Thiophene,2,4-dimethyl- supplier

Name
2,4-DIMETHYLTHIOPHENE
EINECS 211-312-3
CAS No. 638-00-6
Article Data25
CAS DataBase
Density 1.006 g/cm³
Solubility
Melting Point -66.9°C (estimate)
Formula C₆H₈S
Boiling Point 138.7 °C at 760 mmHg
Molecular Weight 112.196
Flash Point 23 °C
Transport Information UN 1993
Appearance
Safety 16
Risk Codes 10
Molecular Structure
Hazard Symbols
Synonyms 2,4-Dimethylthiophene;
PSA 28.24000
LogP 2.36490

Synthetic route

: 29421-92-9
4-bromo-2-methylthiophene

: 676-58-4
methylmagnesium chloride

: 638-00-6
2,4-dimethylthiophene

Conditions

Conditions	Yield
With 1,3-bis[(diphenylphosphino)propane]dichloronickel(II) In diethyl ether for 22h;	79%
1,3-bis[(diphenylphosphino)propane]dichloronickel(II) In tetrahydrofuran; diethyl ether Kumada coupling; Heating;

: 932-93-4
thiophene-2,4-dicarbaldehyde

: 638-00-6
2,4-dimethylthiophene

Conditions

Conditions	Yield
With potassium hydroxide; hydrazine hydrate In diethylene glycol	76%

: 616-44-4
3-Methylthiophene

: 74-88-4
methyl iodide

: 638-00-6
2,4-dimethylthiophene

Conditions

Conditions	Yield
Stage #1: 3-Methylthiophene With 2,2,6,6-tetramethylpiperidinyl-lithium In tetrahydrofuran; pentane at -78℃; for 1h; Stage #2: methyl iodide In tetrahydrofuran at -78 - 20℃; for 4h; Further stages.;	73%
Stage #1: 3-Methylthiophene With n-butyllithium; N,N,N,N,-tetramethylethylenediamine In diethyl ether; hexane at 0 - 20℃; for 3h; Stage #2: methyl iodide at 0 - 20℃; for 5h;	68%
Stage #1: 3-Methylthiophene With 2,2,6,6-tetramethyl-piperidine; tert.-butyl lithium In tetrahydrofuran; pentane at -78℃; for 1h; Stage #2: methyl iodide In tetrahydrofuran; pentane at -78 - 20℃; for 2h;

: 917-64-6
methyl magnesium iodide

: 29421-92-9
4-bromo-2-methylthiophene

: 638-00-6
2,4-dimethylthiophene

Conditions

Conditions	Yield
nickel 1,3-bis(diphenylphosphino)propane In diethyl ether for 22h; Heating;	66%

: 6030-36-0
4-methylthiophene-2-carbaldehyde

: 638-00-6
2,4-dimethylthiophene

Conditions

Conditions	Yield
Bildung ueber das Hydrazon;

: 78334-38-0
2,5-Dimethyl-[1,4]dithiin

: 638-00-6
2,4-dimethylthiophene

: 141-79-7
4-methyl-pent-3-en-2-one

: 638-00-6
2,4-dimethylthiophene

Conditions

Conditions	Yield
With sulfur at 200℃;

: 6641-83-4
2-methyl-4-oxopentanoic acid

: 638-00-6
2,4-dimethylthiophene

Conditions

Conditions	Yield
With diphosphorus trisulfide
With phosphorous (V) sulfide

: 1118-58-7
1,3-Dimethyl-1,3-butadien

: 638-00-6
2,4-dimethylthiophene

Conditions

Conditions	Yield
With sulfur at 260℃;

: 75-56-9, 16033-71-9
methyloxirane

: 638-00-6
2,4-dimethylthiophene

Conditions

Conditions	Yield
With aluminum oxide; hydrogen sulfide at 400℃;

: 554-14-3
2-Methylthiophene

: 593-53-3
Methyl fluoride

A: 632-16-6
2,3-dimethylthiophene

B: 638-00-6
2,4-dimethylthiophene

C: 638-02-8
2,5-DIMETHYLTHIOPHENE

Conditions

Conditions	Yield
With oxygen; trimethylamine In gas at 37.5℃; Product distribution; Kinetics; Mechanism; radiolysis: 1.5104 Gy at 5105 Gy h-1; variable pressures;

...Expand

: 554-14-3
2-Methylthiophene

A: 872-55-9
2-ethylthiophene

B: 638-00-6
2,4-dimethylthiophene

C: 638-02-8
2,5-DIMETHYLTHIOPHENE

D: 616-44-4
3-Methylthiophene

Conditions

Conditions	Yield
1.) glow discharge, 2.) -196 deg C -> -80 deg C; Further byproducts given. Title compound not separated from byproducts;	A 11.7 % Chromat. B 0.6 % Chromat. C 4.9 % Chromat. D 9.2 % Chromat.

