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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

N-Phenyl-isobutyloylacetamide Manufacturer/High quality/Best price/In stock

Cas:124401-38-3

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality Oled CAS 124401-38-3 N-Phenyl-isobutyloylacetamide

Cas:124401-38-3

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

N-Phenylisobutyloylacetamide

Cas:124401-38-3

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

CAS: 842212-02-1 Molecular weight: 197.661 Compound purity: > 99.7% Related substance: Total Impurities(%) ≤ 0.3% Appearance: Crystals IUPAC:1-(4-Chlorophenyl)-2-(methylamino)propan-1-one

4-Methyl-3-oxopentanoic acid anilide

Cas:124401-38-3

Min.Order:1 Gram

FOB Price: $1000.0

Type:Trading Company

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Ality Chemical Corporation

N-Phenyl-isobutyloylacetamide Basic information Product Name: N-Phenyl-isobutyloylacetamide Synonyms: N-PHENYL-ISOBUTYLOYLACETAMIDE;N-PHENYL ISOBUTYRYLACETAMIDE;4-Methyl-3-oxopentanoic acid anilide;4-methyl-3-oxo-n-phenyl-pentanamide;4-methyl-3

Factory Supply N-Phenyl-isobutyloylacetamide

Cas:124401-38-3

Min.Order:1 Gram

Negotiable

Type:Other

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Henan Tianfu Chemical Co., Ltd.

N-Phenyl-isobutyloylacetamide Basic information Product Name: N-Phenyl-isobutyloylacetamide Synonyms: N-PHENYL-ISOBUTYLOYLACETAMIDE;N-PHENYL ISOBUTYRYLACETAMIDE;4-Methyl-3-oxopentano

4-methyl-3-oxo-N-phenyl pentanamide

Cas:124401-38-3

Min.Order:2 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

N-Phenyl-isobutyloylacetamide)

Cas:124401-38-3

Min.Order:1 Kilogram

FOB Price: $100.0 / 150.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 124401-38-3 with best quality

Cas:124401-38-3

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

N-Phenyl-isobutyloylacetamide 124401-38-3

Cas:124401-38-3

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Atorvastatin Intermediates M-2 Chemical Name: 4-methyl-3-oxo-N-phenyl pentanamide Specification: Appearance : Off-white or white crystalline powder CAS No: 124401-38-3 Assay HPLC: 99%min Impurity(By HPLC): 1.0%max Loss on drying: 0.5%

N-Phenyl-isobutyloylacetamide

Cas:124401-38-3

Min.Order:20 Kilogram

FOB Price: $1.0

Type:Other

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White Crystalline Powder Storage:Store in sealed conta

high quality 124401-38-3 N-Phenyl-isobutyloylacetamide with best price

Cas:124401-38-3

Min.Order:10 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

N-Phenyl-isobutyloylacetamide 124401-38-3

Cas:124401-38-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

N-Phenyl-isobutyloylacetamide 99%

Cas:124401-38-3

Min.Order:1 Kilogram

FOB Price: $85.0 / 89.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

N-Phenyl-isobutyloylacetamide CAS:124401-38-3 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality or

N-Phenyl-isobutyloylacetamide CAS:124401-38-3

Cas:124401-38-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

N-Phenyl-isobutyloylacetamide

Cas:124401-38-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Zenuo Biological Medicine Technology Co Ltd

Product Name: N-Phenyl-isobutyloylacetamide Synonyms: N-Phenyl-4-Methyl-3-oxopentanaMide;Intermediates of Atorvastatin Calcium M-2;N-PHENYL-ISOBUTYLOYLACETAMIDE;N-PHENYL ISOBUTYRYLACETAMIDE;4-Methyl-3-oxopentanoic acid anilide;4-methyl-3-oxo-n-ph

Atorvastatin Intermediates N-Phenyl-isobutyloylacetamide Manufactory best quality

Cas:124401-38-3

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

N-Phenyl-isobutyloylacetamide

Cas:124401-38-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

4-Methyl-3-Oxo-N-Phenyl Pentanamide

Cas:124401-38-3

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

N-Phenyl-isobutyloylacetamide

Cas:124401-38-3

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

4-METHYL-3-OXO-N-PHENYLPENTANAMIDE

Cas:124401-38-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

N-Phenyl-isobutyloylacetamide

Cas:124401-38-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

Our advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be

N-Phenyl-isobutyloylacetamide

Cas:124401-38-3

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

N-Phenyl-isobutyloylacetamide/High quality/Best price

Cas:124401-38-3

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 4-Methyl-3-Oxo-N-Phenyl Pentanamide

