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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

6-Methoxy-2-(4-methoxyphenyl)benzobithiophene Manufacturer/High quality/Best price/In stock

Cas:63675-74-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 6-Methoxy-2-(4-Methoxyphenyl)Benzobithiophene supplier in China

Cas:63675-74-1

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:white powder Storage:Sealed, dry, microtherm , avoid light and smell Package:According to the demand of customer Application:Pharmaceutical intermediates Transportation:by air or by sea Port:shanghai

6-Methoxy-2-(4-methoxy?phenyl)benzothiophene

Cas:63675-74-1

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 6-methoxy-2-(4-methoxyphenyl)benzo[b]thiophene

Cas:63675-74-1

Min.Order:1

Negotiable

Type:Other

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

6-Methoxy-2-(4-methoxyphenyl)-benzo[b]thiophene

Cas:63675-74-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hubei DiBo chemical co., LTD

Name:6-Methoxy-2-(4-methoxyphenyl)benzobithiophene CAS NO: 63675-74-1 Grade:Medical scientific research and export Molecular formula: C16H14O2S Molecular weight:270.3462 Product Quality 12 years of chemical raw materials Mature operation

6-Methoxy-2-(4-methoxyphenyl)benzobithiophene/ CAS: 63675-74-1 /raw material/ high-quality

Cas:63675-74-1

Min.Order:25 Kilogram

FOB Price: $2.0 / 3.0

Type:Other

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Henan Tianfu Chemical Co., Ltd.

6-Methoxy-2-(4-methoxyphenyl)benzobithiophene Basic information Product Name: 6-Methoxy-2-(4-methoxyphenyl)benzobithiophene Synonyms: 4-(6-METHOXY-1-BENZOTHIOPHEN-2-YL)PHENYL METHYL ETHE

6-Methoxy-2-(4-methoxyphenyl)benzobithiophene

Cas:63675-74-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

2-(4-Methoxy phenyl)-6-methoxy benzo[b]thiophene

Cas:63675-74-1

Min.Order:1 Kilogram

FOB Price: $100.0 / 150.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 63675-74-1 with fast shipping

Cas:63675-74-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powd

6-Methoxy-2-(4-methoxyphenyl)benzobithiophene

Cas:63675-74-1

Min.Order:1 Kilogram

FOB Price: $50.0 / 100.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Product Name: 6-Methoxy-2-(4-methoxyphenyl)benzobithiophene Appearance: White crystal powder M.F.: C16H14O2S M.W.: 270.35 CAS NO.: 63675-74-1 EINECS NO.: 264-408-2 Appearance:White powder Storage:RT. Package:drum Application: Pharmaceutical

6-Methoxy-2-(4-methoxyphenyl)benzobithiophene

Cas:63675-74-1

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Hubei Langyou International Trading Co., Ltd

C16H14O2S 6-Methoxy-2-(4-methoxyphenyl)benzobithiophene 63675-74-1 1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearan

C16H14O2S 6-Methoxy-2-(4-methoxyphenyl)benzobithiophene 63675-74-1

Cas:63675-74-1

Min.Order:10 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzo[b]thiophene,6-methoxy-2-(4-methoxyphenyl)- 63675-74-1

Cas:63675-74-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hangzhou Maytime Bio-Tech Co.,Ltd.

Package:25kgs/fiber drum Application:Raloxifene intermediate Port:any port in China

Raloxifene intermediate cas:63675-74-1

Cas:63675-74-1

Min.Order:1 Kilogram

Negotiable

Type:Other

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present,

6-Methoxy-2-(4-methoxyphenyl)benzobithiophene

Cas:63675-74-1

Min.Order:1 Kilogram

FOB Price: $800.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

6-Methoxy-2-(4-methoxyphenyl)benzobithiophene CAS:63675-74-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in

6-Methoxy-2-(4-methoxyphenyl)benzobithiophene CAS:63675-74-1

Cas:63675-74-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Benzo[b]thiophene,6-methoxy-2-(4-methoxyphenyl)-

