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Hangzhou Lingrui Chemical Co.,Ltd.

Molecular Formula C5H3Br2N Molar Mass 236.89 Density 2.0383 (rough estimate) Melting Point 92-95 °C (lit.) Boling Point 235 °C / 772mmHg Flash Point 62℃ Water So

Hot sale 624-28-2 Best price 2,5-Dibromopyridine exporter

Cas:624-28-2

Min.Order:1 Metric Ton

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Type:Other

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Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and

2,5-Dibromopyridine

Cas:624-28-2

Min.Order:0 Metric Ton

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Shanghai Surseechem Co.,Ltd.

ProName: 2,5-Dibromopyridine CasNo: 624-28-2 Appearance: Off-white crystals Application: Important fine chemical material DeliveryTime: In stock PackAge: 25kg per drum Port: Shanghai ProductionCapacity: 5000 Kilogram/

lower price 2,5-Dibromopyridine

Cas:624-28-2

Min.Order:1 Kilogram

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Hangzhou Dingyan Chem Co., Ltd

high purity, manufacturer Application:Intermediate

2,5-Di Bromo Pyridine

Cas:624-28-2

Min.Order:0

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2,5-Dibromopyridine supplier in China

Cas:624-28-2

Min.Order:1 Metric Ton

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White powder Storage:Cool dry place Package:1kg/foill bag;25kg/drum Application:pharmaceut

2,5-Dibromopyridine Cas 624-28-2

Cas:624-28-2

Min.Order:1 Kilogram

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Henan Allgreen Chemical Co.,Ltd

T he company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality service Appearance:W

2,5-Dibromopyridine

Cas:624-28-2

Min.Order:1 Kilogram

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2,5-dibromopyridine

Cas:624-28-2

Min.Order:1

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Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% 624-28-2 2,5-Dibromopyridine Manufacturer

Cas:624-28-2

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for the fine c

2,5-Dibromopyridine 624-28-2 /manufacturer/low price/high quality/in stock

Cas:624-28-2

Min.Order:1 Kilogram

FOB Price: $10.0 / 11.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2,5-Dibromopyridine

Cas:624-28-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

Hebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car

2,5-dibromopyridine

Cas:624-28-2

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

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Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com/pro01en/id/1973.html Product Name 2,5-Dibromopyridine CAS No. 624-28-2

2,5-Dibromopyridine

Cas:624-28-2

Min.Order:1 Gram

FOB Price: $2.0

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

2,5-Dibromopyridine Basic information Product Name: 2,5-Dibromopyridine Synonyms: PYRIDINE, 2,5-DIBROMO-;2,5-DIBROMOPYRIDINE;Dibromopyridine;2,5-Dibromopyridine, 97+%;2,5-dibromopyri

best offer 2,5-Dibromopyridine

Cas:624-28-2

Min.Order:1 Metric Ton

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

2, 5-Dibromopyridine CAS 624-28-2

Cas:624-28-2

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

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Henan Sinotech Import&Export Corporation

Name: 2,5-Dibromopyridine CAS:624-28-2 MF: C5H3Br2N Appearance:White Powder Storage:Store in cool and dry place, away from sun light. Package:25KG Application:APIs Transportation:By sea or by air Port:Qingdao Port

2,5-Dibromopyridine CAS: 624-28-2

Cas:624-28-2

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

UPS Standard CAS 624-28-2 with fast shipping

Cas:624-28-2

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

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Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

2,5-DibromopyridineCAS:624-28-2

Cas:624-28-2

Min.Order:1 Kilogram

FOB Price: $20.0 / 30.0

Type:Trading Company

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry plac

High Quality 99% 2,5-Dibromopyridine CAS No 624-28-2

Cas:624-28-2

Min.Order:100 Gram

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2,5-Dibromopyridine 624-28-2

Cas:624-28-2

Min.Order:1 Kilogram

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Pharmaceutical Intermediate, 2,5-Dibromopyridine CAS:624-28-2

Cas:624-28-2

Min.Order:1 Kilogram

FOB Price: $41.4 / 48.6

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

2,5-Dibromopyridine CAS: 624-28-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic interm

2,5-Dibromopyridine CAS: 624-28-2

Cas:624-28-2

Min.Order:1 Gram

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2,5-Dibromopyridine

Cas:624-28-2

Min.Order:1 Kilogram

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Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram

