ETHANOLAMINE PHOSPHATE supplier

Name
O-PHOSPHORYLETHANOLAMINE
EINECS
CAS No. 1071-23-4
Article Data34
CAS DataBase
Density 1.554g/cm³
Solubility Soluble in water
Melting Point 241-243 °C(lit.)
Formula C2H8 N O4 P
Boiling Point 335.8°Cat760mmHg
Molecular Weight 141.064
Flash Point 156.9°C
Transport Information
Appearance white powder
Safety Moderately toxic by intravenous route. When heated to decomposition it emits very toxic fumes of PO_x and NO_x.
Risk Codes 25-34
Molecular Structure
Hazard Symbols
Synonyms Ethanol,2-amino-, dihydrogen phosphate (ester) (8CI,9CI); Ethanol, 2-amino-, phosphate(6CI); Phosphoric acid, 2-aminoethyl ester (6CI); 2-Aminoethanol O-phosphate;2-Aminoethyl dihydrogen phosphate; Colamine phosphate; EthanolamineO-phosphate; Mono(2-aminoethyl) phosphate; Monoaminoethyl phosphate; NSC254167; O-Phosphoethanolamine; O-Phosphorylethanolamine; Phosphoethanolamine;Phosphonoethanolamine; Phosphorylethanolamine
PSA 102.59000
LogP -0.24530

Synthetic route

: 141-43-5
ethanolamine

: 1071-23-4
2-aminoethyl dihydrogen phosphate

Conditions

Conditions	Yield
With phosphoric acid at 100℃; under 10 Torr; for 3h;	60%
With phosphoric acid 1) 100 deg C, 10 mmHg, 1 h; 2) 150 deg C, 0.3 mmHg, 3 h;	60%
With phosphoric acid at 185℃; for 8h; Cooling with ice;	45%

: 151-56-4
ethyleneimine

: 1071-23-4
2-aminoethyl dihydrogen phosphate

Conditions

Conditions	Yield
With phosphoric acid at 105℃;

: 497-25-6
dimethylenecyclourethane

: 1071-23-4
2-aminoethyl dihydrogen phosphate

Conditions

Conditions	Yield
With phosphoric acid at 165℃;

: 4167-12-8
2-chloroethyl phosphoric acid

: 1071-23-4
2-aminoethyl dihydrogen phosphate

Conditions

Conditions	Yield
With ammonia; water at 120 - 130℃;

: 14662-76-1
(2-hydroxy-ethyl)-amidophosphoric acid diisopropyl ester

: 1071-23-4
2-aminoethyl dihydrogen phosphate

Conditions

Conditions	Yield
With hydrogenchloride

: 102313-50-8
(2-diphenoxyphosphoryloxy-ethyl)-carbamic acid benzyl ester

: 1071-23-4
2-aminoethyl dihydrogen phosphate

Conditions

Conditions	Yield
With ethanol; palladium Hydrogenation.anschliessend an Platin in Essigsaeure;

: 2002-24-6
2-amino-ethanol hydrochloride

: 1071-23-4
2-aminoethyl dihydrogen phosphate

Conditions

Conditions	Yield
With disodium hydrogenphosphate Gegenwart von alkalischer Phosphatase bei pH 9 und 37grad;

: 1455-05-6
2-chloroethyl phosphorodichloridate

: ammonium hydroxide

: 1071-23-4
2-aminoethyl dihydrogen phosphate

Conditions

Conditions	Yield
at 130℃;

: 65314-76-3
phosphoric acid-(2-amino-ethyl ester)-diphenyl ester

aqueous alkaline solution: aqueous alkaline solution

: 1071-23-4
2-aminoethyl dihydrogen phosphate

: 102313-50-8
(2-diphenoxyphosphoryloxy-ethyl)-carbamic acid benzyl ester

: 64-19-7
acetic acid

platinum /palladium: platinum /palladium

: 1071-23-4
2-aminoethyl dihydrogen phosphate

Conditions

Conditions	Yield
Hydrogenation;

...Expand

: C10H13N2O9P2(3-)

A: 1071-23-4
2-aminoethyl dihydrogen phosphate

B: 54-47-7
pyridoxal 5'-phosphate

Conditions

Conditions	Yield
at 37℃; pH=7.4; Kinetics; Equilibrium constant; aq. phosphate buffer;

: [(2S,3R)-2-amino-3-hydroxyoctadec-4-enyl] dihydrogen phosphate

A: 1071-23-4
2-aminoethyl dihydrogen phosphate

B: 3163-37-9, 51534-41-9, 22644-96-8
(E)-hexadec-2-enal

Conditions

Conditions	Yield
With sphingosine-1-phosphate lyase Enzymatic reaction;

