Methyl carbamate supplier | CasNO.598-55-0

Name
Methyl carbamate
EINECS 209-939-2
CAS No. 598-55-0
Article Data88
CAS DataBase
Density 1.092 g/cm³
Solubility 700 g/L (20 °C) in water
Melting Point 56-58 °C(lit.)
Formula C₂H₅NO₂
Boiling Point 178.7 °C at 760 mmHg
Molecular Weight 75.0672
Flash Point 105.2 °C
Transport Information
Appearance white adhering crystals
Safety 26-36/37-22
Risk Codes 36-40
Molecular Structure
Hazard Symbols Xn
Synonyms Methylurethane;NSC 3054;Urethylane;
PSA 52.32000
LogP 0.41180

Synthetic route

: 67-56-1
methanol

: 57-13-6
urea

: 598-55-0
methyl carbamate

Conditions

Conditions	Yield
With alumina supported titanium dioxide-bismuth oxide metal oxide catalyst at 120℃; for 8h; Sealed tube;	99.41%
Stage #1: methanol; urea at 30℃; for 20h; Autoclave; Stage #2: With carbon dioxide; 6O4P(3-)5Ni(2+)5Ca(2+)*2F(1-) at 160℃; under 4500.45 Torr; for 6h; Temperature; Concentration;	98.9%
With silica supported titanium dioxide at 160℃; under 17251.7 Torr; for 8h; Temperature; Pressure; Inert atmosphere;	98%

: 57-13-6
urea

: 616-38-6
carbonic acid dimethyl ester

: 598-55-0
methyl carbamate

Conditions

Conditions	Yield
With Na-ZnO-ZrO2 / γ-Al2O3 at 180℃; for 6h; Temperature; Reagent/catalyst; Autoclave;	98.8%

: 80284-00-0
C9H10N2O6S

A: 598-55-0
methyl carbamate

B: ammonium salt of N-nitro-p-toluenesulfamide

Conditions

Conditions	Yield
With ammonia In diethyl ether for 0.0833333h;	A 78% B 92%

: 67-56-1
methanol

: 70678-13-6
1,2-bis(1-isocyanato-1-methylethyl)diazene

A: 112700-85-3
5,5-dimethyl-Δ1-1,2,4-triazolin-3-one

B: 598-55-0
methyl carbamate

C: 2-methoxy-2-methoxycarbonylaminopropane

D: [1-(1-Methoxycarbonylamino-1-methyl-ethylazo)-1-methyl-ethyl]-carbamic acid methyl ester

Conditions

Conditions	Yield
for 2h; Product distribution; Mechanism; Heating; other alcohols; var. reaction time; var. temperatures;	A 90% B n/a C n/a D n/a
for 2h; Heating; Yield given. Yields of byproduct given;

...Expand

: 671-50-1
methyl aziridine-1-carboxylate

A: 151-56-4
ethyleneimine

B: 598-55-0
methyl carbamate

Conditions

Conditions	Yield
With ammonia In ethanol at 18 - 25℃; for 24h;	A n/a B 90%

: 67-56-1
methanol

: 57-13-6
urea

A: 598-55-0
methyl carbamate

B: 616-38-6
carbonic acid dimethyl ester

Conditions

Conditions	Yield
at 179.84℃; for 10h;	A 84.8% B 6.5%
With zinc/aluminum mixed oxide at 179.84℃; for 10h; Reagent/catalyst; Autoclave;	A 55.1% B 36.5%
calcined La(NO3)3x6H2O at 170℃; under 14821 Torr; for 4h; Product distribution / selectivity; Autoclave; Inert atmosphere;	A 41.2% B 53.4%
With Zn/Ca-catalyst at 179.84℃; for 10h;	A 50.5% B 41.2%
With Ga2O3/CeO2-Al2O3 at 110℃; for 5h;

...Expand

: 67-56-1
methanol

: 590-28-3
potassium cyanate

: 598-55-0
methyl carbamate

Conditions

Conditions	Yield
With para-dodecylbenzenesulfonic acid In neat (no solvent) at 60℃; for 0.5h; Green chemistry;	80%
With DBSA at 60℃; for 1h;

