Methylthioethane supplier | CasNO.624-89-5

Name
Methylthioethane
EINECS 210-868-4
CAS No. 624-89-5
Article Data41
CAS DataBase
Density 0.827g/cm³
Solubility Miscible with alcohols and oils. Immiscible with water.
Melting Point -106 °C(lit.)
Formula C₃H₈S
Boiling Point 63.2 °C at 760 mmHg
Molecular Weight 76.1625
Flash Point 5 °F
Transport Information
Appearance Colorless liquid.
Safety 16-23-24/25
Risk Codes 11
Molecular Structure
Hazard Symbols F
Synonyms Sulfide,ethyl methyl (6CI,8CI);(Methylthio)ethane;1-(Methylthio)ethane;2-Thiabutane;Ethyl methyl sulfide;Ethyl methyl thioether;Methyl ethyl sulfide;
PSA 25.30000
LogP 1.36930

Synthetic route

: 617-86-7
triethylsilane

: 4396-19-4
bis(ethylthio)methane

A: 624-89-5
Ethyl methyl sulfide

B: 18236-32-3
triethyl(ethylthio)silane

Conditions

Conditions	Yield
With nickel at 120℃; for 1h; Product distribution;	A 95% B 97%
nickel at 120℃; for 1h;	A 95% B 97%

...Expand

: 74-93-1
methylthiol

: 74-85-1
ethene

A: 75-18-3
dimethylsulfide

B: 624-89-5
Ethyl methyl sulfide

C: 352-93-2
diethyl sulphide

D: 75-08-1
ethanethiol

Conditions

Conditions	Yield
With 2,2-dimethoxy-2-phenylacetophenone at 45℃; under 2250.23 - 6750.68 Torr; for 14.1h; UV-irradiation;	A n/a B 97% C n/a D n/a

...Expand

: 617-86-7
triethylsilane

: 6267-24-9
tris(ethylsulfanyl)methane

A: 624-89-5
Ethyl methyl sulfide

B: 4396-19-4
bis(ethylthio)methane

C: 18236-32-3
triethyl(ethylthio)silane

Conditions

Conditions	Yield
With zinc(II) iodide at 100℃; for 3.5h; Product distribution; oth. reagent;	A 90% B 15% C 94%

...Expand

: 75-08-1
ethanethiol

: 74-88-4
methyl iodide

: 624-89-5
Ethyl methyl sulfide

Conditions

Conditions	Yield
With potassium hydroxide; dimethyl sulfoxide for 2h;	88%

: 83318-99-4
1-Methyl-2-methylsulfanyl-4,6-diphenyl-pyridinium; iodide

: 811-51-8
sodium thioethylate

A: 624-89-5
Ethyl methyl sulfide

B: 76950-91-9
2-Methylthio-4,6-diphenylpyridine

Conditions

Conditions	Yield
at 190℃; for 1h;	A 85% B n/a

...Expand

: 67-68-5
dimethyl sulfoxide

: 75-08-1
ethanethiol

: 624-89-5
Ethyl methyl sulfide

Conditions

Conditions	Yield
With sodium hydroxide at 125℃; for 7h;	2.4%

: 110-81-6
Diethyl disulfide

A: 624-89-5
Ethyl methyl sulfide

B: 75-08-1
ethanethiol

Conditions

Conditions	Yield
durch Penicillium brevicaule Saccardo;

: 74-93-1
methylthiol

: 546-74-7
sodium ethyl sulfate

: 624-89-5
Ethyl methyl sulfide

Conditions

Conditions	Yield
With potassium hydroxide

: 75-18-3
dimethylsulfide

: 352-93-2
diethyl sulphide

: 624-89-5
Ethyl methyl sulfide

Conditions

Conditions	Yield
With iodine
With aluminum oxide at 270 - 380℃; under 16274.9 Torr; Reagent/catalyst; Temperature; Pressure;

: 352-93-2
diethyl sulphide

: 624-89-5
Ethyl methyl sulfide

Conditions

Conditions	Yield
durch Einw.von Brotkulturen von Penicillium brevicaule Saccardo;

