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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

2-Thiopheneacetic acid/ LIDE PHARMA- Factory supply / Best price

Cas:1918-77-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

2-Thiopheneacetic acid Manufacturer/High quality/Best price/In stock

Cas:1918-77-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2-Thiophene Acetic Acid supplier in China

Cas:1918-77-0

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Wuhan Fortuna Chemical Co.,Ltd

2-Thiopheneacetic acid CAS 1918-77-0 Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals in dis

2-Thiopheneacetic acid CAS 1918-77-0

Cas:1918-77-0

Min.Order:1 Kilogram

FOB Price: $10.0

Type:Trading Company

inquiry

Henan Allgreen Chemical Co.,Ltd

Good quality Good price Appearance:powder Storage:dry condition Package:According to the demand of customer Application:intermediate Transportation:By sea or by air Port:Shanghai Port

1918-77-0, 2-Thiopheneacetic acid

Cas:1918-77-0

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2-thienylacetic acid

Cas:1918-77-0

Min.Order:1

Negotiable

Type:Other

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-Thiopheneacetic acid

Cas:1918-77-0

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com/pro01en/id/1136.html Product Name 2-Thiopheneacetic acid CAS No. 1918-77-0

2-Thiopheneacetic acid

Cas:1918-77-0

Min.Order:1 Gram

FOB Price: $55.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

1918-77-0 2-Thiopheneacetic acid

Cas:1918-77-0

Min.Order:1 Kilogram

FOB Price: $1000.0

Type:Lab/Research institutions

inquiry

Leader Biochemical Group

About Product Details

China Biggest factory Supply High Quality 2-Thiopheneacetic acid CAS 1918-77-0

Cas:1918-77-0

Min.Order:1 Kilogram

FOB Price: $1.0 / 5.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

top quality 2-Thiopheneacetic acid

Cas:1918-77-0

Min.Order:1 Kilogram

FOB Price: $100.0 / 150.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 1918-77-0 with best quality

Cas:1918-77-0

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Item Specification Product Name 2-Thiopheneacetic acid CAS No. 1918-77-0 Appearance White crystalline powder Content 99% min Appe

2-Thiopheneacetic acid CAS: 1918-77-0

Cas:1918-77-0

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2-Thiopheneacetic acid 1918-77-0

Cas:1918-77-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

2-Thiopheneacetic acid Basic information Product Name: 2-Thiopheneacetic acid Synonyms: Thiophene-2-acetic acid, 98+%;2-THIOPHENE-2-ACETIC ACID;2-Thiophene;2-(Thien-2-yl)acetic acid 97%;2-THIOPHENEACETIC ACID;2-THIENYLACETIC ACID;2-THENYLACETIC

2-Thiopheneacetic acid

Cas:1918-77-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

2-Thiopheneacetic acid CAS:1918-77-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic int

2-Thiopheneacetic acid CAS:1918-77-0

Cas:1918-77-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2-Thiopheneacetic acid

Cas:1918-77-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2-Thiopheneacetic acid

Cas:1918-77-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Appearance:white or light yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:By

2-Thiophene acetic acid

Cas:1918-77-0

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2-Thiopheneacetic acid

Cas:1918-77-0

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

2-THIOPHENEACETIC ACID

Cas:1918-77-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2-Thiophene-2-acetic acid

Cas:1918-77-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

2-Thiopheneacetic acid

Cas:1918-77-0

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

2-Thiofenacetic acid

Cas:1918-77-0

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 2-Thiophene Acetic Acid

Cas:1918-77-0

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

2-Thiopheneacetic acid

Cas:1918-77-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 2-Thiopheneacetic Acid CAS No.:1918-77-0 Molecule Formula:C6H6O2S Molecule Weight:142.18 Purity: 99% Package: 25kg/drum Description:White crystalline powder Manufacture Standards:Enterprise Standard TESTING ITEMS

High Quality 2-Thiopheneacetic Acid in stock

Cas:1918-77-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

2-Thiopheneaceticacid

Cas:1918-77-0

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

2-Thiopheneacetic acid

Cas:1918-77-0

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

2-Thiopheneacetic acid

Cas:1918-77-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

ethyl thiophen-2-ylacetate
57382-97-5

ethyl thiophen-2-ylacetate

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

Conditions
ConditionsYield
With water; sodium hydroxide In ethanol at 20℃; for 1h;100%
With water; sodium hydroxide In ethanol at 20℃; for 1h;100%
2-thiophenethanol
5402-55-1