...Expand

: 632-16-6
2,3-dimethylthiophene

A: 632-15-5
3,4-dimethylthiophene

B: 872-55-9
2-ethylthiophene

C: 638-00-6
2,4-dimethylthiophene

D: 616-44-4
3-Methylthiophene

Conditions

Conditions	Yield
1.) glow discharge, 2.) -196 deg C -> -80 deg C; Further byproducts given. Title compound not separated from byproducts;	A 2.3 % Chromat. B 1.5 % Chromat. C 1.5 % Chromat. D 12.8 % Chromat.

...Expand

: 632-15-5
3,4-dimethylthiophene

A: 188290-36-0
thiophene

B: 554-14-3
2-Methylthiophene

C: 638-00-6
2,4-dimethylthiophene

D: 108-88-3
toluene

Conditions

Conditions	Yield
1.) glow discharge, 2.) -196 deg C -> -80 deg C; Further byproducts given. Title compound not separated from byproducts;	A 1.9 % Chromat. B 1.4 % Chromat. C 6.2 % Chromat. D 2.4 % Chromat.

...Expand

: 632-15-5
3,4-dimethylthiophene

A: 632-16-6
2,3-dimethylthiophene

B: 638-00-6
2,4-dimethylthiophene

C: 638-02-8
2,5-DIMETHYLTHIOPHENE

D: 616-44-4
3-Methylthiophene

Conditions

Conditions	Yield
1.) glow discharge, 2.) -196 deg C -> -80 deg C; Further byproducts given. Title compound not separated from byproducts;	A 5.1 % Chromat. B 6.2 % Chromat. C 1.1 % Chromat. D 12.2 % Chromat.

...Expand

: 632-15-5
3,4-dimethylthiophene

A: 638-00-6
2,4-dimethylthiophene

B: 638-02-8
2,5-DIMETHYLTHIOPHENE

C: 616-44-4
3-Methylthiophene

D: 71-43-2
benzene

Conditions

Conditions	Yield
1.) glow discharge, 2.) -196 deg C -> -80 deg C; Further byproducts given. Title compound not separated from byproducts;	A 6.2 % Chromat. B 1.1 % Chromat. C 12.2 % Chromat. D 17.6 % Chromat.

...Expand

: 638-02-8
2,5-DIMETHYLTHIOPHENE

A: 554-14-3
2-Methylthiophene

B: 638-00-6
2,4-dimethylthiophene

C: 108-88-3
toluene

D: 71-43-2
benzene

Conditions

Conditions	Yield
1.) glow discharge, 2.) -196 deg C -> -80 deg C; Further byproducts given. Title compound not separated from byproducts;	A 15.4 % Chromat. B 3.3 % Chromat. C 2.6 % Chromat. D 36.9 % Chromat.

...Expand

: 616-44-4
3-Methylthiophene

A: 188290-36-0
thiophene

B: 632-16-6
2,3-dimethylthiophene

C: 638-00-6
2,4-dimethylthiophene

D: 71-43-2
benzene

Conditions

Conditions	Yield
1.) glow discharge, 2.) -196 deg C -> -80 deg C; Further byproducts given. Title compound not separated from byproducts;	A 13.6 % Chromat. B 13.6 % Chromat. C 1.7 % Chromat. D 7.7 % Chromat.

...Expand

: 616-44-4
3-Methylthiophene

A: 554-14-3
2-Methylthiophene

B: 632-16-6
2,3-dimethylthiophene

C: 632-15-5
3,4-dimethylthiophene

D: 638-00-6
2,4-dimethylthiophene

Conditions

Conditions	Yield
1.) glow discharge, 2.) -196 deg C -> -80 deg C; Further byproducts given. Title compound not separated from byproducts;	A 14.4 % Chromat. B 13.6 % Chromat. C 1.7 % Chromat. D 1.7 % Chromat.

