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YUNBIO TECH CO.,LTD

Our Strength: -Flexible: We work in small teams with rapid communication channels. Respond quickly and efficiently to customer and market needs. -Innovative: We are focusing on the development of new products and keep close relationships with

5-Iodo-2-Deoxyuridine 5-IDU CAS NO.54-42-2 Pharma intermediate worldwide TOP pharma factory vendor

Cas:54-42-2

Min.Order:1 Kilogram

FOB Price: $2000.0 / 2500.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 5-Iodo-2'-Deoxyuridine supplier in China

Cas:54-42-2

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay 99.9%min 99.9% Hangzhou Dingyan Chem is a leading manufacturer and supplier of che

High quality 54-42-2 (+)-5-Iodo-2'-deoxyuridine

Cas:54-42-2

Min.Order:1 Kilogram

FOB Price: $1300.0 / 1600.0

Type:Trading Company

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Kono Chem Co.,Ltd

fine chemical white to light yellow powder Idoxuridine CAS 54-42-2 MF C9H11IN2O5 mw 354.10 354.10 dentification: White crystalline powder

CAS: 54-42-2 2'-Deoxy-5-iodouridine

Cas:54-42-2

Min.Order:1 Kilogram

Negotiable

Type:Other

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Wuhan Fortuna Chemical Co.,Ltd

Manufacturer supply 5-Iodo-2'-deoxyuridine CAS 54-42-2 Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives,

Manufacturer supply 5-Iodo-2'-deoxyuridine CAS 54-42-2

Cas:54-42-2

Min.Order:1 Gram

FOB Price: $10.0

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:white powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

(+)-5-Iodo-2'-deoxyuridine

Cas:54-42-2

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 5-Iodo-2'-Deoxyuridine

Cas:54-42-2

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% Idoxuridine 54-42-2 GMP Manufacturer

Cas:54-42-2

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality Idoxuridine

Cas:54-42-2

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

(+)-5-Iodo-2'-deoxyuridine Manufacturer/High quality/Best price/In stock

Cas:54-42-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Idoxuridine

Cas:54-42-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

discount (+)-5-Iodo-2'-deoxyuridine

Cas:54-42-2

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

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LIDE PHARMACEUTICALS LIMITED

LIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.

(+)-5-Iodo-2'-deoxyuridine

Cas:54-42-2

Min.Order:1 Kilogram

FOB Price: $0.9 / 1.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

54-42-2 Idoxuridine

Cas:54-42-2

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 54-42-2 with best quality

Cas:54-42-2

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

(+)-5-Iodo-2'-deoxyuridine CAS No.54-42-2

Cas:54-42-2

Min.Order:10 Kilogram

FOB Price: $20.0 / 40.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Molecular formula: C9H11IN2O5 Molecular weight: 354.10 CAS No.: 54-42-2 Identification: White crystalline powder Appearance:White powder Storage: Room T

(+)-5-Iodo-2'-deoxyuridine CAS: 54-42-2

Cas:54-42-2

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

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Hangzhou Sartort Biopharma Co., Ltd

Appearance:white crystalline solid Storage:Room temperature Package:25kg/drum Application:Antiviral Transportation:Express/Sea/Air Port:Any port in china

High Quality (+)-5-Iodo-2'-deoxyuridine 5-IDU

Cas:54-42-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

(+)-5-Iodo-2'-deoxyuridine 54-42-2

Cas:54-42-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

5-IDU/CAS:54-42-2

Cas:54-42-2

Min.Order:1 Gram

FOB Price: $227.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

Idoxuridine CAS:54-42-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates, s

Idoxuridine CAS:54-42-2

Cas:54-42-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

5-Iodo-2'-deoxyuridine

Cas:54-42-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

(+)-5-Iodo-2'-deoxyuridine

Cas:54-42-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

(+)-5-Iodo-2'-deoxyuridine

Cas:54-42-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

(+)-5-Iodo-2'-deoxyuridine

Cas:54-42-2

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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NewCan Biotech Limited

NewCan Biotech Limited was established in 2021 and is primarily engaged in the research, development, production, and sales of sugars, nucleosides, nucleotides, phosphorylated monomers, as well as next-generation antiviral and antitumor drug intermed

5-Iodo-2'-deoxyuridine

Cas:54-42-2

Min.Order:1 Milligram

Negotiable

Type:Trading Company

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SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione

Cas:54-42-2

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

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Saiwante (shanghai) New Material Technology Co., Ltd.

