7-Benzyloxy-4-chloro-6-methoxy-quinoline supplier

: 205448-29-9, 849217-23-8
4-hydroxy-6-methoxy-7-benzyloxyquinoline

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

Conditions

Conditions	Yield
Stage #1: 7-benzyloxy-4-hydroxy-6-methoxyquinoline With trichlorophosphate for 2h; Heating / reflux; Stage #2: With sodium hydrogencarbonate; sodium carbonate In water at 20℃; pH=8;	95%
With trichlorophosphate for 2h; Heating / reflux;	95%
With trichlorophosphate In toluene at 120℃; for 1.5h;	90%

: 205448-31-3
4-chloro-6-methoxy-7-hydroxyquinoline

: 100-39-0
benzyl bromide

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 45℃; for 2h;	95%

: 205448-29-9, 849217-23-8
6-methoxy-7-benzyloxy-4(1H)-quinolinone

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

Conditions

Conditions	Yield
Stage #1: 6-methoxy-7-benzyloxy-4(1H)-quinolinone With trichlorophosphate at 110℃; for 3h; Stage #2: With sodium carbonate In chloroform; water Cooling with ice;	94%
With sodium hydroxide; trichlorophosphate In chloroform	21%
With trichlorophosphate In acetonitrile for 6h; Reflux;	174.8 g

: 75665-73-5
1-(2-amino-4-(benzyloxy)-5-methoxyphenyl)ethanone

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: sodium methylate / Dimethyl ether / 0.5 h / 20 °C 1.2: 8 h 2.1: trichlorophosphate / toluene / 2 h / Reflux View Scheme
Multi-step reaction with 2 steps 1.1: sodium methylate / 1,2-dimethoxyethane / 0.5 h / Inert atmosphere 1.2: Inert atmosphere 2.1: trichlorophosphate / 10 h / Reflux View Scheme
Multi-step reaction with 2 steps 1.1: sodium methylate / 1,2-dimethoxyethane / 0.5 h 1.2: 15 h / 20 °C 2.1: trichlorophosphate / 4.33 h / Cooling with ice; Reflux View Scheme

: 100-39-0
benzyl bromide

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1.1: potassium carbonate / N,N-dimethyl-formamide / 5 h / 40 °C 2.1: nitric acid; sulfuric acid / dichloromethane / 1 h / 0 °C / pH 7 - 8 3.1: ammonium formate; iron / toluene; water / 103 °C 4.1: sodium methylate / Dimethyl ether / 0.5 h / 20 °C 4.2: 8 h 5.1: trichlorophosphate / toluene / 2 h / Reflux View Scheme
Multi-step reaction with 5 steps 1.1: potassium carbonate / N,N-dimethyl-formamide / 40 °C 2.1: nitric acid; sulfuric acid / dichloromethane / 2.25 h / 0 °C 3.1: iron; ammonium acetate / toluene; water / 105 °C 4.1: sodium methylate / 1,2-dimethoxyethane / 0.5 h / Inert atmosphere 4.2: Inert atmosphere 5.1: trichlorophosphate / 10 h / Reflux View Scheme
Multi-step reaction with 5 steps 1.1: potassium carbonate / N,N-dimethyl-formamide / 0.25 h / 20 °C 1.2: 4 h / 20 °C 2.1: nitric acid / dichloromethane / 2 h / -20 - -10 °C 3.1: 5,5-dimethyl-1,3-cyclohexadiene / 15 h / Reflux 4.1: iron; acetic acid / 2 h / 60 - 90 °C 5.1: trichlorophosphate / acetonitrile / 6 h / Reflux View Scheme

: 1835-11-6
4-benzyloxy-3-methoxyacetophenone

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1.1: nitric acid; sulfuric acid / dichloromethane / 1 h / 0 °C / pH 7 - 8 2.1: ammonium formate; iron / toluene; water / 103 °C 3.1: sodium methylate / Dimethyl ether / 0.5 h / 20 °C 3.2: 8 h 4.1: trichlorophosphate / toluene / 2 h / Reflux View Scheme
Multi-step reaction with 4 steps 1.1: nitric acid; sulfuric acid / dichloromethane / 2.25 h / 0 °C 2.1: iron; ammonium acetate / toluene; water / 105 °C 3.1: sodium methylate / 1,2-dimethoxyethane / 0.5 h / Inert atmosphere 3.2: Inert atmosphere 4.1: trichlorophosphate / 10 h / Reflux View Scheme
Multi-step reaction with 4 steps 1: nitric acid / dichloromethane / 2 h / -20 - -10 °C 2: 5,5-dimethyl-1,3-cyclohexadiene / 15 h / Reflux 3: iron; acetic acid / 2 h / 60 - 90 °C 4: trichlorophosphate / acetonitrile / 6 h / Reflux View Scheme