Cas:63675-74-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:63675-74-1

Cas:63675-74-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

6-Methoxy-2-(4-methoxyphenyl) benzo[b]thiophene

Cas:63675-74-1

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

6-Methoxy-2-(4-methoxyphenyl)benzobithiophene

Cas:63675-74-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

6-Methoxy-2-(4-methoxy?phenyl)benzothiophene CAS NO.63675-74-1

Cas:63675-74-1

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

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HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:10g/bag,or as your request Application:For medicine , pesticide intermediates Tran

6-Methoxy-2-(4-methoxyphenyl)benzobithiophene

Cas:63675-74-1

Min.Order:1 Gram

Negotiable

Type:Trading Company

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

6-Methoxy-2-(4-methoxyphenyl)benzobithiophene Manufacturer/High quality/Best price/In stock

Cas:63675-74-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Siwei Development Group Ltd.

Product name: 6-Methoxy-2-(4-Methoxyphenyl)Benzobithiophene CAS No.:63675-74-1 Molecule Formula:C16H14O2S Molecule Weight:270.34 Purity: 98% Package: 25kg/drum Description:White powder Manufacture Standards:Enterprise Standard TE

High Quality 6-Methoxy-2-(4-Methoxyphenyl)Benzobithiophene in stock

Cas:63675-74-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Best Price6-Methoxy-2-(4-methoxyphenyl)benzobithiophene

Cas:63675-74-1

Min.Order:0

Negotiable

Type:Trading Company

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Hangzhou Think Chemical Co. Ltd

HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the marketing & distribution, thinkchem specializes in exp

6-Methoxy-2-(4-Methoxyphenyl)Benzo[b]Thiophene CAS:63675-74-1]

Cas:63675-74-1

Min.Order:0 Metric Ton

Negotiable

Type:Other

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

C16H14O2S 6-Methoxy-2-(4-methoxyphenyl)benzobithiophene 63675-74-1

Cas:63675-74-1

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

6-Methoxy-2-(4-methoxyphenyl)benzobithiophene

Cas:63675-74-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

6-Methoxy-2-(4-methoxyphenyl)benzobithiophene

Cas:63675-74-1

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

C16H14O2S 6-Methoxy-2-(4-methoxyphenyl)benzobithiophene 63675-74-1

Cas:63675-74-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Synthetic route

(5-methoxy-2-((4-methoxyphenyl)ethynyl)phenyl)(methyl)-sulfane
1163701-10-7

(5-methoxy-2-((4-methoxyphenyl)ethynyl)phenyl)(methyl)-sulfane

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

Conditions
ConditionsYield
With trifluoroacetic acid; silver(l) oxide at 25℃; for 1.5h; Schlenk technique;89%
6-methoxy-benzo[b]thiophene
90560-10-4

6-methoxy-benzo[b]thiophene

para-iodoanisole
696-62-8

para-iodoanisole

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

Conditions
ConditionsYield
With dichloro(2,2'-bipyridine)nickel(II); lithium hexamethyldisilazane In 2-methyltetrahydrofuran at 120℃; for 16h; Schlenk technique; Sealed tube; Inert atmosphere; Glovebox; regiospecific reaction;85%
With palladium diacetate; silver trifluoroacetate; trifluoroacetic acid In water at 20℃; for 48h; Inert atmosphere;60%
para-iodoanisole
696-62-8

para-iodoanisole

6-methoxy-benzo[b]thiophen-2-yl boronic acid
182133-35-3

6-methoxy-benzo[b]thiophen-2-yl boronic acid

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In water at 110℃; for 12h; Suzuki coupling; Ionic liquid; Inert atmosphere;81%
With sodium carbonate; tetrakis(triphenylphosphine)palladium (0) In toluene1.25 g (96%)
6-methoxy-2-iodobenzo[b]thiophene
183133-89-3

6-methoxy-2-iodobenzo[b]thiophene

4-methoxyphenylboronic acid
5720-07-0

4-methoxyphenylboronic acid

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

Conditions
ConditionsYield
80%
α-(3-methoxyphenyl-thio)-4-methoxyacetophenone
63675-73-0