2,5-Dibromopyridine CAS NO.624-28-2

Cas:624-28-2

Min.Order:10 Gram

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

2,5-Dibromopyridine

Cas:624-28-2

Min.Order:10 Kilogram

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:624-28-2

Cas:624-28-2

Min.Order:0

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2,5-Dibromopyridine

Cas:624-28-2

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Triumph International Development Limilted

Appearance:white or yellowish white flaky crystal Storage:Keep the sun from direct sunlight ;prevention against high temperature Package:As customer request Application:Used for research and industrial manufacture. Transportatio

2,5-Dibromopyridine

Cas:624-28-2

Min.Order:100 Metric Ton

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Type:Lab/Research institutions

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2,5-Dibromopyridine

Cas:624-28-2

Min.Order:0 Metric Ton

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

2,5-DIBROMOPYRIDINE

Cas:624-28-2

Min.Order:1 Gram

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Synthetic route

5-bromopyridin-2-ol
13466-38-1

5-bromopyridin-2-ol

2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

Conditions
ConditionsYield
With triphenylborane; phosphorus tribromide In 1,2-dichloro-ethane for 10h; Reagent/catalyst; Solvent; Inert atmosphere; Reflux;88.7%
With phosphorus(V) oxybromide In acetonitrile at 80℃; for 21h; Reagent/catalyst; Temperature;470 mg
5-bromo-2-pyridylamine
1072-97-5

5-bromo-2-pyridylamine

2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

Conditions
ConditionsYield
Stage #1: 5-bromo-2-pyridylamine With hydrogen bromide; bromine In water at 0 - 20℃; for 0.166667h;
Stage #2: With sodium nitrite In water at 0 - 5℃; for 0.5h;
87%
With tert.-butylnitrite; trimethylbenzylammonium bromide; 1,2-dibromomethane at 20℃;83%
With tert.-butylnitrite; trimethylbenzylammonium bromide In 1,2-dibromomethane at 20℃;83%
2-bromo-pyridine
109-04-6

2-bromo-pyridine

A

2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

B

2,3,5-tribromopyridine
75806-85-8

2,3,5-tribromopyridine

Conditions
ConditionsYield
With bromine at 300℃; Leiten ueber mit Eisen(II)-bromid impraegnierten Bimsstein;
3-Bromopyridine
626-55-1

3-Bromopyridine

A

2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

B

2,3,6-tribromopyridine
2402-92-8

2,3,6-tribromopyridine

Conditions
ConditionsYield
With bromine at 500℃; Leiten ueber Bimsstein;
1-methyl-2-pyridone
694-85-9

1-methyl-2-pyridone

phosphorus pentabromide
7789-69-7

phosphorus pentabromide

2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

Conditions
ConditionsYield
at 140 - 150℃;
diazotized 5-bromo-2-amino-pyridine

diazotized 5-bromo-2-amino-pyridine

2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

Conditions
ConditionsYield
With hydrogen bromide
N-methyl-α-pyridone

N-methyl-α-pyridone

A

2-bromo-pyridine
109-04-6

2-bromo-pyridine

B

2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

Conditions
ConditionsYield
With phosphorus pentabromide; phosphorus(V) oxybromide at 120 - 130℃;
With phosphorus pentabromide at 140 - 150℃;
3-Bromopyridine
626-55-1

3-Bromopyridine

bromine
7726-95-6

bromine

pumice stone

pumice stone

A

2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

B

2,3,6-tribromopyridine
2402-92-8

2,3,6-tribromopyridine

Conditions
ConditionsYield
at 500℃;
2-bromo-pyridine
109-04-6

2-bromo-pyridine

bromine
7726-95-6

bromine

iron (II)-bromide

iron (II)-bromide

A

2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

B

2,3,5-tribromopyridine
75806-85-8

2,3,5-tribromopyridine

Conditions
ConditionsYield
at 300℃;
2-aminopyridine
504-29-0

2-aminopyridine

2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: ethanol; bromine / <20
2: bromine; aqueous hydrobromic acid / anschliessend Behandeln mit wss. Natriumnitrit-Loesung unterhalb von 0grad
View Scheme
Multi-step reaction with 2 steps
1: N-Bromosuccinimide; ammonium acetate / acetonitrile / 0.08 h / 20 °C
2: tert.-butylnitrite; trimethylbenzylammonium bromide; 1,2-dibromomethane / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: N-Bromosuccinimide; ammonium acetate / acetonitrile / 0.08 h / 20 °C
2: tert.-butylnitrite; trimethylbenzylammonium bromide / 1,2-dibromomethane / 20 °C
View Scheme
6-hydroxy-4-methoxymethyl-β-carboline-3-carboxylic acid ethyl ester
96136-88-8

