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Hebei Kunsui Technology Co., Ltd.

1. A strong scientific research team . 2. Stable quality (with a complete scientific research center and testing center to ensure the quality stability of each batch of products). 3. Rich export experience (with practical experience in exporting to m

Pharmaceutical Intermediate Iminodibenzyl Powder CAS 494-19-9

Cas:494-19-9

Min.Order:1 Kilogram

FOB Price: $8.2 / 8.8

Type:Trading Company

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Iminodibenzyl Manufacturer/High quality/Best price/In stock

Cas:494-19-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Iminodibenzyl supplier in China

Cas:494-19-9

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

Hebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car

Factory supply Iminodibenzyl

Cas:494-19-9

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 10,11-dihydro-5H-dibenz[b,f]azepine

Cas:494-19-9

Min.Order:1

Negotiable

Type:Other

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi

Iminodibenzyl

Cas:494-19-9

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Iminodibenzyl CAS 494-19-9 10,11-Dihydro-5H-dibenz[b,f]azepine CAS no 494-19-9 5H-Dibenz (b,f)azepine, 10,11-dihydro- Iminodibenzyl 10,11-Dihydro-5H-dibenz[b,f]azepine 5H-Dibenz (b,f)azepine, 10,11-dihydro- Iminodibenzyl CAS 494-19-9 10,1

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

494-19-9 Iminodibenzyl

Cas:494-19-9

Min.Order:1 Kilogram

FOB Price: $1000.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

Iminodibenzyl

Cas:494-19-9

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Hot sale CAS 494-19-9 with fast shipping

Cas:494-19-9

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after the dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available &diam

Iminodibenzyl CAS494-19-9

Cas:494-19-9

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Chemical Name Iminodibenzyl CAS Number 494-19-9 Molecular Formula C14H13N Molecular Weight

Iminodibenzyl CAS: 494-19-9

Cas:494-19-9

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best s

Iminodibenzyl 494-19-9 Antiepileptic Drugs Factory Price

Cas:494-19-9

Min.Order:10 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

5H-Dibenz[b,f]azepine,10,11-dihydro- 494-19-9

Cas:494-19-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

Iminodibenzyl CAS:494-19-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates

Iminodibenzyl CAS:494-19-9

Cas:494-19-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

5H-Dibenz[b,f]azepine,10,11-dihydro-

Cas:494-19-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:494-19-9

Cas:494-19-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

cas 494-19-9 CAS 494-19-9 Iminodibenzyl

Cas:494-19-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

Iminodibenzyl

Cas:494-19-9

Min.Order:1 Kilogram

FOB Price: $15.0 / 25.0

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Iminodibenzyl

Cas:494-19-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

superior quality Appearance:YELLOWISH TO BEIGE CRYSTALLINE POWDER Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:10,11-Dihydro-5H-dibenzo[b,f]aze

Iminodibenzyl

Cas:494-19-9

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Iminodibenzyl

Cas:494-19-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

IMINODIBENZYL

Cas:494-19-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Iminodibenzyl

Cas:494-19-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products Iminodibenzyl

Cas:494-19-9

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and als

Iminodibenzyl

Cas:494-19-9

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Iminodibenzyl

Cas:494-19-9

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

Iminodibenzyl

Cas:494-19-9

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: Iminodibenzyl CAS No.:494-19-9 Molecule Formula:C14H13N Molecule Weight:195.26 Purity: 99.0% Package: 25kg/drum Description:Pale yellow crystalline powder Manufacture Standards:Enterprise Standard TES

High Quality Iminodibenzyl

Cas:494-19-9

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

High Purity Iminodibenzyl

Cas:494-19-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

5-acetyliminodibenzyl
13080-75-6

5-acetyliminodibenzyl

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

Conditions
ConditionsYield
With triethyl borane; sodium hydroxide In tert-butyl methyl ether at 80℃; for 6h; Inert atmosphere; Sealed tube;99%
Stage #1: 5-acetyliminodibenzyl With Triethoxysilane; sodium triethylborohydride In tert-butyl methyl ether at 80℃; for 6h;
Stage #2: With hydrogenchloride In tert-butyl methyl ether; water at 20℃; for 1h; chemoselective reaction;
99%
Multi-step reaction with 2 steps
1: potassium hydroxide; triethyl borane / tetrahydrofuran / 24 h / 25 °C / Inert atmosphere; Schlenk technique; Sealed tube
2: sodium hydroxide; water / tetrahydrofuran / 1 h / 25 °C / Inert atmosphere; Schlenk technique; Sealed tube
View Scheme
5-propionyl-10,11-dihydro-5H-dibenzo[b,f]azepine
40583-89-9