α-(3-methoxyphenyl-thio)-4-methoxyacetophenone

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

Conditions
ConditionsYield
Stage #1: α-(3-methoxyphenyl-thio)-4-methoxyacetophenone In toluene under 760.051 Torr; for 2h; Reflux; Inert atmosphere; Dean-Stark; Large scale;
Stage #2: With methanesulfonic acid In toluene at 90℃; for 4h; Inert atmosphere; Large scale;
Stage #3: In n-heptane; toluene at 80 - 90℃; for 4h; Reagent/catalyst; Solvent; Temperature; Inert atmosphere; Large scale;
79.6%
With PPA at 85 - 95℃; for 1.25h;
With polyphosphoric acid at 90℃; for 1h; Inert atmosphere;
With PPA
4-methoxyphenylacetylen
768-60-5

4-methoxyphenylacetylen

4-methoxy-2-(methylthio)benzenediazonium tetrafluoroborate

4-methoxy-2-(methylthio)benzenediazonium tetrafluoroborate

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

Conditions
ConditionsYield
With eosin y In dimethyl sulfoxide for 14h; Irradiation;70%
With titanium(III) chloride In N,N-dimethyl-formamide at -25 - 20℃; Cycloaddition;60%
6-methoxy-2-(4-methoxyphenyl)-3-methylsulfinylbenzo[b]thiophene

6-methoxy-2-(4-methoxyphenyl)-3-methylsulfinylbenzo[b]thiophene

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

Conditions
ConditionsYield
With Octanethiol; trifluorormethanesulfonic acid In dichloromethane at 40℃; for 12h;70%
α-(3-methoxyphenyl-thio)-4-methoxyacetophenone
63675-73-0

α-(3-methoxyphenyl-thio)-4-methoxyacetophenone

A

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

B

2-(4'-methoxyphenyl)-4-methoxybenzo[b]thiophene
90433-54-8

2-(4'-methoxyphenyl)-4-methoxybenzo[b]thiophene

Conditions
ConditionsYield
With PPA at 85 - 90℃; for 1h;A 69%
B n/a
With PPA at 70℃;A 68%
B 23%
With PPA Heating; Yield given; Yields of byproduct given;
With polyphosphoric acid at 65 - 90℃; for 2h; Product distribution / selectivity;
6-methoxy-benzo[b]thiophene
90560-10-4

6-methoxy-benzo[b]thiophene

1-bromo-4-methoxy-benzene
104-92-7

1-bromo-4-methoxy-benzene

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

Conditions
ConditionsYield
With potassium acetate; {1,3-bis(2,6-diethylaniline)acenaphthylenyl-4,5-imidazolium-2-ylidene}PdCl2-(pyridine) In N,N-dimethyl acetamide at 130℃; for 12h; Inert atmosphere; Sealed tube;67%
2-fluoro-4-methoxy-benzaldehyde
331-64-6

2-fluoro-4-methoxy-benzaldehyde

p-methoxybenzylmercaptan
6258-60-2

p-methoxybenzylmercaptan

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 60 - 160℃; for 66h;55%
4-Methoxy-2-methylsulfenylaniline
1658-03-3

4-Methoxy-2-methylsulfenylaniline

phenylacetylene
536-74-3

phenylacetylene

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

Conditions
ConditionsYield
With tert.-butylnitrite In nitromethane at 80℃; for 12h; Schlenk technique; Inert atmosphere;50%
4-methoxyphenylboronic acid
5720-07-0

4-methoxyphenylboronic acid

3-iodo-6-methoxy-benzo[b]thiophene

3-iodo-6-methoxy-benzo[b]thiophene

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

Conditions
ConditionsYield
With sodium carbonate; tetrakis(triphenylphosphine) palladium(0) at 100℃; for 4h; Yield given;
1-bromo-4-methoxy-benzene
104-92-7

1-bromo-4-methoxy-benzene

6-methoxy-benzo[b]thiophen-2-yl boronic acid
182133-35-3

6-methoxy-benzo[b]thiophen-2-yl boronic acid

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate Suzuki coupling reaction;
6-methoxy-benzo[b]thiophene
90560-10-4

