(R)-(-)-1-Phenyl-1,2-ethanediol supplier

Name
(R)-(-)-1-Phenyl-1,2-ethanediol
EINECS 202-258-1
CAS No. 16355-00-3
Article Data304
CAS DataBase
Density 1.17 g/cm³
Solubility Soluble in water
Melting Point 64-67 °C(lit.)
Formula C₈H₁₀O₂
Boiling Point 273.5 °C at 760 mmHg
Molecular Weight 138.166
Flash Point 145.8 °C
Transport Information
Appearance white to light yellow crystal powder
Safety 24/25-45-36/37/39-26
Risk Codes 23/24/25-36/37/38
Molecular Structure
Hazard Symbols Xi,T
Synonyms 1,2-Ethanediol, 1-phenyl-, (R)-(-)- (8CI);(-)-(1R)-1-Phenyl-1,2-ethanediol;(-)-1-Phenylethane-1,2-diol;(-)-1-Phenylethylene glycol;(-)-Phenyl glycol;(-)-Styrene glycol;(R)-(-)-1-Phenylethane-1,2-diol;(R)-2-Phenyl-1,2-ethanediol;1R-Phenyl-1,2-ethanediol;
PSA 40.46000
LogP 0.71230

Synthetic route

: 582-24-1
1-phenyl-2-hydroxyethanone

: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

Conditions

Conditions	Yield
With β-D-glucose In aq. phosphate buffer at 35℃; for 24h; pH=7.5; Kinetics; Temperature; pH-value; Solvent; Reagent/catalyst; Enzymatic reaction;	99.9%
With cobalt(II) acetate; C31H31N2OP In tetrahydrofuran at 25℃; for 1h; Reagent/catalyst; Inert atmosphere;	97%
With hydrogen; chiral iridium(III) complex In methanol at 60℃; under 7600.51 Torr; for 15h;	94%

: 1074-12-0
phenylglyoxal hydrate

: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

Conditions

Conditions	Yield
With D-glucose; D-glucose dehydrogenase; β-nicotinamide adenine dinucleotide 2'-phosphate reduced tetra(cyclohexylammonium) salt; carbonyl reductase from Pichia pastoris GS115; sodium hydroxide In aq. phosphate buffer; dimethyl sulfoxide at 20℃; for 12h; pH=6.5; Enzymatic reaction;	99%

: 292638-84-7
styrene

: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

Conditions

Conditions	Yield
With 1,4-bis(9-O-dihydroquinidine)phthalazine In water; tert-butyl alcohol at 20℃; for 2h; Sharpless asymmetric dihydroxylation;	98%
With potassium osmate(VI) dihydrate; cetyltrimethylammonim bromide; potassium carbonate; 1,4-bis(9-O-dihydroquinidine)phthalazine; potassium hexacyanoferrate(III) In water at 20℃; for 48h; Sharpless dihydroxylation; optical yield given as %ee;	98%
With water; potassium carbonate; (9S,9"S)-9,9"-[phthalazine-1,4-diylbis-(oxy)]bis[10,11-dihydro-6'-methoxycinchonane]; potassium hexacyanoferrate(III) In tert-butyl alcohol for 6h; Reagent/catalyst; enantioselective reaction;	98%

: 757195-36-1
(1R)-2-({[(1S)-2,2-dimethyl-1-phenylpropyl]amino}oxy)ethanol

A: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

B: 82729-98-4
(1S)-α-(1,1-dimethylethyl)benzenemethanamine

Conditions

Conditions	Yield
With hexacarbonyl molybdenum In water; acetonitrile at 85℃; for 1h;	A n/a B 98%

: 20698-91-3
(R)-methyl mandelate

: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

Conditions

Conditions	Yield
With sodium tetrahydroborate In methanol at 20℃; for 0.5h;	97%
With lithium aluminium tetrahydride	74%
Stage #1: (R)-methyl mandelate With lithium aluminium tetrahydride In 1,2-dimethoxyethane at 20℃; for 12h; Elimination; Stage #2: With hydrogenchloride; ammonium chloride Hydrolysis; Further stages.;	70%

