide / ethanol View Scheme

: 1126-46-1
Methyl 4-chlorobenzoate

: 99-76-3
methyl 4-hydroxylbenzoate

: 2215-89-6
oxybis(benzoic acid)

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: potassium hydroxide / toluene / 115 - 120 °C / Inert atmosphere 1.2: 175 - 185 °C 2.1: water; potassium hydroxide / ethanol View Scheme

: 2215-89-6
oxybis(benzoic acid)

: 117011-70-8
2-(4-aminophenoxy)-2-methyl propionic acid

: 1365890-39-6
C34H32N2O9

Conditions

Conditions	Yield
Stage #1: oxybis(benzoic acid) With tert-butyl chloroformate; triethylamine In tetrahydrofuran Stage #2: 2-(4-aminophenoxy)-2-methyl propionic acid With sodium hydroxide In tetrahydrofuran; water for 2h; Stage #3: With acetic acid In water	100%

: 2215-89-6
oxybis(benzoic acid)

: N-[1-(4-Amino-phenyl)-1-phenyl-meth-(E)-ylidene]-benzene-1,4-diamine

Polymer; Monomer(s): OPA, oxybis(benzoic acid);: Polymer; Monomer(s): OPA, oxybis(benzoic acid);

Conditions

Conditions	Yield
With pyridine; 1-methyl-pyrrolidin-2-one; lithium chloride; triphenyl phosphite at 80℃;	99%

: 2215-89-6
oxybis(benzoic acid)

: 530-62-1
1,1'-carbonyldiimidazole

: 4,4'-biphenyletherdicarbonyl diimidazole

Conditions

Conditions	Yield
In 1-methyl-pyrrolidin-2-one at 36 - 62℃; Solvent; Temperature; Inert atmosphere;	99%

: 2215-89-6
oxybis(benzoic acid)

: 2-(2-{4'-[2-(2-{4-[bis-(4-tert-butyl-phenyl)-(4-ethyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethoxymethyl]-[2,2']bi[[1,3]dithiolylidene]-4-ylmethoxy}-ethoxy)-ethanol

: C116H130O15S8

Conditions

Conditions	Yield
With dmap; dicyclohexyl-carbodiimide In tetrahydrofuran; dichloromethane at 20℃; for 24h;	97%

: terbium(III) nitrate hexahydrate

: 2215-89-6
oxybis(benzoic acid)

: 68-12-2, 33513-42-7
N,N-dimethyl-formamide

: 7647-14-5
sodium chloride

: Na[Tb(4,4'-oxybis(benzoato))]*0.4DMF*1.5H2O

Conditions

Conditions	Yield
In ethanol; N,N-dimethyl-formamide High Pressure; Tb salt, ligand and NaCl added to DMF-EtOH; heated in autoclave at 150°C for 3 d; cooled slowly to 50°C; crystals obtained; elem. anal.;	96%

...Expand

: lead(II) nitrate

: 2215-89-6
oxybis(benzoic acid)

: 7732-18-5
water

: [Pb(4,4’-oxybis(benzoate))(μ-H2O)]n

Conditions

Conditions	Yield
With dapsone In N,N-dimethyl-formamide at 65℃; for 96h; Autoclave;	96%

...Expand

: zinc(II) sulfate heptahydrate

: 2215-89-6
oxybis(benzoic acid)

: 1465883-84-4
trans-2'-fluoro-4-styrylpyridine

: 2C14H8O5(2-)*2Zn(2+)*2C13H10FN

Conditions

Conditions	Yield
In water; N,N-dimethyl-formamide at 120℃; for 2h; Sealed tube;	96%

...Expand

: 2215-89-6
oxybis(benzoic acid)

: 7158-32-9
4,4'-bis(chlorocarbonyl)diphenyl oxide

Conditions

Conditions	Yield
With thionyl chloride In N,N-dimethyl-formamide; toluene at 95℃; for 3h;	95%
With thionyl chloride In N,N-dimethyl-formamide; toluene at 95℃; for 3h;	95%
With thionyl chloride; N,N-dimethyl-formamide In toluene at 95℃; for 3h;	95%

: 2215-89-6
oxybis(benzoic acid)

