cis-1,4-Dichloro-2-butene supplier

Name
cis-1,4-Dichloro-2-butene
EINECS 216-021-5
CAS No. 1476-11-5
Article Data35
CAS DataBase
Density 1.126 g/cm³
Solubility Not miscible or difficult to mix in water. Soluble in alcohol, ether, acetone and benzene.
Melting Point -48 °C
Formula C₄H₆Cl₂
Boiling Point 155.5 °C at 760 mmHg
Molecular Weight 124.998
Flash Point 54.4 °C
Transport Information UN 3390 6.1/PG 1
Appearance light-yellow clear liquid
Safety 53-26-28-36/37/39-45-60-61
Risk Codes 45-24/25-26-34-50/53
Molecular Structure
Hazard Symbols T+,N
Synonyms 2-Butene,1,4-dichloro-, (Z)- (8CI);(2Z)-1,4-Dichloro-2-butene;(Z)-1,4-Dichlorobutene;1,4-Dichloro-cis-2-butene;cis-1,2-Bis(chloromethyl)ethene;2-Butene,1,4-dichloro-, (2Z)-;
PSA 0.00000
LogP 2.02020

Synthetic route

: 6117-80-2
1,4-butenediol

: 1476-11-5
Z-1,4-dichlorobutene

Conditions

Conditions	Yield
With 1,2,3-Benzotriazole; thionyl chloride In dichloromethane at 20℃; Substitution;	94%
With thionyl chloride at 20℃; for 16h; Cooling with ice;	84%
With thionyl chloride at 20℃; for 16.66h; Cooling with ice; Inert atmosphere;	84%

: 1953-56-6, 70886-56-5, 2303-47-1
(Z)-but-2-ene-1,4-diyl dimethanesulfonate

: 1476-11-5
Z-1,4-dichlorobutene

Conditions

Conditions	Yield
With calcium chloride In dimethyl sulfoxide for 3h; Ambient temperature;	60%

: 1708-29-8
2,5-dihydrofuran

: 1476-11-5
Z-1,4-dichlorobutene

Conditions

Conditions	Yield
With thionyl chloride; zinc(II) chloride at 80 - 85℃;
With hydrogenchloride at 90℃; for 4h;	4.2 g

: 106-99-0
buta-1,3-diene

A: 1476-11-5
Z-1,4-dichlorobutene

B: 110-57-6
trans-1,4-dichlorobut-2-ene

C: 310447-99-5, 310448-01-2
3,4-dichlorobut-1-ene

Conditions

Conditions	Yield
With iodine; copper dichloride In benzene at 70℃; for 2h;
With copper dichloride In acetonitrile at 60℃; for 2h;

...Expand

: 110-57-6
trans-1,4-dichlorobut-2-ene

: 1476-11-5
Z-1,4-dichlorobutene

Conditions

Conditions	Yield
at 99.9℃; Kinetics; Thermodynamic data; Equilibrium constant; activation parameters;

: 821-10-3
1,4-Dichloro-2-butyne

: 110-83-8
cyclohexene

: 1476-11-5
Z-1,4-dichlorobutene

Conditions

Conditions	Yield
With borane; acetic acid Product distribution; multistep reaction, stereospecificity, various alkenes;

: 310447-99-5, 310448-01-2
3,4-dichlorobut-1-ene

A: 1476-11-5
Z-1,4-dichlorobutene

B: 110-57-6
trans-1,4-dichlorobut-2-ene

Conditions

Conditions	Yield
With poly(p-xylylene); palladium In toluene at 99.85℃; Product distribution;
With oxygen at 100℃;

: 1708-29-8
2,5-dihydrofuran

: 7719-09-7
thionyl chloride

: 5435-44-9, 22243-66-9
(E)-3-Ureido-but-2-enoic acid ethyl ester

: 1476-11-5
Z-1,4-dichlorobutene

...Expand

: 7647-01-0
hydrogenchloride

: 6117-80-2
1,4-butenediol

A: 1476-11-5
Z-1,4-dichlorobutene

B cis-4-chloro-buten-(2)-ol-(1): cis-4-chloro-buten-(2)-ol-(1)

