Phytotoxic activity of several middle-chain fatty acids, especially pelargonic acid (C9 acid) was investigated. C9–C11 acids caused strong non-selective damage to plants such as crabgrass, cucumber, velvetleaf, and tobacco, while C6 and C14 fatty acids had almost no activity. Middle-chain fatty...

Substituted α,α-bis(trifluoromethyl)salicylic alcohols react with dichlorido(thio)phosphates in the presence of NEt3 to afford 2-alkoxy-4,4-bis(trifluoromethyl)-4H-1,3,2-benzodioxaphosphinine 2-oxide(sulfides) in high yields. The latter can be of interest as potential cholinesterase inhibitors.

Normal and modified urinary nucleosides represent potential biomarkers for cancer diagnosis. To selectively extract modified nucleosides, we developed a molecularly imprinted polymer (MIP) of 5-methyluridine as selective material for molecularly imprinted solid-phase extraction (MISPE). The MIPs...

Spectroscopic examinatio of purified extracts of the rumen content of sheep intoxicated by Brachiaria decumbens revealed the presence of two spirostanes, identified as epi-sarsasapogenin and epi-smilagenin. Sarsasapogenone was obtained by the oxidation of sarsasapogenin. The reduction of sarsasa...

Using (trifluoromethyl)trimethylsilane (TMSCF3) as the trifluoromethylating agent, MgCl2-catalyzed trifluoromethylation of carbonyl compounds proceeded readily at room temperature. In the presence of 10 mol% of MgCl2, a variety of carbonyl substrates such as aliphatic/aromatic aldehydes, acyclic...

Actin polymerization has been studied in the absence of excess nucleotide. Using G-actin ATP monomers, it was shown that mechanical shearing stimulates ATP hydrolysis. The procedures used enabled the detection of differential effects of phalloidin and tetramethylrhodamine-phalloidin, on the Pi-r...

This study utilized pharmacological activation of Nrf2 with oleanolic acid (OA, 22.5 mg/kg, sc for 4 days) and the genetic alteration of Nrf2 (Nrf2-null, wild-type, and Keap1-HKO mice) to examine the role of Nrf2 in protection against phalloidin hepatotoxicity. Mice were given phalloidin (1.5 mg...

Pulmonary artery hypertension (PAH) is a progressive chronic disease with a high mortality rate. Increased pulmonary vascular resistance and over-proliferation of pulmonary artery endothelial cells lead to remodeling of pulmonary vasculature. Several anti-PAH therapies targeting various pathways...

New (Z)-2-(2-(para-substituted phenyl)hydrazono)-4,4,4-trifluoro-1-(thiophen-2-yl)butane-1,3-diones with chloro (1), bromo (2) and carboxy (3) substituents were synthesized and characterized by ESI-MS, IR, 1H and 13C NMR spectroscopies and elemental analysis. The regioselective carbon–carbon bo...

We re-evaluated 3-bromo-1-trifluoromethanesulfonyloxypropane (3-bromopropyl triflate, 1) as the precursor for the preparation of the fluorine-18 labeled compound 2 by reoptimizing fluorine-18 incorporation reaction conditions (120°C) and developing a method to inactivate the unreacted triflate ...

Fourier-transform (FT)-Raman and FT-infrared spectrum of 4-(3-bromopropyl)-4-azatricyclo [5.2.2.02,6]undecane-3,5,8-trione were recorded and analyzed. The vibrational wavenumbers were examined theoretically using the Gaussian03 set of quantum chemistry codes, and the normal modes were assigned b...

2-Nitro-1-phenyl-1-propanol (NPP) is a nitro alcohol with vasodilator activity in the rat aorta. The present study investigated the vasodilator properties of NPP in small vessels of the mesenteric bed, which, contrary to the aorta, contains resistance vessels. Using myography, isometric contract...

Compounds containing a nitro group may reveal vasodilator properties. Several nitro compounds have a NO2 group in a short aliphatic chain connected to an aromatic group. In this study, we evaluated in rat aorta the effects of two nitro compounds, with emphasis on a putative recruitment of the so...

Nitro compound and nitro derivatives are industrially important to produce rubber and agricultural chemicals. In this study, one of the promising derivatives of nitro compound 2-Nitro-2-phenyl-propane-1,3-diol (2NPP) is examined in detail. FT-Infrared and dispersive Raman spectra of 2NPP (C9H11N...

Dendrites of hydrated cupric chloride crystallized from dihydrated cupric chloride aqueous solutions to which a slight amount of lysed blood from diabetic patients and healthy persons, as controls, was added in vitro, were grown in uncovered petri dishes using a computer-controlled crystal growt...

A new aqueous fire-extinguishing agent (AFEA) – the 40% aqueous solution of CuCl2 – was elaborated. The AFEA was prepared by dissolving copper(II) chloride dihydrate in water. The resulting solution was characterized by a series of physicochemical methods. The ability of the CuCl2-containing A...

Copper etching is considerably important process in electronics industry, particularly in the fabrication of printed circuit board. Various etchants can be used for this purpose, but nowadays cupric chloride is more accepted etchant, because of its high etch rate and easy regeneration properties...

A series of cupric chloride complexes with 1-methyl-5-R-tetrazole ligands, where R = NH2, t-Bu, Ph, MeS, CHCH2, MeSO2, were synthesized by interaction of CuCl2·2H2O with the above ligands LNH2, LtBu, LPh, LMeS, LVin, and LMeSO2, respectively. The obtained complexes [Cu(LNH2)3Cl2]·H2O (1), [Cu(...

Oriental lacquer collected from lacquer trees is widely used as surface coatings for centuries. The lacquer with little activity of laccase is called dead lacquer vividly which cannot be cured automatically. In this study, the cheap copper chloride dihydrate (K2CuCl4·2H2O) was used as a novel c...

The overall structure of the crystallization results of dihydrate cupric chloride with additives in a petri dish is affected by the duration between the beginning of the evaporation and the start of the crystallization. Experiments done with polyvinylpyrrolidone and freeze-dried carrot as additi...