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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Loxoprofen sodium

Cas:80382-23-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Kono Chem Co.,Ltd

Product Name Loxoprofen sodium Other Name CS-600 Appearance White Powder Specification (COA) Item Index

CAS:80382-23-6 Loxoprofen sodium

Cas:80382-23-6

Min.Order:1 Kilogram

Negotiable

Type:Other

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C

Loxoprofen sodium manufacturer with low price

Cas:80382-23-6

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages for Loxoprofen sodium Cas 80382-23-6 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White to yellowish white crystals or crystalline powder Storage:Cool d

High quality Loxoprofen sodium Cas 80382-23-6 with best price and fast delivery

Cas:80382-23-6

Min.Order:1 Kilogram

FOB Price: $290.0 / 303.0

Type:Trading Company

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Hebei yanxi chemical co.,LTD.

Hebei yanxi chemical co., LTD is a professional research, development and production . enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low carbon environmental protection

Loxoprofen Sodium 80382-23-6

Cas:80382-23-6

Min.Order:1 Kilogram

FOB Price: $11.0 / 16.0

Type:Manufacturers

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Xi'an Quanao Biotech Co., Ltd.

Xi’an Quanao Biotech Co., Ltd. with 18 years experience in plant extract filed. Product grade: Medicine, Health care product, Cosmetics, Food, Beverage, Feed. Hot selling market: Europe, North America, South America, Middle East, Asia Pacifi

API 99% Loxoprofen Sodium Powder Cas 80382-23-6

Cas:80382-23-6

Min.Order:1 Kilogram

FOB Price: $249.0 / 269.0

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Loxoprofen Sodium

Cas:80382-23-6

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% Loxoprofen sodium 80382-23-6 GMP Manufacturer

Cas:80382-23-6

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Loxoprofen Sodium

Cas:80382-23-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c

Factory supply Loxoprofen sodium hydrate CAS 80382-23-6

Cas:80382-23-6

Min.Order:5 Kilogram

FOB Price: $100.0

Type:Trading Company

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Hubei DiBo chemical co., LTD

Chinese name: Loxoprofen Sodium Chinese alias: 2 - [4 - (2 - oxygen generation, methyl cyclopentane - 1) phenyl] propionic acid sodium dihydrate; LXP English name: Loxoprofen Sodium English alias: CS - 600; Loxoprofen sodium dihydrate; Sodium 2

Loxoprofen Sodium Manufacturer/Cas:80382-23-6 /99.9% High purity

Cas:80382-23-6

Min.Order:25 Metric Ton

FOB Price: $2.0

Type:Other

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LIDE PHARMACEUTICALS LIMITED

LIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.

Loxoprofen sodium

Cas:80382-23-6

Min.Order:1 Kilogram

FOB Price: $0.9 / 1.0

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

CAS 80382-23-6 Loxoprofen sodium

Cas:80382-23-6

Min.Order:1 Kilogram

FOB Price: $1000.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

CAS:80382-23-6 Loxoprofen Sodium for Anti-Inflammatory

Cas:80382-23-6

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 80382-23-6 with best quality

Cas:80382-23-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Loxoprofen Sodium 80382-23-6

Cas:80382-23-6

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Name: Loxoprofen Sodium CAS:80382-23-6 MF: C15H17NaO3 Appearance:White Powder Storage:Store in cool and dry place, away from sun light. Package:25kg Application:API Transportation:By sea or by air Port:Qingdao Port

Loxoprofen Sodium

Cas:80382-23-6

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best s

CAS 80382-23-6 pharmaceutical 99%min API Loxoprofe Sodium

Cas:80382-23-6

Min.Order:10 Gram

Negotiable

Type:Other

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Hangzhou Sartort Biopharma Co., Ltd

Appearance:White powder Storage:R.T Package:25kg/drum Application:Used as an anti-inflammatory analgesic Transportation:Express/Sea/Air Port:Any port in China

Factory price high quality Loxoprofen sodium

Cas:80382-23-6

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

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HANWAYS CHEMPHARM CO.,LIMITED

