Reduction of 1,2,4,5-tetrakis(trimethylsilyl)benzene at a sodium-metal mirror under aprotic conditions and an argon atmosphere yields red needles of its solvent-separated radical anion salt. The structure, determined in a 150 K cold N2 flow, is discussed in comparison with that of the neutral st...

Isobaric vapor–liquid equilibrium (VLE) data for the quaternary system sec-butyl alcohol + sec-butyl acetate + N, N-dimethyl formamide (DMF) + dimethyl sulfoxide (DMSO) and the constituent binary system DMF + DMSO were determined at 101.3 kPa with a modified Othmer still. The measured experimen...

This article proposes a novel strategy for enhancing the dispersion and stability of supported H3PW12O40 (HPW) via the charge interaction between HPW anions and amino groups originating from ethylenediamine (ED) grafted on the unsaturated metal sites of MIL-101. Due to its larger specific surfac...

Isobaric vapor–liquid equilibrium (VLE) for the binary system N, N-dimethyl formamide (DMF) + N, N-dimethyl acetamide (DMAC) and the quaternary system sec-butyl alcohol (SBA) + sec-butyl acetate (SBAC) + DMF + DMAC were determined at 101.3 kPa using a vapor–liquid equilibrium still. The thermo...

Isobaric vapor–liquid equilibrium (VLE) data were determined for the binary systems sec-butyl alcohol + N,N-dimethyl formamide (DMF), sec-butyl acetate + DMF and the ternary system sec-butyl alcohol + sec-butyl acetate + DMF at 101.3 kPa using a vapor–liquid equilibrium still. The thermodynami...

Isobaric vapor–liquid equilibrium (VLE) data were measured for the binary systems sec-butyl alcohol + N,N-dimethyl acetamide (DMAC), sec-butyl acetate + DMAC and the ternary system sec-butyl alcohol + sec-butyl acetate + DMAC at 101.3 kPa using a vapor–liquid equilibrium still. The thermodynam...

Isobaric vapor–liquid equilibrium (VLE) data were measured for the binary systems sec-butyl alcohol + dimethyl sulfoxide (DMSO), sec-butyl acetate + DMSO and the ternary system sec-butyl alcohol + sec-butyl acetate + DMSO at 101.3 kPa using a vapor–liquid equilibrium still. The thermodynamic c...

Isobaric vapour-liquid equilibrium (VLE) data for the binary system of {N, N-dimethyl acetamide (DMAC) + dimethyl sulfoxide (DMSO)} and the quaternary system of {sec-butyl acetate (SBAC) + sec-butyl alcohol (SBA) + DMAC + DMSO} were measured at 101.3 kPa using a modified Othmer still. The thermo...

Three kinds of imidazolide basic ionic liquids were prepared and employed as efficient catalysts for the synthesis of sec-butanol from the transesterification of sec-butyl acetate and methanol. The effect of anions and cations of basic ionic liquids on the catalytic activity were explored, and t...

Quaternary Cu/B/Ca/Al2O3 catalyst extrudates were prepared and optimized for hydrogenation of sec-butyl acetate (SBA) to 2-butanol and ethanol. The rationally designed catalyst with a B/Cu molar ratio of 3/1 exhibited an extraordinary resistance to Cu sintering during the reaction over 1000 h, d...

17beta-hydroxysteroid dehydrogenase type 7 (17β-HSD7) promotes breast cancer cell growth via dual-catalytic activity by modulating estradiol and DHT. Here, we clarified the expression pattern of 17β-HSD7 in postmenopausal luminal A type breast cancer with The Cancer Genome Atlas (TCGA) cohort....

Among the family of 17beta-hydroxysteroid dehydrogenases, the type 2 (17beta-HSD 2) is the main enzyme responsible for inactivation of estrogens and androgens, catalyzing the oxidation of the C17 hydroxyl group. 17beta-HSD 2 has been studied only in mammals, its occurrence and function in other ...

17beta-hydroxysteroid dehydrogenase type 1 (17β-HSD1) is a steroidal enzyme which, in breast cancer cells, mainly synthesizes 17-beta-estradiol (E2), an estrogenic hormone that stimulates breast cancer cell growth. We previously showed that the enzyme increased breast cancer cell proliferation ...

The reductive 17β-hydroxysteroid dehydrogenases which catalyze the last step in estrogen activation for estrogen dependent breast cancer cells were studied. Their biological function and the effects of their knockdown for cancer cell proliferation were demonstrated. The multidisciplinary study ...

We tested the hypothesis that 17beta-estradiol would reduce the cerebral O2 consumption response to stimulation of N-methyl-d-aspartate (NMDA) receptors. We determined NMDA receptor density in 10 ovariectomized Wistar female rats equally divided into a control group and 17beta-estradiol (500 μg...

AimsLong-term ovariectomy-induced metabolic changes such as insulin resistance and glucose intolerance might be caused directly by estrogen deficiency and may occur partly as secondary effects of obesity arising due to the orexigenic effects of estrogen deficiency. Long-term estrogen treatment p...

Determining the functional aspects of a gene or protein is a difficult and time-consuming process. De novo analysis is surely the hardest and so it is often quite useful to start with a comparison to functionally or structurally related proteins. Although 17beta-hydroxysteroid dehydrogenase type...

Peroxiredoxin 3 (PRX3) plays a role as a regulator of the adipocyte mitochondrial function due to its antioxidant activity. We have previously reported the existence of a sexual dimorphism in the mitochondrial oxidative stress status of many rat tissues such as white (WAT) and brown (BAT) adipos...

Following transmetalation of (4S)-4-(dibenzylamino)pent-2-enyl(tributyl)stannane with tin(IV) bromide, reactions of the resulting allyltin tribromide with aldehydes gave (3Z)-1,5-syn-5-(dibenzylamino)hex-3-en-1-ols with excellent, ca. 98:2, stereocontrol. (4R)-5-Benzylthio-4-methylpent-2-enyl(tr...

The catalytic system Et2AlCl/TiCl4 induces Diels-Alder cycloaddition of bis(trimethylsilyl)acetylene to 1,3-butadiene, isoprene, 2,3-dimethyl-1,3-butadiene and (E)-1,3-pentadiene affording 1,2-bis(trimethylsuyl)cyclohexa-1,4-dienes in high yields. The cyclohexadienes are readily converted to the...