6-hydroxy-4-methoxymethyl-β-carboline-3-carboxylic acid ethyl ester

A

2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

B

6-(5-bromo-2-pyridyloxy)-4-methoxymethyl-β-carboline-3-carboxylic acid ethyl ester
111110-50-0

6-(5-bromo-2-pyridyloxy)-4-methoxymethyl-β-carboline-3-carboxylic acid ethyl ester

(2-hydroxyethyl)(methyl)amine
109-83-1

(2-hydroxyethyl)(methyl)amine

2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

2-[(5-bromopyridin-2-yl)methylamino]ethanol
149806-47-3

2-[(5-bromopyridin-2-yl)methylamino]ethanol

Conditions
ConditionsYield
at 150℃; for 18h;100%
potassium fluoride on basic alumina for 0.25h; microwave irradiation;86%
2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

Na(1+)*((CH3)3SiCC)4Al(1-)

Na(1+)*((CH3)3SiCC)4Al(1-)

3-bromo-6-(trimethylsilylethynyl)pyridine
111770-80-0

3-bromo-6-(trimethylsilylethynyl)pyridine

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride for 12h; Heating;100%
2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

dimethyl(hept-1-yn-1-yl)aluminum

dimethyl(hept-1-yn-1-yl)aluminum

2,5-di-hept-1-ynyl-pyridine

2,5-di-hept-1-ynyl-pyridine

Conditions
ConditionsYield
With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; 1,1'-bis-(diphenylphosphino)ferrocene In 1,2-dimethoxyethane; n-heptane at 85℃; for 1h;100%
2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

[1-(5-bromo-pyridin-2-yl)-pyrrolidin-3-yl]-dimethyl-amine
690264-82-5

[1-(5-bromo-pyridin-2-yl)-pyrrolidin-3-yl]-dimethyl-amine

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 250℃; for 0.5h; Microwave irradiation;100%
With toluene-4-sulfonic acid In water at 140℃; for 14h;96%
With toluene-4-sulfonic acid at 130℃;
2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

3,4-dichlorophenol
95-77-2

3,4-dichlorophenol

5-bromo-2-(3,4-dichloro-phenoxy)-pyridine
99902-96-2

5-bromo-2-(3,4-dichloro-phenoxy)-pyridine

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 90℃; for 18h;100%
2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

(tert-butyldimethylsilyl)acetylene
86318-61-8

(tert-butyldimethylsilyl)acetylene

2-(tert-butyldimethylsilylethynyl)-5-bromopyridine
866929-82-0

2-(tert-butyldimethylsilylethynyl)-5-bromopyridine

Conditions
ConditionsYield
With triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide In tetrahydrofuran at -7 - 20℃; for 4h;100%
With triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; N,N`-dimethylethylenediamine In tetrahydrofuran at -7 - 20℃; for 4h;100%
With triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide In tetrahydrofuran at -7 - 20℃; for 4h;100%
2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

cyclopropylzinc chloride
203861-73-8

cyclopropylzinc chloride

3-bromo-6-(cyclopropyl)pyridine
579475-29-9

3-bromo-6-(cyclopropyl)pyridine

Conditions
ConditionsYield
tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 70℃; for 3h;100%
tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 70℃; for 1.5h;
2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

(3,3-dimethylbut-1-yn-1-yl)dimethylsilane
87290-98-0

(3,3-dimethylbut-1-yn-1-yl)dimethylsilane

2-(tert-butyldimethylsilylethynyl)-5-bromopyridine
866929-82-0

2-(tert-butyldimethylsilylethynyl)-5-bromopyridine

Conditions
ConditionsYield
With triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide In tetrahydrofuran at -7 - 20℃; for 4h;100%
2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

