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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 4-Methylamino-3-Nitrobenzoic Acid supplier in China

Cas:41263-74-5

Min.Order:1 Metric Ton

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Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 4-(Methylamino)-3-nitrobenzoic acid

Cas:41263-74-5

Min.Order:1

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Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% 41263-74-5 4-(METHYLAMINO)-3-NITROBENZOIC ACID Manufacturer

Cas:41263-74-5

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

4-Aminomethyl-3-Nitrobenzoic Acid

Cas:41263-74-5

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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ANQING CHICO PHARMACEUTICAL CO.,LTD.

High quality. Factory supply. In stock. Best price.1.Quick response within 24 hours;2.Best quality in your requirement;?3.We pay more attention on delivery time, and usually ship on time;4.Under the premise of safety and effectiveness, we can produce

4-Methylamino-3-nitrobenzoic acid

Cas:41263-74-5

Min.Order:0

Negotiable

Type:Trading Company

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

4-Methylamino-3-nitrobenzoic acid Manufacturer/High quality/Best price/In stock

Cas:41263-74-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

4-(Methylamino)-3-nitrobenzoic acid

Cas:41263-74-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Product Name: 4-(METHYLAMINO)-3-NITROBENZOIC ACID Synonyms: 4-(METHYLAMINO)-3-NITROBENZOIC ACID;NSC 138300;4-(MethylaMino)-3-nitrobenzoic acid 98%;Benzoic acid, 4-(MethylaMino)-3-nitro-;Dabigatran Etexilate Intermediate 5 CAS: 41263-74-5

41263-74-5 4-(METHYLAMINO)-3-NITROBENZOIC ACID

Cas:41263-74-5

Min.Order:1 Gram

FOB Price: $8900.0

Type:Lab/Research institutions

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LIDE PHARMACEUTICALS LIMITED

LIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.

4-(METHYLAMINO)-3-NITROBENZOIC ACID

Cas:41263-74-5

Min.Order:1 Kilogram

FOB Price: $0.9 / 1.0

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 41263-74-5 with competitive price

Cas:41263-74-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Name: 4-Methylamino-3-nitrobenzoic acid Synonyms: 4-Aminomethyl-3-nitrobenzoic acid CAS:41263-74-5 MF: C8H7N2O4 Appearance: white powder Storage:Store in cool and dry place, away from sun light. Package: 25kgs/drum Application:Organic synthesis Tr

4-Methylamino-3-nitrobenzoic acid

Cas:41263-74-5

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

4-(METHYLAMINO)-3-NITROBENZOIC ACID 41263-74-5

Cas:41263-74-5

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

4-Methylamino-3-nitrobenzoic acid 41263-74-5

Cas:41263-74-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

4-(METHYLAMINO)-3-NITROBENZOIC ACID CAS:41263-74-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quali

4-(METHYLAMINO)-3-NITROBENZOIC ACID CAS:41263-74-5

Cas:41263-74-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

4-Methylamino-3-nitrobenzoic acid

Cas:41263-74-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:41263-74-5

Cas:41263-74-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hebei Mojin Biotechnology Co.,Ltd

Hebei Mojin Biotechnology Co., Ltd, Our company is a professional chemical raw materials and chemical reagents research and development production enterprises. We have several production line,So we can control the lowest price. We also have several

4-(Methylamino)-3-nitrobenzoic acid cas:41263-74-5

Cas:41263-74-5

Min.Order:25 Gram

FOB Price: $90.0 / 100.0

Type:Trading Company

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Wuhan Zenuo Biological Medicine Technology Co Ltd

Product Name: 4-(METHYLAMINO)-3-NITROBENZOIC ACID Synonyms: 4-(METHYLAMINO)-3-NITROBENZOIC ACID;NSC 138300;4-(MethylaMino)-3-nitrobenzoic acid 98%;Benzoic acid, 4-(MethylaMino)-3-nitro-;Dabigatran Etexilate Intermediate 5 CAS: 41263-74-5 MF:

4-(METHYLAMINO)-3-NITROBENZOIC ACID Manufactory best quality

Cas:41263-74-5

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

4-Methylamino-3-Nitrobenzoic Acid

Cas:41263-74-5

Min.Order:0

Negotiable

Type:Manufacturers

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Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

4-Methylamino-3-nitrobenzoic acid

Cas:41263-74-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

CAS41263-74-5 4-(METHYLAMINO)-3-NITROBENZOIC ACID

Cas:41263-74-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

4-Methylamino-3-nitrobenzoic acid

Cas:41263-74-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

4-Methylamino-3-nitrobenzoic acid/Manufacturer/High quality/Best price

Cas:41263-74-5

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 4-Methylamino-3-Nitrobenzoic Acid

Cas:41263-74-5

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:10g/bag,or as your request Application:For medicine , pesticide intermediates Tran

