1,1,2-Trichlorotrifluoroethane supplier

Name
1,1,2-Trichlorotrifluoroethane
EINECS 200-936-1
CAS No. 76-13-1
Article Data75
CAS DataBase
Density 1.67 g/cm³
Solubility insoluble in water
Melting Point -35 °C(lit.)
Formula C₂Cl₃F₃
Boiling Point 50.9 °C at 760 mmHg
Molecular Weight 187.376
Flash Point 195°C
Transport Information UN 3082 9/PG 3
Appearance Colorless liquid with a sweet, ether-like odor
Safety 59-61-45-36/37
Risk Codes 52/53-59-39/23/24/25
Molecular Structure
Hazard Symbols N,Xi,T
Synonyms 1,1,2-Trichloro-1,2,2-trifluoroethane;Arcton 113;Arklone P;Asahifron 113;CFC 113;Daiflon 113;Delifrene 113;Delifrene LS;FC 113;FKW 113;Fluorocarbon 113;Forane 113;Freon 113;Freon 113TR-T;Freon TF;Freon TS;Fridohna;Frigen 113;Frigen 113A;Frigen 113TR-N;Fron 113;Fronsolve113;Genetron 113;Halon 113;Isceon 113;Khladon 113;Ledon113;R 113;Refrigerant 113;Refrigerant R 113;
PSA 0.00000
LogP 2.91890

Synthetic route

: 67-72-1
hexachloroethane

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

Conditions

Conditions	Yield
With aluminum(III) fluoride; hydrogen fluoride at 120℃; under 11251.1 Torr; for 10h; Reagent/catalyst; Temperature; Autoclave;	97.06%
With CFC-112a; antimonypentachloride; fluorine at 32℃; unter vermindertem Druck;
With antimonypentachloride; antimony(III) fluoride at 48℃;

: 7740-58-1
1,2,2-trifluorodichloroethanesulfonyl chloride

A: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

B: 7446-09-5
sulfur dioxide

Conditions

Conditions	Yield
200°C, 7 days;	A 97% B 97%
100°C, 7 days;	A 19% B 18%

: 79-38-9
Chlorotrifluoroethylene

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

Conditions

Conditions	Yield
With benzophenone; chlorine at -80℃;	92%

: 76-12-0
CFC-112a

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

Conditions

Conditions	Yield
With bromine trifluoride; antimonypentachloride In 1,1,2-Trichloro-1,2,2-trifluoroethane at 20 - 25℃;	90%
With chromium(III) oxyfluoride; hydrogen fluoride at 500℃;

: 79-38-9
Chlorotrifluoroethylene

: 53268-50-1
chloro(trifluoromethyl)disulfane

A: 55882-11-6
2,2-dichlorotrifluoroethyl(trifluoromethyl)disulfane

B: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

C: 372-07-6
bis(trifluoromethyl)tetrasulfide

D: 55882-10-5
1,2-dichlorotrifluoroethyl(trifluoromethyl)disulfane

Conditions

Conditions	Yield
Irradiation (UV/VIS);	A n/a B n/a C n/a D 80%
Irradiation (UV/VIS);	A n/a B n/a C n/a D 80%

...Expand

: 695-50-1
1,2-dichlorotetrafluorocyclopropane

A: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

B: 1,3-dichloro-1,2,2,3-tetrafluoro-1,3-diiodo-propane

Conditions

Conditions	Yield
With iodine at 140 - 165℃; for 4h;	A n/a B 63%

: 79-01-6
Trichloroethylene

A: 354-15-4
1,2,2-trichloro-1,2-difluoroethane

B: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

Conditions

Conditions	Yield
With hydrogen fluoride; fluorine In trichlorofluoromethane at -70℃; for 4h; Product distribution / selectivity; Inert atmosphere;	A 50% B 18%

: 79-38-9
Chlorotrifluoroethylene

: 1768-32-7
sulfur bis(trifluoromethyl)amide chloride

A: 34994-73-5
2,4-dichlorohexafluorothiolane

B: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

C: 81619-76-3
N,N-bistrifluoromethyl-2,2-dichlorotrifluoroethanesulfenamide

D: S-(1,2-Dichloro-1,2,2-trifluoro-ethyl)-N,N-bis-trifluoromethyl-thiohydroxylamine

