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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

p-(2-Methoxyethyl) phenol Manufacturer/High quality/Best price/In stock

Cas:56718-71-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 4-(2-Methoxyethyl)-Phenol supplier in China

Cas:56718-71-9

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

p-(2-Methoxyethyl) phenol Manufacturer/High quality/Best price/In stock CAS NO.56718-71-9

Cas:56718-71-9

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Manufacturers

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

p-(2-Methoxyethyl) phenol

Cas:56718-71-9

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply p-(2-methoxyethyl)phenol

Cas:56718-71-9

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Phenol,4-(2-methoxyethyl)- 56718-71-9 ISO Manufacturer

Cas:56718-71-9

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi

4-(2-Methoxyethyl)-phenol

Cas:56718-71-9

Min.Order:10 Kilogram

FOB Price: $1.0 / 11.0

Type:Manufacturers

inquiry

COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

P-(2-Methoxyethyl) Phenol

Cas:56718-71-9

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

4-(2-Methoxyethyl)-phenol

Cas:56718-71-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hubei DiBo chemical co., LTD

Name:4-(2-Methoxyethyl)phenol CAS NO: 56718-71-9 Grade:Medical scientific research and export Molecular formula:C9H12O2 Molecular weight:152.1904 Product Quality 12 years of chemical raw materials Mature operation of the industry System st

4-(2-Methoxyethyl)phenol/cas:56718-71-9/Raw material spot

Cas:56718-71-9

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

p-(2-Methoxyethyl) phenol

Cas:56718-71-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

p-(2-Methoxyethyl) phenol

Cas:56718-71-9

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 56718-71-9 with best quality

Cas:56718-71-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

p-(2-Methoxyethyl) phenol/P-ethyl ether

Cas:56718-71-9

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

English name p-(2-Methoxyethyl) phenol English alias 4-(2-Methoxyethyl)-phenol CAS RN 56718-71-9 Molecular formula C9H12O2 Molecular weight 152.19 Content 98% Appearance:Wh

p-(2-Methoxyethyl) phenol CAS:56718-71-9

Cas:56718-71-9

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Phenol,4-(2-methoxyethyl)- 56718-71-9

Cas:56718-71-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

p-(2-Methoxyethyl) phenol CAS:56718-71-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic

p-(2-Methoxyethyl) phenol CAS:56718-71-9

Cas:56718-71-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Phenol,4-(2-methoxyethyl)-

Cas:56718-71-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Mojin Biotechnology Co.,Ltd

Hebei Mojin Biotechnology Co., Ltd, Our company is a professional chemical raw materials and chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, Am

4-(2-Methoxyethyl)phenol cas 56718-71-9 p-(2-Methoxyethyl) phenol

Cas:56718-71-9

Min.Order:1 Kilogram

FOB Price: $170.0 / 180.0

Type:Trading Company

inquiry

Wuhan Zenuo Biological Medicine Technology Co Ltd

Product Name: p-(2-Methoxyethyl) phenol Synonyms: Metoprolol-2;Imp. B (EP):4-(2-Methoxyethyl)phenol;Metoprolol-EP-Imp-B;P-ethyl ether;P-Methyl ether;Metoprolol Tartrate EP IMpurity-B;Metoprolol EP IMpurity B;Phenol,4-(2-Methoxyethyl)- CAS: 567

p-(2-Methoxyethyl) phenol big supplier with lower price

Cas:56718-71-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Lonwin Chemical Group Limited

P-(2-Methoxyethyl) Phenol CAS: 56718-71-9 Specification Item Standard Identification A.H-NMR:Comply with the structure B.LC-MS:Comply with the structure C.The I

Factory supply P-(2-Methoxyethyl) Phenol

Cas:56718-71-9

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Phenol,4-(2-methoxyethyl)-

Cas:56718-71-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

P-(2-Methoxyethyl) Phenol

Cas:56718-71-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Triumph International Development Limilted

Appearance:white powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:Common products:Sea/Air/Courie

4-(2-Methoxyethyl)phenol

Cas:56718-71-9

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

high purity 4-(2-Methoxyethyl)phenol cas no.56718-71-9

Cas:56718-71-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures

4-(2-Methoxyethyl)phenol

Cas:56718-71-9

Min.Order:1 Kilogram

FOB Price: $40.0 / 50.0

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

4-(2-Methoxyethyl) phenol

Cas:56718-71-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

p-(2-Methoxyethyl) phenol

Cas:56718-71-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Send Pharmaceutical Technology Co., Ltd.