Conditions

Conditions	Yield
at 40℃;

...Expand

: 1476-11-5
Z-1,4-dichlorobutene

: 100-97-0
hexamethylenetetramine

: 117175-09-4
1-<(Z)-4-Chloro-2-butenyl>-1-azonia-3,5,7-triazatricyclo<3.3.1.1.3,7>decane chloride

Conditions

Conditions	Yield
In dichloromethane for 5h; Reflux; Large scale reaction;	100%
In ethanol; chloroform for 4h; Heating;	99%
In chloroform at 60℃; for 4h;	94%
In chloroform for 4h; Heating;	91%
In chloroform for 4h; Reflux;	91%

: 1476-11-5
Z-1,4-dichlorobutene

: sodium methanetricarboxylic acid triethyl ester

: 262863-53-6
triethyl 5-chloro-cis-pent-3-ene-1,1,1-tricarboxylate

Conditions

Conditions	Yield
In N,N-dimethyl-formamide; toluene at 80℃; Alkylation;	100%

: 1476-11-5
Z-1,4-dichlorobutene

: 16851-71-1
1-(benzenesulfonyl)-2,5-dihydro-1H-pyrrole

Conditions

Conditions	Yield
Stage #1: benzenesulfonamide With sodium hydride In N,N-dimethyl-formamide at 20℃; for 0.166667h; Stage #2: Z-1,4-dichlorobutene In N,N-dimethyl-formamide at 20℃; for 20h;	100%

: 1476-11-5
Z-1,4-dichlorobutene

: 28074-23-9
phenylsulfenyl bromide

: 85335-83-7
(2-Bromo-3-chloro-1-chloromethyl-propylsulfanyl)-benzene

Conditions

Conditions	Yield
In dichloromethane for 9h; Ambient temperature;	99%

: 1476-11-5
Z-1,4-dichlorobutene

: 108-59-8
malonic acid dimethyl ester

: 84646-68-4
Dimethyl 3-cyclopentene-1,1-dicarboxylate

Conditions

Conditions	Yield
Stage #1: malonic acid dimethyl ester With lithium hydride In N,N-dimethyl-formamide at 0℃; for 4h; Stage #2: Z-1,4-dichlorobutene In N,N-dimethyl-formamide at 0 - 20℃;	99%
Stage #1: malonic acid dimethyl ester With lithium hydride In N,N-dimethyl-formamide at 0℃; for 2h; Inert atmosphere; Stage #2: Z-1,4-dichlorobutene In N,N-dimethyl-formamide at 0 - 20℃; Inert atmosphere;	87%
Stage #1: malonic acid dimethyl ester With lithium hydride In N,N-dimethyl-formamide at 0℃; for 2h; Stage #2: Z-1,4-dichlorobutene In N,N-dimethyl-formamide at 0 - 25℃; for 72h;	84%

: 1476-11-5
Z-1,4-dichlorobutene

: 189341-51-3
N1,N4-bis(mesitylenesulfonyl)-N4-ethyl-1,4-diaminobutane

: 304862-53-1
N3,N8-bis(mesitylenesulfonyl)-12-chloro-3,8-diaza-(10Z)-dodecane

Conditions

Conditions	Yield
Stage #1: N1,N4-bis(mesitylenesulfonyl)-N4-ethyl-1,4-diaminobutane With sodium hydride In N,N-dimethyl-formamide at 20℃; for 2h; Stage #2: Z-1,4-dichlorobutene In N,N-dimethyl-formamide at 50℃; for 18h; Further stages.;	99%

: 1476-11-5
Z-1,4-dichlorobutene

: 108-95-2
phenol

: 52752-55-3
(Z)-1,4-di(phenoxy)but-2-ene

Conditions

Conditions	Yield
Stage #1: phenol With potassium hydroxide In ethanol for 0.5h; Schlenk technique; Inert atmosphere; Reflux; Stage #2: Z-1,4-dichlorobutene In ethanol at 0 - 20℃; Schlenk technique; Inert atmosphere; Reflux;	98%
Stage #1: phenol With potassium hydroxide In ethanol for 0.25h; Heating; Stage #2: Z-1,4-dichlorobutene at 20℃; for 15h;	75%
(i) NaOH, MeOH, (ii) /BRN= 1719692/; Multistep reaction;