...Expand

α-methyl-levulinic acid: α-methyl-levulinic acid

: 638-00-6
2,4-dimethylthiophene

Conditions

Conditions	Yield
With diphosphorus trisulfide

: 7783-06-4
hydrogen sulfide

: 75-56-9, 16033-71-9
methyloxirane

aluminium oxide: aluminium oxide

: 638-00-6
2,4-dimethylthiophene

Conditions

Conditions	Yield
at 400℃;

...Expand

: 1118-58-7
1,3-Dimethyl-1,3-butadien

sulfur: sulfur

: 638-00-6
2,4-dimethylthiophene

Conditions

Conditions	Yield
at 260℃;

: 616-44-4
3-Methylthiophene

: 74-88-4
methyl iodide

A: 632-16-6
2,3-dimethylthiophene

B: 638-00-6
2,4-dimethylthiophene

Conditions

Conditions	Yield
Stage #1: 3-Methylthiophene With methyllithium In tetrahydrofuran at 20℃; for 1h; Stage #2: methyl iodide In tetrahydrofuran at 20℃; Further stages.;
Stage #1: 3-Methylthiophene With n-butyllithium; N,N,N,N,-tetramethylethylenediamine In diethyl ether; hexane Stage #2: methyl iodide In diethyl ether; hexane Further stages. Title compound not separated from byproducts.;

...Expand

: 53119-60-1
2-bromo-4-methylthiophene

: 676-58-4
methylmagnesium chloride

: 638-00-6
2,4-dimethylthiophene

Conditions

Conditions	Yield
1,3-bis[(diphenylphosphino)propane]dichloronickel(II) In tetrahydrofuran; diethyl ether Kumada coupling; Heating;

: 765-58-2
2-bromo-5-methyl thiophene

: 638-00-6
2,4-dimethylthiophene

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: LDA / tetrahydrofuran; hexane / 2 h / -78 °C 1.2: 80 percent / methanol / tetrahydrofuran; hexane 2.1: 79 percent / Ni(dppp)Cl2 / diethyl ether / 22 h View Scheme

: 616-44-4
3-Methylthiophene

: 638-00-6
2,4-dimethylthiophene

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: butyl lithium; diethyl ether / Behandeln mit Dimethylformamid und Hydrolysieren 2: Bildung ueber das Hydrazon View Scheme

: 78519-11-6
2,4-dimethyl-2,5-dihydrothiophene

: 638-00-6
2,4-dimethylthiophene

Conditions

Conditions	Yield
With bunazosin In benzene

: 29421-92-9
4-bromo-2-methylthiophene

: 75-16-1
methylmagnesium bromide

: 638-00-6
2,4-dimethylthiophene

Conditions

Conditions	Yield
With [1,1'-bis(diphenylphosphino)ferrocene]nickel(II) chloride In diethyl ether for 24h; Inert atmosphere; Reflux;

: 188290-36-0
thiophene

: 624-92-0
Dimethyldisulphide

A: 554-14-3
2-Methylthiophene

B: 632-15-5
3,4-dimethylthiophene

C: 638-00-6
2,4-dimethylthiophene

D: 1795-04-6
2,3,4-trimethylthiophene

E: 638-02-8
2,5-DIMETHYLTHIOPHENE

F: 14503-51-6
tetramethylthiophene

G: 616-44-4
3-Methylthiophene

H: 74-93-1
methylthiol

I: 75-18-3
dimethylsulfide

J: 7783-06-4
hydrogen sulfide

Conditions

Conditions	Yield
With Co/HZSM-5 at 300℃; under 760.051 Torr; Inert atmosphere; Flow reactor;

...Expand

: 638-00-6
2,4-dimethylthiophene

: 63862-00-0
2,4-dibromo-3,5-dimethylthiophene

Conditions

Conditions	Yield
With bromine for 0.05h; Ambient temperature;	96%
With bromine In acetic acid	65%
With carbon disulfide; bromine Erwaermen des Reaktionsprodukts mit methanol. Kalilauge;

: 638-00-6
2,4-dimethylthiophene

: 6030-36-0
4-methylthiophene-2-carbaldehyde

Conditions

Conditions	Yield
With n-butyllithium In tetrahydrofuran; hexane at -78 - 20℃; for 2.5h; Inert atmosphere;	95%

