TETRAETHYL LEAD supplier

Name
TETRAETHYLLEAD
EINECS 201-075-4
CAS No. 78-00-2
Article Data109
CAS DataBase
Density 1.653 g/mL at 25 ºC(lit.)
Solubility Insoluble

Hazard Symbols

Synonyms Lead,tetraethyl-; NSC 22314; TEL; Tetraethyllead; Tetraethylplumbane

PSA 0.00000

LogP 3.51480

Synthetic route

: 79110-50-2
(η5-cyclopentadienyl)W(CO)3PbEt3

A: 79123-28-7
{(η5-cyclopentadienyl)W(CO)3}2PbEt2

B: 78-00-2
tetraethyllead(IV)

Conditions

Conditions	Yield
heated in vac. to 60°C for 8 h, under nitrogen, yellow-orange liquid became solid and darker orange in colour; dissolved in CH2Cl2/hexane solution, placed upon alumina column, elutedwith hexane, then hexane/CH2Cl2 solution, concentrated and placed refrigerator;	A 58% B n/a

: 79110-53-5
(η5-cyclopentadienyl)Mo(CO)3PbEt3

A: [(η5-C5H5)Mo(CO)3]2Pb(C2H5)2

B: 78-00-2
tetraethyllead(IV)

Conditions

Conditions	Yield
Irradiation (UV/VIS); 12 h;	A 50% B n/a

: 74-96-4
ethyl bromide

: 78-00-2
tetraethyllead(IV)

Conditions

Conditions	Yield
With pyridine; lead sodium
With pyridine; tetrasodium-monoplumbide; water at 38℃;
With lead; sodium at 70℃; im geschlossenen Gefaess;

: 64-67-5
diethyl sulfate

: 78-00-2
tetraethyllead(IV)

Conditions

Conditions	Yield
With lead sodium; water; toluene; potassium iodide

: 74-85-1
ethene

: 78-00-2
tetraethyllead(IV)

Conditions

Conditions	Yield
With lead sodium; hydrogen at 100℃; under 7355.08 Torr;

: 75-00-3
chloroethane

: 78-00-2
tetraethyllead(IV)

Conditions

Conditions	Yield
With lead; lead(II) iodide at 100 - 130℃;
With lead sodium
With hydrogenchloride; lead sodium

: 811-49-4
ethyllithium

: 78-00-2
tetraethyllead(IV)

Conditions

Conditions	Yield
With lead(IV) chloride; Petroleum ether anfangs unter Kuehlung;

: 925-90-6
ethylmagnesium bromide

: 78-00-2
tetraethyllead(IV)

Conditions

Conditions	Yield
With PbS
With lead(II) chloride
With lead(II) oxide

: 557-20-0
diethylzinc

: 676-54-0
ethyl sodium

: 78-00-2
tetraethyllead(IV)

Conditions

Conditions	Yield
Electrolysis.an einer Bleianode;

: 557-20-0
diethylzinc

: 78-00-2
tetraethyllead(IV)

Conditions

Conditions	Yield
With lead(II) chloride
With lead(II) chloride

: 97-93-8
triethylaluminum

: 301-04-2
lead acetate

: 78-00-2
tetraethyllead(IV)

Conditions

Conditions	Yield
With benzene

: 97-93-8
triethylaluminum

: 78-00-2
tetraethyllead(IV)

Conditions

Conditions	Yield
With sodium fluoride Electrolysis.an Blei-Anoden;

: 2386-64-3
ethylmagnesium chloride

: 78-00-2
tetraethyllead(IV)

Conditions

Conditions	Yield
With lead(II) chloride
With diethyl ether; lead(II) chloride
With lead(II) chloride

: 2386-64-3
ethylmagnesium chloride

A: 78-00-2
tetraethyllead(IV)

B: 1067-14-7
triethyllead chloride

Conditions

Conditions	Yield
With diethyl ether; lead(II) chloride anschliessend Einleiten Luft oder Sauerstoff nach Zusatz von verd.Salzsaeure;

