N-(9-Fluorenylmethoxycarbonyloxy)succinimide supplier

Name
N-(9-Fluorenylmethoxycarbonyloxy)succinimide
EINECS 433-520-5
CAS No. 82911-69-1
Article Data9
CAS DataBase
Density 1.42 g/cm³
Solubility
Melting Point 150-153 °C(lit.)
Formula C₁₉H₁₅NO₅
Boiling Point 494.3 °C at 760 mmHg
Molecular Weight 337.332
Flash Point 252.7 °C
Transport Information
Appearance White powder
Safety 22-24/25-26/37/39-26
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms 9-Fluorenylmethylsuccinimidyl carbonate;2,5-Pyrrolidinedione, 1-(((9H-fluoren-9-ylmethoxy)carbonyl)oxy)-;Fmoc-OSu;N-(9-FluorenylmethoxyCar;(2,5-dioxopyrrolidin-1-yl) 9H-fluoren-9-ylmethyl carbonate;Fmoc-onsu;N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide;Fmoc;N-(9-FluorenylmethoxyCarbonyloxy) Succinimide;N-(9-Fluorenylmethoxycarbonyloxy)-succinimide;Fluoren-9-ylmethyl succinimidyl carbonate;Fmoc-OSu (9-Fluorenylmethyl succinimidyl carbonate);Carbonic acid 2,5-dioxo-pyrrolidin-1-yl ester 9H-fluoren-9-ylmethyl ester;9-Fluorenylmethyl succinimidyl carbonate;Fmoc-ONSu;N-(9-Fluorenylmethoxycarbonyloxy) Succinimide;9-Fluorenylmethyl N-succinimidyl carbonate;
PSA 72.91000
LogP 2.95400

Synthetic route

: 6066-82-6
1-hydroxy-pyrrolidine-2,5-dione

: 28920-43-6
(fluorenylmethoxy)carbonyl chloride

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

Conditions

Conditions	Yield
With triethylamine In 1,4-dioxane for 1h; Ambient temperature;	96%
With sodium carbonate In water; toluene at 25 - 30℃; for 2h; Reagent/catalyst; Solvent;	56.3%
With sodium carbonate In water; acetone for 0.5h; Acylation;

: 28920-43-6
(fluorenylmethoxy)carbonyl chloride

: 82911-72-6
dicyclohexylamine salt of N-hydroxysuccinimide

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

Conditions

Conditions	Yield
In chloroform	90%

: C16H26N2O3

: 28920-43-6
(fluorenylmethoxy)carbonyl chloride

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

Conditions

Conditions	Yield
In chloroform	90%

: 15149-73-2
2,5-dioxopyrrolidin-1-yl carbonochloridate

: 24324-17-2
9-Fluorenylmethanol

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

Conditions

Conditions	Yield
With pyridine In dichloromethane for 5h; Ambient temperature;	72%

: 101-83-7
N-cyclohexyl-cyclohexanamine

chromium oxide activated nickel catalyst: chromium oxide activated nickel catalyst

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 95 percent / acetone 2: 90 percent / CHCl3 View Scheme

: 56-45-1
L-serin

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 73724-45-5
N-(9H-fluoren-9-ylmethoxycarbonyl)-L-serine

Conditions

Conditions	Yield
With sodium hydrogencarbonate	100%
With sodium carbonate In 1,4-dioxane	97%
With sodium hydrogencarbonate In water; acetonitrile	94%

: 72-19-5
L-threonine

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 73731-37-0
Fmoc-Thr-OH

Conditions

Conditions	Yield
With sodium hydrogencarbonate	100%
Stage #1: L-threonine; N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide With sodium carbonate In 1,4-dioxane; water at 20℃; Inert atmosphere; Stage #2: With hydrogenchloride In water pH=4;	100%
With sodium hydrogencarbonate In acetone	97%

: 5680-80-8
methyl (2S)-2-amino-3-hydroxypropanoate hydrochloride

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 82911-78-2
N-[(9-fluorenylmethoxy)carbonyl]-L-serine methyl ester