ProName: High quality 5-Iodo-2'-Deoxyuridine su... CasNo: 54-42-2 Molecular Formula: C9H11IN2O5 Appearance: white-off solid or colorless liquid ( ... Application: Specialty chemical DeliveryTime: Instock PackAge: 25kgs/fiber drum or 200kg

High quality 5-Iodo-2'-Deoxyuridine supplier in China CAS NO. 54-42-2

Cas:54-42-2

Min.Order:1 Gram

FOB Price: $5.0 / 6.0

Type:Trading Company

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

(+)-5-Iodo-2'-deoxyuridine

Cas:54-42-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

2'-deoxyuridine
951-78-0

2'-deoxyuridine

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

Conditions
ConditionsYield
With iodine; silver nitrate In methanol at 40℃; for 3h;100%
With iodine; silver nitrate In methanol at 40℃; for 3h;100%
With sodium azide; Iodine monochloride In acetonitrile at 25℃; for 24h; Product distribution; Mechanism; other uracil nucleosides; other halogenation agents; var. temp. and time;96%
3',5'-O-diacetyl-5-iodo-2'-deoxyuridine
1956-30-5

3',5'-O-diacetyl-5-iodo-2'-deoxyuridine

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

Conditions
ConditionsYield
With sodium methylate In methanol for 1h; Ambient temperature;90%
With methanol; sodium methylate at 20℃; for 1h;
5-trimethylstannyl-2'-deoxyuridine
146629-34-7

5-trimethylstannyl-2'-deoxyuridine

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

Conditions
ConditionsYield
With sodium hydroxide; dihydrogen peroxide; acetic acid; sodium iodide In chloroform for 0.00416667h; Irradiation;
C23H17Cl2IN2O7

C23H17Cl2IN2O7

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

Conditions
ConditionsYield
With ammonia In methanol at 30℃; for 16h;
2'-deoxyuridine
951-78-0

2'-deoxyuridine

5-iodouracil
696-07-1

5-iodouracil

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

Conditions
ConditionsYield
at 37℃; for 6h; alginate gel-entrapped cells of auxotrophic thymine-dependent strain of E. coli, ammonium acetate buffer pH 5.8;
5-iodouracil
696-07-1

5-iodouracil

thymidine
50-89-5

thymidine

A

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

B

thymin
65-71-4

thymin

Conditions
ConditionsYield
With thymidine phosphorylase from Escherichia coli In phosphate buffer at 35℃; for 2h; pH=7.0; Title compound not separated from byproducts;A 88 % Chromat.
B n/a
3',5'-di-O-acetyl-2'-deoxyuridine
13030-62-1

3',5'-di-O-acetyl-2'-deoxyuridine

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 93 percent / LiI, ceric ammonium nitrate (CAN) / acetonitrile / 1 h / 80 °C / other conditions and reagents investigated
2: 90 percent / 0.1 M NaOMe / methanol / 1 h / Ambient temperature
View Scheme
C5-chloromercuri-2'-deoxyuridine
65505-76-2

C5-chloromercuri-2'-deoxyuridine

1,3,4,6-tetrachloro-3α,6α-diphenyl glycoluril
51592-06-4

1,3,4,6-tetrachloro-3α,6α-diphenyl glycoluril

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

Conditions
ConditionsYield
With sodium iodide In water
2'-deoxyuridine
951-78-0

2'-deoxyuridine

5-iodouracil
696-07-1

5-iodouracil

A

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

B

uracil
66-22-8

uracil

Conditions
ConditionsYield
With thymidine phosphorylase from Escherichia coli (E.C. 2.4.2.4) immobilized on Sepabeads EC-EP In aq. phosphate buffer at 20℃; for 3h; pH=7.5; Reagent/catalyst; Enzymatic reaction;
3',5'-di-O-acetyl-2'-deoxyuridine
13030-62-1