2-thiophenethanol

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

Conditions
ConditionsYield
With oxygen; triethylamine at 80℃; for 15h; Reagent/catalyst; Temperature;96.5%
With Iron(III) nitrate nonahydrate; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; potassium chloride; oxygen In 1,2-dichloro-ethane at 25℃; for 12h;85%
With sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical In aq. phosphate buffer; water; acetonitrile at 35℃; for 6h; Catalytic behavior; Reagent/catalyst; Temperature; Green chemistry;85%
With iridium hexafluoride; sulphate-doped anatase; potassium oxide In dichloromethane at 85℃; Temperature;
methyl 2-thiopheneacetate
19432-68-9

methyl 2-thiopheneacetate

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

Conditions
ConditionsYield
With sodium hydroxide for 2h; Heating;94%
2,2,2-trichloro-1-(thien-2-yl)-ethanol
35320-27-5

2,2,2-trichloro-1-(thien-2-yl)-ethanol

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

Conditions
ConditionsYield
Stage #1: 2,2,2-trichloro-1-(thien-2-yl)-ethanol With sodium tetrahydroborate; diphenyl diselenide In ethanol Inert atmosphere;
Stage #2: With sodium hydroxide In ethanol at 40℃; Inert atmosphere;
94%
2-cyanomethylthiophene
20893-30-5

2-cyanomethylthiophene

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

Conditions
ConditionsYield
With sodium hydroxide In water for 5h; Reflux;93.4%
With water; potassium hydroxide In ethanol for 3h; Inert atmosphere; Reflux;74%
With potassium hydroxide
N-((E)-1-Cyano-2-thiophen-2-yl-vinyl)-4,N-dimethyl-benzamide
89244-23-5, 89244-24-6

N-((E)-1-Cyano-2-thiophen-2-yl-vinyl)-4,N-dimethyl-benzamide

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

Conditions
ConditionsYield
With hydrogenchloride In tetrahydrofuran for 6h; Heating;89%
2-methoxy-2-(thiophen-2-yl)acetic acid
5371-94-8

2-methoxy-2-(thiophen-2-yl)acetic acid

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

Conditions
ConditionsYield
With sodium chloride; iodine In water; acetic acid; ethyl acetate86%
α-(N-Methylanilino)-β-(2-thienyl)acrylonitrile
91668-56-3

α-(N-Methylanilino)-β-(2-thienyl)acrylonitrile

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

Conditions
ConditionsYield
With hydrogenchloride In tetrahydrofuran for 10h; Heating;83%
2-oxo-3-(thiophen-2-yl)propanoic acid
15504-41-3

2-oxo-3-(thiophen-2-yl)propanoic acid

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

Conditions
ConditionsYield
With sodium perborate In water for 48h; Ambient temperature;68%
thiophene-2-carbaldehyde
98-03-3

thiophene-2-carbaldehyde

Bromoform
75-25-2

Bromoform

ethanethiol
75-08-1

ethanethiol

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

Conditions
ConditionsYield
With potassium hydroxide In diethyl ether; water; dimethyl sulfoxide58%
carbon dioxide
124-38-9

carbon dioxide

N,N,N-trimethyl-1-(thiophen-2-yl)methanaminium trifluoromethanesulfonate

N,N,N-trimethyl-1-(thiophen-2-yl)methanaminium trifluoromethanesulfonate

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

Conditions
ConditionsYield
With (4,4'-di-tert-butyl-2,2'-dipyridyl)-bis-(2-phenylpyridine(-1H))-iridium(III) hexafluorophosphate; sodium carbonate; caesium carbonate In N,N-dimethyl-formamide at 25 - 30℃; for 36h; Schlenk technique; Glovebox; Sealed tube; Irradiation;55%
((Z)-1-Dimethylamino-2-thiophen-2-yl-vinyl)-phosphonic acid diethyl ester
82670-75-5

((Z)-1-Dimethylamino-2-thiophen-2-yl-vinyl)-phosphonic acid diethyl ester

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

Conditions
ConditionsYield
With hydrogenchloride Heating;43%
carbon monoxide
201230-82-2

carbon monoxide

2-thiophenemethanol
636-72-6

2-thiophenemethanol

A

2-Methylthiophene
554-14-3

2-Methylthiophene

B

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

Conditions
ConditionsYield
With hydrogen iodide; tetrakis(triphenylphosphine) palladium(0) In acetone at 90℃; under 68400 Torr; for 42h; Carbonylation; reduction;A 12%
B 18%
2-Thiophenecarbonyl chloride
5271-67-0

