Benzoylformic acid supplier

Name
Benzoylformic acid
EINECS 210-278-7
CAS No. 611-73-4
Article Data360
CAS DataBase
Density 1.298 g/cm³
Solubility methanol: 0.1 g/mL, clear
Melting Point 60-69 °C
Formula C₈H₆O₃
Boiling Point 258.6 °C at 760 mmHg
Molecular Weight 150.134
Flash Point 124.4 °C
Transport Information
Appearance white to light yellow adhering crystals
Safety 26-28-36-28A-24-22
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms Glyoxylicacid, phenyl- (6CI,7CI,8CI);2-Oxo-2-phenylacetic acid;2-Oxo-2-phenylethanoicacid;Benzoylformic acid;CAA 0869;Formic acid, benzoyl-;LFC 1849;NSC 28293;Oxophenylacetic acid;Phenylgloxylic acid;Phenylglyoxylic acid;Phenyloxoacetic acid;a-Ketophenylacetic acid;a-Oxobenzeneacetic acid;
PSA 54.37000
LogP 0.95390

Synthetic route

: 15206-55-0
methyl 2-oxo-2-phenylacetate

: 611-73-4
Benzoylformic acid

Conditions

Conditions	Yield
With water; sodium hydroxide	100%
With water; sodium hydroxide In dichloromethane	100%
With water; sodium hydroxide at 20℃; for 2h;	99.2%

: 7332-98-1
tert-butyl phenylglyoxylate

: 611-73-4
Benzoylformic acid

Conditions

Conditions	Yield
With trifluoroacetic acid In dichloromethane at 20℃;	100%
With trifluoroacetic acid at 0℃; for 1h;	57%
With trifluoroacetic acid at 0℃; for 5h;

: 94-41-7
benzalacetophenone

A: 611-73-4
Benzoylformic acid

B: 65-85-0
benzoic acid

Conditions

Conditions	Yield
With methyl 3,5-bis((1H-1,2,4-triazol-1-yl)methyl)benzoate; oxygen; sodium acetate; nickel dibromide at 120℃; under 760.051 - 912.061 Torr; for 48h; chemoselective reaction;	A 91% B 99%
Multi-step reaction with 2 steps 1: sodium hydrogencarbonate; ruthenium trichloride; potassium peroxymonosulfate / acetonitrile; water; ethyl acetate / 0.3 h 2: iron(II) perchlorate hexahydrate; tetramethylammonium hydroxide pentahydrate / acetonitrile; water / 12 h / Inert atmosphere View Scheme

: 611-71-2, 611-72-3, 17199-29-0, 90-64-2
MANDELIC ACID

: 611-73-4
Benzoylformic acid

Conditions

Conditions	Yield
With sodium bromate In acetonitrile for 52h; Heating;	98%
With oxalyl dichloride; methyl dodecyl sulfoxide; triethylamine In dichloromethane at -60 - 20℃; Swern oxidation;	96%
With oxalyl dichloride; methyl dodecyl sulfoxide; triethylamine In dichloromethane at -60 - 20℃; Swern oxidation;	96%

: 1352131-39-5
5-hydroxy-N,N',5-triphenylimidazolidine-2,4-dione

: 611-73-4
Benzoylformic acid

Conditions

Conditions	Yield
With water; sodium hydroxide In methanol at 20 - 50℃; for 1h;	98%

: 825-52-5
2-(hydroxyimino)-2-phenylacetonitrile

: 611-73-4
Benzoylformic acid

Conditions

Conditions	Yield
With sulfuric acid at 100 - 120℃; for 5h;	96.6%

: 93-56-1
phenylethane 1,2-diol

: 611-73-4
Benzoylformic acid

Conditions

Conditions	Yield
With tert.-butylhydroperoxide; iron(III) chloride; thymidyl acetic acid In decane; acetonitrile at 80℃; for 6h;	96%
With Oxone; 2-Iodobenzoic acid In water; acetonitrile at 70℃; for 6h;	94%
With sodium tetrahydroborate; 1% Pd/C; water; potassium hydroxide In methanol at 20℃; for 15h; In air;	91%
With potassium permanganate; acetic acid; Tris(3,6-dioxaheptyl)amine In dichloromethane for 4h; Ambient temperature;	71%
aqua(2,2'-bipyridine)(2,2':6',2''-terpyridine)ruthenium(II)(2+) In phosphate buffer for 6h; pH=7.2; Electrolysis;	47%