: 2388-00-3
hexaethyl diplumbane

: 78-00-2
tetraethyllead(IV)

Conditions

Conditions	Yield
With ethyl iodide
With silicatene

: 1067-14-7
triethyllead chloride

: 78-00-2
tetraethyllead(IV)

Conditions

Conditions	Yield
at 170℃;
With hydrogenchloride; oxygen In neat (no solvent)
With hydrogenchloride; air In neat (no solvent)
With air; HCl In neat (no solvent)
With O2; HCl In neat (no solvent)

: 97-93-8
triethylaluminum

: 75-03-6
ethyl iodide

: 78-00-2
tetraethyllead(IV)

Conditions

Conditions	Yield
With lead(II) chloride

: 75-03-6
ethyl iodide

: 78-00-2
tetraethyllead(IV)

Conditions

Conditions	Yield
With tetrasodium-monoplumbide at 72℃;
With lead sodium

: 925-90-6
ethylmagnesium bromide

: 41141-89-3
triethyllead bromide

: 141-78-6
ethyl acetate

: 78-00-2
tetraethyllead(IV)

...Expand

: 64-67-5
diethyl sulfate

: 7732-18-5
water

: 108-88-3
toluene

sodium-lead: sodium-lead

KI: KI

: 78-00-2
tetraethyllead(IV)

...Expand

: 75-00-3
chloroethane

lead-sodium-alloy: lead-sodium-alloy

: 78-00-2
tetraethyllead(IV)

Conditions

Conditions	Yield
at 35 - 70℃; Kinetics;
at 35 - 70℃;

: 75-00-3
chloroethane

lead-sodium-magnesium alloy: lead-sodium-magnesium alloy

: 78-00-2
tetraethyllead(IV)

Conditions

Conditions	Yield
at 75℃; Kinetics;
at 75℃;

: 75-00-3
chloroethane

lead-sodium-potassium-alloy: lead-sodium-potassium-alloy

: 78-00-2
tetraethyllead(IV)

Conditions

Conditions	Yield
at 30℃; Kinetics;
at 30℃;

ethyl metal-compound: ethyl metal-compound

: 78-00-2
tetraethyllead(IV)

Conditions

Conditions	Yield
With lead(II) oxide
With PbS

: 557-20-0
diethylzinc

lead chloride: lead chloride

: 78-00-2
tetraethyllead(IV)

: ethyl magnesium (1+); iodide

lead chloride: lead chloride

: 78-00-2
tetraethyllead(IV)

: 67-56-1
methanol

: 1067-14-7
triethyllead chloride

sodium-compound of nitromethane: sodium-compound of nitromethane

: 78-00-2
tetraethyllead(IV)

...Expand

: 1067-14-7
triethyllead chloride

: 71-43-2
benzene

sodium-compound of nitromethane: sodium-compound of nitromethane

: 78-00-2
tetraethyllead(IV)

...Expand

: 1117-96-0
Diazoethan

triethyl lead-chloride: triethyl lead-chloride

: 78-00-2
tetraethyllead(IV)

Conditions

Conditions	Yield
With diethyl ether; copper

: 78-00-2
tetraethyllead(IV)

: 100-52-7
benzaldehyde

: 93-54-9
1-Phenyl-1-propanol

Conditions

Conditions	Yield
With titanium tetrachloride In dichloromethane at -78 - -30℃; Product distribution; further aldehydes and tetraalkylleads; reaction with mixed tetraalkylleads; other conditions;	98%
With titanium tetrachloride In dichloromethane at -78 - -30℃;	98%
With titanium tetrachloride In dichloromethane at -78 - -30℃;	96%

: 78-00-2
tetraethyllead(IV)

: 2043-61-0
cyclohexanecarbaldehyde

: 17264-02-7
cyclohexylpropyl alcohol

Conditions

Conditions	Yield
With titanium tetrachloride In dichloromethane at -78 - -30℃;	98%

: 650-52-2
bis(trifluoromethyl)chlorophosphine

: 78-00-2
tetraethyllead(IV)