6-methoxy-benzo[b]thiophene

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: BuLi
1.2: B(OiPr)3
1.3: HCl
2.1: Na2CO3; Pd(PPh3)4
View Scheme
Multi-step reaction with 2 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 2.08 h / -78 °C / Inert atmosphere
1.2: 3 h / -78 - 20 °C / Inert atmosphere
2.1: N-Bromosuccinimide / tetrahydrofuran; hexane / 3 h / -78 °C / Inert atmosphere
2.2: 0.5 h / -78 - 20 °C / Inert atmosphere
View Scheme
3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

o-CHO-C6H4-X (X=NO2 or F)

o-CHO-C6H4-X (X=NO2 or F)

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: K2CO3 / acetone
1.2: BF3*Et2O
2.1: BuLi
2.2: B(OiPr)3
2.3: HCl
3.1: Na2CO3; Pd(PPh3)4
View Scheme
6-methoxybenzothiazol-2-ylamine
1747-60-0

6-methoxybenzothiazol-2-ylamine

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: aq. KOH / 17 h / Heating
1.2: 92 percent / 1 h / 20 °C
2.1: aq. HCl; NaNO2
2.2: 57 percent / aq. HBF4 / 0 - 20 °C
3.1: 60 percent / TiCl3 / dimethylformamide / -25 - 20 °C
View Scheme
Multi-step reaction with 3 steps
1.1: potassium hydroxide / water / 17 h / Reflux
1.2: 1 h / 20 °C
2.1: fluoroboric acid; sodium nitrite / water / 0.67 h / 0 - 5 °C / Enzymatic reaction
3.1: eosin y / dimethyl sulfoxide / 14 h / Irradiation
View Scheme
Multi-step reaction with 2 steps
1: potassium hydroxide; methyl iodide
2: tert.-butylnitrite / nitromethane / 12 h / 80 °C / Schlenk technique; Inert atmosphere
View Scheme
4-Methoxy-2-methylsulfenylaniline
1658-03-3

4-Methoxy-2-methylsulfenylaniline

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: aq. HCl; NaNO2
1.2: 57 percent / aq. HBF4 / 0 - 20 °C
2.1: 60 percent / TiCl3 / dimethylformamide / -25 - 20 °C
View Scheme
Multi-step reaction with 2 steps
1: fluoroboric acid; sodium nitrite / water / 0.67 h / 0 - 5 °C / Enzymatic reaction
2: eosin y / dimethyl sulfoxide / 14 h / Irradiation
View Scheme
4-methoxy-aniline
104-94-9

4-methoxy-aniline

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: 62 percent / Br2; AcOH / 0.75 h / 20 °C
2.1: aq. KOH / 17 h / Heating
2.2: 92 percent / 1 h / 20 °C
3.1: aq. HCl; NaNO2
3.2: 57 percent / aq. HBF4 / 0 - 20 °C
4.1: 60 percent / TiCl3 / dimethylformamide / -25 - 20 °C
View Scheme
Multi-step reaction with 3 steps
1.1: 51 percent / CuI / o-xylene / 94 h / 145 °C
2.1: aq. HCl; NaNO2
2.2: 57 percent / aq. HBF4 / 0 - 20 °C
3.1: 60 percent / TiCl3 / dimethylformamide / -25 - 20 °C
View Scheme
Multi-step reaction with 4 steps
1.1: acetic acid; bromine / 3 h / 10 °C
2.1: potassium hydroxide / water / 17 h / Reflux
2.2: 1 h / 20 °C
3.1: fluoroboric acid; sodium nitrite / water / 0.67 h / 0 - 5 °C / Enzymatic reaction
4.1: eosin y / dimethyl sulfoxide / 14 h / Irradiation
View Scheme
1-(1,1-Dichloro-ethyl)-4-methoxy-benzene
69151-26-4

1-(1,1-Dichloro-ethyl)-4-methoxy-benzene

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NaNH2; NH3
2: 60 percent / TiCl3 / dimethylformamide / -25 - 20 °C
View Scheme
1-(4-methoxyphenyl)ethanone
100-06-1

