Triethylamine supplier | CasNO.121-44-8

Name
Triethylamine
EINECS 204-469-4
CAS No. 121-44-8
Article Data339
CAS DataBase
Density 0.75 g/cm³
Solubility water: 133 g/L (20 °C)
Melting Point -115 °C
Formula C₆H₁₅N
Boiling Point 90.495 °C at 760 mmHg
Molecular Weight 101.192
Flash Point 20°F
Transport Information UN 1296 3/PG 2
Appearance colorless liquid
Safety 3-16-26-29-36/37/39-45
Risk Codes 11-20/21/22-35
Molecular Structure
Hazard Symbols F,C
Synonyms Triethylamine(7CI,8CI);(Diethylamino)ethane;N,N-Diethylethanamine;AI3-15425;CCRIS 4881;Ethanamine, N,N-diethyl-;HSDB 896;Triaethylamin;Trietilamina;
PSA 3.24000
LogP 1.34810

Synthetic route

: 2687-45-8
triethylamine N-oxide

: 121-44-8
triethylamine

Conditions

Conditions	Yield
With carbon monoxide; 1 wt% Au/TiO2; water In acetone at 60℃; under 7600.51 Torr; for 10h; Autoclave;	99%
With C55H43P3Rh(1+)*C32H12BF24(1-); isopropyl alcohol at 80℃; for 24h; Inert atmosphere;	98%
With titanium tetrachloride; sodium iodide In acetonitrile at 20℃; for 0.0833333h;	55%

: 349-76-8
3'-(trifluoromethyl)acetophenone

A: 454-91-1, 68120-40-1, 96789-80-9, 127852-24-8
(R)-1-(3-trifluoromethylphenyl)ethanol

B: 121-44-8
triethylamine

Conditions

Conditions	Yield
	A 99% B n/a

: 111-87-5
octanol

: 64-17-5
ethanol

: 75-05-8
acetonitrile

A: 4088-37-3
diethyloctylamine

B: 121-44-8
triethylamine

Conditions

Conditions	Yield
With hydrogen; copper at 240℃; under 7600 Torr;	A 95% B n/a

...Expand

: 64-17-5
ethanol

: 112-30-1
1-Decanol

: 75-05-8
acetonitrile

A: 6308-94-7
n-decyldiethylamine

B: 121-44-8
triethylamine

Conditions

Conditions	Yield
With hydrogen; copper at 240℃; under 7600 Torr;	A 90% B n/a

...Expand

: 64-17-5
ethanol

: 112-53-8
1-dodecyl alcohol

: 75-05-8
acetonitrile

A: 4271-27-6
diethyllaurylamine

B: 121-44-8
triethylamine

Conditions

Conditions	Yield
With hydrogen; copper at 240℃; under 7600 Torr;	A 85% B n/a

...Expand

: 58608-53-0
1,2-bis(dicyanomethylene)-3-triethylammonium cyclopropanide

: 99968-57-7
2,3-Di-piperidin-1-yl-cycloprop-2-eneselone

A: C22H20N6Se

B: 121-44-8
triethylamine

Conditions

Conditions	Yield
In dichloromethane for 1h; Heating;	A 84% B n/a

...Expand

: 629-76-5
pentadecanol

: 64-17-5
ethanol

: 75-05-8
acetonitrile

A: 36555-73-4
Diaethyl-pentadecyl-amin

B: 121-44-8
triethylamine

Conditions

Conditions	Yield
With hydrogen; copper at 240℃; under 7600 Torr;	A 80% B n/a

...Expand

: 64-17-5
ethanol

: 36653-82-4
1-Hexadecanol

: 75-05-8
acetonitrile

A: 30951-88-3
N,N-diethylhexadecyl tertiary amine

B: 121-44-8
triethylamine

Conditions

Conditions	Yield
With hydrogen; copper at 240℃; under 7600 Torr;	A 80% B n/a

...Expand

: 87-90-1
trichloroisocyanuric acid

: 121-44-8
triethylamine

Conditions

Conditions	Yield
In dichloromethane	80%

: 109-89-7
diethylamine

: 121-44-8
triethylamine

Conditions

Conditions	Yield
With chlorohydridocarbonylbis(tricyclohexylphosphine)ruthenium(II) In toluene at 120℃; for 24h; Schlenk technique; Inert atmosphere;	79%