3',5'-di-O-acetyl-2'-deoxyuridine

A

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

B

C9H11IN2O5S

C9H11IN2O5S

C

C18H20I2N4O8S2

C18H20I2N4O8S2

D

C18H21IN4O8S2

C18H21IN4O8S2

E

2'-deoxy-4-thiouridine
5580-20-1

2'-deoxy-4-thiouridine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: ammonium cerium (IV) nitrate; iodine / acetonitrile / 1 h / 80 °C
2: tetraphosphorus decasulfide / 1,4-dioxane / Reflux
3: sodium hydride / methanol / 0.17 h / 0 - 20 °C
4: aq. phosphate buffer; tert-butyl alcohol / Radiolysis
View Scheme
3',5'-O-diacetyl-5-iodo-2'-deoxyuridine
1956-30-5

3',5'-O-diacetyl-5-iodo-2'-deoxyuridine

A

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

B

C9H11IN2O5S

C9H11IN2O5S

C

C18H20I2N4O8S2

C18H20I2N4O8S2

D

C18H21IN4O8S2

C18H21IN4O8S2

E

2'-deoxy-4-thiouridine
5580-20-1

2'-deoxy-4-thiouridine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: tetraphosphorus decasulfide / 1,4-dioxane / Reflux
2: sodium hydride / methanol / 0.17 h / 0 - 20 °C
3: aq. phosphate buffer; tert-butyl alcohol / Radiolysis
View Scheme
5-iodo-4-thio-2'-deoxyuridine
1313407-40-7

5-iodo-4-thio-2'-deoxyuridine

A

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

B

C9H11IN2O5S

C9H11IN2O5S

C

C18H20I2N4O8S2

C18H20I2N4O8S2

D

C18H21IN4O8S2

C18H21IN4O8S2

E

2'-deoxy-4-thiouridine
5580-20-1

2'-deoxy-4-thiouridine

Conditions
ConditionsYield
In aq. phosphate buffer; tert-butyl alcohol Radiolysis;
2'-deoxyuridine
951-78-0

2'-deoxyuridine

A

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

B

C9H11IN2O5S

C9H11IN2O5S

C

C18H20I2N4O8S2

C18H20I2N4O8S2

D

C18H21IN4O8S2

C18H21IN4O8S2

E

2'-deoxy-4-thiouridine
5580-20-1

2'-deoxy-4-thiouridine

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: pyridine / 24 h / 20 °C
2: ammonium cerium (IV) nitrate; iodine / acetonitrile / 1 h / 80 °C
3: tetraphosphorus decasulfide / 1,4-dioxane / Reflux
4: sodium hydride / methanol / 0.17 h / 0 - 20 °C
5: aq. phosphate buffer; tert-butyl alcohol / Radiolysis
View Scheme
5-iodouracil
696-07-1

5-iodouracil

thymidine
50-89-5

thymidine

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

Conditions
ConditionsYield
With recobinant purine nucleoside phosphorylase from Escherichia coli In aq. phosphate buffer pH=6.8; Heating; Enzymatic reaction;
C5H9O7P(2-)*2K(1+)

C5H9O7P(2-)*2K(1+)