: 2425-28-7
2-Bromo-1-phenylethanol

: 611-73-4
Benzoylformic acid

Conditions

Conditions	Yield
With tetramethoxytitanium; β-Propiolactone at 60℃; for 2h; Temperature;	96%
Multi-step reaction with 5 steps 1.1: hydrogen bromide; dihydrogen peroxide / water / 4.5 h / 25 - 90 °C 2.1: toluene-4-sulfonic acid; benzene / water / 36 h / 85 °C 3.1: tetrabutylammomium bromide; sodium ethanolate / water / 23 h / 105 °C 4.1: oxalic acid / dichloromethane; water / 5 h / 25 °C 5.1: tetrabutylammomium bromide; hydrogen bromide / water / 0.02 h 5.2: 5 h / 25 - 90 °C View Scheme

Yield

With tetramethoxytitanium; β-Propiolactone at 60℃; for 2h; Temperature;

96%

Multi-step reaction with 5 steps
1.1: hydrogen bromide; dihydrogen peroxide / water / 4.5 h / 25 - 90 °C
2.1: toluene-4-sulfonic acid; benzene / water / 36 h / 85 °C
3.1: tetrabutylammomium bromide; sodium ethanolate / water / 23 h / 105 °C
4.1: oxalic acid / dichloromethane; water / 5 h / 25 °C
5.1: tetrabutylammomium bromide; hydrogen bromide / water / 0.02 h
5.2: 5 h / 25 - 90 °C
View Scheme

: 2-hydroxy-4-methyl-2-phenylmorpholin-3-one

: 611-73-4
Benzoylformic acid

Conditions

Conditions	Yield
With hydrogenchloride for 2h; Heating;	94%

: 611-71-2
(R)-Mandelic Acid

: 611-73-4
Benzoylformic acid

Conditions

Conditions	Yield
With phosphotungstic acid; ferric nitrate at 55 - 60℃; for 0.166667h;	93%
With D-lactate oxidase from Gluconobacter oxydans 621H; oxygen; catalase In aq. buffer at 30℃; pH=7.4; Reagent/catalyst; Enzymatic reaction;
With NAD at 30℃; for 48h; pH=9.5; Kinetics; Reagent/catalyst; Temperature; pH-value; Enzymatic reaction;

Na2S2O3·5H2O: Na2S2O3·5H2O

: 611-71-2, 611-72-3, 17199-29-0, 90-64-2
MANDELIC ACID

: 611-73-4
Benzoylformic acid

Conditions

Conditions	Yield
With hydrogenchloride; sodium hypobromide; sodium thiosulfate In dichloromethane; water	91%

: 582-24-1
1-phenyl-2-hydroxyethanone

: 611-73-4
Benzoylformic acid

Conditions

Conditions	Yield
With hydrogen bromide; dihydrogen peroxide In water at 25 - 65℃; for 5h; Reagent/catalyst; Time;	90.1%
With hydrogen bromide; dihydrogen peroxide In water Temperature; Reflux;	79.3%
Stage #1: 1-phenyl-2-hydroxyethanone With tetrabutylammomium bromide; hydrogen bromide In water for 0.0166667h; Stage #2: With dihydrogen peroxide In water at 25 - 90℃; for 5h;	83 %Chromat.
With hydrogen bromide; dihydrogen peroxide In water at 90℃; for 7h;

: 80490-41-1
3,4-diphenyl-4-hydroxy-2-isoxazolin-5-one

A: 100-47-0
benzonitrile

B: 611-73-4
Benzoylformic acid

Conditions

Conditions	Yield
With triethylamine In benzene for 3h; Heating;	A n/a B 89.3%
With hydrogenchloride; sodium hydroxide; water Mechanism;