: 79-22-1
methyl chloroformate

: 598-55-0
methyl carbamate

Conditions

Conditions	Yield
With triethylamine In methanol; dichloromethane; ethyl acetate	78%
With ammonia; benzene
With potassium hydrogencarbonate In water

: 67-56-1
methanol

: 2911-21-9
2,4-dioxo-6-methyl-3,4-dihydro-2H-1,3-oxazine

A: 105-45-3
acetoacetic acid methyl ester

B: 598-55-0
methyl carbamate

Conditions

Conditions	Yield
With triethylamine for 24h; Heating;	A 70% B 15%

...Expand

: 4651-91-6
3-cyano-2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene

: 79-22-1
methyl chloroformate

: 598-55-0
methyl carbamate

Conditions

Conditions	Yield
With sodium hydrogencarbonate In butanone	66%

: 67-56-1
methanol

: 57-13-6
urea

A: 6642-30-4
methyl N-methylcarbamate

B: 598-55-0
methyl carbamate

C: 616-38-6
carbonic acid dimethyl ester

Conditions

Conditions	Yield
With ZnO-SrO at 170℃; for 6h; Reagent/catalyst; Temperature; Time;	A 17% B 55% C 28%
With MgZn1.7Al hydrotalcite calcined at 450°C at 200℃; under 15001.5 Torr; for 4h; Catalytic behavior; Time; Autoclave;	A 14% B 28% C 28%

...Expand

: 82317-28-0, 82317-30-4
(2E)-2,3-Diisopropyl-azimin-1-carbonsaeure-methylester

A: 27593-52-8
N-(1-Aethoxyaethyl)carbaminsaeure-methylester

B: 598-55-0
methyl carbamate

C: trans-2,3-Diisopropyl-triaziridin-1-carbonsaeure-methylester

D: cis-2,3-Diisopropyl-triaziridin-1-carbonsaeure-methylester

Conditions

Conditions	Yield
In diethyl ether at 12℃; Irradiation; Yield given. Further byproducts given. Yields of byproduct given. Title compound not separated from byproducts;	A 7% B n/a C 31% D n/a
In diethyl ether at 12℃; Irradiation; Yield given. Further byproducts given. Title compound not separated from byproducts;	A 5% B n/a C 18% D n/a
In diethyl ether at 12℃; Irradiation; Further byproducts given;	A 5% B n/a C 18% D n/a
In diethyl ether at 12℃; Irradiation; Further byproducts given. Yields of byproduct given;	A 5% B n/a C 18% D n/a
In diethyl ether at 12℃; Irradiation; Yield given. Further byproducts given;	A 5% B n/a C 18% D n/a

...Expand

: 82317-28-0, 82317-30-4
(2E)-2,3-Diisopropyl-azimin-1-carbonsaeure-methylester

A: 598-55-0
methyl carbamate

B: 2-Isopropyl-3-isopropyliden-triazan-1-carbonsaeure-methylester

C: trans-2,3-Diisopropyl-triaziridin-1-carbonsaeure-methylester

D: cis-2,3-Diisopropyl-triaziridin-1-carbonsaeure-methylester

Conditions

Conditions	Yield
In diethyl ether at 12℃; Irradiation; Yield given. Further byproducts given;	A n/a B n/a C 18% D n/a

...Expand

: 67-56-1
methanol

: 60-29-7
diethyl ether

: 420-05-3
cyanic acid

A: 761-89-7
allophanic acid methyl ester

B: 598-55-0
methyl carbamate

...Expand

: 67-56-1
methanol

: 420-05-3
cyanic acid

A: 761-89-7
allophanic acid methyl ester

B: 598-55-0
methyl carbamate

...Expand

: 67-56-1
methanol

: 463-72-9
carbamic chloride

: 598-55-0
methyl carbamate

: 67-56-1
methanol

: 3315-16-0
silver cyanate

: 598-55-0
methyl carbamate

Conditions

Conditions	Yield
With hydrogen sulfide
With hydrogenchloride

: 101970-86-9
methyl 1,1,1-trichloromethyl carbonate

A: 57-13-6
urea

B: 598-55-0
methyl carbamate

Conditions

Conditions	Yield
With chloroform; ammonia

: 2216-51-5
(-)-menthol

: 4737-20-6
cinnamoyl isocyanate

: 598-55-0
methyl carbamate

Conditions

Conditions	Yield
at 130℃;

