Strontium ranelate

Molecular structure of Strontium ranelate (CAS NO.135459-87-9) is:

Product Name: Strontium ranelate
CAS Registry Number: 135459-87-9
IUPAC Name: 5-[bis(carboxymethyl)amino]-3-(carboxymethyl)-4-cyanothiophene-2-carboxylic acid ; strontium
Molecular Weight: 517.5214 [g/mol]
Molecular Formula: C₁₂H₁₀N₂O₈SSr₂
H-Bond Donor: 4
H-Bond Acceptor: 10
Flash Point: 424.8 °C
Enthalpy of Vaporization: 118.88 kJ/mol
Boiling Point: 778.8 °C at 760 mmHg
Vapour Pressure: 1.57E-25 mmHg at 25°C
Product Categories: All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals

 Strontium ranelate (CAS NO.135459-87-9) is used as bone density conservation agents, which mean agents that inhibit bone resorption and/or favor bone mineralization and bone regeneration. They are used to heal bone fractures and to treat metabolic bone diseases. Here it is the only antiosteoporotic agent which both increases bone formation and reduces bone resorption, resulting in a rebalance of bone turnover in favor of bone formation. It stimulates the calcium sensing receptors and leads to the differentiation of pre-osteoblast to osteoblast which increases the bone formation. It also stimulates osteoblasts to secrete osteoprotegerin in inhibiting osteoclasts formed from pre-osteoclasts in relation to the RANKL system, which leads to the decrease of bone resorption.

 Strontium ranelate , its cas register number is 135459-87-9. It also can be called Distrontium renelate ; Osseor ; Protelos ; Protos ; Ranelic acid distrontium salt ; 3-(3-cyano-4-carboxymethyl-5-carboxy-2-thienyl)-3-azapentanedioic distrontium salt ; 3-Thiopheneacetic acid, 5-(bis(carboxymethyl .It is a crystalline solid.