: 346701-88-0
2-(2-{5-[2-(2-{4-[bis-(4-tert-butyl-phenyl)-(4-ethyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethoxy]-naphthalen-1-yloxy}-ethoxy)-ethanol

: C120H130O15

Conditions

Conditions	Yield
With dmap; dicyclohexyl-carbodiimide In tetrahydrofuran; dichloromethane at 20℃; for 24h;	95%

: zinc(II) sulfate heptahydrate

: 31338-30-4, 147808-68-2
1-(4-pyridyl)-2-(3-methoxyphenyl)ethene

: 2215-89-6
oxybis(benzoic acid)

: 2C14H8O5(2-)*2Zn(2+)*2C14H13NO

Conditions

Conditions	Yield
In water; N,N-dimethyl-formamide at 120℃; for 2h; Sealed tube;	95%

...Expand

: ytterbium(III) nitrate pentahydrate

: 2215-89-6
oxybis(benzoic acid)

: 68-12-2, 33513-42-7
N,N-dimethyl-formamide

: 7647-14-5
sodium chloride

: Na[Yb(4,4'-oxybis(benzoato))]*0.4DMF*1.5H2O

Conditions

Conditions	Yield
With NaOH In ethanol; N,N-dimethyl-formamide High Pressure; Yb salt, ligand and NaCl added to DMF-EtOH; pH adjusted to ca. 6.0 (aq. NaOH); heated in autoclave at 150°C for 3 d; cooled slowly to 50°C; crystals obtained; elem. anal.;	93%

...Expand

: 2215-89-6
oxybis(benzoic acid)

: 4-(chlorosulfonyl)-10,10-dioxo-10λ6-phenoxathiin-2,8-dicarboxylic acid

Conditions

Conditions	Yield
With chlorosulfonic acid at 150℃; for 4h; regioselective reaction;	93%
With chlorosulfonic acid Heating;

: 2215-89-6
oxybis(benzoic acid)

: 4381-25-3
S-methyl-S-phenylsulfoximine

: N-4-(4,4'-oxydibenzoyl)-S-methyl-S-phenylsulfoximine

Conditions

Conditions	Yield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 20℃; for 13h; Schlenk technique; Inert atmosphere;	93%

: scandium(III) nitrate pentahydrate

: 2215-89-6
oxybis(benzoic acid)

: Sc(3+)*HO(1-)*C14H8O5(2-)

Conditions

Conditions	Yield
In water; N,N-dimethyl-formamide at 160℃; for 2h; Microwave irradiation;	93%

: 2215-89-6
oxybis(benzoic acid)

: 4-(4-carboxyphenoxy)-3-(chlorosulfonyl)benzoic acid

Conditions

Conditions	Yield
With chlorosulfonic acid at 60 - 70℃; regioselective reaction;	92%
With chlorosulfonic acid
With chlorosulfonic acid at 70℃; for 4h;

: 67-56-1
methanol

: 2215-89-6
oxybis(benzoic acid)

: 14387-30-5
dimethyl 4,4'-oxydibenzoate

Conditions

Conditions	Yield
With trichlorophosphate Reflux;	92%

: 2215-89-6
oxybis(benzoic acid)

: 7732-18-5
water

: samarium(III) nitrate

: 3C14H8O5(2-)*6H2O*2Sm(3+)

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 100 - 120℃; for 83h; Autoclave;	92%

...Expand

: zinc(II) sulfate heptahydrate

: 2215-89-6
oxybis(benzoic acid)

: (E)-4-(2-(pyridin-4-yl)vinyl)-2,3-dihydro-1H-inden-1-one

: 2C14H8O5(2-)*2Zn(2+)*2.2C16H13NO

Conditions

Conditions	Yield
In water; N,N-dimethyl-formamide at 120℃; for 2h; Sealed tube;	92%

...Expand

: zinc(II) sulfate heptahydrate

: 2215-89-6
oxybis(benzoic acid)

: C13H9F2N

: 2C14H8O5(2-)*2Zn(2+)*2C13H9F2N

Conditions

Conditions	Yield
In water; N,N-dimethyl-formamide at 120℃; for 2h; Sealed tube;	91%

...Expand

: zinc(II) sulfate heptahydrate

: 2215-89-6
oxybis(benzoic acid)

