Pyridoxine hydrochloride supplier

Name
Pyridoxine hydrochloride
EINECS 200-386-2
CAS No. 58-56-0
Article Data26
CAS DataBase
Density 1.2784 (rough estimate)
Solubility 0.1 g/mL at 20 °C in water
Melting Point 214-215 °C(lit.)
Formula C₈H₁₁NO₃^.ClH
Boiling Point 491.9 °C at 760 mmHg
Molecular Weight 205.641
Flash Point 251.3 °C
Transport Information
Appearance Crystalline
Safety 26-37/39
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms 3,4-Pyridinedimethanol,5-hydroxy-6-methyl-, hydrochloride (9CI);Pyridoxol, hydrochloride (7CI,8CI);2-Methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine hydrochloride;4,5-Bis(hydroxymethyl)-2-methylpyridin-3-olhydrochloride;4,5-Bis(hydroxymethyl)-3-hydroxy-2-methylpyridine hydrochloride;5-Hydroxy-6-methyl-3,4-pyridinedimethanol hydrochloride;Aderomine hydrochloride;Aderoxin;Aderoxine;Hexabetalin;Hexavibex;Pyridipca;Pyridox;Pyridoxin hydrochloride;Pyridoxine chloride;
PSA 73.58000
LogP 0.88220

Synthetic route

: 10030-93-0
pyridoxine triacetate

: 58-56-0
pyridoxal hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In water for 2h; Heating;	98%
With hydrogenchloride; water for 2h; Heating / reflux;	72%

: 2397-71-9
5-hydroxy-6-methylpyridine-3,4-dicarboxylic acid diethyl ester

: 58-56-0
pyridoxal hydrochloride

Conditions

Conditions	Yield
Stage #1: 5-hydroxy-6-methylpyridine-3,4-dicarboxylic acid diethyl ester With sodium tetrahydroborate; iron(II) sulfate; N,N-dimethyl-aniline In tetrahydrofuran for 4h; Reflux; Stage #2: With hydrogenchloride In tetrahydrofuran at 20℃; Reagent/catalyst; Solvent;	93.4%

: 4,5-dihydroxymethyl-2-methyl-2-cyclopentenone

: 58-56-0
pyridoxal hydrochloride

Conditions

Conditions	Yield
Stage #1: 4,5-dihydroxymethyl-2-methyl-2-cyclopentenone With ozone In methanol; water at -30℃; for 3h; Stage #2: With ammonia In methanol; water at 20 - 25℃; for 3h; Stage #3: With hydrogenchloride; pyrographite In ethanol at 55 - 60℃; for 1h; Temperature; Solvent;	92%

: 2-hydroxymethyl-3-cyano-4-hydroxy-n-butyraldehyde

: 13515-97-4
methyl 2-aminopropanoate monohydrochloride

: 58-56-0
pyridoxal hydrochloride

Conditions

Conditions	Yield
Stage #1: 2-hydroxymethyl-3-cyano-4-hydroxy-n-butyraldehyde; methyl 2-aminopropanoate monohydrochloride With sodium methylate In methanol at 30 - 50℃; for 5h; Green chemistry; Stage #2: With hydrogenchloride In methanol; water for 2h; Temperature; Solvent; Reagent/catalyst; Reflux; Green chemistry;	90.5%

: 4-methyl-5-dimethyl-tert-butylsiloxyoxazole

: 4469-34-5
2-propyl-4,7-dihydro-2H-1,3-dioxepine

: 58-56-0
pyridoxal hydrochloride

Conditions

Conditions	Yield
Stage #1: 4-methyl-5-dimethyl-tert-butylsiloxyoxazole; 2-propyl-4,7-dihydro-2H-1,3-dioxepine at 115 - 120℃; for 10h; Stage #2: With water In ethanol at 20℃; for 3h; Stage #3: With hydrogenchloride In ethanol; water at 20℃; for 2h;	89.5%

: 5205-63-0
Diels-Alder adduct

: 58-56-0
pyridoxal hydrochloride

Conditions

Conditions	Yield
Stage #1: Diels-Alder adduct With hydrogenchloride In ethanol; water at 20℃; for 2h; Stage #2: In ethanol; water for 2h;	86.05%

: C8H13NO4

: 58-56-0
pyridoxal hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride; pyrographite In ethanol; water at 75 - 78℃; for 3h; Temperature;	83.5%