: 25196-23-0
Ethylbis-trifluormethyl-phosphin

Conditions

Conditions	Yield
110°C (24 h);	95%
110°C (24 h);	95%

: 124-13-0
Octanal

: 78-00-2
tetraethyllead(IV)

: 1565-81-7
decan-3-ol

Conditions

Conditions	Yield
With titanium tetrachloride In dichloromethane at -78 - -30℃;	94%

: 40848-81-5
N-(ethoxycarbonyl)-N-methyl-1-ethoxybenzylamine

: 78-00-2
tetraethyllead(IV)

: 127202-36-2
Methyl-(1-phenyl-propyl)-carbamic acid ethyl ester

Conditions

Conditions	Yield
With titanium tetrachloride In dichloromethane at -78 - 25℃;	88%

: 78-00-2
tetraethyllead(IV)

: 98-88-4
benzoyl chloride

: 93-55-0
1-phenyl-propan-1-one

Conditions

Conditions	Yield
tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 65℃; for 3h;	84%

: 78-00-2
tetraethyllead(IV)

: 127202-34-0
(1-Ethoxy-octyl)-methyl-carbamic acid ethyl ester

: 127202-43-1
(1-Ethyl-octyl)-methyl-carbamic acid ethyl ester

Conditions

Conditions	Yield
With titanium tetrachloride In dichloromethane at -78 - 25℃;	82%

: 20738-34-5
(p-chlorophenyl)arsonous dichloride

: 78-00-2
tetraethyllead(IV)

A: 75-00-3
chloroethane

B: 83627-00-3
(p-chlorophenyl)ethylarsinous chloride

C PbCl2: PbCl2

Conditions

Conditions	Yield
at 90 - 110℃;	A n/a B 82% C n/a

...Expand

: 81445-44-5
(S)-2-(benzyloxy)propanal

: 78-00-2
tetraethyllead(IV)

: 114418-33-6
(2S,3S)-2-benzyloxy-3-pentanol

Conditions

Conditions	Yield
With titanium tetrachloride at -78 - -60℃;	81%

: C5H5Ni(P(C2H5)3)GeCl3

: 78-00-2
tetraethyllead(IV)

: C5H5Ni(P(C2H5)3)Ge(C2H5)Cl2

Conditions

Conditions	Yield
In further solvent(s) in boiling solvent, 2 h; crystn. from C6H6/hexane, CS2/hexane or CH2Cl2;	77%
In benzene in boiling benzene, 2 h; crystn. from C6H6/hexane, CS2/hexane or CH2Cl2;	77%

: 16248-71-8
2-(dichloroamino)-2-methylpropionitrile

: 78-00-2
tetraethyllead(IV)

: 1529-35-7
triethyl lead (1+); hydroxide

Conditions

Conditions	Yield
With NaOH; HCl In tetrachloromethane byproducts: azobisbutyronitrile; stirring (25-30°C), heating (50°C, 1 h), solvent removal (vac.), addn. of aq. NaOH, stirring (pptn. of org. byproduct), neutrlization (aq. HCl); collection of ppt. (filtration);	75%

: 63294-40-6
Dichlor(o-methoxyphenyl)arsin

: 78-00-2
tetraethyllead(IV)

A: 75-00-3
chloroethane

B: 61130-93-6
ethyl-o-anisylarsine chloride

C PbCl2: PbCl2

Conditions

Conditions	Yield
at 90 - 110℃;	A n/a B 74% C n/a

...Expand

: 20738-32-3
(p-chlorophenyl)arsonous dichloride

: 78-00-2
tetraethyllead(IV)

A: 75-00-3
chloroethane

B: 83627-06-9
(o-chlorophenyl)ethylarsinous chloride

C PbCl2: PbCl2

Conditions

Conditions	Yield
at 90 - 110℃;	A n/a B 73% C n/a
at 80 - 90℃; for 1h;	A n/a B 73% C n/a

...Expand

: 78-00-2
tetraethyllead(IV)