4-Methylamino-3-nitrobenzoic acid

Cas:41263-74-5

Min.Order:1 Gram

Negotiable

Type:Trading Company

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Jinan Finer Chemical Co., Ltd

Name: 4-Methylamino-3-nitrobenzoic acid Cas: 41263-74-5 Appearance: light-yellow to white powder Capacity:10MT/year Application: Dabigatran intermediate Assay: min99% Standard: enterprise Brand: Finerchem Molecular Formula C8H8

4-Methylamino-3-nitrobenzoic acid

Cas:41263-74-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

4-(METHYLAMINO)-3-NITROBENZOIC ACID

Cas:41263-74-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Best Offer4-(METHYLAMINO)-3-NITROBENZOIC ACID

Cas:41263-74-5

Min.Order:0

Negotiable

Type:Trading Company

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Shanghai Minstar Chemical Co., Ltd

4-(METHYLAMINO)-3-NITROBENZOIC ACID Chemical Properties Melting point >300°C Boiling point 393.7±37.0 °C(Predicted) density 1.472±0.06 g/cm3(Predicted) storage temp. Keep in dark place,Sealed in dry,Room Tempe

4-(METHYLAMINO)-3-NITROBENZOIC ACID

Cas:41263-74-5

Min.Order:1 Gram

FOB Price: $66.0

Type:Lab/Research institutions

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Hangzhou Think Chemical Co. Ltd

HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the marketing & distribution, thinkchem specializes in exp

4-Methylamino-3-nitrobenzoic acid

Cas:41263-74-5

Min.Order:0

Negotiable

Type:Other

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Synthetic route

methylamine
74-89-5

methylamine

4-chloro-3-nitrobenzoate
96-99-1

4-chloro-3-nitrobenzoate

4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

Conditions
ConditionsYield
In water at 100℃; for 14h;100%
In water at 80℃; for 5h;100%
Stage #1: methylamine; 4-chloro-3-nitrobenzoate In water for 4h; Reflux;
Stage #2: With sulfuric acid In water at 20℃; pH=2; Product distribution / selectivity;
95.5%
3-fluoro-4-nitrobenzoic acid
403-21-4

3-fluoro-4-nitrobenzoic acid

methylamine
74-89-5

methylamine

4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

Conditions
ConditionsYield
Stage #1: 3-fluoro-4-nitrobenzoic acid; methylamine In DMF (N,N-dimethyl-formamide); water at 20℃; for 1h;
Stage #2: With potassium hydrogensulfate In water pH=2;
100%
3-nitro-4-fluorobenzoic acid
453-71-4

3-nitro-4-fluorobenzoic acid

methylamine
74-89-5

methylamine

4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

Conditions
ConditionsYield
In methanol; ethanol at 20℃; for 2h;99%
In methanol at 20℃; for 18h;99%
In methanol at 20℃; for 10h;98%
4-bromo-3-nitrobenzoic acid
6319-40-0

4-bromo-3-nitrobenzoic acid

methylamine
74-89-5

methylamine

4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

Conditions
ConditionsYield
With D-myo-inositol; copper; caesium carbonate In water at 100℃;92%
4-chloro-3-nitrobenzoate
96-99-1

4-chloro-3-nitrobenzoate

4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

Conditions
ConditionsYield
With methylamine In water86%
4-methylamino-3-nitro-benzoic acid methyl ester
36242-50-9

4-methylamino-3-nitro-benzoic acid methyl ester

4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

Conditions
ConditionsYield
Stage #1: 4-methylamino-3-nitro-benzoic acid methyl ester With lithium hydroxide In tetrahydrofuran; water at 20℃; for 16h;
Stage #2: With hydrogenchloride In tetrahydrofuran; water pH=Ca. 5;
84%
With lithium hydroxide In tetrahydrofuran; water at 20℃; for 16h;84%
With water; lithium hydroxide In tetrahydrofuran at 20℃; for 16h;84%
3,4-dinitrobenzoic acid
528-45-0

3,4-dinitrobenzoic acid

methylamine
74-89-5

methylamine

4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

Conditions
ConditionsYield
Stage #1: 3,4-dinitrobenzoic acid; methylamine With triethylamine In methanol; ethanol at 20℃; for 24h;
Stage #2: With acetic acid In water
81%
nitro acetate
591-09-3

nitro acetate

4-(N,N-dimethylamino)-3-nitrobenzoic acid
28096-56-2

4-(N,N-dimethylamino)-3-nitrobenzoic acid

4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

ethyl 4-(methylamino)-3-nitrobenzoate
71254-71-2

ethyl 4-(methylamino)-3-nitrobenzoate

4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

Conditions
ConditionsYield
With potassium hydroxide
4-(N,N-dimethylamino)-3-nitrobenzoic acid
28096-56-2