Conditions

Conditions	Yield
for 528h; Irradiation; Further byproducts given;	A 11% B 16% C 31% D 31%

...Expand

: 79-38-9
Chlorotrifluoroethylene

: 1768-32-7
sulfur bis(trifluoromethyl)amide chloride

A: 423-38-1
1,1,3,4-Tetrachlorohexafluorobutane

B: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

C: 81619-76-3
N,N-bistrifluoromethyl-2,2-dichlorotrifluoroethanesulfenamide

D: S-(1,2-Dichloro-1,2,2-trifluoro-ethyl)-N,N-bis-trifluoromethyl-thiohydroxylamine

Conditions

Conditions	Yield
for 528h; Irradiation; Further byproducts given;	A 6.5% B 16% C 31% D 31%

...Expand

: 79-38-9
Chlorotrifluoroethylene

: 1768-32-7
sulfur bis(trifluoromethyl)amide chloride

A: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

B: 1913-85-5
sulfur bis{bis(trifluoromethyl)amide}

C: 81619-76-3
N,N-bistrifluoromethyl-2,2-dichlorotrifluoroethanesulfenamide

D: S-(1,2-Dichloro-1,2,2-trifluoro-ethyl)-N,N-bis-trifluoromethyl-thiohydroxylamine

Conditions

Conditions	Yield
for 528h; Irradiation; Further byproducts given;	A 16% B 15% C 31% D 31%

...Expand

: 79-38-9
Chlorotrifluoroethylene

: 1768-32-7
sulfur bis(trifluoromethyl)amide chloride

A: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

B: 81619-76-3
N,N-bistrifluoromethyl-2,2-dichlorotrifluoroethanesulfenamide

C: S-(1,2-Dichloro-1,2,2-trifluoro-ethyl)-N,N-bis-trifluoromethyl-thiohydroxylamine

D: S-[2-(Bis-trifluoromethyl-amino)-1-chloro-1,2,2-trifluoro-ethyl]-N,N-bis-trifluoromethyl-thiohydroxylamine

Conditions

Conditions	Yield
for 528h; Irradiation; Further byproducts given;	A 16% B 31% C 31% D 4%

...Expand

: 79-38-9
Chlorotrifluoroethylene

: 1768-32-7
sulfur bis(trifluoromethyl)amide chloride

A: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

B: 2714-58-1
disulfur bis{bis(trifluoromethyl)amide}

C: 81619-76-3
N,N-bistrifluoromethyl-2,2-dichlorotrifluoroethanesulfenamide

D: S-(1,2-Dichloro-1,2,2-trifluoro-ethyl)-N,N-bis-trifluoromethyl-thiohydroxylamine

Conditions

Conditions	Yield
for 528h; Irradiation; Further byproducts given;	A 11% B 12% C 26% D 26%

...Expand

: 79-38-9
Chlorotrifluoroethylene

: 93460-12-9
α-chlorocarbonylhexafluoroisopropylsulfenyl chloride

A: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

B: 83235-80-7
bis-(α-chlorocarbonylhexafluoroisopropyl) disulfide

C: 2,2-dichlorotrifluoroethyl 1-chlorocarbonylhexafluoroisopropyl sulfide

Conditions

Conditions	Yield
at 150 - 160℃; for 10h;	A n/a B n/a C 21%

...Expand

: 127-18-4
1,1,2,2-tetrachloroethylene

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

Conditions

Conditions	Yield
With hydrogen fluoride; antimonypentachloride at 75 - 100℃;
With antimony (III)-antimony (V)-fluoro chloride ene; hydrogen fluoride; chlorine at 160 - 165℃; unter Druck;
With zirconium(IV) fluoride; hydrogen fluoride at 350 - 360℃;

: 76-11-9
1,1-difluorotetrachloroethane

A: 354-58-5
1,1,1-Trichloro-2,2,2-trifluoroethane

B: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

Conditions

Conditions	Yield
With hydrogen fluoride; pyrographite; lithium fluoride at 375 - 550℃;