: 75665-88-2
1-(4-(benzyloxy)-5-methoxy-2-nitrophenyl)ethanone

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: ammonium formate; iron / toluene; water / 103 °C 2.1: sodium methylate / Dimethyl ether / 0.5 h / 20 °C 2.2: 8 h 3.1: trichlorophosphate / toluene / 2 h / Reflux View Scheme
Multi-step reaction with 3 steps 1.1: iron; ammonium acetate / toluene; water / 105 °C 2.1: sodium methylate / 1,2-dimethoxyethane / 0.5 h / Inert atmosphere 2.2: Inert atmosphere 3.1: trichlorophosphate / 10 h / Reflux View Scheme
Multi-step reaction with 3 steps 1: 5,5-dimethyl-1,3-cyclohexadiene / 15 h / Reflux 2: iron; acetic acid / 2 h / 60 - 90 °C 3: trichlorophosphate / acetonitrile / 6 h / Reflux View Scheme

: 498-02-2
1-(3-methoxy-4-hydroxyphenyl)ethanone

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1.1: potassium carbonate / N,N-dimethyl-formamide / 5 h / 40 °C 2.1: nitric acid; sulfuric acid / dichloromethane / 1 h / 0 °C / pH 7 - 8 3.1: ammonium formate; iron / toluene; water / 103 °C 4.1: sodium methylate / Dimethyl ether / 0.5 h / 20 °C 4.2: 8 h 5.1: trichlorophosphate / toluene / 2 h / Reflux View Scheme
Multi-step reaction with 5 steps 1.1: potassium carbonate / N,N-dimethyl-formamide / 40 °C 2.1: nitric acid; sulfuric acid / dichloromethane / 2.25 h / 0 °C 3.1: iron; ammonium acetate / toluene; water / 105 °C 4.1: sodium methylate / 1,2-dimethoxyethane / 0.5 h / Inert atmosphere 4.2: Inert atmosphere 5.1: trichlorophosphate / 10 h / Reflux View Scheme
Multi-step reaction with 5 steps 1.1: potassium carbonate / N,N-dimethyl-formamide / 0.25 h / 20 °C 1.2: 4 h / 20 °C 2.1: nitric acid / dichloromethane / 2 h / -20 - -10 °C 3.1: 5,5-dimethyl-1,3-cyclohexadiene / 15 h / Reflux 4.1: iron; acetic acid / 2 h / 60 - 90 °C 5.1: trichlorophosphate / acetonitrile / 6 h / Reflux View Scheme

: 205448-28-8
5-{[(3-(benzyloxy)-4-methoxyphenyl)amino]methylene}-2,2-dimethyl-1,3-dioxane-4,6- dione

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: biphenyl / diphenylether / 1 h / 220 °C / Inert atmosphere 2: trichlorophosphate / 5 h / Inert atmosphere; Reflux View Scheme
Multi-step reaction with 2 steps 1: 1,2-dichloro-benzene / 7 h / 180 °C 2: trichlorophosphate / toluene / 1.5 h / 120 °C View Scheme
Multi-step reaction with 2 steps 1: 1,2-dichloro-benzene / 7 h / 180 °C 2: trichlorophosphate / N,N-dimethyl-formamide / 1 h / 100 °C View Scheme

: 1-[2-nitro-4-benzyloxy-5-methoxyphenyl]-3-(dimethylamino)prop-2-en-1-one

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: iron; acetic acid / 2 h / 60 - 90 °C 2: trichlorophosphate / acetonitrile / 6 h / Reflux View Scheme