A: 13231-90-8
diethyllead dichloride

B: 107-27-7
ethylmercury(II) chloride

Conditions

Conditions	Yield
With mercury dichloride In ethanol 4h heated at 65°C;; precipitation at cooling;;	A n/a B 72%
With HgCl2 In ethanol 4h heated at 65°C;; precipitation at cooling;;	A n/a B 72%

: 698-64-6
dichloro(4-methylphenyl)arsine

: 78-00-2
tetraethyllead(IV)

A: 75-00-3
chloroethane

B: 51525-20-3
ethyl-p-tolylarsine chloride

C PbCl2: PbCl2

Conditions

Conditions	Yield
at 90 - 110℃;	A n/a B 71% C n/a

...Expand

: 20738-33-4
(m-chlorophenyl)arsonous dichloride

: 78-00-2
tetraethyllead(IV)

A: 75-00-3
chloroethane

B: (m-chlorophenyl)ethylarsinous chloride

C PbCl2: PbCl2

Conditions

Conditions	Yield
at 90 - 110℃;	A n/a B 71% C n/a

...Expand

: 10025-91-9
antimony(III) chloride

: 78-00-2
tetraethyllead(IV)

: 68781-06-6
ethyldichlorostibine

Conditions

Conditions	Yield
In benzene refluxing in ratio of SbCl3:Pb(C2H5)4=3:1 for 8-10 h; distn.;	71%
In benzene refluxing in ratio of SbCl3:Pb(C2H5)4=3:1 for 8-10 h; distn.;	71%
in ratio of SbCl3:Pb(C2H5)4=3:1 in bulk at 100°C in N2 atmosphere for 7 h; distn.;
in ratio of SbCl3:Pb(C2H5)4=3:1 in bulk at 100°C in N2 atmosphere for 7 h; distn.;

: (ferrocenyl)dibromoborane

: 78-00-2
tetraethyllead(IV)

: 181149-05-3
diethylborylferrocene

Conditions

Conditions	Yield
In toluene byproducts: PbEt3Br; (argon); -60°C to room temp., stirring 2 h; solvent removal (vac.), dissoln. (hexane), filtration;	71%

: 51956-43-5
dichloro-(4-nitro-phenyl)-arsine

: 78-00-2
tetraethyllead(IV)

A: 75-00-3
chloroethane

B: ethyl(p-nitrophenyl)arsinous chloride

C PbCl2: PbCl2

Conditions

Conditions	Yield
at 90 - 110℃;	A n/a B 70% C n/a

...Expand

: 65452-83-7
p-anisylarsine dichloride

: 78-00-2
tetraethyllead(IV)

A: 75-00-3
chloroethane

B: 61130-95-8
chloroethyl(p-methoxyphenyl)arsine

C PbCl2: PbCl2

Conditions

Conditions	Yield
at 90 - 110℃;	A n/a B 69% C n/a

...Expand

: 57170-65-7
o-Bromphenylarsindichlorid

: 78-00-2
tetraethyllead(IV)

A: 75-00-3
chloroethane

B: 83627-07-0
C8H9AsBrCl

C PbCl2: PbCl2

Conditions

Conditions	Yield
at 90 - 110℃;	A n/a B 68% C n/a

...Expand

: 64048-88-0
(o-nitrophenyl)arsonous dichloride

: 78-00-2
tetraethyllead(IV)

A: 75-00-3
chloroethane

B: ethyl(o-nitrophenyl)arsinous chloride

C PbCl2: PbCl2

Conditions

Conditions	Yield
at 90 - 110℃;	A n/a B 68% C n/a

...Expand

: 6306-96-3
m-nitrophenylarsonous dichloride

: 78-00-2
tetraethyllead(IV)

A: 75-00-3
chloroethane

B: ethyl(m-nitrophenyl)arsinous chloride

C PbCl2: PbCl2

Conditions

Conditions	Yield
at 90 - 110℃;	A n/a B 67% C n/a

...Expand

: 73013-32-8
p-bromophenylarsine dichloride

: 78-00-2
tetraethyllead(IV)