: 1476-11-5
Z-1,4-dichlorobutene

: 109838-85-9
(2R)-2,5-dihydro-2-isopropyl-3,6-dimethoxypyrazine

: 159344-53-3
(Z)-1,4-bis((2S,5R)-5-isopropyl-3,6-dimethoxy-2,5-dihydropyrazin-2-yl)but-2-ene

Conditions

Conditions	Yield
Stage #1: (2R)-2,5-dihydro-2-isopropyl-3,6-dimethoxypyrazine With n-butyllithium In tetrahydrofuran at -78℃; for 0.5h; Inert atmosphere; Stage #2: Z-1,4-dichlorobutene In tetrahydrofuran at 20℃; for 10h; Inert atmosphere;	97.5%

: 1476-11-5
Z-1,4-dichlorobutene

: 304862-42-8
N1,N4-bis(mesitylenesulfonyl)-N4-ethyl-1,4-diamino-2-butene

: 304862-46-2
N3,N8-bis(mesitylenesulfonyl)-12-chloro-3,8-diaza-(5Z,10Z)-dodecadiene

Conditions

Conditions	Yield
Stage #1: N1,N4-bis(mesitylenesulfonyl)-N4-ethyl-1,4-diamino-2-butene With sodium hydride In N,N-dimethyl-formamide at 20℃; for 2h; Stage #2: Z-1,4-dichlorobutene In N,N-dimethyl-formamide at 50℃; for 18h; Further stages.;	97%

: 1476-11-5
Z-1,4-dichlorobutene

: 220166-48-3
N,N'-(1,2-phenylene)bis(4-methoxybenzenesulfonamide)

: C24H24N2O6S2

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile for 24h; Reflux;	97%

: 1476-11-5
Z-1,4-dichlorobutene

: 3406-02-8
bis(phenylsulfonyl)methane

: 110890-37-4
1,1-bis(phenylsulfonyl)-3-cyclopentene

Conditions

Conditions	Yield
With sodium hydroxide; tetrabutyl ammonium fluoride In toluene for 20h; Ambient temperature;	96%

: 1476-11-5
Z-1,4-dichlorobutene

: 2-hydroxy-1-naphthoic acid sodium salt

: 148859-57-8
(2Z)-4-chloro-2-butenyl 2-hydroxy-1-naphthoate

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 25℃; for 17h;	95%

: 1476-11-5
Z-1,4-dichlorobutene

: 75-50-3
trimethylamine

: cis-1-chloro-4-methylammonio-2-butene chloride

Conditions

Conditions	Yield
In tetrahydrofuran for 24h; Ambient temperature;	95%

: 100-02-7
4-nitro-phenol

: 1476-11-5
Z-1,4-dichlorobutene

: 6892-53-1
(Z)-1,4-bis(4-nitrophenoxy)but-2-ene

Conditions

Conditions	Yield
Stage #1: 4-nitro-phenol With potassium hydroxide; 18-crown-6 ether In acetone for 0.25h; Heating; Stage #2: Z-1,4-dichlorobutene for 24h; Heating;	95%

: bis{1,2-bis(methylphosphino)ethane}palladium(II) dichloride

: 1476-11-5
Z-1,4-dichlorobutene

: (1,6,9,14-tetramethyl-1,6,9,14-tetraphosphacyclohexadeca-3,11-diene)palladium dichloride

Conditions

Conditions	Yield
With potassium carbonate In ethanol (under Ar); addn. of K2CO3 and the dihalogenide to a soln. of the Pd complex in EtOH, stirring at room temp. for 12 h; filtn., washing the ppt. with EtOH, evapn. of the solvent under vac. at 40°C, recrystn. from EtOH at -20°C;	95%