: 75167-86-1
2-(benzyloxy)-1-methoxy-4-nitrobenzene

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: ammonium chloride; iron / ethanol; water / 1 h / 20 °C / Reflux 2: ethanol / 1 h / Reflux 3: 1,2-dichloro-benzene / 7 h / 180 °C 4: trichlorophosphate / toluene / 1.5 h / 120 °C View Scheme
Multi-step reaction with 4 steps 1: iron / ethanol; water / Reflux 2: ethanol / 1 h / 80 °C 3: 1,2-dichloro-benzene / 7 h / 180 °C 4: trichlorophosphate / N,N-dimethyl-formamide / 1 h / 100 °C View Scheme

: 61324-40-1
3-benzyloxy-4-methoxybenzeneamine

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: ethanol / 1 h / Reflux 2: 1,2-dichloro-benzene / 7 h / 180 °C 3: trichlorophosphate / toluene / 1.5 h / 120 °C View Scheme
Multi-step reaction with 3 steps 1: ethanol / 1 h / 80 °C 2: 1,2-dichloro-benzene / 7 h / 180 °C 3: trichlorophosphate / N,N-dimethyl-formamide / 1 h / 100 °C View Scheme

: 636-93-1
5-nitroguaiacol

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1: potassium carbonate / N,N-dimethyl-formamide / 40 °C 2: ammonium chloride; iron / ethanol; water / 1 h / 20 °C / Reflux 3: ethanol / 1 h / Reflux 4: 1,2-dichloro-benzene / 7 h / 180 °C 5: trichlorophosphate / toluene / 1.5 h / 120 °C View Scheme
Multi-step reaction with 5 steps 1: potassium carbonate / N,N-dimethyl-formamide / 5 h / 90 °C 2: iron / ethanol; water / Reflux 3: ethanol / 1 h / 80 °C 4: 1,2-dichloro-benzene / 7 h / 180 °C 5: trichlorophosphate / N,N-dimethyl-formamide / 1 h / 100 °C View Scheme

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

: 205448-31-3
4-chloro-6-methoxy-7-hydroxyquinoline

Conditions

Conditions	Yield
With methanesulfonic acid; trifluoroacetic acid for 3h; Reflux; Inert atmosphere;	100%
Stage #1: 7-(benzyloxy)-4-chloro-6-methoxyquinoline With methanesulfonic acid; trifluoroacetic acid for 3h; Reflux; Stage #2: With sodium hydroxide for 2h; pH=7;	100%
With trifluoroacetic acid at 75℃; for 6h;	95.4%
With hydrogen bromide; acetic acid In water at 80℃; for 3h;	80%

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

: 52671-64-4
4-Amino-3-chlorophenol hydrochloride

: 286371-53-7
4-{[7-(Benzyloxy)-6-methoxy-4-quinolyl]oxy}-2-chloroaniline

Conditions

Conditions	Yield
With sodium hydride; potassium carbonate In N,N-dimethyl-formamide; mineral oil at 100℃; for 2h; Inert atmosphere;	98%
With dimethyl sulfoxide In methanol; water	66%

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

: 516526-32-2
4-(7-benzyloxy-6-methoxyquinolin-4-yloxy)aniline

Conditions

Conditions	Yield
Stage #1: 4-amino-phenol With sodium methylate In methanol; ISOPROPYLAMIDE at 20℃; for 1h; Stage #2: 7-(benzyloxy)-4-chloro-6-methoxyquinoline In ISOPROPYLAMIDE at 120℃; for 22h;	96%
Multi-step reaction with 2 steps 1.1: 1-methyl-pyrrolidin-2-one / 2 h / 150 °C 2.1: hydrogenchloride; methanol; water / 6 h / Heating / reflux 2.2: pH 12 View Scheme
Multi-step reaction with 2 steps 1: N-ethyl-N,N-diisopropylamine / 5,5-dimethyl-1,3-cyclohexadiene / 140 °C / Inert atmosphere 2: iron; ammonium chloride / ethanol; water / 2 h / 90 °C / Inert atmosphere View Scheme

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

: 403-19-0
2-fluoro-4-nitrophenol

: 479690-03-4
7-benzyloxy-4-(2-fluoro-4-nitro-phenoxy)-6-methyloxyquinoline

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In chlorobenzene at 140℃; for 18h;	92%
With N-ethyl-N,N-diisopropylamine In chlorobenzene for 48h; Reflux;	82%
With N-ethyl-N,N-diisopropylamine In 5,5-dimethyl-1,3-cyclohexadiene at 140℃;	81%