lower price and high quality Appearance:white Storage:Preserve In Well-Closed, Light-Resistant and Tight Containers. Store In Cool & Dry Place Package:1g,5g,10g...1kg,5kg...more Application:Pharmaceutical Intermediate Transportation:shipping,land,a

4-(2-Methoxyethyl)-Phenol

Cas:56718-71-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

p-(2-Methoxyethyl) phenolL/High quality/Best price

Cas:56718-71-9

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Synthetic route

alpha-methoxy-4-hydroxyacetophenone
32136-81-5

alpha-methoxy-4-hydroxyacetophenone

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In ethanol under 2327.2 Torr; for 4h;96%
With hydrogen under 3000.3 Torr; Pressure; Heating;80%
With hydrogen; acetic acid; palladium on activated charcoal
With H2; acetic acid; palladium-carbon0.54 g (3.6 mmol=61%)
4-hydroxyphenyl glyoxal dimethylacetal

4-hydroxyphenyl glyoxal dimethylacetal

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
palladium-carbon In hydrogenchloride; methanol70%
With hydrogen; palladium-carbon In hydrogenchloride; methanol59%
With hydrogen; palladium-carbon In methanol53%
With hydrogenchloride; hydrogen; palladium-carbon In methanol47%
p-hydroxyphenethyl alcohol
501-94-0

p-hydroxyphenethyl alcohol

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
With sulfuric acid In methanol40%
In methanol31%
Multi-step reaction with 3 steps
1: ethanol / 9 h / Heating
2: 1.) NaH / 1.) THF, reflux, 30 min; 2.) THF, reflux, 6 h
3: H2 / 10percent Pd/C / ethanol / 24 h / 3102.9 Torr / Ambient temperature
View Scheme
4-(2-methoxyethenyl)phenol

4-(2-methoxyethenyl)phenol

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
With hydrogen In ethyl acetate at 50℃; under 30402 Torr; for 16h;10 g
methanol
67-56-1

methanol

4-(2-chloroethyl)phenol
28145-35-9

4-(2-chloroethyl)phenol

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
With sodium methylate at 50℃; for 7h; Reagent/catalyst;92%
1-(benzyloxy)-4-(2-methoxyethyl)benzene
98627-35-1

1-(benzyloxy)-4-(2-methoxyethyl)benzene

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
With palladium on activated charcoal; hydrogen In tetrahydrofuran at 20℃; under 3000.3 Torr; for 24h;82%
With hydrogen; palladium on activated charcoal In ethanol under 3102.9 Torr; for 24h; Ambient temperature;
With palladium 10% on activated carbon; hydrogen under 37503.8 Torr; for 3h;38.6 g
2-(4'-hydroxyphenyl)ethyl methyl carbonate
953422-33-8

2-(4'-hydroxyphenyl)ethyl methyl carbonate

carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
With Amberlyst 15 for 36h; Reflux;95%
p-hydroxyphenethyl alcohol
501-94-0

p-hydroxyphenethyl alcohol

sodium hydrogencarbonate
144-55-8

sodium hydrogencarbonate

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
In methanol65%
methanol
67-56-1

methanol

4-((3H-diazirin-3-yl)methyl)phenol

4-((3H-diazirin-3-yl)methyl)phenol

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
at 20℃; for 2h; Inert atmosphere; UV-irradiation;57%
4-(2-bromoethyl)phenol
14140-15-9

4-(2-bromoethyl)phenol

sodium methylate
124-41-4

sodium methylate

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
In methanol at 20℃; for 3h;79%
With methanol
p-hydroxyphenethyl alcohol
501-94-0

p-hydroxyphenethyl alcohol

poly(styrene-co-divinylbenzene)-supported methyl sulfonate, loading rate of SO3Me: ca. 4.0 mmol/g

poly(styrene-co-divinylbenzene)-supported methyl sulfonate, loading rate of SO3Me: ca. 4.0 mmol/g

A

2-(4-Methoxyphenyl)ethanol
702-23-8

2-(4-Methoxyphenyl)ethanol

B

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
With potassium carbonate In acetonitrile for 24h; Heating;A 82%
B 9%
L-tyrosine
60-18-4

L-tyrosine

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: ammonia; [bis(acetoxy)iodo]benzene / methanol / 2 h / 0 - 20 °C / Inert atmosphere
2: 2 h / 20 °C / Inert atmosphere; UV-irradiation
View Scheme
L-<15N>tyrosine
35424-81-8