2-Thiophenecarbonyl chloride

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

Conditions
ConditionsYield
With diethyl ether Erwaermen einer Loesung des Reaktionsprodukts in Dioxan mit Silberoxid und Natriumthiosulfat in Wasser;
2-Chloromethylthiophene
765-50-4

2-Chloromethylthiophene

A

2-methylthiophene-3-carboxylic acid
1918-78-1

2-methylthiophene-3-carboxylic acid

B

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

Conditions
ConditionsYield
With diethyl ether; magnesium Behandeln des Reaktionsgemisches mit festem Kohlendioxid;
2-Acetylthiophene
88-15-3

2-Acetylthiophene

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

Conditions
ConditionsYield
With 1,4-dioxane; ammonium polysulfide solution; sulfur Erhitzen des erhaltenen Saeureamids mit wss. Kalilauge;
With 1,4-dioxane; ammonium polysulfide solution; sulfur Erhitzen des erhaltenen Saeureamids mit wss. Salzsaeure;
Multi-step reaction with 2 steps
1: 83 percent / BF3*O(C2H5)3, Pb(OAc)4 / benzene / 11 h / Ambient temperature
2: 94 percent / aq. NaOH / 2 h / Heating
View Scheme
2-thenyl magnesium chloride
19432-64-5

2-thenyl magnesium chloride

methylammonium carbonate
15719-64-9, 15719-76-3, 97762-63-5

methylammonium carbonate

A

2-methylthiophene-3-carboxylic acid
1918-78-1

2-methylthiophene-3-carboxylic acid

B

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

isopropyl 2-(thiophen-2-yl)acetate
68100-13-0

isopropyl 2-(thiophen-2-yl)acetate

A

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

B

propene
187737-37-7

propene

Conditions
ConditionsYield
In gaseous matrix at 326.9℃; gas-phase Hammett replacement ς0 substituent constant was investigated;
tert-butyl 2-(thiophen-2-yl)acetate
58416-18-5

tert-butyl 2-(thiophen-2-yl)acetate

A

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

B

isobutene
115-11-7

isobutene

Conditions
ConditionsYield
In gaseous matrix at 326.9℃; gas-phase Hammett replacement ς0 substituent constant was investigated;
α-thienylglycolic acid

α-thienylglycolic acid

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

Conditions
ConditionsYield
With phosphorus; hydrogen iodide
methylammonium carbonate
15719-64-9, 15719-76-3, 97762-63-5

methylammonium carbonate

<2>thienyl-methyl magnesium chloride

<2>thienyl-methyl magnesium chloride

A

2-methylthiophene-3-carboxylic acid
1918-78-1

2-methylthiophene-3-carboxylic acid

B

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

Conditions
ConditionsYield
With diethyl ether
2-diazo-1-(thiophen-2-yl)ethanone
72676-21-2

2-diazo-1-(thiophen-2-yl)ethanone

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

Conditions
ConditionsYield
With silver(l) oxide In 1,4-dioxane Rearrangement;
2-Thiophenecarbonyl chloride
5271-67-0

2-Thiophenecarbonyl chloride

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: diethyl ether / 0 °C
2: aq. Ag2O / dioxane
View Scheme
Multi-step reaction with 2 steps
1: diethyl ether / Erwaermen des Reaktionsprodukts mit Silberoxid und Methanol
View Scheme
2-thiophenylcarboxylic acid
527-72-0

2-thiophenylcarboxylic acid

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: (COCl)2; DMF / CH2Cl2
2: diethyl ether / 0 °C
3: aq. Ag2O / dioxane
View Scheme
thiophene-2-carbaldehyde
98-03-3

thiophene-2-carbaldehyde

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 68 percent / KH / tetrahydrofuran / 4 h / Ambient temperature
2: 83 percent / 10percent aq. HCl / tetrahydrofuran / 10 h / Heating
View Scheme
2-ethynyl-thiophene
4298-52-6

2-ethynyl-thiophene

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: benzene, NaHCO3 / methanol / 110 h / Heating
2: 2N NaOH
View Scheme
Multi-step reaction with 2 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Inert atmosphere
1.2: 2 h / -78 °C / Inert atmosphere
2.1: oxone||potassium monopersulfate triple salt; water / acetone / 12 h / 50 °C / Inert atmosphere
View Scheme
3-thiophen-2-yl-2-thioxo-propionic acid
89677-36-1

