Product Name

  • Name

    N,N-Dipropyl-1-propanamine

  • EINECS 203-047-7
  • CAS No. 102-69-2
  • Article Data50
  • CAS DataBase
  • Density 0.777 g/cm3
  • Solubility 2.6 g/L (20 °C) in water
  • Melting Point -93.5 °C(lit.)
  • Formula C9H21N
  • Boiling Point 158.1 °C at 760 mmHg
  • Molecular Weight 143.272
  • Flash Point 36.7 °C
  • Transport Information UN 2260 3/PG 3
  • Appearance colourless liquid
  • Safety 26-36/37/39-45-16
  • Risk Codes 10-20/21-25-34-52/53-23/25-21
  • Molecular Structure Molecular Structure of 102-69-2 (N,N-Dipropyl-1-propanamine)
  • Hazard Symbols ToxicT
  • Synonyms Tripropylamine(6CI,8CI);N,N-Dipropyl-1-propanamine;Propyldi-n-propylamine;Tri-n-propylamine;
  • PSA 3.24000
  • LogP 2.51840

Synthetic route

ethene
74-85-1

ethene

carbon monoxide
201230-82-2

carbon monoxide

di-n-propylamine
142-84-7

di-n-propylamine

tri-n-propylamine
102-69-2

tri-n-propylamine

Conditions
ConditionsYield
di(rhodium)tetracarbonyl dichloride In ethanol at 115℃; under 37503 Torr; for 1.5h;100%
propylamine
107-10-8

propylamine

ethene
74-85-1

ethene

carbon monoxide
201230-82-2

carbon monoxide

A

tri-n-propylamine
102-69-2

tri-n-propylamine

B

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
di(rhodium)tetracarbonyl dichloride In ethanol at 119℃; under 44253.5 Torr; for 1h;A 1%
B 99%
di(rhodium)tetracarbonyl dichloride In ethanol at 119℃; under 44253.5 Torr; for 1h;A 2%
B 98%
propan-1-ol
71-23-8

propan-1-ol

octanol
111-87-5

octanol

propiononitrile
107-12-0

propiononitrile

A

tri-n-propylamine
102-69-2

tri-n-propylamine

B

Dipropyloctylamin
99209-95-7

Dipropyloctylamin

Conditions
ConditionsYield
With hydrogen; copper at 240℃; under 7600 Torr;A n/a
B 95%
propan-1-ol
71-23-8

propan-1-ol

propiononitrile
107-12-0

propiononitrile

nonyl alcohol
143-08-8

nonyl alcohol

A

tri-n-propylamine
102-69-2

tri-n-propylamine

B

N,N-dipropylnonylamine

N,N-dipropylnonylamine

Conditions
ConditionsYield
With hydrogen; copper at 240℃; under 7600 Torr;A n/a
B 90%
propiononitrile
107-12-0

propiononitrile

A

tri-n-propylamine
102-69-2

tri-n-propylamine

B

N-propylidenepropylamine
7707-70-2

N-propylidenepropylamine

C

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
With hydrogen at 220℃;A 8.5%
B 2.5%
C 89%
With hydrogen at 240℃; Temperature; Flow reactor;A 13%
B 2.5%
C 80%
propan-1-ol
71-23-8

propan-1-ol

1-Decanol
112-30-1

1-Decanol

propiononitrile
107-12-0

propiononitrile

A

tri-n-propylamine
102-69-2

tri-n-propylamine

B

N,N-dipropyldecylamine
88090-10-2

N,N-dipropyldecylamine

Conditions
ConditionsYield
With hydrogen; copper at 240℃; under 7600 Torr;A n/a
B 86%
propan-1-ol
71-23-8

propan-1-ol

undecyl alcohol
112-42-5

undecyl alcohol

propiononitrile
107-12-0

propiononitrile

A

tri-n-propylamine
102-69-2

tri-n-propylamine

B

N,N-dipropylundecylamine

N,N-dipropylundecylamine

Conditions
ConditionsYield
With hydrogen; copper at 240℃; under 7600 Torr;A n/a
B 80%
propan-1-ol
71-23-8