5-propionyl-10,11-dihydro-5H-dibenzo[b,f]azepine

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

Conditions
ConditionsYield
With triethyl borane; sodium hydroxide In tert-butyl methyl ether at 80℃; for 6h; Inert atmosphere; Sealed tube;99%
Stage #1: 5-propionyl-10,11-dihydro-5H-dibenzo[b,f]azepine With Triethoxysilane; sodium triethylborohydride In tert-butyl methyl ether at 80℃; for 6h;
Stage #2: With hydrogenchloride In tert-butyl methyl ether; water at 20℃; for 1h; chemoselective reaction;
81%
Multi-step reaction with 2 steps
1: potassium hydroxide; triethyl borane / tetrahydrofuran / 24 h / 100 °C / Inert atmosphere; Schlenk technique; Sealed tube
2: sodium hydroxide; water / tetrahydrofuran / 1 h / 25 °C / Inert atmosphere; Schlenk technique; Sealed tube
View Scheme
dibenzoazepine
256-96-2

dibenzoazepine

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

Conditions
ConditionsYield
With [Fe3(1,1,1,3,3,3-hexamethyldisilazan-2-ide)4]Fe(η6-toluene); hydrogen at 20℃; under 1425.14 Torr; for 3h; Inert atmosphere; Glovebox; chemoselective reaction;92%
With tetraethylammonium perchlorate; ammonium chloride In water; N,N-dimethyl-formamide cathodic (Hg, -2.0 V vs. SCE) reduction;82%
dibenzoazepine
256-96-2

dibenzoazepine

A

9-methyl-acridine
611-64-3

9-methyl-acridine

B

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

Conditions
ConditionsYield
With iodine; hypophosphorous acid In acetic acid for 24h; Heating;A 92%
B 8%
10,11-dihydro-dibenzo[b,f]azepine-5-carbonyl chloride
33948-19-5

10,11-dihydro-dibenzo[b,f]azepine-5-carbonyl chloride

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

Conditions
ConditionsYield
In acetonitrile electrolysis (Et4NClO4, Hg-dropelectrode);90%
10,11-dihydro-dibenzo[b,f]azepine-5-carboxylic acid prop-2-ynyl ester

10,11-dihydro-dibenzo[b,f]azepine-5-carboxylic acid prop-2-ynyl ester

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

Conditions
ConditionsYield
With benzyltriethylammonium tetrathiomolybdate In acetonitrile at 25℃; for 0.75h; sonicated;88%
C18H19NO

C18H19NO

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

Conditions
ConditionsYield
Stage #1: C18H19NO With Triethoxysilane; sodium triethylborohydride In tert-butyl methyl ether at 80℃; for 6h;
Stage #2: With hydrogenchloride In tert-butyl methyl ether; water at 20℃; for 1h; chemoselective reaction;
87%
With triethyl borane; sodium hydroxide In tert-butyl methyl ether at 80℃; for 6h; Inert atmosphere; Sealed tube;86%
Multi-step reaction with 2 steps
1: potassium hydroxide; triethyl borane / tetrahydrofuran / 24 h / 100 °C / Inert atmosphere; Schlenk technique; Sealed tube
2: sodium hydroxide; water / tetrahydrofuran / 1 h / 25 °C / Inert atmosphere; Schlenk technique; Sealed tube
View Scheme
C14H13Br2N

C14H13Br2N

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

Conditions
ConditionsYield
With C55H46N4O4W; potassium carbonate; N-ethyl-N,N-diisopropylamine In acetonitrile for 12h; Inert atmosphere; Irradiation;68%
C21H25NO

