TRIMETHYLSILYL METHANESULFONATE

The systematic name of this chemical is trimethylsilyl methanesulfonate. With the CAS registry number 10090-05-8 and EINECS 233-220-2, it is also named as Silanol, trimethyl-, methanesulfonate. The product's categories are Protecting and Derivatizing Reagents; Protection and Derivatization; Silicon-Based. It is dark yllow liquid which should be sealed in the container and stored in the cool and dry place.

The other characteristics of this product can be summarized as: (1)ACD/LogP: 1.01; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.01; (4)ACD/LogD (pH 7.4): 1.01; (5)ACD/BCF (pH 5.5): 3.46; (6)ACD/BCF (pH 7.4): 3.46; (7)ACD/KOC (pH 5.5): 84.69; (8)ACD/KOC (pH 7.4): 84.69; (9)#H bond acceptors: 3; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 2; (12)Index of Refraction: 1.419; (13)Molar Refractivity: 39.87 cm³; (14)Molar Volume: 157.6 cm³; (15)Polarizability: 15.8×10^-24 cm³; (16)Surface Tension: 25.1 dyne/cm; (17)Enthalpy of Vaporization: 42.79 kJ/mol; (18)Vapour Pressure: 0.287 mmHg at 25°C.

Preparation of Trimethylsilyl methanesulfonate: It can be obtained by methanesulfonic acid methyl ester and bromo-trimethyl-silane. This reaction needs heating for 6 hours. The yield is 96.5%.

Uses of Trimethylsilyl methanesulfonate: It can react with methylsulfanyl-acetonitrile to get cyano(methylthio)methyltrimethylsilane. This reaction needs reagent Et₃N and solvent diethyl ether at temperature of 0-5 °C. The reaction time is 3 hours. The yield is 85%.

When you are using this chemical, please be cautious about it as the following:
It is flammable. When use it, people should not breathe vapour and avoid contact with skin and eyes.

People can use the following data to convert to the molecule structure. 
1. SMILES:O=S(=O)(O[Si](C)(C)C)C
2. InChI:InChI=1/C4H12O3SSi/c1-8(5,6)7-9(2,3)4/h1-4H3
3. InChIKey:BCHASIUOFGDRIO-UHFFFAOYAY