1.Prompt Goods; 2.Flexible payment terms; 3.Documents & Certificate support. Name: Loxoprofen sodium Molecular Structure: Formula: C15H17NaO3 Molecular Weight : 268.28 Synonyms: alpha-methyl-4-((2-oxocyclopentyl)methyl)benzeneacetatesodiu

Factory Supply Loxoprofen Sodium

Cas:80382-23-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1,In No Less five years exporting experience. 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Onchem specialized in APIs, chemical intermed

Loxoprofen sodium 99%

Cas:80382-23-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Loxoprofen sodium

Cas:80382-23-6

Min.Order:1 Kilogram

FOB Price: $186.0 / 210.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Loxoprofen sodium CAS: 80382-23-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic interm

Loxoprofen sodium CAS: 80382-23-6

Cas:80382-23-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Loxoprofen

Cas:80382-23-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Wonda Pharm Limited

1.high quality: quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed. 2.reasonable price: we provide high quality products wi

99% High Purity Loxoprofen Sodium factory bulk supply

Cas:80382-23-6

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:80382-23-6

Cas:80382-23-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Mojin Biotechnology Co.,Ltd

Product quality: Our company have high quality product , and also the product we have good manufacture . First of all, this product is of fine quality. Every finish should be checked by quality inspection system.And every one should be also tried

Factory Supply CAS 80382-23-6 Loxoprofen Sodium

Cas:80382-23-6

Min.Order:1 Kilogram

FOB Price: $20.0 / 30.0

Type:Trading Company

inquiry

Josun International Limited

Loxoprofen Sodium /Specification: JP or Internal Control Standard/ Min order quantity: 10kg / Packing: 10kg/drum Appearance:White to yellowish white crystals or crystalline powder Storage:Store in cool place. Package:10kg/drum or 15kg/dr

loxoprofen sodium JP with low price

Cas:80382-23-6

Min.Order:10 Kilogram

FOB Price: $250.0

Type:Other

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Lonwin Chemical Group Limited

Loxoprofen sodium CAS: 80382-23-6 Specification Test Item Analysis Specification Result Description It occurs as white to yellowish white crystals or crystalline power whit

Factory supply Loxoprofen sodium

Cas:80382-23-6

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Synthetic route

Conditions
ConditionsYield
With sodium hydroxide In ethanol; water for 2h; Reflux;96.6%
With methanol; sodium hydroxide for 1h;95%
With sodium hydroxide In ethanol at 50℃; for 2h;90.3%
2-(4-(bromomethyl)phenyl)propanoic acid
111128-12-2

2-(4-(bromomethyl)phenyl)propanoic acid

2-ethoxycarbonyl-1-cyclopentanone
611-10-9

2-ethoxycarbonyl-1-cyclopentanone

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate
80382-23-6

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate

Conditions
ConditionsYield
Stage #1: 2-[4-(bromomethyl)phenyl]propanoic acid; 2-ethoxycarbonyl-1-cyclopentanone With sodium hydroxide In N,N-dimethyl-formamide under 760.051 Torr; for 8h;
Stage #2: With hydrogenchloride In water; N,N-dimethyl-formamide pH=5 - 6; Further stages;
92%
1-(1-chloroethyl)-4-methylbenzene
2362-36-9

1-(1-chloroethyl)-4-methylbenzene

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate
80382-23-6

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: magnesium / tetrahydrofuran / 1.5 h / 20 - 30 °C / Inert atmosphere
2: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / dichloromethane / Reflux
3: sulfuric acid / 16 h / 0 - 5 °C
4: sodium periodate / N,N-dimethyl-formamide / 150 °C
5: hydrogenchloride / water / 4.5 h / Reflux
6: 5%-palladium/activated carbon; hydrogen / methanol / 14 h / 10 - 15 °C / 1125.11 Torr / Autoclave
7: sodium hydroxide / ethanol / 1 h / Reflux
View Scheme
(R,S)-2-(4'-methylphenyl) propionic acid
938-94-3

