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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Cilostazol

Cas:73963-72-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Cilostazol supplier in China

Cas:73963-72-1

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

High purity Cilostazol with good quality

Cas:73963-72-1

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Manufacturers

inquiry

Wuhan Fortuna Chemical Co.,Ltd

Unique advantages of Cilostazol Cas 73963-72-1 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White or almost white crystalline powder Storage:Cool dry place Package:25k

Factory supply Cilostazol Cas 73963-72-1 with top quality and fast delivery

Cas:73963-72-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

Jinlan Pharm-Drugs Technology Co.,Limited (with its export company Hangzhou Royall Import & Export Co.,Ltd.)is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int’l Airport and Shangha

Cilostazol CAS No.73963-72-1

Cas:73963-72-1

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Cilostazol

Cas:73963-72-1

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% Cilostazol 73963-72-1 GMP Manufacturer

Cas:73963-72-1

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Cilostazol

Cas:73963-72-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

LIDE PHARMACEUTICALS LIMITED

LIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.

CILOSTAZOL

Cas:73963-72-1

Min.Order:1 Kilogram

FOB Price: $0.9 / 1.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

Cilostazol

Cas:73963-72-1

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 73963-72-1 with best quality

Cas:73963-72-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Hot Sell Factory Supply Raw Material CAS 73963-72-1 ,Cilostazol

Cas:73963-72-1

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product name: Cilostazol CAS No.: 73963-72-1 Molecular formula;C20H27N5O2 Molecular weight:369.46 Appearance : white crystalline powder Purity:99.6% Appearance:White powder Storage:Store in cool and dry place, away from sun light. Packag

Cilostazol

Cas:73963-72-1

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White crystal powder Storage:Store in sealed containers at c

Active Pharmaceutical Ingredients CAS 73963-72-1 Cilostazol

Cas:73963-72-1

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Cilostazol 73963-72-1

Cas:73963-72-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Qingdao Beluga Import and Export Co., LTD

Cilostazol CAS:73963-72-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates,

Cilostazol CAS:73963-72-1

Cas:73963-72-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Cilostazol

Cas:73963-72-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Mojin Biotechnology Co.,Ltd

Company information: Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in chemical raw materials and chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big custo

Cilostazol CAS No.73963-72-1

Cas:73963-72-1

Min.Order:1 Kilogram

FOB Price: $8.0 / 10.0

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Cilostazol

Cas:73963-72-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Zenuo Biological Medicine Technology Co Ltd

Product Name: Cilostazol Synonyms: CILASTAZOL;CILOSTAZOL;CILOSTAZOLE;RETAL;OPC 13013;OPC 21;PLETAL;PLETAAL CAS: 73963-72-1 MF: C20H27N5O2 MW: 369.46 EINECS: 689-122-9 Product Categories: -;Active Pharmaceutical Ingredients;Intermediate

Cilostazol free sample available best quality

Cas:73963-72-1

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

Cilostazol

Cas:73963-72-1

Min.Order:1 Gram

FOB Price: $62.0

Type:Trading Company

inquiry

Hubei Yuanmeng Biological Technology Co., Ltd.

Hubei Yuanmeng Biological Technology Co., Ltd., which is located in Wuhan, China. We are specializing in the exportation of APIs, and plant extracts ect. Our products has been exported to America, Australia, Brazil, the Europe, Middle East and other

High Purity Cilostazol CAS 73963-72-1 with Fast Shipment

Cas:73963-72-1

Min.Order:1 Kilogram

FOB Price: $3.0 / 5.0

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Cilostazol

Cas:73963-72-1

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

The intermediate of Cilostazol(N-Cyclohexyl-5-(4-chlorobutyl)tetrazol)

Cas:73963-72-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

afine-Cilostazol

Cas:73963-72-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shaanxi New nine Material Technology Co., Ltd.