Conditions

Conditions	Yield
Stage #1: methyl (2S)-2-amino-3-hydroxypropanoate hydrochloride With sodium hydrogencarbonate In 1,4-dioxane; water at 20℃; for 0.25h; Stage #2: N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide In 1,4-dioxane; water at 20℃; for 14h;	100%
Stage #1: methyl (2S)-2-amino-3-hydroxypropanoate hydrochloride With sodium hydrogencarbonate In 1,4-dioxane; water at 20℃; for 0.25h; Stage #2: N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide In 1,4-dioxane; water at 20℃; for 14h;	100%
Stage #1: methyl (2S)-2-amino-3-hydroxypropanoate hydrochloride With sodium hydrogencarbonate In 1,4-dioxane at 20℃; for 0.5h; Stage #2: N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide In 1,4-dioxane at 20℃; for 24h;	97%

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 117286-86-9
3-(3-(amino-4-methoxyphenylmethyl)-4-methoxyphenyl)propionic acid

: 117286-85-8
3-(α-fluoren-9-ylmethoxycarbonylamino-4-methoxybenzyl)-4-methoxyphenylpropionic acid

Conditions

Conditions	Yield
With triethylamine In N,N-dimethyl-formamide for 1h; Ambient temperature;	100%

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 1397-89-3
AmBisome

: 127970-81-4
3′-N-Fmoc-AmB

Conditions

Conditions	Yield
With pyridine In N,N-dimethyl-formamide at 20℃; for 18h;	100%
With pyridine In methanol; N,N-dimethyl-formamide at 23℃; for 4h;	99%
With pyridine In methanol; N,N-dimethyl-formamide at 20℃; for 12h;	95%

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: (S)-2-Amino-4-(2,4,6-trimethoxy-benzylsulfamoyl)-butyric acid

: (S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-4-(2,4,6-trimethoxy-benzylsulfamoyl)-butyric acid

Conditions

Conditions	Yield
With sodium hydrogencarbonate In water; acetone for 12h; Ambient temperature;	100%

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 152871-80-2
(R)-2-Amino-3-(2-tert-butoxycarbonylamino-ethylsulfamoyl)-propionic acid

: (R)-3-(2-tert-Butoxycarbonylamino-ethylsulfamoyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionic acid

Conditions

Conditions	Yield
With sodium hydrogencarbonate In water; acetone for 12h; Ambient temperature;	100%

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 152871-82-4
(R)-2-Amino-4-(2-tert-butoxycarbonylamino-ethylsulfamoyl)-butyric acid

: (R)-4-(2-tert-Butoxycarbonylamino-ethylsulfamoyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-butyric acid

Conditions

Conditions	Yield
With sodium hydrogencarbonate In water; acetone for 12h; Ambient temperature;	100%

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 2450-71-7
Propargylamine

: 127896-08-6
Fmoc-N-propargylamine

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 1h; Cooling with ice;	100%
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃;	100%
With dmap In dichloromethane at 0 - 20℃; for 4h;	94%

: 16874-12-7
Tyr(tBu)

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 133852-23-0
(S)-tert-butyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-hydroxyphenyl)propanoate

Conditions

Conditions	Yield
Stage #1: Tyr(tBu); N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide With sodium hydrogencarbonate In 1,4-dioxane; water at 20℃; for 18h; Stage #2: With hydrogenchloride; water In 1,4-dioxane	100%
With N-ethyl-N,N-diisopropylamine In acetone at 22 - 25℃;	95.8%
With N-ethyl-N,N-diisopropylamine In acetone at 20℃; for 12h;	95.8%

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 31456-71-0
(2S)-1,2,3,6-tetrahydropyridine-2-carboxylic acid

: 207733-59-3
(S)-3,6-Dihydro-2H-pyridine-1,2-dicarboxylic acid 1-(9H-fluoren-9-ylmethyl) ester

Conditions

Conditions	Yield
With sodium hydroxide; sodium hydrogencarbonate	100%

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: (3S,6R,8aR)-6-Amino-5-oxo-octahydro-indolizine-3-carboxylic acid

: 326490-44-2
(3R,6R,9S)-1-aza-9-carboxy-3-(9'-fluorenylmethoxycarbonylamino)-2-oxo-bicyclo[4.3.0]nonane

Conditions

Conditions	Yield
Stage #1: (3S,6R,8aR)-6-Amino-5-oxo-octahydro-indolizine-3-carboxylic acid With trifluoroacetic acid In dichloromethane at 20℃; for 1h; Stage #2: N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide With sodium carbonate In tetrahydrofuran; water at 20℃; for 3h; Further stages.;	100%