3-thiophen-2-yl-2-thioxo-propionic acid

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: ethanol; hydroxylamine
2: acetic acid anhydride
3: aq.-ethanolic KOH-solution
View Scheme
5-(2'-thiophenemethylene)rhodamine
6319-47-7, 98800-08-9, 98800-09-0

5-(2'-thiophenemethylene)rhodamine

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: aq. NaOH solution
2: ethanol; hydroxylamine
3: acetic acid anhydride
4: aq.-ethanolic KOH-solution
View Scheme
methanol
67-56-1

methanol

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

methyl 2-thiopheneacetate
19432-68-9

methyl 2-thiopheneacetate

Conditions
ConditionsYield
With hydrogenchloride for 3h; Heating;100%
With thionyl chloride at 0 - 20℃; for 18h;100%
With thionyl chloride at 0 - 20℃; for 18h;100%
Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

5,6-dimethoxy-2-(N-propylamino)indan
162751-96-4

5,6-dimethoxy-2-(N-propylamino)indan

N-(5,6-dimethoxy-indan-2-yl)-N-propyl-2-thiophen-2-yl-acetamide
745060-18-8

N-(5,6-dimethoxy-indan-2-yl)-N-propyl-2-thiophen-2-yl-acetamide

Conditions
ConditionsYield
With diethyl cyanophosphonate; triethylamine In dichloromethane at 20℃; for 24h;100%
Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

benzylamine
100-46-9

benzylamine

N-benzyl-2-(thiophen-2-yl)acetamide

N-benzyl-2-(thiophen-2-yl)acetamide

Conditions
ConditionsYield
With (2-(thiophen-2-ylmethyl)phenyl)boronic acid In dichloromethane at 20℃; for 24h; Inert atmosphere; Molecular sieve;99%
With bis(cyclopentadienyl)titanium dichloride In tetrahydrofuran at 70℃; for 24h; Molecular sieve; Sealed tube; Inert atmosphere;90%
Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

oxalyl dichloride
79-37-8

oxalyl dichloride

2-(2'-Thienyl)methyl-penem-3-carboxylic Acid

2-(2'-Thienyl)methyl-penem-3-carboxylic Acid

Conditions
ConditionsYield
98.8%
Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

4'-methoxy-N-(azulen-1-ylmethylene)aniline
854154-95-3

4'-methoxy-N-(azulen-1-ylmethylene)aniline

1-(azulen-1'-yl)-2-(thien-2''-yl)ethene
652142-07-9

1-(azulen-1'-yl)-2-(thien-2''-yl)ethene

Conditions
ConditionsYield
for 0.25h; Heating;98%
for 0.5h; Heating;98%
hydrogenchloride
7647-01-0

hydrogenchloride

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

lead(II) nitrate

lead(II) nitrate

potassium hydroxide

potassium hydroxide

[Pb(thiophene-2-acetate)2(H2O)]n

[Pb(thiophene-2-acetate)2(H2O)]n

Conditions
ConditionsYield
Stage #1: hydrogenchloride; lead(II) nitrate; potassium hydroxide at 70℃; for 0.5h; Green chemistry;
Stage #2: Thiophene-2-acetic acid for 6h; Heating; Green chemistry;
98%
Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

aniline
62-53-3

aniline

N-phenyl-2-(thiophen-2-yl)acetamide
69047-40-1

N-phenyl-2-(thiophen-2-yl)acetamide

Conditions
ConditionsYield
With triethylamine; Phenyl N-phenylphosphoramidochloridate In dichloromethane for 1h; Ambient temperature;97%
With zeolite-HY In neat (no solvent) for 1h; Irradiation;97%
With N,N-bis[2-oxo-3-oxazolidinyl]phosphorodiamidic chloride; triethylamine In dichloromethane at 20 - 25℃; for 1h;90%
Stage #1: Thiophene-2-acetic acid With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane at 20℃; for 1h;
Stage #2: aniline In tetrahydrofuran at 20℃; for 2h;
81%
Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