: 134918-42-6
epoxide of α,β-difluoro-β-chlorostyrene

: 611-73-4
Benzoylformic acid

Conditions

Conditions	Yield
With sodium hydrogencarbonate for 0.5h;	89%

: 98-86-2
acetophenone

: 611-73-4
Benzoylformic acid

Conditions

Conditions	Yield
With pyridine; selenium(IV) oxide at 120℃; for 18h; Inert atmosphere;	87%
With pyridine; selenium(IV) oxide for 3h; Reflux;	87%
With pyridine; selenium(IV) oxide at 90℃; for 5h; Inert atmosphere;	87%

: 2835-06-5
phenylglycin

: 611-73-4
Benzoylformic acid

Conditions

Conditions	Yield
With potassiuim nitrosodisulfonate In water for 60h; pH 10.0;	82%
With ω-transaminase

: 130749-19-8
2,2,2-Tris-benzotriazol-1-yl-1-phenyl-ethanone

: 611-73-4
Benzoylformic acid

Conditions

Conditions	Yield
With sulfuric acid In tetrahydrofuran at 50℃; for 48h;	81%

: 79344-05-1
3,5-diphenyl-4,4-dichloro-5-hydroxy-Δ2-isoxazoline

A: 100-47-0
benzonitrile

B: 611-73-4
Benzoylformic acid

Conditions

Conditions	Yield
With potassium hydroxide In water for 2.5h; Heating;	A 75.4% B 80%

: 1074-12-0
phenylglyoxal hydrate

: 611-73-4
Benzoylformic acid

Conditions

Conditions	Yield
Stage #1: phenylglyoxal hydrate With silver perchlorate; sodium hydroxide In water at 20℃; Inert atmosphere; Stage #2: With hydrogenchloride In water Inert atmosphere;	78%
bei der Einw. von gaerender Hefe;
Multi-step reaction with 2 steps 1: 26.5 percent Spectr. / Et3N, pyridine, O2, 3-Angstroem sieves / Cu(NO3)2py2 / methanol / 12 h / 25 °C / 1748 Torr 2: 68.6 percent Spectr. / Et3N, pyridine, O2, H2O / Cu(NO3)2py2 / methanol / 12 h / 25 °C / 1748 Torr View Scheme

: 124-38-9
carbon dioxide

: 93-89-0
benzoic acid ethyl ester

: 611-73-4
Benzoylformic acid

Conditions

Conditions	Yield
With chloro-trimethyl-silane; magnesium In N,N-dimethyl-formamide at 20℃; Temperature; Solvent;	75%

: 532-54-7
oxo-phenyl-acetaldehyde oxime

: 611-73-4
Benzoylformic acid

Conditions

Conditions	Yield
With hydrogenchloride; water; sodium nitrite at 80℃; for 4h;	73.5%
With acetic anhydride bei der Destillation u. Verseifen mit Salzsaeure;

: 124-38-9
carbon dioxide

: 100-52-7
benzaldehyde

: 611-73-4
Benzoylformic acid

Conditions

Conditions	Yield
Stage #1: carbon dioxide; benzaldehyde With potassium cyanide In N,N-dimethyl-formamide at 12℃; for 1h; Schlenk technique; Stage #2: With titanium(IV)isopropoxide; 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 40℃; for 18h; Schlenk technique;	72%

: 2461-80-5
diphenacyl sulfide

A: 1522397-30-3
C16H10O4S

B: 595565-17-6
(3-phenylthiophene-2,5-diyl)bis(phenylmethanone)

C: 611-73-4
Benzoylformic acid

Conditions

Conditions	Yield
With selenium(IV) oxide In 1,4-dioxane for 2h; Reflux;	A n/a B 10% C 71%

...Expand

: 80490-51-3
4-hydroxy-3-methyl-4-phenylisoxazoline-5-one

A: 611-73-4
Benzoylformic acid

B: 75-05-8
acetonitrile

Conditions

Conditions	Yield
With 2,6-dichloro-benzonitrile In benzene for 0.5h; Heating;	A 70% B n/a