C21H25NO

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

Conditions
ConditionsYield
With triethyl borane; sodium hydroxide In tert-butyl methyl ether at 80℃; for 6h; Inert atmosphere; Sealed tube;67%
Stage #1: C21H25NO With Triethoxysilane; sodium triethylborohydride In tert-butyl methyl ether at 80℃; for 6h;
Stage #2: With hydrogenchloride In tert-butyl methyl ether; water at 20℃; for 1h; chemoselective reaction;
62%
Multi-step reaction with 2 steps
1: potassium hydroxide; triethyl borane / tetrahydrofuran / 24 h / 100 °C / Inert atmosphere; Schlenk technique; Sealed tube
2: sodium hydroxide; water / tetrahydrofuran / 1 h / 25 °C / Inert atmosphere; Schlenk technique; Sealed tube
View Scheme
5-acetyliminodibenzyl
13080-75-6

5-acetyliminodibenzyl

A

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

B

11-ethyliminodibenzyl
40583-88-8

11-ethyliminodibenzyl

C

ethanol
64-17-5

ethanol

Conditions
ConditionsYield
With Mo2((1)-H)2(OtBu)6; diphenylsilane In toluene for 25h; Reagent/catalyst; Solvent; Inert atmosphere; Schlenk technique; Reflux;A 62%
B 36%
C n/a
sodium cyanide
773837-37-9

sodium cyanide

impramine
50-49-7

impramine

A

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

B

2-((3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)-(methyl)amino)acetonitrile

2-((3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)-(methyl)amino)acetonitrile

C

2-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-4-(dimethylamino)butanenitrile

2-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-4-(dimethylamino)butanenitrile

Conditions
ConditionsYield
With [4,4’-bis(1,1-dimethylethyl)-2,2’-bipyridine-N1,N1‘]bis [3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-N]phenyl-C]iridium(III) hexafluorophosphate; acetic acid In acetonitrile at 20℃; for 24h; Irradiation; Sealed tube;A 50%
B 22%
C 23%
dibenzoazepine
256-96-2

dibenzoazepine

acetic acid
64-19-7

acetic acid

A

9-methyl-acridine
611-64-3

9-methyl-acridine

B

5-acetyliminodibenzyl
13080-75-6

5-acetyliminodibenzyl

C

9-methyl-9,10-dihydroacridine
4217-52-1

9-methyl-9,10-dihydroacridine

D

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

Conditions
ConditionsYield
With iodine; hypophosphorous acid for 96h; Heating;A 18%
B 9%
C 20%
D 47%
2-bromophenylacetyl chloride
55116-09-1

2-bromophenylacetyl chloride

aniline
62-53-3

aniline

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

Conditions
ConditionsYield
Stage #1: aniline With copper(l) iodide; n-butyllithium; tetraethylammonium bromide; triethylamine In tetrahydrofuran at -50℃; for 4h; Inert atmosphere;
Stage #2: 2-bromophenylacetyl chloride In tetrahydrofuran at 70℃; for 5h; Inert atmosphere;
45.7%
1-nitro-2-phenethylbenzene
6796-01-6

1-nitro-2-phenethylbenzene

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

Conditions
ConditionsYield
With trifluoroacetic acid; zinc45%
potassium cyanide

potassium cyanide

impramine
50-49-7

impramine

A

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

B

2-((3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)-(methyl)amino)acetonitrile

2-((3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)-(methyl)amino)acetonitrile

C

2-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-4-(dimethylamino)butanenitrile

2-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-4-(dimethylamino)butanenitrile

Conditions
ConditionsYield
With 2-Picolinic acid; iron(III) chloride; tert-Butyl peroxybenzoate; 18-crown-6 ether In acetonitrile at 50℃; for 48h;A 6%
B 35%
C 15%
5-[3-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-4-methylene-4,5-dihydro-isoxazol-5-yl]-10,11-dihydro-5H-dibenzo[b,f]azepine
152700-41-9

5-[3-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-4-methylene-4,5-dihydro-isoxazol-5-yl]-10,11-dihydro-5H-dibenzo[b,f]azepine

A

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

B

4-Chloromethyl-3-(3,5-dichloro-2,4,6-trimethyl-phenyl)-isoxazole

4-Chloromethyl-3-(3,5-dichloro-2,4,6-trimethyl-phenyl)-isoxazole

C

5-[3-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-isoxazol-(4Z)-ylidenemethyl]-10,11-dihydro-5H-dibenzo[b,f]azepine

5-[3-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-isoxazol-(4Z)-ylidenemethyl]-10,11-dihydro-5H-dibenzo[b,f]azepine

