1,3-Dihydro-5-phenyl-1,4-benzodiazepin-2-one supplier

Name
1,3-Dihydro-5-phenyl-1,4-benzodiazepin-2-one
EINECS 220-781-3
CAS No. 2898-08-0
Article Data55
CAS DataBase
Density 1.21 g/cm³
Solubility
Melting Point 170-180 °C
Formula C15H12 N2 O
Boiling Point 424.4 °C at 760 mmHg
Molecular Weight 236.273
Flash Point 210.5 °C
Transport Information
Appearance
Safety
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms 1,2-Dihydro-5-phenyl-3H-1,4-benzodiazepin-2-one;1,3-Dihydro-5-phenyl-1,4-benzodiazepin-2-one; 1,3-Dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one;5-Phenyl-1,3-dihydrobenzo[e][1,4]diazepin-2-one;5-Phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one;5-Phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one; Dechlorodemethyldiazepam;Desmethyldechlorodiazepam; NSC 656624; Ro 05-2921; Ro 5-2921
PSA 41.46000
LogP 2.04970

Synthetic route

: 23207-75-2
N-(2-benzoylphenyl)-2-chloroacetamide

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

Conditions

Conditions	Yield
With hexamethylenetetramine; ammonium acetate In ethanol for 6h; Reflux;	95%
With hexamethylenetetramine In ethanol; chloroform	86%
With paraformaldehyde In methanol; toluene	84.7%
With hexamethylenetetramine; ammonium chloride In ethanol for 4h; Reflux;	50%
Multi-step reaction with 2 steps 1: sodium azide / N,N-dimethyl-formamide / 18 h / 20 °C / Inert atmosphere 2: diphenylsilane; 9-phenyl-9-phosphafluorene / 1,4-dioxane / 16 h / 101 °C / Inert atmosphere View Scheme

: 14439-71-5
2'-benzoyl-2-bromo-acetanilide

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

Conditions

Conditions	Yield
With ammonia In methanol Heating;	90%
With ammonia In methanol for 2h; Heating; Yield given;
With ammonium hydroxide In ethanol Yield given;

: 23207-75-2
N-(2-benzoylphenyl)-2-chloroacetamide

A: 23207-85-4
3-amino-1,2-dihydro-2-oxo-4-phenylquinoline

B: 3-(2-Benzoyl-phenyl)-imidazolidin-4-one

C: C33H28N4O4

D: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

Conditions

Conditions	Yield
With hexamethylenetetramine; ammonia In ethanol at 70℃; Further byproducts given;	A n/a B n/a C n/a D 89%

...Expand

: 2185-00-4
1,3-oxazolidine-2,5-dione

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

Conditions

Conditions	Yield
Stage #1: 1,3-oxazolidine-2,5-dione; (2-aminophenyl)(phenyl)methanone With trifluoroacetic acid In toluene at 60℃; for 0.5h; Sealed tube; Stage #2: With triethylamine at 80℃; for 0.5h; Sealed tube;	89%

: 2-azido-N-(2-benzoylphenyl)acetamide

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

Conditions

Conditions	Yield
With 9-phenyl-9-phosphafluorene; diphenylsilane In 1,4-dioxane at 101℃; for 16h; Inert atmosphere;	88%

: 79-04-9
chloroacetyl chloride

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

Conditions

Conditions	Yield
Stage #1: chloroacetyl chloride; (2-aminophenyl)(phenyl)methanone With triethylamine In dichloromethane at 20 - 30℃; for 3h; Stage #2: With ammonia at 25℃;	84.4%
With sodium iodide; ammonia; acetic acid In tetrahydrofuran; chloroform; ethyl acetate

: 598-21-0
2-Bromoacetyl bromide

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

Conditions

Conditions	Yield
Stage #1: 2-Bromoacetyl bromide; (2-aminophenyl)(phenyl)methanone With sodium hydrogencarbonate In chloroform at 0℃; Stage #2: With ammonia In methanol at 0 - 20℃; Heating / reflux;	83%
Stage #1: 2-Bromoacetyl bromide; (2-aminophenyl)(phenyl)methanone In dichloromethane; water Stage #2: With ammonia
With sodium hydroxide In dichloromethane