N,N-dimethyl acetamide
127-19-5

N,N-dimethyl acetamide

1-(5-bromopyridin-2-yl)ethanone
214701-49-2

1-(5-bromopyridin-2-yl)ethanone

Conditions
ConditionsYield
With n-butyllithium In hexane; toluene at -40 - 20℃; for 2h; Inert atmosphere;100%
Stage #1: 2,5-dibromopyridine With n-butyllithium In hexane; toluene at -40℃; for 0.666667h;
Stage #2: N,N-dimethyl acetamide In hexane; toluene at 20℃; for 1h; Further stages.;
83%
Stage #1: 2,5-dibromopyridine With n-butyllithium In toluene Inert atmosphere;
Stage #2: N,N-dimethyl acetamide In toluene Inert atmosphere;
83%
2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

methylamine
74-89-5

methylamine

5-bromo-N-methylpyridin-2-amine
84539-30-0

5-bromo-N-methylpyridin-2-amine

Conditions
ConditionsYield
In ethanol at 80℃; for 24h;100%
In ethanol at 80℃; for 72h;1.20 g
In methanol Autoclave; Large scale;
2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

1-tert-butoxycarbonyl-4-cyanopiperidine
91419-52-2

1-tert-butoxycarbonyl-4-cyanopiperidine

tert-butyl 4-(5-bromopyridin-2-yl)-4-cyanopiperidine-1-carboxylate
1196973-42-8

tert-butyl 4-(5-bromopyridin-2-yl)-4-cyanopiperidine-1-carboxylate

Conditions
ConditionsYield
With lithium hexamethyldisilazane In toluene at 20℃; for 16h; Inert atmosphere;100%
2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

3-fluorophenol
372-20-3

3-fluorophenol

5-bromo-2-(3-fluorophenoxy)pyridine
936343-48-5

5-bromo-2-(3-fluorophenoxy)pyridine

Conditions
ConditionsYield
Stage #1: 3-fluorophenol With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.166667h;
Stage #2: 2,5-dibromopyridine In N,N-dimethyl-formamide at 0 - 110℃; for 7.75h;
100%
With potassium carbonate In N,N-dimethyl-formamide for 12h; Reflux; Large scale;85%
morpholine
110-91-8

morpholine

2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

5-bromo-2-(4-morpholinyl)pyridine
200064-11-5

5-bromo-2-(4-morpholinyl)pyridine

Conditions
ConditionsYield
With 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; sodium t-butanolate; tris(dibenzylideneacetone)dipalladium (0) In toluene at 100℃; for 3h;99%
at 120℃; for 1.66667h; microwave;99.7%
With potassium fluoride on basic alumina; dichlorobis(tri-O-tolylphosphine)palladium at 90 - 100℃; for 5h;92%
2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

benzyl alcohol
100-51-6

benzyl alcohol

2-(benzyloxy)-5-bromopyridine
83664-33-9

2-(benzyloxy)-5-bromopyridine

Conditions
ConditionsYield
With dibenzo-18-crown-6 In toluene for 3h; Heating;99%
Stage #1: benzyl alcohol With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 0.5h; Cooling with ice;
Stage #2: 2,5-dibromopyridine In N,N-dimethyl-formamide; mineral oil for 5h;
Stage #3: With acetic acid In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.5h;
99%
With potassium hydroxide; dibenzo-18-crown-6 In toluene for 1.5h; Heating / reflux;92%
1-methyl-piperazine
109-01-3

1-methyl-piperazine

2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

1-N-(5-bromopyridin-2-yl)-4-methylpiperazine
364794-58-1

1-N-(5-bromopyridin-2-yl)-4-methylpiperazine

Conditions
ConditionsYield
With 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; sodium t-butanolate; tris(dibenzylideneacetone)dipalladium (0) In toluene at 100℃; for 3h;99%
In butan-1-ol for 96h; Reflux;70%
With sodium hydrogencarbonate67.1%
2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