Cas:124401-38-3

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

N-Phenyl-isobutyloylacetamide

Cas:124401-38-3

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 4-Methyl-3-Oxo-N-Phenyl Pentanamide CAS No.:124401-38-3 Molecule Formula:C12H15NO2 Molecule Weight:205.25 Purity: 99.0% Package: 25kg/drum Description:White crystalline powder Manufacture Standards:Enterprise Standard

Best Quality 4-Methyl-3-Oxo-N-Phenyl Pentanamide

Cas:124401-38-3

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

N-Phenyl-isobutyloylacetamide

Cas:124401-38-3

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd.established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World. Hu

4-methyl-3-oxo-N-phenylpentanamide

Cas:124401-38-3

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

N-Phenyl-isobutyloylacetamide

Cas:124401-38-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

N-Phenyl-isobutyloylacetamide

Cas:124401-38-3

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Synthetic route

Methyl 4-methyl-3-oxopentanoate
42558-54-3

Methyl 4-methyl-3-oxopentanoate

aniline
62-53-3

aniline

4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

Conditions
ConditionsYield
With dmap at 100℃; for 16h;96.4%
With triethylamine at 80 - 125℃;92.7%
With sodium hydroxide In neat (no solvent) at 135℃; for 12h;92%
aniline
62-53-3

aniline

isobutyryl Meldrum's acid

isobutyryl Meldrum's acid

4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

Conditions
ConditionsYield
In toluene Acylation; ring cleavage; Heating;96%
aniline
62-53-3

aniline

ethyl 4-methyl-3-oxo-pentanoate
7152-15-0

ethyl 4-methyl-3-oxo-pentanoate

4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

Conditions
ConditionsYield
With triethylamine In toluene for 4h; Reflux;92%
In toluene for 3h; Reflux;81%
With acetic acid In toluene for 4h; Heating;66%
With pyridine In toluene for 16h; Reflux;
C21H31N3O4
1236069-48-9

C21H31N3O4

4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

Conditions
ConditionsYield
With trifluoroacetic acid In dichloromethane at 20℃; for 0.666667h;88%
ethyl 4-methyl-3-oxo-pentanoate
7152-15-0

ethyl 4-methyl-3-oxo-pentanoate

4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

Conditions
ConditionsYield
With aniline In acetic acid; ethyl acetate; toluene66%
Methyl 4-methyl-3-oxopentanoate
42558-54-3

Methyl 4-methyl-3-oxopentanoate

4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

Conditions
ConditionsYield
With ethylenediamine; aniline In water; toluene
With aniline In water; ethylenediamine; toluene
toluene-water

toluene-water

Methyl 4-methyl-3-oxopentanoate
42558-54-3

Methyl 4-methyl-3-oxopentanoate

A

4-Methyl-3-oxo N phenylpentamide

4-Methyl-3-oxo N phenylpentamide

B

4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

Conditions
ConditionsYield
With ethylenediamine; aniline In water; toluene
toluene-water

toluene-water

Methyl 4-methyl-3-oxopentanoate
42558-54-3

Methyl 4-methyl-3-oxopentanoate

A

4-Methyl-3-oxo-N-phenylpentamide

4-Methyl-3-oxo-N-phenylpentamide

B

4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

Conditions
ConditionsYield
With ethylenediamine; aniline In water; toluene
3-methyl-butan-2-one
563-80-4

3-methyl-butan-2-one

phenyl isocyanate
103-71-9

phenyl isocyanate

4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

Conditions
ConditionsYield
With sodium hydride In toluene; mineral oil Inert atmosphere; Reflux;
3-methyl-butan-2-one
563-80-4

3-methyl-butan-2-one

4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: sodium hydride / 1,4-dioxane; mineral oil / 0.17 h / 20 °C
1.2: 3 h / 50 °C
2.1: triethylamine / toluene / 6 h / 70 - 120 °C
View Scheme
Multi-step reaction with 2 steps
1: potassium tert-butylate / tetrahydrofuran / 8 h / 60 °C / Inert atmosphere
2: ethylenediamine / 5,5-dimethyl-1,3-cyclohexadiene / 4 h / 140 - 150 °C / Inert atmosphere
View Scheme
isobutyrylacetic acid
5650-76-0

isobutyrylacetic acid

aniline
62-53-3

aniline

4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

Conditions
ConditionsYield
With triethylamine In toluene at 85℃; for 4h;67 g
4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

