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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

2-Amino-5-nitrobenzotrifluoride

Cas:121-01-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2-Amino-5-Nitrobenzotrifluoride

Cas:121-01-7

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

2-Amino-5-Nitrobenzotrifluoride

Cas:121-01-7

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-Amino-5-nitrobenzotrifluoride

Cas:121-01-7

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Benzenamine,4-nitro-2-(trifluoromethyl)- / LIDE PHARMA- Factory supply / Best price

Cas:121-01-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

2-Amino-5-nitrobenzotrifluoride Basic information Product Name: 2-Amino-5-nitrobenzotrifluoride Synonyms: 2-AMINO-5-NITRO-TRIFLUOROBENZENE;2-AMINO-5-NITROBENZOTRIFLUORIDE;2-TRIFLUOROMETHYL-4-NITROANILINE;2-AMino-5-nitrotrifluoroMethylbenzene, 4-n

121-01-7 2-Amino-5-nitrobenzotrifluoride

Cas:121-01-7

Min.Order:10 Metric Ton

FOB Price: $1200.0 / 1300.0

Type:Lab/Research institutions

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Henan Sinotech Import&Export Corporation

Name: 2-Amino-5-nitrobenzotrifluoride Cas No.: 121-01-7 Molecular Formula: C7H5F3N2O2 Molecular weight: 358.1868 Appearance: Snow white powder Storage:Store in cool and dry place, away from sun light. Package:25KG Application: Pharmaceutical In

2-Amino-5-nitrobenzotrifluoride

Cas:121-01-7

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 121-01-7 with fast shipping

Cas:121-01-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Factory Supply High Quality CAS 121-01-7 ,2-AMino-5-nitrobenzotrifluoride

Cas:121-01-7

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

2-Amino-5-nitrobenzotrifluoride

Cas:121-01-7

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzenamine,4-nitro-2-(trifluoromethyl)- 121-01-7

Cas:121-01-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Shanghai Minstar Chemical Co., Ltd

2-Amino-5-nitrobenzotrifluoride Chemical Properties mp 90-92 °C(lit.) BRN 2121347 CAS DataBase Reference 121-01-7(CAS DataBase Reference) NIST Chemistry Reference 2-Amino-5-nitrobenzotrifluoride(121-01-7) Safety Information H

2-Amino-5-nitrobenzotrifluoride 121-01-7 best seller in the market

Cas:121-01-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Benzenamine,4-nitro-2-(trifluoromethyl)-

Cas:121-01-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2-Amino-5-Nitrobenzotrifloride

Cas:121-01-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2-Amino-5-nitrobenzotrifluoride

Cas:121-01-7

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2-Amino-5-nitrobenzotrifluoride

Cas:121-01-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products 2-Amino-5-nitrobenzotrifluoride

Cas:121-01-7

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

2-amino-5-nitrobenzotrifluoride/Manufacturer/High quality/Best price

Cas:121-01-7

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providing h

Factory Supply 2-amino-5-nitrobenzotrifluoride

Cas:121-01-7

Min.Order:0

Negotiable

Type:Other

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

2-AMino-5-nitrobenzotrifluoride

Cas:121-01-7

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermediat

4-Nitro-2-(trifluoromethyl)aniline

Cas:121-01-7

Min.Order:1 Kilogram

FOB Price: $5.0 / 15.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

2-Amino-5-nitrobenzotrifluoride

Cas:121-01-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

2-AMino-5-nitrobenzotrifluoride

Cas:121-01-7

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

2-Amino-5-nitrobenzotrifluoride

Cas:121-01-7

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

2-AMino-5-nitrobenzotrifluoride

Cas:121-01-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

2-AMino-5-nitrobenzotrifluoride

Cas:121-01-7

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

2-Amino-5-nitrobenzotrifluoride

Cas:121-01-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

SAGECHEM/2-Amino-5-nitrotrifluorobenzene

Cas:121-01-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

2-amino-5-nitrobenzotrifluoride

Cas:121-01-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Beijing Greenchem Technology Co.,Ltd. ( Panjin Greenchem Technology Co.Ltd .)