5-iodouracil
696-07-1

5-iodouracil

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

Conditions
ConditionsYield
With E-pyrimidine nucleoside phosphorylase-0002 In aq. buffer at 50℃; for 2h; pH=9; Equilibrium constant; Enzymatic reaction;
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

acrylic acid methyl ester
292638-85-8

acrylic acid methyl ester

methyl (E)-3-(1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylate
86163-17-9

methyl (E)-3-(1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylate

Conditions
ConditionsYield
With palladium diacetate; triethylamine; triphenylphosphine In 1,4-dioxane for 14h; Heating;100%
Stage #1: 5-Iodo-2'-deoxyuridine With C26H32N8O6P2PdS2 In acetonitrile at 80℃; for 0.0833333h; Heck Reaction; Inert atmosphere;
Stage #2: acrylic acid methyl ester With triethylamine In acetonitrile at 80℃; for 8h; Heck Reaction; Inert atmosphere;
92%
With palladium diacetate; triethylamine; triphenylphosphine In N,N-dimethyl-formamide at 100℃; for 1h;87%
9-ethynyl-closo-1,7-dodecaborane
80755-88-0

9-ethynyl-closo-1,7-dodecaborane

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

5-[(1,7-dicarba-closo-dodecaboran-9-yl)ethyn-1-yl]-2′-deoxyuridine

5-[(1,7-dicarba-closo-dodecaboran-9-yl)ethyn-1-yl]-2′-deoxyuridine

Conditions
ConditionsYield
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); triethylamine In N,N-dimethyl-formamide at 80℃; Sonogashira Cross-Coupling; Inert atmosphere;100%
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

2'-deoxy-3',5'-bis(O-tert-butyldimethylsilyl)-5-iodouridine
148134-86-5

2'-deoxy-3',5'-bis(O-tert-butyldimethylsilyl)-5-iodouridine

Conditions
ConditionsYield
With 1H-imidazole In pyridine for 33h;99%
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 3h;99.8%
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 60h;99%
4,4'-dimethoxytrityl chloride
40615-36-9

4,4'-dimethoxytrityl chloride

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-5-iodouridine
104375-88-4

2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-5-iodouridine

Conditions
ConditionsYield
With pyridine Ambient temperature;99%
With pyridine; triethylamine at 20℃; for 1h;98%
With pyridine In triethylamine at 20℃; for 5h;96%
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

acetic anhydride
108-24-7

acetic anhydride

3',5'-O-diacetyl-5-iodo-2'-deoxyuridine
1956-30-5

3',5'-O-diacetyl-5-iodo-2'-deoxyuridine

Conditions
ConditionsYield
With pyridine at 20℃; for 16.5h;99%
With pyridine at 20℃;98%
With pyridine at 25℃; for 20h;97%
3,3-bis-(trifluoromethyl)-4,4,4-trifluoro-1-butyne
14115-48-1

3,3-bis-(trifluoromethyl)-4,4,4-trifluoro-1-butyne

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

5-(4,4,4-trifluoro-3,3-bis(trifluoromethyl)but-1-ynyl)-2'-deoxyuridine
1032735-58-2

5-(4,4,4-trifluoro-3,3-bis(trifluoromethyl)but-1-ynyl)-2'-deoxyuridine

Conditions
ConditionsYield
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 22℃; for 96h; Sonogashira coupling; Inert atmosphere;98%
acrylic acid n-butyl ester
141-32-2

acrylic acid n-butyl ester

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

(E)-5-[2-(n-butyloxycarbonyl)vinyl]-2′-deoxyuridine

(E)-5-[2-(n-butyloxycarbonyl)vinyl]-2′-deoxyuridine

Conditions
ConditionsYield
With 3,3′,3″-phosphinetriyltribenzenesulfonate; palladium diacetate; triethylamine In water; acetonitrile at 80℃; for 1.5h; Solvent; Temperature; Reagent/catalyst; Inert atmosphere;98%
With tri(3-sulfonatophenyl)phosphine trisodium salt; palladium diacetate; triethylamine In water; acetonitrile at 80℃; Heck reaction; Inert atmosphere;74%
methanol
67-56-1

methanol

carbon monoxide
201230-82-2

carbon monoxide

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

5-methoxycarbonyl-2’-deoxyuridine

5-methoxycarbonyl-2’-deoxyuridine

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); triethylamine; triphenylphosphine In N,N-dimethyl-formamide at 70℃;98%
1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane
69304-37-6