2,2-Difluoro-4-methyl-3-oxo-N-phenylpentanamide
1439365-82-8

2,2-Difluoro-4-methyl-3-oxo-N-phenylpentanamide

Conditions
ConditionsYield
With Selectfluor In water; acetonitrile at 20℃; for 16h; Schlenk technique; Sealed tube; chemoselective reaction;99%
With 1-chloromethyl-4-fluoro-1,4-diazoniabicyclo[2 2 2]octane bis(tetrafluoroborate); potassium carbonate In water at 20℃; for 15h;94%
4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

2-fluoro-4-methyl-3-oxo-N-phenylpentanamide
1026394-65-9

2-fluoro-4-methyl-3-oxo-N-phenylpentanamide

Conditions
ConditionsYield
With Selectfluor In PEG-400 at 60℃; for 17h;96%
With Selectfluor In water; acetonitrile at 20℃; for 4h; Schlenk technique; Sealed tube; chemoselective reaction;94%
4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

C12H16N2O

C12H16N2O

Conditions
ConditionsYield
With ammonium carbamate In methanol at 20℃;96%
4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

benzaldehyde
100-52-7

benzaldehyde

4-methyl-3-oxo-N-phenyl-2-(phenylmethylene)pentanamide
125971-57-5

4-methyl-3-oxo-N-phenyl-2-(phenylmethylene)pentanamide

Conditions
ConditionsYield
With 4-amino-phenol; acetic acid In hexane for 24h; Reflux;94%
With acetic acid; 3-amino propanoic acid In hexane Heating;85%
With ionic tagged amine supported on magneticnanoparticle In water at 80℃; for 4h; Knoevenagel Condensation;84%
4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

benzohydroximoyl chloride
698-16-8

benzohydroximoyl chloride

5-isopropyl-N,3-diphenylisoxazole-4-carboxamide

5-isopropyl-N,3-diphenylisoxazole-4-carboxamide

Conditions
ConditionsYield
With triethylamine; N,N,N',N'-tetramethylguanidine In methanol at 80℃; for 48h; Inert atmosphere;93%
With triethylamine; N,N,N',N'-tetramethylguanidine In methanol at 80℃; for 48h; regioselective reaction;72%
4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

2-bromo-4-methyl-3-oxo-pentanoic acid phenylamide
807361-46-2

2-bromo-4-methyl-3-oxo-pentanoic acid phenylamide

Conditions
ConditionsYield
With N-Bromosuccinimide In acetone for 3h;92%
With bromine In chloroform for 0.5h;80%
4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

N-phenylbenzohydrazonoyl chloride
15424-14-3

N-phenylbenzohydrazonoyl chloride

5-isopropyl-N,1,3-triphenyl-1H-pyrazole-4-carboxamide

5-isopropyl-N,1,3-triphenyl-1H-pyrazole-4-carboxamide

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane at 20℃; for 72h; Inert atmosphere; Green chemistry;92%
With dmap; triethylamine In chloroform at 80℃; for 48h; regioselective reaction;92%
4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

benzaldehyde
100-52-7

benzaldehyde

4-Methyl-3-oxo-N-phenyl-2(phenylmethylene)pentanamide
222320-29-8

4-Methyl-3-oxo-N-phenyl-2(phenylmethylene)pentanamide

Conditions
ConditionsYield
With acetic acid; 3-amino propanoic acid In hexane Heating;90%
With acetic acid In toluene
4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

2-diazo-5-methylcyclohexane-1,3-dione
158836-48-7

2-diazo-5-methylcyclohexane-1,3-dione

(E)-3-(1-hydroxy-2-methylpropylidene)-6-methyl-3,5,6,7-tetrahydrobenzofuran-2,4-dione

(E)-3-(1-hydroxy-2-methylpropylidene)-6-methyl-3,5,6,7-tetrahydrobenzofuran-2,4-dione

Conditions
ConditionsYield
With silver hexafluoroantimonate; [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; acetic acid In 1,2-dichloro-ethane at 70℃; for 4h; Inert atmosphere; chemoselective reaction;90%
diazodimedone
1807-68-7

diazodimedone

4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

(E)-3-(1-hydroxy-2-methylpropylidene)-6,6-dimethyl-3,5,6,7-tetrahydrobenzofuran-2,4-dione