2-thiophenethanol
5402-55-1

2-thiophenethanol

Conditions
ConditionsYield
With dimethylsulfide borane complex In tetrahydrofuran at 0 - 20℃; for 6h;97%
With tricarbonyl(η(4)-cycloocta-1,5-diene)iron; phenylsilane In tetrahydrofuran at 20℃; for 24h; Inert atmosphere; UV-irradiation; chemoselective reaction;95%
With indium(III) bromide; 1,1,3,3-Tetramethyldisiloxane In chloroform at 60℃; for 2h; Inert atmosphere;73%
Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

phenyl isocyanate
1197040-29-1

phenyl isocyanate

N-formyl-N-phenyl-2-(thiophen-2-yl)acetamide
1414349-67-9

N-formyl-N-phenyl-2-(thiophen-2-yl)acetamide

Conditions
ConditionsYield
In toluene at 110℃; Sealed tube; Inert atmosphere;97%
Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

4-Methoxyphenethylamine
55-81-2

4-Methoxyphenethylamine

N-(2-(4-methoxyphenyl)ethyl)-2-thiophen-2-ylacetamide
349433-11-0

N-(2-(4-methoxyphenyl)ethyl)-2-thiophen-2-ylacetamide

Conditions
ConditionsYield
With benzotriazol-1-ol; dicyclohexyl-carbodiimide In tetrahydrofuran at 20℃;97%
Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

silver nitrate

silver nitrate

silver(I) 2-thiopheneacetate

silver(I) 2-thiopheneacetate

Conditions
ConditionsYield
With triethylamine In ethanol; acetonitrile at 0℃; for 2h; Inert atmosphere; Schlenk technique;97%
With triethylamine In ethanol; acetonitrile at 0℃; for 2h;97%
Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

diethyl 4-(6-hydroxyhexan-2-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

diethyl 4-(6-hydroxyhexan-2-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

diethyl 2,6-dimethyl-4-(6-(2-(thiophen-2-yl)acetoxy)hexan-2-yl)-1,4-dihydropyridine-3,5-dicarboxylate

diethyl 2,6-dimethyl-4-(6-(2-(thiophen-2-yl)acetoxy)hexan-2-yl)-1,4-dihydropyridine-3,5-dicarboxylate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 2h;97%
Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

o-toluidine
95-53-4

o-toluidine

2-(thiophen-2-yl)-N-(o-tolyl)acetamide
69047-43-4

2-(thiophen-2-yl)-N-(o-tolyl)acetamide

Conditions
ConditionsYield
With N,N-bis[2-oxo-3-oxazolidinyl]phosphorodiamidic chloride; triethylamine In dichloromethane at 20 - 25℃; for 1h;96%
Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

trimethylsilyl 2-(thien-2-yl)acetate
934415-23-3

trimethylsilyl 2-(thien-2-yl)acetate

Conditions
ConditionsYield
Stage #1: Thiophene-2-acetic acid With pyridine In tetrahydrofuran at 0℃; for 0.5h;
Stage #2: chloro-trimethyl-silane With 1,1,1,3,3,3-hexamethyl-disilazane In tetrahydrofuran at 0 - 20℃; for 12h;
96%
piperidine
110-89-4

piperidine

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

1-(piperidin-1-yl)-2-(thiophen-2-yl)ethan-1-one
114373-80-7

1-(piperidin-1-yl)-2-(thiophen-2-yl)ethan-1-one

Conditions
ConditionsYield
With tris(2,2,2-trifluoroethyl) borate for 24h; Dean-Stark; Reflux;96%
With zirconium(IV) chloride In tetrahydrofuran at 70℃; for 24h; Molecular sieve; Inert atmosphere;78%
morpholine
110-91-8

morpholine

Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

1-morpholino-2-(thiophen-2-yl)ethan-1-one

1-morpholino-2-(thiophen-2-yl)ethan-1-one

Conditions
ConditionsYield
With phenylsilane In acetonitrile at 20℃; for 2.5h;96%
Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

ethanol
64-17-5

ethanol

ethyl thiophen-2-ylacetate
57382-97-5

ethyl thiophen-2-ylacetate

Conditions
ConditionsYield
With hydrogenchloride In water at 70℃; for 19h;95%
With hydrogenchloride In water at 20 - 70℃; for 19h;95%
With sulfuric acid Reflux;71%
Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

tantalum pentaethoxide
150747-55-0

tantalum pentaethoxide

[Ta(OC2H5)3(C4H3SCH2COO)2]
98605-57-3

[Ta(OC2H5)3(C4H3SCH2COO)2]

