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Wuhan Zenuo Biological Medicine Technology Co Ltd

Strict quality control: good raw materials, good quality, Zenuo Biology has always regarded quality as the life of the enterprise. Zenuo Biology has an independent quality control department and long-term cooperation with the third-party detect

Flumethasone Manufactuered in China

Cas:2135-17-3

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

Flumethasone

Cas:2135-17-3

Min.Order:1 Kilogram

Negotiable

Type:Other

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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

Flumethasone Manufacturer/High quality/Best price/In stock

Cas:2135-17-3

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Sinoway Industrial Co., Ltd.

Our advantage Flumethasone--we provide high quality 99% and competitive price. (1)27 year experience in pharmaceutical industry (2)ISO9001:2008 certificated company (3)Fischer Chemicals AG China office Basic information Flumethason

Flumethasone

Cas:2135-17-3

Min.Order:100 Gram

Negotiable

Type:Trading Company

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Flumetazone supplier in China

Cas:2135-17-3

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Kono Chem Co.,Ltd

Brief Description CAS:2135-17-3 MF:C22H28F2O5 MW:410.4515 EINECS:218-370-0 Assay:99% Competitive price with high quality Conforms to BP/USP/EP/FCC flumethasone COA

CAS:2135-17-3 Flumethasone lower price

Cas:2135-17-3

Min.Order:1 Kilogram

Negotiable

Type:Other

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Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

Pharmaceutical Raw material Flumethasone CAS 2135-17-3

Cas:2135-17-3

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

1.High quality : the purity is 99% min . through multiple producing procedures. 2.Competitive price : low price because of our skilled production technolpgy ,save the production cost at most , and give big profit room to our customers

Flumethasone 2135-17-3

Cas:2135-17-3

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Hangzhou Think Chemical Co. Ltd

Flumethasone CAS No.:2135-17-3 Name: Flumethasone Synonyms: 6a,9a-Difluoro-16a-methyl-11b,17a,21-trihydroxy-1,4-pregnadiene-3,20-dione; 6a,9a-Difluoro-16a-methylprednisolone; 6alpha-Fluorodexamethasone Mo

High purity Flumethasone CAS No.:2135-17-3

Cas:2135-17-3

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Other

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Flumetasone

Cas:2135-17-3

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% Flumethasone 2135-17-3 GMP Manufacturer

Cas:2135-17-3

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

flumethasone

Cas:2135-17-3

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hubei DiBo chemical co., LTD

Name:Flumethasone The alias:6-alpha,9-alpha-difluoro-11-beta,17-alpha,21-tChemicalbookrihydroxy-16-alpha-methylpregna-1,4-diene-3,20-dione; CAS NO:2135-17-3 EINECS NO:218-370-9 Molecular formula:C22H28F2O5 Molecular weight:410.451526 Produc

Flumethasone/CAS:2135-17-3/High quality

Cas:2135-17-3

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

top Flumethasone

Cas:2135-17-3

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

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LIDE PHARMACEUTICALS LIMITED

LIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc. We are specialized in chemical synthesis, process development of pharmaceu

Flumethasone

Cas:2135-17-3

Min.Order:1 Kilogram

FOB Price: $0.9 / 1.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

Flumethasone

Cas:2135-17-3

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Best CAS 2135-17-3 with high quality products

Cas:2135-17-3

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Product Name: flumethasone Other Name RS-2177, NSC-54702 CAS: 2135-17-3 MF: C22H28

Flumethasone

Cas:2135-17-3

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White to white crystalline powder Storage:Store in sealed c

USP Factory Bulk Supply Corticosteroid Flumethasones CAS 2135-17-3

Cas:2135-17-3

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Appearance:White powder Storage:2-8°C Package:25kg/drum Application:Flumethasone is an anti-inflammatory glucocorticoid used in veterinary practice and used as an anti-inflammatory for a variety of animals. It is commonly investigated for its effec

Flumethasone factory price

Cas:2135-17-3

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Flumethasone 2135-17-3

Cas:2135-17-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

HANWAYS CHEMPHARM CO.,LIMITED

Wuhan hanweishi Pharmchem Co., Ltd(Hanways chempharm) is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The leading products range are APIs, Hormones, Peptides