D

4-[3-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-isoxazol-4-ylmethyl]-10,11-dihydro-5H-dibenzo[b,f]azepine

4-[3-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-isoxazol-4-ylmethyl]-10,11-dihydro-5H-dibenzo[b,f]azepine

Conditions
ConditionsYield
With zinc(II) chloride In toluene for 6h; Heating; Further byproducts given;A 14%
B 3%
C 33%
D 22%
Imipramine hydrochloride
113-52-0

Imipramine hydrochloride

A

desipramine
50-47-5

desipramine

B

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

C

10-Hydroxyimipramine
796-28-1

10-Hydroxyimipramine

Conditions
ConditionsYield
In water Ambient temperature; M. griseo-cyanus (ATCC 1207a); further microbial agents;A 10 mg
B n/a
C n/a
Imipramine hydrochloride
113-52-0

Imipramine hydrochloride

A

desipramine
50-47-5

desipramine

B

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

C

10-Hydroxyimipramine
796-28-1

10-Hydroxyimipramine

D

2-hydroxyimipramine
303-70-8

2-hydroxyimipramine

Conditions
ConditionsYield
In water for 480h; Ambient temperature; C. blakesleeana (ATCC 8688a); further microbial agents; Further byproducts given;A n/a
B n/a
C 30 mg
D 88 mg
Imipramine hydrochloride
113-52-0

Imipramine hydrochloride

A

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

B

10-Hydroxyimipramine
796-28-1

10-Hydroxyimipramine

C

2-hydroxyimipramine
303-70-8

2-hydroxyimipramine

D

imipramine N-oxide
6829-98-7

imipramine N-oxide

Conditions
ConditionsYield
In water; N,N-dimethyl-formamide for 480h; Ambient temperature; C. blakesleeana (ATCC 8688a); further microbial agents; Further byproducts given;A n/a
B 30 mg
C 88 mg
D n/a
Imipramine hydrochloride
113-52-0

Imipramine hydrochloride

A

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

B

imipramine N-oxide
6829-98-7

imipramine N-oxide

Conditions
ConditionsYield
In water; N,N-dimethyl-formamide for 360h; Ambient temperature; F. oxysporum f. sp. cepae (ATCC 11711); further microbial agents;A 7 mg
B n/a
In water for 312h; Ambient temperature; A. flavipes (ATCC 16795); further microbial agents;A n/a
B 112 mg
5-[3-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-4-methylene-4,5-dihydro-isoxazol-5-yl]-10,11-dihydro-5H-dibenzo[b,f]azepine
152700-41-9

5-[3-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-4-methylene-4,5-dihydro-isoxazol-5-yl]-10,11-dihydro-5H-dibenzo[b,f]azepine

A

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

B

3-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-isoxazole-4-carbaldehyde

3-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-isoxazole-4-carbaldehyde

Conditions
ConditionsYield
With zinc(II) iodide In toluene for 6h; Heating;
5-[3-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-isoxazol-(4Z)-ylidenemethyl]-10,11-dihydro-5H-dibenzo[b,f]azepine

5-[3-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-isoxazol-(4Z)-ylidenemethyl]-10,11-dihydro-5H-dibenzo[b,f]azepine

A

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

B

3-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-isoxazole-4-carbaldehyde

3-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-isoxazole-4-carbaldehyde

Conditions
ConditionsYield
With hydrogenchloride In 1,4-dioxane for 4h; Heating;
dibenzoazepine
256-96-2

dibenzoazepine

o-toluidine
95-53-4

o-toluidine

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

Conditions
ConditionsYield
palladium on activated charcoal at 230℃; Rate constant;
2,2'-ethylenedianiline
34124-14-6

2,2'-ethylenedianiline

hydrochloride of salt of 2.2'-diamino-dibenzyl

hydrochloride of salt of 2.2'-diamino-dibenzyl

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

Conditions
ConditionsYield
at 265 - 275℃;
Imipramine hydrochloride
113-52-0

Imipramine hydrochloride

A

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

B

Dimethyl-propylidene-ammonium

Dimethyl-propylidene-ammonium

Conditions
ConditionsYield
at 280 - 326℃; Kinetics;
5-[3-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-4-methylene-4,5-dihydro-isoxazol-5-yl]-10,11-dihydro-5H-dibenzo[b,f]azepine
152700-41-9

