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Greenutra Resource Inc

Product Name Brazilian Cocoa Extract Latin Name Theobroma cacao L. Active Ingredient Theobromine Part of used

brazilian cocoa extract

Cas:83-67-0

Min.Order:1 Kilogram

FOB Price: $30.0

Type:Trading Company

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Theobromine Manufacturer/High quality/Best price/In stock

Cas:83-67-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Appearance White powder Complies Identification Positive reaction

High purity Theobromine with high quality and best price cas:83-67-0

Cas:83-67-0

Min.Order:1 Kilogram

FOB Price: $75.0 / 90.0

Type:Manufacturers

inquiry

Kono Chem Co.,Ltd

Phosphosdiesterase inhibitor, weak adenosine receptor antagonist, diuretic and smooth muscle relaxant. Theobromine is a methylxanthine alkaloid and derivative of caffeine that has been found in cocoa beans and has diverse biological activities. It i

83-67-0 discount Theobromine factory

Cas:83-67-0

Min.Order:1 Kilogram

FOB Price: $100.0

Type:Other

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Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

Theobromine Manufacturer/High quality/Best price/In stock CAS NO.83-67-0

Cas:83-67-0

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Manufacturers

inquiry

Xi'an Quanao Biotech Co., Ltd.

Professional Factory We has a complete production and operating system, with an annual output capacity of 2000 tons. It can produce variety of content and proportion of extract according to the demand . Excellent Team We are a young and profess

New Product 99% Theobromine Powder CAS 83-67-0

Cas:83-67-0

Min.Order:1 Kilogram

FOB Price: $50.0

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Theobromine

Cas:83-67-0

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% 1H-Purine-2,6-dione,3,7-dihydro-3,7-dimethyl- 83-67-0 ISO Producer

Cas:83-67-0

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality Theobromine

Cas:83-67-0

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

Cocoa Extract 10% Theobromine

Cas:83-67-0

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Theobromine

Cas:83-67-0

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Theobromine CAS 83-67-0 Xanthan sugar

Cas:83-67-0

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 83-67-0 with best quality

Cas:83-67-0

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Name: Cocoa Bean Extract Powder Activ Ingredient: Theobromine Specifications: 10%, 20% HPLC Product Use: Antisptic, diuretic, ecbolic, emmenagogue and parasiticide Shelf Life: Two years Package: 25kg/drum CAS No.: 83-67-0 Appearance:Fin

Theobromine

Cas:83-67-0

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1H-Purine-2,6-dione,3,7-dihydro-3,7-dimethyl- 83-67-0

Cas:83-67-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

HANWAYS CHEMPHARM CO.,LIMITED

Hanways Chempharm Co., Limited, the former is Hubei Hanways Pharchem CO.,Limited, set up in 2009 in Wuhan, China. We specialize in sourcing and supplying APIs, pharmaceutical intermediates, and fine chemicals for worldwide markets. The founder has d

Theobromine

Cas:83-67-0

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Trading Company

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At pres

Theobromine usd for Weight Loss powder / CAS:83-67-0

Cas:83-67-0

Min.Order:1 Kilogram

FOB Price: $34.0 / 49.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Theobromine CAS: 83-67-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates,

Theobromine CAS: 83-67-0

Cas:83-67-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1H-Purine-2,6-dione,3,7-dihydro-3,7-dimethyl-

Cas:83-67-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

1H-Purine-2,6-dione,3,7-dihydro-3,7-dimethyl-/ LIDE PHARMA- Factory supply / Best price

Cas:83-67-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Wonda Pharm Limited

1.high quality: quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed. 2.reasonable price: we provide high quality products with competitive price in

Manufacturer Supply Pure Natural Cocoa Been Extract Powder 99% Theobromine

Cas:83-67-0

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:83-67-0

Cas:83-67-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures

Theobromine

Cas:83-67-0

Min.Order:1 Kilogram

FOB Price: $40.0 / 60.0

Type:Lab/Research institutions

inquiry

ShangHai Soyoung Biotechnology Inc

Shanghai SOYOUNG onsite assessment conducted by Bureau Veritas commissioned at June 2018. Assessed Supplier of Shanghai SOYOUNG is a faithful and professional supplier of health raw materials in pharmacy, food, cosmetic and other fields for many ye