Flumethasone CAS 2135-17-3

Cas:2135-17-3

Min.Order:100 Kilogram

FOB Price: $1.0 / 5.0

Type:Trading Company

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

Flumethasone Endocrine and hormone

Cas:2135-17-3

Min.Order:1 Kilogram

FOB Price: $50.0 / 60.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Flumethasone CAS: 2135-17-3 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediate

Flumethasone CAS: 2135-17-3

Cas:2135-17-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Flumethasone

Cas:2135-17-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Wonda Pharm Limited

1.high quality: quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed. 2.reasonable price: we provide high quality products wi

Pharmaceutical Raw material Flumethasone

Cas:2135-17-3

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Mojin Biotechnology Co.,Ltd

Product quality: Our company have high quality product , and also the product we have good manufacture . First of all, this product is of fine quality. Every finish should be checked by quality inspection system.And every one should be also tried

Flumethasone cas 2135-17-3

Cas:2135-17-3

Min.Order:1 Kilogram

FOB Price: $20.0 / 30.0

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Flumethasone

Cas:2135-17-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Appearance:White crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:Common products:Se

flumethasone

Cas:2135-17-3

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

Flumethasone

Cas:2135-17-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

C24H30F2O5

C24H30F2O5

flumetasone
2135-17-3

flumetasone

Conditions
ConditionsYield
With monoperoxyphthalic acid In dichloromethane; ethyl acetate at 27℃;93%
flumethasone pivalate
2002-29-1

flumethasone pivalate

flumetasone
2135-17-3

flumetasone

Conditions
ConditionsYield
With Curvularia lunata In water at 30℃; for 72h; Yield given;
4,6 alpha,9 alpha-trifluoro-11 beta,17 alpha-dihydroxy-16 alpha-methyl-3-oxoandrosta-1,4-diene

4,6 alpha,9 alpha-trifluoro-11 beta,17 alpha-dihydroxy-16 alpha-methyl-3-oxoandrosta-1,4-diene

A

4,6 alpha,9 alpha-trifluoro-11 beta-hydroxy-16 alpha-methyl-3-oxo-17 alpha-propionyloxyandrosta-1,4-diene

4,6 alpha,9 alpha-trifluoro-11 beta-hydroxy-16 alpha-methyl-3-oxo-17 alpha-propionyloxyandrosta-1,4-diene

B

flumetasone
2135-17-3

flumetasone

Conditions
ConditionsYield
With pyridine In propionic acid anhydride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: potassium carbonate; water / methanol / 10 h
2: hydrogen fluoride / 5 h / -15 - -10 °C
View Scheme
epoxyparamethasone

epoxyparamethasone

flumetasone
2135-17-3

flumetasone

Conditions
ConditionsYield
With hydrogen fluoride at -15 - -10℃; for 5h;
flumetasone
2135-17-3

flumetasone

6α,9α-difluoro-11β,17α-dihydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17β-carboxylic acid
28416-82-2

6α,9α-difluoro-11β,17α-dihydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17β-carboxylic acid

Conditions
ConditionsYield
With water; periodic acid In tetrahydrofuran at 20℃; for 1h;100%
With periodic acid In tetrahydrofuran; water at 0 - 20℃; for 2h;99.12%
With periodic acid In tetrahydrofuran; water at 0 - 20℃; for 5.75h;98%
2-(triphenylmethylthio)ethanoic acid
34914-36-8

2-(triphenylmethylthio)ethanoic acid

flumetasone
2135-17-3

flumetasone

flumethasone 2-(tritylmercapto)acetate

flumethasone 2-(tritylmercapto)acetate

Conditions
ConditionsYield
With dmap In dichloromethane at 20℃;98%
flumetasone
2135-17-3

flumetasone

C22H27BrF2O4

C22H27BrF2O4

Conditions
ConditionsYield
With pyridine; N-Bromosuccinimide; sulfur dioxide at 20℃; for 1h;97.3%
flumetasone
2135-17-3

flumetasone

6α,9-difluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione
2607-06-9

6α,9-difluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione

Conditions
ConditionsYield
With trimethylsilyl iodide In acetonitrile at -20℃; for 2h; Inert atmosphere;93%
flumetasone
2135-17-3

flumetasone

Triethyl orthopropionate
115-80-0

Triethyl orthopropionate

6α,9α-difluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione cyclic 17,21-(ethyl orthopropionate)
22593-09-5