propan-1-ol

1-dodecyl alcohol
112-53-8

1-dodecyl alcohol

propiononitrile
107-12-0

propiononitrile

A

tri-n-propylamine
102-69-2

tri-n-propylamine

B

N,N-Dipropyl-dodecyl amine
30427-39-5

N,N-Dipropyl-dodecyl amine

Conditions
ConditionsYield
With hydrogen; copper at 240℃; under 7600 Torr;A n/a
B 80%
propan-1-ol
71-23-8

propan-1-ol

1-Tetradecanol
112-72-1

1-Tetradecanol

propiononitrile
107-12-0

propiononitrile

A

tri-n-propylamine
102-69-2

tri-n-propylamine

B

N,N-dipropyl-tetradecylamine

N,N-dipropyl-tetradecylamine

Conditions
ConditionsYield
With hydrogen; copper at 240℃; under 7600 Torr;A n/a
B 76%
propan-1-ol
71-23-8

propan-1-ol

pentadecanol
629-76-5

pentadecanol

propiononitrile
107-12-0

propiononitrile

A

tri-n-propylamine
102-69-2

tri-n-propylamine

B

N,N-dipropylpentadecylamine

N,N-dipropylpentadecylamine

Conditions
ConditionsYield
With hydrogen; copper at 240℃; under 7600 Torr;A n/a
B 75%
propan-1-ol
71-23-8

propan-1-ol

tridecan-1-ol
112-70-9

tridecan-1-ol

propiononitrile
107-12-0

propiononitrile

A

tri-n-propylamine
102-69-2

tri-n-propylamine

B

Di-n-propyl-n-tridecylamin

Di-n-propyl-n-tridecylamin

Conditions
ConditionsYield
With hydrogen; copper at 240℃; under 7600 Torr;A n/a
B 75%
propan-1-ol
71-23-8

propan-1-ol

1-Hexadecanol
36653-82-4

1-Hexadecanol

propiononitrile
107-12-0

propiononitrile

A

tri-n-propylamine
102-69-2

tri-n-propylamine

B

N,N-dipropylhexadecylamine
35902-86-4

N,N-dipropylhexadecylamine

Conditions
ConditionsYield
With hydrogen; copper at 240℃; under 7600 Torr;A n/a
B 75%
1-Nitropropane
108-03-2

1-Nitropropane

A

propan-1-ol
71-23-8

propan-1-ol

B

tri-n-propylamine
102-69-2

tri-n-propylamine

C

propiononitrile
107-12-0

propiononitrile

Conditions
ConditionsYield
With carbon monoxide; water; hexarhodium hexadecacarbonyl In 2-ethoxy-ethanol at 40℃; under 12160 Torr; for 48h; Product distribution; other N-O compounds, effect of catalysts: Rh6(CO)16-amine polymers, -(CH3)2N(CH2)3N(CH3)2, (CH3)3N, (C3H7)3N;A 19%
B 4%
C 72%
With carbon monoxide; water; hexarhodium hexadecacarbonyl In 2-ethoxy-ethanol at 40℃; under 12160 Torr; for 48h;A 19%
B 4%
C 72%
With carbon monoxide; water; hexarhodium hexadecacarbonyl In 2-ethoxy-ethanol at 40℃; under 12160 Torr; for 48h;A 32%
B 3%
C 55%
With carbon monoxide; (CH3)2NC3H6NH-substituted polystyrene; water; hexarhodium hexadecacarbonyl In 2-ethoxy-ethanol at 40℃; under 12160 Torr; for 48h; Title compound not separated from byproducts;A 19 % Chromat.
B 3 % Chromat.
C 72 % Chromat.
di-n-propylamine
142-84-7

di-n-propylamine

A

propylamine
107-10-8

propylamine

B

tri-n-propylamine
102-69-2

tri-n-propylamine

Conditions
ConditionsYield
With hydrogen; Cu/Co/Ni/gamma-Al2O3 catalyst at 220℃; under 63756.4 Torr; Product distribution / selectivity;A 4%
B 49%
1-Nitropropane
108-03-2

