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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages for Pentoxifylline Cas 6493-05-6 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White powder Storage:Store at RT Package:1kg/foil bag;25kg/drum

High quality Pentoxifylline Cas 6493-05-6 with best price and fast delivery

Cas:6493-05-6

Min.Order:1 Kilogram

FOB Price: $440.0 / 450.0

Type:Trading Company

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Pentoxifylline

Cas:6493-05-6

Min.Order:1

Negotiable

Type:Other

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Pentoxifylline Manufacturer/High quality/Best price/In stock

Cas:6493-05-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Pentoxifylline

Cas:6493-05-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 6493-05-6 with best quality

Cas:6493-05-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry pla

99% Pentoxifylline CAS 6493-05-6 powder with low price

Cas:6493-05-6

Min.Order:100 Gram

Negotiable

Type:Other

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HANWAYS CHEMPHARM CO.,LIMITED

Hanways chempharm is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The marketing department is located in Wuhan. We have two GMP facilities in Hubei Pr

Factory Supply High Quality Pentoxifylline Powder CAS 6493-05-6

Cas:6493-05-6

Min.Order:1 Kilogram

FOB Price: $200.0 / 400.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

1H-Purine-2,6-dione,3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)-

Cas:6493-05-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

Pentoxifylline CAS:6493-05-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediat

Pentoxifylline CAS:6493-05-6

Cas:6493-05-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1H-Purine-2,6-dione,3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)-

Cas:6493-05-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

Pentoxifylline

Cas:6493-05-6

Min.Order:1 Kilogram

FOB Price: $280.0 / 300.0

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1H-Purine-2,6-dione,3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)-

Cas:6493-05-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

Pentoxifylline

Cas:6493-05-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1H-Purine-2,6-dione,3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)-

Cas:6493-05-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Pentoxifylline

Cas:6493-05-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:25kg/drum, or as per your request. Application:Used as Pharmaceutical Intermediates Tr

1H-Purine-2,6-dione,3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)-

Cas:6493-05-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

Pentoxifylline

Cas:6493-05-6

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

Pentoxifylline

Cas:6493-05-6

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

Pentoxifylline

Cas:6493-05-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

Pentoxifylline

Cas:6493-05-6

Min.Order:0

Negotiable

Type:Other

inquiry

Sinoway Industrial Co., Ltd.

Why is SINOWAY:1) Specialized in pharmaceutical and healthcare industrial since 19872) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days.4) We have warehouse in USA with quickly shipment . Application:API

99% up by HPLC Pentoxifylline 1677687

Cas:6493-05-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec Pentoxifylline 100mg

Cas:6493-05-6

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

Pentoxifylline

Cas:6493-05-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

Pentoxifylline

Cas:6493-05-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

1H-Purine-2,6-dione,3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)-

Cas:6493-05-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

Pentoxifylline

Cas:6493-05-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as

Pentoxifylline

Cas:6493-05-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou Huarong Pharm Co., Ltd.

High qualityAppearance:White powder Storage:Room temperature Package:Aluminum bag Application:Used in producing API Transportation:By air Port:Beijing

Pentoxifylline

Cas:6493-05-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

1H-Purine-2,6-dione,3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)-

Cas:6493-05-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25kg,50kg,180kg,200kg,250kg,1000kg,customization Application:Pharma;Industry;Agricultural;chemical reaserch Tran

Pentoxifylline

Cas:6493-05-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

theobromine /
83-67-0

theobromine /

(5-oxohexyl) mesylate

(5-oxohexyl) mesylate

pentoxyphylline
6493-05-6

pentoxyphylline

Conditions
ConditionsYield
With potassium carbonate In ethanol; water at 50℃; for 16h;91.1%
theobromine /
83-67-0

theobromine /

6-Bromo-2-hexanone
10226-29-6

6-Bromo-2-hexanone

pentoxyphylline
6493-05-6

pentoxyphylline

Conditions
ConditionsYield
With sodium hydroxide In isopropyl alcohol at 120℃; for 24h; Yield given;
theobromine /
83-67-0