: 96-09-3
styrene oxide

: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

Conditions

Conditions	Yield
With E. coli/(recombinant Vigna radiata epoxide hydrolase VrEH3) whole cells In methanol; aq. phosphate buffer at 25℃; for 7h; pH=7.0; pH-value; Temperature; Microbiological reaction; enantioselective reaction;	97%
With tris paraperiodate; water In acetonitrile for 0.0833333h; Ambient temperature;	90%
With epoxide hydrolase from Vigna radiata; variant VrEH2M263V In aq. phosphate buffer; dimethyl sulfoxide at 30℃; for 1.5h; pH=7; Reagent/catalyst; Enzymatic reaction; enantioselective reaction;	90%

: 292638-84-7
styrene

A: 96-09-3
styrene oxide

B: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

C: 25779-13-9
(S)-1-phenyl-1,2-ethanediol

Conditions

Conditions	Yield
With styrene monooxygenase In Hexadecane for 24h; aq. buffer; optical yield given as %ee;	A 97% B n/a C n/a

...Expand

: 96-09-3
styrene oxide

A: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

B: 20780-54-5
(S)-styrene oxide

Conditions

Conditions	Yield
Stage #1: styrene oxide With water; 4-nitro-benzoic acid; [(S,S)-N,N’-bis(3,5-di-tertbutylsalicylidene)-1,2-cyclohexanediaminato(2-)]cobalt(II) at 20℃; Acidic aqueous solution; Stage #2: With ammonia at 20℃; for 1h;	A 95.3% B 67.9%
With Aspergillus niger epoxide hydrolases immobilized onto modified Eupergit C In aq. phosphate buffer; dimethyl sulfoxide at 25℃; for 4h; pH=6.5; Kinetics; Reagent/catalyst; Enzymatic reaction; enantioselective reaction;	A n/a B 48%
With [(S,S)-N,N’-bis(3,5-di-tertbutylsalicylidene)-1,2-cyclohexanediaminato(2-)]cobalt(II); water In dichloromethane; acetonitrile at 20℃; for 144h; Resolution of racemate;	A n/a B 47%

: 582-24-1
1-phenyl-2-hydroxyethanone

A: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

B: 25779-13-9
(S)-1-phenyl-1,2-ethanediol

Conditions

Conditions	Yield
With cobalt(II) acetate; C31H31N2OP In tetrahydrofuran at 25℃; for 1h; Reagent/catalyst; Inert atmosphere;	A 95% B n/a
With diisobutylaluminium hydride; (S)-1-methyl-2-<(piperidin-1-yl)-methyl>pyrrolidine; tin(ll) chloride In dichloromethane at -100℃; for 0.333333h; Product distribution; asymmetric reduction of prochiral hydroxy ketones;
With baker yeast Product distribution; Thermodynamic data; ee = 99.19percent, ΔΔG(excit.)298 = 3.26+/-0.06 kcal/mol;

: 147256-18-6
(R)-2-hydroxy-2-phenylethyl acetate

: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

Conditions

Conditions	Yield
With potassium carbonate In methanol for 4h;	95%
With potassium carbonate In methanol for 4h;	94%

: 757195-42-9
(1R)-2-{[(S)-[(2-(methoxymethoxy)phenyl)(phenyl)methyl]amino]oxy}-1-phenylethanol

A: (1S)-1-[2-(methoxymethoxy)phenyl](phenyl)methanamine

B: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

Conditions

Conditions	Yield
With hexacarbonyl molybdenum In water; acetonitrile at 85℃; for 1h;	A 95% B n/a

