Multicopy plasmids carrying either the umuDC operon of Escherichia coli or its analog mucAB operon, were introduced into Ames Salmonella strains in order to analyze the influence of UmuDC and MucAB proteins on repair and mutability after UV irradiation. It was found that in uvr+ bacteria, plasmi...

The role of MucAB and Escherichia coli UmuDC proteins in mutagenesis by 4-quinolone (4-Q) compared to that in UV mutagenesis has been studied in hisG428 Salmonella typhimurium strains. A low-copy plasmid carrying mucAB genes, but not umuDC, promotes reversion of the hisG428 mutation by the 4-Q c...

Caprenin, a randomized triglyceride primarily comprising caprylic (C8:0), capric (C10:0), and behenic (C22:0) acids, was administered in a semi-purified diet to weanling Sprague-Dawley rats (25/sex/group) at dose levels of 5.23, 10.23 or 15.00% (w/w) for 91 days. Corn oil was added at 8.96, 5.91...

A new conjugated polymer, poly{[1′,4′-bis-(thienyl-vinyl)]-2-methoxy-5-(2′-ethylhexyloxy)-1,4-phenylene-vinylene} (PTVMEH-PPV) was synthesized via Grim polymerization. The polymer is soluble in common organic solvents such as chloroform and tetrahydrofuran, and possesses adequate thermal stab...

Langmuir-Blodgett (LB) layers of poly(2-methoxy,5-(2′-ethylhexyloxy)-p-phenylene vinylene) (MEH-PPV) have been built up on quartz and indium-tin oxide (ITO) substrates. The optical properties of the films were characterized using time-correlated single-photon counting, and absorption and steady...

In this work, a novel all-solid-state polymeric membrane Pb2+-selective electrode was developed by using for the first time poly(2-methoxy-5-(2′-ethylhexyloxy)-p-phenylene vinylene) (MEH-PPV) as solid contact. To demonstrate the ion-to-electron transducing ability of MEH-PPV, chronopotentiometr...

The long-term stability of poly{[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylene]vinylene} (MEH-PPV) in solutions exposed to air at daylight and in the dark at room temperature has been studied using the size exclusion chromatography (SEC), UV/vis, fluorescence and IR spectra of aged samples, and co...

The key problem which needs to be solved during the commercialization process of the organic light emitting diode (OLED) lighting technology is how to improve the efficiency and stability of optoelectronic materials. In order to solute this issue, we explore the regulation of Ag nanoparticles (N...

In this study we describe a new retroviral vector utilizing an internal ribosome entry site (IRES) from encephalomyocarditis virus to co-express two genes. One is the herpes simplex virus type 1 thymidine kinase gene (HSV-TK) which induces sensitivity to ganciclovir, and the second is the bacter...

Cancer treatment still requires new compounds to be discovered. Chalcone and its derivatives exhibit anticancer potential in different cancer cells. A new series of benzofuran substituted chalcone derivatives was synthesized by the base-catalyzed Claisen-Schmidt reaction of the 1-(7-ethoxy-1-ben...

The acetyl derivative bearing benzofuran moiety, its enaminone and different hydrazines are used as synthons for the regioselective synthesis of substituted pyrazoles. Their structures were elucidated by 2D 1H-1H COSY, 1H-1H NOESY and 1H-13C HMBC NMR, spectrometry. Also, a series of novel pyrazo...

C-Glycoamino acids bearing a variety of sugar moieties were prepared by the hetero-Diels–Alder addition of ethyl 2-nitrosoacrylate to exo-glycals. The reaction proceeds smoothly to yield spirocyclic oxazines that can be converted into useful products by several hydrogenolytic techniques.

BackgroundThe preliminary characterization of [131I]iodoazomycin arabinoside ([131I]IAZA) as a potential radiotherapeutic radiopharmaceutical is described.

Scintigraphic evaluation of patients with advanced oncological disease showed uptake of radioactivity in the brain following administration of the hypoxic imaging agent 123I-iodoazomycin arabinoside (123I-IAZA). Three proposed metabolites of IAZA—methyl 5-deoxy-5-iodo-D-arabinofuranoside, methy...

A series of amphiphilic and thermo-responsive block copolymers were synthesized by reductive amination between the aldehyde endgroup of hydrophilic HPMC and the amine group of monoamine, diamine, or triamine JEFFAMINE as hydrophobic block. The resulting diblock, triblock and three-armed copolyme...

Soil acidification is one of the most serious “soil diseases” leading to poisonous metal ions release to environment, especially Al3+. To avoid plant poisoned by these ions, it should be a good option that slowing growth rate down at low pH value. Methyl 1-naphthylacetate (MENA), a derivative ...

The effect of montmorillonite and carvacrol (as an antimicrobial agent) on the wettability, mechanical, gas barrier, thermal and color properties of methyl cellulose-based nanocomposite films was investigated. To make a comparison among the film samples, methyl cellulose (MC) film and methyl cel...

Agricultural residues are attractive raw materials for the production of industrial polymers because they are renewable and biodegradable, involve less toxic materials during manufacturing, add value to agricultural by-products, and decrease the global dependence on petroleum-based feedstock. In...

The selective preparation of methyl levulinate (ML) from cellulose is an important step for utilizing natural renewable resource to produce interesting bulk chemicals. However, harsh reaction conditions, particularly high reaction temperatures (180–200 °C), are generally required to overcome t...

Additive manufacturing (AM) is an innovative complex shaping technique with unlimited freedom and flexibility in fabrication. Though the majority of AM processes were focused in polymers, it is later extended to metals and very recently to ceramics. Conventional prototyping of ceramics, especial...