: 77-78-1
dimethyl sulfate

: 811-51-8
sodium thioethylate

: 624-89-5
Ethyl methyl sulfide

Conditions

Conditions	Yield
im Druckgefaess;

: 546-74-7
sodium ethyl sulfate

: 75-08-1
ethanethiol

: 624-89-5
Ethyl methyl sulfide

Conditions

Conditions	Yield
With potassium hydroxide

: 75-08-1
ethanethiol

: 624-89-5
Ethyl methyl sulfide

Conditions

Conditions	Yield
in Kulturen von Penicillium brevicaule Saccardo;
durch Einw.von Brotkulturen von Penicillium brevicaule Saccardo;

: 74-88-4
methyl iodide

: 811-51-8
sodium thioethylate

: 624-89-5
Ethyl methyl sulfide

: 917-64-6
methyl magnesium iodide

: 1669-98-3
Ethyl methyl sulfoxide

A: 75-18-3
dimethylsulfide

B: 624-89-5
Ethyl methyl sulfide

C: 352-93-2
diethyl sulphide

Conditions

Conditions	Yield
With methyllithium In diethyl ether at 36℃; for 5h; Product distribution; other reagents ratios;	A 7 % Chromat. B 7 % Chromat. C 18 % Chromat.

...Expand

: 74-93-1
methylthiol

: 75-00-3
chloroethane

: 624-89-5
Ethyl methyl sulfide

: 2373-51-5
chloro-methylsulfanyl-methane

: 925-90-6
ethylmagnesium bromide

A: 75-18-3
dimethylsulfide

B: 624-89-5
Ethyl methyl sulfide

C: 3877-15-4
1-(methylthio)-propane

D: 4110-50-3
ethyl propyl sulfide

Conditions

Conditions	Yield
In diethyl ether at 36℃; for 5h; Product distribution;	A 20 % Chromat. B 3 % Chromat. C 54 % Chromat. D 2 % Chromat.

...Expand

: 2373-51-5
chloro-methylsulfanyl-methane

: 811-49-4
ethyllithium

A: 75-18-3
dimethylsulfide

B: 624-89-5
Ethyl methyl sulfide

C: 3877-15-4
1-(methylthio)-propane

D: 1618-26-4
2,4-dithiapentane

Conditions

Conditions	Yield
In diethyl ether at 36℃; for 5h; Product distribution;	A 11 % Chromat. B 5 % Chromat. C 10 % Chromat. D 23 % Chromat.

...Expand

: 1669-98-3
Ethyl methyl sulfoxide

: 925-90-6
ethylmagnesium bromide

A: 624-89-5
Ethyl methyl sulfide

B: 352-93-2
diethyl sulphide

C: 4110-50-3
ethyl propyl sulfide

Conditions

Conditions	Yield
With lithium diethylamide In diethyl ether at 36℃; for 5h; Product distribution; other reagents, reagents ratios;	A 11 % Chromat. B 3 % Chromat. C 68 % Chromat.

...Expand

: 1669-98-3
Ethyl methyl sulfoxide

: 917-54-4
methyllithium

A: 75-18-3
dimethylsulfide

B: 624-89-5
Ethyl methyl sulfide

Conditions

Conditions	Yield
In diethyl ether at 36℃; for 5h; Product distribution; other reagents ratios;	A 3 % Chromat. B 2 % Chromat.

...Expand

: 1669-98-3
Ethyl methyl sulfoxide

: 811-49-4
ethyllithium

A: 624-89-5
Ethyl methyl sulfide

B: 352-93-2
diethyl sulphide

Conditions

Conditions	Yield
In diethyl ether at 36℃; for 5h; Product distribution;	A 12 % Chromat. B 2 % Chromat.

...Expand

: 75-03-6
ethyl iodide

: 5188-07-8
sodium thiomethoxide

: 624-89-5
Ethyl methyl sulfide

Conditions

Conditions	Yield
In ethanol

: 557-18-6
diethylmagnesium

: 67-68-5
dimethyl sulfoxide

A: 75-18-3
dimethylsulfide

B: 624-89-5
Ethyl methyl sulfide

C: 3877-15-4
1-(methylthio)-propane

D: 4110-50-3
ethyl propyl sulfide

Conditions

Conditions	Yield
In diethyl ether at 36℃; for 5h; Product distribution; reagents ratios;	A 21 % Chromat. B 6 % Chromat. C 60 % Chromat. D 6 % Chromat.