L-<15N>tyrosine

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: ammonia; [bis(acetoxy)iodo]benzene; potassium hydroxide / methanol / 2 h / 0 °C
2: 2 h / 20 °C / Inert atmosphere; UV-irradiation
View Scheme
2-(4-benzyloxyphenyl)ethanol
61439-59-6

2-(4-benzyloxyphenyl)ethanol

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1.) NaH / 1.) THF, reflux, 30 min; 2.) THF, reflux, 6 h
2: H2 / 10percent Pd/C / ethanol / 24 h / 3102.9 Torr / Ambient temperature
View Scheme
Multi-step reaction with 2 steps
1: potassium hydroxide / dimethyl sulfoxide / 20 °C
2: palladium on activated charcoal; hydrogen / tetrahydrofuran / 24 h / 20 °C / 3000.3 Torr
View Scheme
phenol
108-95-2

phenol

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 50 percent / AlCl3 / various solvent(s) / 5 h / 70 °C
2: 90 percent / methanol / 24 h / Ambient temperature
3: 96 percent / H2 / 10percent Pd/C / ethanol / 4 h / 2327.2 Torr
View Scheme
Multi-step reaction with 3 steps
1: aluminum (III) chloride
2: methanol / pH 8
3: hydrogen / 3000.3 Torr / Heating
View Scheme
2-bromo-1-(4'-hydroxyphenyl)-1-ethanone
2491-38-5

2-bromo-1-(4'-hydroxyphenyl)-1-ethanone

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: methanol
2: H2; AcOH / Pd/C
View Scheme
4-Hydroxyacetophenone
99-93-4

4-Hydroxyacetophenone

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: CuBr2 / ethyl acetate
2: methanol
3: H2; AcOH / Pd/C
View Scheme
p-hydroxyphenacyl chloride
6305-04-0

p-hydroxyphenacyl chloride

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 90 percent / methanol / 24 h / Ambient temperature
2: 96 percent / H2 / 10percent Pd/C / ethanol / 4 h / 2327.2 Torr
View Scheme
Acetic acid 4-(2-methoxy-ethyl)-phenyl ester
82099-82-9

Acetic acid 4-(2-methoxy-ethyl)-phenyl ester

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
With sodium hydroxide In ethanol for 4h; Heating;
With sodium hydroxide
2-phenylethanol
60-12-8

2-phenylethanol

ZnCl2

ZnCl2

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
2: NaOH
3: H2O2, HCOOH
4: NaOH
View Scheme
Multi-step reaction with 6 steps
1: 207 g / pyridine / benzene / 5 h / 25 - 30 °C
2: 218 g / aluminium chloride / CH2Cl2 / 6 h / Ambient temperature
3: 71 g / sodium hydroxide / ethanol / 5 h / Heating
4: sodium hydroxide / dimethylsulfoxide / 4 h / 50 - 60 °C
5: 88 percent formic acid, cc. sulfuric acid, 35 percent hydrogen peroxide / acetic anhydride / 3 h / 40 - 50 °C
6: sodium hydroxide / ethanol / 4 h / Heating
View Scheme
1-<4-(1-hydroxyethyl)phenyl>ethanone
99215-51-7

1-<4-(1-hydroxyethyl)phenyl>ethanone

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: NaOH
2: H2O2, HCOOH
3: NaOH
View Scheme
Multi-step reaction with 3 steps
1: sodium hydroxide / dimethylsulfoxide / 4 h / 50 - 60 °C
2: 88 percent formic acid, cc. sulfuric acid, 35 percent hydrogen peroxide / acetic anhydride / 3 h / 40 - 50 °C
3: sodium hydroxide / ethanol / 4 h / Heating
View Scheme
4-methoxyethylacetophenone
93205-89-1

4-methoxyethylacetophenone

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: H2O2, HCOOH
2: NaOH
View Scheme
Multi-step reaction with 2 steps
1: 88 percent formic acid, cc. sulfuric acid, 35 percent hydrogen peroxide / acetic anhydride / 3 h / 40 - 50 °C
2: sodium hydroxide / ethanol / 4 h / Heating
View Scheme
4-chloro-phenol
106-48-9