theobromine /

6-chloro-2-hexanone
10226-30-9

6-chloro-2-hexanone

pentoxyphylline
6493-05-6

pentoxyphylline

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 110℃; for 18h;
theobromine /
83-67-0

theobromine /

pentoxyphylline
6493-05-6

pentoxyphylline

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium methylate / methanol / Inert atmosphere; Reflux
2: sodium iodide / acetone / Reflux
3: (2-(dimethylamino)-N-(quinolin-8-yl)acetamido)nickel(II) chloride; manganese / N,N-dimethyl-formamide / 16 h / 20 °C / Sealed tube
View Scheme
1-(4-chlorobutyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione
78449-22-6

1-(4-chlorobutyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione

pentoxyphylline
6493-05-6

pentoxyphylline

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium iodide / acetone / Reflux
2: (2-(dimethylamino)-N-(quinolin-8-yl)acetamido)nickel(II) chloride; manganese / N,N-dimethyl-formamide / 16 h / 20 °C / Sealed tube
View Scheme
C15H17N3NiO2

C15H17N3NiO2

1-(4-iodobutyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione

1-(4-iodobutyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione

pentoxyphylline
6493-05-6

pentoxyphylline

Conditions
ConditionsYield
With manganese; (2-(dimethylamino)-N-(quinolin-8-yl)acetamido)nickel(II) chloride In N,N-dimethyl-formamide at 20℃; for 16h; Sealed tube;16.6 mg
pentoxyphylline
6493-05-6

pentoxyphylline

3,7-dimethyl-1-(4,4,6,6,6-pentadeutero-5-oxohexyl)-1H-purine-2,6(3H,7H)-dione
1185879-03-1

3,7-dimethyl-1-(4,4,6,6,6-pentadeutero-5-oxohexyl)-1H-purine-2,6(3H,7H)-dione

Conditions
ConditionsYield
With water-d2; potassium carbonate In toluene at 55 - 87℃;99.96%
Stage #1: pentoxyphylline With water-d2; potassium carbonate for 24h; Reflux;
Stage #2: With water-d2 for 24h; Reflux;
93%
With water-d2; potassium carbonate for 48h; Reflux;93%
With water-d2; potassium carbonate In toluene at 87℃;90%
With water-d2; potassium carbonate In toluene at 85 - 87℃; for 4h;
pentoxyphylline
6493-05-6

pentoxyphylline

C13H17(2)HN4O3

C13H17(2)HN4O3

Conditions
ConditionsYield
With potassium tert-butylate; deuterium In tetrahydrofuran at 55℃; under 750.075 Torr; for 24h; regioselective reaction;99%
With deuteromethanol; silver carbonate In tetrahydrofuran at 50℃; for 24h;98%
With [(N,N’-bis(1R,2R,3R,5S)-(−)-isopinocampheyl-1,2-ethanediimine-radical)NiI(μ2-H)]2; deuterium In tetrahydrofuran at -196 - 45℃; under 760.051 Torr; for 24h; Sealed tube;93%
pentoxyphylline
6493-05-6

pentoxyphylline

1-(5-hydroxyhexyl)theobromine
6493-06-7, 100324-80-9, 100324-81-0

1-(5-hydroxyhexyl)theobromine

Conditions
ConditionsYield
With methanol; sodium tetrahydroborate In acetonitrile at 0 - 20℃; for 3.33333h;95%
With sodium tetrahydroborate In methanol at 20℃;92%
With sodium tetrahydroborate In methanol for 1h;80%
pentoxyphylline
6493-05-6

