Trifluoromethyl iodide supplier

Name
Trifluoromethyl iodide
EINECS 219-014-5
CAS No. 2314-97-8
Article Data126
CAS DataBase
Density 2.44 g/cm³
Solubility Slightly soluble in water.
Melting Point <?78°C(lit.)
Formula CF₃I
Boiling Point -21.111 °C at 760 mmHg
Molecular Weight 195.911
Flash Point -26.936 °C
Transport Information UN 1956
Appearance colourless gas
Safety 36/37
Risk Codes 68
Molecular Structure
Hazard Symbols Xi,Xn
Synonyms Freon 13I1;Iodotrifluoromethane;Monoiodotrifluoromethane;Perfluoromethyl iodide;Trifluoroiodomethane;
PSA 0.00000
LogP 1.94120

Synthetic route

: 112425-78-2
S-(trifluoromethyl)diphenylsulfonium tetrafluoroborate

: 2314-97-8
iodotrifluoromethane

Conditions

Conditions	Yield
With sodium iodide In acetonitrile for 0.25h; Heating;	100%

: 2714-60-5
tetrakis(trifluoromethyl)diphosphine

: 2314-97-8
iodotrifluoromethane

Conditions

Conditions	Yield
With iodine byproducts: phophorus iodide; 280°C (48 h);	95%

: 421-83-0
trifluoromethane sulfonyl chloride

: 2314-97-8
iodotrifluoromethane

Conditions

Conditions	Yield
With sodium iodide In acetonitrile at 70℃; for 2h; Inert atmosphere;	86%
With dihydrogen peroxide; iodine monofluoride; bis(acetylacetonate)oxovanadium In water Product distribution / selectivity; Heating / reflux;	15%
With iodine monofluoride; palladium on activated carbon; copper on carbon; platinum on activated charcoal at 250 - 550℃; Product distribution / selectivity; Vapor phase;

: 432-02-0
tris(trifluoromethyl)arsine

: 7553-56-2
iodine

A: 2314-97-8
iodotrifluoromethane

B: 353-91-3
trifluoromethyl-arsonous acid diiodide

C: 359-55-7
iodo-bis-trifluoromethyl-arsine

D: 7784-45-4
arsenic triiodide

Conditions

Conditions	Yield
100°C, 48 h; at high temp. more AsI3 and CF3I;	A 80% B 5% C 8% D n/a
100°C, 48 h; at high temp. more AsI3 and CF3I;	A 80% B 5% C 8% D n/a

...Expand

: 1514-87-0
metyhyl chlorodifluoroacetate

A: 2314-97-8
iodotrifluoromethane

B: 124-38-9
carbon dioxide

C: 1184-76-5
difluorodiiodomethane

D: 74-88-4
methyl iodide

Conditions

Conditions	Yield
With potassium fluoride; copper(l) iodide; iodine In N,N-dimethyl-formamide at 120℃; for 3h; Mechanism; other bromodifluoroacetate deriv.; var. temp. and times of reaction;	A 77% B n/a C 10% D n/a

...Expand

: 1514-87-0
metyhyl chlorodifluoroacetate

A: 2314-97-8
iodotrifluoromethane

B: 1184-76-5
difluorodiiodomethane

C: 74-88-4
methyl iodide

Conditions

Conditions	Yield
With potassium fluoride; copper(l) iodide; iodine In N,N-dimethyl-formamide at 120℃; for 3h;	A 77% B 10% C n/a

...Expand

: 354-34-7
trifluoroacetyl fluoride

: 2314-97-8
iodotrifluoromethane

Conditions

Conditions	Yield
With lithium iodide at 180℃; for 7h;	73%

: 354-34-7
trifluoroacetyl fluoride

A: 2314-97-8
iodotrifluoromethane

B: 354-36-9
trifluoroacetyl iodide

Conditions

Conditions	Yield
With lithium iodide at 180℃; for 7h;	A 73% B 26%

: 683-98-7
methyl bromodifluoroacetate

A: 2314-97-8
iodotrifluoromethane

B: 74-88-4
methyl iodide

Conditions

Conditions	Yield
With potassium fluoride; copper(l) iodide; iodine In N,N-dimethyl-formamide at 80℃; for 5h;	A 70% B n/a

