Resveratrol supplier | CasNO.501-36-0

Name
Resveratrol
EINECS 610-504-8
CAS No. 501-36-0
Article Data128
CAS DataBase
Density 1.359 g/cm³
Solubility Soluble in water (3 mg/100mL), ethanol (50 mg/mL), DMSO (16 mg/mL), DMF (~65 mg/mL), PBS (pH 7.2) (~100µg/mL), methanol, and acetone (50 mg/mL).
Melting Point 253-255 °C
Formula C₁₄H₁₂O₃
Boiling Point 449.1 °C at 760 mmHg
Molecular Weight 228.247
Flash Point 222.3 °C
Transport Information
Appearance Off-White to Tan Powder
Safety 26-39-37/39
Risk Codes 37/38-41-36/38
Molecular Structure
Hazard Symbols Xi
Synonyms 1,3-Benzenediol,5-[(1E)-2-(4-hydroxyphenyl)ethenyl]-;1,3-Benzenediol,5-[2-(4-hydroxyphenyl)ethenyl]-, (E)-;(E)-2-(3,5-Dihydroxyphenyl)-1-(4-hydroxyphenyl)ethene;(E)-3,4',5-Trihydroxystilbene;(E)-5-(p-Hydroxystyryl)resorcinol;3,4',5-Trihydroxy-trans-stilbene;5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol;CA 1201;Resvida;trans-Resveratrol;Natural Resveratrol Polygonum Cuspidatum Extract;100% Natural Resveratrol Polygonum Cuspidatum Extract;
PSA 60.69000
LogP 2.97380

Synthetic route

: 22255-22-7
3,5,4'-trimethoxy-trans-stilbene

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions

Conditions	Yield
With boron tribromide In dichloromethane at 0 - 30℃;	100%
With boron tribromide In dichloromethane at 0 - 20℃;	99%
With aluminum (III) chloride; sodium sulfate; triethylamine In chlorobenzene at 0 - 115℃; for 6.5h; Inert atmosphere;	98%

: 89946-06-5
(E)-1-(4-(benzyloxy)phenyl)-2-(3,5-bis(benzyloxy)phenyl)-ethene

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions

Conditions	Yield
Stage #1: (E)-1-(4-(benzyloxy)phenyl)-2-(3,5-bis(benzyloxy)phenyl)-ethene With aluminum (III) chloride; triethylamine In chlorobenzene at 0 - 80℃; for 10h; Stage #2: With water In chlorobenzene at 0℃; for 2h; Product distribution / selectivity;	100%
With aluminum (III) chloride; N,N-dimethyl-aniline at 40 - 50℃;	90%
With hydrogen In dichloromethane at 20℃; under 3750.38 Torr; for 5h;	87%

: 710969-83-8
(E)-3,5,4'-tri(benzoyloxy)styrene

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions

Conditions	Yield
With sodium methylate In tetrahydrofuran; methanol at 50℃; for 5h;	98%

: 1217011-33-0
(E)-4-(3,5-bis(methoxymethoxy)styryl)phenol

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions

Conditions	Yield
With hydrogenchloride In methanol; water at 20 - 65℃; for 3h; Inert atmosphere;	97%

: 26153-38-8
3,5-dihydroxybenzaldehyde

: 68997-88-6
dimethyl (4-hydroxybenzyl)phosphonate

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions

Conditions	Yield
With RS004 catalyst In ethanol at 20℃; for 6h; Wittig-Horner Reaction;	97%

: 411233-11-9
4'-Acetylresveratrol

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions

Conditions	Yield
With sodium hydroxide In tetrahydrofuran for 2h; Heating;	95%

: 22255-22-7, 94608-23-8, 63844-75-7
3,5,4'-trimethoxystilbene

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions

Conditions	Yield
Stage #1: 3,5,4'-trimethoxystilbene With boron tribromide In toluene at 0 - 20℃; for 2.03333h; Stage #2: With water; sodium hydrogencarbonate In toluene at 0℃; for 0.333333h;	92%
With aluminum (III) chloride; triethylamine In chlorobenzene at 60 - 70℃; for 0.5h; Inert atmosphere;	90%
Multi-step reaction with 2 steps 1: BBr3 2: diphenyl disulphide / tetrahydrofuran / Heating View Scheme
With pyridine hydrochloride at 190 - 195℃; for 4h;
Stage #1: 3,5,4'-trimethoxystilbene With iodine In hexane for 48h; Reflux; Stage #2: With boron tribromide In dichloromethane at 0 - 20℃; for 5h;