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: (3S,6S,8aR)-6-Amino-5-oxo-octahydro-indolizine-3-carboxylic acid

: 326490-43-1
(2S,6R,9S)-2-oxo-3-(9-fluorenyloxycarbonylamino)-1-azabicyclo[4.2.0]nonane-9-carboxylic acid

Conditions

Conditions	Yield
Stage #1: (3S,6S,8aR)-6-Amino-5-oxo-octahydro-indolizine-3-carboxylic acid With trifluoroacetic acid In dichloromethane at 20℃; for 1h; Stage #2: N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide With sodium carbonate In tetrahydrofuran; water at 20℃; for 3h; Further stages.;	100%
With sodium carbonate In 1,4-dioxane; water

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: (3S,6R,8aS)-6-Amino-5-oxo-octahydro-indolizine-3-carboxylic acid

: 326490-42-0
(3R,6S,9S)-1-aza-9-carboxy-3-(9'-fluorenylmethoxycarbonylamino)-2-oxo-bicyclo[4.3.0]nonane

Conditions

Conditions	Yield
Stage #1: (3S,6R,8aS)-6-Amino-5-oxo-octahydro-indolizine-3-carboxylic acid With trifluoroacetic acid In dichloromethane at 20℃; for 1h; Stage #2: N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide With sodium carbonate In tetrahydrofuran; water at 20℃; for 3h; Further stages.;	100%

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 934660-55-6
(3S,6S,8aS)-6-Amino-5-oxo-octahydro-indolizine-3-carboxylic acid

: 326490-41-9
(3S,6S,9S)-2-oxo-3-(N-(9-fluorenylmethoxycarbonyl)amino)-1-azabicyclo[4.3.0]nonane-9-carboxylic acid

Conditions

Conditions	Yield
Stage #1: (3S,6S,8aS)-6-Amino-5-oxo-octahydro-indolizine-3-carboxylic acid With trifluoroacetic acid In dichloromethane at 20℃; for 1h; Stage #2: N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide With sodium carbonate In tetrahydrofuran; water at 20℃; for 3h; Further stages.;	100%
With sodium carbonate In 1,4-dioxane; water	265 mg

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: (3S,6R,9aR)-6-Amino-5-oxo-octahydro-pyrrolo[1,2-a]azepine-3-carboxylic acid

: 337513-07-2
(3R,7R,10S)-1-aza-10-carboxy-3-(9'-fluorenylmethoxycarbonylamino)-2-oxo-bicyclo[5.3.0]decane

Conditions

Conditions	Yield
Stage #1: (3S,6R,9aR)-6-Amino-5-oxo-octahydro-pyrrolo[1,2-a]azepine-3-carboxylic acid With trifluoroacetic acid In dichloromethane at 20℃; for 1h; Stage #2: N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide With sodium carbonate In tetrahydrofuran; water at 20℃; for 3h; Further stages.;	100%

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: (3S,6S,9aR)-6-Amino-5-oxo-octahydro-pyrrolo[1,2-a]azepine-3-carboxylic acid

: 270585-84-7
(3S,7R,10S)-2-oxo-3-N-(9-fluorenylmethyloxycarbonyl)amino-1-azabicyclo[5.3.0]decane-10-carboxylic acid

Conditions

Conditions	Yield
Stage #1: (3S,6S,9aR)-6-Amino-5-oxo-octahydro-pyrrolo[1,2-a]azepine-3-carboxylic acid With trifluoroacetic acid In dichloromethane at 20℃; for 1h; Stage #2: N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide With sodium carbonate In tetrahydrofuran; water at 20℃; for 3h; Further stages.;	100%

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: (3S,6R,9aS)-6-Amino-5-oxo-octahydro-pyrrolo[1,2-a]azepine-3-carboxylic acid

: 326490-45-3
(3R,7S,10S)-1-aza-10-carboxy-3-(9'-fluorenylmethoxycarbonylamino)-2-oxo-bicyclo[5.3.0]decane

Conditions

Conditions	Yield
Stage #1: (3S,6R,9aS)-6-Amino-5-oxo-octahydro-pyrrolo[1,2-a]azepine-3-carboxylic acid With trifluoroacetic acid In dichloromethane at 20℃; for 1h; Stage #2: N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide With sodium carbonate In tetrahydrofuran; water at 20℃; for 3h; Further stages.;	100%

