D(-)-Arginine supplier | CasNO.157-06-2

Name
D(-)-Arginine
EINECS 205-866-5
CAS No. 157-06-2
Article Data26
CAS DataBase
Density 1.46 g/cm³
Solubility soluble in water
Melting Point 226 °C (dec.)(lit.)
Formula C₆H₁₄N₄O₂
Boiling Point 409.1 °C at 760 mmHg
Molecular Weight 174.203
Flash Point 201.2 °C
Transport Information
Appearance white to light yellow crystal powder
Safety 26-36
Risk Codes 36-36/37/38-20/21/22
Molecular Structure
Hazard Symbols Xi
Synonyms Arginine,D- (8CI);(R)-Arginine;D-2-Amino-5-guanidinovalerate;(2R)-2-amino-5-(carbamimidamido)pentanoic acid;
PSA 125.22000
LogP 0.55280

Synthetic route

: 2389-86-8
(2R)-2-acetamido-5-guanidino-pentanoate

: 157-06-2
D-arginine

Conditions

Conditions	Yield
With hydrogenchloride

: 7200-25-1
Arg

A: 157-06-2
D-arginine

B: 74-79-3
L-arginine

: (R)-5-Guanidino-2-[(1H-indole-3-carbonyl)-amino]-pentanoic acid

A: 771-50-6
1H-indole-3-carboxylic acid

B: 157-06-2
D-arginine

Conditions

Conditions	Yield
With hydrogenchloride at 120℃; for 12h; Product distribution;

DL-arginine: DL-arginine

: 157-06-2
D-arginine

Conditions

Conditions	Yield
With arginase

copper (II)-compound of D-ornithine: copper (II)-compound of D-ornithine

O-methyl-isothiourea: O-methyl-isothiourea

: 157-06-2
D-arginine

Conditions

Conditions	Yield
With sodium hydroxide anschliessend mit H2S;

carbonate dl-arginine: carbonate dl-arginine

A: 157-06-2
D-arginine

B d-ornithine , urea: d-ornithine , urea

Conditions

Conditions	Yield
With water at 37℃; bei der Einwirkung von Leberpresssaft (Arginase) bleibt das l-Arginin bestehen, waehrend das d-Arginin gespalten wird;

: neamphamide A

: 157-06-2
D-arginine

Conditions

Conditions	Yield
With hydrogenchloride In water at 107℃; for 18.5h;

: (-)-leptoclinidamine B trifluoroacetic acid salt

: 157-06-2
D-arginine

Conditions

Conditions	Yield
With hydrogenchloride In water at 100℃; for 8h;

: neamphamide B

A: 24830-94-2
D-allo-threonine

B: 61-90-5
L-leucine

C: 70-47-3
L-asparagine

D: 157-06-2
D-arginine

E: gamma-Glutamylmethylamide

F: 3105-95-1
pipecolinic acid

Conditions

Conditions	Yield
With hydrogenchloride In water at 120℃; for 16h;

...Expand

: neamphamide C

A: 24830-94-2
D-allo-threonine

B: 61-90-5
L-leucine

C: 70-47-3
L-asparagine

D: 157-06-2
D-arginine

E: 6753-62-4
N-methyl-L-glutamic acid

F: 3105-95-1
pipecolinic acid

Conditions

Conditions	Yield
With hydrogenchloride In water at 120℃; for 16h;

...Expand

: neamphamide D

A: 24830-94-2
D-allo-threonine

B: 61-90-5
L-leucine

C: 70-47-3
L-asparagine

D: 157-06-2
D-arginine

E: gamma-Glutamylmethylamide

F: 3105-95-1
pipecolinic acid

Conditions

Conditions	Yield
With hydrogenchloride In water at 120℃; for 16h;

...Expand

: callipeltin N

A: 338-69-2
D-Alanine

B: 632-20-2
D-Threonine

C: 61-90-5
L-leucine

D: 157-06-2
D-arginine

E: 3105-95-1
pipecolinic acid

Conditions

Conditions	Yield
With hydrogenchloride In water at 110℃; for 24h;

...Expand

: callipeltin O

A: 338-69-2
D-Alanine

B: 632-20-2
D-Threonine

C: 61-90-5
L-leucine

D: 157-06-2
D-arginine

E: 3105-95-1
pipecolinic acid

Conditions

Conditions	Yield
With hydrogenchloride In water at 110℃; for 24h;