: 1399502-89-6
(E)-2,4,6-tribromo-3,5,4'-trihydroxystilbene

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions

Conditions	Yield
With sodium sulfite In water at 60℃; for 6h; Green chemistry;	90%

: 42206-94-0
triacetyl-trans-resveratrol

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions

Conditions	Yield
With sodium hydroxide In tetrahydrofuran	88%
Stage #1: triacetyl-trans-resveratrol With potassium hydroxide In methanol for 1h; Inert atmosphere; Reflux; Stage #2: With hydrogenchloride In methanol; water pH=2; Inert atmosphere;	79%
With sodium methylate In tetrahydrofuran; methanol
With potassium hydroxide In methanol; ethyl acetate

: 587870-67-5
(E)-1-(3,5-di-isopropoxyphenyl)-2-(4-isopropoxyphenyl)ethene

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions

Conditions	Yield
With boron trichloride In dichloromethane at -78 - -10℃;	85%

: C15H12O5(C2H2O)3

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions

Conditions	Yield
With 1-methyl-1H-imidazole; sodium hydrogencarbonate for 0.333333h; Heating; microwave irradiation;	84%

: 94608-23-8
(Z)-1-(3,5-dimethoxyphenyl)-2-(4-methoxyphenyl)ethene

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions

Conditions	Yield
With aluminium(III) iodide In acetonitrile at 82℃; for 3h;	83.8%
With aluminium(III) iodide In acetonitrile at 82℃; for 3h;	73%

: 22139-77-1
pinosylvin

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions

Conditions	Yield
With L234Q/I238V/G239A In dimethyl sulfoxide at 20℃; for 20h; Reagent/catalyst; Enzymatic reaction; regioselective reaction;	83%
With unspecific peroxygenase from Marasmius rotula DSM-25031; dihydrogen peroxide; ascorbic acid In aq. phosphate buffer; acetone at 30℃; for 0.5h; pH=7; Enzymatic reaction; regioselective reaction;

: 906463-95-4
C15H12O5

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions

Conditions	Yield
With copper(l) iodide; 1,10-Phenanthroline at 180 - 190℃; Microwave irradiation; Inert atmosphere; Green chemistry;	82%

: 5-[(1E)-2-(phenylbenzyloxy)vinyl]-1,3-cyclohexanedione

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions

Conditions	Yield
With 5%-palladium/activated carbon; hydrogen In acetonitrile under 2280.15 Torr; for 48h;	80%

: 676596-85-3
(E)-1-(3,5-bis-{[tert-butyl(dimethyl)silyl]oxy}phenyl)-2-(4-{[tert-butyl(dimethyl)silyl]oxy}phenyl)ethene

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions

Conditions	Yield
With hydrogenchloride In ethanol at 20℃; for 26h;	79%
With hydrogenchloride In methanol at 20℃; for 36h;

: 1026420-83-6
1-(1-bromoethyl)-3,5-diacetoxybenzene

: 1927-95-3
4-bromophenyl acetate

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions

Conditions	Yield
Stage #1: 1-(1-bromoethyl)-3,5-diacetoxybenzene With lithium carbonate In ISOPROPYLAMIDE at 120℃; for 2h; Inert atmosphere; Stage #2: 4-bromophenyl acetate With potassium phosphate; palladium oximate In ISOPROPYLAMIDE at 130℃; for 19.75h; Inert atmosphere; Stage #3: With water; potassium carbonate at 110℃; for 2.5h; Product distribution / selectivity;	77%

: 123-08-0
4-hydroxy-benzaldehyde

: (3,5-dihydroxybenzyl)triphenylphosphonium bromide

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions

Conditions	Yield
With potassium tert-butylate In tetrahydrofuran at 80℃;	75%

: 190371-53-0
(E)-1-[4-(hexyloxy)phenyl]-2-(3,5-dimethoxyphenyl)ethene

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions

Conditions	Yield
With boron tribromide In dichloromethane at 0 - 20℃; for 4h;	70%

: (E)-2-(4'-hydroxyphenyl)-3-(3',5'-dihydroxyphenyl)acrylic acid

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions

Conditions	Yield
With quinoline; copper at 200℃; for 3h; Inert atmosphere; diastereoselective reaction;	60.8%
With quinoline; copper

: 4670-09-1
2-(3,5-dihydroxyphenyl)acetic acid

: 123-08-0
4-hydroxy-benzaldehyde

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions

Conditions	Yield
With piperidine; 1-methyl-1H-imidazole In various solvent(s) at 160℃; for 0.166667h; microwave irradiation;	51%