Capability on chemical synthesis1. Beijing High-Tech Enterprises2. Strong R&D Team3. 8 years of experiences in R & D of high-tech Catalyst;4. 5000 production techniques, 69 items of national patents, and 360 kinds of products on sales;5. The producti

2-Amino-5-nitrotrifluorobenzene

Cas:121-01-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Synthetic route

3-trifluoromethylnitrobenzene
98-46-4

3-trifluoromethylnitrobenzene

4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

Conditions
ConditionsYield
With potassium hydroxide; N,N-tetramethylene-thiocarbamoyl-sulphenamide In ammonia91%
With sodium ethanolate; N,N-tetramethylene-thiocarbamoyl-sulphenamide In ammonia; N,N-dimethyl-formamide for 0.583333h;84%
C7H3F3N4O2
1440512-30-0

C7H3F3N4O2

4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

Conditions
ConditionsYield
Stage #1: C7H3F3N4O2 With 3-benzyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride; tert-butyl alcohol In tetrahydrofuran at 20℃; for 0.0833333h; Inert atmosphere;
Stage #2: With sodium t-butanolate In tetrahydrofuran at 20℃; for 12h; Inert atmosphere; chemoselective reaction;
84%
4-chloro-3-(trifluoromethyl)nitrobenzene
777-37-7

4-chloro-3-(trifluoromethyl)nitrobenzene

4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

Conditions
ConditionsYield
With sodium azide; copper(ll) sulfate pentahydrate; sodium carbonate; sodium L-ascorbate; L-proline In water; dimethyl sulfoxide at 70℃; for 24h;72%
With ammonia at 140℃;
With ammonia; copper(l) chloride at 120℃;
With ammonia
Langlois reagent
2926-29-6

Langlois reagent

4-nitro-aniline
100-01-6

4-nitro-aniline

4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

Conditions
ConditionsYield
With tert.-butylhydroperoxide In dichloromethane; water at 0 - 15℃;42%
2-(trifluoromethyl)benzenamine
88-17-5

2-(trifluoromethyl)benzenamine

A

4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

B

2-Nitro-6-(trifluoromethyl)aniline
24821-17-8

2-Nitro-6-(trifluoromethyl)aniline

Conditions
ConditionsYield
With 4-nitro-4-methyl-2,3,5,6-tetrabromo-2,5-cyclohexadien-1-one In trifluoroacetic acid for 3h; Ambient temperature;A 40%
B 30%
3-trifluoromethylnitrobenzene
98-46-4

3-trifluoromethylnitrobenzene

A

4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

B

4-trifluoromethyl-2-nitroaniline
400-98-6

4-trifluoromethyl-2-nitroaniline

Conditions
ConditionsYield
With potassium tert-butylate; N,N-tetramethylene-thiocarbamoyl-sulphenamide In N,N-dimethyl-formamide at 20℃; for 0.333333h;A 29%
B 6%
N-(4-nitro-2-(trifluoromethyl)phenyl)acetamide
395-68-6

N-(4-nitro-2-(trifluoromethyl)phenyl)acetamide

4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

Conditions
ConditionsYield
With sodium hydroxide
3-trifluoromethylnitrobenzene
98-46-4

3-trifluoromethylnitrobenzene

A

4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

B

2-Nitro-6-(trifluoromethyl)aniline
24821-17-8

2-Nitro-6-(trifluoromethyl)aniline

C

4-trifluoromethyl-2-nitroaniline
400-98-6

4-trifluoromethyl-2-nitroaniline

Conditions
ConditionsYield
With O-Methylhydroxylamin; potassium tert-butylate; copper(l) chloride In N,N-dimethyl-formamide for 1h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
With O-Methylhydroxylamin; copper(l) chloride In N,N-dimethyl-formamide at 20℃; for 1h; Product distribution; Further Variations:; also without CuCl; Substitution; Amination;
N-[2-(trifluoromethyl)phenyl]acetamide
344-62-7