: 630-20-6
1,1,1,2-tetrachoroethane

A: 76-14-2
1,2-dichloro-1,1,2,2-tetrafluoroethane

B: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

Conditions

Conditions	Yield
With antimony (III)-antimony (V)-fluoro chloride; hydrogen fluoride; chlorine at 160 - 165℃; unter Druck;
With antimony (III)-antimony (V)-fluoro chloride; hydrogen fluoride; chlorine at 160 - 165℃; unter Druck;
With antimony (III)-antimony (V)-fluoro chloride; hydrogen fluoride; chlorine at 160 - 165℃; unter Druck;

: 354-12-1
1,1,1-trichloro-2,2-difluoroethane

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

Conditions

Conditions	Yield
With hydrogen fluoride; antimonypentachloride at 125℃;

: 79-01-6
Trichloroethylene

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

Conditions

Conditions	Yield
With nitrogen; copper; fluorine at 70℃;

: 354-11-0
F121a

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

Conditions

Conditions	Yield
With hydrogen fluoride; antimonypentachloride at 125℃;

: 67-72-1
hexachloroethane

A: 76-14-2
1,2-dichloro-1,1,2,2-tetrafluoroethane

B: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

Conditions

Conditions	Yield
With antimony (III)-antimony (V)-fluoro chloride; hydrogen fluoride; chlorine at 160 - 165℃; unter Druck;
With antimony (III)-antimony (V)-fluoro chloride; hydrogen fluoride; chlorine at 160 - 165℃; unter Druck;
With antimony (III)-antimony (V)-fluoro chloride; hydrogen fluoride; chlorine at 160 - 165℃; unter Druck;

: 598-88-9
1,2-dichloro-1,2-difluoroethene

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

Conditions

Conditions	Yield
With fluorine at 0℃;
With sulfur tetrafluoride; hydrogen fluoride; chlorine at 20℃; for 10h; Yield given;

: 79-01-6
Trichloroethylene

A: 354-23-4
1,2-dichloro-1,2,2-trifluoroethane

B: 812-04-4
1,1-dichloro-1,2,2-trifluoroethane

C: 354-15-4
1,2,2-trichloro-1,2-difluoroethane

D: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

Conditions

Conditions	Yield
With manganese(III) fluoride at 120℃;
With manganese(III) fluoride at 220℃;

...Expand

: 79-01-6
Trichloroethylene

A: 354-23-4
1,2-dichloro-1,2,2-trifluoroethane

B: 354-15-4
1,2,2-trichloro-1,2-difluoroethane

C: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

D: 76-12-0
CFC-112a

Conditions

Conditions	Yield
With cobalt (III) fluoride at 120℃; Further byproducts given;

...Expand

: 79-01-6
Trichloroethylene

A: 75-88-7
1,1,1-trifluoro-2-chloroethane

B: 354-15-4
1,2,2-trichloro-1,2-difluoroethane

C: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

D: 76-12-0
CFC-112a

Conditions

Conditions	Yield
With cobalt (III) fluoride at 120℃; Further byproducts given;

...Expand

: 79-01-6
Trichloroethylene

A: 812-04-4
1,1-dichloro-1,2,2-trifluoroethane

B: 354-15-4
1,2,2-trichloro-1,2-difluoroethane

C: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

D: 76-12-0
CFC-112a

Conditions

Conditions	Yield
With cobalt (III) fluoride at 120℃; Further byproducts given;

...Expand

: 79-38-9
Chlorotrifluoroethylene

A: 425-11-6
1,2-Dinitro-1-chlortrifluoraethan

B: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

C: 354-27-8
chlorodifluoroacetyl fluoride

D: 354-71-2
1,2-dichloro-1,2,2-trifluoronitrosoethane

Conditions

Conditions	Yield
With nitrogen(II) oxide; iron(III) chloride Further byproducts given;

...Expand

: 79-38-9
Chlorotrifluoroethylene

A: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

B: 354-61-0
1,2-dichloro-1,2,2-trifluoro-1-iodoethane

C: 661-66-5
1,1-Dichloro-2-iodotrifluoroethane

Conditions

Conditions	Yield
With Iodine monochloride

...Expand

: 79-38-9
Chlorotrifluoroethylene

A: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

B: 354-27-8
chlorodifluoroacetyl fluoride

C: 354-71-2
1,2-dichloro-1,2,2-trifluoronitrosoethane

Conditions

Conditions	Yield
With nitrogen(II) oxide; iron(III) chloride

...Expand

: 79-38-9
Chlorotrifluoroethylene

A: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

B: 354-27-8
chlorodifluoroacetyl fluoride

C: 354-71-2
1,2-dichloro-1,2,2-trifluoronitrosoethane

D: 1717-62-0
2-nitro-1,1-dichlorotrifluoroethane

Conditions

Conditions	Yield
With nitrogen(II) oxide; iron(III) chloride Further byproducts given;