: 4-methyl-5-triisopropylsiloxyoxazole

: 4469-34-5
2-propyl-4,7-dihydro-2H-1,3-dioxepine

: 58-56-0
pyridoxal hydrochloride

Conditions

Conditions	Yield
Stage #1: 4-methyl-5-triisopropylsiloxyoxazole; 2-propyl-4,7-dihydro-2H-1,3-dioxepine at 115 - 120℃; for 10h; Stage #2: With water In ethanol at 20℃; for 3h; Stage #3: With hydrogenchloride In ethanol; water at 20℃; for 2h;	82.7%

: 4469-34-5
2-propyl-4,7-dihydro-2H-1,3-dioxepine

: 24201-52-3
4-methyl-5-butoxy1,3-oxazole

: 58-56-0
pyridoxal hydrochloride

Conditions

Conditions	Yield
Stage #1: 2-propyl-4,7-dihydro-2H-1,3-dioxepine; 4-methyl-5-butoxy1,3-oxazole With calcium oxide at 150℃; for 12h; Diels-Alder Cycloaddition; Stage #2: With hydrogenchloride In ethanol; water at 20 - 60℃; for 12h; Stage #3: With hydrogenchloride In water for 1h; pH=8; Reagent/catalyst; Reflux;	80%

: 5006-20-2
5-ethoxy-4-methyl-oxazole

: 4469-34-5
2-propyl-4,7-dihydro-2H-1,3-dioxepine

: 58-56-0
pyridoxal hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride Diels-Alder Cycloaddition;	78.5%

: 90330-16-8
3-amino-4,5-bis(aminomethyl)2-methylpyridine trihydrochloride

: 58-56-0
pyridoxal hydrochloride

Conditions

Conditions	Yield
With sulfuric acid; sodium nitrite In water at 90℃; for 2h;	75%

: 39984-49-1
2-Methyl-3-hydroxy-4,5-bis-(bromomethyl)-pyridine hydrobromide

: 58-56-0
pyridoxal hydrochloride

Conditions

Conditions	Yield
With water; silver(I) chloride for 0.333333h; Heating;	68%
Multi-step reaction with 2 steps 1: 2.) AcONa / 1.) DMF, 55 degC, 1 h; 2.) DMF, 85 degC, 2.5 h 2: 98 percent / 2N HCl / H2O / 2 h / Heating View Scheme

: 524-36-7
pyridoxamine dihydrochloride

: 58-56-0
pyridoxal hydrochloride

Conditions

Conditions	Yield
With sulfuric acid; water; sodium nitrite at 20 - 90℃; for 2h;	25%

: 67-03-8
Thiamine hydrochloride

: 58-56-0
pyridoxal hydrochloride

Conditions

Conditions	Yield
With N-Bs In isopropyl alcohol at 25℃; for 0.5h;

: 80095-36-9
L-1-Deoxy<1,1,1-(2)H3,(RS)-5-(2)H1>xylulose

: 58-56-0
pyridoxal hydrochloride

Conditions

Conditions	Yield
With D-glucose; Escherichia coli B WG2 Mechanism;

: 83537-53-5
3-amino-4-aminomethyl-5-hydroxymethyl-2-methylpyridine dihydrochloride

: 58-56-0
pyridoxal hydrochloride

Conditions

Conditions	Yield
With cis-nitrous acid In water at 90℃;

: Acetic acid 4-acetoxymethyl-2,5-dimethoxy-2-(1-methoxycarbonylamino-ethyl)-2,5-dihydro-furan-3-ylmethyl ester

: 58-56-0
pyridoxal hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In water Yield given;

: 7647-01-0
hydrogenchloride

: 45996-87-0
4,5-bis-aminomethyl-2-methyl-pyridin-3-ol

aqueous NaNO2: aqueous NaNO2

A: 58-56-0
pyridoxal hydrochloride

B <5-chloromethyl>-3-hydroxy-2-methyl-<4>pyridyl>-methanol: <5-chloromethyl>-3-hydroxy-2-methyl-<4>pyridyl>-methanol

...Expand

: 7647-01-0
hydrogenchloride

: 4-ethoxymethyl-5-hydroxymethyl-2-methyl-pyridin-3-ol; hydrochloride

: 58-56-0
pyridoxal hydrochloride

Conditions

Conditions	Yield
at 155 - 160℃;