6α,9α-difluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione cyclic 17,21-(ethyl orthopropionate)

Conditions
ConditionsYield
With toluene-4-sulfonic acid In N,N-dimethyl-formamide; toluene at 20℃; for 2h;90%
flumetasone
2135-17-3

flumetasone

6α,9α-difluoro-11β-hydroxy-16α-methylandrosta-1,4-diene-3,17-dione
25256-97-7

6α,9α-difluoro-11β-hydroxy-16α-methylandrosta-1,4-diene-3,17-dione

Conditions
ConditionsYield
In acetonitrile for 1h; Irradiation;50 % Turnov.
flumetasone
2135-17-3

flumetasone

A

6α,9α-difluoro-11β-hydroxy-16α-methylandrosta-1,4-diene-3,17-dione
25256-97-7

6α,9α-difluoro-11β-hydroxy-16α-methylandrosta-1,4-diene-3,17-dione

B

6α,9α-difluoro-11β,17α,21-trihydroxy-16α-methyl-1,5-cyclopregna-3-ene-2,20-dione
389119-99-7

6α,9α-difluoro-11β,17α,21-trihydroxy-16α-methyl-1,5-cyclopregna-3-ene-2,20-dione

Conditions
ConditionsYield
In acetonitrile Quantum yield; Further Variations:; irradiation wavelength; UV-irradiation;
In acetonitrile Quantum yield; Further Variations:; irradiation wavelength; Irradiation;
flumetasone
2135-17-3

flumetasone

6α,9α-difluoro-11β,17α,21-trihydroxy-16α-methyl-1,5-cyclopregna-3-ene-2,20-dione
389119-99-7

6α,9α-difluoro-11β,17α,21-trihydroxy-16α-methyl-1,5-cyclopregna-3-ene-2,20-dione

Conditions
ConditionsYield
In acetonitrile for 2.5h; Irradiation;60 % Turnov.
flumetasone
2135-17-3

flumetasone

6α,9α-difluoro-11β,21-dihydroxy-16α-methyl-17α-propionyloxypregna-1,4-diene-3,20-dione
22593-10-8

6α,9α-difluoro-11β,21-dihydroxy-16α-methyl-17α-propionyloxypregna-1,4-diene-3,20-dione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 90 percent / TsOH / dimethylformamide; toluene / 2 h / 20 °C
2: 96 percent / aq. AcOH / methanol / 0.5 h / Heating
View Scheme
flumetasone
2135-17-3

flumetasone

6α,9α-difluoro-11β,21-dihydroxy-16α-methyl-17α-propionyloxypregn-4-ene-3,20-dione
193408-56-9

6α,9α-difluoro-11β,21-dihydroxy-16α-methyl-17α-propionyloxypregn-4-ene-3,20-dione

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 90 percent / TsOH / dimethylformamide; toluene / 2 h / 20 °C
2: 96 percent / aq. AcOH / methanol / 0.5 h / Heating
3: 85 percent / H2 / (Ph3P)3RhCl / ethanol / 60 h / 760.05 Torr
View Scheme
flumetasone
2135-17-3

flumetasone

6α,9α-difluoro-11β-hydroxy-21-methylsulfonyloxy-16α-methyl-17α-propionyloxypregna-1,4-diene-3,20-dione
64272-25-9

6α,9α-difluoro-11β-hydroxy-21-methylsulfonyloxy-16α-methyl-17α-propionyloxypregna-1,4-diene-3,20-dione