: 64339-43-1
5-iodoresorcinol

: 2628-17-3
4-Vinylphenol

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions

Conditions	Yield
With triethanolamine; palladium diacetate at 100℃; for 24h; Mizoroki-Heck reaction; Inert atmosphere;	41.4%
With triethanolamine; palladium diacetate at 100℃; for 24h; Mizoroki-Heck reaction; Inert atmosphere; stereoselective reaction;	41.4%
With triethanolamine; palladium diacetate at 100℃; for 24h; Heck Reaction; Inert atmosphere;

: 65728-21-4, 33626-08-3
5-[(E)-2-(4-methoxyphenyl)vinyl]benzene-1,3-diol

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions

Conditions	Yield
With pyridine hydrochloride
With boron trichloride; tetra-(n-butyl)ammonium iodide In dichloromethane at 0℃; for 7h; Inert atmosphere;	81 mg

: 27208-80-6, 65914-17-2, 148766-36-3
polydatin

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions

Conditions	Yield
In water at 21℃; for 14h; β-glucosidase, pH 6;
With proteolytic enzymes at 0 - 15℃; Enzymatic reaction;
With recombinant β-glucosidase from Thermotoga maritima In aq. phosphate buffer; dimethyl sulfoxide at 90℃; pH=5.8; Kinetics; Enzymatic reaction;
With glucosidases from Bacillus safensis CGMCC 13129 at 37℃; for 8h; pH=7; Temperature; pH-value; Enzymatic reaction;

: 501-36-0, 61434-67-1, 133294-37-8
resveratrol

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions

Conditions	Yield
With diphenyldisulfane In tetrahydrofuran Isomerization; Heating;

2-<4-hydroxy-phenyl>-3-<3,5-dihydroxy-phenyl>-acrylic acid: 2-<4-hydroxy-phenyl>-3-<3,5-dihydroxy-phenyl>-acrylic acid

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions

Conditions	Yield
With quinoline; copper at 220℃;

3,5,4'-triacetoxy-trans(?)-stilbene: 3,5,4'-triacetoxy-trans(?)-stilbene

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

Conditions

Conditions	Yield
With sodium hydroxide
With sodium hydroxide

: 587870-59-5
cis-3,4',5-triisopropoxystilbene

A: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

B: 61434-67-1
cis-resveratrol

Conditions

Conditions	Yield
With boron trichloride In dichloromethane at -78 - 0℃; for 2.25h;

: 2628-17-3
4-Vinylphenol

: 113231-14-4
1,3-dihydroxy-5-vinylbenzene

A: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

B: 33626-09-4
(E)-3,3',5,5'-tetrahydroxystilbene

Conditions

Conditions	Yield
Grubbs catalyst first generation In tetrahydrofuran for 1h; Heating;	A 95 % Chromat. B 5 % Chromat.

...Expand

: 186581-53-3, 908094-01-9
diazomethane

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

: 22255-22-7
3,5,4'-trimethoxy-trans-stilbene

Conditions

Conditions	Yield
In methanol; diethyl ether at 10℃; for 24h;	100%

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

: 108-24-7
acetic anhydride

: 42206-94-0
triacetyl-trans-resveratrol

Conditions

Conditions	Yield
With pyridine at 20 - 80℃;	100%
With sodium hydroxide In dichloromethane; water at 20℃; Concentration; Reagent/catalyst; Solvent; Temperature; Large scale;	95%
With triethylamine In dichloromethane at 20℃;	92%

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

: 74-88-4
methyl iodide

: 22255-22-7
3,5,4'-trimethoxy-trans-stilbene

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 20℃; for 2h;	100%
Stage #1: (E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol With potassium carbonate In acetone at 25℃; for 0.0833333h; Inert atmosphere; Stage #2: methyl iodide In acetone at 25℃; for 12h; Inert atmosphere;	93%
Stage #1: (E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol With potassium carbonate In acetone at 25℃; for 0.0833333h; Inert atmosphere; Stage #2: methyl iodide In acetone at 25℃; for 12h; Inert atmosphere;	93%

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

: 3068-32-4
1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside

: resveratrol galactoside conjugate peracetate

Conditions

Conditions	Yield
With 2,4,6-trimethyl-pyridine; silver carbonate; molecular sieve, 3 A In dichloromethane; acetonitrile at 25℃; for 72h; Under anhydrous N2;	100%