...Expand

: 79-38-9
Chlorotrifluoroethylene

A: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

B: 354-27-8
chlorodifluoroacetyl fluoride

C: 354-71-2
1,2-dichloro-1,2,2-trifluoronitrosoethane

D: 755-62-4
1-chloro-1,2,2-trifluoro-2-nitro-1-nitroso-ethane

Conditions

Conditions	Yield
With nitrogen(II) oxide; iron(III) chloride Further byproducts given;

...Expand

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

: 79-38-9
Chlorotrifluoroethylene

Conditions

Conditions	Yield
With potassium zinc trihydride at 250 - 320℃; under 7500.75 Torr; for 5h; Temperature; Pressure; Inert atmosphere; Large scale;	99.22%
With ammonium chloride; zinc(II) chloride In methanol; water electrochemical process;	90%
With zinc(II) chloride; zinc In ethanol at 50℃; for 3h; Dehalogenation;	75%

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

: 360-53-2
1,3,3,3-tetrafluoro-1-methoxy-2-trifluoromethyl-propene

: C6H3F9O

Conditions

Conditions	Yield
at 120℃; for 2.5h;	98%

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

: 109-77-3
malononitrile

: 71160-05-9
dimethyl 1,3-propanediimidate dihydrochloride

Conditions

Conditions	Yield
In hydrogenchloride; methanol	96%

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

A: 354-23-4
1,2-dichloro-1,2,2-trifluoroethane

B: 79-38-9
Chlorotrifluoroethylene

C: 359-11-5
1,1,2-trifluoroethylene

Conditions

Conditions	Yield
With hydrogen; silica gel; nickel at 450℃; under 760 Torr; Title compound not separated from byproducts;	A n/a B 95.8% C n/a
bismuth(III) chloride; silica gel; palladium at 250℃; Yield given. Yields of byproduct given;
With hydrogen; silica gel; nickel at 450℃; under 760 Torr; Product distribution; other supported Ni catalysts and metal oxides;
bismuth(III) chloride; silica gel; palladium at 250℃; under 760 Torr; Product distribution; other catalysts and modifier; variation of condition: selectivity;

...Expand

: 592-76-7
1-Heptene

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

: 129277-71-0
1,1-Dichloro-1,2,2-trifluoro-nonane

Conditions

Conditions	Yield
With ammonium peroxydisulfate; sodium formate In N,N-dimethyl-formamide at 40℃; for 4h;	88.5%

: 592-41-6
1-hexene

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

: 129277-70-9
1,1-Dichloro-1,2,2-trifluoro-octane

Conditions

Conditions	Yield
With ammonium peroxydisulfate; sodium formate In N,N-dimethyl-formamide at 40℃; for 3h; other alkenes and alkynes;	86.5%
With ammonium peroxydisulfate; sodium formate In N,N-dimethyl-formamide at 40℃; for 3h;	86.5%

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

: 930-69-8
sodium thiophenolate

A: 91122-75-7
2-chloro-1,1,2-trifluoro-1-(phenyl thio) ethane

B: 91122-73-5
<(2,2-dichloro-1,1,2-trifluoroethyl)thio>benzene

C: 882-33-7
diphenyldisulfane

Conditions

Conditions	Yield
In dimethyl sulfoxide for 0.5h; Product distribution; Mechanism; Ambient temperature; various per(chloro,fluoro)ethanes and conditions;	A 0.9 % Chromat. B 86% C 3 % Chromat.
In dimethyl sulfoxide for 0.5h; Ambient temperature;	A 0.9 % Chromat. B 86% C 3 % Chromat.
In water; dimethyl sulfoxide for 48h; Ambient temperature;	A 18 % Chromat. B 16 % Chromat. C 38 % Chromat.