: 4525-33-1
dimethyl dicarbonate

: 598-55-0
methyl carbamate

Conditions

Conditions	Yield
With ethanol; ammonia

: 67-56-1
methanol

: 506-77-4
cyanogen chloride

: 598-55-0
methyl carbamate

: 67-56-1
methanol

: 17197-62-5
3,3-diisopropyl-azetidine-2,4-dione

: 598-55-0
methyl carbamate

Conditions

Conditions	Yield
Irradiation;

: 67-56-1
methanol

: 13730-13-7
silyl isocyanate

: 598-55-0
methyl carbamate

: 1683-76-7
3,3,3-Trifluor-2-chlor-2-nitro-propionsaeure-methylester

: 598-55-0
methyl carbamate

Conditions

Conditions	Yield
(i) NH3, Et2O, (ii) (heating); Multistep reaction;

: 70678-13-6
1,2-bis(1-isocyanato-1-methylethyl)diazene

A: 112700-85-3
5,5-dimethyl-Δ1-1,2,4-triazolin-3-one

B: 598-55-0
methyl carbamate

C: 2-methoxy-2-methoxycarbonylaminopropane

D: [1-(1-Methoxycarbonylamino-1-methyl-ethylazo)-1-methyl-ethyl]-carbamic acid methyl ester

Conditions

Conditions	Yield
With methanol for 2h; Heating; Yield given;

...Expand

: 52200-01-8
phenoxysulfonyl-carbamic acid methyl ester

A: 67-56-1
methanol

B: 598-55-0
methyl carbamate

C: 108-95-2
phenol

Conditions

Conditions	Yield
With hydrogen chloride In [D3]acetonitrile at 50℃; Rate constant; Thermodynamic data; other solvent; var. temp. and pH's; ΔH(excit.); ΔS(excit.); deuterium isotope effect;

...Expand

: 52200-06-3
(4-chloro-phenoxysulfonyl)-carbamic acid methyl ester

A: 67-56-1
methanol

B: 106-48-9
4-chloro-phenol

C: 598-55-0
methyl carbamate

Conditions

Conditions	Yield
With hydrogen chloride In [D3]acetonitrile at 50℃; Rate constant; Thermodynamic data; other solvent; var. temp. and pH's; ΔH(excit.); ΔS(excit.); deuterium isotope effect;

...Expand

: 92385-24-5
(4-nitro-phenoxysulfonyl)-carbamic acid methyl ester

A: 67-56-1
methanol

B: 100-02-7
4-nitro-phenol

C: 598-55-0
methyl carbamate

Conditions

Conditions	Yield
With hydrogen chloride In [D3]acetonitrile at 50℃; Rate constant; Thermodynamic data; other solvent; var. temp. and pH's; ΔH(excit.); ΔS(excit.); deuterium isotope effect;

...Expand

: 598-55-0
methyl carbamate

: 5659-91-6
methyl N-(sulfinylidene)carbamate

Conditions

Conditions	Yield
Stage #1: methyl carbamate With thionyl chloride In diethyl ether at 0 - 20℃; for 0.583333h; Inert atmosphere; Stage #2: With pyridine In diethyl ether at 20℃; for 3h; Inert atmosphere;	100%
With pyridine; thionyl chloride In diethyl ether at 0 - 25℃; for 3h;	76%
With pyridine; thionyl chloride
With pyridine; thionyl chloride In diethyl ether at 0℃; for 3.5h; Inert atmosphere;

: 1022972-70-8
3-amino-5,5-dimethyl-8-nitro-4,5-dihydro-1H-benzo[b]azepin-2(3H)-one

: 598-55-0
methyl carbamate

: 1022945-76-1
(5,5-dimethyl-8-nitro-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-3-yl)carbamic acid methyl ester