(R,S)-2-(4'-methylphenyl) propionic acid

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate
80382-23-6

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / dichloromethane / Reflux
2: sulfuric acid / 16 h / 0 - 5 °C
3: sodium periodate / N,N-dimethyl-formamide / 150 °C
4: hydrogenchloride / water / 4.5 h / Reflux
5: 5%-palladium/activated carbon; hydrogen / methanol / 14 h / 10 - 15 °C / 1125.11 Torr / Autoclave
6: sodium hydroxide / ethanol / 1 h / Reflux
View Scheme
2-(4-(bromomethyl)phenyl)propanoic acid
111128-12-2

2-(4-(bromomethyl)phenyl)propanoic acid

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate
80382-23-6

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: sulfuric acid / 16 h / 0 - 5 °C
2: sodium periodate / N,N-dimethyl-formamide / 150 °C
3: hydrogenchloride / water / 4.5 h / Reflux
4: 5%-palladium/activated carbon; hydrogen / methanol / 14 h / 10 - 15 °C / 1125.11 Torr / Autoclave
5: sodium hydroxide / ethanol / 1 h / Reflux
View Scheme
Multi-step reaction with 4 steps
1.1: sulfuric acid / toluene / 35 °C
1.2: 5 h / 281 °C
2.1: sodium methylate / toluene; dimethyl sulfoxide; methanol / 1.5 h / 2 - 5 °C
2.2: 5 - 18 °C
3.1: acetic acid; sulfuric acid / water / 2 h / 110 °C
4.1: sodium hydroxide / acetone / 30 °C / pH 7.2
View Scheme
Multi-step reaction with 4 steps
1: sulfuric acid / 6 h / 0 - 5 °C
2: potassium carbonate / toluene / 12 h / Reflux
3: hydrogen bromide; acetic acid / 8 h / Reflux
4: sodium hydroxide / ethanol; water / 3 h / 20 °C / pH 7 - 8
View Scheme
Multi-step reaction with 4 steps
1: sulfuric acid / 6 h / Cooling with ice
2: toluene / 12 h / 110 °C
3: sodium hydroxide; water / toluene / 2 h / 80 °C
4: sodium hydroxide / ethanol / 2 h / 50 °C
View Scheme
2-(4-bromomethylphenyl)propionic acid methyl ester
99807-54-2

2-(4-bromomethylphenyl)propionic acid methyl ester

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate
80382-23-6

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: sodium periodate / N,N-dimethyl-formamide / 150 °C
2: hydrogenchloride / water / 4.5 h / Reflux
3: 5%-palladium/activated carbon; hydrogen / methanol / 14 h / 10 - 15 °C / 1125.11 Torr / Autoclave
4: sodium hydroxide / ethanol / 1 h / Reflux
View Scheme
Multi-step reaction with 3 steps
1.1: sodium methylate / toluene; dimethyl sulfoxide; methanol / 1.5 h / 2 - 5 °C
1.2: 5 - 18 °C
2.1: acetic acid; sulfuric acid / water / 2 h / 110 °C
3.1: sodium hydroxide / acetone / 30 °C / pH 7.2
View Scheme
Multi-step reaction with 2 steps
1.1: sodium carbonate / acetone
2.1: hydrogenchloride / acetic acid / Reflux
2.2: Reflux
View Scheme
Multi-step reaction with 3 steps
1: potassium carbonate / toluene / 12 h / Reflux
2: hydrogen bromide; acetic acid / 8 h / Reflux
3: sodium hydroxide / ethanol; water / 3 h / 20 °C / pH 7 - 8
View Scheme
Multi-step reaction with 3 steps
1: toluene / 12 h / 110 °C
2: sodium hydroxide; water / toluene / 2 h / 80 °C
3: sodium hydroxide / ethanol / 2 h / 50 °C
View Scheme
2-(4-formylphenyl)propionic acid methyl ester
63476-54-0

