chlorobenzene
sodium p-chlorobenzenesulphinate
Conditions | Yield |
---|---|
Stage #1: chlorobenzene With aluminum (III) chloride; 1,4-diazabicyclo [2.2.2] octane-1,4-diium-1,4-disulfinate In 1,2-dichloro-ethane at 25℃; for 2h; Stage #2: With sodium hydrogencarbonate In water; 1,2-dichloro-ethane at 25℃; | 98% |
With 1,4-diaza-bicyclo[2.2.2]octane; aluminum (III) chloride; sodium hydrogencarbonate In dichloromethane; water at 25 - 35℃; | 88% |
Multi-step reaction with 2 steps 1: chlorosulfonic acid / 1 h / 20 °C 2: sodium sulfite / water / 1 h / 80 - 90 °C View Scheme |
4-chlorobenzenesulfonyl chloride
sodium p-chlorobenzenesulphinate
Conditions | Yield |
---|---|
With sodium hydrogencarbonate; sodium sulfite In water at 80℃; for 4h; | 96% |
With sodium carbonate; sodium sulfite In water at 50℃; for 2h; | 94% |
With sodium hydrogencarbonate; sodium sulfite In water for 3h; Reflux; | 75% |
p-Chlorothiophenol
sodium p-chlorobenzenesulphinate
Conditions | Yield |
---|---|
Stage #1: p-Chlorothiophenol With sodium acetate; acrylic acid methyl ester In tetrahydrofuran; water at 20℃; Stage #2: With 3-chloro-benzenecarboperoxoic acid In dichloromethane at 20℃; Stage #3: With sodium hydroxide In tetrahydrofuran; methanol at 0℃; Inert atmosphere; | 91% |
phenyl 4-chlorobenzenethiosulfonate
acetylacetone
A
3-(phenylthio)pentane-2,4-dione
B
sodium p-chlorobenzenesulphinate
Conditions | Yield |
---|---|
With sodium ethanolate In ethanol at 50℃; for 2h; | A 61.7% B 67.9% |
phenyl 4-chlorobenzenethiosulfonate
A
sodium p-chlorobenzenesulphinate
B
diphenyldisulfane
Conditions | Yield |
---|---|
With sodium ethanolate In ethanol at 20℃; for 1h; | A 67.6% B 65.5% |
A
sodium p-chlorobenzenesulphinate
B
sodium 4-chlorobenzenesulfonate
C
rifamycin S
Conditions | Yield |
---|---|
In ethyl acetate at 70℃; for 4h; Product distribution; | A n/a B n/a C 49% |
sodium p-chlorothiophenolate
sodium p-chlorobenzenesulphinate
Conditions | Yield |
---|---|
With oxygen |
Toluene-4-sulfonic acid 4-chloro-benzenesulfonylmethyl ester
A
formaldehyd
B
sodium p-chlorobenzenesulphinate
C
sodium tosylate
Conditions | Yield |
---|---|
With sodium hydroxide; cetyltrimethylammonim bromide In water at 32.1℃; Rate constant; Mechanism; solvolysis in H2O-dioxane; |
4-chlorobenzenesulfonyl chloride
sodium sulfite
sodium p-chlorobenzenesulphinate
Conditions | Yield |
---|---|
In not given in alkaline media; | |
In not given in alkaline media; |
4-Chlorophenylboronic acid
sodium p-chlorobenzenesulphinate
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 20 °C 1.2: 20 °C 2.1: iron(III) chloride; sodium hydroxymethanesulfinate dihydrate / N,N-dimethyl-formamide; acetonitrile / 0.33 h / 20 °C View Scheme |
sodium p-chlorobenzenesulphinate
Conditions | Yield |
---|---|
With iron(III) chloride; sodium hydroxymethanesulfinate dihydrate In N,N-dimethyl-formamide; acetonitrile at 20℃; for 0.333333h; |
p-chlorophenylsulfinyl chloride
sodium p-chlorobenzenesulphinate