: 75-46-7
trifluoromethan

: 2314-97-8
iodotrifluoromethane

Conditions

Conditions	Yield
With hydrogen iodide; oxygen at 500℃; Product distribution / selectivity;	67%
With oxygen; iodine monofluoride at 550℃; Product distribution / selectivity;	40%
With iodine monofluoride at 550℃; Product distribution / selectivity;	40%

: 432-02-0
tris(trifluoromethyl)arsine

: 74-88-4
methyl iodide

A: 75-46-7
trifluoromethan

B: 2314-97-8
iodotrifluoromethane

C: 431-76-5
methylbistrifluoromethylarsine

D: 359-55-7
iodo-bis-trifluoromethyl-arsine

E: 57028-26-9
Trifluormethyl-methyl-iodarsin

Conditions

Conditions	Yield
235°C, 24 h; no formation of F3CCH3;	A n/a B 64% C n/a D n/a E n/a

...Expand

: 371-76-6
bis(trifluoromethyl)mercury

: 7790-44-5
antimony triiodide

A: 2314-97-8
iodotrifluoromethane

B: 432-05-3
tris(trifluoromethyl)stibane

C: 1479-46-5
Bis(trifluormethyl)-jodstiban

Conditions

Conditions	Yield
SbI3 and Hg(CF3)2 heated to 165°C for 8h; at -131°C sepd. (CF3)2SbI and Sb(CF3)3;	A n/a B 63% C 2%

...Expand

: 61110-81-4
dichloro-trifluoromethyl-λ3-iodane

: 2966-50-9
silver trifluoroacetate

A: 75-72-9
chlorotrifluoromethane

B: 2314-97-8
iodotrifluoromethane

C: 60669-28-5
Trifluoromethyliodine(III) bis-trifluoroacetate

Conditions

Conditions	Yield
In acetonitrile at -40℃;	A n/a B n/a C 56%

...Expand

: 432-04-2
tris(trifluoromethyl)phosphine

: 74-88-4
methyl iodide

A: 2314-97-8
iodotrifluoromethane

B: 1605-54-5
methyl-bis-trifluoromethyl-phosphine

Conditions

Conditions	Yield
240°C, 24 h;	A n/a B 54%

...Expand

: 432-05-3
tris(trifluoromethyl)stibane

A: 2314-97-8
iodotrifluoromethane

B: Trifluormethyl-dijodstiban

C: 1479-46-5
Bis(trifluormethyl)-jodstiban

Conditions

Conditions	Yield
With iodine shaking in sealed tube for 30 min;	A n/a B 14% C 54%
With I2 shaking in sealed tube for 30 min;	A n/a B 14% C 54%
With iodine room temp.;
With iodine room temp.;

...Expand

: 359-64-8
iodo-bis-trifluoromethyl-phosphine

A: 2314-97-8
iodotrifluoromethane

B: 76-16-4
Hexafluoroethane

C: 421-59-0
trifluoromethyldiiodophosphine

D: 432-04-2
tris(trifluoromethyl)phosphine

E: 13455-01-1
phosphorous triiodide

Conditions

Conditions	Yield
205°C (48 h);	A 2% B 8% C 2% D 45% E n/a

...Expand

: 421-59-0
trifluoromethyldiiodophosphine

A: 359-64-8
iodo-bis-trifluoromethyl-phosphine

B: 2314-97-8
iodotrifluoromethane

C: 432-04-2
tris(trifluoromethyl)phosphine

D: 13455-01-1
phosphorous triiodide

Conditions

Conditions	Yield
240°C (48 h);	A 41% B 13% C 23% D n/a
In neat (no solvent) heating to 240°C;;

...Expand

: 456-56-4
phenyl trifluoromethylsulfide

: 2314-97-8
iodotrifluoromethane

Conditions

Conditions	Yield
With dihydrogen peroxide; iodine monofluoride; bis(acetylacetonate)oxovanadium In water Product distribution / selectivity; Heating / reflux;	40%
With iodine heptafluoride; dihydrogen peroxide; bis(acetylacetonate)oxovanadium In water Product distribution / selectivity; Heating / reflux;	30%
With dihydrogen peroxide; iodine pentafluoride; bis(acetylacetonate)oxovanadium In water Product distribution / selectivity; Heating / reflux;	30%