4-(N,N-dimethylamino)-3-nitrobenzoic acid

4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

Conditions
ConditionsYield
With potassium permanganate; sodium carbonate
With nitrosyl acetate
4-dimethylamino-3-nitrobenzaldehyde
59935-39-6

4-dimethylamino-3-nitrobenzaldehyde

4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

Conditions
ConditionsYield
With potassium permanganate; sodium carbonate
Multi-step reaction with 4 steps
1: alkali; hydroxylamine hydrochloride
2: acetic acid anhydride; sodium acetate
3: NaOH-solution; alcohol
4: potassium permanganate; natrium carbonate
View Scheme
sulfuric acid
7664-93-9

sulfuric acid

4-(methoxycarbonyl)-2-nitro-N,N-dimethylaniline
82080-46-4

4-(methoxycarbonyl)-2-nitro-N,N-dimethylaniline

nitric acid
7697-37-2

nitric acid

A

4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

B

3.5-dinitro-4-methylnitramino-benzoic acid methyl ester

3.5-dinitro-4-methylnitramino-benzoic acid methyl ester

Conditions
ConditionsYield
at 70 - 75℃;
4-(dimethylamino)-3-nitrobenzonitrile
19005-63-1

4-(dimethylamino)-3-nitrobenzonitrile

4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NaOH-solution; alcohol
2: potassium permanganate; natrium carbonate
View Scheme
4-dimethylamino-3-nitro-benzaldehyde-oxime

4-dimethylamino-3-nitro-benzaldehyde-oxime

4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: acetic acid anhydride; sodium acetate
2: NaOH-solution; alcohol
3: potassium permanganate; natrium carbonate
View Scheme
p-N,N-dimethylaminobenzoic acid
619-84-1

p-N,N-dimethylaminobenzoic acid

4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: HNO3+H2SO4 / 0 °C
2: potassium permanganate; natrium carbonate
View Scheme
ethyl 4-ethoxy-3-nitrobenzoate
937625-32-6

ethyl 4-ethoxy-3-nitrobenzoate

4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: alcohol / 130 - 140 °C / im Druckrohr
2: KOH-solution
View Scheme
methyl 3-nitro-4-chlorobenzoate
14719-83-6

methyl 3-nitro-4-chlorobenzoate

4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: N,N-dimethyl-formamide / 70 - 90 °C / Inert atmosphere
2.1: lithium hydroxide / tetrahydrofuran; water / 16 h / 20 °C
2.2: pH Ca. 5
View Scheme
Multi-step reaction with 2 steps
1: tetrahydrofuran; N,N-dimethyl-formamide / 20 - 90 °C / Inert atmosphere
2: lithium hydroxide / tetrahydrofuran; water / 16 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: N,N-dimethyl-formamide; tetrahydrofuran / 70 - 90 °C
2: lithium hydroxide; water / tetrahydrofuran / 16 h / 20 °C
View Scheme
4-Fluorobenzoic acid
456-22-4

4-Fluorobenzoic acid

4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sulfuric acid; nitric acid / 10 h / 20 °C
2: methanol / 10 h / 20 °C
View Scheme
4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

4-methylamino-3-nitro-benzoic acid chloride
82357-48-0

4-methylamino-3-nitro-benzoic acid chloride

Conditions
ConditionsYield
With thionyl chloride Chlorination; Heating;100%
With thionyl chloride; N,N-dimethyl-formamide In dichloromethane Reflux;100%
With thionyl chloride; N,N-dimethyl-formamide In dichloromethane at 30℃;100%
(R)-piperidin-3-ylcarbamic acid tert-butyl ester
309956-78-3

(R)-piperidin-3-ylcarbamic acid tert-butyl ester

4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

1,1-dimethylethyl ((3R)-1-{[4-(methylamino)-3-nitrophenyl]carbonyl}-3-piperidinyl)carbamate
1549812-10-3

1,1-dimethylethyl ((3R)-1-{[4-(methylamino)-3-nitrophenyl]carbonyl}-3-piperidinyl)carbamate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 16h;100%
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 16h;100%
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 16h;100%
4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

3-amino-4-(methylamino)benzoic acid
66315-15-9

3-amino-4-(methylamino)benzoic acid

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In methanol at 20℃; for 2h;99%
With palladium 10% on activated carbon; hydrogen In methanol at 20℃;99%
With palladium on activated charcoal; hydrogen In methanol at 20℃; for 48h;36.5%
2-chloromethyl-1-methyl-1H-benzimidazole-5 ethyl acetate
103041-38-9

2-chloromethyl-1-methyl-1H-benzimidazole-5 ethyl acetate

4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

ethyl 3-[[4-(methylamino)-3-nitrobenzoyl](pyridin-2-yl)amino]propanoate hydrochloride
1187067-68-0

ethyl 3-[[4-(methylamino)-3-nitrobenzoyl](pyridin-2-yl)amino]propanoate hydrochloride