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In dichloromethane for 0.0833333h;	100%

: 598-55-0
methyl carbamate

: 21563-73-5
2-aminobenzoyl chloride

: 607-68-1
2,4-dichloroquinazoline

Conditions

Conditions	Yield
With pyridine; tetrachloromethane; titanium(IV) oxide; vanadia; tungsten(VI) oxide; tin(IV) oxide In N,N-dimethyl-formamide at 120 - 230℃; under 2250.23 - 6000.6 Torr; for 32h; Solvent; Temperature; Pressure; Reagent/catalyst;	99.1%

: 62668-02-4
(E)-1,3-diphenyl-2-propen-1-ol

: 598-55-0
methyl carbamate

: 33143-50-9
(E)-N-(1,3-diphenylallyl) methyl carbamate

Conditions

Conditions	Yield
With potassium hexafluorophosphate; bismuth(lll) trifluoromethanesulfonate; calcium sulfate In 1,4-dioxane at 23 - 26℃; for 0.2h;	99%
With aluminium(III) triflate In nitromethane at 20℃; for 0.166667h;	94%

: iso-propyl 2-(2-nitrophenyl)-4-oxobutanoate

: 598-55-0
methyl carbamate

: isopropyl 4-(methoxycarbonylamino)-2-(2-nitrophenyl)butanoate

Conditions

Conditions	Yield
With triethylsilane; trifluoroacetic acid In acetonitrile at 70℃; for 24h; Inert atmosphere;	99%

: 101-02-0
triphenyl phosphite

: 24964-64-5
3-Cyanobenzaldehyde

: 598-55-0
methyl carbamate

: methyl ((3-cyanophenyl)(diphenoxyphosphoryl)methyl)carbamate

Conditions

Conditions	Yield
With copper(II) bis(trifluoromethanesulfonate) In dichloromethane at 20℃; for 16h; Oleksyszyn Synthesis;	99%

...Expand

: 4-methyl-N-(2-(1-methyl-1H-indol-3-yl)ethyl)-N-(phenylethynyl)benzenesulfonamide

: 598-55-0
methyl carbamate

: methyl 1-methyl-5′-phenyl-1′-tosyl-2′,3′-dihydro-1′H-spiro[indoline-3,4′-pyridine]-2-yl carbamate

Conditions

Conditions	Yield
With silver trifluoromethanesulfonate; triphenylphosphine In toluene at 20℃; for 5h; Inert atmosphere; diastereoselective reaction;	99%

: 13987-61-6
N-methylene-tert-butylamine

: 598-55-0
methyl carbamate

: 130157-99-2
{[tert-Butyl-(methoxycarbonylamino-methyl)-amino]-methyl}-carbamic acid methyl ester

Conditions

Conditions	Yield
for 3h; Heating;	98%

: 598-55-0
methyl carbamate

: 298-12-4
Glyoxilic acid

: 56674-26-1
Hydroxy-methoxycarbonylamino-acetic acid

Conditions

Conditions	Yield
In diethyl ether	98%
In diethyl ether	98%
With water In diethyl ether	98%

: 100-52-7
benzaldehyde

: 598-55-0
methyl carbamate

: 135-19-3
β-naphthol

: methyl N-(2-hydroxynaphthalen-1-yl)(phenyl)methyl carbamate

Conditions

Conditions	Yield
With nano-silica-bonded 3-(n-propyl)-1-sulfoimidazolium chloride In neat (no solvent) at 70℃; for 0.216667h;	98%
With saccharin sulfonic acid In neat (no solvent) at 70℃; for 0.166667h; Green chemistry;	97%
With 4-methyl-4-sulfonic acid morpholinium chloride In neat (no solvent) at 100℃; for 0.05h; Reagent/catalyst;	97%