1-Nitropropane

A

propan-1-ol
71-23-8

propan-1-ol

B

tri-n-propylamine
102-69-2

tri-n-propylamine

C

n-hexan-3-one
589-38-8

n-hexan-3-one

D

propiononitrile
107-12-0

propiononitrile

Conditions
ConditionsYield
With carbon monoxide; water; hexarhodium hexadecacarbonyl; trimethylamine In 2-ethoxy-ethanol at 40℃; under 12160 Torr; for 24h;A 16%
B 8%
C 7%
D 40%
With carbon monoxide; water; hexarhodium hexadecacarbonyl In 2-ethoxy-ethanol at 40℃; under 12160 Torr; for 48h;A 7%
B 4%
C 18%
D 31%
With N,N,N'N'-tetramethyl-1,3-propanediamine; carbon monoxide; water; hexarhodium hexadecacarbonyl In 2-ethoxy-ethanol at 40℃; under 12160 Torr; for 24h; Product distribution; Mechanism; aminosubstituded polystyrenes or other amines instead of TMPDA, other solvents, recycling of polystyrene-bound Rh-cluster complex;A 15 % Chromat.
B 4 % Chromat.
C 0 % Chromat.
D 71 % Chromat.
With carbon monoxide; amino-substituted polystyrene; water; hexarhodium hexadecacarbonyl In 2-ethoxy-ethanol at 40℃; under 12160 Torr; for 48h; Title compound not separated from byproducts;A 7 % Chromat.
B 4 % Chromat.
C 18 % Chromat.
D 31 % Chromat.
propan-1-ol
71-23-8

propan-1-ol

tri-n-propylamine
102-69-2

tri-n-propylamine

Conditions
ConditionsYield
With phosphoric acid; ammonia at 250 - 500℃;
propionaldehyde oxime
627-39-4

propionaldehyde oxime

tri-n-propylamine
102-69-2

tri-n-propylamine

Conditions
ConditionsYield
With ammonia; platinum under 2280 Torr; Hydrogenation;
With water; palladium under 2280 Torr; Hydrogenation;

A

tri-n-propylamine
102-69-2

tri-n-propylamine

B

propene
187737-37-7

propene

Conditions
ConditionsYield
With water durch Destillation;
tripropylamine oxide
22709-48-4

tripropylamine oxide

tri-n-propylamine
102-69-2

tri-n-propylamine

Conditions
ConditionsYield
With sulfur dioxide; water
With N,N,N'N'-tetramethyl-1,3-propanediamine; carbon monoxide; water; hexarhodium hexadecacarbonyl In 2-ethoxy-ethanol at 40℃; under 6080 Torr; for 24h;91 % Chromat.
With N,N,N'N'-tetramethyl-1,3-propanediamine; carbon monoxide; water; hexarhodium hexadecacarbonyl In 2-ethoxy-ethanol at 40℃; under 6080 Torr; for 24h; Product distribution; Mechanism; (CH3)2NC3H6NH-substituted polystyrene instead of TMPDA; analogous reaction of another amine oxide;91 % Chromat.
tripropylamine oxide
22709-48-4

tripropylamine oxide

A

tri-n-propylamine
102-69-2

tri-n-propylamine

B

propene
187737-37-7

propene

C

N,N-di-n-propylhydroxylamine
7446-43-7

N,N-di-n-propylhydroxylamine

Conditions
ConditionsYield
beim Erhitzen unter gewoenlichem Druck;
propylamine
107-10-8

propylamine

propionaldehyde
123-38-6

propionaldehyde

tri-n-propylamine
102-69-2

tri-n-propylamine

Conditions
ConditionsYield
With nickel at 162 - 195℃; under 36775.4 - 73550.8 Torr; Hydrogenation;
propionaldehyde
123-38-6

propionaldehyde

tri-n-propylamine
102-69-2

tri-n-propylamine

Conditions
ConditionsYield
With ammonia; platinum under 2280 Torr; Hydrogenation;
propiononitrile
107-12-0

propiononitrile

tri-n-propylamine
102-69-2

tri-n-propylamine

Conditions
ConditionsYield
With platinum under 2280 Torr; Hydrogenation;
With 5%-palladium/activated carbon; ammonium formate In hexane at 20℃;
With hydrogen at 70℃; under 750.075 Torr; for 6h; chemoselective reaction;
tributyl-amine
102-82-9