Theobromine 10%,20% Cocoa extract powder

Cas:83-67-0

Min.Order:25 Kilogram

FOB Price: $50.0

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Theobromine

Cas:83-67-0

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

Theobromine

Cas:83-67-0

Min.Order:1 Kilogram

FOB Price: $1.0 / 100000.0

Type:Lab/Research institutions

inquiry

Chengdu Biopurify Phytochemicals Ltd.

Chengdu Biopurify Phytochemicals Ltd. is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine,Traditional Chinese Medic

Theobromine

Cas:83-67-0

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hefei Zhaobo Technology Co., Ltd.

High quality Caffeic acid CAS 331-39-5 Purity: 99% Min Application: Intermediates Appearance: Powder Package: Bag Delivery: 3-5days Our Advantage & Service 1.Top quality: Using high quality material and establishing a strict quality

Theobromine CAS 83-67-0

Cas:83-67-0

Min.Order:1 Kilogram

FOB Price: $10.0 / 50.0

Type:Trading Company

inquiry

NewCan Biotech Limited

NewCan Biotech Limited was established in 2021 and is primarily engaged in the research, development, production, and sales of sugars, nucleosides, nucleotides, phosphorylated monomers, as well as next-generation antiviral and antitumor drug intermed

Theobromine

Cas:83-67-0

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Theobromine

Cas:83-67-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

1-amino-3,7-dimethylxanthine
81281-47-2

1-amino-3,7-dimethylxanthine

theobromine /
83-67-0

theobromine /

Conditions
ConditionsYield
With sodium nitrite In acetic acid96%
3-methylxanthine
1076-22-8

3-methylxanthine

dimethyl sulfate
77-78-1

dimethyl sulfate

theobromine /
83-67-0

theobromine /

Conditions
ConditionsYield
Stage #1: 3-methylxanthine; dimethyl sulfate With sodium hydrogencarbonate In water; acetone at 55 - 60℃; for 4h;
Stage #2: With hydrogenchloride In water at 80℃; pH=5 - 6; Product distribution / selectivity;
87%
3-methylxanthine disodium salt

3-methylxanthine disodium salt

dimethyl sulfate
77-78-1

dimethyl sulfate

theobromine /
83-67-0

theobromine /

Conditions
ConditionsYield
Stage #1: 3-methylxanthine disodium salt; dimethyl sulfate With sodium carbonate In acetone at 55 - 57℃; for 4h;
Stage #2: With hydrogenchloride In water at 30℃; pH=6; Product distribution / selectivity;
84.9%
3,7,9-trimethylxanthinium hydrogensulfate

3,7,9-trimethylxanthinium hydrogensulfate

theobromine /
83-67-0

theobromine /

Conditions
ConditionsYield
at 260℃; for 1h;66%
3-methylxanthine
1076-22-8

3-methylxanthine

methyl iodide
74-88-4

methyl iodide

A

theobromine /
83-67-0

theobromine /

B

1,7,9-trimethylxanthinium iodide
86180-33-8

1,7,9-trimethylxanthinium iodide

Conditions
ConditionsYield
at 110℃; for 1.5h; closed Kjeldahl flask;A 61%
B 28%
5-amino-3-methyl-3H-imidazole-4-carboxylic acid methylamide; hydrochloride
94453-49-3

5-amino-3-methyl-3H-imidazole-4-carboxylic acid methylamide; hydrochloride

urea
57-13-6

urea

theobromine /
83-67-0

theobromine /

Conditions
ConditionsYield
In melt 1) 140 deg C, 30 min 2) 170-175 deg C, 2h;55%
3,7,9-trimethylxanthinium perchlorate