4-chloro-phenol

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 80 °C
1.2: 1 h / 105 °C
2.1: magnesium; iodine / 2-methyltetrahydrofuran / 2 h / Reflux
3.1: sodium hydroxide / toluene; water / 2 h
3.2: 2 h
4.1: palladium 10% on activated carbon; hydrogen / 3 h / 37503.8 Torr
View Scheme
Multi-step reaction with 4 steps
1.1: sulfuric acid / toluene / 16 h / -10 - 0 °C
2.1: magnesium / tetrahydrofuran / 16 h / 65 - 72 °C / Inert atmosphere
2.2: 0 - 10 °C / Inert atmosphere
3.1: thionyl chloride; N,N-dimethyl-formamide / toluene / 2 h / 55 - 60 °C
4.1: sodium methylate / 7 h / 50 °C
View Scheme
para-nitrophenyl bromide
586-78-7

para-nitrophenyl bromide

magnesium

magnesium

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1.) Et3N, 2.) H2 / 1/2.) 5percent Pd/C / 1.) toluene, 120 deg C, 16 h, 2.) toluene, 85 deg C, 150 psi, 45 min
2: 1.) NaNO2, 50percent H2SO4, 2.) urea / 1.) H20, 5 deg C, 15 min, 2.) H2O, 100 - 105 deg C, 1 h
View Scheme
β-(4-acetylphenyl)ethyl acetate
73823-79-7

β-(4-acetylphenyl)ethyl acetate

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 71 g / sodium hydroxide / ethanol / 5 h / Heating
2: sodium hydroxide / dimethylsulfoxide / 4 h / 50 - 60 °C
3: 88 percent formic acid, cc. sulfuric acid, 35 percent hydrogen peroxide / acetic anhydride / 3 h / 40 - 50 °C
4: sodium hydroxide / ethanol / 4 h / Heating
View Scheme
acetic acid phenethyl ester
103-45-7

acetic acid phenethyl ester

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 218 g / aluminium chloride / CH2Cl2 / 6 h / Ambient temperature
2: 71 g / sodium hydroxide / ethanol / 5 h / Heating
3: sodium hydroxide / dimethylsulfoxide / 4 h / 50 - 60 °C
4: 88 percent formic acid, cc. sulfuric acid, 35 percent hydrogen peroxide / acetic anhydride / 3 h / 40 - 50 °C
5: sodium hydroxide / ethanol / 4 h / Heating
View Scheme
4-chlorophenyl benzyl ether
7700-27-8

4-chlorophenyl benzyl ether

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: magnesium; iodine / 2-methyltetrahydrofuran / 2 h / Reflux
2.1: sodium hydroxide / toluene; water / 2 h
2.2: 2 h
3.1: palladium 10% on activated carbon; hydrogen / 3 h / 37503.8 Torr
View Scheme
4-tert-butoxychlorobenzene
18995-35-2

4-tert-butoxychlorobenzene

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: magnesium / tetrahydrofuran / 16 h / 65 - 72 °C / Inert atmosphere
1.2: 0 - 10 °C / Inert atmosphere
2.1: thionyl chloride; N,N-dimethyl-formamide / toluene / 2 h / 55 - 60 °C
3.1: sodium methylate / 7 h / 50 °C
View Scheme
4-tert-butoxybromobenzene
60876-70-2

4-tert-butoxybromobenzene

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: magnesium / tetrahydrofuran / 6 h / 65 - 72 °C / Inert atmosphere
1.2: 0 - 10 °C / Inert atmosphere
2.1: thionyl chloride; N,N-dimethyl-formamide / toluene / 2 h / 55 - 60 °C
3.1: sodium methylate / 7 h / 50 °C
View Scheme
4-bromo-phenol
106-41-2

4-bromo-phenol

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: sulfuric acid / toluene / 16 h / -10 - 0 °C
2.1: magnesium / tetrahydrofuran / 6 h / 65 - 72 °C / Inert atmosphere
2.2: 0 - 10 °C / Inert atmosphere
3.1: thionyl chloride; N,N-dimethyl-formamide / toluene / 2 h / 55 - 60 °C
4.1: sodium methylate / 7 h / 50 °C
View Scheme
4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

4-[(4-chloro-2-pyrimidinyl)amino]benzonitrile
244768-32-9

4-[(4-chloro-2-pyrimidinyl)amino]benzonitrile

4-{4-[4-(2-methoxylethyl)phenoxy]pyrimidin-2-ylamino}benzonitrile
1448695-92-8

4-{4-[4-(2-methoxylethyl)phenoxy]pyrimidin-2-ylamino}benzonitrile

Conditions
ConditionsYield
Stage #1: 4-(2-methoxyethyl)phenol With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.166667h; Inert atmosphere;
Stage #2: 4-[(4-chloro-2-pyrimidinyl)amino]benzonitrile In N,N-dimethyl-formamide at 80℃; Inert atmosphere;
98.4%
succinic acid
110-15-6