...Expand

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

: 86-74-8
9H-carbazole

: 1-(2,2-dichlorotrifluoroethyl)carbazole

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 30 - 35℃; for 0.833333h;	84%

: 120-72-9
indole

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

: 1-(2,2-dichlorotrifluoroethyl)indole

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 40 - 45℃; for 0.5h;	81%

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

: 122-39-4
diphenylamine

: N-(2,2-dichlorotrifluoroethyl)diphenylamine

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 45 - 50℃; for 0.5h;	81%

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

: 354-23-4
1,2-dichloro-1,2,2-trifluoroethane

Conditions

Conditions	Yield
With ammonium persulfate; ammonium formate In N,N-dimethyl-formamide at 30 - 40℃;	80%
With ammonium persulfate; ammonium formate In N,N-dimethyl-formamide at 30 - 40℃; Product distribution; Mechanism; also with further polyhalofluoroalkanes;	80%
Irradiation;
With water; sodium formate; titanium(IV) oxide Mechanism; Ambient temperature; Irradiation;

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

: 110-83-8
cyclohexene

: 129298-65-3
(2,2-Dichloro-1,1,2-trifluoro-ethyl)-cyclohexane

Conditions

Conditions	Yield
With ammonium peroxydisulfate; sodium formate In N,N-dimethyl-formamide at 50℃; for 8h;	79.5%

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

: 100-67-4
potassium phenolate

A: 456-62-2
1-hydro-1-chloro-2-phenoxyperfluoroethane

B: 95519-55-4
<(2,2-dichloro-1,1,2-trifluoroethyl)oxy>benzene

Conditions

Conditions	Yield
In dimethyl sulfoxide for 1h; Ambient temperature; Yields of byproduct given;	A n/a B 79%
In dimethyl sulfoxide for 4h;	A 9% B 37%

...Expand

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

: 591-87-7
Allyl acetate

: 129277-72-1
Acetic acid 5,5-dichloro-4,4,5-trifluoro-pentyl ester

Conditions

Conditions	Yield
With ammonium peroxydisulfate; sodium formate In N,N-dimethyl-formamide at 40℃; for 2h;	78.4%

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

A: 76-16-4
Hexafluoroethane

B: 76-15-3
Chloropentafluoroethane

C: 76-14-2
1,2-dichloro-1,1,2,2-tetrafluoroethane

Conditions

Conditions	Yield
With chromium fluoride; magnesium fluoride; hydrogen fluoride at 250 - 500℃; Product distribution;	A 3% B 78% C 19%

...Expand

: 92-84-2
10H-phenothiazine

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

: 1-(2,2-dichlorotrifluoroethyl)phenthiazine

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 40 - 45℃; for 0.666667h;	78%

: 5909-26-2
2,4-Bis(methylthio)pyrimidine

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

: 257957-18-9
4-chloro-2,6-bis(methylthio)pyrimidine

Conditions

Conditions	Yield
Stage #1: 2,4-Bis(methylthio)pyrimidine With bis(2,2,6,6-tetramethylpiperidin-1-yl)magnesium-bis(lithium chloride) complex In tetrahydrofuran at -20℃; for 1h; Inert atmosphere; Stage #2: 1,1,2-Trichloro-1,2,2-trifluoroethane In tetrahydrofuran at -35 - -20℃; for 3h; Inert atmosphere; regioselective reaction;	78%

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

A: 681-25-4
1,2-dichlorotrifluoroethyl fluorosulfate

B Cl2: Cl2

Conditions

Conditions	Yield
With bis(fluorosulfuryl) peroxide; antimony pentafluoride; fluorosulphonic acid at 20 - 30℃; for 0.5h;	A 75.4% B n/a

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

: 41233-93-6
potassium 2-methylbutan-2-olate

A: 2-(2-Chloro-1,1,2-trifluoro-ethoxy)-2-methyl-butane

B: 98481-69-7
2-(2,2-Dichloro-1,1,2-trifluoro-ethoxy)-2-methyl-butane

Conditions

Conditions	Yield
In various solvent(s) for 1h; Ambient temperature; Yields of byproduct given;	A n/a B 75%