: 93-58-3
benzoic acid methyl ester

: 124-38-9
carbon dioxide

: 611-73-4
Benzoylformic acid

Conditions

Conditions	Yield
With chloro-trimethyl-silane; magnesium In N,N-dimethyl-formamide at 20℃;	69%

: 614-21-1
2-nitroacetophenone

A: 611-73-4
Benzoylformic acid

B: 65-85-0
benzoic acid

C: 6635-54-7
3,4-dibenzoyl-1,2,5-oxadiazole-N-oxide

Conditions

Conditions	Yield
With nitric acid; sodium nitrite In nitromethane; water at 60℃; for 0.5h;	A 9.7% B 4.4% C 68.4%
With nitric acid; sodium nitrite In nitromethane; water at 60℃; for 0.5h; Product distribution; Mechanism; variation of solvents, reactants;	A 9.7% B 4.4% C 68.4%

...Expand

: 591-50-4
iodobenzene

: 201230-82-2
carbon monoxide

A: 611-71-2, 611-72-3, 17199-29-0, 90-64-2
MANDELIC ACID

B: 611-73-4
Benzoylformic acid

C: 65-85-0
benzoic acid

Conditions

Conditions	Yield
With methyl iodide; sodium tetrahydroborate In 1,4-dioxane; water at 20℃; for 20h;	A 3% B 68% C 5%
With methyl iodide; sodium tetrahydroborate In 1,4-dioxane; water at 20℃; for 20h;	A 3% B 64% C 13%
With calcium hydroxide; water; dichlorobis(dimethylphenylphosphine)palladium(II) In isopropyl alcohol at 100℃; for 12h; P(CO) = 150 atm at room temperature; further catalysts, solvents and hydroxide;	A 69.0 % Chromat. B 3.8 % Chromat. C 9.3 % Chromat.
With calcium hydroxide; water; bis(benzonitrile)palladium(II) dichloride In isopropyl alcohol at 100℃; for 12h; P(CO) = 150 atm at room temperature; further catalysts, solvents and hydroxide;	A 46.0 % Chromat. B 8.7 % Chromat. C 25.5 % Chromat.
With sodium sulfide; CoCl2 In 1,4-dioxane; water at 20℃; for 20h; Product distribution; other reag.; other solvent;	A 3 % Chromat. B 62 % Chromat. C 5 % Chromat.

...Expand

: 536-74-3
phenylacetylene

A: 103-82-2
phenylacetic acid

B: 611-73-4
Benzoylformic acid

Conditions

Conditions	Yield
With dihydrogen peroxide; methyltrioxorhenium(VII) In dichloromethane for 48h;	A 21% B 68%
With dihydrogen peroxide; methyltrioxorhenium(VII) In acetone for 48h;	A 65% B 11%

: 3708-04-1
2-methylsulfonyl-1-phenylethanone

A: 611-73-4
Benzoylformic acid

B: 65-85-0
benzoic acid

Conditions

Conditions	Yield
With ammonium cerium (IV) nitrate; oxygen In acetonitrile at 60℃;	A 26% B 65%

: 611-71-2, 611-72-3, 17199-29-0, 90-64-2
MANDELIC ACID

A: 611-73-4
Benzoylformic acid

B: 65-85-0
benzoic acid

Conditions

Conditions	Yield
With oxone; 2-iodo-3,4,5,6-tetramethylbenzoic acid In water; acetonitrile at 20℃; for 3h;	A 63% B 30%

: 611-73-4
Benzoylformic acid

: 25726-04-9
phenylglyoxylyl chloride

Conditions

Conditions	Yield
With Dichloromethyl methyl ether at 50℃; for 0.5h;	100%
With Dichloromethyl methyl ether In dichloromethane at 15 - 20℃; for 1h; Inert atmosphere;	100%
With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane	95%

: 123-75-1
pyrrolidine

: 611-73-4
Benzoylformic acid

: 15563-45-8
1-thiobenzoylpyrrolidine

Conditions

Conditions	Yield
With sulfur In benzene at 80℃; for 0.166667h;	100%
With sulfur In benzene for 0.166667h; Heating;	100%