: 372-64-5
Bis(trifluoromethyl)disulfid

: 2314-97-8
iodotrifluoromethane

Conditions

Conditions	Yield
With dihydrogen peroxide; iodine monofluoride; bis(acetylacetonate)oxovanadium In water Product distribution / selectivity; Heating / reflux;	40%
With iodine heptafluoride; dihydrogen peroxide; bis(acetylacetonate)oxovanadium In water Product distribution / selectivity; Heating / reflux;	30%
With dihydrogen peroxide; iodine pentafluoride; bis(acetylacetonate)oxovanadium In water Product distribution / selectivity; Heating / reflux;	30%

: 421-16-9
methyl trifluoromethyl sulphide

: 2314-97-8
iodotrifluoromethane

Conditions

Conditions	Yield
With dihydrogen peroxide; iodine monofluoride; bis(acetylacetonate)oxovanadium In water Product distribution / selectivity; Heating / reflux;	40%
With iodine heptafluoride; dihydrogen peroxide; bis(acetylacetonate)oxovanadium In water Product distribution / selectivity; Heating / reflux;	30%
With dihydrogen peroxide; iodine pentafluoride; bis(acetylacetonate)oxovanadium In water Product distribution / selectivity; Heating / reflux;	30%

: 1643-70-5
[(trifluoromethyl)disulfanyl]benzene

: 2314-97-8
iodotrifluoromethane

Conditions

Conditions	Yield
With dihydrogen peroxide; iodine monofluoride; bis(acetylacetonate)oxovanadium In water Product distribution / selectivity; Heating / reflux;	40%
With iodine heptafluoride; dihydrogen peroxide; bis(acetylacetonate)oxovanadium In water Product distribution / selectivity; Heating / reflux;	30%
With dihydrogen peroxide; iodine pentafluoride; bis(acetylacetonate)oxovanadium In water Product distribution / selectivity; Heating / reflux;	30%

: 14410-21-0
trifluoromethyl disulphide

: 2314-97-8
iodotrifluoromethane

Conditions

Conditions	Yield
With dihydrogen peroxide; iodine monofluoride; bis(acetylacetonate)oxovanadium In water Product distribution / selectivity; Heating / reflux;	40%
With iodine heptafluoride; dihydrogen peroxide; bis(acetylacetonate)oxovanadium In water Product distribution / selectivity; Heating / reflux;	30%
With dihydrogen peroxide; iodine pentafluoride; bis(acetylacetonate)oxovanadium In water Product distribution / selectivity; Heating / reflux;	30%

: 432-04-2
tris(trifluoromethyl)phosphine

: 7553-56-2
iodine

A: 359-64-8
iodo-bis-trifluoromethyl-phosphine

B: 2314-97-8
iodotrifluoromethane

C: 421-59-0
trifluoromethyldiiodophosphine

D: 13455-01-1
phosphorous triiodide

Conditions

Conditions	Yield
180°C, 24 h;	A 16% B 34% C 4% D n/a

...Expand

: 432-02-0
tris(trifluoromethyl)arsine

A: 2314-97-8
iodotrifluoromethane

B: 353-91-3
trifluoromethyl-arsonous acid diiodide

C: 359-55-7
iodo-bis-trifluoromethyl-arsine

Conditions

Conditions	Yield
100-105°C, 72 h;	A 28% B n/a C 22%

...Expand

: 75-63-8
Bromotrifluoromethane

: 2314-97-8
iodotrifluoromethane

Conditions

Conditions	Yield
With hydrogen; iodine monofluoride; 3 weight% Pd/C In dimethyl sulfoxide; N,N-dimethyl-formamide at 100℃; Product distribution / selectivity;	20%
With iodine monofluoride; zinc; 3 weight% Pd/C In dimethyl sulfoxide; N,N-dimethyl-formamide at 100℃; Product distribution / selectivity;	20%
With iodine Product distribution; Irradiation; thermal + multiple photon IR laser excitation; different laser energy fluence and temperatures;