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

: ethyl 1-[(3-fluoro-4-hydroxyphenyl)carbamoyl]cyclopropane-1-carboxylate

: ethyl 1-[[3-fluoro-4-[[6-methoxy-7-benzyloxyquinolin-4-yl]oxy]phenyl]carbamoyl]cyclopropane-1-carboxylate

Conditions

Conditions	Yield
With dmap at 160℃; for 4h;	90.5%

: 100-02-7
4-nitro-phenol

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

: 417725-03-2
7-(benzyloxy)-6-methoxy-4-(4-nitrophenoxy)quinoline

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In xylene for 12h; Reflux;	84.3%
In chlorobenzene for 16h; Reflux;	62.4%
In chlorobenzene for 20h; Reflux;	201.8 g

: 649736-31-2
1-(2-fluoro-3-hydroxy-6-nitrophenyl)propan-2-one

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

: 1210828-42-4
1-(3-(7-(benzyloxy)-6-methoxyquinolin-4-yloxy)-2-fluoro-6-nitrophenyl)propan-2-one

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In 1-methyl-pyrrolidin-2-one at 100℃;	84%

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

: 394-41-2
3-fluoro-4-nitrophenol

: 286371-58-2
7-(benzyloxy)-4-(3-fluoro-4-nitrophenoxy)-6-methoxyquinoline

Conditions

Conditions	Yield
In chlorobenzene at 120℃; for 21h;	82%
Stage #1: 7-(benzyloxy)-4-chloro-6-methoxyquinoline; 3-fluoro-4-nitrophenol In chlorobenzene at 120℃; for 21h; Stage #2: With sodium hydroxide In chloroform; water; chlorobenzene at 20℃;	82%
With N-ethyl-N,N-diisopropylamine In chlorobenzene at 140℃; for 15h;	50%
With sodium hydroxide In chloroform; chlorobenzene	47%
In chlorobenzene for 16h; Reflux;

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

: 100-68-5
methyl-phenyl-thioether

: 205448-31-3
4-chloro-6-methoxy-7-hydroxyquinoline

Conditions

Conditions	Yield
With sodium hydroxide; methanesulfonic acid In hexane; trifluorormethanesulfonic acid	75%

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

: 399-96-2
4-amino-2-fluorophenol

: 479690-04-5
4-(7-(benzyloxy)-6-methoxyquinolin-4-yloxy)-3-fluorobenzenamine

Conditions

Conditions	Yield
Stage #1: 4-amino-2-fluorophenol With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 0.5h; Inert atmosphere; Stage #2: 7-(benzyloxy)-4-chloro-6-methoxyquinoline In N,N-dimethyl-formamide; mineral oil at 100℃; for 30h;	73%

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

: 849217-56-7
N-(3-fluoro-4-hydroxyphenyl)-N'-(2-phenylethyl)ethanediamide

: N-{4-[(7-benzyloxy-6-methoxyquinolin-4-yl)oxy]-3-fluorophenyl}-N'-(2-phenylethyl)ethanediamide

Conditions

Conditions	Yield
With dmap; bromobenzene for 6h; Heating / reflux;	61%
With dmap In bromobenzene for 6h; Heating / reflux;	61%

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

: 1849-36-1
para-nitrobenzenethiol

: 7-(benzyloxy)-6-methoxy-4-((4-nitrophenyl)thio)quinoline

Conditions

Conditions	Yield
In chlorobenzene for 16h; Reflux;	60.1%

: 847802-91-9
6-hydroxy-N-methyl-1-naphthalenecarboxamide

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

: 1058137-70-4
6-(7-(benzyloxy)-6-methoxyquinolin-4-yloxy)-N-methyl-1-naphthamide

Conditions

Conditions	Yield
With copper(l) iodide; caesium carbonate In N,N-dimethyl-formamide; acetylacetone at 120℃; for 24h; Reagent/catalyst; Solvent; Temperature; Time; Concentration;	58%
With dmap In 1,4-dioxane for 72h; Product distribution / selectivity; Heating / reflux;

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

: 554-84-7
meta-nitrophenol

: C23H18N2O5

Conditions

Conditions	Yield
In chlorobenzene for 16h; Reflux;	52.4%
In chlorobenzene for 18h; Reflux;