: 4530-20-5
BOC-glycine

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

Conditions

Conditions	Yield
Stage #1: BOC-glycine; (2-aminophenyl)(phenyl)methanone With dicyclohexyl-carbodiimide In toluene at 150℃; for 0.5h; Microwave irradiation; Stage #2: With trifluoroacetic acid In toluene at 150℃; for 0.333333h; Microwave irradiation;	83%
Stage #1: BOC-glycine; (2-aminophenyl)(phenyl)methanone With dicyclohexyl-carbodiimide In toluene at 150℃; for 1.5h; Microwave irradiation; Stage #2: With trifluoroacetic acid In toluene for 0.333333h;	65%
Stage #1: BOC-glycine With 4-methyl-morpholine; chloroformic acid ethyl ester In tetrahydrofuran at -20℃; for 0.25h; Stage #2: (2-aminophenyl)(phenyl)methanone With 4-methyl-morpholine In tetrahydrofuran at 20℃; Stage #3: With trifluoroacetic acid In dichloromethane at 0 - 20℃;

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

Conditions

Conditions	Yield
	53%
Multi-step reaction with 2 steps 1: NaHCO3 / CH2Cl2 2: 90 percent / NH3 / methanol / Heating View Scheme
Multi-step reaction with 2 steps 1: CH2Cl2 2: aq. NH3 / ethanol View Scheme

: 623-33-6
glycine ethyl ester hydrochloride

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

Conditions

Conditions	Yield
In pyridine for 3h; Dean-Stark; Molecular sieve; Reflux;	52.5%
With pyridine at 100℃;	34%

: 100-97-0
hexamethylenetetramine

: 23207-75-2
N-(2-benzoylphenyl)-2-chloroacetamide

A: 3-(2-Benzoyl-phenyl)-imidazolidin-4-one

B: C33H28N4O4

C: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

Conditions

Conditions	Yield
With urotropin hydrochloride In methanol; water Heating;	A n/a B n/a C 40%

...Expand

: 616-34-2
methoxycarbonylmethylamine

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

Conditions

Conditions	Yield
With pyridine Cyclocondensation;

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: Amino-acetic acid 4'-(2-amino-acetoxymethyl)-[2,2']bipyridinyl-4-ylmethyl ester; compound with trifluoro-acetic acid

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

Conditions

Conditions	Yield
In pyridine Heating;

: 100-47-0
benzonitrile

Cp2Zr(isoprene) (1): Cp2Zr(isoprene) (1)

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: BCl3; AlCl3 / 1,2-dichloro-ethane 2: pyridine View Scheme

: 62-53-3
aniline

Wang resin-bound styrene 4: Wang resin-bound styrene 4

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: BCl3; AlCl3 / 1,2-dichloro-ethane 2: pyridine View Scheme

: C28H37N4O5Pol

A: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

B: 3034-65-9
1-methyl-2,3-dihydro-2-oxo-5-phenyl-1,4-benzodiazepine

Conditions

Conditions	Yield
With water; trifluoroacetic acid In water for 24h; Reflux; solid phase reaction;

: tert-butyl-N-({[2-benzoylphenyl]carbamoyl}methyl)carbamate

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: trifluoroacetic acid / dichloromethane / 2.5 h / 20 °C 2: ammonium acetate; acetic acid / 20 °C View Scheme

: 5504-78-9
2-Glycylamino-benzophenon

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

Conditions

Conditions	Yield
With ammonium acetate; acetic acid at 20℃;	2.32 g

: C16H15N3O3

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

Conditions

Conditions	Yield
With acetic acid In dichloromethane for 12h; Reflux;