: 110-89-4
piperidine

: 611-73-4
Benzoylformic acid

: 15563-40-3
N-thiobenzoylpiperidine

Conditions

Conditions	Yield
With sulfur In benzene at 80℃; for 0.75h;	100%
With sulfur In benzene at 80℃; for 1h;

: 110-91-8
morpholine

: 611-73-4
Benzoylformic acid

: 2032-36-2
Thiobenzmorpholid

Conditions

Conditions	Yield
With sulfur In benzene at 80℃; for 0.75h;	100%

: 290-37-9
1,4-pyrazine

: 611-73-4
Benzoylformic acid

: 3430-09-9
phenyl(pyrazin-2-yl)methanone

Conditions

Conditions	Yield
With NH4S2O8; sulfuric acid; silver nitrate In dichloromethane; water at 40℃; for 2.5h;	100%
Stage #1: 1,4-pyrazine; Benzoylformic acid With ammonium peroxydisulfate; sulfuric acid; silver nitrate In dichloromethane; water at 50℃; for 2h; Stage #2: With water; sodium hydrogencarbonate In dichloromethane	91%
With ferrous(II) sulfate heptahydrate; ammonium peroxydisulfate; formic acid; dimethyl sulfoxide In dichloromethane; water at 40℃; Minisci Aromatic Substitution;	74%
With ammonium peroxydisulfate; silver nitrate; trifluoroacetic acid In dichloromethane; water at 60℃; for 3h;	68%
With dipotassium peroxodisulfate; silver orthophosphate In dichloromethane; water at 40℃; for 24h;	26%

: 1122-54-9
methyl (4-pyridyl) ketone

: 611-73-4
Benzoylformic acid

: 132883-96-6
1-(2-benzoylpyridin-4-yl)-ethanone

Conditions

Conditions	Yield
With NH4S2O8; sulfuric acid; silver nitrate In dichloromethane; water at 40℃; for 2.5h;	100%
	33%

: 100-48-1
pyridine-4-carbonitrile

: 611-73-4
Benzoylformic acid

: 2-benzoylisonicotinonitrile

Conditions

Conditions	Yield
With NH4S2O8; sulfuric acid; silver nitrate In dichloromethane; water at 40℃; for 2.5h;	100%

: 91-19-0
2,3-diethynylquinoxaline

: 611-73-4
Benzoylformic acid

: 13481-33-9
phenyl(quinoxalin-2-yl)methanone

Conditions

Conditions	Yield
With NH4S2O8; sulfuric acid; silver nitrate In dichloromethane; water at 40℃; for 2.5h;	100%
With dipotassium peroxodisulfate In water; acetonitrile at 20 - 37℃; for 15h; Irradiation; Green chemistry; regioselective reaction;	80%
With dipotassium peroxodisulfate; silver orthophosphate In dichloromethane; water at 40℃; for 24h;	58%

: 3326-71-4
2-furoic acid hydrazide

: 611-73-4
Benzoylformic acid

: [(Furan-2-carbonyl)-hydrazono]-phenyl-acetic acid

Conditions

Conditions	Yield
	100%

: 91-21-4
1,2,3,4-tetrahydroisoquinoline

: 611-73-4
Benzoylformic acid

: 122709-96-0
(3,4-dihydroisoquinoline-2(1H)-yl)(phenyl)methanethione

Conditions

Conditions	Yield
With sulfur In benzene at 80℃; for 0.25h;	100%
With sulfur In benzene at 80℃; for 0.25h;

: 611-73-4
Benzoylformic acid

: 100-46-9
benzylamine

: 780-25-6
N-benzylidene benzylamine

Conditions

Conditions	Yield
In dichloromethane at 40℃; for 3h;	100%

: 79-37-8
oxalyl dichloride

: 611-73-4
Benzoylformic acid

: 124-02-7
diallylamine

: 1-phenyl-2-(diallylamino)ethane-1,2-dione

Conditions

Conditions	Yield
Stage #1: oxalyl dichloride; Benzoylformic acid With copper diacetate; N,N-dimethyl-formamide In dichloromethane at 20℃; for 2h; Stage #2: diallylamine With triethylamine In dichloromethane	100%