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: (3S,6S,9aS)-6-Amino-5-oxo-octahydro-pyrrolo[1,2-a]azepine-3-carboxylic acid

: 220719-79-9
(3S,7S,10S)-2-oxo-3-N-(9-fluorenylmethyloxycarbonyl)amino-1-azabicyclo[5.3.0]decane-10-carboxylic acid

Conditions

Conditions	Yield
Stage #1: (3S,6S,9aS)-6-Amino-5-oxo-octahydro-pyrrolo[1,2-a]azepine-3-carboxylic acid With trifluoroacetic acid In dichloromethane at 20℃; for 1h; Stage #2: N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide With sodium carbonate In tetrahydrofuran; water at 20℃; for 3h; Further stages.;	100%

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: (2S,3S)-2-amino-3-(1-(tert-butoxycarbonyl)-1H-indol-3-yl)butanoic acid

: (2S,3S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-(tert-butoxycarbonyl)-1H-indol-3-yl)butanoic acid

Conditions

Conditions	Yield
With triethylamine In methanol	100%

: 2521-84-8
(S)-2-amino-2-cyclopentylacetic acid

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-cyclopentylacetic acid

Conditions

Conditions	Yield
With sodium carbonate In 1,4-dioxane; water	100%

: 1668-10-6
glycinamide hydrochloride

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 115057-37-9
Fmoc-Gly-NH2

Conditions

Conditions	Yield
With sodium carbonate In acetone at 20℃; for 1h;	100%
With sodium hydrogencarbonate In acetone at 20℃; for 2h; pH=7;	80%
With sodium carbonate In water; acetone at 0 - 20℃; for 1.5h;	72%

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 714230-15-6
N-α-tert-butyloxycarbonyl-(2S,4R)-2-tert-butyloxycarbonylmethyl-4-(adenin-9'-yl)-pyrrolidine

: 714230-17-8
N-α-9-fluorenylmethoxycarbonyl-(2S,4R)-2-hydroxycarbonylmethoxymethyl-4-(adenin-9'-yl)-pyrrolidine

Conditions

Conditions	Yield
Stage #1: N-α-tert-butyloxycarbonyl-(2S,4R)-2-tert-butyloxycarbonylmethyl-4-(adenin-9'-yl)-pyrrolidine With hydrogen bromide; acetic acid at 20℃; for 1h; Stage #2: N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide With sodium hydrogencarbonate In acetonitrile at 20℃;	100%

: 3-amino-3-deoxy-1,2-O-isopropylidene-α-L-ribofuranose

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 928306-69-8
3-deoxy-3-(9-fluorenylmethoxycarbonyl)amino-1,2-O-isopropylidene-α-L-ribofuranose

Conditions

Conditions	Yield
With sodium hydrogencarbonate In water; acetone at 20℃; for 1h;	100%

: (2S,4S)-4-diphenylphosphinothioyl-proline hydrochloride

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 178158-98-0
(2S,4S)-N-fluorenylmethoxycarbonyl-2-carboxy-4-diphenylphosphinothioyl-pyrrolidine

Conditions

Conditions	Yield
With sodium hydrogencarbonate In water; acetone	100%

: 13325-10-5
4-Aminobutanol

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 209115-32-2
(9H-fluoren-9-yl)methyl (4-hydroxybutyl)carbamate

Conditions

Conditions	Yield
With pyridine In methanol at 23℃; for 23h;	100%
In tetrahydrofuran; water at 20℃; Cooling with ice;	1.21 g

: 4048-33-3
6-amino-1-hexanol

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 127903-20-2
(9H-fluoren-9-yl)methyl (6-hydroxyhexyl)carbamate

Conditions

Conditions	Yield
With pyridine In methanol at 23℃; for 16h;	100%
With pyridine In methanol at 23℃;
With sodium carbonate In 1,4-dioxane; water at 20℃; for 0.5h;	11 g

: 1-amino-2-butyl-cycloprop-2-ene carboxylic acid trifluoroacetic acid salt

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 2-butyl-1-(9H-fluoren-9-ylmethoxycarbonylamino)-cycloprop-2-ene carboxylic acid

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In water; acetonitrile at 20℃; for 4h;	100%