: 64-17-5
ethanol

: 112-70-9
tridecan-1-ol

: 75-05-8
acetonitrile

A: 66577-48-8
diethyl-tridecyl-amine

B: 121-44-8
triethylamine

Conditions

Conditions	Yield
With hydrogen; copper at 240℃; under 7600 Torr;	A 78% B n/a

...Expand

: 64-17-5
ethanol

: 112-72-1
1-Tetradecanol

: 75-05-8
acetonitrile

A: 7307-58-6
N,N-diethyltetradecan-1-amine

B: 121-44-8
triethylamine

Conditions

Conditions	Yield
With hydrogen; copper at 240℃; under 7600 Torr;	A 77% B n/a

...Expand

: 100-44-7
benzyl chloride

: 121-44-8
triethylamine

: 56-37-1
N-benzyl-N,N,N-triethylammonium chloride

Conditions

Conditions	Yield
at 20℃;	100%
In acetonitrile for 1h; Reflux;	95%
	75%

: 75-11-6
diiodomethane

: 121-44-8
triethylamine

: 104304-17-8
1-iodo-N,N,N-triethylmethaniminium iodide

Conditions

Conditions	Yield
In acetonitrile at 28℃; under 3750300 Torr; for 19h;	100%
	92%
With hydroquinone In ethyl acetate at 20℃; for 48h; Alkylation;	47.7%
With ethanol at 100℃; im geschlossenen Rohr;

: 121-44-8
triethylamine

: 106-95-6
allyl bromide

: 29443-23-0
N,N,N-triethylprop-2-en-1-aminium bromide

Conditions

Conditions	Yield
In ethanol at 95℃; for 48h;	100%
for 2h; Reflux;	92%

: 121-44-8
triethylamine

: 74-88-4
methyl iodide

: 994-29-6
triethylmethylammonium iodide

Conditions

Conditions	Yield
With Hexamethyldisiloxane at 20℃; for 24h; Solvent; Green chemistry;	100%
In butanone at 20℃; Menshutkin reaction;	85%
In methanol; acetonitrile at 30℃; Thermodynamic data; Rate constant; ΔH(excit.), ΔS(excit.); ratio of solvents; transfer enthalpies of activated complex;

: 1120-71-4
1,3-propanesultone

: 121-44-8
triethylamine

: 1887-93-0
N-(3-sulfonatopropyl)-N,N,N-triethylammonium

Conditions

Conditions	Yield
In toluene at 90℃; for 12h;	100%
In 1,2-dichloro-ethane at 40℃; for 6h;	98.5%
In ethanol at 20℃; for 12h; Inert atmosphere;	96%

: 110-89-4
piperidine

: 75-15-0
carbon disulfide

: 121-44-8
triethylamine

: 59983-55-0
triethylammonium piperidinodithiocarbamate

Conditions

Conditions	Yield
In diethyl ether at 20℃; for 0.2h;	100%
In acetonitrile
In diethyl ether

...Expand

: 116-63-2
1-amino-2-naphthol-4-sulfonic acid

: 555-16-8
4-nitrobenzaldehdye

: 121-44-8
triethylamine

: triethylammonium 3-hydroxy-4-(4-nitrobenzylidene)amino-1-naphthalenesulfonate

Conditions

Conditions	Yield
In ethanol for 1h; Heating;	100%

...Expand

: 72142-16-6
(3-methyl-2-butenyl)trimethoxysilane

: 120-80-9
benzene-1,2-diol

: 121-44-8
triethylamine

: 114571-77-6
triethylammonium bis(catecholato)(3-methyl-2-butenyl)siliconate

Conditions

Conditions	Yield
at 45℃; for 5h;	100%

...Expand

: 2551-83-9
allyltrimethoxysilane

: 120-80-9
benzene-1,2-diol

: 121-44-8
triethylamine

: 114612-18-9
triethylammonium bis(pyrocatecholato)allylsilicate

Conditions

Conditions	Yield
for 5h; room temperature to 40 deg C;	100%
at 40℃; for 4h; Inert atmosphere; Sealed tube;	55%