tributyl-amine

tri(n-propyl)amine-H+
50985-90-5

tri(n-propyl)amine-H+

A

tri-n-propylamine
102-69-2

tri-n-propylamine

B

tributylammonium
19497-26-8

tributylammonium

Conditions
ConditionsYield
at 176.9℃; Rate constant; Thermodynamic data; Kinetics; var. temp.; ΔH0, ΔS0;
propionaldehyde
123-38-6

propionaldehyde

A

propylamine
107-10-8

propylamine

B

tri-n-propylamine
102-69-2

tri-n-propylamine

C

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
With ammonia; hydrogen; 20% Ni/Al2O3; nickel at 180℃; Product distribution; influence of nature of the catalyst and temperature;A 49.7 mol
B 2.8 mol
C 44.3 mol
1-phenylethyltripropylammonium bromide
124188-41-6

1-phenylethyltripropylammonium bromide

A

styrene
292638-84-7

styrene

B

tri-n-propylamine
102-69-2

tri-n-propylamine

Conditions
ConditionsYield
With sodium ethanolate In ethanol at 60℃; Rate constant; Mechanism;
1-phenylethyltripropylammonium-2,2,2-d3 bromide
124188-52-9

1-phenylethyltripropylammonium-2,2,2-d3 bromide

A

tri-n-propylamine
102-69-2

tri-n-propylamine

B

styrene-d2
934-85-0

styrene-d2

Conditions
ConditionsYield
With sodium ethanolate In ethanol at 60℃; Rate constant; Mechanism; hydrogen-deuterium isotop effect;
propylamine
107-10-8

propylamine

A

tri-n-propylamine
102-69-2

tri-n-propylamine

B

isocapronitrile
542-54-1

isocapronitrile

C

N-propylidenepropylamine
7707-70-2

N-propylidenepropylamine

D

di-n-propylamine
142-84-7

di-n-propylamine

E

propiononitrile
107-12-0

propiononitrile

Conditions
ConditionsYield
Cu-MFI/VIE In gas at 299.85℃; for 2h; Product distribution; other catalysts; var. reaction times;
ammonia
7664-41-7

ammonia

propionaldehyde
123-38-6

propionaldehyde

platinum

platinum

tri-n-propylamine
102-69-2

tri-n-propylamine

Conditions
ConditionsYield
at 25℃; unter 3 Atm. Wasserstoff-Ueberdruck.Hydrogenation;
water
7732-18-5

water

propiononitrile
107-12-0

propiononitrile

platinum

platinum

tri-n-propylamine
102-69-2

tri-n-propylamine

Conditions
ConditionsYield
at 25℃; under 2280 Torr; Hydrogenation;
1,3-propanesultone
1120-71-4

1,3-propanesultone

tri-n-propylamine
102-69-2

tri-n-propylamine

C12H27NO3S

C12H27NO3S

Conditions
ConditionsYield
In acetonitrile for 24h; Reflux;100%
In 1,2-dichloro-ethane at 30℃; for 6h;98%
tri-n-propylamine
102-69-2

tri-n-propylamine

phosphoric acid
86119-84-8, 7664-38-2

phosphoric acid

vanadia

vanadia

5.12V(3+)*4PO4(3-)*3.36OH(1-)*1.48H2O=V5.12(PO4)4(OH)3.36(H2O)0.64*0.84H2O

5.12V(3+)*4PO4(3-)*3.36OH(1-)*1.48H2O=V5.12(PO4)4(OH)3.36(H2O)0.64*0.84H2O

Conditions
ConditionsYield
In water High Pressure; hydrothermal synthesis; V2O5/H3PO4/amine/H2O=1:7:>10:1400, heating for 10 d at 200°C; washing (H2O), drying in air;99%
tri-n-propylamine
102-69-2

tri-n-propylamine

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

2,4,6-tris-(N,N-dipropylamino)-1,3,5-triazine
38565-82-1

2,4,6-tris-(N,N-dipropylamino)-1,3,5-triazine

Conditions
ConditionsYield
In dichloromethane at 0℃;98%
tri-n-propylamine
102-69-2