1-t-Butoxycarbonylpiperazine
57260-71-6

1-t-Butoxycarbonylpiperazine

5-Bromo-2-(4-tert-butoxycarbonylpiperazin-1-yl)pyridine
153747-97-8

5-Bromo-2-(4-tert-butoxycarbonylpiperazin-1-yl)pyridine

Conditions
ConditionsYield
With 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; sodium t-butanolate; tris(dibenzylideneacetone)dipalladium (0) In toluene at 100℃; for 3h;99%
With tris-(dibenzylideneacetone)dipalladium(0); 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; sodium t-butanolate In toluene at 80℃; for 4h; Sealed tube; Inert atmosphere;82%
With pyridine at 125℃; for 12h;39.5%
With potassium carbonate In dimethyl sulfoxide at 150℃; for 21h;
2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

methanol
67-56-1

methanol

carbon monoxide
201230-82-2

carbon monoxide

dimethyl 2,5-pyridine dicarboxylate
881-86-7

dimethyl 2,5-pyridine dicarboxylate

Conditions
ConditionsYield
With dichloro[2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]palladium(II); triethylamine at 100℃; under 2585.74 Torr; for 1h;99%
2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

bromobenzene
108-86-1

bromobenzene

5-bromo-2-phenylpyridine
27012-25-5

5-bromo-2-phenylpyridine

Conditions
ConditionsYield
Stage #1: bromobenzene With n-butyllithium In tetrahydrofuran; hexane; cyclohexane at -78℃; for 0.5h; Inert atmosphere;
Stage #2: With zinc(II) chloride In tetrahydrofuran; hexane; cyclohexane at -78 - 20℃; for 2.6h; Inert atmosphere;
Stage #3: 2,5-dibromopyridine With tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran; hexane; cyclohexane for 16h; Negishi coupling reaction; Inert atmosphere; Reflux;
99%
2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

trimethylsilylacetylene
1066-54-2

trimethylsilylacetylene

3-bromo-6-(trimethylsilylethynyl)pyridine
111770-80-0

3-bromo-6-(trimethylsilylethynyl)pyridine

Conditions
ConditionsYield
With triethylamine; copper(l) iodide; tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 17 - 30℃; for 0.5h; Sonogashira Coupling;98%
With copper(l) iodide; palladium dichloride In triethylamine at 30℃; for 2.17h; Inert atmosphere;97%
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); triethylamine In tetrahydrofuran at 20℃; Sonogashira cross-coupling; Inert atmosphere;92%
2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

ethylenediamine
107-15-3

ethylenediamine

N1-(5-bromopyridin-2-yl)ethane-1,2-diamine
199522-66-2

N1-(5-bromopyridin-2-yl)ethane-1,2-diamine

Conditions
ConditionsYield
at 100℃; for 15h;98%
at 100℃; for 15h;98%
With pyridine for 18h; Heating;71%
at 100℃; for 16h;
2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

methanol
67-56-1

methanol

2-methoxy-5-bromopyridine
13472-85-0

2-methoxy-5-bromopyridine

Conditions
ConditionsYield
With sodium hydroxide for 5h; Reflux;98%
With sodium In N,N-dimethyl-formamide at 80℃; for 1h; Substitution;95%
With potassium tert-butylate In DMF (N,N-dimethyl-formamide) at 20℃; for 18h;
With sodium methylate In methanol for 0.5h; Reflux;
2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

2,5-bis(2-ethylhexyloxy)benzene-1,4-diboronic acid
191917-63-2

2,5-bis(2-ethylhexyloxy)benzene-1,4-diboronic acid

poly{2,5-pyridilene-co-1,4-[2,5-bis-(2-ethylhexyloxy)]phenylene}, AB copolymer, Mw: 12000, Mn: 7400, polydispersity: 2.46; monomer(s): 2,5-dibromopyridine, 1,4-[2,5-bis(2-ethylhexyloxy)]diboronic acid

poly{2,5-pyridilene-co-1,4-[2,5-bis-(2-ethylhexyloxy)]phenylene}, AB copolymer, Mw: 12000, Mn: 7400, polydispersity: 2.46; monomer(s): 2,5-dibromopyridine, 1,4-[2,5-bis(2-ethylhexyloxy)]diboronic acid

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In tetrahydrofuran; water at 70℃; for 60h; Heating;98%
2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