A: 75-00-3
chloroethane

B: 83627-01-4
C8H9AsBrCl

C PbCl2: PbCl2

Conditions

Conditions	Yield
at 90 - 110℃;	A n/a B 64% C n/a

...Expand

: 58284-54-1
(3-bromo-phenyl)-dichloro-arsine

: 78-00-2
tetraethyllead(IV)

A: 75-00-3
chloroethane

B: C8H9AsBrCl

C PbCl2: PbCl2

Conditions

Conditions	Yield
at 90 - 110℃;	A n/a B 64% C n/a

...Expand

: 78-00-2
tetraethyllead(IV)

: 109832-49-7
m-biphenylyldichloroarsine

: m-biphenylyldiethylarsine

Conditions

Conditions	Yield
In xylene for 20h; Heating;	63.8%

: 696-28-6
dichlorophenylarsine

: 78-00-2
tetraethyllead(IV)

A: 75-00-3
chloroethane

B: 698-13-5
ethylphenylarsine chloride

C PbCl2: PbCl2

Conditions

Conditions	Yield
at 90 - 110℃;	A n/a B 63% C n/a

...Expand

: 697-97-2
o-tolylarsonous dichloride

: 78-00-2
tetraethyllead(IV)

A: 75-00-3
chloroethane

B: 53980-31-7
Aethyl-o-tolylarsinchlorid

C PbCl2: PbCl2

Conditions

Conditions	Yield
at 90 - 110℃;	A n/a B 62% C n/a

...Expand

: 78-00-2
tetraethyllead(IV)

: 135441-05-3
C11H19N3O3

A: 135441-06-4
N'-(Piperidine-1-carbonyl)-hydrazinecarboxylic acid tert-butyl ester

B: 135441-08-6
N'-Ethyl-N'-(piperidine-1-carbonyl)-hydrazinecarboxylic acid tert-butyl ester

Conditions

Conditions	Yield
With titanium tetrachloride In hexane; dichloromethane at -78℃; for 0.7h;	A 6% B 61%

...Expand

WOCl2 (O-2,6-C6 H3 -Br2)2: WOCl2 (O-2,6-C6 H3 -Br2)2

: 2436-90-0
(S)-(+)-dihydromyrcene

: 78-00-2
tetraethyllead(IV)

: 120-82-1
1,2,4-Trichlorobenzene

: (-)-(S)-3-methylcyclopentene

Conditions

Conditions	Yield
In chlorobenzene	61%

...Expand

TETRAETHYL LEAD Chemical Properties

IUPAC Name: tetraethylplumbane
Molecular Formula:C₈H₂₀Pb
Molecular Weight:323.4444
Appearance:colorless, viscous liquid
Melting Point:136 °C(lit.)
Boiling Point:84-85 °C15 mm Hg(lit.)
density:1.653 g/mL at 25 °C(lit.)
refractive index:n20/D 1.519(lit.)
Fp:84 °F
Solubility:slightly soluble in ethanol;
soluble in benzene, petroleum ether, toluene, gasoline
Insolubility:Water
Synonyms of TETRAETHYL LEAD(78-00-2):TEL;TETRAETHYLLEAD;
(C₂H₅)4Pb;Czteroetylek olowiu;czteroetylekolowiu;czteroetylekolowiu(polish);Lead tetraethyl;lead,tetraethyl-
Categories of TETRAETHYL LEAD(78-00-2): Organometallics;Organolead;Organometallic Reagents;Others
Merck 13,9277

TETRAETHYL LEAD Uses

TETRAETHYL LEAD(78-00-2) is used as an antiknock agent.