tri-n-propylamine

1,3-benzoxazol-2-amine
4570-41-6

1,3-benzoxazol-2-amine

N-propylaniline
622-80-0

N-propylaniline

Conditions
ConditionsYield
With hydrogenchloride; [Cp*IrCl(C5H4CH2C5H3OH)][Cl] In methanol at 120℃; for 12h; Schlenk technique;96%
tri-n-propylamine
102-69-2

tri-n-propylamine

2-chlorobenzo[d][1,3]thiazole
615-20-3

2-chlorobenzo[d][1,3]thiazole

N,N-dipropylbenzo[d]thiazol-2-amine
134126-35-5

N,N-dipropylbenzo[d]thiazol-2-amine

Conditions
ConditionsYield
at 100℃; under 6000480 Torr; for 96h;95%
tri-n-propylamine
102-69-2

tri-n-propylamine

1,1,1-trifluoro-4-(2-thienyl)butane-2,4-dione
326-91-0

1,1,1-trifluoro-4-(2-thienyl)butane-2,4-dione

4,4,4-trifluoro-1-thiophen-2-yl-butane-1,3-dione; compound with tripropyl-amine

4,4,4-trifluoro-1-thiophen-2-yl-butane-1,3-dione; compound with tripropyl-amine

Conditions
ConditionsYield
In acetonitrile at 25℃; for 24h;95%
tri-n-propylamine
102-69-2

tri-n-propylamine

2-chloro-4,6-dimethoxy-1 ,3,5-triazine
3140-73-6

2-chloro-4,6-dimethoxy-1 ,3,5-triazine

2,4-dimethoxy-6-(di-n-propylamino)-1,3,5-triazine
701229-89-2

2,4-dimethoxy-6-(di-n-propylamino)-1,3,5-triazine

Conditions
ConditionsYield
In toluene Reflux;95%
tri-n-propylamine
102-69-2

tri-n-propylamine

1 ,6-dibromohexane
629-03-8

1 ,6-dibromohexane

N1,N1,N1,N6,N6,N6-hexapropylhexane-1,6-diaminium dibromide

N1,N1,N1,N6,N6,N6-hexapropylhexane-1,6-diaminium dibromide

Conditions
ConditionsYield
In ethanol Reflux; Inert atmosphere;95%
In acetone for 24h; Reflux;
tri-n-propylamine
102-69-2

tri-n-propylamine

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

N1,N1,N1,N3,N3,N3-hexapropylpropane-1,3-diaminium dibromide

N1,N1,N1,N3,N3,N3-hexapropylpropane-1,3-diaminium dibromide

Conditions
ConditionsYield
In ethanol Reflux; Inert atmosphere;95%
2,3-dimethyl-6,7-dihydro-5H-2a-thia-(2a-SIV)-2,3,4a,7a-tetraazacyclopentindene-1,4(2H,3H)-dithione
72885-84-8

2,3-dimethyl-6,7-dihydro-5H-2a-thia-(2a-SIV)-2,3,4a,7a-tetraazacyclopentindene-1,4(2H,3H)-dithione

tri-n-propylamine
102-69-2

tri-n-propylamine

3-Methyl-1,1-dipropyl-thiourea
32900-03-1

3-Methyl-1,1-dipropyl-thiourea

Conditions
ConditionsYield
In benzene for 24h; Irradiation;94%
tri-n-propylamine
102-69-2

tri-n-propylamine

p-toluidine
106-49-0

p-toluidine

N-propyl-p-tolylamine
54837-90-0

N-propyl-p-tolylamine

Conditions
ConditionsYield
With palladium 10% on activated carbon In toluene at 175℃; for 1.5h; Inert atmosphere; Microwave irradiation;94%
tri-n-propylamine
102-69-2

tri-n-propylamine

aniline
62-53-3

aniline

N-propylaniline
622-80-0

N-propylaniline

Conditions
ConditionsYield
With palladium 10% on activated carbon In toluene at 175℃; for 1.5h; Inert atmosphere;94%
tri-n-propylamine
102-69-2