Conditions | Yield |
---|---|
With sodium hydrogencarbonate; sodium sulfite In N,N-dimethyl-formamide at 80℃; for 4h; |
(2-Bromomethylbenzyloxy)-t-butyldiphenylsilane
sodium p-chlorobenzenesulphinate
t-butyl [[2-[[(4-chlorophenyl)sulfonyl]methyl]benzyl]oxy]diphenylsilane
Conditions | Yield |
---|---|
In propan-1-ol at 90℃; for 14h; | 100% |
sodium p-chlorobenzenesulphinate
sodium 4-chlorobenzenesulfonothioate
Conditions | Yield |
---|---|
With sulfur; N-butylamine at 20℃; for 1h; Other amines; | 99% |
With 5,6,7,8,9-pentathiabenzocycloheptene In methanol; benzene for 10h; Ambient temperature; | 82% |
bis(2,2,2-trichloroethyl)azodicarboxylate
sodium p-chlorobenzenesulphinate
Conditions | Yield |
---|---|
With trifluoroacetic acid In tetrahydrofuran at 0℃; for 0.5h; | 99% |
4-(benzoyloxy)morpholine
sodium p-chlorobenzenesulphinate
4-((4-chlorophenyl)sulfonyl)morpholine
Conditions | Yield |
---|---|
Stage #1: 4-(benzoyloxy)morpholine; sodium p-chlorobenzenesulphinate In 1,2-dichloro-ethane at 30℃; for 12h; Schlenk technique; Inert atmosphere; Stage #2: With copper(ll) bromide In 1,2-dichloro-ethane for 12h; Schlenk technique; Inert atmosphere; | 99% |
1-dodecene
sodium p-chlorobenzenesulphinate
1-chloro-4-(dodecylsulfonyl)benzene
Conditions | Yield |
---|---|
With [Ir(dF(CF3)ppy)2(dtbbpy)]PF6; water; acetic acid In dichloromethane at 20℃; for 12h; Inert atmosphere; Irradiation; regioselective reaction; | 99% |
sodium p-chlorobenzenesulphinate
methyl chloroacetate
methyl 4-chlorophenylsulphinylacetate
Conditions | Yield |
---|---|
98% | |
In N,N-dimethyl-formamide at 120℃; for 3h; | 98% |
In N,N-dimethyl-formamide at 45 - 115℃; for 3h; | 98% |
indole
sodium p-chlorobenzenesulphinate
2-((4-chlorophenyl)sulfonyl)-1H-indole
Conditions | Yield |
---|---|
With tert.-butylhydroperoxide; ammonium iodide; acetic acid at 60℃; for 2h; regioselective reaction; | 98% |
With iodine In methanol at 20℃; for 2h; regioselective reaction; | 88% |
With tert.-butylhydroperoxide; iodine In acetic acid at 20 - 35℃; for 4h; regioselective reaction; | 82% |
With Oxone; potassium iodide In water at 20℃; for 1h; Green chemistry; regioselective reaction; | 66% |
4-vinylbenzyl chloride
sodium p-chlorobenzenesulphinate
(E)-4-chlorostyryl 4-chlorophenyl sulfone
Conditions | Yield |
---|---|
With iodine In water at 20℃; for 2h; Schlenk technique; Green chemistry; | 98% |
sodium p-chlorobenzenesulphinate
phenol
4-chlorobenzolsulfonsaeure-phenylester
Conditions | Yield |
---|---|
In water; acetonitrile at 20℃; for 2h; Electrochemical reaction; | 98% |
indole
sodium p-chlorobenzenesulphinate
3-((4-chlorophenyl)thio)-1H-indole
Conditions | Yield |
---|---|
With iodine; triphenylphosphine In ethanol at 80℃; for 2h; Green chemistry; | 97% |
With iodine; triphenylphosphine In water Reflux; Inert atmosphere; Schlenk technique; Green chemistry; | 94% |
With Diethyl phosphonate; iodine; dimethyl sulfoxide at 100℃; for 15h; Inert atmosphere; Sealed tube; regioselective reaction; | 93% |