...Expand

: 104-88-1
4-chlorobenzaldehyde

: 598-55-0
methyl carbamate

: 135-19-3
β-naphthol

: methyl N-(4-chlorophenyl)(2-hydroxynaphthalen-1-yl)methyl carbamate

Conditions

Conditions	Yield
With 4-methyl-4-sulfonic acid morpholinium chloride In neat (no solvent) at 100℃; for 0.0333333h; Catalytic behavior; Concentration; Solvent; Temperature;	98%
With nano-silica-bonded 3-(n-propyl)-1-sulfoimidazolium chloride In neat (no solvent) at 70℃; for 0.216667h;	97%
With graphene oxide supported imidazolium based dicationic ionic liquid at 80℃; for 0.0833333h;	97%

...Expand

: 99-61-6
3-nitro-benzaldehyde

: 598-55-0
methyl carbamate

: 135-19-3
β-naphthol

: 1071838-57-7
methyl ((2-hydroxynaphthalen-1-yl)(3-nitrophenyl)methyl)carbamate

Conditions

Conditions	Yield
With nano-silica-bonded 3-(n-propyl)-1-sulfoimidazolium chloride In neat (no solvent) at 70℃; for 0.133333h;	98%
With trityl chloride In neat (no solvent) at 70℃; for 0.116667h;	97%
With a magnetite (Fe3O4 )supported -SO3H functionalized benzimidazolium based ionic liquid In neat (no solvent) at 80℃; for 0.0666667h; Green chemistry;	97%

...Expand

: 555-16-8
4-nitrobenzaldehdye

: 598-55-0
methyl carbamate

: 135-19-3
β-naphthol

: 1071838-54-4
methyl N-(2-hydroxynaphthalen-1-yl)(4-nitrophenyl)methyl carbamate

Conditions

Conditions	Yield
With trityl chloride In neat (no solvent) at 70℃; for 0.133333h;	98%
With nano-silica-bonded 3-(n-propyl)-1-sulfoimidazolium chloride In neat (no solvent) at 70℃; for 0.15h;	98%
With saccharin sulfonic acid In neat (no solvent) at 70℃; for 0.166667h; Green chemistry;	97%

...Expand

: 587-04-2
3-Chlorobenzaldehyde

: 598-55-0
methyl carbamate

: 135-19-3
β-naphthol

: 1071838-56-6
methyl ((3-chlorophenyl)(2-hydroxynaphthalen-1-yl)methyl)carbamate

Conditions

Conditions	Yield
With trityl chloride In neat (no solvent) at 70℃; for 0.0666667h;	98%
With nano-silica-bonded 3-(n-propyl)-1-sulfoimidazolium chloride In neat (no solvent) at 70℃; for 0.2h;	97%
With N,N,N-triethyl-N-sulfoethanammonium chloride at 110℃; for 0.166667h;	94%

...Expand

: 934-72-5
Methyl p-tolyl sulfoxide

: 598-55-0
methyl carbamate

: methyl[methyl(4-methylphenyl)oxido-λ6-sulfanylidene]carbamate

Conditions

Conditions	Yield
With dirhodium tetraacetate; [bis(acetoxy)iodo]benzene; magnesium oxide In dichloromethane at 20 - 40℃; for 8h;	98%
With dirhodium tetraacetate; [bis(acetoxy)iodo]benzene; magnesium oxide In dichloromethane at 40℃; for 8h;	98%

: 122-97-4
3-Phenyl-1-propanol

: 598-55-0
methyl carbamate

: 673-31-4
phenprobamate

Conditions

Conditions	Yield
With di-n-butyltin maleate In toluene for 3h; Reflux;	98%

: 822-67-3
Cyclohex-2-enol

: 598-55-0
methyl carbamate

: 119449-77-3
cyclohex-2-enyl carbamate

Conditions

Conditions	Yield
With di-n-butyltin maleate In toluene for 3h; Reflux;	98%

: 3132-99-8
m-bromobenzoic aldehyde

: 598-55-0
methyl carbamate

: 135-19-3
β-naphthol

: C19H16BrNO3

Conditions

Conditions	Yield
With 4-methyl-4-sulfonic acid morpholinium chloride In neat (no solvent) at 100℃; for 0.05h; Reagent/catalyst;	97%
With 1-methyl-3-(4-sulfobutyl)-1H-imidazol-3-ium hydrogensulfate at 90℃; for 2h; Neat (no solvent);	90%
With magnesium hydrogen sulfate In neat (no solvent) at 100℃; for 0.383333h; Green chemistry;	90%
With 1-n-butyl-3-methylimidazolim bromide; toluene-4-sulfonic acid at 60℃; for 1h;	75%