: 2-((S)-1-{(S)-2-[(2S,3S)-2-((2S,3S)-2-{[(S)-1-((S)-2-Amino-3-phenyl-propionyl)-pyrrolidine-2-carbonyl]-amino}-3-methyl-pentanoylamino)-3-hydroxy-butyrylamino]-3-phenyl-propionyl}-pyrrolidin-2-yl)-thiazole-4-carboxylic acid ethyl ester; hydrochloride

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 2-[1-(2-{2-[2-({1-[2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenyl-propionyl]-pyrrolidine-2-carbonyl}-amino)-3-methyl-pentanoylamino]-3-hydroxy-butyrylamino}-3-phenyl-propionyl)-pyrrolidin-2-yl]-thiazole-4-carboxylic acid ethyl ester

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In dichloromethane pH=9;	100%

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 141-43-5
ethanolamine

: 105496-31-9
N-(9-fluorenylmethoxycarbonyl)-2-aminoethanol

Conditions

Conditions	Yield
With sodium hydrogencarbonate In water; acetone at 20℃; for 4h;	100%
In 1,4-dioxane; water at 20℃; for 16h;	97%
With triethylamine In tetrahydrofuran at 20℃;	93%

N-(9-Fluorenylmethoxycarbonyloxy)succinimide Specification

The 9-Fluorenylmethyl succinimidyl carbonate, with the CAS registry number 82911-69-1, is also known as 2,5-Pyrrolidinedione, 1-(((9H-fluoren-9-ylmethoxy)carbonyl)oxy)-. It belongs to the product categories of Amino Acid Derivatives; Medical Intermediates; Benzocycles; Fluorenes, Flurenones; Pyrrolidines; N-Protecting Reagents; Biochemistry; Condensation & Active Esterification; Fluorenes; Fluorenes & Fluorenones; N-Substituted Maleimides, Succinimides & Phthalimides; N-Substituted Succinimides; Peptide Synthesis; Protective Reagents (Peptide Synthesis); Synthetic Organic Chemistry; Fmoc-Amino Acid Series. Its EINECS registry number is 433-520-5. This chemical's molecular formula is and molecular weight is . Its IUPAC name is called (2,5-dioxopyrrolidin-1-yl) 9H-fluoren-9-ylmethyl carbonate.

Physical properties of 9-Fluorenylmethyl succinimidyl carbonate: (1)ACD/LogP: 2.32; (2)ACD/LogD (pH 5.5): 2.32; (3)ACD/LogD (pH 7.4): 2.32; (4)ACD/BCF (pH 5.5): 33.91; (5)ACD/BCF (pH 7.4): 33.91; (6)ACD/KOC (pH 5.5): 433.51; (7)ACD/KOC (pH 7.4): 433.51; (8)#H bond acceptors: 6; (9)#Freely Rotating Bonds: 5; (10)Index of Refraction: 1.661; (11)Molar Refractivity: 87.47 cm³; (12)Molar Volume: 236.4 cm³; (13)Surface Tension: 66.7 dyne/cm; (14)Density: 1.42 g/cm³; (15)Flash Point: 252.7 °C; (16)Enthalpy of Vaporization: 76.16 kJ/mol; (17)Boiling Point: 494.3 °C at 760 mmHg; (18)Vapour Pressure: 6.55E-10 mmHg at 25°C.

Preparation: this chemical can be prepared by N-hydroxy-succinimide and 9H-fluoren-9-ylmethyl chloroformate. This reaction is a kind of Acylation. It will need reagent Na₂CO₃ and solvent H₂O, acetone. The reaction time is 30 min.

Uses of 9-Fluorenylmethyl succinimidyl carbonate: it can be used to produce N-(9-fluorenylmethyloxycarbonyl)-L-serine methyl ester. This reaction will need reagent aq. sodium hydrogen carbonate and solvent dioxane with reaction time of 10 min. The yield is about 80%.

When you are using this chemical, please be cautious about it as the following:
This chemical may cause inflammation to the skin or other mucous membranes. It is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. Whenever you will contact it, please wear suitable protective clothing, gloves and eye/face protection.

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: C1CC(=O)N(C1=O)OC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24
(2)InChI: InChI=1S/C19H15NO5/c21-17-9-10-18(22)20(17)25-19(23)24-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16H,9-11H2
(3)InChIKey: WMSUFWLPZLCIHP-UHFFFAOYSA-N

Product Name

N-(9-Fluorenylmethoxycarbonyloxy)succinimide

Synthetic route

N-(9-Fluorenylmethoxycarbonyloxy)succinimide Specification

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