2-methyl-1H-indole
sodium p-chlorobenzenesulphinate
Conditions | Yield |
---|---|
With iodine; triphenylphosphine In water Reflux; Inert atmosphere; Schlenk technique; Green chemistry; | 97% |
With dipotassium peroxodisulfate In water; acetonitrile at 100℃; for 24h; Inert atmosphere; Green chemistry; | 88% |
3-cyclopropylidene-1,2-diphenyl-3-prop-2-en-1-one
sodium p-chlorobenzenesulphinate
Conditions | Yield |
---|---|
With acetic acid In methanol at 20℃; for 0.166667h; | 97% |
sodium p-chlorobenzenesulphinate
Conditions | Yield |
---|---|
With chloro-trimethyl-silane; tin(II) bromide In nitromethane at -15℃; for 3h; Inert atmosphere; diastereoselective reaction; | 97% |
sodium p-chlorobenzenesulphinate
3-(bromomethyl)benzonitrile
Conditions | Yield |
---|---|
In 1,2-dimethoxyethane at 70℃; for 72h; | 96% |
1,4-epoxy-1,4-dihydronaphthalene
sodium p-chlorobenzenesulphinate
Conditions | Yield |
---|---|
With palladium diacetate; tricyclohexylphosphine In water; 1,2-dichloro-ethane at 65℃; for 2h; | 96% |
sodium p-chlorobenzenesulphinate
4-methoxy-N-(8-quinolinyl)benzamide
Conditions | Yield |
---|---|
With manganese(III) triacetate dihydrate; copper dichloride at 25℃; for 1.5h; regioselective reaction; | 96% |
2-methoxy-4-benzoylamino-5-methyl-aniline
sodium p-chlorobenzenesulphinate
Conditions | Yield |
---|---|
With perchloric acid In ethanol; water Electrolysis; | 96% |
sodium p-chlorobenzenesulphinate
Desyl chloride
1,2-diphenyl-1-(p-chlorophenylsulfonyl)-2-ethanone
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide for 0.5h; Heating; | 95% |
bis(4-fluorophenyl)disulfide
sodium p-chlorobenzenesulphinate
(S)-p-Fluorophenyl p-chlorobenzenethiosulfonate
Conditions | Yield |
---|---|
With iodine at 40℃; for 5h; | 95% |
With N-Bromosuccinimide In acetonitrile at 25℃; for 15h; | 84% |
3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
sodium p-chlorobenzenesulphinate
8-(4-chlorophenyl)-1,3,7-trimethyl-1H-purine-2,6(3H,7H)-dione
Conditions | Yield |
---|---|
With bis(benzonitrile)palladium(II) dichloride; copper diacetate In 1,4-dioxane; dimethyl sulfoxide at 20 - 110℃; for 24.08h; Inert atmosphere; | 95% |
dibenzyl disulphide
sodium p-chlorobenzenesulphinate
Conditions | Yield |
---|---|
With N-Bromosuccinimide In acetonitrile at 25℃; for 15h; | 95% |
sodium p-chlorobenzenesulphinate
2-phenylimidazo[1,2-a]pyridine
3-((4-chlorophenyl)thio)-2-phenylimidazo[1,2-α]pyridine
Conditions | Yield |
---|---|
With iodine; triphenylphosphine In dichloromethane at 100℃; for 12h; Sealed tube; | 95% |
With iodine; triphenylphosphine In N,N-dimethyl-formamide at 80℃; for 12h; | 93% |
With ammonium iodide In N,N-dimethyl-formamide at 135℃; for 20h; Sealed tube; regioselective reaction; | 65% |
2-phenylimidazo[2,1-b]benzothiazole
sodium p-chlorobenzenesulphinate
Conditions | Yield |
---|---|
With iodine; triphenylphosphine In N,N-dimethyl-formamide at 80℃; for 12h; | 95% |