...Expand

: callipeltin P

A: 338-69-2
D-Alanine

B: 632-20-2
D-Threonine

C: 61-90-5
L-leucine

D: 157-06-2
D-arginine

E: 3105-95-1
pipecolinic acid

Conditions

Conditions	Yield
With hydrogenchloride In water at 110℃; for 24h;

...Expand

: callipeltin Q

A: 338-69-2
D-Alanine

B: 632-20-2
D-Threonine

C: 61-90-5
L-leucine

D: 157-06-2
D-arginine

E: 3105-95-1
pipecolinic acid

Conditions

Conditions	Yield
With hydrogenchloride In water at 110℃; for 24h;

...Expand

: 7200-25-1
Arg

: 56144-54-8
D-3-bromocamphor-10-sulfonic acid ammonium salt

A: 157-06-2
D-arginine

B: L-arginine D-3-bromocamphor-10-sulfonic acid salt

Conditions

Conditions	Yield
In methanol at 20 - 60℃; for 2h;

...Expand

: 7200-25-1
Arg

: 67999-30-8
(1S,3S,4S)-3-bromocamphor-10-sulfonic acid

A: 157-06-2
D-arginine

B: L-arginine D-3-bromocamphor-10-sulfonic acid salt

Conditions

Conditions	Yield
In methanol at 20 - 60℃; for 2h;

...Expand

: 67-56-1
methanol

: 157-06-2
D-arginine

: 22888-59-1, 26340-89-6, 78851-84-0, 111237-99-1, 18598-71-5
methyl (2R)-2-amino-5-carbamimidamidopentanoate dihydrochloride

Conditions

Conditions	Yield
With thionyl chloride	95%
With thionyl chloride Ambient temperature;

: 157-06-2
D-arginine

: 7535-56-0
N-t-butoxycarbonyl-L-phenylalanine 4-nitrophenyl ester

: (tert-butoxycarbonyl)-L-phenylalanyl-D-arginine

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 20℃; for 24h; Condensation;	90%

: 157-06-2
D-arginine

: 154357-42-3
S-(-)-9-fluoro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid

: 627891-14-9
S-(-)-9-fluoro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid D-arginine salt

Conditions

Conditions	Yield
In methanol; water at 60 - 65℃; for 0.25h;	88%
In methanol; water at 60 - 65℃; for 0.25h;	88%

: 12093-10-6
ferrocenecarboxaldehyde

: 157-06-2
D-arginine

: C10H9FeCHNCH(COOH)(CH2)3NHC(NH2)NH

Conditions

Conditions	Yield
With sodium carbonate In ethanol boiling;	87%
With Na2CO3 In ethanol boiling;	87%

: 157-06-2
D-arginine

: 327-97-9, 534-61-2, 906-33-2, 15016-60-1, 15076-00-3, 29587-84-6, 32719-11-2, 72690-58-5, 77209-78-0, 82659-69-6, 82659-70-9, 82659-71-0, 82690-55-9, 93451-45-7, 93451-46-8
chlorogenic acid

: chlorogenic acid D-arginine salt

Conditions

Conditions	Yield
In ethanol; water at 20℃; for 2h;	84.83%

: 157-06-2
D-arginine

: 119072-55-8, 7188-38-7
tert-butylisonitrile

: 1215325-21-5
(2S,4S,5R,6S)-6-isobutyl-2-((2R,3S)-3-isobutylaziridin-2-yl)-3-oxa-1-aza-bicyclo[3.1.0]hexan-4-ol

: 1215324-80-3
(3R,5S,6S,7S)-N-tert-butyl-3-(3-guanidinopropyl)-7-isobutyl-2-oxo-1,4-diazabicyclo[4.1.0]heptane-5-carboxamide

Conditions

Conditions	Yield
In 1,1,1,3',3',3'-hexafluoro-propanol at 20℃; for 1h; optical yield given as %de;	83%

...Expand

: 157-06-2
D-arginine

: 501-53-1
benzyl chloroformate

: 6382-93-0
Nα-Z-D-Arg

Conditions

Conditions	Yield
With sodium hydroxide; sodium hydrogencarbonate	82%

: 5-carboxymethyl-6-azauracil N-succinimidyl ester

: 157-06-2
D-arginine

: N1-[(6-azauracil-5-yl)methylcarbonyl]-D-arginine

Conditions

Conditions	Yield
In 1,4-dioxane; water at 20℃;	80%

: 27167-53-9
N-(benzyloxycarbonyl)-D-alanine N-hydroxysuccinimide ester

: 157-06-2
D-arginine

: Z-D-Ala-D-Arg-OH hydrochloride

Conditions

Conditions	Yield
Stage #1: N-(benzyloxycarbonyl)-D-alanine N-hydroxysuccinimide ester; D-arginine In water; acetonitrile at 20℃; Stage #2: With hydrogenchloride In water; acetonitrile pH=2.5;	73%