3,7,9-trimethylxanthinium perchlorate

theobromine /
83-67-0

theobromine /

Conditions
ConditionsYield
In pyridine at 115℃; for 3h;53%
3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
58-08-2

3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione

A

theophylline
58-55-9

theophylline

B

theobromine /
83-67-0

theobromine /

Conditions
ConditionsYield
With sodium thiophenolate at 250℃; for 1.5h;A 37%
B 21%
3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
58-08-2

3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione

A

theophylline
58-55-9

theophylline

B

theobromine /
83-67-0

theobromine /

C

paraxanthine
611-59-6

paraxanthine

Conditions
ConditionsYield
With hepatic cytochrome P450 Enzymatic reaction;A 7%
B 12%
C n/a
theophylline
58-55-9

theophylline

theobromine /
83-67-0

theobromine /

Conditions
ConditionsYield
With sodium thiophenolate at 280℃; for 1.5h;10%
3-methyl-4-amino-5-formylamino-2,6-dioxypyrimidine
14785-95-6

3-methyl-4-amino-5-formylamino-2,6-dioxypyrimidine

theobromine /
83-67-0

theobromine /

Conditions
ConditionsYield
With sodium hydroxide anschliessendes Behandeln mit Dimethylsulfat;
ethanol
64-17-5

ethanol

3,7-dimethyl-3,7-dihydro-purine-2,6-dione, theobromine; salicylate
519-41-5

3,7-dimethyl-3,7-dihydro-purine-2,6-dione, theobromine; salicylate

theobromine /
83-67-0

theobromine /

Conditions
ConditionsYield
Ausscheidung;
3-methyl-5-(N-methyl-ureido)-3H-imidazole-4-carboxylic acid methylamide

3-methyl-5-(N-methyl-ureido)-3H-imidazole-4-carboxylic acid methylamide

acetic acid
64-19-7

acetic acid

theobromine /
83-67-0

theobromine /

Conditions
ConditionsYield
Erhitzen ueber den Schmelzpunkt;
3,7-dimethyl-8-trichloromethyl-3,7-dihydro-purine-2,6-dione
117882-90-3

3,7-dimethyl-8-trichloromethyl-3,7-dihydro-purine-2,6-dione

theobromine /
83-67-0

theobromine /

Conditions
ConditionsYield
With hydrogenchloride
1-benzoyl-3,7-dimethyl-3,7-dihydro-purine-2,6-dione
80038-09-1

1-benzoyl-3,7-dimethyl-3,7-dihydro-purine-2,6-dione

furan-2,3,5(4H)-trione pyridine (1:1)

furan-2,3,5(4H)-trione pyridine (1:1)

glycine
56-40-6

glycine

A

Hippuric Acid
495-69-2

Hippuric Acid

B

theobromine /
83-67-0

theobromine /

Conditions
ConditionsYield
at 20℃;
dimethyl sulfate
77-78-1

dimethyl sulfate

xanthin
69-89-6

xanthin

theobromine /
83-67-0

theobromine /

dimethyl sulfate
77-78-1

dimethyl sulfate

xanthin
69-89-6

xanthin

A

theobromine /
83-67-0

theobromine /

B

3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
58-08-2

3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione

Conditions
ConditionsYield
bei der Methylierung unter verschiedenen Bedingungen;
xanthin
69-89-6

xanthin

methyl iodide
74-88-4

methyl iodide

theobromine /
83-67-0

theobromine /

Conditions
ConditionsYield
at 100℃; Das Bleisalz liefert beim Erhitzen im Rohr;
chloroformic acid ethyl ester
541-41-3

chloroformic acid ethyl ester

3-Methyl-5-methylamino-3H-imidazole-4-carboxylic acid amide; compound with perchloric acid
115377-65-6

3-Methyl-5-methylamino-3H-imidazole-4-carboxylic acid amide; compound with perchloric acid

theobromine /
83-67-0

theobromine /

Conditions
ConditionsYield
With sodium hydroxide; triethylamine 1.) MeCN, r. t., 1.5 h, 2.) r. t., 10 min; Yield given. Multistep reaction;
7,9-dimethylxanthinium iodide
86180-29-2