: 71058-42-9
5-amino-6-methylpyridine-3,4-dicarbonitrile

: 58-56-0
pyridoxal hydrochloride

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 75 percent / conc. HCl, H2 / 5 percent Pd-C / methanol; H2O / 3.5 h / Ambient temperature 2: 75 percent / sodium nitrite, H2SO4 / H2O / 2 h / 90 °C View Scheme

: 83537-57-9
5-acetoxymethyl-3-amino-2-methylpyridine-4-carbonitrile

: 58-56-0
pyridoxal hydrochloride

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 88 percent / 1) conc. HCl, H2; 2) 0.2 N HCl / 1) 5 percent Pd-C / methanol; H2O / 1) 1 h, RT; 2) 1 h, 80 deg C 2: nitrous acid / H2O / 90 °C View Scheme

: 14496-24-3
3,4-bis(hydroxymethyl)furan

: 58-56-0
pyridoxal hydrochloride

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: 100 percent / pyridine 2: 57 percent / p-toluenesulfonic acid / 2 h / 0 - 5 °C 3: electrochemical oxidation 4: HCl / H2O View Scheme

: 30614-73-4
3,4-furan dimethanol diacetate

: 58-56-0
pyridoxal hydrochloride

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 57 percent / p-toluenesulfonic acid / 2 h / 0 - 5 °C 2: electrochemical oxidation 3: HCl / H2O View Scheme

: 79588-15-1
Acetic acid 4-acetoxymethyl-2-(1-methoxycarbonylamino-ethyl)-furan-3-ylmethyl ester

: 58-56-0
pyridoxal hydrochloride

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: electrochemical oxidation 2: HCl / H2O View Scheme

: 104307-94-0
1,3-dihydro-6-methyl-7-iodofuro(3,4-c)pyridine

: 58-56-0
pyridoxal hydrochloride

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 36 percent / Na, MeOH / CuI2 / various solvent(s) / 16 h / Heating 2: 78 percent / 48percent HBr / 2 h / Heating 3: 68 percent / H2O, AgCl / 0.33 h / Heating View Scheme

: 104307-95-1
1,3-dihydro-6-methyl-7-methoxyfuro(3,4-c)pyridine

: 58-56-0
pyridoxal hydrochloride

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 78 percent / 48percent HBr / 2 h / Heating 2: 68 percent / H2O, AgCl / 0.33 h / Heating View Scheme

: 104307-93-9
1,3-dihydro-6-methyl-7-trimethylstannylfuro(3,4-c)pyridine

: 58-56-0
pyridoxal hydrochloride

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: 99 percent / I2 / CHCl3 / 18 h / Ambient temperature 2: 36 percent / Na, MeOH / CuI2 / various solvent(s) / 16 h / Heating 3: 78 percent / 48percent HBr / 2 h / Heating 4: 68 percent / H2O, AgCl / 0.33 h / Heating View Scheme

: 1622-67-9
4,5'-O-isobutylidenepyridoxine

: 58-56-0
pyridoxal hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride; water under 300.03 Torr; for 2h; Product distribution / selectivity; Heating / reflux;
Stage #1: 4,5'-O-isobutylidenepyridoxine With hydrogenchloride; water In tetrahydrofuran at 60 - 120℃; under 150.015 Torr; for 3h; Stage #2: With pyrographite In water at 0 - 60℃; Product distribution / selectivity;

: 717916-87-5
3-isopropyl-1,5-dihydro[1,3]dioxepino-3-methyl-4-n-butoxy-7-oxa-2-azabicyclo[2.2.1]hept-2-ene

A: 58-56-0
pyridoxal hydrochloride

B: 1622-67-9
4,5'-O-isobutylidenepyridoxine

Conditions

Conditions	Yield
Stage #1: 3-isopropyl-1,5-dihydro[1,3]dioxepino-3-methyl-4-n-butoxy-7-oxa-2-azabicyclo[2.2.1]hept-2-ene With water; acetic acid In tetrahydrofuran at 60℃; under 760.051 Torr; for 4h; Stage #2: With hydrogenchloride; water In tetrahydrofuran at 0 - 60℃; for 5h; Product distribution / selectivity;
Stage #1: 3-isopropyl-1,5-dihydro[1,3]dioxepino-3-methyl-4-n-butoxy-7-oxa-2-azabicyclo[2.2.1]hept-2-ene With water In tetrahydrofuran at 60℃; under 760.051 Torr; for 4h; Stage #2: With hydrogenchloride In tetrahydrofuran at 20 - 60℃; for 5h; Product distribution / selectivity;