: 432-02-0
tris(trifluoromethyl)arsine

: 74-88-4
methyl iodide

A: 2314-97-8
iodotrifluoromethane

B: 76-16-4
Hexafluoroethane

C: 431-76-5
methylbistrifluoromethylarsine

Conditions

Conditions	Yield
Irradiation (UV/VIS); with UV-light;	A 18% B 15% C n/a

...Expand

: 105062-51-9
CF13IO2Te2

A: 75-73-0
carbon tetrafluoride

B: 2314-97-8
iodotrifluoromethane

C: 105062-50-8
CF8OTe

D (TeF4O)n, I(OTeF5)3: (TeF4O)n, I(OTeF5)3

Conditions

Conditions	Yield
at 25℃; for 2h;	A n/a B n/a C 17% D n/a

...Expand

: 354-32-5
trifluoracetyl chloride

: 2314-97-8
iodotrifluoromethane

Conditions

Conditions	Yield
With dihydrogen peroxide; iodine monofluoride; bis(acetylacetonate)oxovanadium In water Product distribution / selectivity; Heating / reflux;	15%
With potassium iodide at 200℃;
With iodine monofluoride; palladium on activated carbon; copper on carbon; platinum on activated charcoal at 250 - 550℃; Product distribution / selectivity; Vapor phase;
With hydrogen iodide at 350℃; for 0.00555556h; Catalytic behavior; Reagent/catalyst;	65.19 %Chromat.
With 0.5% Pd/Al2O3; hydrogen; iodine at 150 - 350℃; Flow reactor;

: 81290-20-2
(trifluoromethyl)trimethylsilane

: 2314-97-8
iodotrifluoromethane

Conditions

Conditions	Yield
With dihydrogen peroxide; iodine monofluoride; bis(acetylacetonate)oxovanadium In water Product distribution / selectivity; Heating / reflux;	15%
With iodine; oxygen; palladium on activated charcoal at 350℃; Product distribution / selectivity;
With sulfuric acid; iodine; oxygen; bis(acetylacetonate)oxovanadium In Hexafluorobenzene at 30 - 150℃; for 12h; Product distribution / selectivity;
With iodine monofluoride; palladium on activated carbon; copper on carbon; platinum on activated charcoal at 250 - 550℃; Product distribution / selectivity; Vapor phase;

: 434-45-7
1,1,1-trifluoroacetophenone

: 2314-97-8
iodotrifluoromethane

Conditions

Conditions	Yield
With dihydrogen peroxide; iodine monofluoride; bis(acetylacetonate)oxovanadium In water Product distribution / selectivity; Heating / reflux;	15%
With iodine monofluoride; palladium on activated carbon; copper on carbon; platinum on activated charcoal at 250 - 550℃; Product distribution / selectivity; Vapor phase;

: 2314-97-8
iodotrifluoromethane

: 36525-64-1
perfluoro-NN'-dimethylethane-1,2-bis(amino-oxyl) diradical

: perfluoro-(3,6-dimethyl-2,7-dioxa-3,6-diaza-octane)

Conditions

Conditions	Yield
for 24h; Irradiation;	100%

: 2314-97-8
iodotrifluoromethane

: 373-68-2
tetramethylammonium fluoride

: 81290-20-2
(trifluoromethyl)trimethylsilane

: C4H12N(1+)*C2F6I(1-)

Conditions

Conditions	Yield
In tetrahydrofuran at -60℃; for 2h;	100%

...Expand

: 2645-22-9
bis(4-pyridyl) disulfide

: 2314-97-8
iodotrifluoromethane

: 4-((trifluoromethy)lthio)pyridine

Conditions

Conditions	Yield
With Tetrakis(dimethylamino)ethylen In N,N-dimethyl-formamide at 0 - 20℃; for 12h;	100%
With Tetrakis(dimethylamino)ethylen In N,N-dimethyl-formamide at 0 - 20℃;

: 1-iodo-4-isopropyl-2-methoxy-5-(toluene-4-sulfonyl)-benzene

: 2314-97-8
iodotrifluoromethane

: 865305-65-3
1-Isopropyl-5-methoxy-2-(toluene-4-sulfonyl)-4-trifluoromethyl-benzene

Conditions

Conditions	Yield
Stage #1: 1-iodo-4-isopropyl-2-methoxy-5-(toluene-4-sulfonyl)-benzene With potassium fluoride; copper(l) iodide In DMF (N,N-dimethyl-formamide) at 120℃; Stage #2: iodotrifluoromethane In DMF (N,N-dimethyl-formamide) for 4.5h;	100%
With potassium fluoride; copper(l) iodide In N,N-dimethyl-formamide at 20℃; for 4.5h;	100%