N-[2-(trifluoromethyl)phenyl]acetamide

4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: H2SO4; HNO3
2: aq.-ethanolic NaOH
View Scheme
1-chloro-2-(trifluoromethyl)benzene
88-16-4

1-chloro-2-(trifluoromethyl)benzene

4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: HNO3, H2SO4
2: liq. NH3
View Scheme
petroleum

petroleum

S-diethylthiocarbamoyl-substituted sulfenamide
106860-28-0

S-diethylthiocarbamoyl-substituted sulfenamide

3-trifluoromethylnitrobenzene
98-46-4

3-trifluoromethylnitrobenzene

A

4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

B

4-nitro-3-(trifluoromethyl)benzeneamine
393-11-3

4-nitro-3-(trifluoromethyl)benzeneamine

Conditions
ConditionsYield
With sodium hydroxide In N-methyl-acetamide; methanol; ammonia; waterA 3.5 g (85%)
B n/a
pyridine-2-carboxylic acid (4-nitro-phenyl)amide
61349-99-3

pyridine-2-carboxylic acid (4-nitro-phenyl)amide

4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: copper(I) bromide; dipotassium peroxodisulfate / acetonitrile / 12 h / 50 °C
2: hydrogenchloride / ethanol / 12 h / 100 °C
View Scheme
N-(4-nitro-2-(trifluoromethyl)phenyl)picolinamide

N-(4-nitro-2-(trifluoromethyl)phenyl)picolinamide

4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

Conditions
ConditionsYield
With hydrogenchloride In ethanol at 100℃; for 12h;
iodotrifluoromethane
2314-97-8

iodotrifluoromethane

4-nitro-aniline
100-01-6

4-nitro-aniline

4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

Conditions
ConditionsYield
With fac-tris(2-phenylpyridinato-N,C2')iridium(III); potassium carbonate In 1,2-dichloro-ethane at 20℃; for 24h; Inert atmosphere;50.2 g
4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

2-bromo-4-nitro-6-trifluoromethylaniline
400-66-8

2-bromo-4-nitro-6-trifluoromethylaniline

Conditions
ConditionsYield
Stage #1: 4-nitro-2-trifluoromethyl-aniline With hydrogen bromide at 20 - 70℃; for 0.166667h;
Stage #2: With dihydrogen peroxide In water at 60 - 70℃; for 3h;
99.2%
With bromine In acetic acid at 120℃; for 2.5h;91%
With bromine; acetic acid at 120℃; for 2.5h;91%
With bromine In acetic acid 1.) 45 deg C, 2.5 h, 2.) reflux, 4.75 h;81%
With bromine; acetic acid
thiophosgene
463-71-8

thiophosgene

4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

1-isothiocyanato-4-nitro-2-(trifluoromethyl)benzene

1-isothiocyanato-4-nitro-2-(trifluoromethyl)benzene

Conditions
ConditionsYield
With sodium hydrogencarbonate In water; toluene at 0 - 75℃; for 120h; Inert atmosphere;99%
In toluene at 75℃; for 120h; Inert atmosphere;99%
In dichloromethane; water at 0 - 20℃; for 24h; Inert atmosphere;
1,5-pentanedioic acid
110-94-1

1,5-pentanedioic acid

4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

1-(4-nitro-2-trifluoromethyl-phenyl)-piperidine-2,6-dione

1-(4-nitro-2-trifluoromethyl-phenyl)-piperidine-2,6-dione

Conditions
ConditionsYield
With PPA at 80℃; for 12h;98%
4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