: 157-06-2
D-arginine

: 30084-90-3
9H-fluorene-2-carbaldehyde

: C20H24N4O2

Conditions

Conditions	Yield
Stage #1: D-arginine; 9H-fluorene-2-carbaldehyde In methanol for 6h; Reflux; Stage #2: With sodium tetrahydroborate In methanol at 20℃; for 1h;	68%

: 157-06-2
D-arginine

: 66854-58-8
Z(OMe)-Tyr-N3

: 74863-19-7
Z(OMe)-Tyr-D-Arg-OH HCl

Conditions

Conditions	Yield
With triethylamine In water; N,N-dimethyl-formamide at 4℃; for 48h;	62%

: 157-06-2
D-arginine

: 29022-11-5
N-(fluoren-9-ylmethoxycarbonyl)glycine

: 99-05-8
meta-aminobenzoic acid

: 76-05-1
trifluoroacetic acid

: 241146-47-4
6-((S)-1-{[(E)-Allyloxycarbonylimino]-amino-methyl}-3-tert-butoxycarbonylamino-piperidin-2-yloxy)-hexanoic acid

: 3-((R)-2-Amino-5-guanidino-pentanoylamino)-N-[((S)-1-carbamimidoyl-2-hydroxy-piperidin-3-ylcarbamoyl)-methyl]-benzamide; compound with trifluoro-acetic acid

Conditions

Conditions	Yield
With aminomethylated polystyrene resin Solid phase reaction;	48%

...Expand

toluenic phosgene: toluenic phosgene

: 6-chloropurinyl pentanol

: 157-06-2
D-arginine

: N,N-dimethylaminopurinyl pentoxycarbonyl D-arginine

Conditions

Conditions	Yield
With sodium hydrogencarbonate; dimethyl amine In tetrahydrofuran; methanol; water; acetone	43%
With sodium hydrogencarbonate; dimethyl amine In tetrahydrofuran; methanol; water; acetone	43%

...Expand

: 157-06-2
D-arginine

: 696-82-2
2,4,6-trifluoropyrimidine

A: N-(4,6-Difluoro-2-pyrimidyl)-D-arginine

B: N-(2,6-Difluoro-4-pyrimidyl)-D-arginine

Conditions

Conditions	Yield
With sodium carbonate In water at 50℃; for 2h; Yields of byproduct given;	A 40% B n/a
With sodium carbonate In water at 50℃; for 2h; Yield given; Title compound not separated from byproducts;	A 40% B n/a

...Expand

: copper(II) choride dihydrate

: 157-06-2
D-arginine

: pyridine-3,5-dicarboxylate

: Cu(2+)*2NH2C(NH)NHCH2CH2CH2CH(NH2)COOH*C5H3N(COO)2(2-)*5H2O=[Cu(C6H14N4O2)2](C5H3N(COO)2)*5H2O

Conditions

Conditions	Yield
With NaOH In water stoichiometric ratio Cu:L; diffusion of EtOH;	30%

...Expand

: 157-06-2
D-arginine

: 501-53-1
benzyl chloroformate

: tri-carbobenzoxy arginine sodium salt

Conditions

Conditions	Yield
With sodium hydroxide In water at 0℃; for 0.5h;	15%

: 64-17-5
ethanol

: 157-06-2
D-arginine

: 151079-65-1
N,N'-diacetylglycylglycine ethyl ester

: 3757-98-0
Ac-Gly-Gly-OEt

...Expand

: 157-06-2
D-arginine

: 598-72-1
2-Bromopropionic acid

A: 63358-48-5
Nα-((R)-1-carboxy-ethyl)-D-arginine

B: 63358-46-3
Nα-((S)-1-carboxy-ethyl)-D-arginine

Conditions

Conditions	Yield
With water

...Expand

: 157-06-2
D-arginine

: 151079-65-1
N,N'-diacetylglycylglycine ethyl ester

: 3757-98-0
Ac-Gly-Gly-OEt

Conditions

Conditions	Yield
With sodium hydroxide
With ethanol

: 157-06-2
D-arginine

: 70-26-8, 348-66-3, 616-07-9, 7006-33-9
2,5-diaminopentanoic acid

Conditions

Conditions	Yield
bei der Faeulnis;