...Expand

: 125715-25-5
(2-methyl-2-propenyl)trimethoxysilane

: 120-80-9
benzene-1,2-diol

: 121-44-8
triethylamine

: 125715-30-2
triethylammonium bis(catecholato)(2-methyl-2-propenyl)siliconate

Conditions

Conditions	Yield
at 45℃; for 5h;	100%

...Expand

: 13436-83-4
2-Butenyltrimethoxysilane

: 120-80-9
benzene-1,2-diol

: 121-44-8
triethylamine

: triethylammonium bis(catecholato)-2-butenylsiliconate

Conditions

Conditions	Yield
at 45℃; for 5h;	100%

...Expand

: 31125-04-9
3-(N,N-Dimethylamino)phenyl isocyanate

: 68-11-1
mercaptoacetic acid

: 121-44-8
triethylamine

: 79479-15-5
(3-dimethylaminophenylaminocarbonylthio)acetic acid triethylammonium salt

Conditions

Conditions	Yield
In chloroform for 16h;	100%

...Expand

: 354-32-5
trifluoracetyl chloride

: 503-39-9
di-H-trifluoroethane-2-sulfonyl fluoride

: 121-44-8
triethylamine

: (Z)-1,1,1,4,4,4-Hexafluoro-3-hydroxy-but-2-ene-2-sulfonyl fluoride; compound with triethyl-amine

Conditions

Conditions	Yield
In diethyl ether at -70 - 20℃;	100%

...Expand

: 18997-19-8
Chloromethyl pivalate

: 121-44-8
triethylamine

: (2,2-Dimethyl-propionyloxymethyl)-triethyl-ammonium; chloride

Conditions

Conditions	Yield
In acetonitrile at 70℃;	100%

: 5524-45-8
α-(N-hydroxy)aminoisobutyric acid

: 127043-29-2
N-(1-Methyl-2-oxo-ethyl)-2-phenyl-acetamide

: 121-44-8
triethylamine

: 130304-14-2
C15H20N2O4*C6H15N

Conditions

Conditions	Yield
With 3 A molecular sieve In dichloromethane for 5h; Heating;	100%

...Expand

: 676-83-5
methyldichlorophosphane

: 121-44-8
triethylamine

: 142088-47-9
Triethylammonium methylphosphinate

Conditions

Conditions	Yield
With water In acetonitrile at 0℃; for 0.416667h;	100%
With water In acetonitrile at 0℃; for 0.25h;

: 375-16-6
heptafluorobutyryl chloride

: 503-39-9
di-H-trifluoroethane-2-sulfonyl fluoride

: 121-44-8
triethylamine

: (Z)-1,1,1,4,4,5,5,6,6,6-Decafluoro-3-hydroxy-hex-2-enesulfonyl fluoride; compound with triethyl-amine

Conditions

Conditions	Yield
In diethyl ether at -70 - 20℃;	100%

...Expand

: 375-60-0
perfluorovaleryl chloride

: 503-39-9
di-H-trifluoroethane-2-sulfonyl fluoride

: 121-44-8
triethylamine

: (Z)-1,1,1,4,4,5,5,6,6,7,7,7-Dodecafluoro-3-hydroxy-hept-2-enesulfonyl fluoride; compound with triethyl-amine

Conditions

Conditions	Yield
In diethyl ether at -70 - 20℃;	100%

...Expand

: 2127-74-4
1,2,2,2-tetrafluoro-ethanesulfonyl fluoride

: 684-22-0
bis(trifluoromethyl)ketene

: 121-44-8
triethylamine

: 86797-27-5
1,1,1,2,5,5,5-Heptafluoro-3-hydroxy-4-trifluoromethyl-pent-3-enesulfonyl fluoride; compound with triethyl-amine

Conditions

Conditions	Yield
In diethyl ether at -35 - 20℃;	100%

...Expand

: 5335-05-7
chloromethyl benzoate

: 121-44-8
triethylamine

: <(benzyloxy)methyl>triethylammonium chloride

Conditions

Conditions	Yield
In acetonitrile at 70℃;	100%

: 61368-82-9
Bis-(phenylsulfonyl)-methyldiphenylphosphinoxid

: 121-44-8
triethylamine

: 83252-97-5
C25H21O5PS2*C6H15N

Conditions

Conditions	Yield
	100%

: 122417-62-3
Phosphoric acid dihexyl-phosphinoylmethyl ester 2-ethyl-hexyl ester 1-methyl-2-oxo-propyl ester

: 121-44-8
triethylamine

: 129583-08-0
Phosphoric acid dihexyl-phosphinoylmethyl ester 2-ethyl-hexyl ester; compound with triethyl-amine