concentrated H2 SO4: concentrated H2 SO4

: 58-56-0
pyridoxal hydrochloride

: isopropylidene pyridoxine

Conditions

Conditions	Yield
In acetone	100%

: 58-56-0
pyridoxal hydrochloride

: 39984-50-4
4,5-bis(chloromethyl)-3-hydroxy-2-methylpyridinium chloride

Conditions

Conditions	Yield
With thionyl chloride In N,N-dimethyl-formamide for 0.5h; Reflux; Inert atmosphere;	99%
With thionyl chloride In dichloromethane; N,N-dimethyl-formamide for 12h; Reflux;	96%
With thionyl chloride; N,N-dimethyl-formamide at 80℃; for 3h;	93%

: 58-56-0
pyridoxal hydrochloride

: 121-57-3
4-aminobenzene sulfonic acid

: 1122445-21-9
C14H14N2O5S

Conditions

Conditions	Yield
Stage #1: pyridoxal hydrochloride With RuCl2(PPh3)2(BAOBEA); dihydrogen peroxide In water at 60℃; for 0.25h; Stage #2: 4-aminobenzene sulfonic acid In water for 0.0833333h; Reflux;	98.25%

: 58-56-0
pyridoxal hydrochloride

: 77-76-9
2,2-dimethoxy-propane

: 1136-52-3
(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol

Conditions

Conditions	Yield
With toluene-4-sulfonic acid In acetone at 20℃;	98%
With toluene-4-sulfonic acid In acetone at 20℃; for 23h;	96%
With toluene-4-sulfonic acid In acetone at 20℃; for 23h;	96%
With toluene-4-sulfonic acid In acetone at 20℃; for 20h; Inert atmosphere;	86%
With toluene-4-sulfonic acid In water; acetone for 20h; Inert atmosphere;	80%

: 58-56-0
pyridoxal hydrochloride

: 108-24-7
acetic anhydride

: 10030-93-0
pyridoxine triacetate

Conditions

Conditions	Yield
With triethylamine In tert-butyl methyl ether at 50 - 65℃; for 2.5h; Industry scale; Heating / reflux;	96%
With pyridine Ambient temperature;	57%
With pyridine

: 58-56-0
pyridoxal hydrochloride

: 108-24-7
acetic anhydride

: 53580-75-9
2,4-dimethyl-5-acetoxymethylpyridin-3-ol

Conditions

Conditions	Yield
With zinc for 2h; Reflux;	95%

: cobalt(II) chloride hexahydrate

: 617-65-2
Glutamic acid

: 58-56-0
pyridoxal hydrochloride

: Co(2+)*C5HN(CH3)(O)(CH2OH)2(1-)*OOCCH2CH2(NH2)CHCOO(2-)*H(1+)*3H2O=Co{C5HN(CH3)(O)(CH2OH)2}(C5H8NO4)*3H2O

Conditions

Conditions	Yield
With lithium carbonate In water byproducts: CO2; to soln. pyridoxine/water was added equimolar amt. glutamic acid and excess Li2CO3, after evolution CO2 completed addn. equimolar soln. CoCl2/H2O, formation of pink ppt.; ppt. separated, washed (EtOH and ether) until powdery, elem. anal.;	94.4%

...Expand

: 58-56-0
pyridoxal hydrochloride

: 148-51-6
3-hydroxy-5-hydroxymethyl-2,4-dimethylpyridinium chloride

Conditions

Conditions	Yield
Stage #1: pyridoxal hydrochloride With acetic acid; zinc for 12h; Reflux; Stage #2: With hydrogenchloride In methanol at 0℃; for 2h;	94%
Stage #1: pyridoxal hydrochloride With acetic acid; zinc for 12h; Reflux; Stage #2: With hydrogenchloride In methanol; water at 0℃; for 2h;	94%
With acetic acid; zinc for 24h; Reflux;	94%
Stage #1: pyridoxal hydrochloride With acetic acid; zinc at 120℃; for 3h; Stage #2: With hydrogenchloride In methanol at 60℃; for 1h;	93%
Multi-step reaction with 2 steps 1: zinc / 72 h / Reflux 2: hydrogenchloride / water / 8 h / 50 °C View Scheme