: 638-00-6
2,4-dimethylthiophene

: 58047-43-1
N,N-bis(4-methylphenyl)-N-(4-iodophenyl) amine

: 2,4-dimethyl-5-(4-(N,N'-bis(4-methylphenyl)amino)phenyl)thiophene

Conditions

Conditions	Yield
Stage #1: 2,4-dimethylthiophene With n-butyllithium; N,N,N,N,-tetramethylethylenediamine In diethyl ether; hexane at 20℃; for 2h; Stage #2: With zinc(II) chloride In diethyl ether at 20℃; for 5h; Stage #3: N,N-bis(4-methylphenyl)-N-(4-iodophenyl) amine; tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 20 - 50℃; for 7h;	92%

: 638-00-6
2,4-dimethylthiophene

: 591-50-4
iodobenzene

: 57021-49-5
2,4-dimethyl-5-phenylthiophene

Conditions

Conditions	Yield
Stage #1: 2,4-dimethylthiophene With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; zinc(II) chloride In diethyl ether; hexane at -30 - 20℃; for 6h; Metallation; Stage #2: iodobenzene; tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran; diethyl ether; hexane at 50℃; for 12h; Phenylation;	90%
Yield given. Multistep reaction;

: 638-00-6
2,4-dimethylthiophene

: 2,4-dimethyl-5-chloro-thiophene

Conditions

Conditions	Yield
With sulfuryl dichloride In dichloromethane for 2h; Reflux;	85%
	28%
With sulfuryl dichloride In dichloromethane

: 638-00-6
2,4-dimethylthiophene

: 13041-70-8
(E)-4-bromostilbene

: 3,5-dimethyl-2-(4-styrylphenyl)thiophene

Conditions

Conditions	Yield
Stage #1: 2,4-dimethylthiophene With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; zinc(II) chloride In diethyl ether; hexane at -30 - 20℃; for 6h; Metallation; Stage #2: (E)-4-bromostilbene; tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran; diethyl ether; hexane at 50℃; for 12h; Arylation;	80%

: 638-00-6
2,4-dimethylthiophene

: 68-12-2, 33513-42-7
N,N-dimethyl-formamide

: 85895-83-6
3,5-dimethyl-2-thiophenecarboxaldehyde

Conditions

Conditions	Yield
With trichlorophosphate 1.) r.t., 1 h, 2.) heating, 30 min;	77%
With trichlorophosphate at 70 - 75℃; for 3h;	66%
With diethyl ether anschliessendes Hydrolysieren;

: 638-00-6
2,4-dimethylthiophene

: 407-25-0
trifluoroacetic anhydride

: 65613-26-5
1-(3,5-dimethylthiophen-2-yl)-2,2,2-trifluoroethanone

Conditions

Conditions	Yield
With magnesium perchlorate dihydrate In 1,2-dichloro-ethane at 60℃; for 12h; Friedel-Crafts Acylation; regioselective reaction;	76%

: 679806-34-9
3,5-dimethylthiophene-2-carbonyl chloride

: 638-00-6
2,4-dimethylthiophene

: 910479-27-5
bis(3,5-dimethyl-2-thienyl) ketone

Conditions

Conditions	Yield
With aluminium trichloride In dichloromethane for 4h;	72%

: 638-00-6
2,4-dimethylthiophene

: 1663-39-4
tert-Butyl acrylate

: tert-butyl (E)-3-(3,5-dimethylthiophen-2-yl)acrylate

Conditions

Conditions	Yield
With 4-(ethylthio)-N,N-dimethylaniline; palladium diacetate; acetic acid; hydroquinone at 60℃; for 3h;	65%

: 638-00-6
2,4-dimethylthiophene

: 3,3',5,5'-tetramethyl-2,2'-bithiophene

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate; bis-[(trifluoroacetoxy)iodo]benzene In dichloromethane at -78℃; for 3h; Inert atmosphere;	44%
With boron trifluoride diethyl etherate; bis-[(trifluoroacetoxy)iodo]benzene In dichloromethane at -78℃;	44 % Chromat.