tri-n-propylamine

4-toluenesulfonyl azide
941-55-9

4-toluenesulfonyl azide

(E)-N'-((4-methylphenyl)sulfonyl)-N,N-dipropylformimidamide
1204768-66-0

(E)-N'-((4-methylphenyl)sulfonyl)-N,N-dipropylformimidamide

Conditions
ConditionsYield
With tert-butylammonium hexafluorophosphate(V) In acetonitrile at 25℃; for 3h; Electrolysis;94%
With 10-phenyl-9-(2,4,6-trimethylphenyl)acridinium tetrafluoroborate In 1,2-dichloro-ethane at 20℃; for 10h; Irradiation;85%
With tert.-butylhydroperoxide In water; 1,2-dichloro-ethane at 80℃; for 8h;80%
tri-n-propylamine
102-69-2

tri-n-propylamine

sodium cyanide
773837-37-9

sodium cyanide

2-(dipropylamino)butanenitrile
114583-14-1

2-(dipropylamino)butanenitrile

Conditions
ConditionsYield
With [4,4’-bis(1,1-dimethylethyl)-2,2’-bipyridine-N1,N1‘]bis [3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-N]phenyl-C]iridium(III) hexafluorophosphate; acetic acid In acetonitrile at 20℃; for 24h; Irradiation; Sealed tube;94%
tri-n-propylamine
102-69-2

tri-n-propylamine

C5H5FeC5H3CH3CH2N(CH3)3(1+)*I(1-)=[C5H5FeC5H3CH3CH2N(CH3)3]I
73543-65-4, 12111-93-2, 125949-07-7

C5H5FeC5H3CH3CH2N(CH3)3(1+)*I(1-)=[C5H5FeC5H3CH3CH2N(CH3)3]I

C5H5FeC5H3CH3CH2N((CH2)2CH3)3(1+)*I(1-)=C5H5FeC5H3CH3CH2N((CH2)2CH3)3I
793687-34-0, 801317-78-2, 366796-05-6

C5H5FeC5H3CH3CH2N((CH2)2CH3)3(1+)*I(1-)=C5H5FeC5H3CH3CH2N((CH2)2CH3)3I

Conditions
ConditionsYield
In acetonitrile ferrocenyl deriv. refluxed with 3 equiv. of a tertiary amine for 17-18 hunder Ar; cooled., evapd., residue dissolved in acetone, diluted with a large amt.of Et2O and left to stand at -2-4°C; crystalline ppt. collected;93.6%
tri-n-propylamine
102-69-2

tri-n-propylamine

iodobenzene
591-50-4

iodobenzene

carbon monoxide
201230-82-2

carbon monoxide

N,N-dipropylbenzamide
14657-86-4

N,N-dipropylbenzamide

Conditions
ConditionsYield
With palladium 10% on activated carbon; oxygen In acetonitrile at 100℃; under 4560.31 Torr; for 8h; Autoclave; Green chemistry;93%
With palladium dichloride In water at 80℃; under 760.051 Torr; for 8h; Green chemistry;85%
With iodophenylbis(triphenylphosphine)palladium at 120℃; for 67h;23.9%
tri-n-propylamine
102-69-2

tri-n-propylamine

tri-n-propylammonium tetrafluoridoborate

tri-n-propylammonium tetrafluoridoborate

Conditions
ConditionsYield
With tetrafluoroboric acid In water at 0℃; for 0.5h;93%
With tetrafluoroboric acid In water at 40 - 60℃; for 24h;87.2%
With tetrafluoroboric acid In water at -0.16℃;36.5%
tri-n-propylamine
102-69-2

tri-n-propylamine

tetrafluoroboric acid

tetrafluoroboric acid

tri-n-propylammonium tetrafluoridoborate

tri-n-propylammonium tetrafluoridoborate

Conditions
ConditionsYield
In water for 0.5h; Cooling with ice;93%
In water for 0.5h; Cooling with ice;93%
tri-n-propylamine
102-69-2