(E)-3-(1-hydroxy-2-methylpropylidene)-6,6-dimethyl-3,5,6,7-tetrahydrobenzofuran-2,4-dione

Conditions
ConditionsYield
With silver hexafluoroantimonate; [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; acetic acid In 1,2-dichloro-ethane at 70℃; for 4h; Inert atmosphere; chemoselective reaction;89%
4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

benzaldehyde
100-52-7

benzaldehyde

4-methyl-3-oxo-N-phenyl-2-(phenylmethylene) pentanamide
222320-17-4

4-methyl-3-oxo-N-phenyl-2-(phenylmethylene) pentanamide

Conditions
ConditionsYield
With amine functionalized silica coated Fe3O4 nanoparticles In water at 20℃; for 0.416667h; Knoevenagel Condensation; Sonication; Green chemistry;87%
With acetic acid; 3-amino propanoic acid In toluene at 130℃; for 12h;29.18%
4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

2,6-di-tert-butyl-4-(2-hydroxybenzylidene)-2,5-cyclohexadiene-1-one

2,6-di-tert-butyl-4-(2-hydroxybenzylidene)-2,5-cyclohexadiene-1-one

C33H43NO4

C33H43NO4

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 20℃; for 48h; Inert atmosphere;87%
3-Phenyl-2-propyn-1-ol
1504-58-1

3-Phenyl-2-propyn-1-ol

4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

3-iso-butyryl-1,4-diphenyl-2-pyridone
1416150-78-1

3-iso-butyryl-1,4-diphenyl-2-pyridone

Conditions
ConditionsYield
With 2-tert-butylimino-2-diethylamino-1,3-dimethylperhydro-1,3,2-diazaphosphorine; ruthenium(IV) oxide hydrate; oxygen In tetrahydrofuran under 760.051 Torr; for 12h; Reflux; regioselective reaction;86%
4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

2-diazo-5-furan-2-yl-cyclohexane-1,3-dione

2-diazo-5-furan-2-yl-cyclohexane-1,3-dione

(E)-6-(furan-2-yl)-3-(1-hydroxy-2-methylpropylidene)-3,5,6,7-tetrahydrobenzofuran-2,4-dione

(E)-6-(furan-2-yl)-3-(1-hydroxy-2-methylpropylidene)-3,5,6,7-tetrahydrobenzofuran-2,4-dione

Conditions
ConditionsYield
With silver hexafluoroantimonate; [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; acetic acid In 1,2-dichloro-ethane at 70℃; for 4h; Inert atmosphere; chemoselective reaction;86%
4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

cyclohexylamine
108-91-8

cyclohexylamine

3-(cyclohexylamino)-4-methylpent-2(E)-enoic acid anilide
124401-40-7

3-(cyclohexylamino)-4-methylpent-2(E)-enoic acid anilide

Conditions
ConditionsYield
With acetic acid In toluene for 20h; Heating;82%
4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

1-(4-fluoro-phenyl)-2-hydroxy-2-phenylethanone
88522-72-9

1-(4-fluoro-phenyl)-2-hydroxy-2-phenylethanone

5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide

5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide

Conditions
ConditionsYield
With ammonium acetate In acetic acid at 110 - 120℃; for 2h;81%
2-bromo-1-(4-fluorophenyl)-2-phenylethan-1-one
88675-31-4

2-bromo-1-(4-fluorophenyl)-2-phenylethan-1-one

4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

A

1-(4-fluorophenyl)-2-phenylethanone
347-84-2

1-(4-fluorophenyl)-2-phenylethanone

B

2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxopentanoic acid phenylamide
125971-96-2

2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxopentanoic acid phenylamide

Conditions
ConditionsYield
With potassium carbonate In acetone at 20℃; for 5h; Reagent/catalyst; Time; Darkness;A n/a
B 80%
2-bromo-1-(4-fluorophenyl)-2-phenylethan-1-one
88675-31-4

2-bromo-1-(4-fluorophenyl)-2-phenylethan-1-one

4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxopentanoic acid phenylamide
125971-96-2

2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxopentanoic acid phenylamide

Conditions
ConditionsYield
With potassium carbonate In acetone for 2h; Reflux;78%
With potassium carbonate In acetone at 18.5 - 26℃; Product distribution / selectivity;77.7%
With potassium carbonate In acetone at 18 - 26℃;74%
(2-nitroethenyl)benzene
102-96-5