TETRAETHYL LEAD Production

TETRAETHYL LEAD(78-00-2) is produced by reacting chloroethane with a sodium–lead alloy.
4 NaPb + 4 CH₃CH₂Cl → (CH₃CH₂)4Pb + 4 NaCl + 3 Pb

TETRAETHYL LEAD Toxicity Data With Reference

1.	otr-ham:emb 12,500 µg/L	AETODY Advances in Modern Environmental Toxicology. 1 (1980),241.
2.	ihl-hmn TCLo:1749 g/m3/30M:NOSE,EYE,GIT	SAIGBL Sangyo Igaku. Japanese Journal of Industrial Health. 17 (1975),223.
3.	unr-man LDLo:1470 µg/kg	85DCAI Poisoning; Toxicology, Symptoms, Treatments. 2 (1970),73.
4.	orl-rat LD50:12,300 µg/kg	EXPEAM Experientia. 28 (1972),923.
5.	ihl-rat LC50:850 mg/m3/60M	BJIMAG British Journal of Industrial Medicine. 18 (1961),277.
6.	ipr-rat LD50:15 mg/kg	MELAAD Medicina del Lavoro. Industrial Medicine. 54 (1963),486.
7.	ivn-rat LD50:14,400 µg/kg	MELAAD Medicina del Lavoro. Industrial Medicine. 54 (1963),486.
8.	par-rat LD50:15 mg/kg	AOHYA3 Annals of Occupational Hygiene. 3 (1961),226.
9.	ihl-mus LCLo:650 mg/m3/7H	SAIGBL Sangyo Igaku. Japanese Journal of Industrial Health. 15 (1973),3.
10.	skn-dog LDLo:547 mg/kg	SAIGBL Sangyo Igaku. Japanese Journal of Industrial Health. 15 (1973),3.

TETRAETHYL LEAD Consensus Reports

IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 230.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 23 ,1980,p. 325.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 2 ,1973,p. 150.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Extremely Hazardous Substances List. Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

TETRAETHYL LEAD Safety Profile

Safety Information of TETRAETHYL LEAD(78-00-2):
Human poison by an unspecified route. Experimental poison by ingestion, intraperitoneal, intravenous, subcutaneous, and parenteral routes. Moderately toxic by inhalation and skin contact. Experimental teratogenic and reproductive effects. Questionable carcinogen with experimental carcinogenic data. Mutation data reported. Lead compounds are particularly toxic to the central nervous system. It is a solvent for fatty materials and has some solvent action on rubber as well. The fact that it is a lipoid solvent makes it an industrial hazard because it can cause intoxication not only by inhalation but also by absorption through the skin. Decomposes when exposed to sunlight or allowed to evaporate; forms triethyl lead, which is also a poisonous compound, as one of its decomposition products. May cause elemental lead intoxication by coming in contact with the skin.
A combustible liquid when exposed to heat, flame, or oxidizers. Can react vigorously with oxidizing materials. Exposure to air for several days may cause explosive decomposition. To fight fire, use dry chemical, CO₂, mist, foam. When heated to decomposition it emits toxic fumes of Pb. See also LEAD COMPOUNDS.
Hazard Codes T+,N
Risk Statements 61-26/27/28-33-50/53-62-38-10
Safety Statements 53-45-60-61-36/37-26
RIDADR UN 1649 6.1/PG 1
WGK Germany 3
RTECS TP4550000
TSCA Yes
HazardClass 6.1(a)
PackingGroup I

TETRAETHYL LEAD Standards and Recommendations

OSHA PEL: TWA 0.075 mg(Pb)/m³ (skin)
ACGIH TLV: TWA 0.1 mg(Pb)/m³ (skin); Not Classifiable as a Human Carcinogen
DFG MAK: 0.05 mg/m³
DOT Classification: 6.1; Label: Poison, Flammable Liquid

TETRAETHYL LEAD Analytical Methods

For occupational chemical analysis use NIOSH: Tetraethyl Lead (as Pb), 2533.

Product Name

TETRAETHYLLEAD

Synthetic route

TETRAETHYL LEAD Chemical Properties

TETRAETHYL LEAD Uses

TETRAETHYL LEAD Production

TETRAETHYL LEAD Toxicity Data With Reference

TETRAETHYL LEAD Consensus Reports

TETRAETHYL LEAD Safety Profile

TETRAETHYL LEAD Standards and Recommendations

TETRAETHYL LEAD Analytical Methods

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