pentoxyphylline

A

lisofylline
100324-81-0

lisofylline

B

(+)-(S)-3,7-dimethyl-1-(5-hydroxyhexyl)-3,7-dihydropurine-2,6-dione
100324-80-9

(+)-(S)-3,7-dimethyl-1-(5-hydroxyhexyl)-3,7-dihydropurine-2,6-dione

Conditions
ConditionsYield
With Saccharomyces cerevisiae KKPU In phosphate buffer at 30℃; for 120h; Product distribution; Further Variations:; Solvents; Temperatures; Reagents; time;A 95%
B n/a
With potassium tert-butylate; hydrogen; C106H135ClIrNO2P2 In propan-1-ol at 20℃; under 6080.41 - 9120.61 Torr; Glovebox; Overall yield = 99 percent; Optical yield = 86 percent ee;
Multi-step reaction with 2 steps
1: sodium tetrahydroborate / methanol; dichloromethane / 0.67 h / 0 - 5 °C
2: immobilized Candida antarctica type B lipase Chirazyme L-2, C-3 / chloroform / 1 h / 60 °C / Sealed tube
View Scheme
pentoxyphylline
6493-05-6

pentoxyphylline

8-bromo-3,7-dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione

8-bromo-3,7-dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione

Conditions
ConditionsYield
With N-Bromosuccinimide In dichloromethane; water for 120h;95%
With N-Bromosuccinimide In dichloromethane; water for 120h;95%
pentoxyphylline
6493-05-6

pentoxyphylline

pentoxifylline-d5
1185995-18-9

pentoxifylline-d5

Conditions
ConditionsYield
With tris(pentafluorophenyl)borate; water-d2 In tetrahydrofuran at 100℃; for 12h; Solvent; Inert atmosphere; regioselective reaction;95%
With water-d2; potassium carbonate at 80℃; for 12h; Reagent/catalyst;
pentoxyphylline
6493-05-6

pentoxyphylline

1-(5-aminohexyl)-3,7-dimethylxanthine

1-(5-aminohexyl)-3,7-dimethylxanthine

Conditions
ConditionsYield
With nickel(II) tetrafluoroborate hexahydrate; ammonia; hydrogen; bis(2-diphenylphosphinoethyl)phenylphosphine In 2,2,2-trifluoroethanol at 120℃; for 24h; chemoselective reaction;93%
With ammonia; hydrogen In tetrahydrofuran at 120℃; for 24h;77%
potassium cyanide

potassium cyanide

ammonium carbonate
506-87-6

ammonium carbonate

pentoxyphylline
6493-05-6

pentoxyphylline

C15H20N6O4

C15H20N6O4

Conditions
ConditionsYield
In ethanol; water at 20℃; for 24h; Bucherer-Bergs Reaction; chemoselective reaction;92%
dibutylamine
111-92-2

dibutylamine

pentoxyphylline
6493-05-6

pentoxyphylline

1-(5-(dibutylamino)hexyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione

1-(5-(dibutylamino)hexyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione

Conditions
ConditionsYield
With palladium 10% on activated carbon; hydrogen In ethanol at 130℃; under 3750.38 - 37503.8 Torr; Autoclave;88%
pentoxyphylline
6493-05-6

pentoxyphylline

2-bromo-2,2-difluoro-1-morpholine-1-yl-ethanone
149229-27-6

2-bromo-2,2-difluoro-1-morpholine-1-yl-ethanone

8-(1,1-difluoro-2-morpholino-2-oxoethyl)-3,7-dimethyl-1-(5-oxohexyl)-3,4,5,7-tetrahydro-1H-purine-2,6-dione

8-(1,1-difluoro-2-morpholino-2-oxoethyl)-3,7-dimethyl-1-(5-oxohexyl)-3,4,5,7-tetrahydro-1H-purine-2,6-dione

Conditions
ConditionsYield
With tris[2-phenylpyridinato-C2,N]iridium(III); potassium acetate In dichloromethane at 20℃; for 36h; Inert atmosphere; Schlenk technique; Irradiation;82%
bis(((trifluoromethyl)sulfinyl)oxy)zinc
39971-65-8

bis(((trifluoromethyl)sulfinyl)oxy)zinc

pentoxyphylline
6493-05-6

pentoxyphylline

3,7-dimethyl-1-(5-oxohexyl)-8-(trifluoromethyl)-3,7-dihydro-1H-purine-2,6-dione
1346252-46-7