1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

5-iodo-3',5'-O-[(tetraisopropyl)disiloxane-1,3-diyl]-2'-deoxyuridine
129507-76-2

5-iodo-3',5'-O-[(tetraisopropyl)disiloxane-1,3-diyl]-2'-deoxyuridine

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide for 12h;97%
With pyridine at 20℃;97%
With pyridine at 20℃;84%
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 3h; silylation;
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

phenylboronic acid
98-80-6

phenylboronic acid

1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-phenylpyrimidine-2,4(1H,3H)-dione
76756-28-0

1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-phenylpyrimidine-2,4(1H,3H)-dione

Conditions
ConditionsYield
With palladium diacetate; sodium carbonate; triphenylphosphine In water; acetonitrile at 70 - 80℃; for 4h; Suzuki-Miyaura Coupling; Inert atmosphere;97%
With palladium diacetate; sodium carbonate; triphenylphosphine In water; acetonitrile at 70 - 80℃; for 4h; Suzuki-Miyaura Coupling; Inert atmosphere;97%
With C30H24Cl2N2O10Pd2S2(2-)*2Na(1+); triethylamine In water at 60℃; for 3h; Suzuki-Miyaura Coupling; Inert atmosphere; Schlenk technique;93%
2-ethynylpyridine
1945-84-2

2-ethynylpyridine

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

5-(2-pyridylethynyl)-2'-deoxyuridine
78824-48-3

5-(2-pyridylethynyl)-2'-deoxyuridine

Conditions
ConditionsYield
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; Inert atmosphere;97%
1-Heptene
592-76-7

1-Heptene

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

5-(hept-1-en-1-yl)-2'-deoxyuridine
96962-44-6

5-(hept-1-en-1-yl)-2'-deoxyuridine

Conditions
ConditionsYield
With tributyl-amine; palladium diacetate In N,N-dimethyl-formamide at 100℃; for 0.333333h; Heck reaction; Microwave irradiation;97%
With tributyl-amine; palladium diacetate In 1,4-dioxane; N,N-dimethyl-formamide at 100℃; for 0.333333h; Microwave irradiation;97%
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

2-(tri-n-butylstannyl)benzofuran

2-(tri-n-butylstannyl)benzofuran

5-(benzofuran-2-yl)-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
1449768-52-8

5-(benzofuran-2-yl)-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride In 1,4-dioxane at 90℃; Stille Cross Coupling;97%
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

but-1-yn-4-yl thiobenzoate
211510-45-1

but-1-yn-4-yl thiobenzoate

5-(4-benzoylthio-1-butynyl)-2'-deoxyuridine
647852-33-3

5-(4-benzoylthio-1-butynyl)-2'-deoxyuridine

Conditions
ConditionsYield
With copper(l) iodide; triethylamine; tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide at 22 - 24℃;96%
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

acetyl chloride
75-36-5

acetyl chloride

3',5'-O-diacetyl-5-iodo-2'-deoxyuridine
1956-30-5

3',5'-O-diacetyl-5-iodo-2'-deoxyuridine

Conditions
ConditionsYield
With acetic anhydride; acetic acid 1.) 0 deg C, 1 h, 2.) RT, 24 h;95%
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

dimethyl sulfate
77-78-1

dimethyl sulfate

5-iodo-3-methyl-2′-deoxyuridine
35695-25-1

5-iodo-3-methyl-2′-deoxyuridine

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran at 20℃; for 0.166667h;95%
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