: 292638-84-7
styrene

Resin-OsO4: Resin-OsO4

: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

Conditions

Conditions	Yield
	94%
	94%
	94%

: 96-09-3
styrene oxide

A: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

B: 25779-13-9
(S)-1-phenyl-1,2-ethanediol

Conditions

Conditions	Yield
With Escherichia coli Rosetta(DE3)/epoxide hydrolase from Glycine max wet cells In aq. phosphate buffer at 25℃; pH=7; Catalytic behavior; Microbiological reaction; Resolution of racemate; Enzymatic reaction; enantioselective reaction;	A 93.8% B n/a
With water at 37℃; rabbit liver microsomal epoxide hydrolase; Yields of byproduct given. Title compound not separated from byproducts;
With water In ethanol Beauveria sulfurescens; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

: 147441-61-0
(R)-2,2-dimethyl-4-phenyl-1,3-dioxolane

: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

Conditions

Conditions	Yield
zirconium(IV) chloride In methanol at 35℃; for 3h;	93%

: 1041400-13-8
(R)-(-)-2-tert-butoxy-2-oxo-1-phenylethyl pyrrolidine-1-carboxylate

: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

Conditions

Conditions	Yield
With lithium aluminium tetrahydride In tetrahydrofuran at -78 - 20℃; Inert atmosphere;	92%

: 1258406-85-7
(2S,5R)-2-(2-chlorophenyl)-5-phenyl-3-tosyloxazolidin-4-one

: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

Conditions

Conditions	Yield
With lithium aluminium tetrahydride In tetrahydrofuran at 0℃; Inert atmosphere;	92%

: 757195-48-5
(1R)-2-[({(1S)-1-[2-(methoxymethoxy)phenyl]ethyl}amino)oxy]-1-phenylethanol

A: 757195-50-9
(1S)-1-[2-(methoxymethoxy)phenyl]ethanamine

B: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

Conditions

Conditions	Yield
With hexacarbonyl molybdenum In water; acetonitrile at 85℃; for 1h;	A 91% B n/a

: 144688-34-6
(R)-(-)-1-phenylethane-1,2-diol dipropionate

: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

Conditions

Conditions	Yield
With sodium hydroxide In methanol at 25℃; for 3h;	90%

: 78692-90-7
(R)-2-methylcarbonyloxy-1-phenylethyl acetate

: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

Conditions

Conditions	Yield
zirconium(IV) chloride In methanol at 35℃; for 4h;	90%
With potassium carbonate In methanol at 20℃; for 4h;

: 1067232-57-8
(4S,1'R,2'R)-N-(3)-[1'-(m-chlorobenzoyl)-2-hydroxy-2'-phenylethan-1'yl]-4-phenyl-5,5-dimethyloxazolidin-2-one

A: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

B: 168297-84-5
(4S)-5,5-dimethyl-4-phenyl-1,3-oxazolidin-2-one

Conditions

Conditions	Yield
With sodium tetrahydroborate In methanol for 0.166667h;	A 60% B 90%

: 292638-84-7
styrene

A: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

B: 25779-13-9
(S)-1-phenyl-1,2-ethanediol

Conditions

Conditions	Yield
With potassium dioxotetrahydroxoosmate(VI); potassium carbonate; potassium hexacyanoferrate(III); methanesulfonamide; DHQD-PHAL-OPEG-OMe In water; tert-butyl alcohol at 0℃; for 24h; Title compound not separated from byproducts;	A 87% B n/a
With osmium(VIII) oxide; lithium aluminium tetrahydride; MEQ-DHQD Thermodynamic data; Kinetics; 1) toluene, 2) THF, 30 min, RT; influence of the reaction temperature on the enantioselectivity of the asymmetric dihydroxylation of different olefins with other reagents, investigations of the ee-values;
With potassium dioxotetrahydroxoosmate(VI); iodine; potassium carbonate; 1,4-bis(9-O-dihydroquinidine)phthalazine In water; tert-butyl alcohol at 0℃; for 27h; Product distribution; Mechanism; electrolysis; various co-oxidants; asymmetric dihydroxylation; further cond.: chemical method;