3,7-dimethyl-1-(5-oxohexyl)-8-(trifluoromethyl)-3,7-dihydro-1H-purine-2,6-dione

Conditions
ConditionsYield
With tert.-butylhydroperoxide In dichloromethane; water at 25℃;79%
With tetraethylammonium perchlorate In dimethyl sulfoxide at 20℃; for 8h; Reagent/catalyst; Electrochemical reaction;53%
pentoxyphylline
6493-05-6

pentoxyphylline

C26H34N8O5

C26H34N8O5

Conditions
ConditionsYield
With sodium ethanolate In isopropyl alcohol at 0 - 60℃; for 2h; Temperature; Reagent/catalyst; Solvent;77.2%
Langlois reagent
2926-29-6

Langlois reagent

pentoxyphylline
6493-05-6

pentoxyphylline

3,7-dimethyl-1-(5-oxohexyl)-8-(trifluoromethyl)-3,7-dihydro-1H-purine-2,6-dione
1346252-46-7

3,7-dimethyl-1-(5-oxohexyl)-8-(trifluoromethyl)-3,7-dihydro-1H-purine-2,6-dione

Conditions
ConditionsYield
With mesoporous graphitic carbon nitride In dimethyl sulfoxide at 25℃; Irradiation;76%
With lithium perchlorate; 9-(2-mesityl)-10-methylacridinium perchlorate In acetonitrile at 23℃; for 16h; Inert atmosphere; Irradiation; Electrochemical reaction;72%
benzonitrile
100-47-0

benzonitrile

pentoxyphylline
6493-05-6

pentoxyphylline

1-(5-(benzylamino)hexyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione hydrochloride

1-(5-(benzylamino)hexyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione hydrochloride

Conditions
ConditionsYield
Stage #1: benzonitrile; pentoxyphylline With hydrogen In 2-methyltetrahydrofuran at 110℃; under 11251.1 Torr; for 20h; High pressure; Autoclave;
Stage #2: With hydrogenchloride In diethyl ether
76%
pentoxyphylline
6493-05-6

pentoxyphylline

methyl iodide
74-88-4

methyl iodide

1-(5-oxohexyl)-3,7,9-trimethylxanthine iodide

1-(5-oxohexyl)-3,7,9-trimethylxanthine iodide

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 75℃; for 48h; Sealed tube;75.2%
pentoxyphylline
6493-05-6

pentoxyphylline

1-(5-hydroxyhexyl-5-d)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione
1185995-43-0

1-(5-hydroxyhexyl-5-d)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione

Conditions
ConditionsYield
With samarium diiodide; water-d2 In tetrahydrofuran at 20℃; for 0.25h; Inert atmosphere; regioselective reaction;75%
With samarium diiodide; water-d2 In tetrahydrofuran at 20℃; for 0.25h; Inert atmosphere; chemoselective reaction;75%
bis(((difluoromethyl)sulfinyl)oxy)zinc

bis(((difluoromethyl)sulfinyl)oxy)zinc

pentoxyphylline
6493-05-6

pentoxyphylline

8-(difluoromethyl)-3,7-dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione
1355729-57-5

8-(difluoromethyl)-3,7-dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione

Conditions
ConditionsYield
With tert.-butylhydroperoxide; trifluoroacetic acid In dichloromethane; water at 23℃; for 22h; regioselective reaction;72%
With tert.-butylhydroperoxide In dichloromethane; water at 25℃;72%
With tert.-butylhydroperoxide; trifluoroacetic acid In dichloromethane; water for 22h;72%
With tert.-butylhydroperoxide In water; dimethyl sulfoxide at 60℃; for 8h; Reagent/catalyst;49%
With tert.-butylhydroperoxide; trifluoroacetic acid In nonane; dimethyl sulfoxide at 20℃;6.8%
pentanonitrile
110-59-8

pentanonitrile

pentoxyphylline
6493-05-6

pentoxyphylline

3,7-dimethyl-1-(5-(pentylamino)hexyl)-3,7-dihydro-1H-purine-2,6-dione hydrochloride