: 2314-97-8
iodotrifluoromethane

: 592-02-9
diethylcadmium

: 75-05-8
acetonitrile

: bis(trifluoromethyl)cadmium*2CH3CN

Conditions

Conditions	Yield
In acetonitrile byproducts: EtI; Ar-atmosphere; stirring (-23°C); evapn. (vac.);	100%

...Expand

: 1-iodo-4-isopropyl-2-methoxy-5-(toluene-4-sulfonyl)-benzene

: 2314-97-8
iodotrifluoromethane

: 1-isopropyl-5-methoxy-2-(toluene-4-sulfonyl)-4-trifluoromethyl-benzene

Conditions

Conditions	Yield
With potassium fluoride; copper(l) iodide In N,N-dimethyl-formamide at 120℃; for 4h;	100%
With potassium fluoride; copper(l) iodide In N,N-dimethyl-formamide at 120℃; for 4.5h;	100%

: 2314-97-8
iodotrifluoromethane

: 2-bromo-3-fluoro-6-mercaptobenzonitrile

: 2-bromo-3-fluoro-6-((trifluoromethyl)thio)benzonitrile

Conditions

Conditions	Yield
With paraquat dichloride; triethylamine In N,N-dimethyl-formamide at -78 - 20℃; for 18h; Sealed tube;	100%

: 2314-97-8
iodotrifluoromethane

: 110-18-9
N,N,N,N,-tetramethylethylenediamine

: 2CF3I*C6H16N2

Conditions

Conditions	Yield
at -78℃; for 0.333333h; Schlenk technique; Inert atmosphere; Reflux;	100%
at -78℃; for 0.333333h; Inert atmosphere; Reflux;	100%

: 2314-97-8
iodotrifluoromethane

: 80-70-6
N,N,N',N'-tetramethylguanidine

: TMG•CF3I

Conditions

Conditions	Yield
at -78 - 23℃; Schlenk technique; Inert atmosphere;	100%
at -78 - 23℃; Inert atmosphere;	100%

: 2314-97-8
iodotrifluoromethane

: 67-68-5
dimethyl sulfoxide

: Ritter's trifluoroiodomethane-DMSO complex

Conditions

Conditions	Yield
at -78 - 23℃; Schlenk technique; Inert atmosphere;	100%
at -78 - 23℃; Inert atmosphere;	100%
at -78℃;

: 2314-97-8
iodotrifluoromethane

: 2,4-dichloro-3-methyl-benzenethiol

: 1,3-dichloro-2-methyl-4-(trifluoromethylsulfanyl)benzene

Conditions

Conditions	Yield
With paraquat dichloride; triethylamine In N,N-dimethyl-formamide at -78 - 20℃; for 24h;	99.6%

: 2314-97-8
iodotrifluoromethane

: 1666-13-3
diphenyl diselenide

: 5173-02-4
phenyl trifluoromethylselenide

Conditions

Conditions	Yield
With Tetrakis(dimethylamino)ethylen In N,N-dimethyl-formamide at 0 - 20℃;	99%
With rongalite In water; N,N-dimethyl-formamide at 20℃;	28%
With Tetrakis(dimethylamino)ethylen In N,N-dimethyl-formamide at 0 - 20℃;

: 2314-97-8
iodotrifluoromethane

: 592-02-9
diethylcadmium

: 33327-66-1
bis(trifluoromethyl)cadmium

Conditions

Conditions	Yield
In chloroform byproducts: EtI; 2.5 equiv. CF3I, -40°C, 10 min (pptn.); removal of volatiles (vac.);	99%
In not given absence of air and moisture; in presence of 1 equiv. HCF2I;

: methyl(triphenylphosphine)gold(I)

: 2314-97-8
iodotrifluoromethane

: 60898-04-6
triluoromethyl(triphenylphosphine)gold(I)

Conditions

Conditions	Yield
In dichloromethane byproducts: MeI; 4 equiv. of CF3I, standing in sealed tube at 35°C for 45 min; evapn.; elem. anal.;	99%

: 2314-97-8
iodotrifluoromethane

: 73894-44-7
1-(8-Bromo-7-methoxy-1-phenyl-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-2,2,2-trifluoro-ethanone