...Expand

: 925-90-6
ethylmagnesium bromide

: 67-68-5
dimethyl sulfoxide

A: 75-18-3
dimethylsulfide

B: 624-89-5
Ethyl methyl sulfide

C: 3877-15-4
1-(methylthio)-propane

D: 4110-50-3
ethyl propyl sulfide

E: 1618-26-4
2,4-dithiapentane

Conditions

Conditions	Yield
With magnesium bromide In diethyl ether at 36℃; for 5h; Product distribution; other reagent, reagents ratios;	A 13 % Chromat. B 4 % Chromat. C 8 % Chromat. D 1 % Chromat. E 11 % Chromat.

...Expand

: 811-49-4
ethyllithium

: 67-68-5
dimethyl sulfoxide

A: 75-18-3
dimethylsulfide

B: 624-89-5
Ethyl methyl sulfide

C: 3877-15-4
1-(methylthio)-propane

D: 1618-26-4
2,4-dithiapentane

Conditions

Conditions	Yield
In diethyl ether at 36℃; for 5h; Product distribution;	A 22 % Chromat. B 5 % Chromat. C 7 % Chromat. D 13 % Chromat.

...Expand

: 61192-31-2, 56648-67-0
(CH3)S(CH2)(1-)

: 594-09-2
trimethylphosphane

A: 75-18-3
dimethylsulfide

B: 624-89-5
Ethyl methyl sulfide

C: 34557-54-5
methane

D: 31386-70-6
C2H6P(1-)

E: 119405-80-0
C3H8P(1-)

F: C4H10PS(1-)

Conditions

Conditions	Yield
at 24.9℃; under 0.3 Torr; Product distribution; Mechanism;

...Expand

: 3085-30-1
aluminum tri-n-butoxide

: 75-08-1
ethanethiol

methyl-phenyl-triazene: methyl-phenyl-triazene

: 624-89-5
Ethyl methyl sulfide

...Expand

methyldiethyl sulfonium iodide: methyldiethyl sulfonium iodide

: 624-89-5
Ethyl methyl sulfide

Conditions

Conditions	Yield
With sodium hydroxide

: 74-93-1
methylthiol

: 74-85-1
ethene

carbon monoxide: carbon monoxide

A: 624-89-5
Ethyl methyl sulfide

B: 3268-49-3
3-(methylsulfenyl)propanal

Conditions

Conditions	Yield
With di-tert-butyl peroxide at 130℃; under 2206520 Torr;
With di-tert-butyl peroxide at 130℃; under 2206520 Torr;

...Expand

: 624-89-5
Ethyl methyl sulfide

: 63632-65-5
11-iodo-undecanoic acid

: (10-Carboxy-decyl)-ethyl-methyl-sulfonium; perchlorate

Conditions

Conditions	Yield
With silver perchlorate In acetonitrile for 72h; Ambient temperature;	99%

: 624-89-5
Ethyl methyl sulfide

: C25H23NO2S

: C25H23NO2S

Conditions

Conditions	Yield
With n-butyllithium; C23H25NO2 In 5,5-dimethyl-1,3-cyclohexadiene; benzene at -20℃; for 10h; Reagent/catalyst; Time; enantioselective reaction;	98%

: 624-89-5
Ethyl methyl sulfide

: 436799-32-5
5-bromo-2(trifluoromethyl)pyridine

: (±)5-(1-(methylthio)ethyl)-2-trifluoromethyl pyridine

Conditions

Conditions	Yield
With triethylamine In nitrobenzene; toluene at 125 - 149℃; under 1900.13 - 4560.31 Torr; for 14.6667h; Temperature; Pressure; Inert atmosphere;	97.6%

: 873107-98-3
5-iodo-2-(trifluoromethyl)pyridine

: 624-89-5
Ethyl methyl sulfide

: (±)5-(1-(methylthio)ethyl)-2-trifluoromethyl pyridine

Conditions

Conditions	Yield
With triethylamine In 5,5-dimethyl-1,3-cyclohexadiene at 135 - 155℃; under 2280.15 - 5320.36 Torr; for 15.75h; Inert atmosphere;	97.1%