: 26993-30-6
Sphingosine-1-phosphate

A: 1071-23-4
2-aminoethyl dihydrogen phosphate

B: 3163-37-9, 51534-41-9, 22644-96-8
(E)-hexadec-2-enal

Conditions

Conditions	Yield
With pyridoxal 5'-phosphate; human sphingosine-1-phosphate lyase In water; dimethyl sulfoxide at 20℃; for 22h; pH=8; Kinetics; Reagent/catalyst; Enzymatic reaction;

: 1071-23-4
2-aminoethyl dihydrogen phosphate

: 2052-49-5
tetra(n-butyl)ammonium hydroxide

: 2-aminoethyl di-(tetrabutylammonium) phosphonate

Conditions

Conditions	Yield
In water for 4h;	99%

: 1071-23-4
2-aminoethyl dihydrogen phosphate

: 1257405-75-6
azidomethyl 4-nitrophenyl carbonate

: 1257405-79-0
ammonium 2-[(azidomethoxy)carbonylamino]ethylhydrogenphosphate

Conditions

Conditions	Yield
Stage #1: 2-aminoethyl dihydrogen phosphate; azidomethyl 4-nitrophenyl carbonate With water; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 0.5h; Stage #2: With water; ammonium bicarbonate	99%

: 1071-23-4
2-aminoethyl dihydrogen phosphate

: 144-55-8
sodium hydrogencarbonate

: 4055-39-4
mitomycin A

: 18623-11-5
octadecyl silane

: mitomycin C phosphate

Conditions

Conditions	Yield
With triethylamine In methanol; phosphorus pentaoxide; water	97%

...Expand

: 1071-23-4
2-aminoethyl dihydrogen phosphate

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 329223-23-6
(2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}ethoxy)phosphonic acid

Conditions

Conditions	Yield
With sodium carbonate In 1,4-dioxane; water at 20℃; for 1h;	89%
With water; sodium carbonate In N,N-dimethyl-formamide for 0.333333h;	75%

: 75-77-4
chloro-trimethyl-silane

: 1071-23-4
2-aminoethyl dihydrogen phosphate

: 28920-43-6
(fluorenylmethoxy)carbonyl chloride

: 329223-23-6
(2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}ethoxy)phosphonic acid

Conditions

Conditions	Yield
Stage #1: chloro-trimethyl-silane; 2-aminoethyl dihydrogen phosphate In dichloromethane for 2h; Heating; Stage #2: (fluorenylmethoxy)carbonyl chloride With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 6h; Further stages.;	85%

...Expand

: 1071-23-4
2-aminoethyl dihydrogen phosphate

: 24424-99-5
di-tert-butyl dicarbonate

: 932014-80-7
(2-phosphonooxy-ethyl)-carbamic acid tert-butyl ester

Conditions

Conditions	Yield
With sodium carbonate In 1,4-dioxane; water at 20℃; for 17h;	82%

: 1071-23-4
2-aminoethyl dihydrogen phosphate

: zinc(II) oxide

: zinc bis(2-aminoethyl hydrogen phosphate) tetrahydrate

Conditions

Conditions	Yield
In water treated suspension of ZnO in H2O with 2-aminoethyl dihydrogen phosphate; stirring for 10 min at room temp.; filtration; slowly evapn. at 45°C; elem. anal.;	81%

: 1071-23-4
2-aminoethyl dihydrogen phosphate

: 79-04-9
chloroacetyl chloride

: 2-(2-chloroacetamido)ethyl dihydrogen phosphate

Conditions

Conditions	Yield
Stage #1: 2-aminoethyl dihydrogen phosphate With lithium hydroxide In water at 20℃; for 0.5h; pH=Ca.5; Stage #2: chloroacetyl chloride With lithium hydroxide In water pH=Ca.5;	81%
Stage #1: 2-aminoethyl dihydrogen phosphate With lithium hydroxide In water at 20℃; for 0.5h; Stage #2: chloroacetyl chloride In water	81%

: 1071-23-4
2-aminoethyl dihydrogen phosphate

: 54-47-7
pyridoxal 5'-phosphate

: C10H18N2O9P2*H3N

Conditions

Conditions	Yield
Stage #1: 2-aminoethyl dihydrogen phosphate With potassium tert-butylate In methanol at 20℃; for 0.5h; Cooling with ice; Inert atmosphere; Stage #2: pyridoxal 5'-phosphate With potassium tert-butylate In methanol at 0 - 20℃; for 0.5h; Inert atmosphere; Stage #3: With sodium tetrahydroborate In methanol at 0℃; for 4h; Reflux; Darkness; Inert atmosphere;	79%