3,7-dimethyl-1-(5-(pentylamino)hexyl)-3,7-dihydro-1H-purine-2,6-dione hydrochloride

Conditions
ConditionsYield
Stage #1: pentanonitrile; pentoxyphylline With hydrogen In 2-methyltetrahydrofuran at 110℃; under 11251.1 Torr; for 20h; High pressure; Autoclave;
Stage #2: With hydrogenchloride In diethyl ether
72%
bis(3-methoxyphenyl)acetylene
59647-77-7

bis(3-methoxyphenyl)acetylene

pentoxyphylline
6493-05-6

pentoxyphylline

A

(E)-1-(5-oxohexyl)-3,7-dimethyl-8-[1,2-di(3-methoxyphenyl)ethenyl]-3,7-dihydro-1H-purine-2,6-dione

(E)-1-(5-oxohexyl)-3,7-dimethyl-8-[1,2-di(3-methoxyphenyl)ethenyl]-3,7-dihydro-1H-purine-2,6-dione

B

(Z)-1-(5-oxohexyl)-3,7-dimethyl-8-[1,2-di(3-methoxyphenyl)ethenyl]-3,7-dihydro-1H-purine-2,6-dione

(Z)-1-(5-oxohexyl)-3,7-dimethyl-8-[1,2-di(3-methoxyphenyl)ethenyl]-3,7-dihydro-1H-purine-2,6-dione

Conditions
ConditionsYield
With 2,2-dimethylbutyric acid; Pd{dba(OMe)}2; tricyclohexylphosphine In 1,4-dioxane at 120℃; for 24h; Inert atmosphere; Overall yield = 78 %;A 70%
B n/a
ammonium hydroxide
1336-21-6

ammonium hydroxide

ammonium chloride

ammonium chloride

pentoxyphylline
6493-05-6

pentoxyphylline

1-(5-aminohexyl)-3,7-dimethylxanthine

1-(5-aminohexyl)-3,7-dimethylxanthine

Conditions
ConditionsYield
With ammonium acetate; sodium cyanoborohydride In methanol; dichloromethane; water68%
ammonium hydroxide
1336-21-6

ammonium hydroxide

ammonium chloride

ammonium chloride

pentoxyphylline
6493-05-6

pentoxyphylline

A

1-(5-aminohexyl)-3,7-dimethylxanthine

1-(5-aminohexyl)-3,7-dimethylxanthine

B

1-(9'-acetoxy-10'-bromodecyl)-3,7-dimethylxanthine

1-(9'-acetoxy-10'-bromodecyl)-3,7-dimethylxanthine

Conditions
ConditionsYield
With ammonium acetate; sodium cyanoborohydride In methanol; dichloromethane; waterA 68%
B n/a
ethanol
64-17-5

ethanol

pentoxyphylline
6493-05-6

pentoxyphylline

8-(1-hydroxyethyl)-3,7-dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione
1016900-98-3

8-(1-hydroxyethyl)-3,7-dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione

Conditions
ConditionsYield
With di-tert-butyl peroxide for 24h; Irradiation;66%
trimethylsilyl trifluoromethanesulfonate
27607-77-8

trimethylsilyl trifluoromethanesulfonate

pentoxyphylline
6493-05-6

pentoxyphylline

3,7-dimethyl-1-(6,6,6-trifluoro-5-methyl-5-(trimethylsilyloxy)hexyl)-1H-purine-2,6(3H,7H)dione

3,7-dimethyl-1-(6,6,6-trifluoro-5-methyl-5-(trimethylsilyloxy)hexyl)-1H-purine-2,6(3H,7H)dione

Conditions
ConditionsYield
With cesium fluoride In tetrahydrofuran at 0 - 20℃; for 2h;66%
2-Aminonicotinaldehyde
7521-41-7