7,9-dimethylxanthinium iodide

A

theobromine /
83-67-0

theobromine /

B

7-methylxanthine
552-62-5

7-methylxanthine

Conditions
ConditionsYield
at 230℃; for 0.75h; Title compound not separated from byproducts;
7,9-dimethylxanthinium hydrogensulfate

7,9-dimethylxanthinium hydrogensulfate

A

theobromine /
83-67-0

theobromine /

B

7-methylxanthine
552-62-5

7-methylxanthine

Conditions
ConditionsYield
at 250℃; for 0.25h; Title compound not separated from byproducts;
7,9-dimethylxanthinium betaine
5752-21-6

7,9-dimethylxanthinium betaine

theobromine /
83-67-0

theobromine /

Conditions
ConditionsYield
With iodine at 250℃; for 1h;
3,7,9-trimethylxanthinium chloride
86180-34-9

3,7,9-trimethylxanthinium chloride

theobromine /
83-67-0

theobromine /

Conditions
ConditionsYield
at 260℃; for 0.75h; Yield given;
3-methyl-4-methylamino-5-methylformylaminouracil
90198-42-8

3-methyl-4-methylamino-5-methylformylaminouracil

A

theobromine /
83-67-0

theobromine /

B

3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
58-08-2

3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione

Conditions
ConditionsYield
fusion;
1,7,9-trimethylxanthinium iodide
86180-33-8

1,7,9-trimethylxanthinium iodide

theobromine /
83-67-0

theobromine /

Conditions
ConditionsYield
at 230℃; for 0.25h; Yield given;
(5-Carbamoyl-1-methyl-1H-imidazol-4-yl)-methyl-carbamic acid ethyl ester

(5-Carbamoyl-1-methyl-1H-imidazol-4-yl)-methyl-carbamic acid ethyl ester

theobromine /
83-67-0

theobromine /

Conditions
ConditionsYield
With sodium hydroxide for 0.166667h; Heating; Yield given;
3,7-dimethyl-6-(5-oxohexyloxy)-3,7-dihydro-2H-purin-2-one
93079-86-8

3,7-dimethyl-6-(5-oxohexyloxy)-3,7-dihydro-2H-purin-2-one

A

theobromine /
83-67-0

theobromine /

B

6-hydroxy-2-hexanone
21856-89-3

6-hydroxy-2-hexanone

Conditions
ConditionsYield
With hydrogenchloride
3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
58-08-2

3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione

A

formaldehyd
50-00-0

formaldehyd

B

theobromine /
83-67-0

theobromine /

Conditions
ConditionsYield
With Tris-HCl buffer; 1,4-dihydronicotinamide adenine dinucleotide; Pseudomonas putida No. 352 at 25℃; Product distribution; various substrates, enzyme activity;
3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
58-08-2

3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione

A

theophylline
58-55-9

theophylline

B

theobromine /
83-67-0

theobromine /

C

1,3,7-trimethyl-7,9-dihydro-3H-purine-2,6,8-trione
5415-44-1

1,3,7-trimethyl-7,9-dihydro-3H-purine-2,6,8-trione

Conditions
ConditionsYield
With dihydrogen peroxide In water Product distribution; Mechanism; Irradiation; other reagent;
theobromine /
83-67-0

theobromine /

11-chloroundec-1-ene
872-17-3

11-chloroundec-1-ene

1-(10-undecenyl)-3,7-dimethylxanthine
156918-64-8

1-(10-undecenyl)-3,7-dimethylxanthine

Conditions
ConditionsYield
With potassium carbonate In water; dimethyl sulfoxide100%
theobromine /
83-67-0

theobromine /

δ-chlorovaleronitrile
6280-87-1

δ-chlorovaleronitrile

5-(3,7-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)pentanenitrile

5-(3,7-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)pentanenitrile

Conditions
ConditionsYield
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 130℃; for 3h;100%
theobromine /
83-67-0