: 20780-53-4
(R)-Styrene oxide

A: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

B: 25779-13-9
(S)-1-phenyl-1,2-ethanediol

Conditions

Conditions	Yield
With Tris-HCl buffer; Sphingomonas sp. HXN-200 cell free extract In hexane at 25℃; for 4h; pH=7.5; Title compound not separated from byproducts;	A 87% B 13%
With water; potassium hydroxide at 30℃; for 288h; Product distribution; Mechanism; other pH;
With sodium phosphate buffer; enzymatic extract of S. racemosum In dimethyl sulfoxide at 27℃; Rate constant; Mechanism; Product distribution; regioselectivity of the biohydrolysis;

: 173603-23-1
(E)-2,2′-(1-phenylethene-1,2-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane)

: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

Conditions

Conditions	Yield
Stage #1: (E)-2,2′-(1-phenylethene-1,2-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) With hydrogen; di(norbornadiene)rhodium(I) tetrafluoroborate; (R)-1-[2-(2'-diphenylphosphinophenyl)-ferrocenyl]ethyldi[bis-(3,5-trifluoromethyl)phenyl]phosphine under 11400.8 Torr; Stage #2: With dihydrogen peroxide Product distribution / selectivity;	86%
Stage #1: (E)-2,2′-(1-phenylethene-1,2-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) With hydrogen; di(norbornadiene)rhodium(I) tetrafluoroborate; (R)-1-[2-(2'-diphenylphosphinophenyl)-ferrocenyl]ethyldi[bis-(3,5-trifluoromethyl)phenyl]phosphine under 11400.8 Torr; Stage #2: With sodium hydroxide; dihydrogen peroxide Product distribution / selectivity;	86%

: 4427-92-3
4-Phenyl-1,3-dioxolan-2-one

A: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

B: 4427-92-3, 90971-11-2, 129097-94-5, 90970-80-2
(4S)-4-phenyl[1,3]dioxolan-2-one

Conditions

Conditions	Yield
In dimethyl sulfoxide at 20℃; Kinetics; pig liver esterase, phosphate buffer pH 7.4;	A 85% B n/a
In dimethyl sulfoxide at 20℃; pig liver esterase, phosphate buffer pH 7.4; Yields of byproduct given;	A 85% B n/a

: 611-71-2
(R)-Mandelic Acid

: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

Conditions

Conditions	Yield
With lithium aluminium tetrahydride In diethyl ether 1.) reflux, 5 h, 2.) RT, 12 h;	85%
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 20℃; for 2.5h; Inert atmosphere;	71%
With lithium aluminium tetrahydride In diethyl ether for 6h; Reduction; Heating;	70%

: 757195-34-9
(1R)-1-phenyl-2-({[(1S)-1-phenylpentyl]amino}oxy)ethanol

A: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

B: 105370-60-3
(1S)-1-amino-1-phenylpentane

Conditions

Conditions	Yield
With hexacarbonyl molybdenum In water; acetonitrile at 85℃; for 1h;	A n/a B 85%

: 757195-40-7
(1R)-1-phenyl-2-({[(1S)-1-phenyl-2-propenyl]amino}oxy)ethanol

A: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

B: 244092-75-9
(1S)-1-phenyl-2-propen-1-amine

Conditions

Conditions	Yield
With zinc In tetrahydrofuran; water; acetic acid at 60℃; for 4h;	A n/a B 83%

: 757195-26-9
(1R)-1-phenyl-2-({[(1S)-1-phenylethyl]amino}oxy)ethanol

A: 2627-86-3
(S)-1-phenyl-ethylamine

B: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

Conditions

Conditions	Yield
With hexacarbonyl molybdenum In water; acetonitrile at 85℃; for 1h;	A 80% B n/a

: 179924-50-6
(R)-1-phenyl-2-(α,α-diphenylbenzyloxy)ethyl-3,4-di-O-benzyl-2-deoxy-6-O-(α,α-diphenylbenzyl)-L-glucoside