Conditions

Conditions	Yield
With pyridine In water at 15℃; for 92h;	100%

: 129908-16-3
methyl 2,6-anhydro-3,8-dideoxy-8-oximino-D-glycero-D-talo-octonate

: 121-44-8
triethylamine

: 129908-45-8, 130335-63-6
2,6-anhydro-3,8-dideoxy-8-oximino-D-glycero-D-talo-octonic acid triethylammonium salt

Conditions

Conditions	Yield
With water for 18h; Ambient temperature;	100%

: 130148-82-2
3-Azido-2-cyan-3-(1-ethoxycarbonyl-3-methylthiopropylamino)acrylsaeure-methylester

: 121-44-8
triethylamine

: 130149-12-1
(E)-2-Cyan-2-<1-(1-ethoxycarbonyl)-3-methylthiopropyl)-4,5-dihydro-1H-tetrazol-5-yliden>essigsaeure-methylester, Triethylammonium-Salz

Conditions

Conditions	Yield
In dichloromethane for 3h; Ambient temperature;	100%

: 130149-41-6
3,3'-<(1-Methoxycarbonyl)-1,5-pentandiyldiimino>bis(3-azido-2-cyanacrylsaeure-methylester)

: 121-44-8
triethylamine

: 130196-41-7
(E)-2,2'-<<1-(Methoxycarbonyl)-1,5-pentandiyl>di-4,5-dihydro-1H-tetrazol-1-yl-5-yliden>bis(cyanessigsaeure-methylester), Bis(triethylammonium)-Salz

Conditions

Conditions	Yield
In dichloromethane for 3h; Ambient temperature;	100%

: 130148-87-7
3,3'-Dithiobis<(1-methoxycarbonyl)-2,1-ethanediyldiimino>bis(3-azido-2-cyanacrylsaeure-methylester)

: 121-44-8
triethylamine

: 130149-22-3
(E)-2,2'-Dithio(<1-(methoxycarbonyl)-2,1-ethanediyl>-di-4,5-dihydro-1H-tetrazol-1-yl-5-yliden)bis(cyanessigsaeure-methylester), Bis(triethylammonium)-Salz

Conditions

Conditions	Yield
In dichloromethane for 3h; Ambient temperature;	100%

: 76847-41-1
3-bromo-4,5-dihydro-5-hydroperoxy-4,4-dimethyl-3,5-diphenyl-3H-pyrazole

: 121-44-8
triethylamine

A: 2687-45-8
triethylamine N-oxide

B: 76847-42-2
3-bromo-4,5-dihydro-5-hydroxy-4,4-dimethyl-3,5-diphenyl-3H-pyrazole

Conditions

Conditions	Yield
In acetone at 34℃; Rate constant; k2= 2.3E-2M-1sec-1;	A 100% B n/a
In chloroform-d1 at 34℃; Rate constant;	A 100 % Spectr. B n/a

...Expand

: 81671-11-6
C119H188Br3ClO22P2

: 121-44-8
triethylamine

: C117H187ClO22P2*C6H15N

Conditions

Conditions	Yield
With 2,4,6-tri(iso-propyl)benzenesulfonic acid; zinc In pyridine at 40℃; for 0.166667h;	100%

: 108201-68-9
2-picryloxy-3,5-di-tert-butyl phenol

: 108201-69-0
2-picryloxy-4,6-di-tert-butyl phenol

: 121-44-8
triethylamine

: C20H22N3O8(1-)*C6H15N*H(1+)

Conditions

Conditions	Yield
triethylamine In diethyl ether for 0.166667h; Ambient temperature;	100%

...Expand

: 106502-51-6
Dithiophosphoric acid O-{(2R,3S,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-[(3-imidazol-1-ylmethyl-phenyl)-bis-(4-methoxy-phenyl)-methoxymethyl]-tetrahydro-furan-3-yl} ester S,S'-diphenyl ester

: 121-44-8
triethylamine

: 106502-57-2
Thiophosphoric acid O-{(2R,3S,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-[(3-imidazol-1-ylmethyl-phenyl)-bis-(4-methoxy-phenyl)-methoxymethyl]-tetrahydro-furan-3-yl} ester S-phenyl ester; compound with triethyl-amine

Conditions

Conditions	Yield
With pyridine; hypophosphorous acid for 0.166667h;	100%

Triethylamine Chemical Properties

Molecular Structure:

Molecular Formula: C₆H₁₅N
Molecular Weight: 101.19
IUPAC Name: N,N-Diethylethanamine
Synonyms of Triethylamine (CAS NO.121-44-8): (Diethylamino)ethane ; AI3-15425 ; CCRIS 4881 ; EINECS 204-469-4 ; Ethanamine, N,N-diethyl- ; HSDB 896 ; N,N-Diethylethanamine ; TEA ; TEN ; Triaethylamin ; Triaethylamin [German] ; Trietilamina ; Trietilamina [Italian] ; Triethylamine [UN1296] [Flammable liquid] ; UN1296
CAS NO: 121-44-8
Classification Code: Human Data ; Mutation data ; Skin / Eye Irritant ; Tumor data
Melting point: -115 °C
Index of Refraction: 1.412
Molar Refractivity: 33.56 cm³
Molar Volume: 134.8 cm³
Surface Tension: 23.4 dyne/cm
Density: 0.75 g/cm³
Enthalpy of Vaporization: 31.01 kJ/mol
Boiling Point: 90.5 °C at 760 mmHg
Vapour Pressure: 56.1 mmHg at 25°C

Triethylamine Uses

Triethylamine (CAS NO.121-44-8) is commonly used in organic synthesis as a base, most often in the preparation of amides and esters from acyl chlorides. Like other tertiary amines it catalyzes the formation of urethane foams and epoxy resins. It is also useful in dehydrohalogenation reactions and Swern oxidations. It is also the active ingredient for FlyNap, a product for anesthetizing Drosophila melanogaster.

Triethylamine Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LCLo	inhalation	1000ppm/4H (1000ppm)		Journal of Industrial Hygiene and Toxicology. Vol. 30, Pg. 2, 1948.
human	TCLo	inhalation	6500ug/m3/4H (6.5mg/m3)	SENSE ORGANS AND SPECIAL SENSES: VISUAL FIELD CHANGES: EYE SENSE ORGANS AND SPECIAL SENSES: CORNEAL DAMAGE: EYE SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE	Occupational and Environmental Medicine. Vol. 56, Pg. 1, 1999.
human	TCLo	inhalation	12mg/m3/11W-C (12mg/m3)	SENSE ORGANS AND SPECIAL SENSES: VISUAL FIELD CHANGES: EYE	International Archives of Occupational and Environmental Health. Vol. 57, Pg. 297, 1986.
human	TCLo	inhalation	20mg/m3/8H (20mg/m3)	SENSE ORGANS AND SPECIAL SENSES: CORNEAL DAMAGE: EYE	Weisheng Dulixue Zazhi. Journal of Health Toxicology. Vol. 4, Pg. 45, 1990.
mammal (species unspecified)	LC50	inhalation	6gm/m3 (6000mg/m3)		Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 14, Pg. 80, 1975.
mouse	LC50	inhalation	6gm/m3 (6000mg/m3)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES LIVER: FATTY LIVER DEGERATION	Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 7, Pg. 56, 1965.
mouse	LD50	intraperitoneal	405mg/kg (405mg/kg)		Yakugaku Zasshi. Journal of Pharmacy. Vol. 97, Pg. 1117, 1977.
mouse	LD50	oral	546mg/kg (546mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: EXCITEMENT	Hygiene and Sanitation Vol. 30(7-9), Pg. 351, 1965.
rabbit	LD50	skin	570uL/kg (0.57mL/kg)		AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951.
rat	LCLo	inhalation	1000ppm/4H (1000ppm)		AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951.
rat	LD50	oral	460mg/kg (460mg/kg)		AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951.
rat	LDLo	intraperitoneal	75mg/kg (75mg/kg)		Farmakologiya i Toksikologiya Vol. 31, Pg. 238, 1968.

Triethylamine Safety Profile

Hazard Codes of Triethylamine (CAS NO.121-44-8): F, Corrosive C
Risk Statements: 11-20/21/22-35
R11: Highly flammable.
R20/22: Harmful by inhalation and if swallowed.
R35: Causes severe burns.
Safety Statements: 3-16-26-29-36/37/39-45
S3: Keep in a cool place.
S16: Keep away from sources of ignition.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S29: Do not empty into drains.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 1296 3/PG 2
WGK Germany: 1
RTECS: YE0175000
F: 34
Hazard Note: Highly Flammable/Corrosive
HazardClass: 3
PackingGroup: II
HS Code: 29211910

Product Name

Triethylamine

Synthetic route

Triethylamine Chemical Properties

Triethylamine Uses

Triethylamine Toxicity Data With Reference

Triethylamine Safety Profile

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