: 73894-49-2
2,2,2-Trifluoro-1-(7-methoxy-1-phenyl-8-trifluoromethyl-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-ethanone

Conditions

Conditions	Yield
With copper In N,N-dimethyl-formamide at 150℃;	98%

: 2314-97-8
iodotrifluoromethane

: 73894-46-9
1-(8-Bromo-6-chloro-7-methoxy-1-phenyl-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-2,2,2-trifluoro-ethanone

: 73894-50-5
1-(6-Chloro-7-methoxy-1-phenyl-8-trifluoromethyl-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-2,2,2-trifluoro-ethanone

Conditions

Conditions	Yield
With copper In N,N-dimethyl-formamide at 150℃;	98%

: 2314-97-8
iodotrifluoromethane

: 78-27-3
1-Ethynyl-1-cyclohexanol

: 1579233-92-3
C9H13F3O

Conditions

Conditions	Yield
With fac-tris(2-phenylpyridinato-N,C2')iridium(III); 1,8-diazabicyclo[5.4.0]undec-7-ene In tetrahydrofuran; acetonitrile at 20℃; Sealed tube; Inert atmosphere; Irradiation; diastereoselective reaction;	98%

: 2314-97-8
iodotrifluoromethane

: 872-05-9
1-Decene

: 1,1,1-trifluoro-3-iodoundecane

Conditions

Conditions	Yield
With pyrrolidine; Diphenylacetaldehyde In dichloromethane at 20℃; for 16h; Inert atmosphere; Irradiation;	98%
With Eosin Y; sodium thiosulfate In acetonitrile at 20℃; for 1h; Inert atmosphere; Irradiation;	53%

: 2314-97-8
iodotrifluoromethane

: 111-66-0
oct-1-ene

: C9H15F3

Conditions

Conditions	Yield
With 5,10-di(4-trifluoromethylphenyl)-5,10-dihydrophenazine; potassium formate In N,N-dimethyl acetamide at 40℃; for 6h; Irradiation;	98%

: 2314-97-8
iodotrifluoromethane

: but-3-en-1-yl 4-chlorobenzoate

: 5,5,5-trifluoro-3-hydroxypentyl 4-chlorobenzoate

Conditions

Conditions	Yield
With N,N,N,N,-tetramethylethylenediamine In dimethyl sulfoxide at 20℃; for 36h; Schlenk technique; Irradiation;	98%

: 112-41-4
1-dodecene

: 2314-97-8
iodotrifluoromethane

: (E)-1,1,1-trifluorotridec-2-ene

Conditions

Conditions	Yield
With platinum(II) (2-phenylpyridinato-N,C(2'))(2,4-pentanedionato-O,O); 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile at 20℃; for 6h; Quantum yield; Sealed tube; Irradiation; Inert atmosphere;	97%
With tris(1,10-phenanthroline)ruthenium(II) dichloride; 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile for 2h; Solvent; Inert atmosphere;	96%
With tris(1,10-phenanthroline)ruthenium(II) dichloride; 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile at 20℃; Inert atmosphere; Irradiation; regioselective reaction;	95%
With 1,8-diazabicyclo[5.4.0]undec-7-ene; tri-(9-anthryl)borane In acetonitrile at 20℃; for 3h; Reagent/catalyst; Solvent; Wavelength; Inert atmosphere; Irradiation;	93%

: 2314-97-8
iodotrifluoromethane

: C19H23NO5S2

: 3-(2,4-dimethoxyphenyl)-4-tosyl-5-[(trifluoromethyl)thio]morpholine

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; eosin y In N,N-dimethyl-formamide at 20℃; for 0.5h; Reagent/catalyst; Concentration; Solvent; Time; Inert atmosphere; Irradiation;	97%

: 2314-97-8
iodotrifluoromethane

: hex-5-en-1-yl 4-iodobenzoate

: 7,7,7-trifluoro-5-hydroxyheptyl 4-iodobenzoate

Conditions

Conditions	Yield
With N,N,N,N,-tetramethylethylenediamine In dimethyl sulfoxide at 20℃; for 36h; Schlenk technique; Irradiation;	97%