5-[3-(3,5-Dichloro-2,4,6-trimethyl-phenyl)-4-methylene-4,5-dihydro-isoxazol-5-yl]-10,11-dihydro-5H-dibenzo[b,f]azepine

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 33 percent / ZnCl2 / toluene / 6 h / Heating
2: aq. HCl / dioxane / 4 h / Heating
View Scheme
2,2'-diaminostilbene
617-20-9

2,2'-diaminostilbene

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: isoamyl alcohol; sodium
2: 265 - 275 °C
View Scheme
Imipramine hydrochloride
113-52-0

Imipramine hydrochloride

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

Conditions
ConditionsYield
With peroxidase from horseradish type VI; dihydrogen peroxide at 37℃; for 1h; pH=7; aq. phosphate buffer; Enzymatic reaction;
2,2'-dinitrobibenzyl
16968-19-7

2,2'-dinitrobibenzyl

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: hydrogen
2: hydrogenchloride / Heating
View Scheme
9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

2,4,6,8-tetrabromoiminodibenzyl
100527-68-2

2,4,6,8-tetrabromoiminodibenzyl

Conditions
ConditionsYield
With N-Bromosuccinimide; silica gel In dichloromethane at 18℃; for 3h;100%
9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

9-bromophenanthrene
573-17-1

9-bromophenanthrene

N-(9-phenanthryl)iminodibenzyl

N-(9-phenanthryl)iminodibenzyl

Conditions
ConditionsYield
With C30H43O2P*C13H12N(1-)*CH3O3S(1-)*Pd(2+); lithium hexamethyldisilazane In 1,4-dioxane at 100℃; for 16h; Inert atmosphere;100%
1-bromo-4-methoxy-benzene
104-92-7

1-bromo-4-methoxy-benzene

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

5-(4-methoxyphenyl)-10,11-dihydro-5H-dibenzo[b,f]azepine
91222-27-4

5-(4-methoxyphenyl)-10,11-dihydro-5H-dibenzo[b,f]azepine

Conditions
ConditionsYield
With C30H43O2P*C13H12N(1-)*CH3O3S(1-)*Pd(2+); lithium hexamethyldisilazane In 1,4-dioxane at 100℃; for 16h; Inert atmosphere;100%
With potassium tert-butylate; copper(II) oxide In dimethyl sulfoxide at 80℃; for 18h; Reagent/catalyst; Inert atmosphere;91%
With potassium tert-butylate; copper(II) oxide In dimethyl sulfoxide at 80℃; for 18h; Solvent; Sealed tube; Inert atmosphere;91%
9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

allyl bromide
106-95-6

allyl bromide

5-allyl-10,11-dihydro-5H-dibenzoazepine
74074-21-8

5-allyl-10,11-dihydro-5H-dibenzoazepine

Conditions
ConditionsYield
Stage #1: 9,10-dihydrodibenzazepine With sodium hydride In N,N-dimethyl-formamide for 0.333333h; Inert atmosphere;
Stage #2: allyl bromide In N,N-dimethyl-formamide Inert atmosphere;
99%
Stage #1: 9,10-dihydrodibenzazepine With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 0.333333h; Inert atmosphere;
Stage #2: allyl bromide In N,N-dimethyl-formamide; mineral oil at 20℃; for 1h; Inert atmosphere;
92%
68%
With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate In dichloromethane; water for 72h;14%
9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

4-chloromethoxybenzene
623-12-1

4-chloromethoxybenzene

5-(4-methoxyphenyl)-10,11-dihydro-5H-dibenzo[b,f]azepine
91222-27-4

5-(4-methoxyphenyl)-10,11-dihydro-5H-dibenzo[b,f]azepine

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); 1-methyl-2-(2-(dicyclohexylphosphino)phenyl)-1H-benzoimidazole; sodium t-butanolate In toluene at 20 - 135℃; for 20h; Buchwald-Hartwig reaction; Inert atmosphere;99%
With potassium tert-butylate; copper(II) oxide In dimethyl sulfoxide at 80℃; for 18h; Inert atmosphere;87%
With potassium tert-butylate; copper(II) oxide In dimethyl sulfoxide at 80℃; for 18h; Solvent; Sealed tube; Inert atmosphere;87%
9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