...Expand

: 64868-20-8
(1S,2R)-(1-methyl-2-phenyl-2-hydroxy)ethyltrimethylammonium iodide

: 611-73-4
Benzoylformic acid

: 1639366-24-7
[(1R,2S)-N,N-dimethylephedrinium][phenylglyoxylate]

Conditions

Conditions	Yield
With Dowex Inert atmosphere;	100%

: 1829-26-1
1-acetoxy-1,2-benziodoxol-3-one

: 611-73-4
Benzoylformic acid

: C15H9IO5

Conditions

Conditions	Yield
In chloroform for 0.5h; Inert atmosphere; Reflux;	100%
In chloroform for 0.5h; Inert atmosphere; Reflux;	100%

: 3699-54-5
2-oxo-imidazolidine-1-ethanol

: 611-73-4
Benzoylformic acid

: PhGA-HEI

Conditions

Conditions	Yield
In water; acetone	100%

: 4-hydrazino-quinazoline

: 611-73-4
Benzoylformic acid

: phenyl[(3H-quinazolin-4-ylidene)hydrazono]acetic acid

Conditions

Conditions	Yield
In isopropyl alcohol for 1h; Heating;	99.2%

: 611-73-4
Benzoylformic acid

: 103-82-2
phenylacetic acid

Conditions

Conditions	Yield
With chlorobenzene In methanol at 40℃; for 5h; Sealed tube; Green chemistry; chemoselective reaction;	99%
With phosphonic Acid; methanesulfonic acid; sodium iodide In water at 95℃; for 48h; Inert atmosphere;	94.3%
With hydrazine hydrate anschliessend Erhitzen mit KOH;
With phosphorus; hydrogen iodide at 160℃;

: 65253-04-5
(-)-8-phenylmenthol

: 611-73-4
Benzoylformic acid

: 88002-15-7
Phenylglyoxylsaeure-<(1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)-1-cyclohexyl>ester

Conditions

Conditions	Yield
With toluene-4-sulfonic acid In toluene Heating;	99%
With toluene-4-sulfonic acid In toluene at 130℃; for 2h; Dean-Stark;	25%
With hydrogen cation

: 6638-79-5
N,O-dimethylhydroxylamine*hydrochloride

: 611-73-4
Benzoylformic acid

: 141694-25-9
N-methoxy-N-methyl-α-oxo-benzeneacetamide

Conditions

Conditions	Yield
With 4-methyl-morpholine; 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride In acetonitrile at 20℃; for 1.5h;	99%
Stage #1: Benzoylformic acid With N-Bromosuccinimide; triphenylphosphine In dichloromethane at 0℃; for 0.25h; Stage #2: N,O-dimethylhydroxylamine*hydrochloride With triethylamine In dichloromethane at 20℃; for 1h; chemoselective reaction;	75%
With 2-chloro-1-methyl-pyridinium iodide; triethylamine In dichloromethane for 0.75h; Heating;	53%

: 611-73-4
Benzoylformic acid

: 415919-99-2
(1R,2R)-1,2-diphenyl-2-(4-trifluoromethylbenzyloxy)ethanol

: 415920-05-7
(1R,2R)-1,2-diphenyl-2-(4-trifluoromethylbenzyloxy)ethyl phenylglyoxylate

Conditions

Conditions	Yield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 25℃;	99%

: 866457-05-8
(1R,2S)-2-(1,1-dimethylethoxy)-1,2-diphenylethanol

: 611-73-4
Benzoylformic acid

: 866457-10-5
oxophenylacetic acid (1R,2S)-2-(1,1-dimethylethoxy)-1,2-diphenylethyl ester

Conditions

Conditions	Yield
With dmap; diisopropyl-carbodiimide In dichloromethane at 20℃;	99%
With dmap; diisopropyl-carbodiimide In dichloromethane at 20℃;