styrene
sodium p-chlorobenzenesulphinate
(E)-1-chloro-4-(styrylsulfonyl)benzene
Conditions | Yield |
---|---|
With iodine In water at 20℃; for 2h; Schlenk technique; Green chemistry; | 95% |
With tetrabutylammonium tetrafluoroborate; acetic acid; potassium iodide In dimethyl sulfoxide at 50℃; for 10h; Inert atmosphere; Electrochemical reaction; | 73% |
With dipotassium peroxodisulfate; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; silver nitrate In toluene at 100℃; for 10h; Schlenk technique; stereoselective reaction; | 71% |
sodium p-chlorobenzenesulphinate
4-chloro-N-(quinolin-8-yl)benzamide
Conditions | Yield |
---|---|
With manganese(III) triacetate dihydrate; copper dichloride at 25℃; for 1.5h; regioselective reaction; | 95% |
N-quinolin-8-yl-benzamide
sodium p-chlorobenzenesulphinate
Conditions | Yield |
---|---|
With manganese(III) triacetate dihydrate; copper dichloride at 25℃; for 1.5h; regioselective reaction; | 95% |
Conditions | Yield |
---|---|
With iron(III) chloride; dipotassium peroxodisulfate; sodium dodecyl-sulfate at 110℃; for 14h; | 95% |
With iron(III) chloride; dipotassium peroxodisulfate; sodium dodecyl-sulfate at 110℃; for 14h; Green chemistry; | 95% |
sodium p-chlorobenzenesulphinate
2-bromoindanone
Conditions | Yield |
---|---|
With chloro[(1S,2S)-N-(p-toluenesulfonyl)-1,2-diphenylethylenediamine]-(mesitylene) ruthenium (II); sodium formate In water; isopropyl alcohol at 60℃; for 5h; stereoselective reaction; | 95% |
IUPAC Name: Sodium 4-chlorobenzenesulfinate
Synonyms of Sodium 4-chlorobenzene sulfinate (CAS NO.14752-66-0) : Benzenesulfinic acid, 4-chloro-, sodium salt ; p-Chlorobenzenesulfinic acid, sodium salt ; Sodium 4-chlorobenzenesulfinate hydrate ; Sodium p-chlorobenzenesulphinate
CAS NO:14752-66-0
Molecular Formula: C6H4ClNaO2S
Molecular Weight:198.6
Molecular Structure:
EINECS: 238-811-9
H bond acceptors: 2
H bond donors: 1
Freely Rotating Bonds: 1
Polar Surface Area: 56.51 Å2
Flash Point: 173.9 °C
Enthalpy of Vaporization: 64.36 kJ/mol
Boiling Point: 363.9 °C at 760 mmHg
Vapour Pressure: 6.22E-06 mmHg at 25°C
Melting Point: 300 °C
Appearance: white crystalline powder
SMILES: [Na+].O=S([O-])c1ccc(Cl)cc1
InChI: InChI=1/C6H5ClO2S.Na/c7-5-1-3-6(4-2-5)10(8)9;/h1-4H,(H,8,9);/q;+1/p-1
InChIKey: JFXAUUFCZJYLJF-REWHXWOFAO
Std. InChI: InChI=1S/C6H5ClO2S.Na/c7-5-1-3-6(4-2-5)10(8)9;/h1-4H,(H,8,9);/q;+1/p-1
Std. InChIKey: JFXAUUFCZJYLJF-UHFFFAOYSA-M
Product Categories of Sodium 4-chlorobenzene sulfinate (CAS NO.14752-66-0): Industrial/Fine Chemicals
Safety Statements: 24/25-22
S22: Do not breathe dust.
S24/25: When Sodium 4-chlorobenzene sulfinate (CAS NO.14752-66-0) is used ,avoid contact with skin and eyes.
PackingGroup: III
General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam.
Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage: Store in a cool, dry place. Store in a tightly closed container.
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View