theobromine /

9-bromo-1-nonene
89359-54-6

9-bromo-1-nonene

1-(8-nonenyl)-3,7-dimethylxanthine
156918-55-7

1-(8-nonenyl)-3,7-dimethylxanthine

Conditions
ConditionsYield
In dimethyl sulfoxide99%
In dimethyl sulfoxide99%
In dimethyl sulfoxide99%
In dichloromethane; dimethyl sulfoxide99%
theobromine /
83-67-0

theobromine /

6-Bromo-1-hexene
2695-47-8

6-Bromo-1-hexene

1-(hex-5-enyl)-3,7-dimethylxanthine
58999-18-1

1-(hex-5-enyl)-3,7-dimethylxanthine

Conditions
ConditionsYield
In water; dimethyl sulfoxide98%
In water; dimethyl sulfoxide95.5%
theobromine /
83-67-0

theobromine /

(E)-1-bromohex-1-ene
13154-13-7

(E)-1-bromohex-1-ene

1-(hex-5-enyl)-3,7-dimethylxanthine
58999-18-1

1-(hex-5-enyl)-3,7-dimethylxanthine

Conditions
ConditionsYield
In water; dimethyl sulfoxide98%
In water; dimethyl sulfoxide98%
In water; dimethyl sulfoxide
In water; dimethyl sulfoxide
theobromine /
83-67-0

theobromine /

(E)-1-bromohex-1-ene
13154-13-7

(E)-1-bromohex-1-ene

A

1-(hex-5-enyl)-3,7-dimethylxanthine
58999-18-1

1-(hex-5-enyl)-3,7-dimethylxanthine

B

1-(5,6-oxidohexyl)-3,7-dimethylxanthine
154719-57-0

1-(5,6-oxidohexyl)-3,7-dimethylxanthine

Conditions
ConditionsYield
In water; dimethyl sulfoxideA 98%
B n/a
In water; dimethyl sulfoxideA 98%
B n/a
theobromine /
83-67-0

theobromine /

8-iodotheobromine
86444-90-8

8-iodotheobromine

Conditions
ConditionsYield
With iodine In acetonitrile for 1.5h; Heating;97%
theobromine /
83-67-0

theobromine /

8-Bromo-1-octene
2695-48-9

8-Bromo-1-octene

1-(7-octenyl)-3,7-dimethylxanthine

1-(7-octenyl)-3,7-dimethylxanthine

Conditions
ConditionsYield
In dimethyl sulfoxide97%
In dimethyl sulfoxide97%
theobromine /
83-67-0

theobromine /

1-bromo-octane
111-83-1

1-bromo-octane

3,7-dimethyl-1-octyl-3,7-dihydro-1H-purine-2,6-dione
103976-48-3

3,7-dimethyl-1-octyl-3,7-dihydro-1H-purine-2,6-dione

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 120℃; Inert atmosphere;96%
With potassium carbonate In N,N-dimethyl-formamide at 120℃; Inert atmosphere; Schlenk technique;88%
With potassium hydroxide; Aliquat 336 1.) 80 deg C, 2 h, 2.) 1 h; Yield given. Multistep reaction;
theobromine /
83-67-0

theobromine /

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

1-(3-chloropropyl)-3,7-dimethyl-2,3,6,7-tetrahydro-1H-2,6-purinedione
74409-52-2

1-(3-chloropropyl)-3,7-dimethyl-2,3,6,7-tetrahydro-1H-2,6-purinedione

Conditions
ConditionsYield
With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride for 2h; Heating;96%
theobromine /
83-67-0

theobromine /

benzyl bromide
100-39-0

benzyl bromide

3,7-dimethyl-9-benzylxanthinium bromide
1243688-83-6

3,7-dimethyl-9-benzylxanthinium bromide

Conditions
ConditionsYield
With potassium iodide for 24h; Reflux; Inert atmosphere;96%
theobromine /
83-67-0