: 359-06-8
monofluoroacetyl chloride

: 1071-23-4
2-aminoethyl dihydrogen phosphate

: 2-(2-fluoroacetamido)ethyl dihydrogen phosphate

Conditions

Conditions	Yield
Stage #1: 2-aminoethyl dihydrogen phosphate With lithium hydroxide In water at 20℃; for 0.5h; pH=Ca.5; Stage #2: monofluoroacetyl chloride With lithium hydroxide In water pH=Ca.5;	78%
Stage #1: 2-aminoethyl dihydrogen phosphate With lithium hydroxide In water at 20℃; for 0.5h; Stage #2: monofluoroacetyl chloride In water	78%

: 1071-23-4
2-aminoethyl dihydrogen phosphate

: 1077-28-7, 62-46-4
Thioctic acid

: 1085381-76-5
2-(5-(1,2-dithiolan-3-yl)pentanamido)ethyl dihydrogen phosphate

Conditions

Conditions	Yield
Stage #1: Thioctic acid With 1-hydroxy-pyrrolidine-2,5-dione; sodium hydrogencarbonate In water; N,N-dimethyl-formamide pH=7.4; Stage #2: 2-aminoethyl dihydrogen phosphate With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium phosphate In water; N,N-dimethyl-formamide	74%

: 1071-23-4
2-aminoethyl dihydrogen phosphate

: 117-08-8
tetrachlorophthalic anhydride

: 2-(tetrachlorophthalimide)ethane phosphoric acid

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane for 6h; Reflux;	69%

: 1071-23-4
2-aminoethyl dihydrogen phosphate

: 187224-28-8
(5Z,8Z,11Z,14Z)-2,5-dioxopyrrolidin-1-yl icosa-5,8,11,14-tetraenoate

: Anandamide O-phosphate

Conditions

Conditions	Yield
With sodium hydrogencarbonate In tetrahydrofuran Ambient temperature;	60%

: 38020-81-4
2-iodoacetyl chloride

: 1071-23-4
2-aminoethyl dihydrogen phosphate

: 2-(2-iodoacetamido)ethyl dihydrogen phosphate

Conditions

Conditions	Yield
Stage #1: 2-aminoethyl dihydrogen phosphate With lithium hydroxide In water at 20℃; for 0.5h; pH=Ca.5; Stage #2: 2-iodoacetyl chloride With lithium hydroxide In water pH=Ca.5;	58%
Stage #1: 2-aminoethyl dihydrogen phosphate With lithium hydroxide In water at 20℃; for 0.5h; Stage #2: 2-iodoacetyl chloride In water	58%

: 3392-07-2
tert-butyl N-{2-[(2,5-dioxopyrrolidin-1-yl)oxy]-2-oxoethyl}carbamate

: 1071-23-4
2-aminoethyl dihydrogen phosphate

: C9H19N2O7P

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In methanol at 20℃; for 3h;	57%

: 1071-23-4
2-aminoethyl dihydrogen phosphate

: 1425803-45-7
1,3-dioxoisoindolin-2-yl 2-(cyclooct-2-yn-1-yloxy)acetate

: (2-(2-(cyclooct-2-yn-1-yloxy)acetamido)ethyl)phosphonic acid

Conditions

Conditions	Yield
With triethylamine In water; N,N-dimethyl-formamide for 2h;	54%

: 1071-23-4
2-aminoethyl dihydrogen phosphate

: 598-21-0
2-Bromoacetyl bromide

: 52011-43-5
2-(2-bromoacetamido)ethyl dihydrogen phosphate

Conditions

Conditions	Yield
Stage #1: 2-aminoethyl dihydrogen phosphate With lithium hydroxide In water at 20℃; for 0.5h; pH=Ca.5; Stage #2: 2-Bromoacetyl bromide With lithium hydroxide In water pH=Ca.5;	49%
Stage #1: 2-aminoethyl dihydrogen phosphate With lithium hydroxide In water at 20℃; for 0.5h; Stage #2: 2-Bromoacetyl bromide In water	49%

: 1071-23-4
2-aminoethyl dihydrogen phosphate

: 501-53-1
benzyl chloroformate

: 119220-16-5
dilithium 2-(benzyloxycarbonylamino)ethyl phosphate

Conditions

Conditions	Yield
With lithium hydroxide In benzene for 2h;	47%

: chlorine e6 anhydride

: 111-86-4
n-Octylamine

: 1071-23-4
2-aminoethyl dihydrogen phosphate

: C36H42N5O9P*C8H19N

Conditions

Conditions	Yield
Stage #1: 2-aminoethyl dihydrogen phosphate With sodium hydrogencarbonate In dimethyl sulfoxide at 20℃; for 0.5h; Stage #2: chlorine e6 anhydride In dichloromethane; dimethyl sulfoxide at 20℃; Darkness; Stage #3: n-Octylamine In dichloromethane at 20℃; for 0.5h;	44%