: 62-53-3
aniline

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: pyridine / benzene / 4 h / Reflux 2: aluminum (III) chloride / benzene / 10 h / Reflux 3: ammonium chloride; hexamethylenetetramine / ethanol / 4 h / Reflux View Scheme

: 587-65-5
N-chloroacetyl-aniline

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: aluminum (III) chloride / benzene / 10 h / Reflux 2: ammonium chloride; hexamethylenetetramine / ethanol / 4 h / Reflux View Scheme

: 5000-66-8
2-chlorophenacyl bromide

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

: 145084-65-7
1-[2-(2-Chloro-phenyl)-2-oxo-ethyl]-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one

Conditions

Conditions	Yield
With sodium hydroxide; Aliquat 336 In toluene for 6h; Ambient temperature;	100%

: 31949-21-0
bromomethyl 2-methoxyphenyl ketone

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

: 145084-53-3
1-[2-(2-Methoxy-phenyl)-2-oxo-ethyl]-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one

Conditions

Conditions	Yield
With sodium hydroxide; Aliquat 336 In toluene for 6h; Ambient temperature;	100%

: 55117-15-2
2-chloro-6 fluorobenzyl chloride

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

: 713518-29-7
1-(2-chloro-6-fluoro-benzyl)-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 20℃;	100%

: 5292-43-3
bromoacetic acid tert-butyl ester

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

: 149620-85-9
tert-butyl 2-(2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e] [1,4] diazepin-1-yl)acetate

Conditions

Conditions	Yield
With 1-methyl-pyrrolidin-2-one; caesium carbonate at 20℃;	98%

: 927-68-4
bromoethyl acetate

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

: 159586-66-0
acetic acid 2-(2-oxo-5-phenyl-2,3-dihydrobenzo[e][1,4]diazepin-1-yl)ethyl ester

Conditions

Conditions	Yield
Stage #1: 2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one With sodium hydride In N,N-dimethyl-formamide at 20℃; Stage #2: bromoethyl acetate In N,N-dimethyl-formamide at 20℃; for 2h;	97%

: 824-94-2
p-methoxybenzyl chloride

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

: 174698-35-2
2,3-dihydro-1-[4-methoxybenzyl]-2-oxo-5-phenyl-1H-1,4-benzodiazepine

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 16h;	95%
With potassium carbonate In water; ethyl acetate; N,N-dimethyl-formamide
Stage #1: 2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 0.333333h; Stage #2: p-methoxybenzyl chloride In N,N-dimethyl-formamide; mineral oil at 0℃; for 3.5h;	1.262 g
Stage #1: 2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.333333h; Stage #2: p-methoxybenzyl chloride In N,N-dimethyl-formamide; mineral oil at 20℃; for 3.5h;	1.262 g

: 27578-60-5
1-(2-aminoethyl)piperidine

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

: 2-(2-piperidin-1-ylethylamino)-5-phenyl-3H-1,4-benzodiazepine

Conditions

Conditions	Yield
With titanium tetrachloride; methoxybenzene In dichloromethane at 100℃; for 0.0833333h; microwave irradiation;	95%

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

: 2,4,6-trifluorobenzyl chloride

: 713518-32-2
5-phenyl-1-(2,4,6-trifluoro-benzyl)-1,3-dihydro-benzo[e][1,4]diazepin-2-one

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 20℃;	94%

: 74-87-3
methylene chloride

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

: 3034-65-9
1-methyl-2,3-dihydro-2-oxo-5-phenyl-1,4-benzodiazepine

Conditions

Conditions	Yield
With sodium hydroxide; Aliquat 336 In toluene at 20 - 25℃; for 4h;	93%

: 109-01-3
1-methyl-piperazine

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

: 2-(4-methylpiperazin-1-yl)-5-phenyl-3H-1,4-benzodiazepine

Conditions

Conditions	Yield
With titanium tetrachloride; methoxybenzene In dichloromethane at 100℃; for 1h;	93%