1-(4-methoxyphenyl)ethanone

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: PCl5 / benzene
2: NaNH2; NH3
3: 60 percent / TiCl3 / dimethylformamide / -25 - 20 °C
View Scheme
Multi-step reaction with 2 steps
1.1: bromine / methanol / 2.5 h / 10 °C
1.2: 4 h / 0 - 20 °C
2.1: polyphosphoric acid / 2 h / 65 - 90 °C
View Scheme
3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NaOH / ethanol
2: polyphosphoric acid / Heating
View Scheme
Multi-step reaction with 2 steps
1: 80 percent / KOH / aq. ethanol; ethyl acetate / 3 h / Ambient temperature
2: 68 percent / polyphosphoric acid / 70 °C
View Scheme
Multi-step reaction with 2 steps
1: 80.4 percent / KOH / ethanol; H2O; ethyl acetate / Ambient temperature
2: 69 percent / PPA / 1 h / 85 - 90 °C
View Scheme
2-Bromo-4'-methoxyacetophenone
2632-13-5

2-Bromo-4'-methoxyacetophenone

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NaOH / ethanol
2: polyphosphoric acid / Heating
View Scheme
Multi-step reaction with 2 steps
1: 80 percent / KOH / aq. ethanol; ethyl acetate / 3 h / Ambient temperature
2: 68 percent / polyphosphoric acid / 70 °C
View Scheme
Multi-step reaction with 2 steps
1: 80.4 percent / KOH / ethanol; H2O; ethyl acetate / Ambient temperature
2: 69 percent / PPA / 1 h / 85 - 90 °C
View Scheme
E/Z-t-butyl 4,4'-dimethoxystilbenyl sulfoxide

E/Z-t-butyl 4,4'-dimethoxystilbenyl sulfoxide

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene for 1.5h; Heating / reflux;
With toluene-4-sulfonic acid In toluene for 6h; Heating / reflux;
3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

2-Bromo-4'-methoxyacetophenone
2632-13-5

2-Bromo-4'-methoxyacetophenone

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

Conditions
ConditionsYield
With potassium hydroxide; PPA In ethanol; water; ethyl acetate
With potassium hydroxide; PPA In ethanol; water; ethyl acetate
Lawessons reagent
19172-47-5

Lawessons reagent

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

Conditions
ConditionsYield
With methanesulfonic acid In chlorobenzene
With methanesulfonic acid In chlorobenzene
4-methoxybenzo[b]thiophene
3781-90-6

4-methoxybenzo[b]thiophene

a-(-methoxyphenylthio)-4-methoxyacetophenone

a-(-methoxyphenylthio)-4-methoxyacetophenone

acetophenone
98-86-2

acetophenone

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

Conditions
ConditionsYield
With PPA; phosphoric acid In water; toluene
3-methoxybenzenethiol
15570-12-4

3-methoxybenzenethiol

2-Bromo-4'-methoxyacetophenone
2632-13-5

2-Bromo-4'-methoxyacetophenone

A

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

B

α-(3-methoxyphenyl-thio)-4-methoxyacetophenone
63675-73-0

α-(3-methoxyphenyl-thio)-4-methoxyacetophenone

Conditions
ConditionsYield
With potassium hydroxide In ethanol; water; Petroleum etherA 78.5 g (76%)
B n/a
2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

1,2-bis(4-methoxyphenyl)ethane
1657-55-2

1,2-bis(4-methoxyphenyl)ethane

Conditions
ConditionsYield
W-2 Raney Ni In ethanol for 0.5h; Heating;100%
2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

3-bromo-6-methoxy-2-(4-methoxyphenyl)benzo[b]thiophene
176672-06-3

3-bromo-6-methoxy-2-(4-methoxyphenyl)benzo[b]thiophene

Conditions
ConditionsYield
With bromine In chloroform at 60℃;100%
With bromine In chloroform at 60℃;100%
With N-Bromosuccinimide In tetrahydrofuran at 0 - 20℃; for 3h;97%
2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

