A voltammetric method for the determination of ethyl acetate in ethanol fuel using a Fe3+/Nafion®-coated glassy carbon electrode (GCE) is proposed. The ethyl acetate present in the ethanol fuel was previously converted to acetohydroxamic acid via pretreatment with hydroxylamine chloride. The ace...

An efficient method for palladium-catalyzed CO cross-coupling of ethyl acetohydroxamate (EAcHO) with 4-bromo-chalcones has been developed to synthesize novel chalcones. The two supporting ligands, namely tBuXPhos (L7), and cataCXium®PIntB (L16) were found to be effective ligands towards the Pd-c...

RESUMENObjetivoEvaluar el desprendimiento de tubos adheridos a los primeros molares sobre una superficie de resina sin esmalte dental circundante, los cuales fueron pegados con la misma resina restauradora Empress Direct y la resina Transbond XT, probando tres métodos de preparación de la supe...

SummaryAlthough the bond strength of self-adhesive bonding agents is inferior to that of other families of adhesives, it is still adequate for orthodontic purposes provided prior enamel etching is performed.

ResumenEl propósito de este estudio es comparar la resistencia al desprendimiento que tienen los brackets del esmalte después de 60 minutos y 24 horas de su fijación con dos sistemas diferentes de adhesión. Se utilizaron 60 premolares divididos en 4 grupos de 15 muestras cada uno, fueron tra...

ABSTRACTObjectiveTo assess the detachment of tubes bonded to the first molars on a resin surface without surrounding dental enamel, which were bonded with the same restorative resin Empress Direct and the Transbond XT resin, testing three preparation methods of the resin surface.

The purpose of this study was to compare the resistance when debonding the braces of the enamel after 60 minutes and 24 hours of its fixation with two different adhesive systems. 60 bicuspids where divided into 4 groups of 15 samples each one and were treated with self-etching adhesive SEP Trans...

With an interest to enhance the aroma of palm kernel oil (PKO), Pentopan mono BG (xylanase) was applied to alter the carbohydrates in palm kernels (PK) so as to modulate the formation of volatiles during kernel roasting. The result showed that a 1.3-fold increment of total soluble sugars was fou...

Extant customer-base models like the beta geometric/negative binomial distribution (BG/NBD) predict future purchasing based on customers' observed purchase history. We extend the BG/NBD by adding an important non-transactional element that also drives future purchases: complaint history. Ou...

Malolactomycins A and B are novel 40-membered polyol macrolide antifungal antibiotics which have hemiacetal, malonate and dimethylguanidyl groups. Malolactomycins A and B are positional isomers of malonate and interconvertible each other by transesterification. The structures of malolactomycins ...

A series of [5-substituted-4-phenyl-1,3-thiazol-2-yl] benzamide and furamide analogues were investigated in radioligand binding studies at adenosine receptor subtypes with an aim to obtain potent and selective adenosine receptor ligands. Benzamide and furamide linked to thiazole was found to be ...

Novel heteroaryl-containing benzamide derivatives were synthesized and screened using an in vitro assay measuring increases in glucose uptake and glucokinase activity stimulated by 10 mM glucose in rat hepatocytes. From a library of synthesized compounds, 3-(4-methanesulfonylphenoxy)-N-[1-(2-met...

A series of novel hedgehog signaling pathway inhibitors have been designed by structural modification based on the former reported scaffold of 4-(2-pyrimidinylamino)benzamide. The SAR for this series was described and many derivatives showed potent inhibitory activity. Among these compounds, com...

Antibiotic resistance among clinically significant bacterial pathogens is becoming a prevalent threat to public health, and new antibacterial agents with novel mechanisms of action hence are in an urgent need. Utilizing computational docking method and structure-based optimization strategy, we r...

We report structure-activity relationships of 1-arylsulfonyl indoline based benzamides. The benzamide (9) exhibits striking tubulin inhibition with an IC50 value of 1.1 μM, better than that of combretastain A-4 (3), and substantial antiproliferative activity against a variety of cancer cells, i...

Small samples (5 μl) of rapeseed oil, rapeseed oil methyl ester (RME) and a superior quality diesel oil according to the Swedish environmentally class 1 (SEC1) were oxidised at 550°C in a reactor. The compounds produced were analysed using a gas chromatographic (GC) method: direct gas injectio...

(3Z,6Z,9Z,12E)-Pentadecatetraenal, a common intermediate in the synthesis of methyl Δl7t EPA and methyl Δl9t DHA, was obtained by copper(I)-catalyzed coupling between the Grignard reagent of 1,1-diethoxy-3-butyne and (Z,E)-l-bromo-5,8-undecadien-2-yne followed by semi-hydrogenation of the resu...

This review summarizes recent short-term clinical studies evaluating the ocular hypotensive efficacy of different dose-regimens of latanoprost. When tested in ocular hypertensive and glaucoma patients concomitantly treated with timolol, 0.006% latanoprost given only in the evening, was found to ...

The structures of the title compounds have been established by X-ray crystallography from diffractometry data. Crystals of the first (2c) C2, H21, ClN4O4S · 2H2O are triclinic, space group P1, with a = 9.292(2), b = 11.521(1), c = 12.077 A, a = 102.83(1), β = 95.59(1), γ = 86.98(1), Z = 2, Dc...

Herein we present a tuned cell attachment on self-healable double network hydrogel bearing dynamic covalent bonds and hydrogen bonds. Agar formed first network, while glycol chitosan and oxidized carboxylmethyl cellulose formed second network in the resultant double network hydrogel. Because of ...