: 638-00-6
2,4-dimethylthiophene

: 79-37-8
oxalyl dichloride

: 779332-89-7
1,2-bis(3,5-dimethyl-2-thienyl)ethane-1,2-dione

Conditions

Conditions	Yield
With aluminium trichloride In n-heptane; 1,2-dichloro-ethane at -20℃; for 2.3h; Friedel-Crafts reaction;	44%

: 638-00-6
2,4-dimethylthiophene

: 615-36-1
2-bromoaniline

: 106183-35-1
2-(2'-bromophenyl)-3,5-dimethylthiophene

Conditions

Conditions	Yield
With isopentyl nitrite at 70℃; for 4h;	43%

: 638-00-6
2,4-dimethylthiophene

: 1309657-46-2
1-(2,3,3,4,4,5,5-Heptafluoro-1-cyclopenten-1-yl)-2-methylnaphthalene

: 1628556-77-3
3,5-dimethyl-2-[3,3,4,4,5,5-hexafluoro-2-(2-methyl-1-naphthalenyl)-1-cyclopenten-1-yl]thiophene

Conditions

Conditions	Yield
Stage #1: 2,4-dimethylthiophene With N,N,N,N,-tetramethylethylenediamine In diethyl ether at 0℃; Inert atmosphere; Stage #2: With n-butyllithium In diethyl ether; hexane Inert atmosphere; Reflux; Stage #3: 1-(2,3,3,4,4,5,5-Heptafluoro-1-cyclopenten-1-yl)-2-methylnaphthalene In diethyl ether; hexane at -70 - 20℃; Inert atmosphere;	43%

: 638-00-6
2,4-dimethylthiophene

: 360561-22-4
1-[2,4-dimethyl-5-(2'',4'',5''-triphenylimidazolyl-4'-yl)-3-thienyl]perfluorocyclopentene

: 360773-76-8
1-(3,5-dimethyl-2-thienyl)-2-[2,4-dimethyl-5-(2'',4'',5''-triphenylimidazol-4'-yl)-3-thienyl]perfluorocyclopentene

Conditions

Conditions	Yield
Stage #1: 2,4-dimethylthiophene With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.5h; Stage #2: 1-[2,4-dimethyl-5-(2'',4'',5''-triphenylimidazolyl-4'-yl)-3-thienyl]perfluorocyclopentene In tetrahydrofuran at -78℃; for 1h; Further stages.;	42%

: 638-00-6
2,4-dimethylthiophene

: 246222-31-1
3,3-dimethoxy-4-oxo-cyclohexa-1,5-dienecarbonitrile

A: 4-(3,5-dimethyl-thiophen-2-yloxy)-3-methoxy-benzonitrile

: (1S,2S,6S,7S)-10,10-Dimethoxy-4,6-dimethyl-11-oxo-3-thia-tricyclo[5.2.2.02,6]undeca-4,8-diene-9-carbonitrile

Conditions

Conditions	Yield
for 5h; Diels-Alder reaction; Heating;	A 3% B 40%

...Expand

: 638-00-6
2,4-dimethylthiophene

: 219755-75-6
4-acetyl-6,6-dimethoxy-cyclohexa-2,4-dienone

A: 1-[2-(3,5-dimethyl-thiophen-2-yl)-4-hydroxy-3-methoxy-phenyl]-ethanone

: (1S,2S,6S,7S)-10-Acetyl-9,9-dimethoxy-4,6-dimethyl-3-thia-tricyclo[5.2.2.02,6]undeca-4,10-dien-8-one

Conditions

Conditions	Yield
for 5h; Diels-Alder reaction; Heating;	A 33% B 21%

...Expand

: 638-00-6
2,4-dimethylthiophene

: 124667-66-9
3,3-dimethoxy-4-oxo-cyclohexa-1,5-dienecarboxylic acid methyl ester

A: 4-(3,5-dimethyl-thiophen-2-yloxy)-3-methoxy-benzoic acid methyl ester

B: 2-(3,5-dimethyl-thiophen-2-yl)-4-hydroxy-3-methoxy-benzoic acid methyl ester

: (1S,2S,6S,7S)-10,10-Dimethoxy-4,6-dimethyl-11-oxo-3-thia-tricyclo[5.2.2.02,6]undeca-4,8-diene-9-carboxylic acid methyl ester

Conditions

Conditions	Yield
for 5h; Diels-Alder reaction; Heating;	A 6% B 12% C 32%

...Expand

: 638-00-6
2,4-dimethylthiophene

: 107-30-2
chloromethyl methyl ether

: 133296-08-9
2,4-bis(chloromethyl)-3,5-dimethylthiophene

Conditions

Conditions	Yield
With titanium tetrachloride In carbon disulfide Ambient temperature;	22%

