We investigated whether hypertension induced by maternal lipopolysaccharide (LPS) administration during gestation is linked to peripheral vascular and renal hemodynamic regulation, through angiotensin II → NADPH-oxidase signalling, and whether these changes are directly linked to intrauterine o...
The present study aimed to test the hypothesis that high sodium affects the migratory phenotype of endothelial cells (EC) and investigates mechanisms involved independently of hemodynamic factors. Cell migration was evaluated by Wound-Healing at conditions: High Sodium (HS; 160 mM) and Control (...
The safety of 3′-sialyllactose (3′-SL) sodium salt was evaluated by testing for gene mutations, in vivo and in vitro clastogenic activity, and animal toxicity in beagle dogs and rats. The results of all mutagenicity and genotoxicity tests were negative, indicating that 3′-SL does not have any...
The development of axially chiral dicarboxylic acid catalyzed desymmetrizing asymmetric semipinacol rearrangement of symmetrically substituted six-membered cyclic β-hydroxy-α-diazo esters is reported as a means to give chiral cycloheptanones with good enantioselectivities.
A new dicarboxylic acid chloride (2) bearing three preformed imide rings was synthesized by treating N-(3,5-diaminophenyl)phthalimide with trimellitic anhydride followed by refluxing with thionyl chloride. A novel family of aromatic poly(ester-imide)s with inherent viscosities of 0.27–0.35 dl g...
For the selective emission of positive- and negative-sign circularly polarized luminescence (CPL), two chiral organic luminophores with opposing chirality are generally needed. In this study, the solution-state CPL sign of an axially chiral binaphthylacetic acid organic luminophore was successfu...
Three homochiral metal–organic frameworks (MOFs) based on enantiopure chiral ligand: (R)-2,2’-dimethoxy-5,5′,6,6′,7,7′,8,8′-octahydro-1,1′-binaphthyl-3,3′-dicarboxylic acid (H2L), namely Cd(L)(Py)3 1, Cu(L)(Py)3 2, Na[Cd(L)(LH)] · 2.5H2O 3 (Py = pyridine), were firstly synthesized, unde...
Homochiral 2,2′-bis[4-(alkyl)oxazol-2-yl]-1,1′-binaphthyls, which possess both binaphthyl axial chirality and carbon centred chirality, were prepared from 1,1′-binaphthyl-2,2′-dicarboxylic acid and 2-alkyl-2-aminoethanols in high yields. Asymmetric cyclopropanation of styrene with diazoaceta...
A very efficient, chiral phase-transfer catalyst (S)-2Db was prepared by taking advantage of the combinatorial approach from the known, easily available (S)-1,1′-binaphthyl-2,2′-dicarboxylic acid. This catalyst exhibited the high catalytic performance (0.01–0.1 mol %) in the asymmetric alkyla...
Enantiopure 1,1′-binaphthyl-2,2′-dicarboxylic acids (R)-1 and (S)-1 have been synthesized through the lipase-catalyzed kinetic resolution of the racemic 2,2-bis(hydroxymethyl)-1,1′-binaphthyl (±)-2 and subsequent oxidation of the hydroxymethyl groups.
A simple and efficient method has been developed to resolve (±)-2,2′-dihydroxy-1,1′-binaphthyl-3,3′-dicarboxylic acid [(±)-BINOL-3,3′-dicarboxylic acid] (±)-1 using inexpensive and readily accessible chiral resolving agent (1R,2R)-trans-cyclohexane-1,2-diamine 2. Enantiomers of BINOL-3,3′...
We explore the relationship between the (S−1,S) inventory model and three well-known queueing models: the Erlang loss system, the machine-repair model and a two-node Jackson network. Exploiting this relationship allows us to obtain key performance measures of the (S−1,S) model, like the so-calle...
This work evaluates R-454C, R-459B, R-457A and R-455A as R-404A low-GWP substitutes in a stand-alone commercial refrigeration system for fresh product under ISO 23953-2. System is tested with and without receiver. Charge was optimized based on energy consumption tests in climatic chamber. A sign...
The synthesis of 2′,3′-dideoxy-3′-hydroxymethylcytidine 1 was accomplished using two different approaches. First, uridine and cytidine were used to prepare the key intermediate epoxides 15 and 31 which were opened with cyanide, deoxygenated by elimination to vinyl nitriles 17 and 36, and redu...
The antifouling activity of peracetylated cholic acid (1), a bile acid derivative which was isolated in a previous work as a natural product from the Patagonian sponge Siphonochalina fortis, was evaluated in laboratory and field trials. Toxicity and settlement assays were performed with the muss...
Surface chemical modification of reduced graphene oxide (rGO) with sulfonic acid groups produced two solid acids for acid-catalyzed reactions. One of the solid acids was prepared by covalent modification of rGO with oleum to achieve rGO-SO3H. The second solid acid obtained from the reaction of d...
EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) products have been widely applied due to their medical and healthcare value. In this paper, the methods for extracting DHA and EPA from microalgae and related purification methods were summarized and analyzed. The yields of DHA and EPA f...
When a neutral solution of thymidine and ascorbic acid was irradiated with UV light of wavelength longer than 300 nm in the presence of salicylic acid as a photosensitizer, six product peaks appeared in an HPLC chromatogram in addition to small amounts of thymidine dimers. The six products were ...
The monohydrate 1:2 organic salt of 2-Amino-5-bromo-6-methyl-4-pyrimidinol (ABMP), also known as 5-Bromo-6-methylisocytosine, with 2,3-pyrazinedicarboxylic acid (PDCA) has been synthesized by slow evaporation technique. The hydrated salt has been characterized by single crystal X-ray diffraction...
N-Acetylneuraminic acid is a sugar molecule of biological significance due to its pivotal role in molecular recognition processes. The three dimensional structure and conformation of α-Neu5Ac in biological environments can be clearly observed by molecular dynamics (MD) simulation and quantum me...
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View