2-chloro-4-nitro-6-trifluoromethyl-aniline
400-67-9

2-chloro-4-nitro-6-trifluoromethyl-aniline

Conditions
ConditionsYield
With N-chloro-succinimide In acetonitrile at 150℃; for 0.25h; Microwave irradiation;97%
With N-chloro-succinimide In acetonitrile at 150℃; for 0.166667h; Microwave;75%
With chlorine; acetic acid
succinic acid
110-15-6

succinic acid

4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

1-(4-nitro-2-trifluoromethylphenyl)pyrrolidine-2,5-dione

1-(4-nitro-2-trifluoromethylphenyl)pyrrolidine-2,5-dione

Conditions
ConditionsYield
With PPA at 80℃; for 12h;97%
With PPA at 85℃; for 20h;97%
With polyphosphoric acid at 80℃; for 12h;92%
4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

1-iodo-4-nitro-2-(trifluoromethyl)benzene
400-75-9

1-iodo-4-nitro-2-(trifluoromethyl)benzene

Conditions
ConditionsYield
With sodium iodide; sodium nitrite In sulfuric acid; water94%
With sulfuric acid; acetic acid; potassium iodide; sodium nitrite
With CuI; sodium nitrite In methanol; ice-water; H2SO4/H2O; water
Stage #1: 4-nitro-2-trifluoromethyl-aniline With hydrogenchloride; sodium nitrite In water at 0℃; for 0.5h;
Stage #2: With sodium iodide In water at 0 - 20℃;
4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

Methacryloyl chloride
920-46-7

Methacryloyl chloride

N-(4-nitro-2-(trifluoromethyl)phenyl)methacrylamide

N-(4-nitro-2-(trifluoromethyl)phenyl)methacrylamide

Conditions
ConditionsYield
In N,N-dimethyl acetamide at 20℃;94%
In N,N-dimethyl acetamide at 20℃;94%
In N,N-dimethyl acetamide at 20℃; for 3h; Inert atmosphere;77%
formaldehyd
50-00-0

formaldehyd

4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

1,3,5-tris(4-nitro-2-(trifluoromethyl)phenyl)-1,3,5-triazinane
1628797-85-2

1,3,5-tris(4-nitro-2-(trifluoromethyl)phenyl)-1,3,5-triazinane

Conditions
ConditionsYield
In water at 20℃; for 0.416667h; Ionic liquid; Green chemistry;91%
4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

6-(4-fluorophenyl)-2-pyridinecarboxaldehyde
834884-77-4

6-(4-fluorophenyl)-2-pyridinecarboxaldehyde

2-[(4-nitro-2-trifluoromethylphenylimino)methyl]-6-[4-fluorophenyl]pyridine

2-[(4-nitro-2-trifluoromethylphenylimino)methyl]-6-[4-fluorophenyl]pyridine

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene at 60℃; for 65h; Molecular sieve;91%
4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

methyl 4-formylbenzoate
1571-08-0

methyl 4-formylbenzoate

methyl 4-{[4-nitro-2-(trifluoromethyl)phenylimino]methyl}benzoate
384837-22-3

methyl 4-{[4-nitro-2-(trifluoromethyl)phenylimino]methyl}benzoate

Conditions
ConditionsYield
In ethanol Reflux;90%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

tert-butyl N-tert-butoxycarbonyl-N-[4-nitro-2-(trifluoromethyl)phenyl]carbamate
1089725-58-5

tert-butyl N-tert-butoxycarbonyl-N-[4-nitro-2-(trifluoromethyl)phenyl]carbamate

Conditions
ConditionsYield
With dmap; triethylamine In tetrahydrofuran for 5h; Heating / reflux;88%
With dmap In tetrahydrofuran at 20℃;
With dmap In 1,4-dioxane at 20 - 110℃; for 2h;5.3 g
4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

allyl bromide
106-95-6

allyl bromide

4-nitro-1-(prop-2-en-1-yl)-2-(trifluoromethyl)benzene

4-nitro-1-(prop-2-en-1-yl)-2-(trifluoromethyl)benzene

Conditions
ConditionsYield
With tert.-butylnitrite In acetonitrile at 18 - 26℃; for 1.33h;85%
4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