2-(4-formylphenyl)propionic acid methyl ester

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate
80382-23-6

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: hydrogenchloride / water / 4.5 h / Reflux
2: 5%-palladium/activated carbon; hydrogen / methanol / 14 h / 10 - 15 °C / 1125.11 Torr / Autoclave
3: sodium hydroxide / ethanol / 1 h / Reflux
View Scheme
loxoprofen methyl ester
81762-92-7

loxoprofen methyl ester

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate
80382-23-6

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate

Conditions
ConditionsYield
With sodium hydroxide In ethanol for 1h; Reflux;35.36 g
C14H19BrO2

C14H19BrO2

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate
80382-23-6

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: magnesium; iodine / tetrahydrofuran / 20 - 25 °C
1.2: 0 - 20 °C
2.1: hydrogenchloride / methanol; water / 0 °C / Reflux
2.2: 0 °C / Reflux
3.1: sodium hydroxide; methanol / 1 h
View Scheme
1-bromomethyl-4-bromobenzene
589-15-1

1-bromomethyl-4-bromobenzene

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate
80382-23-6

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: sodium methylate / methanol / Reflux
2.1: acetic acid; hydrogenchloride / water / Reflux
3.1: pyridinium p-toluenesulfonate / methanol / 45 - 50 °C
4.1: magnesium; iodine / tetrahydrofuran / 20 - 25 °C
4.2: 0 - 20 °C
5.1: hydrogenchloride / methanol; water / 0 °C / Reflux
5.2: 0 °C / Reflux
6.1: sodium hydroxide; methanol / 1 h
View Scheme
methyl 2-oxocyclopentane-1-carboxylate
10472-24-9

methyl 2-oxocyclopentane-1-carboxylate

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate
80382-23-6

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: sodium methylate / methanol / Reflux
2.1: acetic acid; hydrogenchloride / water / Reflux
3.1: pyridinium p-toluenesulfonate / methanol / 45 - 50 °C
4.1: magnesium; iodine / tetrahydrofuran / 20 - 25 °C
4.2: 0 - 20 °C
5.1: hydrogenchloride / methanol; water / 0 °C / Reflux
5.2: 0 °C / Reflux
6.1: sodium hydroxide; methanol / 1 h
View Scheme
methyl 1-(4-bromobenzyl)-2-oxocyclopentanonecarboxylate

methyl 1-(4-bromobenzyl)-2-oxocyclopentanonecarboxylate

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate
80382-23-6

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: acetic acid; hydrogenchloride / water / Reflux
2.1: pyridinium p-toluenesulfonate / methanol / 45 - 50 °C
3.1: magnesium; iodine / tetrahydrofuran / 20 - 25 °C
3.2: 0 - 20 °C
4.1: hydrogenchloride / methanol; water / 0 °C / Reflux
4.2: 0 °C / Reflux
5.1: sodium hydroxide; methanol / 1 h
View Scheme
2-(4-bromobenzyl)cyclopentanone
500764-03-4

2-(4-bromobenzyl)cyclopentanone

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate
80382-23-6

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: pyridinium p-toluenesulfonate / methanol / 45 - 50 °C
2.1: magnesium; iodine / tetrahydrofuran / 20 - 25 °C
2.2: 0 - 20 °C
3.1: hydrogenchloride / methanol; water / 0 °C / Reflux
3.2: 0 °C / Reflux
4.1: sodium hydroxide; methanol / 1 h
View Scheme
methyl 2-(4-methylphenyl)propanoate
79443-97-3

methyl 2-(4-methylphenyl)propanoate

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate
80382-23-6

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane / Reflux
2.1: sodium carbonate / acetone
3.1: hydrogenchloride / acetic acid / Reflux
3.2: Reflux
View Scheme
C18H22O5

