1.1. An histidine-rich polypeptide has been isolated from the parotid saliva of Macaca nemestrina by column Chromatographic methods and compared to a similar molecule from human parotid saliva.2.2. The fraction has been characterized by amino acid composition, molecular weight, electrophoretic b...

Although salivary gland cancers comprise only ∼3–6% of head and neck cancers, treatment options for patients with advanced-stage disease are limited. Because of their rarity, salivary gland malignancies are understudied compared to other exocrine tissue cancers. The comparative lack of progres...

Balekjian and Longton (1973) suggested the histidine-rich-polypeptides (HRP) in parotid saliva might be nuclear histones. HRP were isolated from parotid saliva of Macaca mulatta. Nuclear histones were prepared from parotid glands and liver of this species. Comparison by amino-acid composition an...

Rabbit and goat antisera to human parotid saliva were examined for the presence of antibodies to human salivary histidine-rich polypeptides (HRP). Antibodies to HRP were present in goat serum but were not detectable in serum from rabbits.

The isolation of an histidine-rich polypeptide from human parotid saliva is described. This polypeptide, termed HRP-1, contains 17% histidine. HRP-1 is a neutral molecule and is a precursor of the cationic histidine-rich polypeptides found in saliva. Results of in vitro saliva incubations sugges...

Incubation of purified synthetic histidine-rich polypeptides, HRP-2, -3, -4, -5, -6 (histatins), with diluted human parotid saliva yielded a series of peptide degradation products whose structures could be determined by gas-phase sequencing of cationic polyacrylamide gel electroblots. Sequencing...

A novel method utilizing high-performance liquid chromatography (HPLC) with evaporative light scattering detection (ELSD) and electrospray ionisation mass spectrometry (ESI-MS) was developed for the analysis of soyasaponins, a divers group of triterpenic compounds with one or two sugar side chai...

A method using high-performance liquid chromatography (HPLC) with electrospray ionization mass spectrometry (ESI-MS) in the negative mode is presented for the quantification and characterization of different soyasaponins using six authentic soyasaponin standards. This method was successfully app...

The amphipathic character of soyasaponins and their consequent biological and technological properties are well-recognised. However, mainly due to the absence of purified compounds, no data are available on the amphiphilic surfactant properties of individual soyasaponins. In this study we develo...

Soyasaponins have been shown to restrict fat absorption in the gut and reduce circulating levels of cholesterol and triacylglycerol. Most of the research in this regard have been performed using whole soyasaponins extract or soyasaponins B. In this study we aim to evaluate the effect of soyasapo...

Immunological adjuvants are agents that enhance specific immune responses to vaccines. At present more studies are needed to identify a suitable adjuvant for a particular vaccine with maximum safety and efficacy. In this study, six soyasaponins (Aa, Ab, Af, Ba, Bb, and Bb′) and three soyasaponi...

Postmenopausal obesity is becoming a serious global health concern. Soyasaponin Ab (SA) inhibits adipocyte differentiation; however, the preventive and therapeutic potential of SA in postmenopausal obesity has not been clearly established. Here, we investigated the anti-obesity effects of SA in ...

Replacement of AcO-3 in methyl 2,3-di-O-acetyl-4-O-trityl-β-d-xylopyranoside with a benzyl group greatly increases the 1,2-trans-stereoselectivity of glycosylation with a d-xylopyranose 1,2-O-(1-cyanoethylidene) derivative. Anomerisation of methyl 2-O-benzyl-β-d-xylopyranoside derivatives occu...

ZusammenfassungDie Darstellung von exo- und endo-Bicyclo[4.2.1]nonen-(2)-ol-(4) (3) und (4) sowie von exo-und endo-Bicyclo[4.2.1]nonanol-(3) und (2) aus 3,3-Dihalotricyclo[4.2.1.02,4]nonyl-Derivaten wird beschrieben. Über die Konfiguration der Allylalkohole 3 und 4 wird die Konfiguration der ge...

1-Octen-3-ol is considered a major contributor to the characteristic mushroom aroma. It has been proposed that in the oyster mushroom Pleurotus ostreatus, 1-octen-3-ol is synthesized through two pathways comprising either 13-hydroperoxy-9Z,11E-octadecadienoic acid (13-HPOD) or 10-hydroperoxy-8E,...

Effective trapping techniques for Cryptolestes ferrugineus are essential for developing an understanding of the ecology of this beetle outside the storage environment, and will assist in monitoring the spread of fumigant resistance in field populations. We evaluated ten different volatile compou...

The purpose of this contribution is to compare the quality of adsorbed films of CH3(CH2)nSiCl3 and CH3(CH2)nPO(OH)2, n=4 and 13. Mechanically polished polycrystalline titanium substrates were reacted with 10−3 M solutions of the compounds in ethanol for the n-alkanephosphonic acids and i...

The reaction of β-keto amides with ethyl(iodomethyl)zinc provides access to a wide variety of γ-keto amides, including primary, secondary, and tertiary amides. Although the reaction of α-substituted β-keto amides are in many cases unsatisfactory, the method can be applied to a broad spectrum...

ESR spectra at both X- and Q-band are reported for Mn(II) ions doped at a nominal 1% in the lattices of [M(DA)2(H2O)2]X2 (M = Mg, Co and Ni; X = Cl or Br), [Mg(DA)2(H2O)2](NO3)2, [Co(DA)4(H2O)2]Br2, M(DA)2Cl2 (M = Mg, Co and Ni) and M(DA)2(NO3)2 (M = Co and Zn). The zero-field splitting paramete...

Fifteen complexes of diacetamide and Group IIB metal salts have been isolated. It was found that HgCl2·2DA, HgBr2·2DA, CdBr2·DA and CdBr2·1·5DA contain diacetamide in the cis-trans dimeric form, whereas ZnCl2·DA, ZnBr2·DA, ZnI2·DA, Zn(NO3)2·2DA, Zn(ClO4)2·3DA, CdI2·DA, Cd(NO3)2·2·5D...