Our Advantage & Service 1.Top quality: Using high quality material and establishing a strict quality control system,assigning specific persons in charge of each part of production,from raw material purchase to assembly. 2 Professional R&D

Cilostazol CAS NO.73963-72-1

Cas:73963-72-1

Min.Order:10 Gram

FOB Price: $5.0 / 10.0

Type:Trading Company

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

Cilostazol

Cas:73963-72-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

Cilostazol/High quality/Best price

Cas:73963-72-1

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Cilostazol

Cas:73963-72-1

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Synthetic route

cilostazol bisulfate
877303-65-6

cilostazol bisulfate

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

Conditions
ConditionsYield
With sodium hydroxide In chloroform; water Product distribution / selectivity;98.7%
cilostazol oxalate
877303-63-4

cilostazol oxalate

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

Conditions
ConditionsYield
With sodium hydroxide In chloroform; water Product distribution / selectivity;97.9%
cilostazol malate
877303-64-5

cilostazol malate

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

Conditions
ConditionsYield
With sodium hydroxide In chloroform; water Product distribution / selectivity;97.8%
C20H26BrN5O2

C20H26BrN5O2

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); N-ethyl-N,N-diisopropylamine In acetonitrile for 10h; Reagent/catalyst; Solvent; Temperature; Inert atmosphere; Reflux;96%
3,4-dihydro-6-hydroxy-2(1H)-quinolinone
54197-66-9

3,4-dihydro-6-hydroxy-2(1H)-quinolinone

1-cyclohexyl-5-(4-chlorobutyl)-1,2,3,4-tetrazole
73963-42-5

1-cyclohexyl-5-(4-chlorobutyl)-1,2,3,4-tetrazole

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

Conditions
ConditionsYield
With potassium carbonate; sodium hydroxide; sodium sulfite In ethanol for 8h; Reflux;92.5%
With potassium carbonate; sodium hydroxide; sodium sulfite In water at 92℃; for 6h; Solvent; Reagent/catalyst; Temperature;91.5%
With potassium hydroxide In ethanol at 80℃; for 12h; Solvent; Reagent/catalyst; Temperature; Inert atmosphere; Sealed tube;90%
3,4-dihydro-6-hydroxy-2(1H)-quinolinone
54197-66-9

3,4-dihydro-6-hydroxy-2(1H)-quinolinone

1-cyclohexyl-5-(4-chlorobutyl)-1,2,3,4-tetrazole
73963-42-5

1-cyclohexyl-5-(4-chlorobutyl)-1,2,3,4-tetrazole

A

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)-butoxy]-1-[4-(1-cyclohexyl-1H-tetrazol-5-yl)-butyl]-3,4-dihydro-1H-quinolin-2-one
865792-18-3

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)-butoxy]-1-[4-(1-cyclohexyl-1H-tetrazol-5-yl)-butyl]-3,4-dihydro-1H-quinolin-2-one

B

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

C

OPC 13015
73963-62-9

OPC 13015

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In ethanol at 75 - 80℃;A n/a
B 89%
C n/a
C20H26ClN5O2

C20H26ClN5O2

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

Conditions
ConditionsYield
With bis(triphenylphosphine)nickel(II) chloride; N-ethyl-N,N-diisopropylamine In 1,4-dioxane at 25℃; for 8h; Inert atmosphere;88%
C20H26IN5O2

C20H26IN5O2

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

Conditions
ConditionsYield
With bis(triphenylphosphine)nickel(II) chloride; N-ethyl-N,N-diisopropylamine In 1,4-dioxane at 25℃; for 8h; Inert atmosphere;85%
1-cyclohexyl-5-(4-chlorobutyl)-1,2,3,4-tetrazole
73963-42-5

1-cyclohexyl-5-(4-chlorobutyl)-1,2,3,4-tetrazole

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

Conditions
ConditionsYield
Stage #1: 3,4-dihydro-6-hydroxy-2(1H)-quinolinone With 1,8-diazabicyclo[5.4.0]undec-7-ene In ethanol for 6.5h; Heating / reflux; Molecular sieve;
Stage #2: 1-cyclohexyl-5-(4-chlorobutyl)-1,2,3,4-tetrazole In ethanol for 6.5h; Product distribution / selectivity; Heating / reflux;
40.2%
Multi-step reaction with 4 steps
1: sodium hydroxide / butan-1-ol / 8 h / Reflux
2: iron; ammonium chloride; acetic acid / methanol; water / 5 h / 45 °C / Reflux
3: triethylamine / dichloromethane / 3 h / 0 °C
4: N-ethyl-N,N-diisopropylamine; tetrakis(triphenylphosphine) palladium(0) / acetonitrile / 10 h / Inert atmosphere; Reflux
View Scheme
4-methoxy-aniline
104-94-9