: 1476-11-5
Z-1,4-dichlorobutene

: 81307-24-6, 123355-42-0
(11aS)-8-hydroxy-7-methoxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one

: (11aS)-8-[(Z)-4-chloro-but-2-enyloxy]-7-methoxy-1,2,3,11a-tetrahydro-10H-pyrrolo[2,1-c][1,4]benzodiazepine-5-one

Conditions

Conditions	Yield
Stage #1: (11aS)-8-hydroxy-7-methoxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one With potassium carbonate In butanone for 0.5h; Stage #2: Z-1,4-dichlorobutene In butanone for 4h; Reflux;	95%

: 1476-11-5
Z-1,4-dichlorobutene

: 141333-36-0
4-cyanomethyl-2-cyclopentyloxy-1-methoxybenzene

: 401518-81-8
1-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclopen-3-ene-1-carbonitrile

Conditions

Conditions	Yield
Stage #1: 4-cyanomethyl-2-cyclopentyloxy-1-methoxybenzene With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 1h; Stage #2: Z-1,4-dichlorobutene In tetrahydrofuran at -78℃; for 1.5h;	94%
With lithium hexamethyldisilazane In tetrahydrofuran at -78℃;	73%

: 292638-84-7
styrene

: 1476-11-5
Z-1,4-dichlorobutene

: 2687-12-9
cinnamyl chloride

Conditions

Conditions	Yield
tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride In dichloromethane for 12h; Heating;	93%

: 1476-11-5
Z-1,4-dichlorobutene

: 1699-39-4
2-(3-(benzyloxy)-4-methoxyphenyl)acetonitrile

: 763109-95-1
1-(3-benzyloxy-4-methoxyphenyl)cyclopen-3-ene-1-carbonitrile

Conditions

Conditions	Yield
Stage #1: 2-(3-(benzyloxy)-4-methoxyphenyl)acetonitrile With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 1h; Stage #2: Z-1,4-dichlorobutene In tetrahydrofuran at -78℃; for 1.5h;	93%

: 1476-11-5
Z-1,4-dichlorobutene

: 22082-78-6
trifluoromethyl hypochlorite

: 84011-34-7
1,2,4-Trichloro-3-trifluoromethoxy-butane

Conditions

Conditions	Yield
In trichlorofluoromethane at -111 - 22℃; for 20h;	92%

: 1476-11-5
Z-1,4-dichlorobutene

: 155191-86-9
dimethyl 2-oxocyclopentane-1,3-dicarboxylate

: 9-Oxobicyclo[4.2.1]non-3-ene-1,6-dicarboxylic dimethyl ester

Conditions

Conditions	Yield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In toluene at 70℃; for 24h;	92%

: 2947-60-6
3-methylbenzyl cyanide

: 1476-11-5
Z-1,4-dichlorobutene

: 858422-91-0
1-m-tolyl-cyclopent-3-enecarbonitrile

Conditions

Conditions	Yield
Stage #1: 3-methylbenzyl cyanide With sodium t-butanolate In tetrahydrofuran; 1-methyl-pyrrolidin-2-one at 0℃; for 0.5h; Inert atmosphere; Stage #2: Z-1,4-dichlorobutene In tetrahydrofuran; 1-methyl-pyrrolidin-2-one at 0 - 20℃; for 3h; Inert atmosphere;	92%

: 1476-11-5
Z-1,4-dichlorobutene

: 21459-27-8
lead pentafluorothiophenolate

: C16H6F10S2

Conditions

Conditions	Yield
In toluene at 110℃; for 48h; Substitution;	91%

: 1476-11-5
Z-1,4-dichlorobutene

: 172950-95-7
3-bromo-6-methylindolo<2,3-a>pyrrolo<3,4-c>carbazole-5,7-(6H)dione

: 3-bromo-6-methyl-12,13-(but-2-en-1,4-yl)-12,13-dihydro-5,7-dioxo-6H-indolo[2,3-a]pyrrolo[3,4-c]carbazole

Conditions

Conditions	Yield
With caesium carbonate In N,N-dimethyl-formamide at 60℃; for 18h;	91%