3-methyl-N-(prop-2-yn-1-yl)butanamide
422284-33-1

3-methyl-N-(prop-2-yn-1-yl)butanamide

5-[3-(3-methylbutyrylamino)prop-1-ynyl]-2'-deoxyuridine

5-[3-(3-methylbutyrylamino)prop-1-ynyl]-2'-deoxyuridine

Conditions
ConditionsYield
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); triethylamine In N,N-dimethyl-formamide at 20℃; for 4h;95%
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

diphenylphosphane
829-85-6

diphenylphosphane

5-diphenylphosphine-2'-deoxyuridine
939057-19-9

5-diphenylphosphine-2'-deoxyuridine

Conditions
ConditionsYield
With triethylamine; palladium diacetate In N,N-dimethyl-formamide at 60℃; for 0.5h;95%
3-methoxyphenylboronic acid
10365-98-7

3-methoxyphenylboronic acid

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

5-(3-methoxyphenyl)-2'-deoxyuridine
92510-79-7

5-(3-methoxyphenyl)-2'-deoxyuridine

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); cesium fluoride In water; N,N-dimethyl-formamide at 60℃; Suzuki cross-coupling; Inert atmosphere;95%
With [Pd(phthalimidate)2(1,3,5-triaza-7-phosphaadamantane)2]; triethylamine In water at 20 - 80℃; for 6h; Suzuki-Miyaura Coupling; Inert atmosphere;
4-tert-Butylphenylacetylene
772-38-3

4-tert-Butylphenylacetylene

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

5-((4-tert-butylphenyl)ethynyl)-2'-deoxyuridine
596107-17-4

5-((4-tert-butylphenyl)ethynyl)-2'-deoxyuridine

Conditions
ConditionsYield
With copper(l) iodide; triethylamine; tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide at 40℃; for 25h; Sonogashira coupling;94%
With copper(l) iodide; tetra-(n-butyl)ammonium iodide; triphenylphosphine; tetrakis(triphenylphosphine) palladium(0); triethylamine In N,N-dimethyl-formamide at 20℃; for 24h; Sonogashira coupling;76%
With copper(l) iodide; triethylamine; tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

2-(tributylstannyl)furan
118486-94-5

2-(tributylstannyl)furan

5-furan-2-yl-1-(β-D-2-deoxyribofuranos-1-yl)uracil
92233-50-6

5-furan-2-yl-1-(β-D-2-deoxyribofuranos-1-yl)uracil

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride In 1,4-dioxane at 90℃; for 2h; Stille coupling;94%
bis-triphenylphosphine-palladium(II) chloride In 1,4-dioxane at 90℃; for 2h; Stille coupling;94%
With bis-triphenylphosphine-palladium(II) chloride In 1,4-dioxane94%
With bis-triphenylphosphine-palladium(II) chloride In 1,4-dioxane at 90℃; Stille Cross Coupling;
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

1-Ethynyl-1-cyclohexanol
78-27-3

1-Ethynyl-1-cyclohexanol

5-((1-hydroxycyclohexyl)ethynyl)-2'-deoxyuridine
936332-87-5

5-((1-hydroxycyclohexyl)ethynyl)-2'-deoxyuridine

Conditions
ConditionsYield
With copper(l) iodide; triethylamine; tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide at 50℃; for 7h; Sonogashira coupling;94%
With copper(l) iodide; triethylamine; tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide
2-Methylphenylboronic acid
16419-60-6

2-Methylphenylboronic acid

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

5-(2-methylphenyl)-2'-deoxyuridine
1373213-45-6

5-(2-methylphenyl)-2'-deoxyuridine

Conditions
ConditionsYield
With sodium tetrachloropalladate; trisodium tris(3-sulfophenyl)phosphine; potassium hydroxide In water at 100℃; for 24h; Suzuki-Miyaura coupling; Inert atmosphere;94%
With sodium tetrachloropalladate(II); potassium hydroxide In water at 100℃; for 1h; Suzuki-Miyaura Coupling; Inert atmosphere; Microwave irradiation;30%
With sodium tetrachloropalladate(II); potassium hydroxide In water at 100℃; for 24h; Concentration; Time; Suzuki-Miyaura Coupling; Inert atmosphere; Green chemistry;22%
benzofuran-2-boronic acid
98437-24-2

benzofuran-2-boronic acid

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

5-(benzofuran-2-yl)-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
1449768-52-8