succinic acid

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

isopropylamine
75-31-0

isopropylamine

epichlorohydrin
106-89-8

epichlorohydrin

metoprolol succinate

metoprolol succinate

Conditions
ConditionsYield
Stage #1: 4-(2-methoxyethyl)phenol; epichlorohydrin With sodium hydroxide In water at 30 - 40℃; for 5h;
Stage #2: isopropylamine In water at 20 - 30℃; for 5h;
Stage #3: succinic acid In acetone at 20 - 35℃; Temperature; Solvent;
97.8%
3-hydroxy-3-phenyl-2,3-dihydro-isoindol-1-one
6637-53-2, 144252-21-1, 144252-22-2

3-hydroxy-3-phenyl-2,3-dihydro-isoindol-1-one

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

3-(2-hydroxy-5-(2-methoxyethyl)phenyl)-3-phenylisoindolin-1-one

3-(2-hydroxy-5-(2-methoxyethyl)phenyl)-3-phenylisoindolin-1-one

Conditions
ConditionsYield
Stage #1: 3-hydroxy-3-phenyl-2,3-dihydro-isoindol-1-one With methanesulfonic acid In cyclohexane at 25℃; for 0.166667h; Betti Reaction;
Stage #2: 4-(2-methoxyethyl)phenol In cyclohexane at 80℃; for 16h; Betti Reaction;
97%
4-(4-chloro-6-methyl-pyrimidin-2-ylamino)-benzonitrile

4-(4-chloro-6-methyl-pyrimidin-2-ylamino)-benzonitrile

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

4-{6-methyl-4-[4-(2-methoxylethyl)phenoxy]pyrimidin-2-ylamino}benzonitrile
1448695-99-5

4-{6-methyl-4-[4-(2-methoxylethyl)phenoxy]pyrimidin-2-ylamino}benzonitrile

Conditions
ConditionsYield
Stage #1: 4-(2-methoxyethyl)phenol With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.166667h; Inert atmosphere;
Stage #2: 4-(4-chloro-6-methyl-pyrimidin-2-ylamino)-benzonitrile In N,N-dimethyl-formamide at 80℃; Inert atmosphere;
96.2%
4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

epichlorohydrin
106-89-8

epichlorohydrin

2-[4-(2'-methoxyethyl)phenoxymethyl]oxirane
56718-70-8

2-[4-(2'-methoxyethyl)phenoxymethyl]oxirane

Conditions
ConditionsYield
With sodium hydroxide at 85 - 90℃; pH=8; Temperature; pH-value; Flow reactor;95.2%
With sodium hydroxide at 90 - 115℃; under 1500.15 - 2250.23 Torr; pH=9; Flow reactor;95.2%
With sodium hydroxide In water at 40 - 45℃; for 3 - 5h;93%
4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

allyl bromide
106-95-6

allyl bromide

3-[4-(2-methoxyethyl)phenoxy]propylene
80448-05-1

3-[4-(2-methoxyethyl)phenoxy]propylene

Conditions
ConditionsYield
With potassium carbonate In acetone Reflux;87%
With potassium carbonate In acetone for 7h; Heating;85%
formic acid
64-18-6

formic acid

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

4-(2-Methoxyethyl)phenyl formate

4-(2-Methoxyethyl)phenyl formate

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); sodium acetate; acetic anhydride at 20℃; for 12h; Inert atmosphere;87%
4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

C14H19N2O2S(1+)*F6P(1-)

C14H19N2O2S(1+)*F6P(1-)

4-(2-methoxyethyl)phenyl-4-methylbenzenesulfonate

4-(2-methoxyethyl)phenyl-4-methylbenzenesulfonate

Conditions
ConditionsYield
With DBN In acetonitrile at 80℃; for 4h;84%
1,1,1,2,3,3-hexafluoro-2-(heptafluoropropoxy)-3-[(trifluorovinyl)oxy]propane
1644-11-7

1,1,1,2,3,3-hexafluoro-2-(heptafluoropropoxy)-3-[(trifluorovinyl)oxy]propane

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

1-(2-methoxy-ethyl)-4-[1,1,2-trifluoro-2-(1,1,2,3,3,3-hexafluoro-2-heptafluoropropyloxy-propoxy)-ethoxy]-benzene

1-(2-methoxy-ethyl)-4-[1,1,2-trifluoro-2-(1,1,2,3,3,3-hexafluoro-2-heptafluoropropyloxy-propoxy)-ethoxy]-benzene