...Expand

: 109-97-7
pyrrole

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

: 1-(2,2-dichlorotrifluoroethyl)pyrrole

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 50 - 55℃; for 0.5h;	75%

: 592-41-6
1-hexene

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

: 1,2-dichloro-1,1,2-trifluorooctane

Conditions

Conditions	Yield
With sodium dithionite; sodium hydrogencarbonate In dimethyl sulfoxide at 60℃; for 6h;	74%
With sodium dithionite; water; sodium hydrogencarbonate In acetonitrile at 40 - 45℃; for 20h;	56%
With sodium dithionite; sodium hydrogencarbonate In acetonitrile at 40 - 45℃; for 20h;	56%

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

: 2215-63-6
1-benzyl-3-hydroxy-1H-indazole

: 1300727-50-7
1-benzyl-3-(2,2-dichloro-1,1,2-trifluoroethoxy)-1H-indazole

Conditions

Conditions	Yield
Stage #1: 1-benzyl-3-hydroxy-1H-indazole With potassium tert-butylate In tert-butyl alcohol at 20℃; for 2h; Stage #2: 1,1,2-Trichloro-1,2,2-trifluoroethane In N,N-dimethyl-formamide at 100℃; for 48h;	74%

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

: 3710-30-3
1,7-Octadiene

: 129277-76-5
10,10-Dichloro-9,9,10-trifluoro-dec-1-ene

Conditions

Conditions	Yield
With ammonium peroxydisulfate; sodium formate In N,N-dimethyl-formamide at 45℃; for 4h;	72.5%

: 288-13-1
NH-pyrazole

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

: 909416-36-0
1-(2,2-dichlorotrifluoroethyl)pyrazole

Conditions

Conditions	Yield
With sodium hydride; tetra-(n-butyl)ammonium iodide In N,N-dimethyl-formamide at 50 - 55℃; for 2h;	72%

: 681-84-5
tetramethylorthosilicate

: 76-13-1
1,1,2-Trichloro-1,2,2-trifluoroethane

: 402-43-7
p-trifluoromethylphenyl bromide

: argon

: 35692-32-1
trimethoxy(4-(trifluoromethyl)phenyl)silane

Conditions

Conditions	Yield
With n-butyllithium In diethyl ether; hexane	72%

...Expand

1,1,2-Trichlorotrifluoroethane Consensus Reports

Reported in EPA TSCA Inventory.

1,1,2-Trichlorotrifluoroethane Standards and Recommendations

OSHA PEL: TWA 1000 ppm; STEL 1250 ppm
ACGIH TLV: TWA 1000 ppm; STEL 1250 ppm; Not Classifiable as a Human Carcinogen
DFG MAK: 500 ppm (3900 mg/m³)

1,1,2-Trichlorotrifluoroethane Analytical Methods

For occupational chemical analysis use NIOSH: 1,1,2-Trichloro-1,2,2-trifluoroethane, 1020.

1,1,2-Trichlorotrifluoroethane Specification

The Ethane,1,1,2-trichloro-1,2,2-trifluoro-, with the CAS registry number 76-13-1, is also known as Freon-113. It belongs to the product categories of CFC; Refrigerants; Organics. Its EINECS number is 200-936-1. This chemical's molecular formula is C₂Cl₃F₃ and molecular weight is 187.37. What's more, its systematic name is 1,1,2-trichloro-1,2,2-trifluoroethane. Its classification codes are: (1)Drug / Therapeutic Agent; (2)Reproductive Effect; (3)Skin / Eye Irritant. It is a very unreactive chlorofluorocarbon, that will stay in the atmosphere for a great deal of time if it is released. It was originally used as a coolant in air conditioners and refrigerators, and it was also formerly used as a solvent with which to clean electronics, especially phones. It should be sealed and stored in a cool, ventilated and dry place. Moreover, it should be protected from oxides, heat and fire.

Physical properties of Ethane,1,1,2-trichloro-1,2,2-trifluoro- are: (1)ACD/LogP: 3.20; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 3.19; (4)ACD/LogD (pH 7.4): 3.19; (5)ACD/BCF (pH 5.5): 157.8; (6)ACD/BCF (pH 7.4): 157.8; (7)ACD/KOC (pH 5.5): 1303.23; (8)ACD/KOC (pH 7.4): 1303.23; (9)#H bond acceptors: 0; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 1; (12)Index of Refraction: 1.385; (13)Molar Refractivity: 26.28 cm³; (14)Molar Volume: 112.1 cm³; (15)Polarizability: 10.42×10^-24cm³; (16)Surface Tension: 23 dyne/cm; (17)Density: 1.67 g/cm³; (18)Enthalpy of Vaporization: 27.04 kJ/mol; (19)Boiling Point: 50.9 °C at 760 mmHg; (20)Vapour Pressure: 296 mmHg at 25°C.