cyclohexanecarbaldehyde
2043-61-0

cyclohexanecarbaldehyde

N-(4-nitro-2-(trifluoromethyl)phenyl)cyclohexanecarboxamide
1426575-31-6

N-(4-nitro-2-(trifluoromethyl)phenyl)cyclohexanecarboxamide

Conditions
ConditionsYield
Stage #1: 4-nitro-2-trifluoromethyl-aniline With tert.-butylnitrite; trimethylsilylazide In tetrahydrofuran at 0℃;
Stage #2: cyclohexanecarbaldehyde With 3-benzyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride; sodium t-butanolate In tetrahydrofuran at -25℃;
83%
4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

benzaldehyde
100-52-7

benzaldehyde

N-(4-nitro-2-(trifluoromethyl)phenyl)benzamide
121408-37-5

N-(4-nitro-2-(trifluoromethyl)phenyl)benzamide

Conditions
ConditionsYield
Stage #1: 4-nitro-2-trifluoromethyl-aniline With tert.-butylnitrite; trimethylsilylazide In tetrahydrofuran at 0℃;
Stage #2: benzaldehyde With 3-benzyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride; sodium t-butanolate In tetrahydrofuran at -25℃;
77%
4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

3-(N,N-dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one
55314-16-4, 75415-01-9, 123367-26-0

3-(N,N-dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one

N-[4-(pyridin-3-yl)pyrimidin-2-yl]cyanamide
1144477-16-6

N-[4-(pyridin-3-yl)pyrimidin-2-yl]cyanamide

Conditions
ConditionsYield
Stage #1: 4-nitro-2-trifluoromethyl-aniline With nitric acid In ethanol at 0℃;
Stage #2: With CYANAMID In ethanol; water Reflux;
Stage #3: 3-(N,N-dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one In isopropyl alcohol Reflux;
75%
4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

toluene-4-sulfonic acid
104-15-4

toluene-4-sulfonic acid

4-nitro-2-(trifluoromethyl)benzenediazonium tosylate

4-nitro-2-(trifluoromethyl)benzenediazonium tosylate

Conditions
ConditionsYield
With tert.-butylnitrite In ethyl acetate at 20℃; for 0.25h;74%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

N4-(tert-butoxycarbonyl)-2-trifluoromethyl-1,4-phenylenediamine
1016506-18-5

N4-(tert-butoxycarbonyl)-2-trifluoromethyl-1,4-phenylenediamine

Conditions
ConditionsYield
Stage #1: 4-nitro-2-trifluoromethyl-aniline With palladium 10% on activated carbon; hydrogen In methanol under 2068.65 Torr; for 7h;
Stage #2: di-tert-butyl dicarbonate In methanol Reflux;
72.9%
4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

4-nitro-2-(trifluoromethyl)benzenesulfonyl chloride
444-46-2

4-nitro-2-(trifluoromethyl)benzenesulfonyl chloride

Conditions
ConditionsYield
Stage #1: 4-nitro-2-trifluoromethyl-aniline With hydrogenchloride; acetic acid; sodium nitrite In water at 15℃; for 3h; Inert atmosphere;
Stage #2: With sulfur dioxide; copper dichloride In water at 5 - 20℃;
71%
With hydrogenchloride; sulfur dioxide; acetic acid; copper dichloride; sodium nitrite In water at 5 - 20℃;71%
With hydrogenchloride; sulfur dioxide; copper(l) chloride; sodium nitrite 1.) glacial AcOH, from -10 deg C to -5 deg C, 15 min, 2.) glacial AcOH, from 5 deg C to RT, 1.5 h; Yield given. Multistep reaction;
4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

3-tert-Butyl-1-methyl-1H-pyrazole-5-carbonyl chloride
160842-62-6

3-tert-Butyl-1-methyl-1H-pyrazole-5-carbonyl chloride

5-tert-Butyl-2-methyl-2H-pyrazole-3-carboxylic acid (4-nitro-2-trifluoromethyl-phenyl)-amide

5-tert-Butyl-2-methyl-2H-pyrazole-3-carboxylic acid (4-nitro-2-trifluoromethyl-phenyl)-amide