...Expand

: 112-53-8
1-dodecyl alcohol

: 598-55-0
methyl carbamate

: 6320-52-1
dodecyl carbamate

Conditions

Conditions	Yield
With di-n-butyltin maleate In toluene for 3h; Reflux;	97%

: 818-08-6
di(n-butyl)tin oxide

: 598-55-0
methyl carbamate

: 1,1,3,3-tetrabutyl-1-methoxy-3-isocyanatodistannoxane

Conditions

Conditions	Yield
In methanol High Pressure; heating at 393-433 K in autoclave; MeOH was distilled off at 343-353 K, drying in vacuo at 333-343 K; elem.anal.;	96.9%

: 67-56-1
methanol

: 124-09-4
1,6-Hexanediamine

: 598-55-0
methyl carbamate

: 6030-54-2
1,6-bis(methoxycarbonylamino)hexane

Conditions

Conditions	Yield
With 5.1 wt% Ni/Fe3O4 at 190℃; under 11251.1 - 16501.7 Torr; for 5h; Autoclave; Inert atmosphere;	96%
With cerium(IV) oxide at 150 - 210℃; for 6h; Reagent/catalyst; Temperature; Inert atmosphere;	96.9%

...Expand

: 1165952-91-9
cyclohexa-1,3-diene

: 598-55-0
methyl carbamate

: 86766-64-5
N-(cyclohex-2-enyl) methyl carbamate

Conditions

Conditions	Yield
With bismuth(lll) trifluoromethanesulfonate; tetrakis(actonitrile)copper(I) hexafluorophosphate; 1,2-bis-(diphenylphosphino)ethane In 1,4-dioxane at 50℃; for 18h;	96%

: 1122-91-4
4-bromo-benzaldehyde

: 598-55-0
methyl carbamate

: 135-19-3
β-naphthol

: methyl N-(4-bromophenyl)(2-hydroxynaphthalen-1-yl)methyl carbamate

Conditions

Conditions	Yield
With N,N,N-triethyl-N-sulfoethanammonium chloride at 110℃; for 0.166667h;	96%
With trityl chloride In neat (no solvent) at 70℃; for 0.133333h;	95%
With saccharin sulfonic acid In neat (no solvent) at 70℃; for 0.0833333h; Green chemistry;	95%

...Expand

: 67-56-1
methanol

: 124-22-1
n-Dodecylamine

: 598-55-0
methyl carbamate

: 66769-57-1
methyl n-dodecylcarbamate

Conditions

Conditions	Yield
With 5.1 wt% Ni/Fe3O4 at 190℃; under 11251.1 - 16501.7 Torr; for 5h; Autoclave; Inert atmosphere;	96%

...Expand

: 98-85-1, 13323-81-4
1-Phenylethanol

: 598-55-0
methyl carbamate

: 76926-67-5
methyl (1-phenylethyl)carbamate

Conditions

Conditions	Yield
With aluminium(III) triflate In nitromethane at 50℃; for 0.166667h; Microwave irradiation;	96%

: 1-(4-methylbenzensulfonyl)-4-(thien-3-yl)-1H-1,2,3-triazole

: 598-55-0
methyl carbamate

: 1514928-15-4
(Z)-methyl (2-(4-methylphenylsulfonamido)-1-(thiophen-3-yl)vinyl)carbamate

Conditions

Conditions	Yield
With rhodium(II) octanoate dimer In chloroform at 75℃; Inert atmosphere; Glovebox; Microwave irradiation; stereoselective reaction;	96%

: 1078739-24-8
4-(4-methoxyphenyl)-1-tosyl-1H-1,2,3-triazole

: 598-55-0
methyl carbamate

: 1514928-17-6
(Z)-methyl (1-(4-methoxyphenyl)-2-(4-methylphenylsulfonamido)vinyl)carbamate