: 916525-75-2
(1R,2S)-1-(2-methoxyethoxy)-1,2-bis-(2-methoxyphenyl)-ethanol

: 611-73-4
Benzoylformic acid

: 916525-80-9
oxophenylacetic acid (1R,2S)-2-(2-methoxyethoxy)-1,2-bis(2-methoxyphenyl)ethyl ester

Conditions

Conditions	Yield
With dmap; diisopropyl-carbodiimide In dichloromethane at 20℃; for 12h;	99%
With dmap; diisopropyl-carbodiimide In dichloromethane at 20℃; for 12h;

: 15022-08-9
diallylcarbonate

: 611-73-4
Benzoylformic acid

: 35660-91-4, 35845-66-0, 495-41-0
(E)-1-phenyl-2-buten-1-one

Conditions

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0); Tri(p-tolyl)phosphine In 1,4-dioxane at 100℃; for 12h; Inert atmosphere;	99%

: 611-73-4
Benzoylformic acid

: 137-06-4
2-thiocresol

: S-(o-tolyl) benzothioate

Conditions

Conditions	Yield
With dipotassium peroxodisulfate In water; acetonitrile at 70℃; for 24h; Inert atmosphere; Schlenk technique; Sealed tube;	99%
With ammonium peroxydisulfate; copper(II) oxide In water; dimethyl sulfoxide at 80℃; for 12h;	73%

: 106-45-6
para-thiocresol

: 611-73-4
Benzoylformic acid

A: 103-19-5
di(p-tolyl) disulfide

B: 10371-42-3
S-(4-methylphenyl) thiobenzoate

Conditions

Conditions	Yield
With dipotassium peroxodisulfate In water; acetonitrile at 70℃; for 24h; Inert atmosphere; Schlenk technique; Sealed tube;	A 5.5% B 99%

...Expand

: 106-45-6
para-thiocresol

: 611-73-4
Benzoylformic acid

: 10371-42-3
S-(4-methylphenyl) thiobenzoate

Conditions

Conditions	Yield
With dipotassium peroxodisulfate In water; acetonitrile at 70℃; for 24h; Reagent/catalyst; Temperature; Solvent; Inert atmosphere; Schlenk technique; Sealed tube;	99%

: 100-63-0
phenylhydrazine

: 611-73-4
Benzoylformic acid

: 74470-05-6
phenyl-((Z)-phenylhydrazono)-acetic acid

Conditions

Conditions	Yield
With acetic acid In ethanol for 3h; Reflux;	99%

Benzoylformic acid Chemical Properties

The molecular formula of Benzoylformic acid(611-73-4) is and its formula weight is .
The density of Benzoylformic acid(611-73-4) is 1.38 and it has a melting point of 62-65 °C(lit.). The boiling point is 84 °C0.1 mm Hg. Its flash point is 147-151°C/12mm.
The chemical synonyms of Benzoylformic acid(611-73-4) are PHENYLGLYOXYLIC ACID;OXO(PHENYL)ACETIC ACID;RARECHEM AL BO 0070;2-Oxo-2-phenylacetic acid;alpha-Ketophenylacetic acid;alpha-ketophenylaceticacid;alpha-oxo-benzeneaceticaci;alpha-oxobenzeneaceticacid
The molecular structure of Benzoylformic acid(611-73-4):

Benzoylformic acid Toxicity Data With Reference

ivn-mus LD50:180 mg/kg

CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) NX#04110 .

Benzoylformic acid Safety Profile

A poison by intravenous route. When heated to decomposition it emits acrid smoke and irritating vapors.
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-28-36-28A-24-22
WGK Germany 3
RTECS DA1480000
HS Code 29183000

Benzoylformic acid Specification

Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Incompatible materials, strong oxidants.
Incompatibilities with Other Materials Strong oxidizing agents, strong reducing agents, strong acids, strong bases.
Hazardous Decomposition Products Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization Has not been reported.

Product Name

Benzoylformic acid

Synthetic route

Benzoylformic acid Chemical Properties

Benzoylformic acid Toxicity Data With Reference

Benzoylformic acid Safety Profile

Benzoylformic acid Specification

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