Conditions
ConditionsYield
With potassium hydroxide Addition;78%
formic acid
64-18-6

formic acid

iodobenzene
591-50-4

iodobenzene

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

4-(2-methoxyethyl)phenyl benzoate

4-(2-methoxyethyl)phenyl benzoate

Conditions
ConditionsYield
With palladium diacetate; acetic anhydride; triethylamine; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene In toluene at 80℃; for 12h; Inert atmosphere;78%
(S)-epichlorohydrin
67843-74-7

(S)-epichlorohydrin

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

A

(2S)-2-{[4-(2-Methoxyethyl)phenoxy]methyl}oxirane
105780-38-9

(2S)-2-{[4-(2-Methoxyethyl)phenoxy]methyl}oxirane

B

(R)-2-{[4-(2-methoxyethyl)phenoxy]methyl}oxirane
133397-54-3

(R)-2-{[4-(2-methoxyethyl)phenoxy]methyl}oxirane

Conditions
ConditionsYield
With potassium carbonate In acetonitrile for 14h; Reflux; optical yield given as %ee;A n/a
B 75%
4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

(S,S,S)-triglycidyl isocyanurate

(S,S,S)-triglycidyl isocyanurate

(S)-5-((4-(2-methoxyethyl)phenoxy)methyl)oxazolidin-2-one
1333949-81-7

(S)-5-((4-(2-methoxyethyl)phenoxy)methyl)oxazolidin-2-one

Conditions
ConditionsYield
With potassium hydroxide In 4-methyl-2-pentanone at 110 - 115℃; for 2 - 3h; Large scale reaction;75%
(R)-(-)-epichlorohydrin
51594-55-9

(R)-(-)-epichlorohydrin

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

A

(2S)-2-{[4-(2-Methoxyethyl)phenoxy]methyl}oxirane
105780-38-9

(2S)-2-{[4-(2-Methoxyethyl)phenoxy]methyl}oxirane

B

(R)-2-{[4-(2-methoxyethyl)phenoxy]methyl}oxirane
133397-54-3

(R)-2-{[4-(2-methoxyethyl)phenoxy]methyl}oxirane

Conditions
ConditionsYield
With potassium carbonate In acetonitrile for 14h; Reflux; optical yield given as %ee;A 73%
B n/a
4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

(4S)-N-tert-butoxycarbonyl-4-[[(4'-methylbenzenesulfonyl)oxy]methyl]-2,2-dimethyl-1,3-oxazolidine
140645-28-9

(4S)-N-tert-butoxycarbonyl-4-[[(4'-methylbenzenesulfonyl)oxy]methyl]-2,2-dimethyl-1,3-oxazolidine

4(R)-4-((4-(2-methoxyethyl)phenoxy)methyl)-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester
935547-68-5

4(R)-4-((4-(2-methoxyethyl)phenoxy)methyl)-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Stage #1: 4-(2-methoxyethyl)phenol With sodium hydride In N,N-dimethyl-formamide at 20℃;
Stage #2: (4S)-N-tert-butoxycarbonyl-4-[[(4'-methylbenzenesulfonyl)oxy]methyl]-2,2-dimethyl-1,3-oxazolidine In N,N-dimethyl-formamide at 40℃; for 1h;
71%
With sodium hydride In N,N-dimethyl-formamide at 60 - 80℃;
Stage #1: 4-(2-methoxyethyl)phenol With sodium hydride In N,N-dimethyl-formamide at 20℃; for 0.166667h;
Stage #2: (4S)-N-tert-butoxycarbonyl-4-[[(4'-methylbenzenesulfonyl)oxy]methyl]-2,2-dimethyl-1,3-oxazolidine In N,N-dimethyl-formamide at 60 - 80℃; for 2h; Further stages.;
1-(6-chloro-5-nitro-pyrimidin-4-yl)-piperidine-4-carboxylic acid ethyl ester
733747-96-1

1-(6-chloro-5-nitro-pyrimidin-4-yl)-piperidine-4-carboxylic acid ethyl ester

4-(2-methoxyethyl)phenol
56718-71-9

4-(2-methoxyethyl)phenol

1-{6-[4-(2-methoxyethyl)-phenoxy]-5-nitropyrimidin-4-yl}-piperidine-4-carboxylic acid ethyl ester
733748-32-8

1-{6-[4-(2-methoxyethyl)-phenoxy]-5-nitropyrimidin-4-yl}-piperidine-4-carboxylic acid ethyl ester

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 90℃; for 15h;71%
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