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 90 percent / TsOH / dimethylformamide; toluene / 2 h / 20 °C
2: 96 percent / aq. AcOH / methanol / 0.5 h / Heating
3: 100 percent / pyridine / 2 h
View Scheme
flumetasone
2135-17-3

flumetasone

6α,9α-difluoro-11β-hydroxy-21-methylsulfonyloxy-16α-methyl-17α-propionyloxypregn-4-ene-3,20-dione
193408-57-0

6α,9α-difluoro-11β-hydroxy-21-methylsulfonyloxy-16α-methyl-17α-propionyloxypregn-4-ene-3,20-dione

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 90 percent / TsOH / dimethylformamide; toluene / 2 h / 20 °C
2: 96 percent / aq. AcOH / methanol / 0.5 h / Heating
3: 85 percent / H2 / (Ph3P)3RhCl / ethanol / 60 h / 760.05 Torr
4: 100 percent / pyridine / 2 h
View Scheme
flumetasone
2135-17-3

flumetasone

6α,9α-difluoro-11β-hydroxy-16α-methyl-21-(2-oxotetrahydrofuran-3-ylsulfanyl)-17α-propionyloxypregna-1,4-diene-3,20-dione

6α,9α-difluoro-11β-hydroxy-16α-methyl-21-(2-oxotetrahydrofuran-3-ylsulfanyl)-17α-propionyloxypregna-1,4-diene-3,20-dione

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 90 percent / TsOH / dimethylformamide; toluene / 2 h / 20 °C
2.1: 96 percent / aq. AcOH / methanol / 0.5 h / Heating
3.1: 100 percent / pyridine / 2 h
4.1: NaH / tetrahydrofuran / 0.5 h / 0 °C
4.2: 17 percent / tetrahydrofuran / 22 h / 0 - 21 °C
View Scheme
flumetasone
2135-17-3

flumetasone

6α,9α-difluoro-11β-hydroxy-16α-methyl-21-(2-oxotetrahydrofuran-3-ylsulfanyl)-17α-propionyloxypregn-4-ene-3,20-dione

6α,9α-difluoro-11β-hydroxy-16α-methyl-21-(2-oxotetrahydrofuran-3-ylsulfanyl)-17α-propionyloxypregn-4-ene-3,20-dione

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: 90 percent / TsOH / dimethylformamide; toluene / 2 h / 20 °C
2.1: 96 percent / aq. AcOH / methanol / 0.5 h / Heating
3.1: 85 percent / H2 / (Ph3P)3RhCl / ethanol / 60 h / 760.05 Torr
4.1: 100 percent / pyridine / 2 h
5.1: NaH / tetrahydrofuran / 0.5 h / 0 °C
5.2: 43 percent / tetrahydrofuran / 22 h / 0 - 21 °C
View Scheme
trimethyl ortho-4-bromobutanoate
55444-67-2

trimethyl ortho-4-bromobutanoate

flumetasone
2135-17-3

flumetasone

C27H35BrF2O6
1207376-56-4

C27H35BrF2O6

Conditions
ConditionsYield
toluene-4-sulfonic acid In N,N-dimethyl-formamide at 20℃; for 72h;
methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

flumetasone
2135-17-3

flumetasone

2-[(1R,2S,8S,10S,11S,13R,14R,15S,17S)-1,8-difluoro-14,17-dihydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.02'7.011,15]heptadeca-3,6-dien-14-yl]-2-oxoethyl methanesulfonate
2414-34-8

2-[(1R,2S,8S,10S,11S,13R,14R,15S,17S)-1,8-difluoro-14,17-dihydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.02'7.011,15]heptadeca-3,6-dien-14-yl]-2-oxoethyl methanesulfonate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃;
With pyridine at 0℃; for 2h;
flumetasone
2135-17-3

flumetasone

C29H31F2NO4S2
1345277-64-6

C29H31F2NO4S2

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C
2: potassium carbonate / acetone / Reflux
View Scheme
flumetasone
2135-17-3

flumetasone

C61H101F2N3O16

C61H101F2N3O16

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: periodic acid / 1,4-dioxane; water / 2 h / 20 °C
2: triethylamine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 18 h / 0 - 20 °C / Inert atmosphere
View Scheme
flumetasone
2135-17-3

flumetasone

C53H87F2N3O13
442638-54-2

C53H87F2N3O13

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: periodic acid / 1,4-dioxane; water / 2 h / 20 °C
2: triethylamine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 18 h / 0 - 20 °C / Inert atmosphere
View Scheme
C12H24N4O2
1281702-63-3