tri-n-propylamine

2K(1+)*(CF3)3BCO2(2-)=K2(CF3)3BCO2

2K(1+)*(CF3)3BCO2(2-)=K2(CF3)3BCO2

HN(C3H7)3(1+)*(CF3)3BCO2H(1-)=HN(C3H7)3(CF3)3BCO2H

HN(C3H7)3(1+)*(CF3)3BCO2H(1-)=HN(C3H7)3(CF3)3BCO2H

Conditions
ConditionsYield
With hydrogenchloride92%
tri-n-propylamine
102-69-2

tri-n-propylamine

dimethyl acetylenedicarboxylate
762-42-5

dimethyl acetylenedicarboxylate

dimethyl (2E)-2-(dipropylamino)but-2-enedioate

dimethyl (2E)-2-(dipropylamino)but-2-enedioate

Conditions
ConditionsYield
With chlorotribromomethane; Eosin Y In dichloromethane; water at 20℃; for 3h; Irradiation;92%
With antimony(III) chloride In 1,4-dioxane at 80℃; for 5h;74%
With Eosin Y; water; oxygen In toluene at 20℃; for 20h; Schlenk technique; Irradiation;60%
tri-n-propylamine
102-69-2

tri-n-propylamine

5,6-dihydro-6-ethyl-5-oxo-2-piperazinopyrido[4,3-d]pyrimidine
102828-53-5

5,6-dihydro-6-ethyl-5-oxo-2-piperazinopyrido[4,3-d]pyrimidine

2-chloro-6,7-dimethoxy-quinazoline
94644-47-0

2-chloro-6,7-dimethoxy-quinazoline

6,7-Dimethoxy-2-(4-(5,6-dihydro-6-ethyl-5-oxopyrido[4,3-d]pyrimidine-2-yl)piperazino)quinazoline

6,7-Dimethoxy-2-(4-(5,6-dihydro-6-ethyl-5-oxopyrido[4,3-d]pyrimidine-2-yl)piperazino)quinazoline

Conditions
ConditionsYield
In i-Amyl alcohol92%
hydrogenchloride
7647-01-0

hydrogenchloride

tri-n-propylamine
102-69-2

tri-n-propylamine

2K(1+)*(CF3)3BCO2(2-)=K2(CF3)3BCO2

2K(1+)*(CF3)3BCO2(2-)=K2(CF3)3BCO2

HN(C3H7)3(1+)*(CF3)3BCO2H(1-)=HN(C3H7)3(CF3)3BCO2H

HN(C3H7)3(1+)*(CF3)3BCO2H(1-)=HN(C3H7)3(CF3)3BCO2H

Conditions
ConditionsYield
In water concd. HCl and N(C3H7)3 were added to a soln. of salt in water with stirring; the mixt. was extd. with CH2Cl2, dried over MgSO4, filtered, the solventwas removed under reduced pressure;92%
tri-n-propylamine
102-69-2

tri-n-propylamine

4-methoxy-aniline
104-94-9

4-methoxy-aniline

N-(4-methoxyphenyl)-N-propylamine
71193-47-0

N-(4-methoxyphenyl)-N-propylamine

Conditions
ConditionsYield
With [(phenylbenzothiazole)2Ir(nBu)3]OTf In 5,5-dimethyl-1,3-cyclohexadiene at 155℃; for 10h; Inert atmosphere; Schlenk technique;92%
With μ-diiodo-di((η5-pentamethylcyclopentadienyl)(iodo)iridium) In 5,5-dimethyl-1,3-cyclohexadiene at 155℃; for 10h; Inert atmosphere;90%
tri-n-propylamine
102-69-2

tri-n-propylamine

o-toluidine
95-53-4

o-toluidine

2-methyl-N-propylaniline
83627-55-8

2-methyl-N-propylaniline

Conditions
ConditionsYield
With palladium 10% on activated carbon In toluene at 175℃; for 1.5h; Inert atmosphere; Microwave irradiation;92%
benzoxazole
273-53-0

benzoxazole

tri-n-propylamine
102-69-2

tri-n-propylamine

N,N-dipropylbenzo[d]oxazol-2-amine
1262296-99-0

N,N-dipropylbenzo[d]oxazol-2-amine

Conditions
ConditionsYield
With oxygen; acetic acid; copper(ll) bromide In 1,4-dioxane at 120℃; under 760.051 Torr; for 16h;92%
1,4-dibromo-butane
110-52-1

1,4-dibromo-butane

tri-n-propylamine
102-69-2

tri-n-propylamine

N1,N1,N1,N4,N4,N4-hexapropylbutane-1,4-diaminium dibromide

N1,N1,N1,N4,N4,N4-hexapropylbutane-1,4-diaminium dibromide

Conditions
ConditionsYield
In ethanol Reflux; Inert atmosphere;92%
tri-n-propylamine
102-69-2

tri-n-propylamine

tri-n-propylammonium hexafluoridophosphate

tri-n-propylammonium hexafluoridophosphate

Conditions
ConditionsYield
With hexafluorophosphoric acid In water for 0.25h; Cooling with ice;92%

Tripropylamine Consensus Reports

Reported in EPA TSCA Inventory.