2-Aminonicotinaldehyde

pentoxyphylline
6493-05-6

pentoxyphylline

A

3,7-dimethyl-1-[4-(1,8-naphthyridin-2-yl)butyl]-3,7-dihydro-1H-purine-2,6-dione

3,7-dimethyl-1-[4-(1,8-naphthyridin-2-yl)butyl]-3,7-dihydro-1H-purine-2,6-dione

B

3,7-dimethyl-1-[3-(2-methyl-[1,8]naphthyridin-3-yl)-propyl]-3,7-dihydro-purine-2,6-dione

3,7-dimethyl-1-[3-(2-methyl-[1,8]naphthyridin-3-yl)-propyl]-3,7-dihydro-purine-2,6-dione

Conditions
ConditionsYield
With 1,3,3-trimethyl-6-azabicyclo[3.2.1]octane; sulfuric acid In methanol; ethanol at 60℃; for 2.75h; Friedlaender reaction;A 65%
B n/a
With sodium hydroxide; sulfuric acid In methanol at 65 - 70℃; Friedlaender reaction; Title compound not separated from byproducts;
triphenylmethyl alcohol
76-84-6

triphenylmethyl alcohol

pentoxyphylline
6493-05-6

pentoxyphylline

1-(5-hydroxy-5-phenylhexyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione

1-(5-hydroxy-5-phenylhexyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione

Conditions
ConditionsYield
With potassium phosphate; chloro(1,5-cyclooctadiene)rhodium(I) dimer; potassium tert-butylate; C69H57N2O2(1+)*BF4(1-)*H(1+) In toluene at 125℃; for 24h; Sealed tube;64%
2,2’-bis(benzo[d]isothiazol-3(2H)-one-1,1’-dioxide)-iodobenzene

2,2’-bis(benzo[d]isothiazol-3(2H)-one-1,1’-dioxide)-iodobenzene

pentoxyphylline
6493-05-6

pentoxyphylline

8-(1,1-dioxido-3-oxobenzo[d]isothiazol-2(3H)-yl)-3,7-dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione

8-(1,1-dioxido-3-oxobenzo[d]isothiazol-2(3H)-yl)-3,7-dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione

Conditions
ConditionsYield
With iodine In chloroform at 20℃; for 16h; Irradiation; regioselective reaction;63%
3-azidopropylamine
88192-19-2

3-azidopropylamine

pentoxyphylline
6493-05-6

pentoxyphylline

1-(5-((3-azidopropyl)amino)hexyl)-3,7-dimethyl-1H-purine-2,6(3H,7H)-dione

1-(5-((3-azidopropyl)amino)hexyl)-3,7-dimethyl-1H-purine-2,6(3H,7H)-dione

Conditions
ConditionsYield
Stage #1: 3-azidopropylamine; pentoxyphylline With acetic acid In methanol at 20℃; for 1h;
Stage #2: With sodium tris(acetoxy)borohydride at 20℃; for 2h;
60%
pentoxyphylline
6493-05-6

pentoxyphylline

isopropyl alcohol
67-63-0

isopropyl alcohol

(RS,RS)-1-{[2-hydroxy-2-methylcyclobutyl]methyl}-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione

(RS,RS)-1-{[2-hydroxy-2-methylcyclobutyl]methyl}-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione

B

8-(1-hydroxy-1-methylethyl)-3,7-dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione
1016900-95-0

8-(1-hydroxy-1-methylethyl)-3,7-dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione

C

N-allyltheobromine
2530-99-6

N-allyltheobromine

D

1-(5-hydroxyhexyl)theobromine
6493-06-7, 100324-80-9, 100324-81-0

1-(5-hydroxyhexyl)theobromine

Conditions
ConditionsYield
With acetone for 24h; Irradiation;A 5%
B 55%
C 17%
D 4%
pentoxyphylline
6493-05-6

pentoxyphylline

difluoromethanesulfinate salt

difluoromethanesulfinate salt

8-(difluoromethyl)-3,7-dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione
1355729-57-5

8-(difluoromethyl)-3,7-dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione

Conditions
ConditionsYield
With mesoporous graphitic carbon nitride In dimethyl sulfoxide at 25℃; Irradiation;54%
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