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

: 3096-71-7
2,5-dimethyl-4-amino phenol

: 286371-50-4
4-{[7-(Benzyloxy)-6-methoxy-4-quinolyl]oxy}-2,5-dimethylaniline

Conditions

Conditions	Yield
With dimethyl sulfoxide In methanol; water	52%

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

: 3096-69-3
4-amino-2,3-dimethylphenol

: 144-55-8
sodium hydrogencarbonate

: 286371-56-0
4-{[7-(Benzyloxy)-6-methoxy-4-quinolyl]oxy}-2,3-dimethylaniline

Conditions

Conditions	Yield
With dimethyl sulfoxide	49%

...Expand

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

: 666735-37-1
2-phenyl-[1,8]naphthyridin-3-ol

: 3-(7-benzyloxy-6-methoxy-quinolin-4-yloxy)-2-phenyl-[1,8]naphthyridine

Conditions

Conditions	Yield
With dmap In 1,2-dichloro-benzene at 140℃; for 20h;	42%

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

: 1149370-96-6
3,4-dihydro-2H-benzo[b][1,4]oxazin-7-ol hydrochloride

: 1149370-97-7
7-(7-(benzyloxy)-6-methoxyquinolin-4-yloxy)-3,4-dihydro-2H-benzo[b][1,4]oxazine

Conditions

Conditions	Yield
With caesium carbonate In N,N-dimethyl-formamide at 80℃; for 109h;	40.5%

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

: 98902-53-5
thiophene-2-carboxylic acid (4-hydroxy-phenyl)-amide

: 914490-48-5
thiophene-2-carboxylic acid [4-(7-benzyloxy-6-methoxy-quinolin-4-yloxy)-phenyl]-amide

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 140℃; for 5h;	36%

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

: 15457-50-8
p-benzoylaminophenol

: 914200-89-8
N-[4-(7-benzyloxy-6-methoxy-quinolin-4-yloxy)-phenyl]-benzamide

Conditions

Conditions	Yield
at 140℃; for 3h;	32%
at 140℃; for 3h; Product distribution / selectivity;	32%
at 140℃; for 3h;	32%
In N,N-dimethyl-formamide at 145℃; for 7h; Product distribution / selectivity;	28%

: 288385-88-6
4-fluoro-2-methyl-1H-indol-5-ol

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

: 1210828-43-5
7-(benzyloxy)-4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxyquinoline

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 20 - 100℃; for 16h; Inert atmosphere;	27%
With dmap In 1,4-dioxane for 72h; Reflux;

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

: 6420-90-2
2-(4-hydroxyphenyl)-1-phenylethan-1-one

: 914490-65-6
2-[4-(7-benzyloxy-6-methoxy-quinolin-4-yloxy)-phenyl]-1-phenyl-ethanone

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 145℃; for 5h;	21%

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

: 15267-98-8
sodium 4-aminophenolate

: 516526-32-2
4-(7-benzyloxy-6-methoxyquinolin-4-yloxy)aniline

Conditions

Conditions	Yield
In ISOPROPYLAMIDE at 120℃; for 22h;

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

: 103-90-2
4-acetaminophenol

: 914490-52-1
N-[4-(7-benzyloxy-6-methoxy-quinolin-4-yloxy)-phenyl]-acetamide

Conditions

Conditions	Yield
In 1-methyl-pyrrolidin-2-one at 150℃; for 2h;

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

: 2437-17-4
6-hydroxy-1-naphthoic acid

: 1044676-75-6
6-(7-(benzyloxy)-6-methoxyquinolin-4-yloxy)-1-naphthoic acid

Conditions

Conditions	Yield
With potassium hydroxide In dimethyl sulfoxide at 130℃; for 5h;

: 1953-54-4
indol-5-ol

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

: 1058157-84-8
C25H20N2O3

Conditions

Conditions	Yield
With dmap In 1,4-dioxane for 72h; Heating / reflux;

: 5192-03-0
5-amino-1H-indole

: 286371-49-1
7-(benzyloxy)-4-chloro-6-methoxyquinoline

: 1058157-22-4
4-(1H-indol-5-ylamino)-7-benzyloxy-6-methoxy-quinoline

Conditions

Conditions	Yield
In isopropyl alcohol for 1h; Heating / reflux;

Product Name

7-Benzyloxy-4-chloro-6-methoxy-quinoline

Synthetic route

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