: 4584-46-7
(2-chloroethyl)dimethylamine hydrochloride

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

: 2,3-dihydro-1-(2-dimethylaminoethyl)-5-phenyl-1H-1,4-benzodiazepin-2-one

Conditions

Conditions	Yield
With potassium iodide In hexane; water; N,N-dimethyl-formamide; mineral oil	93%
With potassium iodide In hexane; water; N,N-dimethyl-formamide; mineral oil	93%
With potassium iodide In hexane; water; N,N-dimethyl-formamide; mineral oil	93%

: 70-11-1
α-bromoacetophenone

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

: 145084-40-8
1,3-dihydro-1-phenacyl-5-phenyl-2H-1,4-benzodiazepin-2-one

Conditions

Conditions	Yield
With sodium hydroxide; Aliquat 336 In toluene for 6h; Ambient temperature;	90%

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

: 2894-61-3
7-bromo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one

Conditions

Conditions	Yield
With sulfuric acid; bromine In acetic acid at 20℃; for 48h;	90%
With sulfuric acid; bromine In acetic acid	65.9%

: 5162-44-7
1-bromo-4-butene

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

: 328917-83-5
1-(but-3-en-1-yl)-5-phenyl-1H-benzo[e][1,4]diazepin-2-one

Conditions

Conditions	Yield
Stage #1: 2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 1h; Inert atmosphere; Stage #2: 1-bromo-4-butene In N,N-dimethyl-formamide at 20℃; for 12h; Inert atmosphere;	89%
Stage #1: 2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one With sodium hydride In N,N-dimethyl-formamide at 0℃; for 1h; Inert atmosphere; Stage #2: 1-bromo-4-butene In N,N-dimethyl-formamide at 20℃; for 12h; Inert atmosphere;

: 105-36-2
ethyl bromoacetate

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

: 497873-44-6
(2-oxo-5-phenyl-2,3-dihydrobenzo[e][1,4]diazepin-1-yl)acetic acid ethyl ester

Conditions

Conditions	Yield
Stage #1: 2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one With sodium hydride In N,N-dimethyl-formamide at 20℃; for 1h; Stage #2: ethyl bromoacetate In N,N-dimethyl-formamide at 20℃; for 1h;	88%
Stage #1: 2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 1h; Inert atmosphere; Stage #2: ethyl bromoacetate In N,N-dimethyl-formamide at 20℃; for 12h; Inert atmosphere;	64%

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

: 146-22-5
nitrazepam

Conditions

Conditions	Yield
With 3-(ethoxycarbonyl)-1-(5-methyl-5-(nitrosooxy)hexyl)pyridin-1-ium bis(trifluoromethanesulfonyl)imide at 20℃; for 5h; Ionic liquid;	88%

: 1242071-55-1
methyl 2-(((tert-butoxycarbonyl)oxy)methyl)acrylate

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

: methyl 2-[2-(2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-5-yl)benzyl]acrylate

Conditions

Conditions	Yield
With bromopentacarbonylmanganese(I); sodium acetate In 1,4-dioxane at 80℃; for 16h; Inert atmosphere; Schlenk technique;	85%

: N,N,N-(ferrocenylmethyl)trimethylammonium iodide

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

: 1350644-53-9
1,3-dihydro-1-ferrocenylmethyl-5-phenyl-2H-1,4-benzodiazepin-2-one

Conditions

Conditions	Yield
With potassium tert-butoxide In N,N-dimethyl-formamide under N2; t-BuOK added to soln. of benzodiazepine in freshly distd. DMF at 0°C; stirred at 0°C for 30 min; Fe complex in DMF addedat 20°C; heated at 150°C for 4 h; aq. HCl added until neutralization; extd. by CH2Cl2; org. layers dried (MgSO4); evapd.; purified by column chromy. (ethyl acetate-petroleum ether 5:5); elem. anal.;	84%

: 905718-45-8
[(4-nitrophenyl)(phenyl)iodonium trifluoromethanesulfonate]

