Six new isoflavone-based esters, 7-decanoyloxy-3-(4′-substitutedphenyl)-4H-1-benzopyran-4-ones, derived from 1,3-benzenediol (resorcinol) and different para substituted phenylacetic acids have been synthesized and characterized. The molecular structures of the title compounds were elucidated wi...

There is considerable interest in developing new SERMs as multifunctional agents in women's health. Development of dual selective estrogen receptor modulators/VEGFR-2 inhibitors (SERMs/V-2I) has been an attractive strategy for the discovery of new breast cancer therapeutic agents. Our previ...

The direct three-component condensation of resorcinol, 1-(2,4-dihydroxyphenyl)ethanone or 2,4-dihydroxybenzophenone with benzaldehydes and malononitrile to generate some novel 2-amino-3-cyano-4H-chromene derivatives has been carried out over K2CO3 (25 mol%) with high efficiency in water as a gre...

Current study based on the synthesis of new thiazole derivatives via “one pot” multicomponent reaction, evaluation of their in vitro α-glucosidase inhibitory activities, and in silico studies. All synthetic compounds were fully characterized by 1H NMR, 13C NMR and EIMS. CHN analysis was also ...

In this study, (E)-2-[(4-bromophenylimino)methyl]-6-ethoxyphenol compound was investigated by mainly focusing on stacking interactions assembling the supramolecular network of the compound and on tautomerism in solvent media and in the solid state. In doing so, the molecular structure and spectr...

In this study, (E)-2-[(4-bromophenylimino)methyl]-5-(diethylamino)phenol compound was investigated by mainly focusing on conformational isomerism. For this purpose, molecular structure and spectroscopic properties of the compound were experimentally characterized by X-ray diffraction, FT-IR and ...

In the present work, the compound (E)-4-bromo-2-[(4-bromophenylimino)methyl]-6-ethoxyphenol was synthesized and characterized by spectroscopic (FT-IR and UV–Vis) and single crystal X-ray diffraction techniques. The intermolecular contacts in the compound was examined by Hirshfeld surfaces (HS) ...

A series of water-soluble sulfoethylated chitosans (SEC) with degrees of substitution (DS) up to 130% were obtained using a heterogeneous reaction of chitosan with sodium 2-chloroethanesulfonate in 85% isopropanol in the presence of NaOH. NMR and FTIR spectroscopy confirmed that sulfoethylation ...

The liquid crystal cholesteryl 2-(2-ethoxyethoxy) ethyl carbonate was found to be cholesteric up to 32°C, the cholesteryl 2-(2-methoxyethoxy) ethyl carbonate smectic, and the cholesteryl 2-(2-butoxyethoxy) ethyl carbonate cholesteric below −1°C. Our results do not confirm the inversion of rota...

We previously developed a method that can significantly improve Protein A chromatography's capability of removing antibody aggregates. That particular method requires polyethylene glycol (PEG) and 400 mM or more of calcium chloride/sodium chloride to be added to wash and elution buffers. Co...

A comparative analysis of different bacterial communities isolated from the muscles of salted wild bluespot mullet (Valamugil seheli) was performed by the phenotypic, biochemical and 16S rDNA gene sequences analysis. The bacterial composition of the salted mullet was dominated by consisting main...

The chromatographic and chromogenic behavior of 76 nitrogen and carbon substituted hydroxy-, 2-hydroxyethyl-, 2-chloroethyl derivatives and related compounds toward 19 detecting reagents and three solvent systems is described.

A series of benzofuran-2-yl(phenyl)methanone derivatives were synthesized and evaluated as novel probes for β-amyloid plaques. These derivatives were produced by a Rap–Stoermer condensation reaction. Compounds with a N,N-dimethylamino group displayed high affinity for Aβ1–42 aggregates with ...

SIRT1 is a NAD+-dependent deacetylase. Here we described new SIRT1 inhibitors with the scaffold of benzofuran-3-yl(phenyl)methanone. The inhibitors were predicted to bind in C-pocket of SIRT1, forming hydrophobic interactions with Phe273, Phe312 and Ile347. Introducing hydroxyl to meta position ...

Fe(III) meso-tetra(4-carboxyphenyl) porphyrin chloride (Fe-TCP chloride) molecules co-deposited together with 5-(octadecyloxy) isophthalic acid (5-OIA) molecules on a highly-ordered pyrolytic graphite were studied with the help of a scanning tunneling microscope (STM) under ambient conditions. T...

In this work, N-(4-Methylbenzylidene)-N′-(2-carboxyphenyl) hydrazine, C15H14N2O2, Schiff base molecule has been synthesized and characterized by elemental analyses, UV–Vis and IR spectroscopy and single crystal X-ray determination. The molecule of the title compound adopt an E configuration ab...

Various adsorbents are available for the removal of heavy and toxic metals, silica-based materials have been the most popular. Recently, there has been considerable interest for the modification of organic moieties and mesostructured materials to enable their use as efficient adsorbent for metal...

Magnetic nanoparticles of Fe3O4 (MNP) were synthesized by co-precipitating Fe2+ and Fe3+ ions in an ammonia solution. This MNP was coated with silica using sodium metasilicate to obtain silica-coated MNP (MNPSi). Grafting of aminopropyl groups on MNP or MNPSi was performed with (3-aminopropyl)tr...

Herein, we report a facile synthetic protocol to grow thin films of Cu(II) tetrakis(4-carboxyphenyl)porphyrin (CuTCPP) metal-organic frameworks (MOF) from a tetrakis(4-carboxyphenyl)porphyrin (H2TCPP) solution and the copper hydroxide (Cu(OH)2) nanoneedle array formed on a Cu substrate at room t...

SummaryThe effect of two auxin antagonists, 2,3,5-triiodobenzoic acid (TIBA) and 2-(p-chlorophenoxy)-2-methyl propionic acid (CMPA) on brassinosteroid (BR)-induced ethylene biosynthesis in etiolated mung bean hypocotyl (Vigna radiata L. Rwilcz cv. Berken) segments was studied. The maximum inhibi...