: 157-06-2
D-arginine

: 2149-70-4
N-nitro-L-arginine

Conditions

Conditions	Yield
With sulfuric acid; nitric acid nitro-d-arginine;

: 157-06-2
D-arginine

A: 70-26-8
L-ornithine

B: 57-13-6
urea

Conditions

Conditions	Yield
bei der Einw. von Leberpresssaft;
With barium dihydroxide
With arginase

: 157-06-2
D-arginine

: 660-88-8
5-aminopentanoic acid

Conditions

Conditions	Yield
bei der Faeulnis;

: 64-17-5
ethanol

: 157-06-2
D-arginine

: 3027-05-2
N,N'-diacetylpiperazin-2,5-dione

: 151079-65-1
N,N'-diacetylglycylglycine ethyl ester

Conditions

Conditions	Yield
at 20℃;

...Expand

: 3397-32-8
N-(benzyloxycarbonyl)-phenylalanine-N-hydroxysuccinimide ester

: 157-06-2
D-arginine

: 88263-48-3
(R)-2-((S)-2-Benzyloxycarbonylamino-3-phenyl-propionylamino)-5-guanidino-pentanoic acid

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 20℃; for 12h;

: 157-06-2
D-arginine

: 114153-81-0
C11H13ClN4O3

: Nα-{[5-(6-hydroxypurin-9-yl)pentoxy]carbonyl}-D-arginine

Conditions

Conditions	Yield
With sodium hydrogencarbonate In tetrahydrofuran Yield given;

: 157-06-2
D-arginine

: C11H13ClN4O2

: Nα-{[5-(purin-9-yl)pentoxy]carbonyl}-D-arginine

Conditions

Conditions	Yield
With sodium hydrogencarbonate In tetrahydrofuran Yield given;

D(-)-Arginine Chemical Properties

Molecular Structure of D-Arginine (CAS NO.157-06-2):

Empirical Formula: C₆H₁₄N₄O₂
Molecular Weight: 174.201
IUPAC Name: 2-amino-5-(diaminomethylideneamino)pentanoic acid
H bond acceptors: 6
H bond donors: 7
Freely Rotating Bonds: 6
Polar Surface Area: 48.38 Å²
Index of Refraction: 1.601
Molar Refractivity: 40.69 cm³
Molar Volume: 118.7 cm³
Surface Tension: 66.1 dyne/cm
Density: 1.46 g/cm³
Flash Point: 201.2 °C
Enthalpy of Vaporization: 72.55 kJ/mol
Boiling Point: 409.1 °C at 760 mmHg
Vapour Pressure: 7.7E-08 mmHg at 25°C
EINECS: 205-866-5
Melting point: 226 °C (dec.)(lit.)
Storage temp.: Store at 0-5
Water Solubility: Soluble
Sensitive: Air Sensitive
Appearance: white to light yellow crystal powder
Product Categories: Amino Acids Derivatives; chiral; Protected amino acid & peptides; Arginine [Arg, R]; Amino Acids and Derivatives; alpha-Amino Acids; Amino Acids; Biochemistry; for Resolution of Acids; Optical Resolution; Synthetic Organic Chemistry; Amino Acids

D(-)-Arginine Safety Profile

The Hazard Codes: Irritant Xi, Harmful Xn
The Risk Statements information of D-Arginine (CAS NO.157-06-2):
36: Irritating to the eyes
20/21/22: Harmful by inhalation, in contact with skin and if swallowed
36/37/38: Irritating to eyes, respiratory system and skin
The Safety Statements information:
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36: Wear suitable protective clothing
WGK Germany: 3
RTECS: CF1934220
F: 9

D(-)-Arginine Specification

D-Arginine , with CAS number of 157-06-2, can be called R-(-)-arginine ; (r)-2-amino-5-guanidinopentanoic acid ; arginine, d- ; h-d-arg-oh ; d-arg ; d-(-)-arginine ; d-arginine . It is a white to light yellow crystal powde. D-Arginine (CAS NO.157-06-2) is used for biochemical research.

Product Name

D(-)-Arginine

Synthetic route

D(-)-Arginine Chemical Properties

D(-)-Arginine Safety Profile

D(-)-Arginine Specification

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