C18H22O5

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate
80382-23-6

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate

Conditions
ConditionsYield
Stage #1: C18H22O5 With hydrogenchloride In acetic acid Reflux;
Stage #2: With sodium hydroxide In ethanol Reflux;
cyclopentanone
120-92-3

cyclopentanone

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate
80382-23-6

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: toluene-4-sulfonic acid / toluene / 8 h / 110 °C
2: toluene / 12 h / 110 °C
3: sodium hydroxide; water / toluene / 2 h / 80 °C
4: sodium hydroxide / ethanol / 2 h / 50 °C
View Scheme
1-(N-morpholino)cyclopent-1-ene
936-52-7

1-(N-morpholino)cyclopent-1-ene

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate
80382-23-6

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: toluene / 12 h / 110 °C
2: sodium hydroxide; water / toluene / 2 h / 80 °C
3: sodium hydroxide / ethanol / 2 h / 50 °C
View Scheme
sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate
80382-23-6

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate

sodium 2-[4-[(2-oxocyclopentyl)methyl]phenyl]propanoate sesquihydrate

sodium 2-[4-[(2-oxocyclopentyl)methyl]phenyl]propanoate sesquihydrate

Conditions
ConditionsYield
Stage #1: sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate With pyrographite In ethanol; water; acetone at 55 - 65℃; for 0.5h;
Stage #2: In ethanol; water; acetone at 0 - 40℃; for 4h;
90.3%
sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate
80382-23-6

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate

Tolperisone hydrochloride

Tolperisone hydrochloride

loxoprofen tolperisone salt
1043449-71-3

loxoprofen tolperisone salt

Conditions
ConditionsYield
In isopropyl alcohol at 20℃; for 0.5h;
Conditions
ConditionsYield
With hydrogenchloride In water; toluene
sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate
80382-23-6

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate

loxoprofen methyl ester
81762-92-7

loxoprofen methyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: hydrogenchloride / water; toluene
2: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / 0 - 20 °C
View Scheme
sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate
80382-23-6

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate

methyl (+/-)-2-<4-(trans-2-hydroxycyclopentylmethyl)phenyl>propionate
89631-57-2, 89675-48-9, 90319-84-9, 90319-85-0, 90319-86-1, 90319-87-2

methyl (+/-)-2-<4-(trans-2-hydroxycyclopentylmethyl)phenyl>propionate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: hydrogenchloride / water; toluene
2: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / 0 - 20 °C
3: sodium tetrahydroborate / ethanol / 2 h / 0 °C
View Scheme
sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate
80382-23-6

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate

C25H42O3Si

C25H42O3Si

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: hydrogenchloride / water; toluene
2: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / 0 - 20 °C
3: sodium tetrahydroborate / ethanol / 2 h / 0 °C
4: 1H-imidazole / dichloromethane; N,N-dimethyl-formamide
View Scheme
sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate
80382-23-6

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate

C24H40O3Si

C24H40O3Si

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: hydrogenchloride / water; toluene
2: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / 0 - 20 °C
3: sodium tetrahydroborate / ethanol / 2 h / 0 °C
4: 1H-imidazole / dichloromethane; N,N-dimethyl-formamide
5: lithium hydroxide monohydrate / water; tetrahydrofuran; ethanol
View Scheme
sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate
80382-23-6

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate

C32H53F2NO5Si

C32H53F2NO5Si

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: hydrogenchloride / water; toluene
2: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / 0 - 20 °C
3: sodium tetrahydroborate / ethanol / 2 h / 0 °C
4: 1H-imidazole / dichloromethane; N,N-dimethyl-formamide
5: lithium hydroxide monohydrate / water; tetrahydrofuran; ethanol
6: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0 - 20 °C
View Scheme
1-bromoethyl acetate

1-bromoethyl acetate

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate
80382-23-6

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate

C19H24O5

C19H24O5

Conditions
ConditionsYield
With triethylamine In toluene
chloromethyl n-butyrate
33657-49-7

chloromethyl n-butyrate

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate
80382-23-6

sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate

C20H26O5

C20H26O5

Conditions
ConditionsYield
With triethylamine In toluene

Raw Materials

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