Conditions
ConditionsYield
In benzene byproducts: C2H5OH; react. under anhydrous conditions, addn. of 2-thiopheneacetic acid to asoln. of Ta(OEt)5 in benzene (2:1 molar ratio), refluxing for 8 h; collecting of liberated ethanol azeotropically, distg. off excess solvent, drying in vac., elem. anal.;95%
Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

4-Bromo-benzene-1,2-diamine
1575-37-7

4-Bromo-benzene-1,2-diamine

6-bromo-2-(thiophen-2-ylmethyl)-1H-benzo[d]imidazole
1340048-81-8

6-bromo-2-(thiophen-2-ylmethyl)-1H-benzo[d]imidazole

Conditions
ConditionsYield
Stage #1: Thiophene-2-acetic acid With borane-THF In tetrahydrofuran; toluene at 20℃; for 0.5h; Cooling with ice;
Stage #2: 4-Bromo-benzene-1,2-diamine In tetrahydrofuran; toluene for 12h; Reflux;
95%
Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

Cyclohexyl isocyanide
931-53-3

Cyclohexyl isocyanide

(Z)-3-(cyclohexylamino)-3-oxo-1-(thiophen-2-yl)prop-1-en-2-yl 2-(thiophen-2-yl)acetate
1414349-77-1

(Z)-3-(cyclohexylamino)-3-oxo-1-(thiophen-2-yl)prop-1-en-2-yl 2-(thiophen-2-yl)acetate

Conditions
ConditionsYield
In nitromethane at 40℃; for 24h; Solvent; Concentration; Temperature; Sealed tube;95%
Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

3,4-methylenedioxyphenylethylamine
1484-85-1

3,4-methylenedioxyphenylethylamine

N-(2-(benzo[d][1,3]dioxol-5-yl)ethyl)-2-(thiophen-2-yl)acetamide
92851-34-8

N-(2-(benzo[d][1,3]dioxol-5-yl)ethyl)-2-(thiophen-2-yl)acetamide

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane at 20℃; for 6h;95%
With benzotriazol-1-ol; dicyclohexyl-carbodiimide In tetrahydrofuran at 20℃;74%
Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

thiophene-2-carbaldehyde
98-03-3

thiophene-2-carbaldehyde

Conditions
ConditionsYield
With potassium carbonate In chloroform at 20℃; for 24h; Irradiation; Inert atmosphere;95%
With dipotassium peroxodisulfate In water at 90℃; for 12h; Green chemistry;75%
With oxygen; copper diacetate In dimethyl sulfoxide at 120℃; for 18h; Sealed tube;72%
Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

hexachloro[60]fullerene
151013-83-1

hexachloro[60]fullerene

C90H25ClO10S5

C90H25ClO10S5

Conditions
ConditionsYield
With tin(IV) chloride In 1,2-dichloro-benzene at 70 - 80℃; for 1h; Inert atmosphere;95%
Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

2-thienylacetic acid chloride
39098-97-0

2-thienylacetic acid chloride

Conditions
ConditionsYield
With bis(trichloromethyl) carbonate; N,N-dimethyl-formamide In dichloromethane at -10 - 0℃; for 5h; Temperature; Reagent/catalyst;94.7%
With phosgene; 4-cyclopentylaminopyridine hydrobromide In toluene92%
With 1-butyl-3-methylimidazolium hydroxide; thionyl chloride In chloroform at 10℃; for 8h; Reagent/catalyst; Temperature;89.8%
Thiophene-2-acetic acid
1918-77-0

Thiophene-2-acetic acid

(6R,7R)-7-Amino-3-(4,4-dimethyl-5-methylsulfanyl-4H-imidazol-2-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
124876-28-4

(6R,7R)-7-Amino-3-(4,4-dimethyl-5-methylsulfanyl-4H-imidazol-2-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R)-3-(4,4-Dimethyl-5-methylsulfanyl-4H-imidazol-2-ylsulfanylmethyl)-8-oxo-7-(2-thiophen-2-yl-acetylamino)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
124876-32-0

(6R,7R)-3-(4,4-Dimethyl-5-methylsulfanyl-4H-imidazol-2-ylsulfanylmethyl)-8-oxo-7-(2-thiophen-2-yl-acetylamino)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Conditions
ConditionsYield
With N,N-bis(trimethylsilyl)acetamide; trichlorophosphate In ethyl acetate; N,N-dimethyl-formamide Ambient temperature;94%

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