: 1476-11-5
Z-1,4-dichlorobutene

: 19472-74-3
2-(2-bromophenyl)acetonitrile

: 1-(2-bromophenyl)cyclopent-3-ene-1-carbonitrile

Conditions

Conditions	Yield
With 1-methyl-pyrrolidin-2-one; sodium t-butanolate In tetrahydrofuran at -10 - 20℃;	91%

: 1476-11-5
Z-1,4-dichlorobutene

: 101-99-5
N-carboethoxyaniline

: ((Z)-4-Chloro-but-2-enyl)-phenyl-carbamic acid ethyl ester

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 40℃; for 5h;	90%

: 1476-11-5
Z-1,4-dichlorobutene

: 5255-71-0
ethyl N-(o-tolyl)carbamate

: ((Z)-4-Chloro-but-2-enyl)-o-tolyl-carbamic acid ethyl ester

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 40℃; for 5h;	90%

: 1476-11-5
Z-1,4-dichlorobutene

: 6135-33-7
carbamic acid, (3-methyphenyl)-, ethyl ester

: ((Z)-4-Chloro-but-2-enyl)-m-tolyl-carbamic acid ethyl ester

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 40℃; for 5h;	90%

: 1476-11-5
Z-1,4-dichlorobutene

: 128886-43-1
[4-(3-Methyl-benzyloxy)-phenyl]-carbamic acid ethyl ester

: ((Z)-4-Chloro-but-2-enyl)-[4-(3-methyl-benzyloxy)-phenyl]-carbamic acid ethyl ester

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 40℃; for 5h;	90%

cis-1,4-Dichloro-2-butene Chemical Properties

IUPAC Name: (Z)-1,4-Dichlorobut-2-ene
Synonyms : Cis-1,4-Dichloro-2-butene ; (2Z)-1,4-Dichloro-2-butene ; (2Z)-1,4-Dichlorobut-2-ene ; 2-Butene, 1,4-dichloro- ; 2-Butene, 1,4-dichloro-, (2Z)-
Molecular formula: C₄H₆Cl₂
Molecular weight: 125.00
CAS NO: 1476-11-5
EINECS: 216-021-5
Index of Refraction: 1.459
Surface Tension: 28 dyne/cm
Molar Refractivity: 30.33 cm³
Molar Volume: 110.9 cm³
Density: 1.126 g/cm³
Flash Point: 54.4 °C
Enthalpy of Vaporization: 37.61 kJ/mol
Boiling Point: 155.5 °C at 760 mmHg
Vapour Pressure: 3.89 mmHg at 25 °C
Melting point : -48 ºC
Storage temp: 2-8 °C
Apperance of cis-1,4-Dichloro-2-butene (CAS NO.1476-11-5): Light-Yellow Clear Liquid

cis-1,4-Dichloro-2-butene Uses

cis-1,4-Dichloro-2-butene (CAS NO.1476-11-5) is used for pyrophendane synthesis.

cis-1,4-Dichloro-2-butene Safety Profile

Hazard Codes: Very T+ Dangerous N
Risk Statements: 45-24-25-26-34-50/53
R45:May cause cancer.
R24:Toxic in contact with skin.
R25 :Toxic if swallowed.
R26:Very toxic by inhalation.
R34:Causes burns.
R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 53-26-28-36/37/39-45-60-61
S53:Avoid exposure - obtain special instructions before use.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S28:After contact with skin, wash immediately with plenty of soap-suds.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S60:This material and its container must be disposed of as hazardous waste.
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: UN 3390 6.1/PG 1
WGK Germany: 3
RTECS: EM4900000
F: 8-21
HazardClass: 8
PackingGroup of cis-1,4-Dichloro-2-butene (CAS NO.1476-11-5): I

Product Name

cis-1,4-Dichloro-2-butene

Synthetic route

cis-1,4-Dichloro-2-butene Chemical Properties

cis-1,4-Dichloro-2-butene Uses

cis-1,4-Dichloro-2-butene Safety Profile

Related Products

Hot Products