C12H24N4O2

flumetasone
2135-17-3

flumetasone

A

C34H50F2N4O6

C34H50F2N4O6

B

C46H72F2N8O7

C46H72F2N8O7

Conditions
ConditionsYield
With acetic acid In ethanol; water at 70℃; for 0.5h;
flumetasone
2135-17-3

flumetasone

6α,9α-difluoro-11β-hydroxy-16α-methyl-3-oxo-17α-(propionyloxy)androsta-1,4-diene-17β-carboxylic acid
65429-42-7

6α,9α-difluoro-11β-hydroxy-16α-methyl-3-oxo-17α-(propionyloxy)androsta-1,4-diene-17β-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: sodium periodate / water; tetrahydrofuran / 2 h / 25 - 30 °C
2.1: triethylamine / acetone / 3 h / 0 - 5 °C
2.2: 2.5 h / 40 - 45 °C
View Scheme
Multi-step reaction with 2 steps
1.1: periodic acid / water; tetrahydrofuran / 2 h / 0 - 10 °C
2.1: triethylamine / acetone / 1 h / 0 - 10 °C
2.2: 2 h
View Scheme
flumetasone
2135-17-3

flumetasone

17β-[(N,N-dimethylcarbamoyl)thio]formyl-6α,9α-difluoro-11β-hydroxy-16α-methyl-17α-propionyloxy-3-one androstone-1,4-diene
105638-31-1

17β-[(N,N-dimethylcarbamoyl)thio]formyl-6α,9α-difluoro-11β-hydroxy-16α-methyl-17α-propionyloxy-3-one androstone-1,4-diene

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: sodium periodate / water; tetrahydrofuran / 2 h / 25 - 30 °C
2.1: triethylamine / acetone / 3 h / 0 - 5 °C
2.2: 2.5 h / 40 - 45 °C
3.1: sodium iodide; triethylamine / tetrahydrofuran / 4 h / 70 - 75 °C
View Scheme
Multi-step reaction with 3 steps
1.1: periodic acid / water; tetrahydrofuran / 2 h / 0 - 10 °C
2.1: triethylamine / acetone / 1 h / 0 - 10 °C
2.2: 2 h
3.1: sodium iodide; triethylamine / tetrahydrofuran / 16 h / 20 °C
View Scheme
flumetasone
2135-17-3

flumetasone

17-propionate carbothioic acid
80474-45-9

17-propionate carbothioic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: sodium periodate / water; tetrahydrofuran / 2 h / 25 - 30 °C
2.1: triethylamine / acetone / 3 h / 0 - 5 °C
2.2: 2.5 h / 40 - 45 °C
3.1: sodium iodide; triethylamine / tetrahydrofuran / 4 h / 70 - 75 °C
4.1: morpholine / 3 h / 20 °C
View Scheme
Multi-step reaction with 4 steps
1.1: periodic acid / water; tetrahydrofuran / 2 h / 0 - 10 °C
2.1: triethylamine / acetone / 1 h / 0 - 10 °C
2.2: 2 h
3.1: sodium iodide; triethylamine / tetrahydrofuran / 16 h / 20 °C
4.1: calcium hydroxide / methanol / 24 h / 25 - 30 °C
View Scheme
flumetasone
2135-17-3

flumetasone

flixotide
80474-14-2

flixotide

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: sodium periodate / water; tetrahydrofuran / 2 h / 25 - 30 °C
2.1: triethylamine / acetone / 3 h / 0 - 5 °C
2.2: 2.5 h / 40 - 45 °C
3.1: sodium iodide; triethylamine / tetrahydrofuran / 4 h / 70 - 75 °C
4.1: morpholine / 3 h / 20 °C
5.1: potassium carbonate / acetone / 0.5 h / 20 °C
5.2: 0 - 5 °C
View Scheme

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