chlorobenzene
108-90-7

chlorobenzene

10,11-dihydro-N-phenyldibenzazepine
78943-60-9

10,11-dihydro-N-phenyldibenzazepine

Conditions
ConditionsYield
With C30H43O2P*C13H12N(1-)*CH3O3S(1-)*Pd(2+); lithium hexamethyldisilazane In 1,4-dioxane at 100℃; for 16h; Inert atmosphere;99%
With potassium tert-butylate; copper(II) oxide In dimethyl sulfoxide at 80℃; for 18h; Inert atmosphere;80%
With potassium tert-butylate; copper(II) oxide In dimethyl sulfoxide at 80℃; for 18h; Solvent; Sealed tube; Inert atmosphere;80%
9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

dibenzoazepine
256-96-2

dibenzoazepine

Conditions
ConditionsYield
With 1-methyl-2-nitrobenzene; palladium on activated charcoal at 230℃; for 1.5h; Rate constant; Kinetics; Thermodynamic data; var. hydrogen acceptors (also without acceptor); ΔH(excit.), ΔS(excit.); var. temp. and time;98.2%
With oxygen; 2,3-dicyano-5,6-dichloro-p-benzoquinone; sodium nitrite In toluene at 120℃; under 9750.98 Torr; for 8h;24%
Stage #1: 9,10-dihydrodibenzazepine With N-Bromosuccinimide
Stage #2: With pyridine
9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

(acetylamino)acetaldehyde dimethyl acetal
62005-48-5

(acetylamino)acetaldehyde dimethyl acetal

N-(2-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)ethyl)acetamide
1262142-12-0

N-(2-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)ethyl)acetamide

Conditions
ConditionsYield
With triethylsilane; trifluoroacetic acid In dichloromethane at 20℃; for 2h; Inert atmosphere; chemoselective reaction;98%
9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

2-methylphenyl bromide
95-46-5

2-methylphenyl bromide

5-(o-tolyl)-10,11-dihydro-5H-dibenzo[b,f]azepine

5-(o-tolyl)-10,11-dihydro-5H-dibenzo[b,f]azepine

Conditions
ConditionsYield
With C30H43O2P*C13H12N(1-)*CH3O3S(1-)*Pd(2+); lithium hexamethyldisilazane In 1,4-dioxane at 100℃; for 16h; Inert atmosphere;98%
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; tris-(dibenzylideneacetone)dipalladium(0); sodium t-butanolate In toluene at 100℃; for 20h; Inert atmosphere; Sealed tube;81%
9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

1-Bromonaphthalene
90-11-9

1-Bromonaphthalene

N-(1-naphthyl)iminodibenzyl

N-(1-naphthyl)iminodibenzyl

Conditions
ConditionsYield
With C30H43O2P*C13H12N(1-)*CH3O3S(1-)*Pd(2+); lithium hexamethyldisilazane In 1,4-dioxane at 100℃; for 16h; Inert atmosphere;98%
9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

1-Bromo-4-fluorobenzene
460-00-4

1-Bromo-4-fluorobenzene

N-(4-fluorophenyl)iminodibenzyl

N-(4-fluorophenyl)iminodibenzyl

Conditions
ConditionsYield
With C30H43O2P*C13H12N(1-)*CH3O3S(1-)*Pd(2+); lithium hexamethyldisilazane In 1,4-dioxane at 100℃; for 16h; Inert atmosphere;98%
With potassium tert-butylate; copper(II) oxide In dimethyl sulfoxide at 80℃; for 18h; Reagent/catalyst; Inert atmosphere;82%
With potassium tert-butylate; copper(II) oxide In dimethyl sulfoxide at 80℃; for 18h; Solvent; Sealed tube; Inert atmosphere;82%
With nickel(II) oxide; potassium tert-butylate; triphenylphosphine In tetrahydrofuran at 100℃; for 24h; Inert atmosphere; Sealed tube; Green chemistry;73%
9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

4-bromophenethanol
4654-39-1

4-bromophenethanol

2-(4-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)phenyl)ethan-1-ol

2-(4-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)phenyl)ethan-1-ol

Conditions
ConditionsYield
With C30H43O2P*C13H12N(1-)*CH3O3S(1-)*Pd(2+); lithium hexamethyldisilazane In 1,4-dioxane at 80℃; for 16h; Inert atmosphere;98%
2-bromo-1-benzothiophene
5394-13-8