: 624-89-5
Ethyl methyl sulfide

: 1669-98-3
Ethyl methyl sulfoxide

Conditions

Conditions	Yield
With dihydrogen peroxide In neat (no solvent) at 20℃; for 1h; chemoselective reaction;	97%
With dihydrogen peroxide In neat (no solvent) at 20℃; for 0.383333h; chemoselective reaction;	92%
With dihydrogen peroxide In neat (no solvent) at 20℃; for 0.416667h; Green chemistry; chemoselective reaction;	91%

: 624-89-5
Ethyl methyl sulfide

: C26H25NO2S

A: C26H25NO2S

B: C26H25NO2S

Conditions

Conditions	Yield
With n-butyllithium; C23H25NO2 In 5,5-dimethyl-1,3-cyclohexadiene; benzene at -20℃; for 5h; enantioselective reaction;	A 97% B n/a

...Expand

: 624-89-5
Ethyl methyl sulfide

: 594-43-4
ethyl methyl sulfone

Conditions

Conditions	Yield
With dihydrogen peroxide In methanol; dichloromethane; water at 20℃; for 2.5h;	96.2%
With dihydrogen peroxide; acetic acid at 50 - 75℃; Autoclave;	91.2%
With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid In dichloromethane for 16h;	75%

: 349-94-0
3-chloro-6-(trifluoromethyl)pyridine

: 624-89-5
Ethyl methyl sulfide

: (±)5-(1-(methylthio)ethyl)-2-trifluoromethyl pyridine

Conditions

Conditions	Yield
With ethylenediamine In toluene; benzene at 110 - 140℃; under 1520.1 - 3040.2 Torr; for 10.5h; Inert atmosphere;	96.2%

: 624-89-5
Ethyl methyl sulfide

: C20H21NO2S

A: C20H21NO2S

B: C20H21NO2S

Conditions

Conditions	Yield
With n-butyllithium; C23H25NO2 In 5,5-dimethyl-1,3-cyclohexadiene; benzene at -20℃; for 5h; enantioselective reaction;	A n/a B 96%

...Expand

: 67969-82-8
tetrafluoroboric acid diethyl ether

: (η5-C5H5)(Me)(NO)(PPh3)rhenium(II)

: 624-89-5
Ethyl methyl sulfide

: {(η5-cyclopentadienyl)(NO)(PPh3)(ethyl methyl sulfide)rhenium}BF4

Conditions

Conditions	Yield
In chlorobenzene a Schlenk flask charged with Re complex and PhCl, cooled to -45°C, HBF4OEt2 added with stirring; after 10 min, sulfide added; after 15 min the cold bath removed; reacted for 5 h; ether added, ppt. filtered off, washed (ether), dried (vac.); elem. anal.;	93%

...Expand

: 624-89-5
Ethyl methyl sulfide

: 65-85-0
benzoic acid

: (ethylthio)methyl benzoate

Conditions

Conditions	Yield
With tetrabutylammonium tetrafluoroborate In methanol; acetonitrile at 20℃; for 6h; Inert atmosphere; Electrochemical reaction;	86%

: 92695-35-7
(η5-cyclopentadienyl)Re(NO)(P(C6H5)3)(CF3SO3)

: 624-89-5
Ethyl methyl sulfide

: [(η5-C5H5)Re(NO)(PPh3)(S(Me)Et)]TfO

Conditions

Conditions	Yield
In dichloromethane stirred for 12 h at room temp.; solvent removed in vacuo, CH2Cl2 and ether added with stirring, washed with ether, dissolved in THF, layered with ether, elem. anal.;	81%

: 624-89-5
Ethyl methyl sulfide

: hexacarbonyl(2-propynylium)dicobalt tetrafluoroborate

: {Co2(CO)6(CHCCH2S(CH3)(C2H5))}(1+)*BF4(1-) = {Co2(CO)6(CHCCH2S(CH3)(C2H5))}BF4

Conditions

Conditions	Yield
In dichloromethane (Ar); addn. of a soln. of an excess of SMeEt to a suspn. of Co-complex; stirring for 1 h; addn. of diethyl ether; pptn.; washing with diethyl ether; recrystn. from CH2Cl2/diethyl ether;	80%