: 695-12-5
vinylcyclohexane

: 2314-97-8
iodotrifluoromethane

: C9H13F3

Conditions

Conditions	Yield
With (dppf)Ni(o-tol)Cl; sodium t-butanolate In Hexafluorobenzene at 50℃; for 16h; Inert atmosphere; Schlenk technique; Sealed tube;	97%

: 2314-97-8
iodotrifluoromethane

: 74465-47-7
(2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-bromo-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate

: 76513-94-5
(2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-(trifluoromethyl)-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate

Conditions

Conditions	Yield
With copper(l) iodide; zinc In N,N-dimethyl-formamide at 70℃; for 10h;	96%

: 2314-97-8
iodotrifluoromethane

: 223463-13-6
2-iodo-5-bromopyridine

: 7440-66-6
zinc

: 436799-32-5
5-bromo-2(trifluoromethyl)pyridine

Conditions

Conditions	Yield
Stage #1: iodotrifluoromethane; zinc With 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone at 20℃; for 2h; Inert atmosphere; Stage #2: 2-iodo-5-bromopyridine With copper(l) iodide at 50℃; for 24h; Catalytic behavior; Reagent/catalyst; Inert atmosphere; chemoselective reaction;	96%

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: 2314-97-8
iodotrifluoromethane

: C11H20O3

: C12H19F3O3

Conditions

Conditions	Yield
With platinum(II) (2-phenylpyridinato-N,C(2'))(2,4-pentanedionato-O,O); 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile at 20℃; Sealed tube; Irradiation; Inert atmosphere;	96%

: 2314-97-8
iodotrifluoromethane

: C18H21NO4S2

: 3-(4-methoxyphenyl)-4-tosyl-5-[(trifluoromethyl)thio]morpholine

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; eosin y In N,N-dimethyl-formamide at 20℃; for 0.5h; Inert atmosphere; Irradiation;	96%

: 2314-97-8
iodotrifluoromethane

: C19H23NO3S2

: 3-(2,4-dimethylphenyl)-4-tosyl-5-[(trifluoromethyl)thio]morpholine

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; eosin y In N,N-dimethyl-formamide at 20℃; for 0.5h; Inert atmosphere; Irradiation;	96%

Trifluoromethyl iodide Specification

The Trifluoromethyl iodide, with the CAS registry number 2314-97-8 and EINECS registry number 219-014-5, has the systematic name of trifluoro(iodo)methane. And the molecular formula of this chemical is CF₃I. It is a kind of colourless gas, and very stable in normal condition.

The physical properties of Trifluoromethyl iodide are as following: (1)ACD/LogP: 2.25; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.24; (4)ACD/LogD (pH 7.4): 2.24; (5)ACD/BCF (pH 5.5): 29.93; (6)ACD/BCF (pH 7.4): 29.93; (7)ACD/KOC (pH 5.5): 396.47; (8)ACD/KOC (pH 7.4): 396.47; (9)#H bond acceptors: 0; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 0 Å²; (13)Index of Refraction: 1.415; (14)Molar Refractivity: 20.1 cm³; (15)Molar Volume: 80.2 cm³; (16)Polarizability: 7.97×10^-24cm³; (17)Surface Tension: 19.9 dyne/cm; (18)Density: 2.44 g/cm³; (19)Enthalpy of Vaporization: 22.18 kJ/mol; (20)Boiling Point: °C at 760 mmHg; (21)Vapour Pressure: 3650 mmHg at 25°C.

Preparation and uses of Trifluoromethyl iodide: It can be prepared by heating the silver salt of trifluoroacetic acid (TFA) and iodine. And it is a important reagent to take the triflouro to the molecule. It can react with organometallic compounds and ethylenic linkage compounds.

You should be cautious while dealing with this chemical. It may cause irreversible effects. Therefore, you had betterwear suitable protective clothing and gloves.

You can still convert the following datas into molecular structure:
(1)SMILES: FC(F)(F)I
(2)InChI: InChI=1/CF3I/c2-1(3,4)5
(3)InChIKey: VPAYJEUHKVESSD-UHFFFAOYAR

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
rat	LCLo	inhalation	1pph/4H (10000ppm)		Fundamental and Applied Toxicology. Vol. 35, Pg. 64, 1997.

Product Name

Trifluoromethyl iodide

Synthetic route

Trifluoromethyl iodide Specification

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