The infrared spectrum of solid films of thiazyl chloride on varioussubstrates cooled with liquid nitrogen has been investigated from 95 to 4000 cm−1, The investigation showed the existence of two forms of the solid thiazyl chloride films: one form with main peaks at 1346, 350 and 256 cm −1, and ...

Phase behavior of room temperature ionic liquid (RTIL)-H2O mixtures (x = 0.0-98.5 mol% H2O) was investigated by in-situ observations of simultaneous X-ray diffraction and differential scanning calorimetry method, and Raman spectroscopy: The RTIL is N, N-diethyl-N-methyl-N-2-methoxyethyl ammonium...

The induction of sister chromatid exchanges (SCEs) by a 48-h treatment with 3,4-epoxybutane-1,2-diol (EBD), a metabolite of 1,3-butadiene, was studied in whole-blood lymphocyte cultures of 22 human donors with known genotypes of two polymorphic glutathione S-transferases (GSTs), GSTT1 and GSTM1....

Phosphorylation of phenols with dibenzyl phosphite, carbon tetrachloride, N,N-diisopropylethylamine, and catalytic DMAP in acetonitrile at −10°C is rapid, mild, clean, high yielding, and selective.

Rhodium-catalysed phenoxycarbonylation of aryl iodides were carried out under carbon-monoxide atmosphere and in the absence of CO, using paraformaldehyde as an alternative surrogate for carbonylation reactions. Both strategies proved to be efficient for the synthesis of the corresponding phenyl ...

Neuropathic pain is a chronic pain condition that occurs and persists in a heterogeneous group of etiologically different diseases characterized by a primary lesion or dysfunction of the peripheral or central nervous system. Current treatment options do not provide adequate relief for many patie...

A new enzymatic protocol based on lipase-catalyzed cascade toward (E)-α,β-unsaturated carboxylic esters is presented. The proposed methodology consists of elementary organic processes starting from acetals and cyanoacetic acid leading to the formation of desired products in a cascade sequence....

The inhibition of eel acetylcholinesterase and bovine erythrocyte acetylcholinesterase by the 4-nitrophenyl esters of methyl-, ethyl-, and isopropyl(phenyl)phosphinic acid (MPP, EPP, and IPP, respectively) was investigated at pH 6.90 in 0.067 M phosphate buffer (25.0°C) using stopped-flow instr...

The inhibition of eel acetylcholinesterase by the 4-nitrophenyl esters of monochloromethyl(phenyl)-, dichloromethyl(phenyl)-, and phenyl(trichloromethyl)phosphinic acid (I, II, and III, respectively) was investigated at pH 6.90 in 0.067 M phosphate buffer (25.0°C) using stopped-flow instrumenta...

Concentrations of [carboxyl-14C]procaine in blood of mice were increased threefold for 27 min by exposure to O-4-nitrophenyl diphenylphosphinate 2 hr prior to [carboxyl-14C]procaine injection ip, while there was no effect of O-4-nitrophenyl methyl(phenyl)phosphinate pretreatment. There was no ef...

A novel enzyme like polymer catalyst with imidazole moiety has been fabricated on multiwalled carbon nanotubes (MWCNT) by molecular imprinting technology. Molecular imprinted polymers (MIP) were formed from the functional monomer methacryloyl-l-histidine, the transition state analogue (TSA) phen...

A general procedure for the syntheses of diarylmercurials is presented. Reactions proceeded in isopropanol in the presence of a base and arylboronic acid. With one exception, all reactions proceeded in good to excellent yields, and this procedure was applicable to a variety of aromatic and heter...

Thermally promoted reactions of a range of alkynes with the orthomanganated acetophenone (η2-2-acetylphenyl)Mn(CO)4 generally give 1H-inden-1-ols in good yield; effects of substituents and solvent on these reactions are reported, along with the crystal structure of 1-methyl-2,3-diphenyl-1H-inde...

We demonstrated a copper(I)-catalyzed coupling reaction of aryl boronic acids with N,O-acetals and N,N-aminals leading to the synthesis of α-aryl glycines and diarylmethylamines. Under an ambient atmosphere, this catalytic system could be applied to the activation of a C(sp3)-O bond of N,O-acet...

Reactions involving phenol derivatives and acyl chlorides have to be controlled for competitive O-acylations and C-acylations (Friedel–Crafts acylations and Fries rearrangements) in acidic condition. The extent for these reactions in trifluoromethanesulfonic acid (TfOH), which is used as cataly...

An asymmetric carbon center with a tetrafluoroethylene fragment can be efficiently constructed via a highly enantioselective conjugate addition reaction of various arylboronic acids with β-(bromotetrafluoroethyl)-α,β-unsaturated ketones. This system can be successfully applied to an enantiome...

Water-promoted sulfonylation of propargyl esters leading to highly regioselective and stereoselective formation of (Z)-β-sulfonyl enoates in excellent yields, by a simple, mild, and environmentally benign reaction procedure without employing any ligand or additive is reported.

A simple protocol has been established for the preparation of a family of crystalline N-aryl γ-hydroxycrotonamides, useful four-carbon synthons. These were further elaborated to analogs of monastrol having variant ester sidechains, that were evaluated for their anticancer activity employing the...

Copolymers with various contents of 4-acetylphenyl acrylate and glycidyl methacrylate were prepared in 2-butanone solution using benzoyl peroxide as initiator at 70°. The copolymer compositions were determined by 1H-NMR analysis. The reactivity ratios were calculated by both Fineman-Ross and Ke...

The crystals of 3-cyanobenzamide have been obtained in the reaction of MgPcH2O with 1,3-dicyanobenzene. 3-Cyanobenzamide crystallises in the P21/c space group of the monoclinic system with four molecules per unit cell. In the crystal, the 3-cyanobenzamide molecule is non-planar, the amide group ...