(2-nitroethenyl)benzene

4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

aniline
62-53-3

aniline

2-isopropyl-N,1,4-triphenyl-1H-pyrrole-3-carboxamide

2-isopropyl-N,1,4-triphenyl-1H-pyrrole-3-carboxamide

Conditions
ConditionsYield
With zirconocene dichloride In ethanol at 80℃; for 1.5h;75%
4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

propargyl alcohol
107-19-7

propargyl alcohol

2-isopropyl-4-methyl-N-phenylfuran-3-carboxamide

2-isopropyl-4-methyl-N-phenylfuran-3-carboxamide

Conditions
ConditionsYield
With triethylamine; silver carbonate In acetonitrile at 80℃; for 12h; Inert atmosphere; Molecular sieve; regioselective reaction;75%
2-chloro-1-(4-fluorophenyl)-2-phenylethan-1-one
62148-67-8

2-chloro-1-(4-fluorophenyl)-2-phenylethan-1-one

4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxopentanoic acid phenylamide
125971-96-2

2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxopentanoic acid phenylamide

Conditions
ConditionsYield
With potassium carbonate In acetone at 25 - 60℃; Reflux;74%
4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

benzalacetophenone
94-41-7

benzalacetophenone

2-isopropyl-N,4,6-triphenylnicotinamide
1398101-64-8

2-isopropyl-N,4,6-triphenylnicotinamide

Conditions
ConditionsYield
With ammonium cerium (IV) nitrate; ammonium acetate In ethanol at 50℃; for 24h;74%
4-fluoro-β-nitrostyrene
5153-69-5, 706-08-1

4-fluoro-β-nitrostyrene

4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

aniline
62-53-3

aniline

4-(4-fluorophenyl)-2-isopropyl-N,1-diphenyl-1H-pyrrole-3-carboxamide
122223-62-5

4-(4-fluorophenyl)-2-isopropyl-N,1-diphenyl-1H-pyrrole-3-carboxamide

Conditions
ConditionsYield
With zirconocene dichloride In ethanol at 80℃; for 1.5h;74%
4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

2,6-di-tert-butyl-4-(2-hydroxybenzylidene)-2,5-cyclohexadiene-1-one

2,6-di-tert-butyl-4-(2-hydroxybenzylidene)-2,5-cyclohexadiene-1-one

C33H39NO3

C33H39NO3

Conditions
ConditionsYield
Stage #1: 4-methyl-3-oxo-N-phenylpentanamide; 2,6-di-tert-butyl-4-(2-hydroxybenzylidene)cyclohex-2,5-diene-1-one With 3-((3,5-bis(trifluoromethyl)phenyl)amino)-4-(((S)-(6-methoxyquinoline-4-yl))((1S,2S,4S,5R-5-vinylquinuclidine-2-yl)methyl)amino)cyclobutan-3-ene-1,2-dione In dichloromethane at 20℃; for 72h;
Stage #2: With toluene-4-sulfonic acid In toluene at 110℃; for 1h; enantioselective reaction;
74%
4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxopentanoic acid phenylamide
125971-96-2

2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxopentanoic acid phenylamide

Conditions
ConditionsYield
With potassium carbonate In isopropyl alcohol at 10 - 45℃; Product distribution / selectivity;73%
Multi-step reaction with 2 steps
1: β-alanine; glacial acetic acid / hexane / Heating
2: 3-ethyl-5-(2-hydroxyethyl)-4-methylthiazolium bromide; triethylamine / ethanol / Heating
View Scheme
Multi-step reaction with 2 steps
1.1: acetic acid; 4-amino-phenol / hexane / 24 h / Reflux
2.1: triethylamine; 3-ethyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazolium bromide / neat (no solvent) / 16 h / 75 °C / Inert atmosphere
2.2: 4 h / 25 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: glycine; acetic acid / n-heptane / 8 h / Inert atmosphere; Reflux
2: 10 h / 20 °C / Inert atmosphere
View Scheme
4-methyl-β-nitrostyrene
7559-36-6

4-methyl-β-nitrostyrene

4-methyl-3-oxo-N-phenylpentanamide
124401-38-3

4-methyl-3-oxo-N-phenylpentanamide

aniline
62-53-3

aniline

2-isopropyl-N,1-diphenyl-4-p-tolyl-1H-pyrrole-3-carboxamide

2-isopropyl-N,1-diphenyl-4-p-tolyl-1H-pyrrole-3-carboxamide

Conditions
ConditionsYield
With zirconocene dichloride In ethanol at 80℃; for 1.5h;73%
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