2-bromo-1-benzothiophene

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

N-(2-benzothiophenyl)iminodibenzyl

N-(2-benzothiophenyl)iminodibenzyl

Conditions
ConditionsYield
With C30H43O2P*C13H12N(1-)*CH3O3S(1-)*Pd(2+); lithium hexamethyldisilazane In 1,4-dioxane at 80℃; for 16h; Inert atmosphere;98%
9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

2,6-dimethyl-1-chlorobenzene
6781-98-2

2,6-dimethyl-1-chlorobenzene

N-(2,6-dimethylphenyl)iminodibenzyl

N-(2,6-dimethylphenyl)iminodibenzyl

Conditions
ConditionsYield
With C30H43O2P*C13H12N(1-)*CH3O3S(1-)*Pd(2+); lithium hexamethyldisilazane In 1,4-dioxane at 100℃; for 16h; Inert atmosphere;97%
2-bromo-pyridine
109-04-6

2-bromo-pyridine

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

5-(pyridin-2-yl)-10,11-dihydro-5H-dibenzo[b,f]azepine

5-(pyridin-2-yl)-10,11-dihydro-5H-dibenzo[b,f]azepine

Conditions
ConditionsYield
With C30H43O2P*C13H12N(1-)*CH3O3S(1-)*Pd(2+); lithium hexamethyldisilazane In 1,4-dioxane at 100℃; for 16h; Inert atmosphere;97%
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; tris-(dibenzylideneacetone)dipalladium(0); sodium t-butanolate In toluene at 120℃; for 48h; Inert atmosphere;75%
9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

hexanoic acid
142-62-1

hexanoic acid

5-hexyl-10,11-dihydro-5H-dibenzo[b,f]azepine hydrochloride

5-hexyl-10,11-dihydro-5H-dibenzo[b,f]azepine hydrochloride

Conditions
ConditionsYield
Stage #1: hexanoic acid With sodium tetrahydroborate In toluene at 0 - 5℃;
Stage #2: 9,10-dihydrodibenzazepine With sodium tetrahydroborate In toluene at 25 - 80℃; for 5h;
Stage #3: With hydrogenchloride In water; isopropyl alcohol
97%
9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

2,8-dibromo-10,11-dihydro-5H-dibenzo[b,f]azepine
40583-96-8

2,8-dibromo-10,11-dihydro-5H-dibenzo[b,f]azepine

Conditions
ConditionsYield
With phenyltrimethylammonium tribromide In acetonitrile at 20℃; for 4h; Inert atmosphere;96%
With N-Bromosuccinimide In chloroform at 0 - 20℃; for 1h; Darkness;78%
With N-Bromosuccinimide In dichloromethane; N,N-dimethyl-formamide at 20℃; for 1h;63%
With N-Bromosuccinimide In chloroform at 0 - 25℃; for 2h; Inert atmosphere;41%
With N-Bromosuccinimide; silica gel In dichloromethane at 18℃; for 0.2h; Yield given;

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

10,11-dihydro-N-phenyldibenzazepine
78943-60-9

10,11-dihydro-N-phenyldibenzazepine

Conditions
ConditionsYield
With C30H43O2P*C13H12N(1-)*CH3O3S(1-)*Pd(2+); lithium hexamethyldisilazane In 1,4-dioxane at 100℃; for 16h; Inert atmosphere;96%
With potassium tert-butylate; copper(II) oxide In dimethyl sulfoxide at 80℃; for 18h; Solvent; Sealed tube; Inert atmosphere;95%
With potassium tert-butylate; copper(II) oxide In dimethyl sulfoxide at 80℃; for 18h; Catalytic behavior; Reagent/catalyst; Solvent; Temperature; Inert atmosphere;90%
9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

N-(2-biphenyl)iminodibenzyl

N-(2-biphenyl)iminodibenzyl

Conditions
ConditionsYield
With C30H43O2P*C13H12N(1-)*CH3O3S(1-)*Pd(2+); lithium hexamethyldisilazane In 1,4-dioxane at 100℃; for 16h; Inert atmosphere;96%
9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