: 638-00-6
2,4-dimethylthiophene

: 463-72-9
carbamic chloride

: 98547-25-2
3,5-dimethyl-thiophene-2-carboxylic acid amide

Conditions

Conditions	Yield
With carbon disulfide; aluminium trichloride

: 638-00-6
2,4-dimethylthiophene

: 108-24-7
acetic anhydride

: 50382-14-4
1-(3,5-dimethyl-[2]thienyl)-ethanone

Conditions

Conditions	Yield
With phosphoric acid; benzene

: 638-00-6
2,4-dimethylthiophene

: 75-36-5
acetyl chloride

: 2530-10-1
3-Acetyl-2,5-dimethylthiophen

Conditions

Conditions	Yield
With tin(IV) chloride; benzene

: 638-00-6
2,4-dimethylthiophene

: 2-iodo-3,5-dimethyl-thiophene

Conditions

Conditions	Yield
With iodine; mercury(II) oxide; benzene

: 638-00-6
2,4-dimethylthiophene

: 85895-83-6
3,5-dimethyl-2-thiophenecarboxaldehyde

Conditions

Conditions	Yield
With n-butyllithium; diethyl ether

: 638-00-6
2,4-dimethylthiophene

: 3,5-dimethyl-thiophene-2,4-disulfonyl chloride

Conditions

Conditions	Yield
With sulfuric acid; sulfur trioxide Erwaermen des Dinatrium-Salzes der erhaltenen Disulfonsaeure mit Phosphor(V)-chlorid;

: 638-00-6
2,4-dimethylthiophene

: 3-hydroxy-3,5-dimethyl-2,3-dihydro-[2]thienylmercury (1+); mercury chloride-double salt of chloride

Conditions

Conditions	Yield
With ethanol; sodium acetate; mercury dichloride

Thiophene,2,4-dimethyl- Specification

The Thiophene, 2, 4-dimethyl-, with the CAS registry number 638-00-6, is also known as 2, 4-Dimethyl thiophene. Its EINECS registry number is 211-312-3. This chemical's molecular formula is C₆H₈S and molecular weight is 112.19. What's more, its IUPAC name is 2, 4-Dimethylthiophene. Besides, this chemical is highly flammable, and it may catch fire on contacting with an ignition source. Hence, keep it away from sources of ignition.

Physical properties about Thiophene, 2, 4-dimethyl- are: (1)ACD/LogP: 2.82; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.82; (4)ACD/LogD (pH 7.4): 2.82; (5)ACD/BCF (pH 5.5): 81.38; (6)ACD/BCF (pH 7.4): 81.38; (7)ACD/KOC (pH 5.5): 811.24; (8)ACD/KOC (pH 7.4): 811.24; (9)#H bond acceptors: 0; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 28.24 Å²; (13)Index of Refraction: 1.527; (14)Molar Refractivity: 34.28 cm³; (15)Molar Volume: 111.4 cm³; (16)Polarizability: 13.59×10^-24 cm³; (17)Surface Tension: 32.2 dyne/cm; (18)Density: 1.006 g/cm³; (19)Flash Point: 23 °C; (20)Enthalpy of Vaporization: 36.05 kJ/mol; (21)Boiling Point: 138.7 °C at 760 mmHg; (22)Vapour Pressure: 8.26 mmHg at 25 °C.

Preparation of Thiophene, 2, 4-dimethyl-: this chemical is prepared by reaction of 4-Bromo-2-methyl-thiophene with Methylmagnesium iodide by heating. This reaction needs catalyst Nickel 1, 3-bis(diphenylphosphino)propane and solvent Diethyl ether. The reaction time is 22 hours. The yield is about 66 %.

Uses of Thiophene, 2, 4-dimethyl-: it is used to produce other chemicals. For example, it is used to produce 2, 4-Dibromo-3, 5-dimethyl-thiophene at ambient temperature. The reaction needs reagent Br₂. The reaction time is 3 minutes. The yield is about 96 %.

Thiophene, 2, 4-dimethyl- can be used to produce 2, 4-Dibromo-3, 5-dimethyl-thiophene.

You can still convert the following datas into molecular structure:
(1) SMILES: s1c(cc(c1)C)C
(2) InChI: InChI=1/C6H8S/c1-5-3-6(2)7-4-5/h3-4H,1-2H3
(3) InChIKey: CPULIKNSOUFMPL-UHFFFAOYAR

Product Name

2,4-DIMETHYLTHIOPHENE

Synthetic route

Thiophene,2,4-dimethyl- Specification

Related Products

Hot Products