...Expand

: 1071-23-4
2-aminoethyl dihydrogen phosphate

: 103-80-0
phenylacetyl chloride

: 2-(2-phenylacetamido)ethyl dihydrogen phosphate

Conditions

Conditions	Yield
Stage #1: 2-aminoethyl dihydrogen phosphate With lithium hydroxide In water at 20℃; for 0.5h; pH=Ca.5; Stage #2: phenylacetyl chloride With lithium hydroxide In water pH=Ca.5;	32%
Stage #1: 2-aminoethyl dihydrogen phosphate With lithium hydroxide In water at 20℃; for 0.5h; Stage #2: phenylacetyl chloride In water	32%

: mono(6-bromo-6-deoxy)-β-cyclodextrin

: 1071-23-4
2-aminoethyl dihydrogen phosphate

: 121-44-8
triethylamine

: C6H15N*C46H82N2O41P2

Conditions

Conditions	Yield
In water; N,N-dimethyl-formamide at 80℃; under 7600.51 Torr; for 168h; Inert atmosphere; Autoclave;	30%

...Expand

: 299969-20-3
2,5-dioxopyrrolidin-1-yl biphenyl-4-carboxylate

: 1071-23-4
2-aminoethyl dihydrogen phosphate

: 1191406-80-0
N-(4-phenylbenzoyl)-2-aminoethyl phosphate

Conditions

Conditions	Yield
With 1-methyl-1H-imidazole; triethylamine In water; N,N-dimethyl-formamide at 20℃; for 3h;	23%

: 1071-23-4
2-aminoethyl dihydrogen phosphate

: 1191406-77-5
4-(N-benzylamino)benzoic acid N-hydroxysuccinimide ester

: 1191406-78-6
N-(4-(N-benzylamino)benzoyl)-2-aminoethyl phosphate

Conditions

Conditions	Yield
With 1-methyl-1H-imidazole; triethylamine In water; N,N-dimethyl-formamide at 20℃; for 3h;	23%

: 1071-23-4
2-aminoethyl dihydrogen phosphate

: C30H47NO6

: (2-((4R)-4-((3R,5S,6R,7R,10S,13R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthrene-17-yl)pentanoylamino)ethyl)phosphonic acid

Conditions

Conditions	Yield
With sodium carbonate In water; N,N-dimethyl-formamide at 20℃; for 24h;	22%

: 1071-23-4
2-aminoethyl dihydrogen phosphate

: 2946-39-6
8-bromoadenosine

: 1151916-63-0
3-[6-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyltetrahydrofuran-2-yl)-9H-purin-8-ylamino]-propionic acid

Conditions

Conditions	Yield
With potassium carbonate In water for 24h; Inert atmosphere; Reflux;	14%

ETHANOLAMINE PHOSPHATE Chemical Properties

Ethanolamine phosphate(1071-23-4)'s molecular formula is C₂H₈NO₄P and its formula weight is 141.06.
Ethanolamine phosphate(1071-23-4) has a melting point of 241-243 °C(lit.).
Ethanolamine phosphate(1071-23-4) has the property of being dissolved in water. It is slightly soluble in methanol and ethanol.
The molecular structure of ethanolamine phosphate(1071-23-4):

ETHANOLAMINE PHOSPHATE Uses

Ethanolamine phosphate(1071-23-4) is used in biochemical research and fat metabolism research.

ETHANOLAMINE PHOSPHATE Toxicity Data With Reference

ivn-mus LD50:639 mg/kg

RPOBAR Research Progress in Organic Biological and Medicinal Chemistry. 2 (1970),316.

ETHANOLAMINE PHOSPHATE Consensus Reports

Reported in EPA TSCA Inventory.

ETHANOLAMINE PHOSPHATE Safety Profile

Moderately toxic by intravenous route. When heated to decomposition it emits very toxic fumes of PO_x and NO_x.

ETHANOLAMINE PHOSPHATE Specification

Handling: Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood.
Storage: Keep refrigerated. (Store below 4°C/39°F.) Store in a tightly closed container. Store in a dry area. Corrosives area.

Product Name

O-PHOSPHORYLETHANOLAMINE

Synthetic route

ETHANOLAMINE PHOSPHATE Chemical Properties

ETHANOLAMINE PHOSPHATE Uses

ETHANOLAMINE PHOSPHATE Toxicity Data With Reference

ETHANOLAMINE PHOSPHATE Consensus Reports

ETHANOLAMINE PHOSPHATE Safety Profile

ETHANOLAMINE PHOSPHATE Specification

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