theobromine /

2,6-dichloro-7-methylpurine
2273-93-0

2,6-dichloro-7-methylpurine

Conditions
ConditionsYield
With trichlorophosphate; phosphorus trichloride Substitution;95%
With trichlorophosphate at 140℃;
With N,N-diethylaniline; trichlorophosphate at 130℃; for 18h; Inert atmosphere;
With trichlorophosphate at 140℃;
theobromine /
83-67-0

theobromine /

benzyl bromide
100-39-0

benzyl bromide

1-benzyl-3,7-dimethylxanthine
55247-90-0

1-benzyl-3,7-dimethylxanthine

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; Inert atmosphere; Schlenk technique;95%
Stage #1: theobromine / With potassium carbonate In N,N-dimethyl-formamide for 0.5h;
Stage #2: benzyl bromide In N,N-dimethyl-formamide
89%
With caesium carbonate In toluene; acetonitrile for 18h;80%
theobromine /
83-67-0

theobromine /

allyl bromide
106-95-6

allyl bromide

N-allyltheobromine
2530-99-6

N-allyltheobromine

Conditions
ConditionsYield
Stage #1: theobromine /; allyl bromide With sodium t-butanolate In N,N-dimethyl-formamide at 150℃; for 12h;
Stage #2: In N,N-dimethyl-formamide at 100℃; for 12h;
95%
With potassium carbonate In N,N-dimethyl-formamide80%
With hydrogenchloride In dimethyl sulfoxide42%
theobromine /
83-67-0

theobromine /

1-chloro-5-hexyne
10297-06-0

1-chloro-5-hexyne

1-(hex-5-yn-1-yl)-3,7-dimethyl-1H-purine-2,6(3H,7H)-dione

1-(hex-5-yn-1-yl)-3,7-dimethyl-1H-purine-2,6(3H,7H)-dione

Conditions
ConditionsYield
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 100℃; for 2h;95%
theobromine /
83-67-0

theobromine /

12-phosphotungstic acid*29H2O

12-phosphotungstic acid*29H2O

ethanol
64-17-5

ethanol

O40PW12(3-)*3C7H9N4O2(1+)*1.5C2H6O

O40PW12(3-)*3C7H9N4O2(1+)*1.5C2H6O

Conditions
ConditionsYield
Stage #1: theobromine /; 12-phosphotungstic acid*29H2O In water at 70 - 80℃;
Stage #2: ethanol
95%
methyl bromide
74-83-9

methyl bromide

theobromine /
83-67-0

theobromine /

A

3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
58-08-2

3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione

B

3-benzyladenine
7280-81-1

3-benzyladenine

Conditions
ConditionsYield
With solution aqueuse d'hydroxide de sodium; tetrabutylammomium bromide In dichloromethane 1)20 deg C, 12h 2)40 deg C, 3h;A 94%
B n/a
Iodoethanol
624-76-0

Iodoethanol

theobromine /
83-67-0

theobromine /

1-(2-hydroxyethyl)-3,7-dimethyl-3,7-dihydropurine-2,6-dione
1507-14-8

1-(2-hydroxyethyl)-3,7-dimethyl-3,7-dihydropurine-2,6-dione

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide for 4h;94%
Stage #1: theobromine / With potassium carbonate In N,N-dimethyl-formamide Reflux;
Stage #2: Iodoethanol for 18h; Reflux;
68%
theobromine /
83-67-0

theobromine /

1-propylhalide

1-propylhalide

3,7-Dimethyl-1-propylxanthine
63906-63-8

3,7-Dimethyl-1-propylxanthine

Conditions
ConditionsYield
Stage #1: theobromine / With sodium hydride In dimethyl sulfoxide at 60℃; for 0.333333h; Inert atmosphere;
Stage #2: 1-propylhalide In dimethyl sulfoxide at 60℃; Inert atmosphere;
94%
theobromine /
83-67-0

theobromine /

1-chloro-4-pentyne
14267-92-6

1-chloro-4-pentyne

3,7-dimethyl-1-(pent-4-yn-1-yl)-1H-purine-2,6(3H,7H)-dione

3,7-dimethyl-1-(pent-4-yn-1-yl)-1H-purine-2,6(3H,7H)-dione

Conditions
ConditionsYield
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 100℃; for 2h;94%
theobromine /
83-67-0