Tripropylamine Standards and Recommendations

DOT Classification:  3; Label: Flammable Liquid, Corrosive

Tripropylamine Specification

The Tripropylamine is an organic compound with the formula C9H21N. The IUPAC name of this chemical is N,N-dipropylpropan-1-amine. With the CAS registry number 102-69-2, it is also named as 1-propanamine, N,N-dipropyl-. The product's categories are Amines; C9 to C10; Nitrogen Compounds. Besides, it is colourless liquid, which is used for producting drugs, pesticides, rubber and fiber processing aids, etc.

Physical properties about Tripropylamine are: (1)ACD/LogP: 3.25; (2)ACD/LogD (pH 5.5): 0.17; (3)ACD/LogD (pH 7.4): 0.78; (4)ACD/BCF (pH 5.5): 1; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 1.16; (7)ACD/KOC (pH 7.4): 4.71; (8)#H bond acceptors: 1; (9)#Freely Rotating Bonds: 6; (10)Polar Surface Area: 3.24 Å2; (11)Index of Refraction: 1.428; (12)Molar Refractivity: 47.46 cm3; (13)Molar Volume: 184.3 cm3; (14)Polarizability: 18.81×10-24cm3; (15)Surface Tension: 25.9 dyne/cm; (16)Density: 0.777 g/cm3; (17)Flash Point: 36.7 °C; (18)Enthalpy of Vaporization: 39.48 kJ/mol; (19)Boiling Point: 158.1 °C at 760 mmHg; (20)Vapour Pressure: 2.66 mmHg at 25°C.

Preparation: this chemical can be prepared by 1-nitro-propane. This reaction will need reagent CO, H2O, catalyst Rh6(CO)16-amine polymer and solvent 2-ethoxy-ethanol. The reaction time is 48 hours with reaction temperature of 40 °C. The yield is about 32%.



Uses of Tripropylamine: it can be used to produce ethyl-tripropyl-ammonium; iodide by heating. It will need reagent butan-2-one with reaction time of 2 hours. The yield is about 40%.

When you are using this chemical, please be cautious about it as the following:
It is flammable and harmful by inhalation and in contact with skin. It is toxic by inhalation and if swallowed and can cause burns. Please keep away from sources of ignition - No smoking. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Besides, this chemical is harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. When you are using it, wear suitable gloves and eye/face protection. In case of accident or if you feel unwell seek medical advice immediately (show the label where possible).

You can still convert the following datas into molecular structure:
(1)SMILES: N(CCC)(CCC)CCC
(2)InChI: InChI=1/C9H21N/c1-4-7-10(8-5-2)9-6-3/h4-9H2,1-3H3
(3)InChIKey: YFTHZRPMJXBUME-UHFFFAOYAE
(4)Std. InChI: InChI=1S/C9H21N/c1-4-7-10(8-5-2)9-6-3/h4-9H2,1-3H3
(5)Std. InChIKey: YFTHZRPMJXBUME-UHFFFAOYSA-N

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mammal (species unspecified) LC50 inhalation 5100mg/m3 (5100mg/m3)   Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 14, Pg. 80, 1975.
mammal (species unspecified) LD50 unreported 740mg/kg (740mg/kg)   Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 14, Pg. 80, 1975.
mouse LC50 inhalation 3800mg/m3/2H (3800mg/m3)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 118, 1982.
rabbit LD50 skin 570uL/kg (0.57mL/kg)   American Industrial Hygiene Association Journal. Vol. 30, Pg. 470, 1969.
rat LC50 inhalation 5100mg/m3/4H (5100mg/m3)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 118, 1982.
rat LD50 oral 96mg/kg (96mg/kg)   American Industrial Hygiene Association Journal. Vol. 30, Pg. 470, 1969.

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