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 18h; Solvent; Reagent/catalyst;95.2%
4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

C8H7ClN2O4

C8H7ClN2O4

Conditions
ConditionsYield
With thionyl chloride In N,N-dimethyl-formamide; toluene at 0 - 70℃;82%
methanol
67-56-1

methanol

4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

4-methylamino-3-nitro-benzoic acid methyl ester
36242-50-9

4-methylamino-3-nitro-benzoic acid methyl ester

Conditions
ConditionsYield
With sulfuric acid for 6h; Reflux;77%
Stage #1: methanol; 4-(methylamino)-3-nitrobenzoic acid With hydrogenchloride In N,N-dimethyl-formamide for 10h; Reflux;
Stage #2: With sodium hydrogencarbonate In water
32%
4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

4-bromo-aniline
106-40-1

4-bromo-aniline

N-(4-bromo-phenyl)-4-methylamino-3-nitro-benzamide
1003098-13-2

N-(4-bromo-phenyl)-4-methylamino-3-nitro-benzamide

Conditions
ConditionsYield
Stage #1: 4-(methylamino)-3-nitrobenzoic acid With pyridine; 1-chloro-1-(dimethylamino)-2-methyl-1-propene In dichloromethane
Stage #2: 4-bromo-aniline In dichloromethane for 16h;
68%
ethanol
64-17-5

ethanol

4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

3-amino-4-(methylamino)benzoic acid
66315-15-9

3-amino-4-(methylamino)benzoic acid

Conditions
ConditionsYield
palladium-carbon61%
2-chloromethyl-1-methyl-1H-benzimidazole-5 ethyl acetate
103041-38-9

2-chloromethyl-1-methyl-1H-benzimidazole-5 ethyl acetate

4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

ethyl 3-{[{1-(methylamino)-2-nitrophen-4-yl}carbonyl](pyridyn-2-yl)amino}propanoate hydrochloride

ethyl 3-{[{1-(methylamino)-2-nitrophen-4-yl}carbonyl](pyridyn-2-yl)amino}propanoate hydrochloride

Conditions
ConditionsYield
Stage #1: 4-(methylamino)-3-nitrobenzoic acid With thionyl chloride In N,N-dimethyl-formamide for 0.75h; Reflux;
Stage #2: 2-chloromethyl-1-methyl-1H-benzimidazole-5 ethyl acetate With triethylamine In tetrahydrofuran at 20 - 60℃;
Stage #3: With hydrogenchloride In water; ethyl acetate Product distribution / selectivity;
47.2%
2-chloromethyl-1-methyl-1H-benzimidazole-5 ethyl acetate
103041-38-9

2-chloromethyl-1-methyl-1H-benzimidazole-5 ethyl acetate

4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

ethyl 3-{[{1-(methylamino)-2-nitrophen-4-yl}carbonyl](pyridyn-2-yl)amino}propanoate hydrochloride

ethyl 3-{[{1-(methylamino)-2-nitrophen-4-yl}carbonyl](pyridyn-2-yl)amino}propanoate hydrochloride

Conditions
ConditionsYield
Stage #1: 4-(methylamino)-3-nitrobenzoic acid With thionyl chloride In N,N-dimethyl-formamide for 0.75h; Reflux;
Stage #2: 2-chloromethyl-1-methyl-1H-benzimidazole-5 ethyl acetate With triethylamine In tetrahydrofuran at 20 - 60℃;
Stage #3: With hydrogenchloride In ethyl acetate Product distribution / selectivity;
47.2%
ethanol
64-17-5

ethanol

4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

ethyl 4-(methylamino)-3-nitrobenzoate
71254-71-2

ethyl 4-(methylamino)-3-nitrobenzoate

Conditions
ConditionsYield
With sulfuric acid
4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

acetic anhydride
108-24-7

acetic anhydride

4-(acetyl-methyl-amino)-3-nitro-benzoic acid

4-(acetyl-methyl-amino)-3-nitro-benzoic acid

Conditions
ConditionsYield
With sulfuric acid
4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

1-methyl-2-(4-phenoxy-phenyl)-1H-benzoimidazole-5-carboxylic acid amide

1-methyl-2-(4-phenoxy-phenyl)-1H-benzoimidazole-5-carboxylic acid amide

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: SOCl2
2: NH3
3: H2 / Pd/C / ethanol
4: 65 percent / Na2S2O5 / dimethylformamide / 100 °C
View Scheme
4-(methylamino)-3-nitrobenzoic acid
41263-74-5

4-(methylamino)-3-nitrobenzoic acid

3-amino-4-(methylamino)benzamide
39033-67-5

3-amino-4-(methylamino)benzamide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: SOCl2
2: NH3
3: H2 / Pd/C / ethanol
View Scheme
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