: C15H15N

: 2C14H8O5(2-)*2Zn(2+)*2C15H15N

Conditions

Conditions	Yield
In water; N,N-dimethyl-formamide at 120℃; for 2h; Sealed tube;	91%

...Expand

: 2215-89-6
oxybis(benzoic acid)

: 95-55-6
2-amino-phenol

: 305360-30-9
N-(2-hydroxyphenyl)-4-{3-[(2-hydroxyphenyl)carbamoyl]phenoxy}benzamide

Conditions

Conditions	Yield
Stage #1: oxybis(benzoic acid) With tert-butyl chloroformate; triethylamine In tetrahydrofuran at -78℃; Stage #2: 2-amino-phenol With sodium hydroxide In tetrahydrofuran; water for 2h;	91%

: 2215-89-6
oxybis(benzoic acid)

: 95-54-5
1,2-diamino-benzene

: 18509-48-3
4,4'-bis(2-benzimidazole)-diphenylether

Conditions

Conditions	Yield
With Eaton′s Reagent at 130℃; for 1h; Inert atmosphere;	90%

: zinc(II) nitrate hexahydrate

: 2215-89-6
oxybis(benzoic acid)

: 3,5-diethyl-4-(4'-pyridyl)pyrazole

: 68-12-2, 33513-42-7
N,N-dimethyl-formamide

: [Zn7O2(3,5-diethyl-4-(4'-pyridyl)pyrazole-(1H))2(4,4'-oxybisbenzoic acid-(2H))4]2 N,N-dimethylformamide dihydrate

Conditions

Conditions	Yield
In methanol at 150℃; for 72h; Sealed tube; Autoclave;	90%

...Expand

: 2215-89-6
oxybis(benzoic acid)

: 5970-45-6
zinc(II) acetate dihydrate

: N1,N4-bis((pyridin-4-yl)-methylene)benzene-1,4-diamine

: [Zn(oba)(4-bpmb)0.5]n

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 100℃; for 8.25h;	90%

...Expand

: cobalt(II) nitrate hexahydrate

: 2215-89-6
oxybis(benzoic acid)

: 2,8-di(1H-imidazol-1-yl)dibenzofuran

: 7732-18-5
water

: 3H2O*2Co(2+)*2C18H12N4O*2C14H8O5(2-)

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 95℃; for 72h; Autoclave;	90%

...Expand

4,4'-Oxybisbenzoic acid Chemical Properties

Molecular structure of 4,4'-Oxybisbenzoic acid (CAS NO.2215-89-6) is:

Product Name: 4,4'-Oxybisbenzoic acid
CAS Registry Number: 2215-89-6
IUPAC Name: 4-(4-carboxyphenoxy)benzoic acid
Molecular Weight: 258.2262 [g/mol]
Molecular Formula: C₁₄H₁₀O₅
XLogP3: 3.4
H-Bond Donor: 2
H-Bond Acceptor: 5
EINECS: 218-683-0
Melting Point: 329 °C
Surface Tension: 63.5 dyne/cm
Density: 1.395 g/cm³
Flash Point: 184.1 °C
Enthalpy of Vaporization: 77.63 kJ/mol
Boiling Point: 473.7 °C at 760 mmHg
Vapour Pressure: 8.85E-10 mmHg at 25°C
Product Categories: Industrial/Fine Chemicals;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Aromatic Ethers;Diphenyl Ethers (for High-Performance Polymer Research);Functional Materials;Reagent for High-Performance Polymer Research;Carboxylic Acid Monomers;Monomers;Polymer Science

4,4'-Oxybisbenzoic acid Safety Profile

Safty information about 4,4'-Oxybisbenzoic acid (CAS NO.2215-89-6) is:
Hazard Codes: Irritant Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
WGK Germany: 3

4,4'-Oxybisbenzoic acid Specification

4,4'-Oxybisbenzoic acid , its cas register number is 2215-89-6. It also can be called Benzoic acid, 4,4'-oxybis- ; 4-(4-Carboxyphenoxy)benzoic acid .It is a white to pale brown solid.

Product Name

4,4'-Oxybisbenzoic acid

Synthetic route

4,4'-Oxybisbenzoic acid Chemical Properties

4,4'-Oxybisbenzoic acid Safety Profile

4,4'-Oxybisbenzoic acid Specification

Related Products

Hot Products