5-(benzofuran-2-yl)-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

Conditions
ConditionsYield
With [Pd(succinimidate)2(1,3,5-triaza-7-phosphaadamantane)2]; triethylamine In water at 80℃; for 0.0833333h; Catalytic behavior; Concentration; Suzuki-Miyaura Coupling; Microwave irradiation; Inert atmosphere;94%
With C30H24Cl2N2O10Pd2S2(2-)*2Na(1+); triethylamine In water at 60℃; for 3h; Solvent; Reagent/catalyst; Temperature; Suzuki-Miyaura Coupling; Inert atmosphere; Schlenk technique;89%
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

propionic acid anhydride
123-62-6

propionic acid anhydride

3′,5′-bis-O-propionyl-5-iodo-2′-deoxyuridine
4833-05-0

3′,5′-bis-O-propionyl-5-iodo-2′-deoxyuridine

Conditions
ConditionsYield
With pyridine at 60℃; for 8h; Inert atmosphere;93%
With pyridine85%
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

tri-n-butyl(vinyl)tin
7486-35-3

tri-n-butyl(vinyl)tin

5-vinyl-2'-deoxyuridine
55520-67-7

5-vinyl-2'-deoxyuridine

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran for 12h; Inert atmosphere; Reflux;92%
With bis-triphenylphosphine-palladium(II) chloride In tetrahydrofuran for 24h; Inert atmosphere; Reflux;50%
With bis-triphenylphosphine-palladium(II) chloride In tetrahydrofuran for 24h; Heating;47%
5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

trimethylsilylacetylene
1066-54-2

trimethylsilylacetylene

1-(2-deoxy-β-D-ribofuranosyl)-5-[2-(trimethylsilyl)ethynyl]uracil
151362-01-5

1-(2-deoxy-β-D-ribofuranosyl)-5-[2-(trimethylsilyl)ethynyl]uracil

Conditions
ConditionsYield
With copper(l) iodide; triethylamine; tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide at 55℃; for 24h; Sonogashira coupling;92%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In acetonitrile at 50℃; for 3.5h; Schlenk technique; Inert atmosphere;85%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In acetonitrile for 3.5h; Inert atmosphere; Heating;82%
4-fluoroboronic acid
1765-93-1

4-fluoroboronic acid

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

5-(4'-fluorophenyl)-2'-deoxyuridine

5-(4'-fluorophenyl)-2'-deoxyuridine

Conditions
ConditionsYield
With palladium diacetate; sodium carbonate; tris-(m-sulfonatophenyl)phosphine In water; acetonitrile at 80℃; Suzuki coupling;92%
With tetrakis(triphenylphosphine) palladium(0); cesium fluoride In water; N,N-dimethyl-formamide at 60℃; Suzuki cross-coupling; Inert atmosphere;78%
With palladium diacetate; sodium carbonate; triphenylphosphine In water at 120℃; for 0.166667h; Suzuki-Miyaura Coupling; Inert atmosphere; Sealed tube; Microwave irradiation;74%
With [Pd(phthalimidate)2(1,3,5-triaza-7-phosphaadamantane)2]; triethylamine In water at 20 - 80℃; for 6h; Suzuki-Miyaura Coupling; Inert atmosphere;
methyl 3-ethynylbenzoate
10602-06-9

methyl 3-ethynylbenzoate

5-Iodo-2'-deoxyuridine
54-42-2

5-Iodo-2'-deoxyuridine

3-[3-((2R,4S,5R)-4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-oxo-2,3-dihydro-furo[2,3-d]pyrimidin-6-yl]-benzoic acid methyl ester

3-[3-((2R,4S,5R)-4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-oxo-2,3-dihydro-furo[2,3-d]pyrimidin-6-yl]-benzoic acid methyl ester

Conditions
ConditionsYield
With copper(l) iodide; triethylamine; tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 55℃; for 12h;92%
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