: 58-56-0
pyridoxal hydrochloride

: 102694-13-3
4,5-bis-chloromethyl-2-methyl-pyridin-3-ol

Conditions

Conditions	Yield
With thionyl chloride In N,N-dimethyl-formamide for 0.5h; Reflux;	93%
With thionyl chloride In N,N-dimethyl-formamide for 0.5h; Inert atmosphere; Reflux;	93%

: 58-56-0
pyridoxal hydrochloride

: 77-76-9
2,2-dimethoxy-propane

A: 1136-52-3
(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol

B: 948-00-5
1,5-dihydro-3,3,8-trimethyl<1,3>dioxepino<5,6-y>pyridin-9-ol

Conditions

Conditions	Yield
With sulfuric acid In dichloromethane for 6h; Heating;	A 92% B n/a

...Expand

: 58-56-0
pyridoxal hydrochloride

A: 948-00-5
1,5-dihydro-3,3,8-trimethyl<1,3>dioxepino<5,6-y>pyridin-9-ol

B: 77-76-9
2,2-dimethoxy-propane

Conditions

Conditions	Yield
With sulfuric acid In dichloromethane for 6h; Heating; Title compound not separated from byproducts;	A n/a B 92%

: 58-56-0
pyridoxal hydrochloride

: 67-64-1
acetone

: 6953-28-2
(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride	92%
With hydrogenchloride for 2.5h;	90.9%
With hydrogenchloride at 20 - 30℃; for 6h;	85%
With hydrogenchloride HCl introduction below 10 degC, then -10 degC, overnight;	54%
With hydrogenchloride at 0℃; for 2h;	27.3 g

: 58-56-0
pyridoxal hydrochloride

: 67-64-1
acetone

: 1136-52-3
(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol

Conditions

Conditions	Yield
With thionyl chloride In chloroform at 20℃; for 6h; ketalization;	91%
With sulfuric acid at 20℃;	65%
With Dess-Martin periodane; toluene-4-sulfonic acid at 20℃; for 20h; Inert atmosphere;	63%

: 58-56-0
pyridoxal hydrochloride

: 108-94-1
cyclohexanone

: 4632-05-7
3,4'-O-cyclohexylidenepyridoxine

Conditions

Conditions	Yield
With thionyl chloride In chloroform at 20℃; ketalization;	90%
With sulfuric acid
Acidic conditions;

: 58-56-0
pyridoxal hydrochloride

: 67-64-1
acetone

: 948-00-5
1,5-dihydro-3,3,8-trimethyl<1,3>dioxepino<5,6-y>pyridin-9-ol

Conditions

Conditions	Yield
With thionyl chloride In chloroform at 0 - 20℃; for 7h; ketalization;	90%
With hydrogenchloride at 3 - 20℃;	87%
(i) HCl, (ii) aq. K2CO3; Multistep reaction;

: 58-56-0
pyridoxal hydrochloride

: 67-64-1
acetone

: 111422-99-2
chlorhydrate d'hydroxy-8 trimethyl-2,2,7 pyrido-<4,5-e>dioxa 1,3-cycloheptane

Conditions

Conditions	Yield
With hydrogenchloride at 0℃; for 1h;	88%

: 693-54-9
Decan-2-one

: 58-56-0
pyridoxal hydrochloride

: 5-(hydroxymethyl)-2,8-dimethyl-2-octyl-4H-[1,3]dioxino[4,5-c]pyridine

Conditions

Conditions	Yield
With toluene-4-sulfonic acid In toluene for 17h; Reflux; Dean-Stark;	87%

: 58-56-0
pyridoxal hydrochloride

: 613-94-5
benzoic acid hydrazide

: N'-{(3-hydroxyl-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene}benzohydrazide hydrochloride

Conditions

Conditions	Yield
Stage #1: pyridoxal hydrochloride With manganese(IV) oxide; sulfuric acid In water at 60 - 70℃; Stage #2: benzoic acid hydrazide In water for 0.166667h; Heating;	86%

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 58-56-0
pyridoxal hydrochloride

: C50H47NO7

Conditions

Conditions	Yield
In pyridine; dichloromethane at 20℃; Inert atmosphere;	85%

: 58-56-0
pyridoxal hydrochloride

: 58479-61-1
tert-butylchlorodiphenylsilane

: C40H47NO3Si2

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 0 - 20℃;	83%
With triethylamine In tetrahydrofuran for 1.5h; Cooling with ice;	67%