4-chlorobenzoyl chloride
586-75-4

4-chlorobenzoyl chloride

4-Bromophenyl-[6-methoxy-2-(4-methoxy-phenyl)benzo[b]thien-3-yl]methanone
206434-78-8

4-Bromophenyl-[6-methoxy-2-(4-methoxy-phenyl)benzo[b]thien-3-yl]methanone

Conditions
ConditionsYield
With aluminum (III) chloride In dichloromethane at 0 - 25℃; for 3.5h; Friedel-Crafts Acylation;96%
With copper(II) bis(trifluoromethanesulfonate) at 100℃; for 2h; Friedel Crafts acylation; Ionic liquid; Inert atmosphere;79%
With aluminium trichloride In dichloromethane65%
4-(2-chloro-ethoxy)-benzoyl chloride
65136-50-7

4-(2-chloro-ethoxy)-benzoyl chloride

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

[4-(2-chloro-ethoxy)-phenyl]-[6-methoxy-2-(4-methoxy-phenyl)-benzo[b]thiophen-3-yl]-methanone

[4-(2-chloro-ethoxy)-phenyl]-[6-methoxy-2-(4-methoxy-phenyl)-benzo[b]thiophen-3-yl]-methanone

Conditions
ConditionsYield
With aluminum (III) chloride In dichloromethane at 50℃; for 12h; Friedel-Crafts Acylation; Inert atmosphere;95%
acetic anhydride
108-24-7

acetic anhydride

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

6-acetoxy-2-(4-acetoxyphenyl)benzo[b]thiophene
84449-63-8

6-acetoxy-2-(4-acetoxyphenyl)benzo[b]thiophene

Conditions
ConditionsYield
Stage #1: 2-(4'-methoxyphenyl)-6-methoxybenzothiophene With pyridine; hydrogenchloride; tributyl-amine at 170 - 180℃;
Stage #2: With water In ethyl acetate for 0.25h;
Stage #3: acetic anhydride With triethylamine In ethyl acetate at 25 - 65℃; for 1h;
91.1%
sodium hexafluoroantimonate

sodium hexafluoroantimonate

C15H24N3O2S(1+)*F6Sb(1-)

C15H24N3O2S(1+)*F6Sb(1-)

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

C27H33N2O2S2(1+)*F6Sb(1-)

C27H33N2O2S2(1+)*F6Sb(1-)

Conditions
ConditionsYield
Stage #1: C15H24N3O2S(1+)*F6Sb(1-); 2-(4'-methoxyphenyl)-6-methoxybenzothiophene In acetonitrile at 70℃; for 16h; Inert atmosphere;
Stage #2: sodium hexafluoroantimonate In dichloromethane; water for 0.0833333h; Inert atmosphere; regioselective reaction;
90%
2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

6-hydroxy-2-(4-hydroxyphenyl)benzo[B]-thiophene
63676-22-2

6-hydroxy-2-(4-hydroxyphenyl)benzo[B]-thiophene

Conditions
ConditionsYield
With boron tribromide In dichloromethane at 0 - 5℃;89.3%
With pyridine hydrochloride at 190℃; for 1h;87%
With pyridine hydrochloride at 180℃; for 1h;87%
2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

3,4,5-triethoxybenzoyl chloride
50915-97-4

3,4,5-triethoxybenzoyl chloride

3-(3',4',5'-triethoxybenzoyl)-2-(4'-methoxyphenyl)-6-methoxybenzo[b]-thiophene

3-(3',4',5'-triethoxybenzoyl)-2-(4'-methoxyphenyl)-6-methoxybenzo[b]-thiophene

Conditions
ConditionsYield
With aluminium trichloride In dichloromethane for 0.5h;88%
AlCl3 In dichloromethane; water
aluminum (III) chloride In dichloromethane for 0.75h;
2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

dimethyl sulfoxide
67-68-5

dimethyl sulfoxide

6-methoxy-2-(4-methoxyphenyl)-3-methylthiobenzo[b]thiophene

6-methoxy-2-(4-methoxyphenyl)-3-methylthiobenzo[b]thiophene

Conditions
ConditionsYield
Stage #1: 2-(4'-methoxyphenyl)-6-methoxybenzothiophene; dimethyl sulfoxide With trifluoromethylsulfonic anhydride In dichloromethane at -30 - 20℃; for 1.75h; Inert atmosphere;
Stage #2: With diethylamine In dichloromethane at 20℃; for 6h; Inert atmosphere;
88%
4-fluorobenzoyl chloride
403-43-0