Conditions
ConditionsYield
With pyridine In dichloromethane at 80℃;68%
4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

maleic acid

maleic acid

1-(4-nitro-2-trifluoromethyl-phenyl)-pyrrole-2,5-dione

1-(4-nitro-2-trifluoromethyl-phenyl)-pyrrole-2,5-dione

Conditions
ConditionsYield
With PPA at 80℃; for 12h;68%
4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

1,3-bis(4-nitro-2-(trifluoromethyl)phenyl)triazene
1243357-92-7

1,3-bis(4-nitro-2-(trifluoromethyl)phenyl)triazene

Conditions
ConditionsYield
With hydrogenchloride; sodium nitrite In water at 0 - 20℃; for 48h;68%
4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

3,4-diethoxybenzoic acid
5409-31-4

3,4-diethoxybenzoic acid

3,4-diethoxy-N-(4-nitro-2-(trifluoromethyl)phenyl)benzamide

3,4-diethoxy-N-(4-nitro-2-(trifluoromethyl)phenyl)benzamide

Conditions
ConditionsYield
With phosphorus trichloride In toluene Reflux;64%
5-chloro-2-hydroxybenzoic acid
321-14-2

5-chloro-2-hydroxybenzoic acid

4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

5-chloro-2-hydroxy-N-(4-nitro-2-(trifluoromethyl)phenyl) benzamide

5-chloro-2-hydroxy-N-(4-nitro-2-(trifluoromethyl)phenyl) benzamide

Conditions
ConditionsYield
With phosphorus trichloride In toluene Reflux;63%
4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

Cinnamic acid
621-82-9

Cinnamic acid

(2E)-N-[4-nitro-2-(trifluoromethyl)phenyl]-3-phenylprop-2-enamide

(2E)-N-[4-nitro-2-(trifluoromethyl)phenyl]-3-phenylprop-2-enamide

Conditions
ConditionsYield
With phosphorus trichloride In chlorobenzene at 130℃; for 0.5h; Microwave irradiation;61%
methyl 3-bromobenzoate
618-89-3

methyl 3-bromobenzoate

4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

3-(4-nitro-2-(trifluoromethyl)phenylamino)benzoic acid methyl ester
1359968-17-4

3-(4-nitro-2-(trifluoromethyl)phenylamino)benzoic acid methyl ester

Conditions
ConditionsYield
With palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 20 - 120℃; Buchwald-Hartwig reaction; Inert atmosphere;56%
2,3-Dichloro-1,4-naphthoquinone
117-80-6

2,3-Dichloro-1,4-naphthoquinone

4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

A

2-chloro-3-(4-nitro-2-trifluoromethyl-phenylamino)-[1,4]naphthoquinone

2-chloro-3-(4-nitro-2-trifluoromethyl-phenylamino)-[1,4]naphthoquinone

B

2,3-bis-(4-nitro-2-trifluoromethyl-phenylamino)-[1,4]naphthoquinone

2,3-bis-(4-nitro-2-trifluoromethyl-phenylamino)-[1,4]naphthoquinone

Conditions
ConditionsYield
With sodium t-butanolate; 1,1'-bis-(diphenylphosphino)ferrocene; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride In toluene at 80℃; for 12h;A 55%
B n/a
4-nitro-2-trifluoromethyl-aniline
121-01-7

4-nitro-2-trifluoromethyl-aniline

methyl 4-formylbenzoate
1571-08-0

methyl 4-formylbenzoate

methyl 4-{[4-nitro-2-(trifluoromethyl)phenylamino]methyl}benzoate
1427066-93-0

methyl 4-{[4-nitro-2-(trifluoromethyl)phenylamino]methyl}benzoate

Conditions
ConditionsYield
Stage #1: 4-nitro-2-trifluoromethyl-aniline; methyl 4-formylbenzoate In benzene at 60℃;
Stage #2: With sodium tetrahydroborate; acetic acid In benzene at 0 - 50℃;
55%
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