: 58-56-0
pyridoxal hydrochloride

: 100-39-0
benzyl bromide

: 7442-21-9
[5-(benzyloxy)-4-(hydroxymethyl)-6-methylpyridin-3-yl]methanol

Conditions

Conditions	Yield
Stage #1: pyridoxal hydrochloride With potassium carbonate In acetonitrile at 90℃; for 1h; Stage #2: benzyl bromide In acetonitrile for 3h; Reflux;	83%

Pyridoxine hydrochloride Chemical Properties

IUPAC Name: 4,5-Bis(hydroxymethyl)-2-methylpyridin-3-ol hydrochloride
Molecular Formula: C₈H₁₂ClNO₃
Molecular Weight: 205.64 g/mol
SMILES: c1(c(cnc(c1O)C)CO)CO.Cl
InChI: InChI=1/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H
EINECS: 200-386-2
Classification Code: Drug / Therapeutic Agent; Human Data; Mutation data; Reproductive Effect; Vitamin [enzyme co-factor]
Product Categories: Biochemistry; Pyridinium Compounds; Vitamins; Nutritional Supplements; Vitamins and derivatives; Aromatics; Heterocycles; Vitamin Ingredients
Flash Point: 251.3 °C
Enthalpy of Vaporization: 79.91 kJ/mol
Boiling Point: 491.9 °C at 760 mmHg
Melting Point: 214-215 °C(lit.)
storage temperature: 2-8 °C
solubility: H₂O: 0.1 g/mL at 20 °C, clear, colorless
Sensitive: Light Sensitive
Stability: Stable. Protect from air and light.
Vapour Pressure of Pyridoxine hydrochloride (CAS NO.58-56-0): 1.71E-10 mmHg at 25 °C

Pyridoxine hydrochloride Uses

Pyridoxine hydrochloride (CAS NO.58-56-0) is widely used in pharmaceutical ,food and feed additives and also could be used in the cosmetics .

Pyridoxine hydrochloride Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LD50	intramuscular	500mg/kg (500mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 922, 1961.
cat	LD50	intravenous	560mg/kg (560mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 922, 1961.
cat	LD50	oral	1gm/kg (1000mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 922, 1961.
dog	LD50	oral	> 500mg/kg (500mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 922, 1961.
mouse	LD50	intravenous	660mg/kg (660mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 922, 1961.
mouse	LD50	oral	5500mg/kg (5500mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 922, 1961.
mouse	LD50	subcutaneous	2450mg/kg (2450mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 922, 1961.
pigeon	LD50	intravenous	145mg/kg (145mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 922, 1961.
rabbit	LD50	intravenous	464mg/kg (464mg/kg)	PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 922, 1961.
rat	LD50	intravenous	530mg/kg (530mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT	Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 922, 1961.
rat	LD50	oral	4gm/kg (4000mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT	Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 922, 1961.
rat	LD50	subcutaneous	3gm/kg (3000mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT	Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 922, 1961.

Pyridoxine hydrochloride Consensus Reports

Reported in EPA TSCA Inventory.

Pyridoxine hydrochloride Safety Profile

Hazard Codes: Irritant Xi
Risk Statements: 36/37/38
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 26-37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39: Wear suitable gloves and eye/face protection.
WGK Germany: 2
RTECS of Pyridoxine hydrochloride (CAS NO.58-56-0): UV1350000

Pyridoxine hydrochloride Specification

Pyridoxine hydrochloride (CAS NO.58-56-0), its Synonyms are 3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-, hydrochloride ; 5-Hydroxy-6-methyl-3,4-pyridinedimethanol hydrochloride ; Vitamin B6 hydrochloride ; 2-Methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine hydrochloride ; 3-Hydroxy-4,5-dihydroxymethyl-2-methylpyridine hydrochloride ; 3-Hydroxy-4,5-dimethylol-alpha-picoline hydrochloride ; 4,5-Bis(hydroxymethyl)-2-methylpyridin-3-ol hydrochloride ; Aderomine hydrochloride ; 3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-, hydrochloride (1:1) . It is crystalline.

Product Name

Pyridoxine hydrochloride

Synthetic route

Pyridoxine hydrochloride Chemical Properties

Pyridoxine hydrochloride Uses

Pyridoxine hydrochloride Toxicity Data With Reference

Pyridoxine hydrochloride Consensus Reports

Pyridoxine hydrochloride Safety Profile

Pyridoxine hydrochloride Specification

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