4-methoxy-aniline

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: potassium carbonate / acetone / 0.5 h
2: aluminum (III) chloride / N,N-dimethyl acetamide / 2 h / 150 °C
3: potassium hydroxide / ethanol / 12 h / 80 °C / Inert atmosphere; Sealed tube
View Scheme
3-bromo-4-nitrophenol
5470-65-5

3-bromo-4-nitrophenol

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: sodium hydroxide / butan-1-ol / 8 h / Reflux
2: iron; ammonium chloride; acetic acid / methanol; water / 5 h / 45 °C / Reflux
3: triethylamine / dichloromethane / 3 h / 0 °C
4: N-ethyl-N,N-diisopropylamine; tetrakis(triphenylphosphine) palladium(0) / acetonitrile / 10 h / Inert atmosphere; Reflux
View Scheme
C17H22BrN5O3

C17H22BrN5O3

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: iron; ammonium chloride; acetic acid / methanol; water / 5 h / 45 °C / Reflux
2: triethylamine / dichloromethane / 3 h / 0 °C
3: N-ethyl-N,N-diisopropylamine; tetrakis(triphenylphosphine) palladium(0) / acetonitrile / 10 h / Inert atmosphere; Reflux
View Scheme
6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

oxalic acid
144-62-7

oxalic acid

cilostazol oxalate
877303-63-4

cilostazol oxalate

Conditions
ConditionsYield
In acetone at 20 - 25℃; for 3h;97%
6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

cilostazol bisulfate
877303-65-6

cilostazol bisulfate

Conditions
ConditionsYield
With sulfuric acid In Isopropyl acetate at 20 - 25℃; for 3h; Product distribution / selectivity;94%
With sulfuric acid In acetone at 20 - 25℃; for 3h;92%
With sulfuric acid In butanone at 20 - 25℃; for 3h; Product distribution / selectivity;91%
6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

maleic acid
110-16-7

maleic acid

cilostazol malate
877303-64-5

cilostazol malate

Conditions
ConditionsYield
In acetone at 20 - 25℃; for 3h;90%
6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

ethyl iodide
75-03-6

ethyl iodide

6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-1-ethyl-3,4-dihydroquinolin-2(1H)-one

6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-1-ethyl-3,4-dihydroquinolin-2(1H)-one

Conditions
ConditionsYield
Stage #1: 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril With sodium hydride In mineral oil at 0℃; for 0.5h; Inert atmosphere;
Stage #2: ethyl iodide In mineral oil at 0 - 20℃; for 12h; Inert atmosphere;
81%
6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

A

OPC-13326
93632-84-9

OPC-13326

3,4-Dihydro-6-<4-<1-(cis-2-hydroxycyclohexyl)-1H-tetrazol-5-yl>butoxy>-2(1H)-quinolinone
87153-03-5, 87153-05-7

3,4-Dihydro-6-<4-<1-(cis-2-hydroxycyclohexyl)-1H-tetrazol-5-yl>butoxy>-2(1H)-quinolinone

3,4-Dihydro-6-<4-<1-(trans-3-hydroxycyclohexyl)-1H-tetrazol-5-yl>butoxy>-2(1H)-quinolinone
98360-32-8, 98360-33-9

3,4-Dihydro-6-<4-<1-(trans-3-hydroxycyclohexyl)-1H-tetrazol-5-yl>butoxy>-2(1H)-quinolinone

3,4-Dihydro-6-<4-<1-(cis-3-hydroxycyclohexyl)-1H-tetrazol-5-yl>butoxy>-2(1H)-quinolinone
98360-32-8, 98360-33-9

3,4-Dihydro-6-<4-<1-(cis-3-hydroxycyclohexyl)-1H-tetrazol-5-yl>butoxy>-2(1H)-quinolinone

E

OPC 13213
87153-04-6

OPC 13213

F

OPC 13217
87153-06-8

OPC 13217

Conditions
ConditionsYield
metabolism studies, pharmacokinetic;
6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