4-fluorobenzoyl chloride

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

6-methoxy-2-(4-methoxyphenyl)-3-(4-fluorobenzoyl)benzo[b]thiophene
206434-77-7

6-methoxy-2-(4-methoxyphenyl)-3-(4-fluorobenzoyl)benzo[b]thiophene

Conditions
ConditionsYield
With aluminum (III) chloride In dichloromethane at 0℃; for 72h; Inert atmosphere;87%
With aluminium trichloride In dichloromethane74%
With aluminum (III) chloride In dichloromethane for 18h; Friedel-Crafts Acylation; Inert atmosphere;69%
4-azidobenzoyl chloride
14848-01-2

4-azidobenzoyl chloride

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

3-(4-Azidobenzoyl)-6-methoxy-2-(4-methoxyphenyl)benzothiophene
133295-96-2

3-(4-Azidobenzoyl)-6-methoxy-2-(4-methoxyphenyl)benzothiophene

Conditions
ConditionsYield
With titanium tetrachloride In dichloromethane at 20℃; for 5.5h; in the dark;82%
2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

3,4-dimethoxybenzoic acid chloride
3535-37-3

3,4-dimethoxybenzoic acid chloride

3-(3',4'-dimethoxybenzoyl)-2-(4'-methoxyphenyl)-6-methoxybenzo[b]thiophene

3-(3',4'-dimethoxybenzoyl)-2-(4'-methoxyphenyl)-6-methoxybenzo[b]thiophene

Conditions
ConditionsYield
aluminum (III) chloride In dichloromethane for 7h;76%
aluminum (III) chloride In dichloromethane for 7h;76%
AlCl3 In dichloromethane; water
2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

ethyl 4-(chlorocarbonyl)benzoate
27111-45-1

ethyl 4-(chlorocarbonyl)benzoate

3-<(4'-ethoxycarbonyl)benzoyl>-6-methoxy-2-(4-methoxyphenyl)benzothiophene
141563-37-3

3-<(4'-ethoxycarbonyl)benzoyl>-6-methoxy-2-(4-methoxyphenyl)benzothiophene

Conditions
ConditionsYield
With aluminium trichloride In dichloromethane for 12h;73%
4-fluorobenzoyl chloride
403-43-0

4-fluorobenzoyl chloride

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

C29H20F2O4S

C29H20F2O4S

Conditions
ConditionsYield
With aluminum (III) chloride In dichloromethane at 20℃; for 18h; Friedel-Crafts Acylation; Inert atmosphere;70%
2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

p-benzenesulfonyloxybenzoyl chloride

p-benzenesulfonyloxybenzoyl chloride

benzenesulfonic acid-4-[6-methoxy-2-(4-methoxy-phenyl)-benzo[b]thiophene-3-carbonyl]-phenyl ester
1293362-49-8

benzenesulfonic acid-4-[6-methoxy-2-(4-methoxy-phenyl)-benzo[b]thiophene-3-carbonyl]-phenyl ester

Conditions
ConditionsYield
iron(III) sulfate pentahydrate; iron In toluene at 100 - 111℃; for 5.5h; Product distribution / selectivity;66.4%
Stage #1: 2-(4'-methoxyphenyl)-6-methoxybenzothiophene; p-benzenesulfonyloxybenzoyl chloride; iron(III) sulfate pentahydrate; iron In toluene at 99 - 114℃;
Stage #2: With sodium hydroxide In water; toluene at 62 - 66℃; Product distribution / selectivity; Inert atmosphere;
66.4%
With iron; iron(III) sulfate pentahydrate In toluene at 98 - 111℃; for 16.5h; Product distribution / selectivity; Inert atmosphere;66.4%
iron(III) chloride In toluene at 23 - 63℃; for 6h; Product distribution / selectivity; Friedel Crafts Acylation;
3,4,5-Trimethoxybenzoyl chloride
4521-61-3