A: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

B: 3,4-di-O-benzyl-2-deoxy-L-glucopyranose

Conditions

Conditions	Yield
In tetrahydrofuran; hydrogenchloride Hydrolysis;	A 2.37 g B 78%

: 93-56-1
phenylethane 1,2-diol

A: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

B: 25779-13-9
(S)-1-phenyl-1,2-ethanediol

Conditions

Conditions	Yield
With cell free extract from Candida parapsilosis CICC 1627 In aq. phosphate buffer at 30℃; for 48h; pH=6.5; Reagent/catalyst; Microbiological reaction; enantioselective reaction;	A n/a B 78%
With MCCD-HPS packed column In hydrogenchloride; acetonitrile pH=8.6;
With halohydrin dehydro-dehalogenase from Alcaligenes sp. DS-S-7G; 2,6-Dichlorophenolindophenol; phenazine methosulfate Enzymatic reaction; Title compound not separated from byproducts.;

: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

: 133522-24-4
(R)-4-Phenyl-[1,3,2]dioxathiolane 2-oxide

Conditions

Conditions	Yield
With thionyl chloride In tetrachloromethane Heating;	100%
With thionyl chloride Heating;	79%
With thionyl chloride In dichloromethane Yield given;

: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

: 18162-48-6
tert-butyldimethylsilyl chloride

: 110743-96-9
(R)-2-(tert-butyldimethylsilyloxy)-1-phenylethan-1-ol

Conditions

Conditions	Yield
With 1H-imidazole In dichloromethane at 0 - 20℃; for 1.5h; Inert atmosphere;	100%
With dmap; triethylamine In dichloromethane for 4h; Inert atmosphere;	98%
With dmap; triethylamine In dichloromethane at 20℃; for 2h;	91%
With dmap; triethylamine In dichloromethane at 20℃; for 2h;	87%

: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

: 124-63-0
methanesulfonyl chloride

: 278169-72-5
(R)-phenyl-1,2-bis(methanesulfonyloxy)ethane

Conditions

Conditions	Yield
With triethylamine In dichloromethane	100%
With triethylamine In dichloromethane at 0 - 20℃;
With triethylamine In dichloromethane
Stage #1: (R)-1-phenyl-1,2-ethanediol With triethylamine In dichloromethane at 0℃; for 0.166667h; Stage #2: methanesulfonyl chloride In dichloromethane at 20℃; for 5h;

: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

: 39637-99-5, 20445-33-4
(S)-(+)-2-methoxy-2-trifluoromethyl-2-phenylacetyl chloride

: (R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (R)-1-phenyl-2-((R)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionyloxy)-ethyl ester

Conditions

Conditions	Yield
With pyridine In dichloromethane at 20℃; for 18h;	99%
With pyridine; 1-amino-3-(dimethylamino)propane In dichloromethane for 0.416667h;

: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

: 17261-28-8
ortho-diphenylphosphinobenzoic acid

: 1220999-80-3
(R)-2-hydroxy-2-phenylethyl 2-(diphenylphosphino)-benzoate

Conditions

Conditions	Yield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane for 24h; Inert atmosphere;	98%

: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

: 611-71-2
(R)-Mandelic Acid

Conditions

Conditions	Yield
With sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; potassium bromide In acetone at 0℃; pH=8.3; chemoselective reaction;	96%
With recombinant alditol oxidase from Streptomyces coelicolor A3(2); catalase from bovine liver at 25℃; pH=7.5; Kinetics; Reagent/catalyst; Temperature; pH-value; aq. phosphate buffer; Enzymatic reaction; enantioselective reaction;

: 124-38-9
carbon dioxide

: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

: 90971-11-2
(R)-1-phenyl-1,2-ethanediol carbonate

Conditions

Conditions	Yield
With 1-butyl-3-methylimidazolium hexafluorophosphate; 1,8-diazabicyclo[5.4.0]undec-7-ene at 70℃; under 7500.75 Torr; for 18h;	96%

: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

: 98-59-9
p-toluenesulfonyl chloride

: 40434-87-5
(R)-2-hydroxy-2-phenylethyl 4-methylbenzenesulfonate

Conditions

Conditions	Yield
With di(n-butyl)tin oxide; triethylamine In dichloromethane at 0 - 20℃; for 3h;	92.2%
With pyridine at 0 - 20℃; Inert atmosphere;	78%
With pyridine at -10℃; for 4h;	76%