theobromine /

5,8-dioxa-spiro[3,4]octane-2-ylmethyl methanesulfonate

5,8-dioxa-spiro[3,4]octane-2-ylmethyl methanesulfonate

1-(5,8-dioxa-spiro[3,4]octane-2-ylmethyl)-3,7-dimethyl-1H-purine-2,6(3H,7H)dione

1-(5,8-dioxa-spiro[3,4]octane-2-ylmethyl)-3,7-dimethyl-1H-purine-2,6(3H,7H)dione

Conditions
ConditionsYield
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 130℃; for 3.5h;93%
theobromine /
83-67-0

theobromine /

dimethyl sulfate
77-78-1

dimethyl sulfate

3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
58-08-2

3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione

Conditions
ConditionsYield
potassium fluoride on basic alumina In acetonitrile for 24h; Ambient temperature;92%
With sodium hydroxide
theobromine /
83-67-0

theobromine /

2,6-dithiotheobromine
18904-08-0

2,6-dithiotheobromine

Conditions
ConditionsYield
With Lawessons reagent; aluminum oxide for 0.116667h; microwave irradiation;92%
With kerosine
theobromine /
83-67-0

theobromine /

bromopentene
1119-51-3

bromopentene

1-(Pent-4-enyl)-3,7-dimethyl-xanthine

1-(Pent-4-enyl)-3,7-dimethyl-xanthine

Conditions
ConditionsYield
In water; dimethyl sulfoxide; Petroleum ether92%
theobromine /
83-67-0

theobromine /

(5-oxohexyl) mesylate

(5-oxohexyl) mesylate

pentoxyphylline
6493-05-6

pentoxyphylline

Conditions
ConditionsYield
With potassium carbonate In ethanol; water at 50℃; for 16h;91.1%
theobromine /
83-67-0

theobromine /

1-bromo-6-hexanol
4286-55-9

1-bromo-6-hexanol

1-(6-hydroxy-hexyl)-3,7-dimethyl-3,7-dihydro-purine-2,6-dione
56395-71-2

1-(6-hydroxy-hexyl)-3,7-dimethyl-3,7-dihydro-purine-2,6-dione

Conditions
ConditionsYield
In water; dimethyl sulfoxide91%
In water; dimethyl sulfoxide91%
ethanol-dichloromethane

ethanol-dichloromethane

theobromine /
83-67-0

theobromine /

1-bromo-6-hexanol
4286-55-9

1-bromo-6-hexanol

1-(6-hydroxy-hexyl)-3,7-dimethyl-3,7-dihydro-purine-2,6-dione
56395-71-2

1-(6-hydroxy-hexyl)-3,7-dimethyl-3,7-dihydro-purine-2,6-dione

Conditions
ConditionsYield
In water; dimethyl sulfoxide91%
In water; dimethyl sulfoxide91%
theobromine /
83-67-0

theobromine /

zirconyl chloride octahydrate

zirconyl chloride octahydrate

ZrO(C5H2N4(O)2(CH3)2)2(C5HN4(O)2(CH3)2)Cl(H2O)

ZrO(C5H2N4(O)2(CH3)2)2(C5HN4(O)2(CH3)2)Cl(H2O)

Conditions
ConditionsYield
In ethanol Zr-compound refluxed in ethanol/triethyl orthoformate for 2 h; N-compound added and refluxed for 36 h; cooled to room temp.; filtered; washed with acetone; elem. anal.;91%
theobromine /
83-67-0

theobromine /

Methyl 4-(bromomethyl)benzoate
2417-72-3

Methyl 4-(bromomethyl)benzoate

4-((3,7-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)methyl)benzoic acid methyl ester

4-((3,7-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)methyl)benzoic acid methyl ester

Conditions
ConditionsYield
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 25 - 110℃; for 3h; Inert atmosphere;91%
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