Conditions

Conditions	Yield
With rhodium(II) octanoate dimer In chloroform at 75℃; Inert atmosphere; Glovebox; Microwave irradiation; stereoselective reaction;	96%

: 70286-36-1
p-methylbenzaldoxime methyl ether

: 598-55-0
methyl carbamate

: [2-(methoxyimino-methyl)-5-methyl-phenyl]-carbamic acid methyl ester

Conditions

Conditions	Yield
Stage #1: p-methylbenzaldoxime methyl ether; palladium diacetate In 1,2-dichloro-ethane at 80℃; for 1h; Stage #2: methyl carbamate With dipotassium peroxodisulfate In 1,2-dichloro-ethane at 80℃;	95%

Methyl carbamate Specification

The Methyl carbamate, with the CAS registry number 598-55-0 and EINECS registry number 209-939-2, is also known as Methoxyformamide. And the molecular formula of this chemical is C₂H₅NO₂. It is a carbamate ester with th apperance of white adhering crystals. What's more, it is used by the textile industry to manufacture resins to be applied on polyester/cotton blend fabrics as durable-press finishes. And it is also used as intermediate in the pharmaceuticals and Pesticide industry. In addition, it is used as selective solvent for dutrex.

The physical properties of Methyl carbamate are as following: (1)ACD/LogP: -0.68; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -0.68; (4)ACD/LogD (pH 7.4): -0.68; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 10.15; (8)ACD/KOC (pH 7.4): 10.15; (9)#H bond acceptors: 3; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 1; (12)Polar Surface Area: 29.54 Å²; (13)Index of Refraction: 1.399; (14)Molar Refractivity: 16.62 cm³; (15)Molar Volume: 68.7 cm³; (16)Polarizability: 6.59×10^-24cm³; (17)Surface Tension: 33.6 dyne/cm; (18)Density: 1.092 g/cm³; (19)Flash Point: 105.2 °C; (20)Enthalpy of Vaporization: 41.5 kJ/mol; (21)Boiling Point: 178.7 °C at 760 mmHg; (22)Vapour Pressure: 0.976 mmHg at 25°C.

Preparation of Methyl carbamate: Heat methyl alcohol to boil, and add urea with stirring. Reflux for 30 hours, and leach for 2 times with boiling sherwood oil. Collect the 175-177 °C distillates after fractionation, and the distillates are the desired product. The yield is about 75%.
1. ClCOOCH₃ + 2NH₃ → NH₂COOCH₃2. NH₂CONH₂ + CH₃OH → NH₂COOCH₃ + NH₃

You should be cautious while dealing with this chemical. It irritates eyes, and there's limited evidence of a carcinogenic effect about this chemical. Therefore, you had better take the following instructions: Do not breathe dust; Wear suitable protective clothing and gloves, and in case of contacting with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C(OC)N
(2)InChI: InChI=1/C2H5NO2/c1-5-2(3)4/h1H3,(H2,3,4)
(3)InChIKey: GTCAXTIRRLKXRU-UHFFFAOYAJ

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	oral	6200mg/kg (6200mg/kg)		National Toxicology Program Technical Report Series. Vol. NTP-TR-328, Pg. 1987,
mouse	LD50	subcutaneous	4450mg/kg (4450mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Australian Journal of Experimental Biology and Medical Science. Vol. 45, Pg. 507, 1967.
mouse	LDLo	intraperitoneal	200mg/kg (200mg/kg)		Toxicology and Applied Pharmacology. Vol. 23, Pg. 288, 1972.
quail	LD50	oral	21mg/kg (21mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Ecotoxicology and Environmental Safety. Vol. 8, Pg. 551, 1984.
rabbit	LD50	skin	> 2gm/kg (2000mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)	Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 1, Pg. 161, 1992.
rat	LD50	oral	2500mg/kg (2500mg/kg)		National Toxicology Program Technical Report Series. Vol. NTP-TR-328, Pg. 1987,

Product Name

Methyl carbamate

Synthetic route

Methyl carbamate Specification

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