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

: (E)-3,5,4'-trihydroxy-2,4,6-trideuterostilbene

Conditions

Conditions	Yield
With perchloric acid; deuteromethanol at 20℃; for 4h; Reagent/catalyst; Inert atmosphere;	100%
With water-d2 In acetonitrile at 90℃; for 24h; Darkness;

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

: 10083-24-6
trans-piceatannol

Conditions

Conditions	Yield
With streptomyces avermilitis tyrosinase; benzene-1,2-diol In aq. buffer for 3h; pH=8; Reagent/catalyst; Enzymatic reaction;	100%
With ascorbic acid In aq. phosphate buffer; dimethyl sulfoxide at 30℃; pH=6.0;	100%
With benzene-1,2-diol In aq. phosphate buffer at 30℃; pH=7.5; Microbiological reaction; regioselective reaction;

: 358-23-6
trifluoromethylsulfonic anhydride

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

: C17H9F9O9S3

Conditions

Conditions	Yield
With pyridine In dichloromethane at 0 - 20℃;	100%

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

: 13939-69-0
piperidine carbamoyl chloride

: 1416356-15-4
(E)-3,5,4'-tri[(piperidine-N-carbonyl)oxy]stilbene

Conditions

Conditions	Yield
With dmap; potassium carbonate In acetone Reflux; Inert atmosphere;	99.3%

: 31643-49-9
4-Nitrophthalonitrile

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

: C38H18N6O3

Conditions

Conditions	Yield
With potassium carbonate In dimethyl sulfoxide at 80℃; Inert atmosphere;	99%

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

: 112-67-4
n-hexadecanoyl chloride

: 411233-17-5
resveratrol tripalmitate

Conditions

Conditions	Yield
With pyridine at 20℃; for 12h;	99%

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

: 592-34-7
carbonochloridic acid, butyl ester

: resveratrol tris(butyl carbonate)

Conditions

Conditions	Yield
With pyridine In toluene at 20℃;	99%

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

: 58436-28-5
dihydroresveratrol

Conditions

Conditions	Yield
With hydrogen; palladium on activated charcoal	98%
With 5%-palladium/activated carbon; hydrogen In methanol at 20℃; under 2250.23 Torr; for 3h;	97.82%
With palladium 10% on activated carbon; hydrogen In ethanol at 20℃; under 3800.26 Torr; for 8h;	95%

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

: 111-64-8
n-octanoic acid chloride

: [4-[(E)-2-[3,5-di(octanoyloxy)phenyl]vinyl]phenyl] octanoate

Conditions

Conditions	Yield
Stage #1: (E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol With dmap; triethylamine In dichloromethane at 10℃; Stage #2: n-octanoic acid chloride In dichloromethane at 10℃; for 1h;	96.7%
With potassium carbonate In acetonitrile at 25℃; for 20h;	20%
With pyridine
With pyridine at 20℃;
With potassium carbonate In acetonitrile at 25℃; for 20h;

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

: 68-12-2, 33513-42-7
N,N-dimethyl-formamide

: (E)-2,4-dihydroxyl-6-(4′-hydroxylstyryl)benzaldehyde

Conditions

Conditions	Yield
Stage #1: (E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol; N,N-dimethyl-formamide With trichlorophosphate In acetonitrile at 20℃; for 2.5h; Vilsmeier reaction; Cooling with ice; Stage #2: With water In acetonitrile at 50℃; for 3h; Vilsmeier reaction;	96%
With trichlorophosphate In N,N-dimethyl-formamide; acetonitrile at 20℃; for 2.5h; Vilsmeier Reaction; Cooling with ice;	96%
With trichlorophosphate at 20℃; for 3h; Cooling with ice;	95%

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

: 108-24-7
acetic anhydride

: acetyl-trans-resveratrol

Conditions

Conditions	Yield
With triethylamine In ethyl acetate at 0 - 70℃; for 2h;	96%

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

: 100-39-0
benzyl bromide

: 89946-06-5
(E)-1-(4-(benzyloxy)phenyl)-2-(3,5-bis(benzyloxy)phenyl)-ethene

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 16h;	95%

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

: 298-14-6
potassium hydrogencarbonate

: (E)-2,6-dihydroxy-4-(4-hydroxystyryl)benzoic acid

Conditions

Conditions	Yield
With Lyophilized E. coli whole cells overexpressed Rhizobium sp. 2,6-dihydroxybenzoic acid decarboxylase In methanol; aq. phosphate buffer at 30℃; for 24h; pH=8.5; Catalytic behavior; Reagent/catalyst; Solvent; Enzymatic reaction; regioselective reaction;	95%