: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

: 144-79-6
chloromethyldiphenylsilane

: 1,2-bis(diphenylmethylsilyloxy)-1-phenylethane

Conditions

Conditions	Yield
With dmap; triethylamine In dichloromethane at 20℃; for 3h; Inert atmosphere;	90%

: 16355-00-3
(R)-1-phenyl-1,2-ethanediol

: 5122-94-1
4-biphenylboronic acid

: (R)-(-)-2-(4-biphenyl)-4-phenyl-1,3,2-dioxaborolane

Conditions

Conditions	Yield
In chloroform at 20℃;	89%
With 4 A molecular sieve In chloroform at 20℃;	89%

(R)-(-)-1-Phenyl-1,2-ethanediol Chemical Properties

Structure of (R)-(-)-1-Phenyl-1,2-ethanediol (CAS NO.16355-00-3):

IUPAC Name: (1S)-1-Phenylethane-1,2-diol
Molecular Formula: C₈H₁₀O₂
Molar mass: 138.1638 g/mol
Density: 1.17 g/cm³
Melting Point: 64-67 °C(lit.)
Flash Point: 145.8 °C
Index of Refraction: 1.572
Boiling Point: 273.5 °C at 760 mmHg
Vapour Pressure: 0.00278 mmHg at 25 °C
Water Solubility: soluble
Appearance: white to light yellow crystal powder
XLogP3-AA: 0.4
H-Bond Donor: 2
H-Bond Acceptor: 2
Canonical SMILES: C1=CC=C(C=C1)C(CO)O
Isomeric SMILES: C1=CC=C(C=C1)[C@@H](CO)O
InChI: InChI=1S/C8H10O2/c9-6-8(10)7-4-2-1-3-5-7/h1-5,8-10H,6H2/t8-/m1/s1
InChIKey: PWMWNFMRSKOCEY-MRVPVSSYSA-N
Product categories: Chiral Compounds; Diols; Chiral Building Blocks; Synthetic Organic Chemistry; Simple Alcohols (Chiral)

(R)-(-)-1-Phenyl-1,2-ethanediol Safety Profile

Hazard Codes: Irritant Xi, Toxic T
Risk Statements: 23/24/25-36/37/38
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 24/25-45-36/37/39-26
S24/25:Avoid contact with skin and eyes.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
WGK Germany: 3
Hazard Note: Irritant

(R)-(-)-1-Phenyl-1,2-ethanediol Specification

(R)-(-)-1-Phenyl-1,2-ethanediol (CAS NO.16355-00-3) also can be called (1R)-1-phenylethane-1,2-diol ; (R)-(-)-alpha,beta-Dihydroxyethylbenzene ; (R)-(-)-Stryrene glycol and 1,2-ethanediol, 1-phenyl-, (1R)- . It is hazardous, so the first aid measures and others should be known. Such as: When on the skin: first,should flush skin with plenty of water immediately for at least 15 minutes while removing contaminated clothing. Secondly, Get medical aid. Or in the eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Then get medical aid soon. While, it's Inhaled: Remove from exposure and move to fresh air immediately. Give artificial respiration while not breathing. When breathing is difficult, give oxygen. And as soon as to get medical aid. Then you have the ingesting of the product : Do not induce vomiting.If victim is conscious and alert, give 2-4 cupfuls of milk or water, and get medical aid immediately. In addition, (R)-(-)-1-Phenyl-1,2-ethanediol (CAS NO.16355-00-3) can be stable under normal temperature and pressure conditions. You must not take it with strong oxidants. And also prevent it to broken down into hazardous decomposition products: irritating and toxic fumes and gases.

Product Name

(R)-(-)-1-Phenyl-1,2-ethanediol

Synthetic route

(R)-(-)-1-Phenyl-1,2-ethanediol Chemical Properties

(R)-(-)-1-Phenyl-1,2-ethanediol Safety Profile

(R)-(-)-1-Phenyl-1,2-ethanediol Specification

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