9-Bromoanthracene
1564-64-3

9-Bromoanthracene

5-(anthracen-9-yl)-10,11-dihydro-5H-dibenzo[b,f]azepine

5-(anthracen-9-yl)-10,11-dihydro-5H-dibenzo[b,f]azepine

Conditions
ConditionsYield
With C30H43O2P*C13H12N(1-)*CH3O3S(1-)*Pd(2+); lithium hexamethyldisilazane In 1,4-dioxane at 100℃; for 16h; Inert atmosphere;96%
With tris-(dibenzylideneacetone)dipalladium(0); lithium hexamethyldisilazane; ruphos In 1,4-dioxane at 100℃; for 24h; Inert atmosphere; Schlenk technique; Sealed tube;75%
5-bromo-1H-indole
10075-50-0

5-bromo-1H-indole

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

N-(5-indolyl)iminodibenzyl

N-(5-indolyl)iminodibenzyl

Conditions
ConditionsYield
With C30H43O2P*C13H12N(1-)*CH3O3S(1-)*Pd(2+); lithium hexamethyldisilazane In 1,4-dioxane at 80℃; for 16h; Inert atmosphere;96%
9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

chloroacetyl chloride
79-04-9

chloroacetyl chloride

2-chloro-1-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)ethan-1-one
3534-05-2

2-chloro-1-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)ethan-1-one

Conditions
ConditionsYield
In toluene at 90℃; for 4h; Inert atmosphere;95%
In toluene for 5h; Heating;53%
In toluene Heating;
With benzene
9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

acetic anhydride
108-24-7

acetic anhydride

5-acetyliminodibenzyl
13080-75-6

5-acetyliminodibenzyl

Conditions
ConditionsYield
for 3h; Reflux;95%
With acetic acid at 110℃; for 2h;84%
9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

para-chlorotoluene
106-43-4

para-chlorotoluene

5-(4-methylphenyl)-10,11-dihydro-5H-dibenzo[b,f]azepine
155162-78-0

5-(4-methylphenyl)-10,11-dihydro-5H-dibenzo[b,f]azepine

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); 1-methyl-2-(2-(dicyclohexylphosphino)phenyl)-1H-benzoimidazole; sodium t-butanolate In toluene at 20 - 135℃; for 20h; Buchwald-Hartwig reaction; Inert atmosphere;94%
With potassium tert-butylate; copper(II) oxide In dimethyl sulfoxide at 80℃; for 18h; Inert atmosphere;81%
With potassium tert-butylate; copper(II) oxide In dimethyl sulfoxide at 80℃; for 18h; Solvent; Sealed tube; Inert atmosphere;81%
9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

2-Bromo-m-xylene
576-22-7

2-Bromo-m-xylene

N-(2,6-dimethylphenyl)iminodibenzyl

N-(2,6-dimethylphenyl)iminodibenzyl

Conditions
ConditionsYield
With C30H43O2P*C13H12N(1-)*CH3O3S(1-)*Pd(2+); lithium hexamethyldisilazane In 1,4-dioxane at 100℃; for 16h; Reagent/catalyst; Inert atmosphere;94%
9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

o-trifluoromethylphenyl bromide
392-83-6

o-trifluoromethylphenyl bromide

N-[2-(trifluoromethyl)phenyl]iminodibenzyl

N-[2-(trifluoromethyl)phenyl]iminodibenzyl

Conditions
ConditionsYield
With C30H43O2P*C13H12N(1-)*CH3O3S(1-)*Pd(2+); lithium hexamethyldisilazane In 1,4-dioxane at 100℃; for 16h; Inert atmosphere;94%
9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

5-(cyano)dibenzothiophenium triflate

5-(cyano)dibenzothiophenium triflate

10,11-dihydro-5H-dibenzo[b,f]azepine-5-carbonitrile

10,11-dihydro-5H-dibenzo[b,f]azepine-5-carbonitrile

Conditions
ConditionsYield
With caesium carbonate In dichloromethane at 20℃; for 8h; Inert atmosphere;94%
morpholine
110-91-8

morpholine

formaldehyd
50-00-0

formaldehyd

9,10-dihydrodibenzazepine
494-19-9

9,10-dihydrodibenzazepine

bis(morpholinomethyl)-2,8 dihydro-10,11 5H dibenzoazepine
64097-61-6

bis(morpholinomethyl)-2,8 dihydro-10,11 5H dibenzoazepine

Conditions
ConditionsYield
With acetic acid for 30h; Heating;93%
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