Dimethyldisulphide
624-92-0

Dimethyldisulphide

2-bromo-5-methylthiopyridine
134872-23-4

2-bromo-5-methylthiopyridine

Conditions
ConditionsYield
Stage #1: 2,5-dibromopyridine With n-butyllithium In diethyl ether at -78℃;
Stage #2: Dimethyldisulphide In diethyl ether
98%
Stage #1: 2,5-dibromopyridine With n-butyllithium In diethyl ether; hexane at -78℃; for 1h;
Stage #2: Dimethyldisulphide In diethyl ether; hexane at -78 - 0℃; for 2h; Further stages.;
94%
With hydrogenchloride; n-butyllithium In hexane94%
piperidine
110-89-4

piperidine

2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

5'-bromo-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl
24255-95-6

5'-bromo-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl

Conditions
ConditionsYield
With 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene; sodium t-butanolate; tris(dibenzylideneacetone)dipalladium (0) In toluene at 100℃; for 3h;98%
at 80℃; for 96h;94%
With copper(l) iodide; potassium carbonate at 80℃; for 2h;92%
With copper(l) iodide; potassium carbonate; L-proline In dimethyl sulfoxide at 80℃; for 40h; Inert atmosphere;28%
With copper(l) iodide; bis(benzonitrile)palladium(II) dichloride Sonogashira coupling;
4-methylpiperidin
626-58-4

4-methylpiperidin

2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

1-N-(5-bromopyridin-2-yl)-4-methylpiperidine

1-N-(5-bromopyridin-2-yl)-4-methylpiperidine

Conditions
ConditionsYield
With 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene; sodium t-butanolate; tris(dibenzylideneacetone)dipalladium (0) In toluene at 100℃; for 3h;98%
pyrrolidine
123-75-1

pyrrolidine

2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

5-bromo-2-(pyrrolidin-1-yl)pyridine
210963-93-2

5-bromo-2-(pyrrolidin-1-yl)pyridine

Conditions
ConditionsYield
In butan-1-ol at 75℃; for 16h; sealed tube;98%
at 110℃; for 1.5h;55%
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide Sonogashira coupling;
2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

ethanolamine
141-43-5

ethanolamine

2-[(5-bromopyridin-2-yl)amino]ethanol

2-[(5-bromopyridin-2-yl)amino]ethanol

Conditions
ConditionsYield
for 3h; Reflux;98%
for 3h; Reflux;98%
at 220 - 250℃; for 0.5h; Microwave irradiation;95%
potassium fluoride on basic alumina for 0.25h; microwave irradiation;85%
2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

tert-butyl 4-(hydroxymethyl)piperidin-1-carboxylate
123855-51-6

tert-butyl 4-(hydroxymethyl)piperidin-1-carboxylate

tert-butyl 4-((5-bromopyridin-2-yloxy)methyl)piperidine-1-carboxylate
1010114-48-3

tert-butyl 4-((5-bromopyridin-2-yloxy)methyl)piperidine-1-carboxylate

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 20℃; for 3h; Temperature; Concentration;98%
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 80℃; for 5h;87%
Stage #1: tert-butyl 4-(hydroxymethyl)piperidin-1-carboxylate With sodium hydride In dimethyl sulfoxide; mineral oil at 20 - 50℃; for 1.5h;
Stage #2: 2,5-dibromopyridine In dimethyl sulfoxide; mineral oil at 20℃;
84%
With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 3h;78%
2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

2-bromo-9H-carbazole
3652-90-2

2-bromo-9H-carbazole

2-bromo-9-(5-bromopyridin-2-yl)-9H-carbazole

2-bromo-9-(5-bromopyridin-2-yl)-9H-carbazole

Conditions
ConditionsYield
With 1-methyl-1H-imidazole; copper(l) chloride; lithium tert-butoxide In toluene at 130℃; for 5h; Inert atmosphere;98%
With 1-methyl-1H-imidazole; copper(l) chloride; lithium tert-butoxide In toluene at 130℃; for 5h; Ullmann Condensation; chemoselective reaction;80%
2,5-dibromopyridine
624-28-2

2,5-dibromopyridine

hex-1-yne
693-02-7

hex-1-yne

2,5-di-1-hexynylpyridine

2,5-di-1-hexynylpyridine

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 50℃; for 72h; Sonogashira coupling;97%
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