1-cyclohexyl-5-(4-chlorobutyl)-1,2,3,4-tetrazole
73963-42-5

1-cyclohexyl-5-(4-chlorobutyl)-1,2,3,4-tetrazole

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)-butoxy]-1-[4-(1-cyclohexyl-1H-tetrazol-5-yl)-butyl]-3,4-dihydro-1H-quinolin-2-one
865792-18-3

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)-butoxy]-1-[4-(1-cyclohexyl-1H-tetrazol-5-yl)-butyl]-3,4-dihydro-1H-quinolin-2-one

Conditions
ConditionsYield
With sodium hydride In DMF (N,N-dimethyl-formamide) at 10 - 15℃; for 27.5h;
4-bromo-3-(bromomethyl)butanoyl chloride
1227960-59-9

4-bromo-3-(bromomethyl)butanoyl chloride

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

1-(4-Bromo-3-(bromomethyl)butanoyl)-6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydroquinolin-2(1H)-one
1227960-58-8

1-(4-Bromo-3-(bromomethyl)butanoyl)-6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydroquinolin-2(1H)-one

Conditions
ConditionsYield
With triethylamine; dmap In tetrahydrofuran at 0 - 20℃; Inert atmosphere;
6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

Conditions
ConditionsYield
With iodine In 2-methyl-propan-1-ol at 24.84 - 119.84℃; Kinetics; Solvent; Temperature;
6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

2,3-dicyano-5,6-dichloro-p-benzoquinone
84-58-2

2,3-dicyano-5,6-dichloro-p-benzoquinone

C28H26ClN7O4

C28H26ClN7O4

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

2,3-dicyano-5,6-dichloro-p-benzoquinone
84-58-2

2,3-dicyano-5,6-dichloro-p-benzoquinone

CLZ-DDQ
1266615-52-4

CLZ-DDQ

Conditions
ConditionsYield
In acetonitrile for 298 - 313h; Kinetics; Solvent; Temperature;
2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

cilostazol gentisic acid
1352614-11-9

cilostazol gentisic acid

Conditions
ConditionsYield
In butanone at 20 - 50℃; for 120h; Solvent; Temperature; Time; Concentration;
In acetone at 20 - 40℃; for 168h;
2,5-dihydroxybenzoic acid.
490-79-9

2,5-dihydroxybenzoic acid.

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

cilostazol gentisic acid monohydrate
1352614-12-0

cilostazol gentisic acid monohydrate

Conditions
ConditionsYield
With water In nitromethane at 20 - 50℃; for 120h; Time;
4-hydroxysalicylic acid
89-86-1

4-hydroxysalicylic acid

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

cilostazol 2,4-dihydroxybenzoic acid
1352614-14-2

cilostazol 2,4-dihydroxybenzoic acid

Conditions
ConditionsYield
In nitromethane at 20 - 50℃; for 120h; Solvent; Temperature; Time; Concentration;
In acetone at 20℃; for 168h;
6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

4-hydroxy-benzoic acid
99-96-7

4-hydroxy-benzoic acid

cilostazol 4-hydroxybenzoic acid
1352614-13-1

cilostazol 4-hydroxybenzoic acid

Conditions
ConditionsYield
In nitromethane at 20 - 50℃; for 120h; Solvent; Temperature; Time; Concentration;
In acetone at 20℃; for 168h;
6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

heptakis-(2,3,6-tris-(2-hydroxypropyl))-β-cyclodextrin
128446-35-5

heptakis-(2,3,6-tris-(2-hydroxypropyl))-β-cyclodextrin

2C105H196O56*C20H27N5O2

2C105H196O56*C20H27N5O2

Conditions
ConditionsYield
In ethanol; water at 30℃;
6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril
73963-72-1

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydrocarbostyril

C29H38N6O3S

C29H38N6O3S

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: sodium hydride / mineral oil / 0.5 h / 0 °C / Inert atmosphere
1.2: 12 h / 0 - 20 °C / Inert atmosphere
2.1: 1,1,3,3-Tetramethyldisiloxane; bis(triphenylphosphine)carbonyliridium(I) chloride / dichloromethane / 0.5 h / 20 °C
2.2: 3 h / 20 °C
View Scheme
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