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

: 760-67-8
2-ethylhexanoic acid chloride

: (E)-5-(4-(2-ethylhexanoyloxy)styryl)-1,3-phenylene bis(2-ethylhexanoate)

Conditions

Conditions	Yield
Stage #1: (E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol With dmap; triethylamine In dichloromethane at 10℃; Stage #2: 2-ethylhexanoic acid chloride In dichloromethane at 10℃; for 1h;	94.8%

: 3350-78-5
3,3-Dimethylacryloyl chloride

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

: (E)-5-(4-(3-methylbut-2-enoyloxy)styryl)-1,3-phenylene bis(3-methylbut-2-enoate)

Conditions

Conditions	Yield
Stage #1: (E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol With dmap; triethylamine In dichloromethane at 10℃; Stage #2: 3,3-Dimethylacryloyl chloride In dichloromethane at 10℃; for 1h;	92.5%

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

: 62218-12-6
trans-δ-viniferin

Conditions

Conditions	Yield
With dihydrogen peroxide In water; acetone at 40℃; for 1h; Reagent/catalyst;	92%
Stage #1: (E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol With horseradish peroxidase In acetone at 40℃; for 0.5h; pH=8; Stage #2: With dihydrogen peroxide In acetone at 40℃; for 1h; pH=8;	89%
With silver(I) acetate In methanol at 50℃; for 1h;	86%

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

: 61434-67-1
cis-resveratrol

Conditions

Conditions	Yield
for 1.66667h; Irradiation; isomerization;	90.6%
Inert atmosphere; UV-irradiation;	81%
In ethanol Irradiation;

: 22884-10-2
imidazol-1-ylacetic acid

: 501-36-0
(E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol

: (E)-3-hydroxy-5-(4-hydroxystyryl)phenyl 2-(1H-imidazol-1-yl)acetate

Conditions

Conditions	Yield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane; N,N-dimethyl-formamide at 60℃; for 3h;	90%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane; N,N-dimethyl-formamide at 60℃; for 3h;	90%

Resveratrol Specification

The Resveratrol, with the CAS registry number 501-36-0,is also known as 3,4',5-Trihydroxy-trans-stilbene; 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol. It belongs to the product categories of Intermediates & Fine Chemicals;Pharmaceuticals;Caspases/Apoptosis;Health supplements.Its EINECS number is 501-36-0. This chemical's molecular formula is C₁₄H₁₂O₃ and molecular weight is 228.24. What's more,Its systematic name is 1,3-Benzenediol,5-(2-(4-hydroxyphenyl)ethenyl)-,(E)-.It is Off-White to Tan Powder.It is a phytoalexin derived from grapes and other food products with antioxidant and potential chemopreventive activities. Resveratrol induces phase II drug-metabolizing enzymes (anti-initiation activity); mediates anti-inflammatory effects and inhibits cyclooxygenase and hydroperoxidase functions (anti-promotion activity); and induces promyelocytic leukemia cell differentiation (anti-progression activity), thereby exhibiting activities in three major steps of carcinogenesis.

Physical properties about Resveratrol are:
(1)ACD/LogP: 3.139; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 3.14; (4)ACD/LogD (pH 7.4): 3.13; (5)ACD/BCF (pH 5.5): 143.19; (6)ACD/BCF (pH 7.4): 140.74; (7)ACD/KOC (pH 5.5): 1215.59; (8)ACD/KOC (pH 7.4): 1194.74; (9)#H bond acceptors: 3; (10)#H bond donors: 3; (11)#Freely Rotating Bonds: 5; (12)Index of Refraction: 1.763; (13)Molar Refractivity: 69.291 cm3; (14)Molar Volume: 167.93 cm3; (15)Surface Tension: 70.7279968261719 dyne/cm; (16)Density: 1.359 g/cm3; (17)Flash Point: 222.313 °C; (18)Enthalpy of Vaporization: 73.496 kJ/mol; (19)Boiling Point: 449.115 °C at 760 mmHg; (20)Vapour Pressure: 0 mmHg at 25°C;

You can still convert the following datas into molecular structure:
(1)SMILES:Oc2cc(\C=C\c1ccc(O)cc1)cc(O)c2;
(2)Std. InChI:InChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+;
(3)Std. InChIKey:LUKBXSAWLPMMSZ-OWOJBTEDSA-N;

Safety Information of Resveratrol:
The Resveratrol is risk of serious damage to eyes .It is irritating to eyes ,respiratory system and skin.When you use it ,wear suitable protective clothing, gloves and eye/face protection.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

Product Name

Resveratrol

Synthetic route

Resveratrol Specification

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