Preparation: this chemical can be prepared by 1,1,2,2-tetrachloro-1,2-difluoro-ethane at the temperature of 20 - 25 °C. This reaction will need reagents BrF₃, SbCl₅ and solvent 1,1,2-trichloro-1,2,2-trifluoro-ethane. The yield is about 90%.

Ethane,1,1,2-trichloro-1,2,2-trifluoro- can be prepared by 1,1,2,2-tetrachloro-1,2-difluoro-ethane at the temperature of 20 - 25 °C

Uses of Ethane,1,1,2-trichloro-1,2,2-trifluoro-: it can be used to produce 1,1-dichloro-1,2,2-trifluoro-octane at the temperature of 40 °C. It will need reagents (NH₄)₂S₂O₈, HCO₂Na·2H₂O and solvent dimethylformamide with the reaction time of 3 hours. The yield is about 86.5%.

Ethane,1,1,2-trichloro-1,2,2-trifluoro- can be used to produce 1,1-dichloro-1,2,2-trifluoro-octane at the temperature of 40 °C

When you are using this chemical, please be cautious about it as the following:
This chemical is toxic as it has a danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed. It is toxic to aquatic organisms as it may cause long-term adverse effects in the aquatic environment. Moreover, it is dangerous for the ozone layer. When using it, you need wear suitable protective clothing and gloves. You should refer to manufacturer/supplier for information on recovery/recycling. This material and its container must be disposed of as hazardous waste.

You can still convert the following datas into molecular structure:
(1)SMILES: ClC(F)(F)C(Cl)(Cl)F
(2)Std. InChI: InChI=1S/C2Cl3F3/c3-1(4,6)2(5,7)8
(3)Std. InChIKey: AJDIZQLSFPQPEY-UHFFFAOYSA-N

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LC50	inhalation	> 12pph/2H (120000ppm)		Archives des Maladies Professionnelles de Medecine du Travail et de Securite Sociale. Vol. 29, Pg. 381, 1968.
guinea pig	LDLo	oral	> 10gm/kg (10000mg/kg)		National Technical Information Service. Vol. OTS0520705,
mouse	LC50	inhalation	260gm/m³/2H (260000mg/m³)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Trudy Leningradskogo Sanitarno-Gigienicheskogo Meditsinskogo Instituta. Vol. 75, Pg. 241, 1963.
mouse	LD50	intravenous	9gm/kg (9000mg/kg)	AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	National Technical Information Service. Vol. OTS0520355.
mouse	LD50	unreported	40gm/kg (40000mg/kg)		United States Patent Document. Vol. #4164653.
rabbit	LC50	inhalation	59500ppm/2H (59500ppm)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	National Technical Information Service. Vol. OTS0520343,
rabbit	LD	skin	> 11gm/kg (11000mg/kg)		American Industrial Hygiene Association Journal. Vol. 29, Pg. 521, 1968.
rabbit	LDLo	oral	17gm/kg (17000mg/kg)		American Industrial Hygiene Association Journal. Vol. 29, Pg. 521, 1968.
rat	LC50	inhalation	38500ppm/4H (38500ppm)	BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: EXCITEMENT BEHAVIORAL: ATAXIA	National Technical Information Service. Vol. OTS0520341,
rat	LD50	oral	43gm/kg (43000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: OTHER CHANGES SKIN AND APPENDAGES (SKIN): HAIR: OTHER	Journal of Medicinal Chemistry. Vol. 7, Pg. 378, 1964.

Product Name

1,1,2-Trichlorotrifluoroethane

Synthetic route

1,1,2-Trichlorotrifluoroethane Consensus Reports

1,1,2-Trichlorotrifluoroethane Standards and Recommendations

1,1,2-Trichlorotrifluoroethane Analytical Methods

1,1,2-Trichlorotrifluoroethane Specification

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