3,4,5-Trimethoxybenzoyl chloride

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

(6-methoxy-2-(4-methoxyphenyl)benzo[b]thiophen-3-yl)(3,4,5-trimethoxyphenyl)methanone

(6-methoxy-2-(4-methoxyphenyl)benzo[b]thiophen-3-yl)(3,4,5-trimethoxyphenyl)methanone

Conditions
ConditionsYield
With aluminium trichloride In dichloromethane for 5h;63%
With aluminium trichloride In dichloromethane
AlCl3 In dichloromethane; water
aluminum (III) chloride In dichloromethane for 5h;
2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

2,6-dimethoxybenzoyl chloride
1989-53-3

2,6-dimethoxybenzoyl chloride

3-(2', 6'-dimethoxybenzoyl)-2-(4'-methoxyphenyl)-6-methoxybenzo[b]thiophene

3-(2', 6'-dimethoxybenzoyl)-2-(4'-methoxyphenyl)-6-methoxybenzo[b]thiophene

Conditions
ConditionsYield
With aluminium trichloride In dichloromethane for 6h;60%
With aluminium trichloride In dichloromethane
AlCl3 In dichloromethane; water
aluminum (III) chloride In dichloromethane for 6h;
2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

4-iodobenzoic acid chloride
1711-02-0

4-iodobenzoic acid chloride

(4-iodophenyl)(6-methoxy-2-(4-methoxyphenyl)benzo[b]thiophen-3-yl)methanone
166975-67-3

(4-iodophenyl)(6-methoxy-2-(4-methoxyphenyl)benzo[b]thiophen-3-yl)methanone

Conditions
ConditionsYield
With aluminum (III) chloride In dichloromethane at 20℃; for 24h; Friedel-Crafts Acylation; Inert atmosphere;60%
With aluminum (III) chloride In dichloromethane for 3h;
4-(toluene-4-sulfonyloxy)-benzoyl chloride
64675-83-8

4-(toluene-4-sulfonyloxy)-benzoyl chloride

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

toluene-4-sulfonic acid 4-[6-methoxy-2-(4-methoxyphenyl)benzo[b]thiophene-3-carbonyl]phenyl ester
1293362-53-4

toluene-4-sulfonic acid 4-[6-methoxy-2-(4-methoxyphenyl)benzo[b]thiophene-3-carbonyl]phenyl ester

Conditions
ConditionsYield
iron(III) sulfate pentahydrate; iron In toluene for 10.5h; Reflux;58.4%
iron(III) sulfate pentahydrate; iron In toluene for 10.5h; Friedel Crafts Acylation; Reflux;
Stage #1: 4-(toluene-4-sulfonyloxy)-benzoyl chloride; 2-(4'-methoxyphenyl)-6-methoxybenzothiophene; iron(III) sulfate pentahydrate; iron In toluene for 10.5h; Reflux;
Stage #2: With sodium hydroxide In water; toluene at 60 - 70℃; for 0.75h; Product distribution / selectivity;
With iron; iron(III) sulfate pentahydrate In toluene for 10.5h; Reflux;
6-bromohexanoyl chloride
22809-37-6

6-bromohexanoyl chloride

2-(4'-methoxyphenyl)-6-methoxybenzothiophene
63675-74-1

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

3-(6-bromohexanoyl)-6-methoxy-2-(4-methoxyphenyl)benzo[b]thiophen
220469-39-6

3-(6-bromohexanoyl)-6-methoxy-2-(4-methoxyphenyl)benzo[b]thiophen

Conditions
ConditionsYield
With aluminium trichloride In 1,2-dichloro-ethane for 1h; Ambient temperature;55%
AlCl3 In 1,2-dichloro-ethane55%
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