: 624-89-5
Ethyl methyl sulfide

: 79-10-7
acrylic acid

: 878782-37-7
EMSP*HCl

Conditions

Conditions	Yield
With hydrogenchloride In water at 80℃; for 2h;	76%

: 7681-65-4
copper(l) iodide

: 624-89-5
Ethyl methyl sulfide

: [(MeSEt)3{Cu4(μ3-I)4}]n

Conditions

Conditions	Yield
In n-heptane for 2h; Schlenk technique;	76%

: 624-89-5
Ethyl methyl sulfide

: C14H20B9(1-)*C4H12N(1+)

: C17H27B9S

Conditions

Conditions	Yield
With lithium perchlorate In water; acetonitrile at 20℃; for 6h; Electrochemical reaction; Inert atmosphere; Schlenk technique;	75%

: 624-89-5
Ethyl methyl sulfide

A: 1669-98-3
Ethyl methyl sulfoxide

B: 594-43-4
ethyl methyl sulfone

Conditions

Conditions	Yield
With C30H24N2O7W; dihydrogen peroxide In dichloromethane; water for 1h; Reflux;	A 30% B 70%
With dihydrogen peroxide; [MoO(O2)2(C9H6ON)][PPh4] In dichloromethane at 40℃; for 1h; Product distribution; Further Variations:; Catalysts; Reagents;	A 50 % Chromat. B 48 % Chromat.
With tert.-butylhydroperoxide; aluminum tri-tert-butoxide In benzene	A n/a B 20 % Chromat.

: 624-89-5
Ethyl methyl sulfide

: 7787-70-4
copper(I) bromide

: 4Cu(1+)*4Br(1-)*4C3H8S

Conditions

Conditions	Yield
In n-heptane for 5h; Schlenk technique;	68%

: 7681-65-4
copper(l) iodide

: 624-89-5
Ethyl methyl sulfide

: 75-05-8
acetonitrile

: [(MeSEt)2{Cu4(μ3-I)2(μ2-I)2}(MeCN)2]n

Conditions

Conditions	Yield
for 2h; Schlenk technique;	68%

...Expand

: 624-89-5
Ethyl methyl sulfide

: 74-97-5
chlorobromomethane

: 121424-78-0
1,21,23,25-tetrakis(2-phenylethyl)-2,20:3,19-dimetheno-1H,21H,23H,25H-bis[1,3]dioxocino[5,4-i:5',4'-i']benzo[1,2-d:5,4-d']bis[1,3]benzodioxocin-7,11,15,28-tetrol

: C132H112O24*C3H8S

Conditions

Conditions	Yield
With 1-methyl-pyrrolidin-2-one; potassium carbonate at 60℃; for 48h;	67%

...Expand

: 1001180-89-7
tert-butyl 4-(5-vinyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazine-1-carboxylate

: 624-89-5
Ethyl methyl sulfide

: 1001180-91-1
tert-butyl 4-(5-(hydroxymethyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazine-1-carboxylate

Conditions

Conditions	Yield
Stage #1: tert-butyl 4-(5-vinyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazine-1-carboxylate With ozone In dichloromethane at -78℃; for 0.25h; Stage #2: Ethyl methyl sulfide at 20℃; for 1h; Stage #3: With methanol; sodium tetrahydroborate at 0℃; for 20h;	55%

: 550-44-7
N-methylphthalimide

: 624-89-5
Ethyl methyl sulfide

A: 143142-80-7
3-hydroxy-3-(ethylthiomethyl)-2-methyl-2,3-dihydro-1H-isoindol-1-one

: 143142-81-8
erythro-3-hydroxy-3-<1-(methylthio)ethyl>-2-methyl-2,3-dihydro-1H-isoindol-1-one

: 143142-82-9
threo-3-hydroxy-3-<1-(methylthio)ethyl>-2-methyl-2,3-dihydro-1H-isoindol-1-one

Conditions

Conditions	Yield
In acetonitrile for 2.5h; Ambient temperature; Irradiation;	A 52% B 15% C 19%