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

: 1-(4-nitrophenyl)-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one

Conditions

Conditions	Yield
With ammonium hydroxide In 1,2-dichloro-ethane at 20℃; for 0.5h; Solvent; Reagent/catalyst; Inert atmosphere;	82%

: 1119-51-3
bromopentene

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

: 328917-81-3
1-(pent-4-en-1-yl)-5-phenyl-1H-benzo[e][1,4]diazepin-2-one

Conditions

Conditions	Yield
Stage #1: 2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 1h; Inert atmosphere; Stage #2: bromopentene In N,N-dimethyl-formamide at 20℃; for 12h; Inert atmosphere;	81%
Stage #1: 2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one With sodium hydride In N,N-dimethyl-formamide at 0℃; for 1h; Inert atmosphere; Stage #2: bromopentene In N,N-dimethyl-formamide at 20℃; for 12h; Inert atmosphere;

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

: 4547-02-8
7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-thione

Conditions

Conditions	Yield
Stage #1: 2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one With aluminum (III) chloride; chlorine In dichloromethane at 10 - 20℃; Stage #2: With sodiumsulfide nonahydrate; tetrabutylammomium bromide; dihydrogen peroxide for 2h; Reflux;	78.7%

: 51012-65-8
2-bromo-1-o-tolylethanone

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

: 145084-43-1
1,3-dihydro-1-(2'-methylphenacyl)-5-phenyl-2H-1,4-benzodiazepin-2-one

Conditions

Conditions	Yield
With sodium hydroxide; Aliquat 336 In toluene for 6h; Ambient temperature;	78%

1,3-Dihydro-5-phenyl-1,4-benzodiazepin-2-one Chemical Properties

Molecular Structure of 1,3-Dihydro-5-phenyl-1,4-benzodiazepin-2-one (CAS No.2898-08-0):

Molecular Formula: C₁₅H₁₂N₂O
Molecular Weight: 236.2686
CAS No: 2898-08-0
IUPAC Name: 5-Phenyl-1,3-dihydro-1,4-benzodiazepin-2-one
H bond acceptors: 3
H bond donors: 1
Freely Rotating Bonds: 1
Polar Surface Area: 32.67 Å²
Index of Refraction: 1.647
Molar Refractivity: 70.98 cm³
Molar Volume: 195.2 cm³
Surface Tension: 48.1 dyne/cm
Density: 1.21 g/cm³
Flash Point: 210.5 °C
Enthalpy of Vaporization: 67.89 kJ/mol
Boiling Point: 424.4 °C at 760 mmHg
Vapour Pressure: 2.08E-07 mmHg at 25°C
InChI: InChI=1/C₁₅H₁₂N₂O/c18-14-10-16-15(11-6-2-1-3-7-11)12-8-4-5-9-13(12)17-14/h1-9H,10H2,(H,17,18)
InChIKey: IVUAAOBNUNMJQC-UHFFFAOYAK
Std. InChI: InChI=1S/C₁₅H₁₂N₂O/c18-14-10-16-15(11-6-2-1-3-7-11)12-8-4-5-9-13(12)17-14/h1-9H,10H2,(H,17,18)
Std. InChIKey: IVUAAOBNUNMJQC-UHFFFAOYSA-N
Product Categories: Pharmacetical

1,3-Dihydro-5-phenyl-1,4-benzodiazepin-2-one Specification

1,3-Dihydro-5-phenyl-1,4-benzodiazepin-2-one (CAS No.2898-08-0), its synonyms are 1,3-Dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one ; 2H-1,4-benzodiazepin-2-one, 1,3-dihydro-5-phenyl- ; 5-Phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one ; 5-Phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one ; 2,3-Dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

Product Name

1,3-Dihydro-5-phenyl-1,4-benzodiazepin-2-one

Synthetic route

1,3-Dihydro-5-phenyl-1,4-benzodiazepin-2-one Chemical Properties

1,3-Dihydro-5-phenyl-1,4-benzodiazepin-2-one Specification

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