...Expand

: 624-89-5
Ethyl methyl sulfide

: 55962-05-5
[N-(p-tolylsulfonyl)imino]phenyliodinane

: 21992-47-2
S-ethyl-S-methyl-N-(toluene-4-sulfonyl)-sulfimide

Conditions

Conditions	Yield
copper(I) triflate In acetonitrile at 25℃; for 28h;	50%
With copper(I) triflate In acetonitrile at 25℃; for 28h;	50%

: 624-89-5
Ethyl methyl sulfide

: (C5H5Mo)2(S2CH2)(SCH3)(S(CH3)2)(1+)*CF3SO3(1-)={(C5H5Mo)2(S2CH2)(SCH3)(S(CH3)2)}CF3SO3

: (C5H5Mo)2(S2CH2)(SCH3)(SCH3(C2H5))(1+)*CF3SO3(1-)={(C5H5Mo)2(S2CH2)(SCH3)(SCH3(C2H5))}CF3SO3

Conditions

Conditions	Yield
In acetonitrile 50-60°C, 10 days (sealed tube, vac.); solvent removal (vac.), chromy. (Al2O3, hexanes/CH2Cl2, then 5% EtOH in CH2Cl2), drying;	41%

: 624-89-5
Ethyl methyl sulfide

: 622-37-7
Phenyl azide

A: 3463-02-3
4-(ethylthio)aniline

B: 13920-91-7
2-(ethylthio)aniline

C: 2987-53-3
2-(Methylthio)aniline

D: 104-96-1
4-methylsulfanylaniline

Conditions

Conditions	Yield
With trifluorormethanesulfonic acid; trifluoroacetic acid Ambient temperature;	A 11% B 38% C 5% D 4%

...Expand

Methylthioethane Specification

The Ethane, (methylthio)-, with CAS registry number 624-89-5, belongs to the following product categories: (1)Organic Building Blocks; (2)Sulfides/Disulfides; (3)Sulfur Compounds. It has the systematic name of (methylsulfanyl)ethane. This chemical is a kind of clear colorless liquid. The main use of this chemical is organic synthesis.

Physical properties of Ethane, (methylthio)-L: (1)ACD/LogP: 1.42; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.42; (4)ACD/LogD (pH 7.4): 1.42; (5)ACD/BCF (pH 5.5): 7.05; (6)ACD/BCF (pH 7.4): 7.05; (7)ACD/KOC (pH 5.5): 140.85; (8)ACD/KOC (pH 7.4): 140.85; (9)#H bond acceptors: 0; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 1; (12)Polar Surface Area: 25.3 Å²; (13)Index of Refraction: 1.433; (14)Molar Refractivity: 23.94 cm³; (15)Molar Volume: 92 cm³; (16)Polarizability: 9.49×10^-24cm³; (17)Surface Tension: 23.2 dyne/cm; (18)Enthalpy of Vaporization: 29.53 kJ/mol; (19)Vapour Pressure: 186 mmHg at 25°C.

Preparation: this chemical can be prepared by iodomethane and ethanethiol. This reaction will need reagents KOH, DMSO. The reaction time is 2 hour(s). The yield is about 88%.

Uses of p-Chloropropiophenone: it can be used to produce methanesulfinyl-ethane. This reaction will need reagents 35percent aq. H₂O₂ and solvent methanol. The reaction time is 2 hour(s). The yield is about 50%.

When you are using this chemical, please be cautious about it as the following:
The Ethane, (methylthio)- is highly flammable, so keep it away from sources of ignition. When use this chemical, do not breathe vapour and avoid contact with skin and eyes.

You can still convert the following datas into molecular structure:
(1)SMILES: S(CC)C
(2)InChI: InChI=1/C3H8S/c1-3-4-2/h3H2,1-2H3
(3)InChIKey: WXEHBUMAEPOYKP-UHFFFAOYAC
(4)Std. InChI: InChI=1S/C3H8S/c1-3-4-2/h3H2,1-2H3
(5)Std. InChIKey: WXEHBUMAEPOYKP-UHFFFAOYSA-N

Product Name

Methylthioethane

Synthetic route

Methylthioethane Specification

Related Products

Hot Products